Breaking down the wall between human health and environmental testing of endocrine disrupters: EndocRine Guideline Optimisation

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Entry of AOP network into AOP-Wiki and submission for OECD review

Report describing the final AOP network

Guidance document on extrapolation of TD effects across vertebrate classes

Submission of a Guidance Document on extrapolation of TD effects across vertebrate classes

Report on in silico bioavailability triggers applied to TDCs

Status report on the on in silico bioavailability triggers applied to TDCs

Proposal for AOP network-based assay battery for TD testing

Report on AOP network-based prioritization of assays (described as KEs in the respective AOPs) for TD testing

Report on international cooperation

Report on strategic cooperation with international key players from related initiatives and regulatory bodies

Publications

The metabolome of pink-footed goose: Heavy metals and lipid metabolism

Author(s): Mette Jensen; Rikke Poulsen; Rikke Langebæk; Bjørn Munro Jenssen; Johanna Moe; Tomasz M. Ciesielski; Rune Dietz; Christian Sonne; Jesper Madsen; Martin Hansen
Published in: Environmental Research, Issue 231, 116043, 2023, ISSN 0013-9351
Publisher: Academic Press
DOI: 10.1016/j.envres.2023.116043

Highlighting the gaps in hazard and risk assessment of unregulated Endocrine Active Substances in surface waters: retinoids as a European case study

Author(s): Barbara Kubickova, Carmel Ramwell, Klara Hilscherova, Miriam Naomi Jacobs
Published in: Environmental Sciences Europe, Issue 33/1, 2021, Page(s) 20, ISSN 2190-4707
Publisher: Springer Verlag
DOI: 10.1186/s12302-020-00428-0

Thyroid-like hormone signaling in invertebrates and its potential role in initial screening of thyroid hormone system disrupting chemicals

Author(s): Morthorst, J., Holbech, H., de Crozé, N., Matthiessen, P., and LeBlanc, G.
Published in: Integrated Environmental Assessment and Management, 2022, ISSN 1551-3793
Publisher: Society of Environmental Toxicology and Chemistry (SETAC)
DOI: 10.1002/ieam.4632

Functional definition of thyroid hormone response elements based on a synthetic STARR-seq screen.

Author(s): Flamant, F., Zekri, Y. and Guyot, R.
Published in: Endocrinology, Issue 163 (8), 2022, ISSN 0013-7227
Publisher: The Endocrine Society
DOI: 10.1210/endocr/bqac084

AOP Report: Thyroperoxidase Inhibition Leading to Altered Visual Function in Fish via Altered Retinal Layer Structure

Author(s): Gölz, L., Baumann, L., Pannetier, P., Braunbeck, T., Knapen, D., and Vergauwen, L.
Published in: Environmental Toxicology and Chemistry, Issue Vol 41. Issue 8, 2022, ISSN 1552-8618
Publisher: Wiley
DOI: 10.1002/etc.5452

Deiodinase inhibition impairs the formation of the three posterior swim bladder tissue layers during early embryonic development in zebrafish.

Author(s): Van Dingenen, I., Vergauwen, L., Haigis, A., Blackwell, B. R., Stacy, E., Villeneuve, D. L., & Knapen, D.
Published in: Aquatic Toxicology, Issue 261, 106632, 2023, ISSN 0166-445X
Publisher: Elsevier BV
DOI: 10.1016/j.aquatox.2023.106632

Prenatal exposure to paraquat and nanoscaled TiO2 aerosols alters the gene expression of the developing brain

Author(s): Quentin Hamdaoui; Yanis Zekri; Sabine Richard; Denise Aubert; Romain Guyot; Suzy Markossian; Karine Gauthier; François Gaie-Levrel; Anna Bencsik; Frédéric Flamant
Published in: Chemosphere, Issue 287 Part 3, 2022, Page(s) 132253, ISSN 0045-6535
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2021.132253

An Atlas of Thyroid Hormone Receptors’ Target Genes in Mouse Tissues

Author(s): Yanis Zekri; Romain Guyot; Frédéric Flamant
Published in: International Journal of Molecular Sciences, Issue 1, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.1101/2022.08.16.504127

Effect of thyroid hormone‐disrupting chemicals on swim bladder inflation and thyroid hormone‐related gene expression in Japanese medaka and zebrafish.

