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CC-LEGO: robust protein blocks to build cages and layers

Publications

Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice

Author(s): ANDREW C. HUNT, JAMES BRETT CASE, YOUNG-JUN PARK, LONGXING CAO, KEJIA WU, ALEXANDRA C. WALLS, ZHUOMING LIU, JOHN E. BOWEN, HSIEN-WEI YEH, SHALLY SAINI, LOUISA HELMS, YAN TING ZHAO, TIEN-YING HSIANG, TYLER N. STARR, INNA GORESHNIK, LISA KOZODOYLAUREN CARTER, RASHMI RAVICHANDRAN, LYDIA B. GREENWADIM L. MATOCHKO, CHRISTY A. THOMSONBASTIAN VÖGELI, ANTJE KRÜGER, LAURA A. VANBLARGAN, RITA E. CHEN, BAO
Published in: SCIENCE TRANSLATIONAL MEDICINE, Issue 19466234, 2022, ISSN 1946-6234
Publisher: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abn1252

Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks

Author(s): Julia Koehler Leman, Sergey Lyskov, Steven M. Lewis, Jared Adolf-Bryfogle, Rebecca F. Alford, Kyle Barlow, Ziv Ben-Aharon, Daniel Farrell, Jason Fell, William A. Hansen, Ameya Harmalkar, Jeliazko Jeliazkov, Georg Kuenze, Justyna D. Krys, Ajasja Ljubetič, Amanda L. Loshbaugh, Jack Maguire, Rocco Moretti, Vikram Khipple Mulligan, Morgan L. Nance, Phuong T. Nguyen, Shane Ó Conchúir, Shourya S. Roy
Published in: Nature Communications, Issue 20411723, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-27222-7

Interpreting neural networks for biological sequences by learning stochastic masks

Author(s): Johannes Linder, Alyssa La Fleur, Zibo Chen, Ajasja Ljubetič, David Baker, Sreeram Kannan & Georg Seelig
Published in: nature machine intelligence, Issue 25225839, 2021, ISSN 2522-5839
Publisher: Nature Group Publishing
DOI: 10.1038/s42256-021-00428-6

EMBO Beyond Biology: Connecting peptide, protein, and DNA design with systems chemistry

Author(s): DAVE, MASSARANO, KATZIR, STRMŠEK, LJUBETIČ, SEMENTA
Published in: Chem, Issue 24519294, 2022, Page(s) 319-324, ISSN 2451-9294
Publisher: Elsevier
DOI: 10.1016/j.chempr.2021.12.021

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