SCIENTIA-FELLOWS II: International Postdoctoral Fellowship Programme

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

3rd call: communication link to Euraxess

Information to the Project Officer about the call publication and a screenshot of call announcement

1st call: communication link to Euroaxess

Information to the Project Officer about the call publication and a screenshot of call announcement

2nd call: communication link to Euroaxess

Information to the Project Officer about the call publication and a screenshot of call announcement

Pubblicazioni

How CAR T Cells Breathe

Autori: Christopher Forcados, Sandy Joaquina, Nicholas Paul Casey, Benjamin Caulier, Sébastien Wälchli
Pubblicato in: Cells, Numero 11, 2025, Pagina/e 1454, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells11091454

Human cytomegalovirus infection perturbs neural progenitor cell fate via the expression of viral microRNAs

Autori: Xuan Jiang, Siqing Liu, Ya‐Ru Fu, Xi‐Juan Liu, Xiao‐Jun Li, Bo Yang, Hai‐Fei Jiang, Zhang‐Zhou Shen, Endalkachew Ashenafi Alemu, Pavel Vazquez, Yaping Tang, Mari Kaarbø, Michael A. McVoy, Simon Rayner, Min‐Hua Luo
Pubblicato in: Journal of Medical Virology, Numero 95, 2024, ISSN 0146-6615
Editore: John Wiley & Sons Inc.
DOI: 10.1002/jmv.28574

Colorimetric and Electrochemical Screening for Early Detection of Diabetes Mellitus and Diabetic Retinopathy—Application of Sensor Arrays and Machine Learning

Autori: Georgina Faura; Gerard Boix-Lemonche; Anne Kristin Holmeide; Rasa Verkauskiene; Vallo Volke; Jelizaveta Sokolovska; Goran Petrovski
Pubblicato in: Sensors, Numero Vol 22, Iss 718, p 718, 2022, ISSN 1424-8220
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s22030718

Using Polygenic Hazard Scores to Predict Age at Onset of Alzheimer’s Disease in Nordic Populations

Autori: Ehsan Motazedi, Weiqiu Cheng, Jesper Q. Thomassen, Oleksandr Frei, Arvid Rongve, Lavinia Athanasiu, Shahram Bahrami, Alexey Shadrin, Ingun Ulstein, Eystein Stordal, Anne Brækhus, Ingvild Saltvedt, Sigrid B. Sando, Kevin S. O’Connell, Guy Hindley, Dennis van der Meer, Sverre Bergh, Børge G. Nordestgaard, Anne Tybjærg-Hansen, Geir Bråthen, Lasse Pihlstrøm, Srdjan Djurovic, Ruth Frikke-Schmidt
Pubblicato in: Journal of Alzheimer's Disease, Numero 88, 2024, Pagina/e 1533-1544, ISSN 1387-2877
Editore: IOS Press
DOI: 10.3233/jad-220174

Divalent ligand-monovalent molecule binding.

Autori: Mathijs Janssen; Harald Stenmark; Andreas Carlson
Pubblicato in: Soft Matter, 2021, ISSN 1744-683X
Editore: Royal Society of Chemistry
DOI: 10.1039/d1sm00070e

Predictors of early adulthood insomnia following exposure to a single mass violence attack during adolescence: 7–13 year follow-up from the Utøya and HUNT studies

Autori: Kate Porcheret, Grete Dyb, Tore Wentzel-Larsen, Synne Øien Stensland
Pubblicato in: European Journal of Psychotraumatology, Numero 15, 2024, ISSN 2000-8066
Editore: Taylor and Francis
DOI: 10.1080/20008066.2024.2312750

Temporal expression and spatial distribution of the proteoglycan versican during cardiac fibrosis development

Autori: Athiramol Sasi, Andreas Romaine, Pugazendhi Murugan Erusappan, Arne Olav Melleby, Almira Hasic, Christen Peder Dahl, Kaspar Broch, Vibeke Marie Almaas, Rosa Doñate Puertas, H. Llewelyn Roderick, Ida Gjervold Lunde, Ivar Sjaastad, Maria Vistnes, Geir Christensen
Pubblicato in: Matrix Biology Plus, Numero 19-20, 2023, Pagina/e 100135, ISSN 2590-0285
Editore: Elsevier
DOI: 10.1016/j.mbplus.2023.100135

Efficient chimeric antigen receptor targeting of a central epitope of CD22

Autori: Nicholas Paul Casey, Clara Helena Klee, Anne Fåne, Benjamin Caulier, Agnieszka Graczyk-Jarzynka, Marta Krawczyk, Klaudyna Fidyt, Sarah E. Josefsson, Hakan Köksal, Pierre Dillard, Elzbieta Patkowska, Malgorzata Firczuk, Erlend B. Smeland, Magdalena Winiarska, June H. Myklebust, Else Marit Inderberg, Sébastien Wälchli
Pubblicato in: Journal of Biological Chemistry, Numero 299, 2023, Pagina/e 104883, ISSN 0021-9258
Editore: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.jbc.2023.104883

Fipronil affects cockroach behavior and olfactory memory

Autori: Maria Eduarda Rosa, Letícia Campos, Bruna Trindade Borges, Sara Santos, Yuri Correia Barreto, Denis Reis de Assis, Stephen Hyslop, Velci Queiroz de Souza, Lúcia Vinadé, Cháriston André Dal Belo
Pubblicato in: Journal of Experimental Biology, Numero 226, 2023, ISSN 0022-0949
Editore: The Company of Biologists Ltd.
DOI: 10.1242/jeb.245239

