Massive Reverse Genomics to Decipher Gene Regulatory Grammar

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

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Website

Project website for visibility, raising awareness and dissemination purposes. The website will be maintained throughout the execution and will stay alive at least 2 years after the project end.

Unnatural enhancer data-set and report

Natural enhancer data-set and report

Bottom-up data-set report

Top-down data-set report

Publicaciones

The interaction landscape between transcription factors and the nucleosome

Autores: Fangjie Zhu, Lucas Farnung, Eevi Kaasinen, Biswajyoti Sahu, Yimeng Yin, Bei Wei, Svetlana Dodonova, Patrick Cramer, Jussi Taipale
Publicado en: Nature, 2017, ISSN 2520-1158
Editor: Nature
DOI: 10.1101/240598

Gene expression variability across cells and species shapes innate immunity

Autores: Tzachi Hagai, Xi Chen, Ricardo J. Miragaia, Tomas Gomes, Raghd Rostom, Natalia Kunowska, Valentina Proserpio, Giacomo Donati, Lara Bossini-Castillo, Guy Naamati, Guy Emerton, Gosia Trynka, Ivanela Kondova, Mike Denis, Sarah A Teichmann
Publicado en: Nature, 2017, ISSN 2520-1158
Editor: Nature
DOI: 10.1101/137992

Genome-wide CRISPR screens in T helper cells reveal pervasive cross-talk between activation and differentiation

Autores: Johan Henriksson, Xi Chen, Tomás Gomes, Ubaid Ullah, Kerstin B Meyer, Ricardo Miragaia, Graham Duddy, Jhuma Pramanik, Kosuke Yusa, Riita Lahesmaa, Sarah A. Teichmann
Publicado en: Cell, 2017, ISSN 2073-4409
Editor: Cell
DOI: 10.1101/196022

A rapid and robust method for single cell chromatin accessibility profiling

Autores: Xi Chen, Kedar Nath Natarajan, Sarah A Teichmann
Publicado en: Nature Communiction, 2018, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1101/309831

Developmental enhancers and chromosome topology

Autores: Eileen E. M. Furlong, Michael Levine
Publicado en: Science, 2018, ISSN 1095-9203
Editor: Science Magazine
DOI: 10.1126/science.aau0320

A Synthetic Oligo Library and Sequencing Approach Reveals an Insulation Mechanism Encoded within Bacterial σ 54 Promoters

Autores: Lior Levy, Leon Anavy, Oz Solomon, Roni Cohen, Michal Brunwasser-Meirom, Shilo Ohayon, Orna Atar, Sarah Goldberg, Zohar Yakhini, Roee Amit
Publicado en: Cell Reports, Edición 21/3, 2017, Página(s) 845-858, ISSN 2211-1247
Editor: Cell Press
DOI: 10.1016/j.celrep.2017.09.063

Genome-wide analysis of fitness data and its application to improve metabolic models

Autores: Edward Vitkin, Oz Solomon, Sharon Sultan, Zohar Yakhini
Publicado en: BMC Bioinformatics, Edición 19/1, 2018, ISSN 1471-2105
Editor: BioMed Central
DOI: 10.1186/s12859-018-2341-9

Using synthetic bacterial enhancers to reveal a looping-based mechanism for quenching-like repression

Autores: Michal Brunwasser-Meirom, Yaroslav Pollak, Sarah Goldberg, Lior Levy, Orna Atar, Roee Amit
Publicado en: Nature Communications, Edición 7, 2016, Página(s) 10407, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/ncomms10407

A Looping-Based Model for Quenching Repression

Autores: Yaroslav Pollak, Sarah Goldberg, Roee Amit
Publicado en: PLOS, 2017
Editor: plos.org
DOI: 10.1371/journal.pcbi.1005337

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