Author(s): Horie, Y., Nomura, M., Okamoto, K., Takahashi, C., Sato, T., Miyagawa, S., Okamura, H., & Iguchi, T.
Published in: Journal of Applied Toxicology, Issue 42(8), 2022, Page(s) 1385–1395, ISSN 1099-1263
Publisher: Wiley
DOI: 10.1002/jat.4302

Cross-species applicability of an adverse outcome pathway network for thyroid hormone system disruption.

Author(s): Haigis, A., Vergauwen, L., LaLone, C. A., Villeneuve, D. L., O’Brien, J. M., & Knapen, D.
Published in: Toxicological Sciences, 2023, ISSN 1096-6080
Publisher: Oxford University Press
DOI: 10.1093/toxsci/kfad063

Effects of all-trans and 9-cis retinoic acid on differentiating human neural stem cells in vitro

Author(s): Barbara Kubickova, Sarka Martinkova, Dasa Bohaciakova, Marketa Nezvedova, Runze Liu, Ondrej Brozman, Zdeněk Spáčil, Klara Hilscherova
Published in: Toxicology, Issue 487, 2023, Page(s) 153461, ISSN 0300-483X
Publisher: Elsevier BV
DOI: 10.1016/j.tox.2023.153461

Reversibility of thyroid hormone system‐disrupting effects on eye and thyroid follicle development in zebrafish (Danio rerio) embryos.

Author(s): Pannetier, P., Poulsen, R., Gölz, L., Coordes, S., Stegeman, H., Koegst, J., Reger, L., Braunbeck, T., Hansen, M. R. H., & Baumann, L.
Published in: Environmental Toxicology and Chemistry, Issue 42(6), 1276–1292, 2023, ISSN 1552-8618
Publisher: Wiley
DOI: 10.1002/etc.5608

Evidenced-based approaches to support the development of endocrine-mediated Adverse Outcome Pathways: Challenges and Opportunities

Author(s): Audouze, K., Zgheib, E., Abass, K., Baig, A., Forner-Piquer, I., Holbech, H., Knapen, D., Leonards, P., Lupu, D., Palaniswamy, S., Rautio, A., Sapounidou, M. and Martin, O.
Published in: Frontiers in Toxicology, Issue Volume 3, Article 787017, 2021, ISSN 2673-3080
Publisher: Frontiers Media
DOI: 10.3389/ftox.2021.787017

A Pragmatic Approach to Adverse Outcome Pathway Development and Evaluation.

Author(s): Svingen, T., Villeneuve, D. L., Knapen, D., Panagiotou, E. M., Draskau, M. K., Damdimopoulou, P., & O’Brien, J. M.
Published in: Toxicological Sciences, Issue Volume 184 Issue 2, 2021, Page(s) Pages 183–190, ISSN 1096-6080
Publisher: Oxford University Press
DOI: 10.1093/toxsci/kfab113

Relationship between serum thyroid hormones and their associated metabolites, and gene expression bioindicators in the back skin of Rana [Lithobates] catesbeiana tadpoles and frogs during metamorphosis

Author(s): Poulsen, Rikke; Jackman, Shireen H.; Hansen, Martin; Helbing, Caren C.
Published in: Frontiers in Endocrinology, Issue 13: 1103051, 2023, ISSN 1664-2392
Publisher: Frontiers Media
DOI: 10.3389/fendo.2022.1103051

Thyroid hormone as a temporal switch in mouse development

Author(s): Flamant, F. and Ren, J.
Published in: European Thyroid Journal, Issue 12(2), 2023, ISSN 2235-0802
Publisher: Bioscientifica
DOI: 10.1530/etj-22-0225

Developmental exposure to triclosan and benzophenone-2 causes morphological alterations in zebrafish (Danio rerio) thyroid follicles and eyes.

