Numerical modeling of cardiac electrophysiology at the cellular scale

Livrables

A Software Management Plan for the HPC simulation platform μ CARP

Creation of a Software Management Plan for the HPC simulation platform CARP

Linear solver development and performance assessment report

Publication of a report on the development of linear solvers and an assessment of their performance

Publications

A comparison of Algebraic Multigrid Bidomain solvers on hybrid CPU–GPU architectures

Auteurs: Edoardo Centofanti, Simone Scacchi
Publié dans: Computer Methods in Applied Mechanics and Engineering, Numéro 423, 2024, Page(s) 116875, ISSN 0045-7825
Éditeur: Elsevier BV
DOI: 10.1016/j.cma.2024.116875

Explicit stabilized multirate methods for the monodomain model in cardiac electrophysiology

Auteurs: Giacomo Rosilho de Souza, Marcus Grote, Simone Pezzuto, Rolf Krause
Publié dans: ESAIM: Mathematical Modelling and Numerical Analysis, 2024, ISSN 2822-7840
Éditeur: edpsciences
DOI: 10.1051/m2an/2024030

A Review of Healthy and Fibrotic Myocardium Microstructure Modeling and Corresponding Intracardiac Electrograms

Auteurs: Sánchez, J.; Loewe, A.
Publié dans: Frontiers in Physiology, 2022, ISSN 1664-042X
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fphys.2022.908069

Scalable and Robust Dual-Primal Newton–Krylov Deluxe Solvers for Cardiac Electrophysiology with Biophysical Ionic Models

Auteurs: Ngoc Mai Monica Huynh; Luca F. Pavarino; Simone Scacchi
Publié dans: Vietnam Journal of Mathematics, Numéro 50, 2022, ISSN 2305-221X
Éditeur: Springer Science + Business Media
DOI: 10.1007/s10013-022-00576-1

Boundary integral formulation of the cell-by-cell model of cardiac electrophysiology

Auteurs: Giacomo Rosilho de Souza, Rolf Krause, Simone Pezzuto
Publié dans: Engineering Analysis with Boundary Elements, Numéro 158, 2023, Page(s) 239-251, ISSN 0955-7997
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.enganabound.2023.10.021

Characterization of the pace-and-drive capacity of the human sinoatrial node: A 3D in silico study

Auteurs: Antoine Amsaleg; Jorge Sánchez; Ralf Mikut; Axel Loewe
Publié dans: Biophysical Journal, Numéro 121, 2022, Page(s) 4247–4259, ISSN 0006-3495
Éditeur: Biophysical Society
DOI: 10.1016/j.bpj.2022.10.020

Unexpected impairment of INa underpins reentrant arrhythmias in a knock-in swine model of Timothy syndrome

Auteurs: Andreu Porta-Sánchez, Andrea Mazzanti, Carmen Tarifa, Deni Kukavica, Alessandro Trancuccio, Muhammad Mohsin, Elisa Zanfrini, Andrea Perota, Roberto Duchi, Kevin Hernandez-Lopez, Miguel Eduardo Jáuregui-Abularach, Valerio Pergola, Eugenio Fernandez, Rossana Bongianino, Elisa Tavazzani, Patrick Gambelli, Mirella Memmi, Simone Scacchi, Luca F. Pavarino, Piero Colli Franzone, Giovanni Lentini, David
Publié dans: Nature Cardiovascular Research, Numéro 2, 2023, Page(s) 1291-1309, ISSN 2731-0590
Éditeur: Springer Nature
DOI: 10.1038/s44161-023-00393-w

A Survey of General-purpose Polyhedral Compilers

Auteurs: Arun Thangamani, Vincent Loechner, Stéphane Genaud
Publié dans: ACM Transactions on Architecture and Code Optimization, 2024, ISSN 1544-3566
Éditeur: Association for Computing Machinary, Inc.
DOI: 10.1145/3674735

Epicardial Dispersion of Repolarization Promotes the Onset of Reentry in Brugada Syndrome: A Numerical Simulation Study

Auteurs: Simone Scacchi, Piero Colli Franzone, Luca F. Pavarino, Vincenzo Gionti, Cesare Storti
Publié dans: Bulletin of Mathematical Biology, Numéro 85, 2023, ISSN 0092-8240
Éditeur: Academic Press
DOI: 10.1007/s11538-023-01124-9

