The origin and evolution of Life in the universe

Deliverables

Inform the Project Officer on publishing each call for proposals, by sending the link to the Euraxess website and a screen shot of the related call announcement.

Publications

An X-ray spectroscopy study of structural stability of superhydrogenated pyrene derivatives

Author(s): Yining Huo, Mónica K Espinoza Cangahuala, Vicente Zamudio-Bayer, Marcelo Goulart, Markus Kubin, Martin Timm, J Tobias Lau, Bernd von Issendorff, Ronnie Hoekstra, Shirin Faraji, Thomas Schlathölter
Published in: Monthly Notices of the Royal Astronomical Society, Issue 523, 2023, Page(s) 865-875, ISSN 0035-8711
Publisher: Blackwell Publishing Inc.
DOI: 10.1093/mnras/stad1341

Enantioselective Self-Replicators

Author(s): Shuo Yang, Yannick Geiger, Marc Geerts, Marcel J. Eleveld, Armin Kiani, Sijbren Otto
Published in: Journal of the American Chemical Society, Issue 145, 2023, Page(s) 16889-16898, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.3c05472

Impact of ancestral sequence reconstruction on mechanistic and structural enzymology

Author(s): Callum R. Nicoll, Marta Massari, Marco W. Fraaije, Maria Laura Mascotti, Andrea Mattevi
Published in: Current Opinion in Structural Biology, Issue 82, 2024, Page(s) 102669, ISSN 0959-440X
Publisher: Elsevier BV
DOI: 10.1016/j.sbi.2023.102669

Achieving Control in Micro-/Nanomotor Mobility

Author(s): Alexander D. Fusi, Yudong Li, Dr. A. Llopis-Lorente, Dr. Tania Patiño, Prof. Dr. Jan C. M. van Hest, Dr. Loai K. E. A. Abdelmohsen
Published in: Angewandte ChemieBron:Wiley Online Library: Complete Journals, Issue volume 135, issue 5, 2023, ISSN 0044-8249
Publisher: John Wiley and Sons,
DOI: 10.1002/ange.202214754

Exploring Intra- and Inter-Regional Interactions in the IDP α-Synuclein Using smFRET and MD Simulations

Author(s): Gobert Heesink, Mirjam J. Marseille, Mohammad A. A. Fakhree, Mark D. Driver, Kirsten A. van Leijenhorst-Groener, Patrick R. Onck, Christian Blum, Mireille M.A.E. Claessens
Published in: Biomacromolecules, Issue 24, 2023, Page(s) 3680-3688, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.3c00404

Temporal segregation of biosynthetic processes is responsible for metabolic oscillations during the budding yeast cell cycle

Author(s): Vakil Takhaveev, Serdar Özsezen, Edward N. Smith, Andre Zylstra, Marten L. Chaillet, Haoqi Chen, Alexandros Papagiannakis, Andreas Milias-Argeitis, Matthias Heinemann
Published in: Nature Metabolism, Issue 5, 2023, Page(s) 294-313, ISSN 2522-5812
Publisher: Springer
DOI: 10.1038/s42255-023-00741-x

Vanillyl alcohol oxidase from Diplodia corticola: Residues Ala420 and Glu466 allow for efficient catalysis of syringyl derivatives

Author(s): Daniel Eggerichs, Nils Weindorf, Maria Laura Mascotti, Natalie Welzel, Marco W. Fraaije, Dirk Tischler
Published in: Journal of Biological Chemistry, Issue 299, 2024, Page(s) 104898, ISSN 0021-9258
Publisher: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.jbc.2023.104898

Asymmetric Synthesis of Chiral‐at‐P Alkenylphosphonamidates through Nickel‐Catalyzed C−P Coupling of Phosphoramidites and Alkenyl Halides

Author(s): Xiao‐Bing Chen, Damián Padín, Charlotte N. Stindt, Ben L. Feringa
Published in: Angewandte Chemie International Edition, Issue 62, 2023, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202307450

Bacterial multi‐solute transporters

Author(s): Dirk J. Slotboom, Thijs W. Ettema, Mark Nijland, Chancievan Thangaratnarajah
Published in: FEBS Letters, Issue 594, 2023, Page(s) 3898-3907, ISSN 0014-5793
Publisher: Elsevier BV
DOI: 10.1002/1873-3468.13912

Author Correction: CRISPR-based transcriptional activation tool for silent genes in filamentous fungi