Author(s): Maximilian Kraft; Lisa Gölz; Maximilian Rinderknecht; Johannes Koegst; Thomas Braunbeck; Lisa Baumann
Published in: Environmental Science and Pollution Research, Issue 30, 2023, Page(s) 33711–33724, ISSN 1614-7499
Publisher: Springer Science + Business Media
DOI: 10.1007/s11356-022-24531-2

Effect of in utero and lactational exposure to a thyroid hormone system disrupting chemical on mouse metabolome and brain transcriptome

Author(s): Rikke Poulsen, Yanis Zekri, Romain Guyot, Frédéric Flamant, Martin Hansen
Published in: Environmental Pollution, Issue 340, 2023, Page(s) 122783, ISSN 0269-7491
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envpol.2023.122783

Plastic Nanoparticles Cause Mild Inflammation, Disrupt Metabolic Pathways, Change the Gut Microbiota and Affect Reproduction in Zebrafish: A Full Generation Multi-Omics Study

Author(s): Maranaa, M.H., Poulsen, R., Thormar, E.A., Clausen, C.G., Thitd, A., Mathiessen, H., Jaafar, R., Korbut, R., Magdalene, A., Hansen, B., Hansen, M., Limborg, M.T., Syberg, K., von Gersdorff Jørgensen, L.
Published in: Journal of Hazardous Materials, Issue vol. 424, 2022, Page(s) 127705, ISSN 0304-3894
Publisher: Elsevier BV
DOI: 10.1016/j.jhazmat.2021.127705

A Novel Transgenic Model to Study Thyroid Axis Activity in Early Life Stage Medaka

Author(s): Elise Pesce, Marion Garde, Muriel Rigolet, Andrew J. Tindall, Gregory F. Lemkine, Lisa A. Baumann, Laurent M. Sachs, David Du Pasquier
Published in: Environmental Science & Technology, Issue 58, 2024, Page(s) 99-109, ISSN 0013-936X
Publisher: American Chemical Society
DOI: 10.1021/acs.est.3c05515

A disease-associated mutation in thyroid hormone receptor α1 causes hearing loss and sensory hair cell patterning defects in mice.

Author(s): Affortit, C., Blanc, F., Nasr, J., Ceccato, J.C., Markossian, S., Guyot, R., Puel, J.L., Flamant, F. and Wang, J.
Published in: Science signaling, Issue 15 (738), eabj4583, 2022, ISSN 1945-0877
Publisher: American Association for the Advancement of Science
DOI: 10.1126/scisignal.abj4583

Endocrine disruption in teleosts and amphibians is mediated by anthropogenic and natural environmental factors: implications for risk assessment

Author(s): Werner Kloas, Matthias Stöck, Ilka Lutz, Andrea Ziková-Kloas
Published in: Philosophical Transactions of the Royal Society B: Biological Sciences, Issue 379, 2024, ISSN 0962-8436
Publisher: Royal Society of London
DOI: 10.1098/rstb.2022.0505

Central vs. Peripheral Action of Thyroid Hormone in Adaptive Thermogenesis: A Burning Topic

Author(s): Zekri, Y., Flamant, F., & Gauthier, K.
Published in: Cells, Issue 10(6):1, 2021, Page(s) 1327-1330, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells10061327

In silico bioavailability triggers applied to direct and indirect thyroid hormone disruptors

Author(s): Ralph Kühne, Klára Hilscherová, Marie Smutna, Friederike Leßmöllmann, Gerrit Schüürmann
Published in: Chemosphere, Issue 348, 2024, Page(s) 140611, ISSN 0045-6535
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2023.140611

Mass Spectrometry-Based Zebrafish Toxicometabolomics: A Review of Analytical and Data Quality Challenges.