Modulation of multidrug-resistant clone success in Escherichia coli populations: a longitudinal, multi-country, genomic and antibiotic usage cohort study

Autori: Anna K Pöntinen, Rebecca A Gladstone, Henri Pesonen, Maiju Pesonen, François Cléon, Benjamin J Parcell, Teemu Kallonen, Gunnar Skov Simonsen, Nicholas J Croucher, Alan McNally, Julian Parkhill, Pål J Johnsen, Ørjan Samuelsen, Jukka Corander
Pubblicato in: The Lancet Microbe, Numero 5, 2024, Pagina/e e142-e150, ISSN 2666-5247
Editore: The Lancet Microbe
DOI: 10.1016/s2666-5247(23)00292-6

Abundant pleiotropy across neuroimaging modalities identified through a multivariate genome-wide association study

Autori: E. P. Tissink, A. A. Shadrin, D. van der Meer, N. Parker, G. Hindley, D. Roelfs, O. Frei, C. C. Fan, M. Nagel, T. Nærland, M. Budisteanu, S. Djurovic, L. T. Westlye, M. P. van den Heuvel, D. Posthuma, T. Kaufmann, A. M. Dale, O. A. Andreassen
Pubblicato in: Nature Communications, Numero 15, 2024, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-024-46817-4

A heavy-tailed model for analyzing miRNA-seq raw read counts

Autori: Annika Krutto, Therese Haugdahl Nøst, Magne Thoresen
Pubblicato in: Statistical Applications in Genetics and Molecular Biology, Numero 23, 2024, ISSN 1544-6115
Editore: Berkeley Electronic Press
DOI: 10.1515/sagmb-2023-0016

Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness

Autori: Weiqiu Cheng, Oleksandr Frei, Dennis van der Meer, Yunpeng Wang, Kevin S. O’Connell, Yunhan Chu, Shahram Bahrami, Alexey A. Shadrin, Dag Alnæs, Guy F. L. Hindley, Aihua Lin, Naz Karadag, Chun-Chieh Fan, Lars T. Westlye, Tobias Kaufmann, Espen Molden, Anders M. Dale, Srdjan Djurovic, Olav B. Smeland, Ole A. Andreassen
Pubblicato in: JAMA Psychiatry, Numero 78/9, 2021, Pagina/e 1020, ISSN 2168-622X
Editore: American Medical Association
DOI: 10.1001/jamapsychiatry.2021.1435

Genetic Overlap Between Global Cortical Brain Structure, C-Reactive Protein, and White Blood Cell Counts

Autori: Nadine Parker, Weiqiu Cheng, Guy F.L. Hindley, Kevin S. O’Connell, Sandeep Karthikeyan, Børge Holen, Alexey A. Shadrin, Zillur Rahman, Naz Karadag, Shahram Bahrami, Aihua Lin, Nils Eiel Steen, Thor Ueland, Pål Aukrust, Srdjan Djurovic, Anders M. Dale, Olav B. Smeland, Oleksandr Frei, Ole A. Andreassen
Pubblicato in: Biological Psychiatry, Numero 95, 2024, Pagina/e 62-71, ISSN 0006-3223
Editore: Elsevier BV
DOI: 10.1016/j.biopsych.2023.06.008

The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics

Autori: Matthew Yoke Wui Ng, Chara Charsou, Ana Lapao, Sakshi Singh, Laura Trachsel-Moncho, Sebastian W. Schultz, Sigve Nakken, Michael J. Munson, Anne Simonsen
Pubblicato in: Nature Communications, Numero 13, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-022-33933-2

Allelic variation of KIR and HLA tunes the cytolytic payload and determines functional hierarchy of NK cell repertoires

Autori: Camille Philippon, Sudan Tao, Dennis Clement, Alvaro Haroun-Izquierdo, Katherine M. Kichula, Herman Netskar, Ludwig Brandt, Vincent Sheng Oei, Minoru Kanaya, Pilar Maria Lanuza, Marie Schaffer, Jodie P. Goodridge, Amir Horowitz, Faming Zhu, Quirin Hammer, Ebba Sohlberg, Rakesh Kumar Majhi, Lise Kveberg, Björn Önfelt, Paul J. Norman, Karl-Johan Malmberg
Pubblicato in: Blood Advances, Numero 7, 2023, Pagina/e 4492-4504, ISSN 2473-9529
Editore: Elsevier
DOI: 10.1182/bloodadvances.2023009827

The population-level impact of Enterococcus faecalis genetics on intestinal colonisation and extraintestinal infection

Autori: Chrispin Chaguza, Anna K. Pöntinen, Janetta Top, Sergio Arredondo-Alonso, Ana R. Freitas, Carla Novais, Carmen Torres, Stephen D. Bentley, Luisa Peixe, Teresa M. Coque, Rob J.L. Willems, Jukka Corander
Pubblicato in: Microbiology Spectrum, 2022, ISSN 2165-0497
Editore: American Society for Microbiology (AsM)
DOI: 10.1101/2022.09.26.509451

Stability of a biomembrane tube covered with proteins

Autori: Mathijs Janssen, Susanne Liese, Sami C. Al-Izzi, Andreas Carlson
Pubblicato in: Physical Review E, Numero 109, 2024, ISSN 2470-0045
Editore: American Physical Society
DOI: 10.1103/physreve.109.044403

rPanglaoDB: an R package to download and merge labeled single-cell RNA-seq data from the PanglaoDB database

