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Targeted disease prophylaxis in European fish farming

Obiettivo

European aquaculture production provides direct employment to 65.000 people with a turnover of 3 billion €. However, the lack of authorised veterinary medicinal products and the consequent disease outbreaks in farmed fish species costs the sector 20% of the production value. The most appropriate method for disease control, both on economical and ethical grounds, is disease prevention by vaccination. TargetFish will advance the development of existing (but not sufficient) and new prototype vaccines against socio-economically important viral or bacterial pathogens of Atlantic salmon, rainbow trout, common carp, sea bass, sea bream and turbot. The project will develop targeted vaccination strategies for currently sub-optimal and for novel vaccines. Improved vaccines will be brought closer to industrial application by addressing practical issues such as efficacy, safety and delivery route. TargetFish will also establish a knowledge- and technology-base for rational development of next generation fish vaccines. To achieve these challenging tasks, we brought together 29 partners from 11 EU member states, 2 associated countries and 1 International Cooperation Partner Country (ICPC). In this large multidisciplinary consortium an approximate equal number of RTD and SME partners will cooperate closely while keeping an intensive communication with the large vaccine and nutrition industries via an Industry Forum. Specifically, TargetFish will 1) generate knowledge by studying antigens and adjuvants for mucosal routes of administration while analyzing the underpinning protective immune mechanisms; 2) validate this knowledge with response assays for monitoring vaccine efficacy and study safety aspects, including those associated with DNA vaccines; 3) approach implementation of prototype vaccines by optimizing vaccination strategies thus 4) shortening the route to exploitation. Thereby, this project will greatly enhance targeted disease prophylaxis in European fish farming.

Campo scientifico

Not validated

Programma(i)

Argomento(i)

Invito a presentare proposte

FP7-KBBE-2012-6-singlestage
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Meccanismo di finanziamento

CP-TP - Collaborative Project targeted to a special group (such as SMEs)

Coordinatore

WAGENINGEN UNIVERSITY
Contributo UE
€ 857 480,68
Indirizzo
DROEVENDAALSESTEEG 4
6708 PB Wageningen
Paesi Bassi

Mostra sulla mappa
Regione
Oost-Nederland Gelderland Veluwe
Tipo di attività
Higher or Secondary Education Establishments
Contatto amministrativo
Wiegertjes Geert (Dr.)
Collegamenti
Costo totale
Nessun dato

Partecipanti (31)

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Ultimo aggiornamento: 26 Giugno 2017

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Permalink: https://cordis.europa.eu/project/id/311993/it

European Union, 2024