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CC-LEGO: robust protein blocks to build cages and layers

Publicaciones

Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice

Autores: ANDREW C. HUNT, JAMES BRETT CASE, YOUNG-JUN PARK, LONGXING CAO, KEJIA WU, ALEXANDRA C. WALLS, ZHUOMING LIU, JOHN E. BOWEN, HSIEN-WEI YEH, SHALLY SAINI, LOUISA HELMS, YAN TING ZHAO, TIEN-YING HSIANG, TYLER N. STARR, INNA GORESHNIK, LISA KOZODOYLAUREN CARTER, RASHMI RAVICHANDRAN, LYDIA B. GREENWADIM L. MATOCHKO, CHRISTY A. THOMSONBASTIAN VÖGELI, ANTJE KRÜGER, LAURA A. VANBLARGAN, RITA E. CHEN, BAO
Publicado en: SCIENCE TRANSLATIONAL MEDICINE, Edición 19466234, 2022, ISSN 1946-6234
Editor: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abn1252

Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks

Autores: Julia Koehler Leman, Sergey Lyskov, Steven M. Lewis, Jared Adolf-Bryfogle, Rebecca F. Alford, Kyle Barlow, Ziv Ben-Aharon, Daniel Farrell, Jason Fell, William A. Hansen, Ameya Harmalkar, Jeliazko Jeliazkov, Georg Kuenze, Justyna D. Krys, Ajasja Ljubetič, Amanda L. Loshbaugh, Jack Maguire, Rocco Moretti, Vikram Khipple Mulligan, Morgan L. Nance, Phuong T. Nguyen, Shane Ó Conchúir, Shourya S. Roy
Publicado en: Nature Communications, Edición 20411723, 2021, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-021-27222-7

Interpreting neural networks for biological sequences by learning stochastic masks

Autores: Johannes Linder, Alyssa La Fleur, Zibo Chen, Ajasja Ljubetič, David Baker, Sreeram Kannan & Georg Seelig
Publicado en: nature machine intelligence, Edición 25225839, 2021, ISSN 2522-5839
Editor: Nature Group Publishing
DOI: 10.1038/s42256-021-00428-6

EMBO Beyond Biology: Connecting peptide, protein, and DNA design with systems chemistry

Autores: DAVE, MASSARANO, KATZIR, STRMŠEK, LJUBETIČ, SEMENTA
Publicado en: Chem, Edición 24519294, 2022, Página(s) 319-324, ISSN 2451-9294
Editor: Elsevier
DOI: 10.1016/j.chempr.2021.12.021

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