Author(s): László Mózsik, Mirthe Hoekzema, Niels A.W. de Kok, Roel A.L. Bovenberg, Yvonne Nygård, Arnold J.M. Driessen
Published in: Scientific Reports, Issue vol 11, issue 1, 2021, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-99654-6

Cryo-EM studies of membrane proteins at 200 keV

Author(s): Chancievan Thangaratnarajah, Jan Rheinberger, Cristina Paulino
Published in: Current Opinion in Structural Biology, Issue 76, 2024, Page(s) 102440, ISSN 0959-440X
Publisher: Elsevier BV
DOI: 10.1016/j.sbi.2022.102440

All-Photochemical Rotation of Molecular Motors with a Phosphorus Stereoelement

Author(s): Gregory B. Boursalian, Eise R. Nijboer, Ruth Dorel, Lukas Pfeifer, Omer Markovitch, Alex Blokhuis, Ben L. Feringa
Published in: Journal of the American Chemical Society, Issue 142, 2023, Page(s) 16868-16876, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.0c08249

Role of Curvature‐Sensing Proteins in the Uptake of Nanoparticles with Different Mechanical Properties

Author(s): Daphne Montizaan, Catherine Saunders, Keni Yang, Sajitha Sasidharan, Sourav Maity, Catharina Reker‐Smit, Marc C. A. Stuart, Costanza Montis, Debora Berti, Wouter H. Roos, Anna Salvati
Published in: Small, Issue 19, 2023, ISSN 1613-6810
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202303267

Quorum sensing communication between lipid-based artificial cells

Author(s): Antoni Llopis-Lorente, Bastiaan C. Buddingh', R. Martínez-Máñez, Jan C. M. van Hest, Loai K. E. Abdelmohsen
Published in: Chemical Communications, Issue 59, 2024, Page(s) 579-582, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2cc05367e

Water content of rocky exoplanets in the habitable zone

Author(s): Ádám Boldog, Vera Dobos, László L. Kiss, Marijn van der Perk, Amy C. Barr
Published in: Astronomy & Astrophysics, Issue 681, 2024, Page(s) A109, ISSN 0004-6361
Publisher: Springer Verlag
DOI: 10.1051/0004-6361/202346988

A comparative laboratory study of soft X-ray-induced ionization and fragmentation of five small PAH cations

Author(s): Yining Huo, Mónica K. Espinoza Cangahuala, Vicente Zamudio-Bayer, Marcelo Goulart, Markus Kubin, Martin Timm, J. Tobias Lau, Bernd von Issendorff, Ronnie Hoekstra, Shirin Faraji, Thomas Schlathölter
Published in: The European Physical Journal D, Issue 77, 2023, ISSN 1434-6060
Publisher: Springer Verlag
DOI: 10.1140/epjd/s10053-023-00763-w

Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer

Author(s): Sotiria Tavoulari, Tom J.J. Schirris, Vasiliki Mavridou, Chancievan Thangaratnarajah, Martin S. King, Daniel T.D. Jones, Shujing Ding, Ian M. Fearnley, Edmund R.S. Kunji
Published in: Molecular Metabolism, Issue 60, 2022, Page(s) 101469, ISSN 2212-8778
Publisher: Elsevier GmbH
DOI: 10.1016/j.molmet.2022.101469

Lipid-Based Nanoparticle Functionalization with Coiled-Coil Peptides for <i>In Vitro</i> and <i>In Vivo</i> Drug Delivery

Author(s): Dennis Aschmann; Renzo A. Knol; Alexander Kros
Published in: Accounts of Chemical Research, Issue 57, 8,, 2024, Page(s) 1098–1110, ISSN 0001-4842
Publisher: American Chemical Society
DOI: 10.1021/acs.accounts.3c00769

Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension

Author(s): Apirat Chaikuad, Chancievan Thangaratnarajah, Frank von Delft, Alex N. Bullock
Published in: Scientific Reports, Issue 9, 2022, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-54830-7

Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs

Author(s): Callum R Nicoll, Gautier Bailleul, Filippo Fiorentini, María Laura Mascotti, Marco W Fraaije*, Andrea Mattevi
Published in: Nature Structural & Molecular Biology, Issue vol 27, 2019, Page(s) 14-24, ISSN 1545-9985
Publisher: Nature Publishing Group
DOI: 10.1038/s41594-019-0347-2