Autori: Daniel Osorio, Marieke L Kuijjer, James J Cai
Pubblicato in: Bioinformatics, Numero 38, 2023, Pagina/e 580-582, ISSN 1367-4803
Editore: Oxford University Press
DOI: 10.1093/bioinformatics/btab549

Intracorneal Implantation of 3D Bioprinted Scaffolds Containing Mesenchymal Stromal Cells Using Femtosecond‐Laser‐Assisted Intrastromal Keratoplasty

Autori: Gerard Boix‐Lemonche; Richard M. Nagymihaly; Essi M. Niemi; Natasha Josifovska; Stian Johansen; Morten C. Moe; Hanne Scholz; Goran Petrovski
Pubblicato in: Macromolecular Bioscience, 2023, ISSN 1616-5195
Editore: Wiley-VCH GmbH
DOI: 10.1002/mabi.202200422

CELLULAR, A Cell Autophagy Imaging Dataset

Autori: Amani Al Outa, Steven Hicks, Vajira Thambawita, Siri Andresen, Jorrit M. Enserink, Pål Halvorsen, Michael A. Riegler, Helene Knævelsrud
Pubblicato in: Scientific Data, Numero 10, 2023, ISSN 2052-4463
Editore: Nature
DOI: 10.1038/s41597-023-02687-x

The human lens is capable of trilineage differentiation towards osteo-, chondro-, and adipogenesis—a model for studying cataract pathogenesis

Autori: Boix-Lemonche, Gerard; Nagymihaly, Richard M.; Lumi, Xhevat; Petrovski, Goran
Pubblicato in: Frontiers in Bioengineering and Biotechnology, 2023, ISSN 2296-4185
Editore: Frontiers Media S.A.
DOI: 10.3389/fbioe.2023.1164795

Pangenome-spanning epistasis and coselection analysis via de Bruijn graphs

Autori: Juri Kuronen, Samuel T. Horsfield, Anna K. Pöntinen, Sudaraka Mallawaarachchi, Sergio Arredondo-Alonso, Harry Thorpe, Rebecca A. Gladstone, Rob J.L. Willems, Stephen D. Bentley, Nicholas J. Croucher, Johan Pensar, John A. Lees, Gerry Tonkin-Hill, Jukka Corander
Pubblicato in: Genome Research, Numero 34, 2024, Pagina/e 1081-1088, ISSN 1088-9051
Editore: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gr.278485.123

Piezo1 activation by stretching of uterine myometrium supports pregnancy and prevents preterm labour

Autori: Rakesh Kumar Majhi, Shirin Pourteymour
Pubblicato in: The Journal of Physiology, Numero 601, 2023, Pagina/e 719-721, ISSN 0022-3751
Editore: Blackwell Publishing Inc.
DOI: 10.1113/jp283810

Determination of CAR T cell metabolism in an optimized protocol

Autori: Sandy Joaquina; Christopher Forcados; Benjamin Caulier; Benjamin Caulier; Benjamin Caulier; Else Marit Inderberg; Sébastien Wälchli
Pubblicato in: Frontiers in Bioengineering and Biotechnology, Vol 11 (2023), Numero 2, 2023, ISSN 2296-4185
Editore: Frontiers Media SA
DOI: 10.3389/fbioe.2023.1207576

Stable and locally mass- and momentum-conservative control-volume finite-element schemes for the Stokes problem

Autori: Martin Schneider, Timo Koch
Pubblicato in: Computer Methods in Applied Mechanics and Engineering, Numero 420, 2024, Pagina/e 116723, ISSN 0045-7825
Editore: Elsevier BV
DOI: 10.1016/j.cma.2023.116723

CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia

Autori: Benjamin Caulier, Sandy Joaquina, Pascal Gelebart, Tara Helén Dowling, Fatemeh Kaveh, Moritz Thomas, Luka Tandaric, Patrik Wernhoff, Niveditha Umesh Katyayini, Cara Wogsland, May Eriksen Gjerstad, Yngvar Fløisand, Gunnar Kvalheim, Carsten Marr, Sebastian Kobold, Jorrit M. Enserink, Bjørn Tore Gjertsen, Emmet McCormack, Else Marit Inderberg, Sébastien Wälchli
Pubblicato in: Cell Reports Medicine, Numero 5, 2024, Pagina/e 101572, ISSN 2666-3791
Editore: Cell Press
DOI: 10.1016/j.xcrm.2024.101572

Thermoplastic Elastomer (TPE)–Poly(Methyl Methacrylate) (PMMA) Hybrid Devices for Active Pumping PDMS-Free Organ-on-a-Chip Systems

Autori: Mathias Busek, Steffen Nøvik, Aleksandra Aizenshtadt, Mikel Amirola-Martinez, Thomas Combriat, Stefan Grünzner, Stefan Krauss
Pubblicato in: Biosensors, Numero 11/5, 2021, Pagina/e 162, ISSN 2079-6374
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios11050162

Pump-less, recirculating organ-on-a-chip (rOoC) platform

Autori: M. Busek; A. Aizenshtadt; T. Koch; A. Frank; L. Delon; M. Amirola Martinez; A. Golovin; C. Dumas; J. Stokowiec; S. Gruenzner; E. Melum; S. Krauss
Pubblicato in: Lab on a Chip, 2023, ISSN 1473-0197
Editore: Royal Society of Chemistry
DOI: 10.1039/d2lc00919f

Psychiatric disorders and brain white matter exhibit genetic overlap implicating developmental and neural cell biology

