The origin and evolution of Life in the universe

Resultado final

Inform the Project Officer on publishing each call for proposals, by sending the link to the Euraxess website and a screen shot of the related call announcement.

Publicaciones

An X-ray spectroscopy study of structural stability of superhydrogenated pyrene derivatives

Autores: Yining Huo, Mónica K Espinoza Cangahuala, Vicente Zamudio-Bayer, Marcelo Goulart, Markus Kubin, Martin Timm, J Tobias Lau, Bernd von Issendorff, Ronnie Hoekstra, Shirin Faraji, Thomas Schlathölter
Publicado en: Monthly Notices of the Royal Astronomical Society, Edición 523, 2023, Página(s) 865-875, ISSN 0035-8711
Editor: Blackwell Publishing Inc.
DOI: 10.1093/mnras/stad1341

Enantioselective Self-Replicators

Autores: Shuo Yang, Yannick Geiger, Marc Geerts, Marcel J. Eleveld, Armin Kiani, Sijbren Otto
Publicado en: Journal of the American Chemical Society, Edición 145, 2023, Página(s) 16889-16898, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.3c05472

Impact of ancestral sequence reconstruction on mechanistic and structural enzymology

Autores: Callum R. Nicoll, Marta Massari, Marco W. Fraaije, Maria Laura Mascotti, Andrea Mattevi
Publicado en: Current Opinion in Structural Biology, Edición 82, 2024, Página(s) 102669, ISSN 0959-440X
Editor: Elsevier BV
DOI: 10.1016/j.sbi.2023.102669

Achieving Control in Micro-/Nanomotor Mobility

Autores: Alexander D. Fusi, Yudong Li, Dr. A. Llopis-Lorente, Dr. Tania Patiño, Prof. Dr. Jan C. M. van Hest, Dr. Loai K. E. A. Abdelmohsen
Publicado en: Angewandte ChemieBron:Wiley Online Library: Complete Journals, Edición volume 135, issue 5, 2023, ISSN 0044-8249
Editor: John Wiley and Sons,
DOI: 10.1002/ange.202214754

Exploring Intra- and Inter-Regional Interactions in the IDP α-Synuclein Using smFRET and MD Simulations

Autores: Gobert Heesink, Mirjam J. Marseille, Mohammad A. A. Fakhree, Mark D. Driver, Kirsten A. van Leijenhorst-Groener, Patrick R. Onck, Christian Blum, Mireille M.A.E. Claessens
Publicado en: Biomacromolecules, Edición 24, 2023, Página(s) 3680-3688, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.3c00404

Temporal segregation of biosynthetic processes is responsible for metabolic oscillations during the budding yeast cell cycle

Autores: Vakil Takhaveev, Serdar Özsezen, Edward N. Smith, Andre Zylstra, Marten L. Chaillet, Haoqi Chen, Alexandros Papagiannakis, Andreas Milias-Argeitis, Matthias Heinemann
Publicado en: Nature Metabolism, Edición 5, 2023, Página(s) 294-313, ISSN 2522-5812
Editor: Springer
DOI: 10.1038/s42255-023-00741-x

Vanillyl alcohol oxidase from Diplodia corticola: Residues Ala420 and Glu466 allow for efficient catalysis of syringyl derivatives

Autores: Daniel Eggerichs, Nils Weindorf, Maria Laura Mascotti, Natalie Welzel, Marco W. Fraaije, Dirk Tischler
Publicado en: Journal of Biological Chemistry, Edición 299, 2024, Página(s) 104898, ISSN 0021-9258
Editor: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.jbc.2023.104898

Asymmetric Synthesis of Chiral‐at‐P Alkenylphosphonamidates through Nickel‐Catalyzed C−P Coupling of Phosphoramidites and Alkenyl Halides

Autores: Xiao‐Bing Chen, Damián Padín, Charlotte N. Stindt, Ben L. Feringa
Publicado en: Angewandte Chemie International Edition, Edición 62, 2023, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202307450

Bacterial multi‐solute transporters

Autores: Dirk J. Slotboom, Thijs W. Ettema, Mark Nijland, Chancievan Thangaratnarajah
Publicado en: FEBS Letters, Edición 594, 2023, Página(s) 3898-3907, ISSN 0014-5793
Editor: Elsevier BV
DOI: 10.1002/1873-3468.13912

Author Correction: CRISPR-based transcriptional activation tool for silent genes in filamentous fungi

