A high-dimensional approach for unwinding immune-metabolic causes of cardiovascular disease-depression multimorbidities

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Genomics-based identification of a potential causal role for acylcarnitine metabolism in depression

Autores: Yuri Milaneschi; Matthias Arnold; Gabi Kastenmüller; Siamak Mahmoudian Dehkordi; Ranga R. Krishnan; Boadie W. Dunlop; A. John Rush; Brenda W.J.H. Penninx; Rima Kaddurah-Daouk
Publicado en: Journal of Affective Disorders, Edición 18, 2022, ISSN 0165-0327
Editor: Elsevier BV
DOI: 10.1016/j.jad.2022.03.070

The Applications of Single-Cell RNA Sequencing in Atherosclerotic Disease

Autores: Lotte Slenders; Daniëlle E. Tessels; Sander W. van der Laan; Gerard Pasterkamp; Michal Mokry; Michal Mokry
Publicado en: Frontiers in Cardiovascular Medicine, Vol 9 (2022), Edición 21, 2022, ISSN 2297-055X
Editor: Frontiers
DOI: 10.3389/fcvm.2022.826103

Gut microbiome-wide association study of depressive symptoms

Autores: Djawad Radjabzadeh; Jos A. Bosch; André G. Uitterlinden; Aeilko H. Zwinderman; M. Arfan Ikram; Joyce B. J. van Meurs; Annemarie I. Luik; Max Nieuwdorp; Anja Lok; Cornelia M. van Duijn; Robert Kraaij; Najaf Amin
Publicado en: Nature Communications, Edición 18, 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-34502-3

Gene set analysis of transcriptomics data identifies new biological processes associated with early markers of atherosclerosis but not with those of osteoporosis : Atherosclerosis-osteoporosis co/multimorbidity study in the Young Finns Study

Autores: Binisha H. Mishra; Harri Sievänen; Emma Raitoharju; Nina Mononen; Jorma Viikari; Markus Juonala; Marika Laaksonen; Nina Hutri-Kähönen; Mika Kähönen; Olli T. Raitakari; Terho Lehtimäki; Pashupati P. Mishra
Publicado en: Atherosclerosis, Edición 26, 2022, ISSN 0021-9150
Editor: Elsevier BV
DOI: 10.1016/j.atherosclerosis.2022.10.005

Assessment of plasma ceramides as predictor for subclinical atherosclerosis

Autores: Pashupati P. Mishra; Binisha H. Mishra; Leo-Pekka Lyytikäinen; Mika Hilvo; Markus Juonala; Markus Juonala; Mika Kähönen; Nina Hutri-Kähönen; Dimitrios I. Fotiadis; Dimitrios I. Fotiadis; Olli T. Raitakari; Olli T. Raitakari; Reijo Laaksonen; Terho Lehtimäki
Publicado en: Atherosclerosis Plus, Edición 1, 2021, ISSN 2667-0895
Editor: Elsevier BV
DOI: 10.1016/j.athplu.2021.09.005

The gut microbiota and depressive symptoms across ethnic groups

Autores: Jos A. Bosch; Max Nieuwdorp; Aeilko H. Zwinderman; Mélanie Deschasaux; Djawad Radjabzadeh; Robert Kraaij; Mark Davids; Susanne R. de Rooij; Anja Lok
Publicado en: Nature Communications, Edición 19, 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-34504-1

Multi-Omics Integration in a Twin Cohort and Predictive Modeling of Blood Pressure Values

Autores: Gabin Drouard; Miina Ollikainen; Juha Mykkänen; Olli Raitakari; Terho Lehtimäki; Mika Kähönen; Pashupati P. Mishra; Xiaoling Wang; Jaakko Kaprio
Publicado en: OMICS: A journal of integrative biology, Edición 28, 2022, ISSN 1536-2310
Editor: Mary Ann Liebert Inc.
DOI: 10.1089/omi.2021.0201

PolarMorphism enables discovery of shared genetic variants across multiple traits from GWAS summary statistics.

Autores: Joanna von Berg; Michelle ten Dam; Sander W van der Laan; Jeroen de Ridder
Publicado en: Bioinformatics, Edición 23, 2022, ISSN 1367-4803
Editor: Oxford University Press
DOI: 10.1101/2022.01.14.476302

How location and cellular signaling combine to activate the NLRP3 inflammasome

Autores: Anil Akbal; Alesja Dernst; Marta Lovotti; Matthew S. J. Mangan; Róisín M. McManus; Eicke Latz
Publicado en: Cellular and molecular immunology, Edición 19, 2022, ISSN 1672-7681
Editor: Nature Publishing Group
DOI: 10.1038/s41423-022-00922-w

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