Autori: Nadine Parker, Weiqiu Cheng, Guy F. L. Hindley, Pravesh Parekh, Alexey A. Shadrin, Ivan I. Maximov, Olav B. Smeland, Srdjan Djurovic, Anders M. Dale, Lars T. Westlye, Oleksandr Frei, Ole A. Andreassen
Pubblicato in: Molecular Psychiatry, Numero 28, 2024, Pagina/e 4924-4932, ISSN 1359-4184
Editore: Nature Publishing Group
DOI: 10.1038/s41380-023-02264-z

The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study

Autori: Weiqiu Cheng, Nadine Parker, Naz Karadag, Elise Koch, Guy Hindley, Romain Icick, Alexey Shadrin, Kevin S O’Connell, Thomas Bjella, Shahram Bahrami, Zillur Rahman, Markos Tesfaye, Piotr Jaholkowski, Linn Rødevand, Børge Holen, Trine Vik Lagerberg, Nils Eiel Steen, Srdjan Djurovic, Anders M Dale, Oleksandr Frei, Olav B Smeland, Ole A Andreassen
Pubblicato in: The Lancet Psychiatry, Numero 10, 2024, Pagina/e 441-451, ISSN 2215-0366
Editore: Elsevier Limited
DOI: 10.1016/s2215-0366(23)00143-8

Transcriptional and functional effects of lithium in bipolar disorder iPSC-derived cortical spheroids

Autori: Jordi Requena Osete, Ibrahim A. Akkouh, Oleksandr Ievglevskyi, Matthieu Vandenberghe, Denis Reis de Assis, Thor Ueland, Elena Kondratskaya, Børge Holen, Attila Szabo, Timothy Hughes, Olav B. Smeland, Vidar Martin Steen, Ole A. Andreassen, Srdjan Djurovic
Pubblicato in: Molecular Psychiatry, Numero 28, 2023, Pagina/e 3033-3043, ISSN 1359-4184
Editore: Nature Publishing Group
DOI: 10.1038/s41380-023-01944-0

Identification of trypsin-degrading commensals in the large intestine

Autori: Youxian Li, Eiichiro Watanabe, Yusuke Kawashima, Damian R. Plichta, Zhujun Wang, Makoto Ujike, Qi Yan Ang, Runrun Wu, Munehiro Furuichi, Kozue Takeshita, Koji Yoshida, Keita Nishiyama, Sean M. Kearney, Wataru Suda, Masahira Hattori, Satoshi Sasajima, Takahiro Matsunaga, Xiaoxi Zhang, Kazuto Watanabe, Jun Fujishiro, Jason M. Norman, Bernat Olle, Shutoku Matsuyama, Ho Namkoong, Yoshifumi Uwamino, Ma
Pubblicato in: Nature, Numero 609, 2022, Pagina/e 582-589, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-022-05181-3

Detecting co-selection through excess linkage disequilibrium in bacterial genomes

Autori: Sudaraka Mallawaarachchi, Gerry Tonkin-Hill, Anna K Pöntinen, Jessica K Calland, Rebecca A Gladstone, Sergio Arredondo-Alonso, Neil MacAlasdair, Harry A Thorpe, Janetta Top, Samuel K Sheppard, David Balding, Nicholas J Croucher, Jukka Corander
Pubblicato in: NAR Genomics and Bioinformatics, Numero 6, 2024, ISSN 2631-9268
Editore: Oxford University Press
DOI: 10.1093/nargab/lqae061

A comprehensive <scp>AI</scp>‐driven analysis of large‐scale omic datasets reveals novel dual‐purpose targets for the treatment of cancer and aging

Autori: Frank W. Pun, Geoffrey Ho Duen Leung, Hoi Wing Leung, Jared Rice, Tomas Schmauck‐Medina, Sofie Lautrup, Xi Long, Bonnie Hei Man Liu, Chun Wai Wong, Ivan V. Ozerov, Alex Aliper, Feng Ren, Ari J. Rosenberg, Nishant Agrawal, Evgeny Izumchenko, Evandro F. Fang, Alex Zhavoronkov
Pubblicato in: Aging Cell, Numero 22, 2024, ISSN 1474-9718
Editore: Blackwell Publishing Inc.
DOI: 10.1111/acel.14017

Deciphering the Retinal Epigenome during Development, Disease and Reprogramming: Advancements, Challenges and Perspectives

Autori: Cristina Zibetti
Pubblicato in: Cells, Numero 11, 2024, Pagina/e 806, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells11050806

V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis

Autori: Miriam Formica, Alessandra Maria Storaci, Irene Bertolini, Francesca Carminati, Helene Knævelsrud, Valentina Vaira, Thomas Vaccari
Pubblicato in: Autophagy, Numero 17, 2021, Pagina/e 4442-4452, ISSN 1554-8627
Editore: Landes Bioscience
DOI: 10.1080/15548627.2021.1918915

Evolutionary and functional history of the Escherichia coli K1 capsule

Autori: Sergio Arredondo-Alonso, George Blundell-Hunter, Zuyi Fu, Rebecca A. Gladstone, Alfred Fillol-Salom, Jessica Loraine, Elaine Cloutman-Green, Pål J. Johnsen, Ørjan Samuelsen, Anna K. Pöntinen, François Cléon, Susana Chavez-Bueno, Miguel A. De la Cruz, Miguel A. Ares, Manivanh Vongsouvath, Agnieszka Chmielarczyk, Carolyne Horner, Nigel Klein, Alan McNally, Joice N. Reis, José R. Penadés, Nich
Pubblicato in: nature communications, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-023-39052-w