Author(s): Katyeny Manuela Da Silva; Elias Iturrospe; Chloé Bars; Dries Knapen; Steven Van Cruchten; Adrian Covaci; Alexander L.N. van Nuijs
Published in: Metabolites, Issue 2, 2021, ISSN 2218-1989
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/metabo11090635

Brown adipocytes local response to thyroid hormone is required for adaptive thermogenesis in adult male mice

Author(s): Yanis Zekri; Romain Guyot; Inés Garteizgogeascoa Suñer; Laurence Canaple; Amandine Gautier-Stein; Justine Vily-Petit; Denise Aubert; Sabine Richard; Frédéric Flamant; Karine Gauthier
Published in: Elife 11: e81996, Issue 4, 2022, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.81996

A candidate sex determination locus in amphibians which evolved by structural variation between X- and Y-chromosomes

Author(s): Heiner Kuhl, Wen Hui Tan, Christophe Klopp, Wibke Kleiner, Baturalp Koyun, Mitica Ciorpac, Romain Feron, Martin Knytl, Werner Kloas, Manfred Schartl, Christoph Winkler, Matthias Stöck
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-49025-2

The generation gap in endocrine disruption: Can the integrated fish endocrine disruptor test (iFEDT) bridge the gap by assessing intergenerational effects of thyroid hormone system disruption?

Author(s): Teresa Fagundes, Pauline Pannetier, Lisa Gölz, Laura Behnstedt, Jane Morthorst, Lucia Vergauwen, Dries Knapen, Henrik Holbech, Thomas Braunbeck, Lisa Baumann
Published in: Aquatic Toxicology, Issue 272, 2024, Page(s) 106969, ISSN 0166-445X
Publisher: Elsevier BV
DOI: 10.1016/j.aquatox.2024.106969

Sex chromosomes in meiotic, hemiclonal, clonal and polyploid hybrid vertebrates: along the ‘extended speciation continuum'

Author(s): Stöck, M., Dedukh, D., Reifová, R., Lamatsch, D.K., Starostová, Z. and Janko, K.
Published in: Philosophical Transactions of the Royal Society B: Biological Sciences, Issue vol. 376, no. 1833, 2021, Page(s) p. 20200103, ISSN 0962-8436
Publisher: Royal Society of London
DOI: 10.1098/rstb.2020.0103

PFOS-induced thyroid hormone system disrupted rats display organ-specific changes in their transcriptomes

Author(s): Nichlas Davidsen; Louise Ramhøj; Claus Asger Lykkebo; Indusha Kugathas; Rikke Poulsen; Anna Kjerstine Rosenmai; Bertrand Evrard; Thomas A. Darde; Marta Axelstad; Martin Iain Bahl; Martin Hansen; Frederic Chalmel; Tine Rask Licht; Terje Svingen
Published in: Davidsen , N , Ramhøj , L , Lykkebo , C A , Kugathas , I , Poulsen , R , Rosenmai , A K , Evrard , B , Darde , T A , Axelstad , M , Bahl , M I , Hansen , M , Chalmel , F , Licht , T R & Svingen , T 2022 , ' PFOS-induced thyroid hormone system disrupted rats display organ-specific changes in their transcriptomes ' , Environmental Pollution , vol. 305 , 119340 . https://doi.org/10.1016/j.envpol.202, Issue 2, 2022, Page(s) 119340, ISSN 0269-7491
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envpol.2022.119340

In vitro assessment of thyroid peroxidase inhibition by chemical exposure: comparison of cell models and detection methods

Author(s): Runze Liu, Jiří Novák, Klára Hilscherová
Published in: Archives of Toxicology, Issue 98, 2024, Page(s) 2631-2645, ISSN 0340-5761
Publisher: Springer Verlag
DOI: 10.1007/s00204-024-03766-7

Iodine Bioavailability and Accumulation of Arsenic and Cadmium in Rats Fed Sugar Kelp (Saccharina latissima)

Author(s): Even Fjære; Rikke Poulsen; Arne Duinker; Bjørn Liaset; Martin Hansen; Lise Madsen; Lene Secher Myrmel
Published in: Foods, Issue 11: 24, 2022, ISSN 2304-8158
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/foods11243943

Expanding the Classical Paradigm: What We Have Learnt from Vertebrates about Sex Chromosome Evolution