Fitness landscape of substrate-adaptive mutations in evolved amino acid-polyamine-organocation transporters

Author(s): Foteini Karapanagioti, Úlfur Águst Atlason, Dirk J Slotboom, Bert Poolman, Sebastian Obermaier
Published in: eLife, Issue 13, 2024, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.93971.3

Stoichiometry alone can steer supramolecular systems on complex free energy surfaces with high selectivity

Author(s): Dávid Komáromy, Theodora Tiemersma-Wegman, Johan Kemmink, Giuseppe Portale, Paul R. Adamski, Alex Blokhuis, Friso S. Aalbers, Ivana Marić, Guillermo Monreal Santiago, Jim Ottelé, Ankush Sood, Vittorio Saggiomo, Bin Liu, Pieter van der Meulen, Sijbren Otto
Published in: Chem, Issue 7, 2023, Page(s) 1933-1951, ISSN 2451-9294
Publisher: Elsevier
DOI: 10.1016/j.chempr.2021.05.020

CRISPR-based transcriptional activation tool for silent genes in filamentous fungi

Author(s): László Mózsik, Mirthe Hoekzema, Niels A W de Kok, Roel A L Bovenberg, Yvonne Nygård, Arnold J M Driessen
Published in: Scientific Reports, Issue vol 11, issue 1, 2021, Page(s) 13 pages, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-80864-3

Natamycin sequesters ergosterol and interferes with substrate transport by the lysine transporter Lyp1 from yeast

Author(s): Maria Szomek, Peter Reinholdt, Hanna-Loisa Walther, Holger A. Scheidt, Peter Müller, Sebastian Obermaier, Bert Poolman, Jacob Kongsted, Daniel Wüstner
Published in: Biochimica et Biophysica Acta (BBA) - Biomembranes, Issue 1864, 2024, Page(s) 184012, ISSN 0005-2736
Publisher: Elsevier BV
DOI: 10.1016/j.bbamem.2022.184012

Bidirectional ATP-driven transport of cobalamin by the mycobacterial ABC transporter BacA

Author(s): Mark Nijland; Solène N. Lefebvre; Chancievan Thangaratnarajah; Dirk J. Slotboom
Published in: Nature Communications, Issue 15 / 1, 2024, Page(s) 9 pages, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-46917-1

Reconstructing the evolutionary history of F420-dependent dehydrogenases

Author(s): M. Laura Mascotti, Hemant Kumar, Quoc-Thai Nguyen, Maximiliano Juri Ayub, Marco W. Fraaije
Published in: Scientific Reports, Issue 8, 2022, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-018-35590-2

Investigating the biochemical signatures and physiological roles of the FMO family using molecular phylogeny

Author(s): C.R. Nicoll, M.L. Mascotti
Published in: BBA Advances, Issue 4, 2023, Page(s) 100108, ISSN 2667-1603
Publisher: Elsevier
DOI: 10.1016/j.bbadva.2023.100108

One Soai reaction, two mechanisms?

Author(s): Yannick Geiger
Published in: Chemical Society Reviews, Issue 14604744, 2022, ISSN 1460-4744
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1cs01038g

Endocytosis-like DNA uptake by cell wall-deficient bacteria

Author(s): Renée Kapteijn, Shraddha Shitut, Dennis Aschmann, Le Zhang, Marit de Beer, Deniz Daviran, Rona Roverts, Anat Akiva, Gilles P. van Wezel, Alexander Kros, Dennis Claessen
Published in: Nature Communications, Issue 13, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-33054-w

The topological shadow of $${{{\mathbb {F}}}_1}$$-geometry: congruence spaces

Author(s): Oliver Lorscheid, Samarpita Ray
Published in: Mathematische Zeitschrift, Issue 306, 2024, ISSN 0025-5874
Publisher: Springer Verlag
DOI: 10.1007/s00209-023-03425-0

Hybrid Biodegradable Nanomotors through Compartmentalized Synthesis

Author(s): Imke AB Pijpers, Shoupeng Cao, Antoni Llopis-Lorente, Jianzhi Zhu, Shidong Song, Rick RM Joosten, Fenghua Meng, Heiner Friedrich, David S Williams, Samuel Sánchez, Jan CM van Hest, Loai KEA Abdelmohsen
Published in: Nano Letters, Issue issue 20 / 6, 2020, Page(s) 4472-4480
Publisher: American Chemical Society
DOI: 10.1021/acs.nanolett.0c01268

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