GAK and PRKCD are positive regulators of PRKN-independent mitophagy

Autori: Michael J. Munson, Benan J. Mathai, Matthew Yoke Wui Ng, Laura Trachsel-Moncho, Laura R. de la Ballina, Sebastian W. Schultz, Yahyah Aman, Alf H. Lystad, Sakshi Singh, Sachin Singh, Jørgen Wesche, Evandro F. Fang, Anne Simonsen
Pubblicato in: Nature Communications, Numero 12/1, 2021, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-021-26331-7

Estimating the Logarithm of Characteristic Function and Stability Parameter for Symmetric Stable Laws

Autori: Jüri Lember; Annika Krutto
Pubblicato in: Methodology and Computing in Applied Probability, 2021, ISSN 1387-5841
Editore: Kluwer Academic Publishers
DOI: 10.1007/s11009-021-09908-z

Pharmacologic Control of CAR T Cells.

Autori: Benjamin Caulier; Jorrit M. Enserink; Sébastien Wälchli
Pubblicato in: International Journal of Molecular Sciences, 2021, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22094320

Longitudinal tracking of acute kidney injury reveals injury propagation along the nephron

Autori: Luca Bordoni, Anders Kristensen, Donato Sardella, Hanne Kidmose, Layla Pohl, Søren Krag, Ina Maria Schiessl
Pubblicato in: Nature Communications, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.21203/rs.3.rs-2487613/v1

Unraveling the shared genetics of common epilepsies and general cognitive ability

Autori: Naz Karadag, Espen Hagen, Alexey A. Shadrin, Dennis van der Meer, Kevin S. O'Connell, Zillur Rahman, Gleda Kutrolli, Nadine Parker, Shahram Bahrami, Vera Fominykh, Kjell Heuser, Erik Taubøll, Torill Ueland, Nils Eiel Steen, Srdjan Djurovic, Anders M. Dale, Oleksandr Frei, Ole A. Andreassen, Olav B. Smeland
Pubblicato in: Seizure: European Journal of Epilepsy, Numero 122, 2024, Pagina/e 105-112, ISSN 1059-1311
Editore: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.seizure.2024.09.016

The crystal structure of mycothiol disulfide reductase (Mtr) provides mechanistic insight into the specific low-molecular-weight thiol reductase activity of Actinobacteria

Autori: Javier Gutiérrez-Fernández, Hans-Petter Hersleth, Marta Hammerstad
Pubblicato in: Acta Crystallographica Section D Structural Biology, Numero 80, 2025, Pagina/e 181-193, ISSN 2059-7983
Editore: IUCr
DOI: 10.1107/s205979832400113x

Single-Cell Transcriptomic Profiling of Cholangiocyte Organoids Derived from Bile Ducts of Primary Sclerosing Cholangitis Patients

Autori: Anna Katharina Frank, Brian K. Chung, Miguel Larraz Lopez De Novales, Lise Katrine Engesæter, Henry William Hoyle, Jonas Øgaard, James Heslop, Tom H. Karlsen, Olivia Tysoe, Teresa Brevini, Jan S. Tchorz, Ludovic Vallier, Irina Mohorianu, Fotios Sampaziotis, Espen Melum
Pubblicato in: Digestive Diseases and Sciences, Numero 69, 2024, Pagina/e 3810-3823, ISSN 0163-2116
Editore: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s10620-024-08570-y

Population-level comparisons of gene regulatory networks modeled on high-throughput single-cell transcriptomics data

Autori: Daniel Osorio, Anna Capasso, S. Gail Eckhardt, Uma Giri, Alexander Somma, Todd M. Pitts, Christopher H. Lieu, Wells A. Messersmith, Stacey M. Bagby, Harinder Singh, Jishnu Das, Nidhi Sahni, S. Stephen Yi, Marieke L. Kuijjer
Pubblicato in: Nature Computational Science, 2024, ISSN 2662-8457
Editore: Nature
DOI: 10.1101/2023.01.20.524974

Robust monolithic solvers for the Stokes-Darcy problem with the Darcy equation in primal form

Autori: Wietse M. Boon; Timo Koch; Miroslav Kuchta; Kent-André Mardal
Pubblicato in: SIAM Journal on Scientific Computing, 2022, ISSN 1064-8275
Editore: Society for Industrial and Applied Mathematics
DOI: 10.1137/21m1452974

Mge-cluster: a reference-free approach for typing bacterial plasmids

Autori: Sergio Arredondo-Alonso, Rebecca A Gladstone, Anna K Pöntinen, João A Gama, Anita C Schürch, Val F Lanza, Pål Jarle Johnsen, Ørjan Samuelsen, Gerry Tonkin-Hill, Jukka Corander
Pubblicato in: NAR Genomics and Bioinformatics, 2023, ISSN 2631-9268
Editore: Oxford University Press
DOI: 10.1093/nargab/lqad066

<scp>FEMA</scp>: Fast and efficient mixed‐effects algorithm for large sample whole‐brain imaging data

Autori: Pravesh Parekh, Chun Chieh Fan, Oleksandr Frei, Clare E. Palmer, Diana M. Smith, Carolina Makowski, John R. Iversen, Diliana Pecheva, Dominic Holland, Robert Loughnan, Pierre Nedelec, Wesley K. Thompson, Donald J. Hagler, Ole A. Andreassen, Terry L. Jernigan, Thomas E. Nichols, Anders M. Dale
Pubblicato in: Human Brain Mapping, Numero 45, 2024, ISSN 1065-9471
Editore: John Wiley & Sons Inc.
DOI: 10.1002/hbm.26579