Autores: László Mózsik, Mirthe Hoekzema, Niels A.W. de Kok, Roel A.L. Bovenberg, Yvonne Nygård, Arnold J.M. Driessen
Publicado en: Scientific Reports, Edición vol 11, issue 1, 2021, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-021-99654-6

Cryo-EM studies of membrane proteins at 200 keV

Autores: Chancievan Thangaratnarajah, Jan Rheinberger, Cristina Paulino
Publicado en: Current Opinion in Structural Biology, Edición 76, 2024, Página(s) 102440, ISSN 0959-440X
Editor: Elsevier BV
DOI: 10.1016/j.sbi.2022.102440

All-Photochemical Rotation of Molecular Motors with a Phosphorus Stereoelement

Autores: Gregory B. Boursalian, Eise R. Nijboer, Ruth Dorel, Lukas Pfeifer, Omer Markovitch, Alex Blokhuis, Ben L. Feringa
Publicado en: Journal of the American Chemical Society, Edición 142, 2023, Página(s) 16868-16876, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.0c08249

Role of Curvature‐Sensing Proteins in the Uptake of Nanoparticles with Different Mechanical Properties

Autores: Daphne Montizaan, Catherine Saunders, Keni Yang, Sajitha Sasidharan, Sourav Maity, Catharina Reker‐Smit, Marc C. A. Stuart, Costanza Montis, Debora Berti, Wouter H. Roos, Anna Salvati
Publicado en: Small, Edición 19, 2023, ISSN 1613-6810
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202303267

Quorum sensing communication between lipid-based artificial cells

Autores: Antoni Llopis-Lorente, Bastiaan C. Buddingh', R. Martínez-Máñez, Jan C. M. van Hest, Loai K. E. Abdelmohsen
Publicado en: Chemical Communications, Edición 59, 2024, Página(s) 579-582, ISSN 1359-7345
Editor: Royal Society of Chemistry
DOI: 10.1039/d2cc05367e

Water content of rocky exoplanets in the habitable zone

Autores: Ádám Boldog, Vera Dobos, László L. Kiss, Marijn van der Perk, Amy C. Barr
Publicado en: Astronomy & Astrophysics, Edición 681, 2024, Página(s) A109, ISSN 0004-6361
Editor: Springer Verlag
DOI: 10.1051/0004-6361/202346988

A comparative laboratory study of soft X-ray-induced ionization and fragmentation of five small PAH cations

Autores: Yining Huo, Mónica K. Espinoza Cangahuala, Vicente Zamudio-Bayer, Marcelo Goulart, Markus Kubin, Martin Timm, J. Tobias Lau, Bernd von Issendorff, Ronnie Hoekstra, Shirin Faraji, Thomas Schlathölter
Publicado en: The European Physical Journal D, Edición 77, 2023, ISSN 1434-6060
Editor: Springer Verlag
DOI: 10.1140/epjd/s10053-023-00763-w

Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer

Autores: Sotiria Tavoulari, Tom J.J. Schirris, Vasiliki Mavridou, Chancievan Thangaratnarajah, Martin S. King, Daniel T.D. Jones, Shujing Ding, Ian M. Fearnley, Edmund R.S. Kunji
Publicado en: Molecular Metabolism, Edición 60, 2022, Página(s) 101469, ISSN 2212-8778
Editor: Elsevier GmbH
DOI: 10.1016/j.molmet.2022.101469

Lipid-Based Nanoparticle Functionalization with Coiled-Coil Peptides for <i>In Vitro</i> and <i>In Vivo</i> Drug Delivery

Autores: Dennis Aschmann; Renzo A. Knol; Alexander Kros
Publicado en: Accounts of Chemical Research, Edición 57, 8,, 2024, Página(s) 1098–1110, ISSN 0001-4842
Editor: American Chemical Society
DOI: 10.1021/acs.accounts.3c00769

Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension

Autores: Apirat Chaikuad, Chancievan Thangaratnarajah, Frank von Delft, Alex N. Bullock
Publicado en: Scientific Reports, Edición 9, 2022, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-019-54830-7

Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs

Autores: Callum R Nicoll, Gautier Bailleul, Filippo Fiorentini, María Laura Mascotti, Marco W Fraaije*, Andrea Mattevi
Publicado en: Nature Structural & Molecular Biology, Edición vol 27, 2019, Página(s) 14-24, ISSN 1545-9985
Editor: Nature Publishing Group
DOI: 10.1038/s41594-019-0347-2

