Massive Reverse Genomics to Decipher Gene Regulatory Grammar

Project Information

MRG-GRammar

Grant agreement ID: 664918

DOI 10.3030/664918

Project closed

EC signature date 31 May 2015

Start date 1 August 2015

End date 31 July 2018

Funded under

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Total cost € 3 999 661,00

EU contribution € 3 999 661,00

Coordinated by

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Israel

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Other (1)

Website

Project website for visibility, raising awareness and dissemination purposes. The website will be maintained throughout the execution and will stay alive at least 2 years after the project end.

Documents, reports (4)

Unnatural enhancer data-set and report

Natural enhancer data-set and report

Bottom-up data-set report

Top-down data-set report

Publications

Peer reviewed articles (8)

The interaction landscape between transcription factors and the nucleosome

Author(s): Fangjie Zhu, Lucas Farnung, Eevi Kaasinen, Biswajyoti Sahu, Yimeng Yin, Bei Wei, Svetlana Dodonova, Patrick Cramer, Jussi Taipale
Published in: Nature, 2017, ISSN 2520-1158
Publisher: Nature
DOI: 10.1101/240598

Gene expression variability across cells and species shapes innate immunity

Author(s): Tzachi Hagai, Xi Chen, Ricardo J. Miragaia, Tomas Gomes, Raghd Rostom, Natalia Kunowska, Valentina Proserpio, Giacomo Donati, Lara Bossini-Castillo, Guy Naamati, Guy Emerton, Gosia Trynka, Ivanela Kondova, Mike Denis, Sarah A Teichmann
Published in: Nature, 2017, ISSN 2520-1158
Publisher: Nature
DOI: 10.1101/137992

Genome-wide CRISPR screens in T helper cells reveal pervasive cross-talk between activation and differentiation

Author(s): Johan Henriksson, Xi Chen, Tomás Gomes, Ubaid Ullah, Kerstin B Meyer, Ricardo Miragaia, Graham Duddy, Jhuma Pramanik, Kosuke Yusa, Riita Lahesmaa, Sarah A. Teichmann
Published in: Cell, 2017, ISSN 2073-4409
Publisher: Cell
DOI: 10.1101/196022

A rapid and robust method for single cell chromatin accessibility profiling

Author(s): Xi Chen, Kedar Nath Natarajan, Sarah A Teichmann
Published in: Nature Communiction, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1101/309831

Developmental enhancers and chromosome topology

Author(s): Eileen E. M. Furlong, Michael Levine
Published in: Science, 2018, ISSN 1095-9203
Publisher: Science Magazine
DOI: 10.1126/science.aau0320

A Synthetic Oligo Library and Sequencing Approach Reveals an Insulation Mechanism Encoded within Bacterial σ 54 Promoters

Author(s): Lior Levy, Leon Anavy, Oz Solomon, Roni Cohen, Michal Brunwasser-Meirom, Shilo Ohayon, Orna Atar, Sarah Goldberg, Zohar Yakhini, Roee Amit
Published in: Cell Reports, Issue 21/3, 2017, Page(s) 845-858, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2017.09.063

Genome-wide analysis of fitness data and its application to improve metabolic models

Author(s): Edward Vitkin, Oz Solomon, Sharon Sultan, Zohar Yakhini
Published in: BMC Bioinformatics, Issue 19/1, 2018, ISSN 1471-2105
Publisher: BioMed Central
DOI: 10.1186/s12859-018-2341-9

Using synthetic bacterial enhancers to reveal a looping-based mechanism for quenching-like repression

Author(s): Michal Brunwasser-Meirom, Yaroslav Pollak, Sarah Goldberg, Lior Levy, Orna Atar, Roee Amit
Published in: Nature Communications, Issue 7, 2016, Page(s) 10407, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/ncomms10407

Other (1)

A Looping-Based Model for Quenching Repression

Author(s): Yaroslav Pollak, Sarah Goldberg, Roee Amit
Published in: PLOS, 2017
Publisher: plos.org
DOI: 10.1371/journal.pcbi.1005337