Recovering Escherichia coli Plasmids in the Absence of Long-Read Sequencing Data

Autori: Julian A. Paganini, Nienke L. Plantinga, Sergio Arredondo-Alonso, Rob J. L. Willems, Anita C. Schürch
Pubblicato in: Microorganisms, Numero 9/8, 2021, Pagina/e 1613, ISSN 2076-2607
Editore: MDPI
DOI: 10.3390/microorganisms9081613

Charting the shared genetic architecture of Alzheimer's disease, cognition, and educational attainment, and associations with brain development

Autori: Piotr Jaholkowski, Shahram Bahrami, Vera Fominykh, Guy F.L. Hindley, Markos Tesfaye, Pravesh Parekh, Nadine Parker, Tahir T. Filiz, Kaja Nordengen, Espen Hagen, Elise Koch, Nora R. Bakken, Evgeniia Frei, Viktoria Birkenæs, Zillur Rahman, Oleksandr Frei, Jan Haavik, Srdjan Djurovic, Anders M. Dale, Olav B. Smeland, Kevin S. O’Connell, Alexey A. Shadrin, Ole A. Andreassen
Pubblicato in: Neurobiology of Disease, Numero 203, 2025, Pagina/e 106750, ISSN 0969-9961
Editore: Academic Press
DOI: 10.1016/j.nbd.2024.106750

Collaborative benchmarking of functional-structural root architecture models: Quantitative comparison of simulated root water uptake

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A (Dual) Network Model for Heat Transfer in Porous Media

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Nonlinear mixed-dimension model for embedded tubular networks with application to root water uptake

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Photoannealing of Microtissues Creates High‐Density Capillary Network Containing Living Matter in a Volumetric‐Independent Manner

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User-View on Organ-on-a-Chip Technology

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Robust analysis of prokaryotic pangenome gene gain and loss rates with Panstripe

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The Effects of the Coating and Aging of Biodegradable Polylactic Acid Membranes on In Vitro Primary Human Retinal Pigment Epithelium Cells

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WRN loss accelerates abnormal adipocyte metabolism in Werner syndrome

Autori: Yuyao Tian, Sofie Lautrup, Patrick Wai Nok Law, Ngoc-Duy Dinh, Evandro Fei Fang, Wai-Yee Chan
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Shared genetic architecture between schizophrenia and subcortical brain volumes implicates early neurodevelopmental processes and brain development in childhood

Autori: Cheng, Weiqiu; van der Meer, Dennis; Parker, Nadine; Hindley, Guy Frederick Lanyon; O'Connell, Kevin Sean; Wang, Yunpeng; Shadrin, Alexey; Alnæs, Dag; Bahrami, Shahram; Lin, Aihua; Karadag, Naz; Holen, Børge; Fernández-Cabello, Sara; Fan, Chun-Chieh; Dale, Anders; Djurovic, Srdjan; Westlye, Lars Tjelta; Frei, Oleksandr; Smeland, Olav Bjerkehagen; Andreassen, Ole
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Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation

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Reversible heat production during electric double layer buildup depends sensitively on the electrolyte and its reservoir

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Genome-wide Association Analysis of Schizophrenia and Vitamin D Levels Shows Shared Genetic Architecture and Identifies Novel Risk Loci

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Bacterial Toxin-Triggered Release of Antibiotics from Capsosomes Protects a Fly Model from Lethal Methicillin-Resistant Staphylococcus aureus (MRSA) Infection

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Detecting co-selection through excess linkage disequilibrium in bacterial genomes

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Modulation of in Vitro SARS-CoV-2 Infection by Stephania tetrandra and Its Alkaloid Constituents

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Seizing the moment: Zebrafish epilepsy models

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Crowding-Regulated Binding of Divalent Biomolecules

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Omega-3 fatty acids and individual variability in plasma triglyceride response: A mini-review

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Retinal Pigment Epithelium Cell Development: Extrapolating Basic Biology to Stem Cell Research

Autori: Santosh Gupta; Lyubomyr Lytvynchuk; Taras Ardan; Hana Studenovska; Georgina Faura; Lars Eide; Ljubo Znaor; Slaven Erceg; Knut Stieger; Jan Motlik; Kapil Bharti; Goran Petrovski
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The G Protein–Coupled Receptor GPR56 Is an Inhibitory Checkpoint for NK Cell Migration

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Spontaneous Formation of Prebiotic Compartment Colonies on Hadean Earth and Pre-Noachian Mars

Autori: Köksal, Elif; Põldsalu, Inga; Friis, Henrik; Mojzsis, Stephen J; Bizzarro, Martin; Gözen, Irep
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Quantitative analysis of neuronal mitochondrial movement reveals patterns resulting from neurotoxicity of rotenone and 6-hydroxydopamine

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WRN promotes bone development and growth by unwinding SHOX-G-quadruplexes via its helicase activity in Werner Syndrome

Autori: Yuyao Tian, Wuming Wang, Sofie Lautrup, Hui Zhao, Xiang Li, Patrick Wai Nok Law, Ngoc-Duy Dinh, Evandro Fei Fang, Hoi Hung Cheung, Wai-Yee Chan
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Transmission Line Circuit and Equation for an Electrolyte-Filled Pore of Finite Length

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Childhood trajectories of emotional and behavioral difficulties are related to polygenic liability for mood and anxiety disorders

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Contrast-enhanced Micro-CT 3D visualization of cell distribution in hydrated human cornea