Author(s): Kratochvíl, L., Stöck, M., Rovatsos, M., Bullejos, M., Herpin, A., Jeffries, D.L., Peichel, C.L., Perrin, N., Valenzuela, N. and Johnson Pokorná, N.
Published in: Philosophical Transactions of the Royal Society B: Biological Sciences, Issue vol. 376, no. 1833, 2021, Page(s) p. 20200097, ISSN 0962-8436
Publisher: Royal Society of London
DOI: 10.1098/rstb.2020.0097

Bisphenol A alters retinal morphology, visually guided behavior, and thyroid hormone levels in zebrafish larvae

Author(s): Sina N. Volz, Rikke Poulsen, Martin Hansen, Henrik Holbech
Published in: Chemosphere, Issue 348, 2024, Page(s) 140776, ISSN 0045-6535
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2023.140776

Polyquaternium polymers cause inflammatory response and alterations of the lipidome in Danio rerio larvae

Author(s): Anna Magdalene Brun Hansen, Rikke Poulsen, Louise von Gersdorff Jørgensen, Martin Hansen
Published in: Journal of Hazardous Materials Letters, Issue 5, 2024, Page(s) 100095, ISSN 2666-9110
Publisher: Elsevier
DOI: 10.1016/j.hazl.2023.100095

Tetrabromobisphenol A effects on differentiating mouse embryonic stem cells reveals unexpected impact on immune system.

Author(s): Tribondeau, A., Sachs, L.M. and Buisine, N.
Published in: Frontiers in Genetics 13:996826, 2022, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2022.996826

Overlapping action of T3 and T4 during Xenopus laevis development

Author(s): Alicia Tribondeau, David Du Pasquier, Médine Benchouaia, Corinne Blugeon, Nicolas Buisine, Laurent M. Sachs
Published in: Frontiers in Endocrinology, Issue 15, 2024, Page(s) 1360188, ISSN 1664-2392
Publisher: Frontiers
DOI: 10.3389/fendo.2024.1360188

Iopanoic acid alters thyroid hormone-related gene expression, thyroid hormone levels, swim bladder inflation, and swimming performance in Japanese medaka

Author(s): Yoshifumi Horie, Ayaka Sawada, Uaciquete Dorcas, Babu Rajendran Ramaswamy, Taisen Iguchi
Published in: Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, Issue 281, 2024, Page(s) 109930, ISSN 1532-0456
Publisher: Elsevier BV
DOI: 10.1016/j.cbpc.2024.109930

Interdependence of Thyroid and Corticosteroid Signaling in Vertebrate Developmental Transitions

Author(s): Karine Rousseau, Sylvie Dufour, Laurent M. Sachs
Published in: Frontiers in Ecology and Evolution, Issue 9, 2021, ISSN 2296-701X
Publisher: Frontiers
DOI: 10.3389/fevo.2021.735487

A Pivotal Genetic Program Controlled by Thyroid Hormone during the Maturation of GABAergic Neurons

Author(s): Sabine Richard, Romain Guyot, Martin Rey-Millet, Margaux Prieux, Suzy Markossian, Denise Aubert, Frédéric Flamant
Published in: iScience, Issue 23/3, 2020, Page(s) 100899, ISSN 2589-0042
Publisher: Cell Press
DOI: 10.1016/j.isci.2020.100899

ERGO: Breaking Down the Wall between Human Health and Environmental Testing of Endocrine Disrupters

Author(s): Henrik Holbech, Peter Matthiessen, Martin Hansen, Gerrit Schüürmann, Dries Knapen, Marieke Reuver, Frédéric Flamant, Laurent Sachs, Werner Kloas, Klara Hilscherova, Marc Leonard, Jürgen Arning, Volker Strauss, Taisen Iguchi, Lisa Baumann
Published in: International Journal of Molecular Sciences, Issue 21/8, 2020, Page(s) 2954, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21082954

Effect of Thyroperoxidase and Deiodinase Inhibition on Anterior Swim Bladder Inflation in the Zebrafish