Fitness landscape of substrate-adaptive mutations in evolved amino acid-polyamine-organocation transporters

Autores: Foteini Karapanagioti, Úlfur Águst Atlason, Dirk J Slotboom, Bert Poolman, Sebastian Obermaier
Publicado en: eLife, Edición 13, 2024, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.93971.3

Stoichiometry alone can steer supramolecular systems on complex free energy surfaces with high selectivity

Autores: Dávid Komáromy, Theodora Tiemersma-Wegman, Johan Kemmink, Giuseppe Portale, Paul R. Adamski, Alex Blokhuis, Friso S. Aalbers, Ivana Marić, Guillermo Monreal Santiago, Jim Ottelé, Ankush Sood, Vittorio Saggiomo, Bin Liu, Pieter van der Meulen, Sijbren Otto
Publicado en: Chem, Edición 7, 2023, Página(s) 1933-1951, ISSN 2451-9294
Editor: Elsevier
DOI: 10.1016/j.chempr.2021.05.020

CRISPR-based transcriptional activation tool for silent genes in filamentous fungi

Autores: László Mózsik, Mirthe Hoekzema, Niels A W de Kok, Roel A L Bovenberg, Yvonne Nygård, Arnold J M Driessen
Publicado en: Scientific Reports, Edición vol 11, issue 1, 2021, Página(s) 13 pages, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-020-80864-3

Natamycin sequesters ergosterol and interferes with substrate transport by the lysine transporter Lyp1 from yeast

Autores: Maria Szomek, Peter Reinholdt, Hanna-Loisa Walther, Holger A. Scheidt, Peter Müller, Sebastian Obermaier, Bert Poolman, Jacob Kongsted, Daniel Wüstner
Publicado en: Biochimica et Biophysica Acta (BBA) - Biomembranes, Edición 1864, 2024, Página(s) 184012, ISSN 0005-2736
Editor: Elsevier BV
DOI: 10.1016/j.bbamem.2022.184012

Bidirectional ATP-driven transport of cobalamin by the mycobacterial ABC transporter BacA

Autores: Mark Nijland; Solène N. Lefebvre; Chancievan Thangaratnarajah; Dirk J. Slotboom
Publicado en: Nature Communications, Edición 15 / 1, 2024, Página(s) 9 pages, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-024-46917-1

Reconstructing the evolutionary history of F420-dependent dehydrogenases

Autores: M. Laura Mascotti, Hemant Kumar, Quoc-Thai Nguyen, Maximiliano Juri Ayub, Marco W. Fraaije
Publicado en: Scientific Reports, Edición 8, 2022, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-018-35590-2

Investigating the biochemical signatures and physiological roles of the FMO family using molecular phylogeny

Autores: C.R. Nicoll, M.L. Mascotti
Publicado en: BBA Advances, Edición 4, 2023, Página(s) 100108, ISSN 2667-1603
Editor: Elsevier
DOI: 10.1016/j.bbadva.2023.100108

One Soai reaction, two mechanisms?

Autores: Yannick Geiger
Publicado en: Chemical Society Reviews, Edición 14604744, 2022, ISSN 1460-4744
Editor: Royal Society of Chemistry
DOI: 10.1039/d1cs01038g

Endocytosis-like DNA uptake by cell wall-deficient bacteria

Autores: Renée Kapteijn, Shraddha Shitut, Dennis Aschmann, Le Zhang, Marit de Beer, Deniz Daviran, Rona Roverts, Anat Akiva, Gilles P. van Wezel, Alexander Kros, Dennis Claessen
Publicado en: Nature Communications, Edición 13, 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-33054-w

The topological shadow of $${{{\mathbb {F}}}_1}$$-geometry: congruence spaces

Autores: Oliver Lorscheid, Samarpita Ray
Publicado en: Mathematische Zeitschrift, Edición 306, 2024, ISSN 0025-5874
Editor: Springer Verlag
DOI: 10.1007/s00209-023-03425-0

Hybrid Biodegradable Nanomotors through Compartmentalized Synthesis

Autores: Imke AB Pijpers, Shoupeng Cao, Antoni Llopis-Lorente, Jianzhi Zhu, Shidong Song, Rick RM Joosten, Fenghua Meng, Heiner Friedrich, David S Williams, Samuel Sánchez, Jan CM van Hest, Loai KEA Abdelmohsen
Publicado en: Nano Letters, Edición issue 20 / 6, 2020, Página(s) 4472-4480
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.0c01268

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