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Characterizing the polygenic overlap and shared loci between rheumatoid arthritis and cardiovascular diseases

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Apparent nosocomial adaptation of Enterococcus faecalis predates the modern hospital era

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Identification of novel genomic loci for anxiety symptoms and extensive genetic overlap with psychiatric disorders

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Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution

Autori: Eva S. Cunha, Xiaorui Chen, Marta Sanz-Gaitero, Deryck J. Mills, Hartmut Luecke
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GridFormat: header-only C++-library for grid fileI/O

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Targeting shelterin proteins for cancer therapy

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Energy metabolism in skeletal muscle cells from donors with different body mass index

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Emergence and dissemination of antimicrobial resistance in Escherichia coli causing bloodstream infections in Norway in 2002–17: a nationwide, longitudinal, microbial population genomic study

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The population-level impact of Enterococcus faecalis genetics on intestinal colonization and extraintestinal infection

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Regulatory Network of PD1 Signaling Is Associated with Prognosis in Glioblastoma Multiforme

Autori: Camila M. Lopes-Ramos; Tatiana Belova; Tess H. Brunner; Marouen Ben Guebila; Daniel Osorio; John Quackenbush; Marieke L. Kuijjer; Marieke L. Kuijjer
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Roles of NAD+in Health and Aging

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Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy

Autori: Guy Hindley, Alexey A. Shadrin, Dennis van der Meer, Nadine Parker, Weiqiu Cheng, Kevin S. O’Connell, Shahram Bahrami, Aihua Lin, Naz Karadag, Børge Holen, Thomas Bjella, Ian J. Deary, Gail Davies, W. David Hill, Jan Bressler, Sudha Seshadri, Chun Chieh Fan, Torill Ueland, Srdjan Djurovic, Olav B. Smeland, Oleksandr Frei, Anders M. Dale, Ole A. Andreassen
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Mice lacking intestinal Nr1i2 have normal intestinal homeostasis under steady‐state conditions and are not hypersensitive to inflammation under lipopolysaccharide treatment

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Using iPSC Models to Understand the Role of Estrogen in Neuron-Glia Interactions in Schizophrenia and Bipolar Disorder.

Autori: Denis Reis de Assis; Attila Szabo; Jordi Requena Osete; Francesca Puppo; Kevin S. O’Connell; Ibrahim A. Akkouh; Timothy P. Hughes; Evgeniia Frei; Ole A. Andreassen; Srdjan Djurovic
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Academic User View: Organ-on-a-Chip Technology

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Distinct biological signature and modifiable risk factors underlie the comorbidity between major depressive disorder and cardiovascular disease

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Perinatal exposure to potential endocrine disrupting chemicals and autism spectrum disorder: From Norwegian birth cohort to zebrafish studies

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Krill oil supplementation in vivo promotes increased fuel metabolism and protein synthesis in cultured human skeletal muscle cells

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Making sustainable healthcare decisions: three turns towards sustainable guidelines

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Estimates for the astrocyte endfoot sheath permeability of the extra-cellular pathway

Autori: Timo Koch; Vegard Vinje; Kent-André Mardal
Pubblicato in: Fluids and Barriers of the CNS, 2023, ISSN 2045-8118
Editore: BioMed Central
DOI: 10.1186/s12987-023-00421-8

Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders

Autori: Guy Hindley, Ole Kristian Drange, Aihua Lin, Gleda Kutrolli, Alexey A. Shadrin, Nadine Parker, Kevin S. O’Connell, Linn Rødevand, Weiqiu Cheng, Shahram Bahrami, Naz Karadag, Børge Holen, Piotr Jaholkowski, Markos Tesfaye Woldeyohannes, Srdjan Djurovic, Anders M. Dale, Oleksandr Frei, Thor Ueland, Olav B. Smeland, Ole A. Andreassen
Pubblicato in: Psychoneuroendocrinology, Numero 157, 2024, Pagina/e 106368, ISSN 0306-4530
Editore: Pergamon Press
DOI: 10.1016/j.psyneuen.2023.106368

Dynamic density functional theory for the charging of electric double layer capacitors

Autori: Ma, Ke Janssen, Mathijs Adriaan Lian, Cheng Van Roij, René
Pubblicato in: Journal of Chemical Physics, 2022, ISSN 0021-9606
Editore: American Institute of Physics
DOI: 10.1063/5.0081827

Improved functional mapping of complex trait heritability with GSA-MiXeR implicates biologically specific gene sets

Autori: Oleksandr Frei, Guy Hindley, Alexey A. Shadrin, Dennis van der Meer, Bayram C. Akdeniz, Espen Hagen, Weiqiu Cheng, Kevin S. O’Connell, Shahram Bahrami, Nadine Parker, Olav B. Smeland, Dominic Holland, null null, Christiaan de Leeuw, Danielle Posthuma, Ole A. Andreassen, Anders M. Dale
Pubblicato in: Nature Genetics, Numero 56, 2024, Pagina/e 1310-1318, ISSN 1061-4036
Editore: Nature Publishing Group
DOI: 10.1038/s41588-024-01771-1

Protocells: Milestones and Recent Advances

Autori: Irep Gözen; Elif Senem Köksal; Inga Põldsalu; Lin Xue; Karolina Spustova; Esteban Pedrueza‐Villalmanzo; Ruslan Ryskulov; Fanda Meng; Aldo Jesorka
Pubblicato in: Small, 2022, ISSN 1613-6829
Editore: Wiley-VCH GmbH
DOI: 10.1002/smll.202106624

fieldcompare: A Python package for regression testing simulation results

Autori: Dennis Gläser; Timo Koch; Sören Peters; Sven Marcus; Bernd Flemisch
Pubblicato in: Journal of Open Source Software, 2023, ISSN 2475-9066
Editore: Journal of Open Source Software
DOI: 10.21105/joss.04905

