Skip to main content
European Commission logo
Deutsch Deutsch
CORDIS - Forschungsergebnisse der EU
CORDIS
CORDIS Web 30th anniversary CORDIS Web 30th anniversary
Inhalt archiviert am 2024-06-17

Scavidin: a fusion gene for the treatment of cancer

Ziel

The main objective of the proposal is to develop a new target-specific delivery system for the treatment of malignant glioma. For that purpose we have cloned a new fusion gene "Cave-in" which contains intracellular and membrane-spanning domains of scavenger receptor legated to avid in which will form the extra cellular domain of the fusion protein. Cave-in will be transfixed to target tissue with local gene therapy via catheter delivery or during surgical operation with adenovirus or pseudotyped retrovirus technology. Targeted treatment is achieved by binding of biotinylated compounds to Cave-in, which will be only expressed in the transfixed tissue.

Aufforderung zur Vorschlagseinreichung

Data not available

Koordinator

UNIVERSITY OF KUOPIO
EU-Beitrag
Keine Daten
Adresse
Savilahdentie 9
1627 KUOPIO
Finnland

Auf der Karte ansehen

Gesamtkosten
Keine Daten

Beteiligte (3)