The openCARP CDEConcept for and implementation of a sustainable collaborativedevelopment environment for research software

Auteurs: Felix Bach, Jochen Klar, Axel Loewe, Jorge Sánchez, Gunnar Seemann, Yung-Lin Huang, Robert Ulrich
Publié dans: Bausteine Forschungsdatenmanagement, Numéro Nr.1, 2022, ISSN 2626-7489
Éditeur: Marburg: Philipps-Universität
DOI: 10.17192/bfdm.2022.1.8368

À quoi servent les ordinateurs les plus puissants au monde ? Un exemple en cardiologie.

Auteurs: Emmanuelle Saillard; Mark Potse
Publié dans: The Conversation, 2022, ISSN 2431-2134
Éditeur: The Conversation Media Group

The role of pulse timing in cardiac defibrillation

Auteurs: Joshua Steyer, Thomas Lilienkamp, Stefan Luther, Ulrich Parlitz
Publié dans: Frontiers in Network Physiology, Numéro 2, 2023, ISSN 2674-0109
Éditeur: Frontiers
DOI: 10.3389/fnetp.2022.1007585

Attractor selection in nonlinear oscillators by temporary dual-frequency driving

Auteurs: Péter Krähling, Joshua Steyer, Ulrich Parlitz, Ferenc Hegedűs
Publié dans: Nonlinear Dynamics, Numéro 111, 2024, Page(s) 19209-19224, ISSN 0924-090X
Éditeur: Kluwer Academic Publishers
DOI: 10.1007/s11071-023-08855-3

Evaluating computational efforts and physiological resolution of mathematical models of cardiac tissue

Auteurs: Karoline Horgmo Jæger, James D. Trotter, Xing Cai, Hermenegild Arevalo, Aslak Tveito
Publié dans: Scientific Reports, Numéro 14, 2024, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-024-67431-w

Editorial: Atrial Fibrillation: Technology for Diagnosis, Monitoring, and Treatment

Auteurs: Omer Berenfeld, Valentina D. A. Corino, Axel Loewe, Juan Pablo Martínez and Jose F. Rodriguez Matas
Publié dans: Frontiers in Physiology, 2022, ISSN 1664-042X
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fphys.2022.848096

Resource-Efficient Use of Modern Processor Architectures For Numerically Solving Cardiac Ionic Cell Models

Auteurs: Kristian Gregorius Hustad; Xing Cai
Publié dans: Frontiers in Physiology, 2022, ISSN 1664-042X
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fphys.2022.904648

Convergence Analysis of BDDC Preconditioners for Composite DG Discretizations of the Cardiac Cell-By-Cell Model

Auteurs: Ngoc Mai Monica Huynh, Fatemeh Chegini, Luca Franco Pavarino, Martin Weiser, Simone Scacchi
Publié dans: SIAM Journal on Scientific Computing, Numéro 45, 2023, Page(s) A2836-A2857, ISSN 1064-8275
Éditeur: Society for Industrial and Applied Mathematics
DOI: 10.1137/22m1542532

Fibrotic Remodeling during Persistent Atrial Fibrillation: In Silico Investigation of the Role of Calcium for Human Atrial Myofibroblast Electrophysiology

Auteurs: Jorge Sánchez , Beatriz Trenor, Javier Saiz, Olaf Dössel and Axel Loewe
Publié dans: Cells, Numéro 10, 2021, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells10112852

Parallel nonlinear solvers in computational cardiac electrophysiology

Auteurs: Nicolas Alejandro BARNAFI; Ngoc Mai Monica HUYNH; Luca Franco PAVARINO; Simone SCACCHI
Publié dans: IFAC-PapersOnLine, 2022
Éditeur: Elsevier
DOI: 10.1016/j.ifacol.2022.09.093

Combining Uncore Frequency and Dynamic Power Capping to Improve Power Savings

Auteurs: Amina Guermouche
Publié dans: 2022 IEEE International Parallel and Distributed Processing Symposium Workshops (IPDPSW), 2022, ISBN 978-1-6654-9748-0
Éditeur: IEEE
DOI: 10.1109/ipdpsw55747.2022.00164

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