NLRP3 inflammasome mediates astroglial dysregulation of innate and adaptive immune responses in schizophrenia

Autori: Attila Szabo, Ibrahim Akkouh, Jordi Requena Osete, Denis Reis de Assis, Elena Kondratskaya, Timothy Hughes, Thor Ueland, Ole A. Andreassen, Srdjan Djurovic
Pubblicato in: Brain, Behavior, and Immunity, Numero 124, 2025, Pagina/e 144-156, ISSN 0889-1591
Editore: Academic Press
DOI: 10.1016/j.bbi.2024.11.030

SCN1A overexpression, associated with a genomic region marked by a risk variant for a common epilepsy, raises seizure susceptibility

Autori: Katri Silvennoinen, Kinga Gawel, Despina Tsortouktzidis, Julika Pitsch, Saud Alhusaini, Karen M. J. van Loo, Richard Picardo, Zuzanna Michalak, Susanna Pagni, Helena Martins Custodio, James Mills, Christopher D. Whelan, Greig I. de Zubicaray, Katie L. McMahon, Wietske van der Ent, Karolina J. Kirstein-Smardzewska, Ettore Tiraboschi, Jonathan M. Mudge, Adam Frankish, Maria Thom, Margaret J. Wright,
Pubblicato in: Acta Neuropathologica, 2022, ISSN 0001-6322
Editore: Springer Verlag
DOI: 10.1007/s00401-022-02429-0

Linking sarcopenia, brain structure and cognitive performance: a large-scale UK Biobank study

Autori: Tiril P Gurholt, Miguel Germán Borda, Nadine Parker, Vera Fominykh, Rikka Kjelkenes, Jennifer Linge, Dennis van der Meer, Ida E Sønderby, Gustavo Duque, Lars T Westlye, Dag Aarsland, Ole A Andreassen
Pubblicato in: Brain Communications, Numero 6, 2024, ISSN 2632-1297
Editore: Oxford Academic
DOI: 10.1093/braincomms/fcae083

Knockdown of sarcolipin (SLN) impairs substrate utilization in human skeletal muscle cells

Autori: Abel M. Mengeste; Parmeshwar Katare; Andrea Dalmao Fernandez; Jenny Lund; Hege G. Bakke; David Baker; Stefano Bartesaghi; Xiao-Rong Peng; Arild C. Rustan; G. Hege Thoresen; Eili Tranheim Kase
Pubblicato in: Molecular Biology Reports, 2022, ISSN 0301-4851
Editore: Kluwer Academic Publishers
DOI: 10.1007/s11033-022-07387-0

Design and clinical application of injectable hydrogels for musculoskeletal therapy

Autori: Øystein Øvrebø; Giuseppe Perale; Jonathan P. Wojciechowski; Cécile Echalier; Jonathan R. T. Jeffers; Molly M. Stevens; Håvard J. Haugen; Filippo Rossi
Pubblicato in: Bioengineering & Translational Medicine, 2022, ISSN 2380-6761
Editore: American Institute of Chemical Engineers
DOI: 10.1002/btm2.10295

The Lysosomal Calcium Channel TRPML1 Maintains Mitochondrial Fitness in NK Cells through Interorganelle Cross-Talk

Autori: Dennis Clement, Edina K. Szabo, Silje Zandstra Krokeide, Merete Thune Wiiger, Marianna Vincenti, Daniel Palacios, Young-Tae Chang, Christian Grimm, Sandip Patel, Harald Stenmark, Andreas Brech, Rakesh Kumar Majhi, Karl-Johan Malmberg
Pubblicato in: The Journal of Immunology, Numero 211, 2025, Pagina/e 1348-1358, ISSN 0022-1767
Editore: American Association of Immunologists
DOI: 10.4049/jimmunol.2300406

Exploring the gut DNA virome in fecal immunochemical test stool samples reveals associations with lifestyle in a large population-based study

Autori: Paula Istvan, Einar Birkeland, Ekaterina Avershina, Ane S. Kværner, Vahid Bemanian, Barbara Pardini, Sonia Tarallo, Willem M. de Vos, Torbjørn Rognes, Paula Berstad, Trine B. Rounge
Pubblicato in: Nature Communications, Numero 15, 2024, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-024-46033-0

The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics

Autori: Matthew Yoke Wui Ng, Chara Charsou, Ana Lapao, Sakshi Singh, Laura Trachsel-Moncho, Sebastian W. Schultz, Sigve Nakken, Michael J. Munson & Anne Simonsen
Pubblicato in: nature communications, 2022, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-022-3

Projection-based resolved interface 1D-3D mixed-dimension method for embedded tubular network systems

Autori: Timo Koch
Pubblicato in: Computers & Mathematics with Applications, 2022, ISSN 0898-1221
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.camwa.2022.01.021

Mitochondrial Role on Cellular Apoptosis, Autophagy, and Senescence during Osteoarthritis Pathogenesis

Autori: Andrea Dalmao-Fernández, Tamara Hermida-Gómez, Uxia Nogueira-Recalde, Ignacio Rego-Pérez, Francisco J. Blanco-Garcia, Mercedes Fernández-Moreno
Pubblicato in: Cells, Numero 13, 2025, Pagina/e 976, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells13110976

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