Objective
European aquaculture production provides direct employment to 65.000 people with a turnover of 3 billion €. However, the lack of authorised veterinary medicinal products and the consequent disease outbreaks in farmed fish species costs the sector 20% of the production value. The most appropriate method for disease control, both on economical and ethical grounds, is disease prevention by vaccination. TargetFish will advance the development of existing (but not sufficient) and new prototype vaccines against socio-economically important viral or bacterial pathogens of Atlantic salmon, rainbow trout, common carp, sea bass, sea bream and turbot. The project will develop targeted vaccination strategies for currently sub-optimal and for novel vaccines. Improved vaccines will be brought closer to industrial application by addressing practical issues such as efficacy, safety and delivery route. TargetFish will also establish a knowledge- and technology-base for rational development of next generation fish vaccines. To achieve these challenging tasks, we brought together 29 partners from 11 EU member states, 2 associated countries and 1 International Cooperation Partner Country (ICPC). In this large multidisciplinary consortium an approximate equal number of RTD and SME partners will cooperate closely while keeping an intensive communication with the large vaccine and nutrition industries via an Industry Forum. Specifically, TargetFish will 1) generate knowledge by studying antigens and adjuvants for mucosal routes of administration while analyzing the underpinning protective immune mechanisms; 2) validate this knowledge with response assays for monitoring vaccine efficacy and study safety aspects, including those associated with DNA vaccines; 3) approach implementation of prototype vaccines by optimizing vaccination strategies thus 4) shortening the route to exploitation. Thereby, this project will greatly enhance targeted disease prophylaxis in European fish farming.
Fields of science
Not validated
Not validated
- agricultural sciencesagriculture, forestry, and fisheriesfisheries
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccines
- medical and health scienceshealth sciencesnutrition
- natural sciencesbiological scienceszoologyichthyology
- social scienceseconomics and businessbusiness and managementemployment
Call for proposal
FP7-KBBE-2012-6-singlestage
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Coordinator
6708 PB Wageningen
Netherlands
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Participants (31)
Participation ended
0033 OSLO
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8000 Aarhus C
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AB24 3FX Aberdeen
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AB119DB Aberdeen
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17493 Greifswald-Insel Riems
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28040 MADRID
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08193 Cerdanyola Del Valles
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01100 Viterbo
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75007 Paris
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1433 As
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FK9 4LA Stirling
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35020 Legnaro
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1165 Kobenhavn
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621 00 Brno
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91904 Jerusalem
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30003 Murcia
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CB11 4JU SAFFRON WALDEN
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6009 ALESUND
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8270 HOJBJERG
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51014 TARTU
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RG17 6NE COMPTON NEWBURY
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8700 HORSENS
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41900 SEVILLA
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EH25 9PP MIDLOTHIAN
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44227 Dortmund
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15773 Zografou
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9201291 CERRILLOS SANTIAGO
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8600 SILKEBORG
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7330 Brande
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11591 Jerez de la Frontera
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Participation ended
2800 Kongens Lyngby
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