Author(s): Evelyn Stinckens, Lucia Vergauwen, Brett R. Blackwell, Gerald T. Ankley, Daniel L. Villeneuve, Dries Knapen
Published in: Environmental Science & Technology, Issue 54/10, 2020, Page(s) 6213-6223, ISSN 0013-936X
Publisher: American Chemical Society
DOI: 10.1021/acs.est.9b07204

Toward an AOP Network-Based Tiered Testing Strategy for the Assessment of Thyroid Hormone Disruption

Author(s): Dries Knapen, Evelyn Stinckens, Jenna E. Cavallin, Gerald T. Ankley, Henrik Holbech, Daniel L. Villeneuve, Lucia Vergauwen
Published in: Environmental Science & Technology, 2020, ISSN 0013-936X
Publisher: American Chemical Society
DOI: 10.1021/acs.est.9b07205

The thyroid hormone system disrupting potential of resorcinol in fish

Author(s): Dingenen, I.V., Andersen, E., Volz, S., Christiansen, M., Novák, J., Haigis, A.C., Stacy, E., Blackwell, B.R., Villeneuve, D.L., Vergauwen, L., Hilscherová, K., Holbech, H. and Knapen, D.
Published in: Ecotoxicology and Environmental Safety, Issue 284, 2024, Page(s) 116995, ISSN 1090-2414
Publisher: Elsevier
DOI: 10.1016/j.ecoenv.2024.116995

Combining transcriptomics and metabolomics to assess neurodevelopmental alteration caused by in utero exposure of mice to three putative thyroid hormone system disruptors

Author(s): Yanis Zekri, Rikke Poulsen, Martin Hansen, Frédéric Flamant, Romain Guyot
Published in: Toxicology, 2024, Page(s) 153905, ISSN 0300-483X
Publisher: Elsevier BV
DOI: 10.1016/j.tox.2024.153905

Development of a Zebrafish Embryo‐Based Test System for Thyroid Hormone System Disruption: 3Rs in Ecotoxicological Research

Author(s): Lisa Gölz, Melanie Blanc‐Legendre, Maximilian Rinderknecht, Laura Behnstedt, Sara Coordes, Luisa Reger, Sacha Sire, Xavier Cousin, Thomas Braunbeck, Lisa Baumann
Published in: Environmental Toxicology and Chemistry, 2024, ISSN 0730-7268
Publisher: Society of Environmental Toxicology and Chemistry
DOI: 10.1002/etc.5878

In vitro assessment of pesticides capacity to act as agonists/antagonists of the thyroid hormone nuclear receptors

Author(s): Yanis Zekri, Laure Dall Agnol, Frédéric Flamant, Romain Guyot
Published in: iScience, Issue 24/9, 2021, Page(s) 102957, ISSN 2589-0042
Publisher: Elsevier
DOI: 10.1016/j.isci.2021.102957

Is periventricular heterotopia a useful endpoint for developmental thyroid hormone system disruption in mouse toxicity studies?

Author(s): Ramhøj, L., Guyot, R., Svingen, T., Kortenkamp, A., Flamant, F. and Axelstad, M.
Published in: Regulatory Toxicology and Pharmacology, Issue 142, 105445, 2023, ISSN 0273-2300
Publisher: Academic Press
DOI: 10.1016/j.yrtph.2023.105445

Adverse effects of thyroid-hormone-disrupting chemicals 6-propyl-2-thiouracil and tetrabromobisphenol A on Japanese medaka (Oryzias latipes).

Author(s): Horie, Y., Yamagishi, T., Yamamoto, J., Suzuki, M., Onishi, Y., Chiba, T., Miyagawa, S., Lange, A., Tyler, C. R., Okamura, H., & Iguchi, T.
Published in: Comparative Biochemistry and Physiology C-toxicology & Pharmacology, Issue 263, 109502, 2023, ISSN 1532-0456
Publisher: Elsevier BV
DOI: 10.1016/j.cbpc.2022.109502

Thyroid and Corticosteroid Signaling in Amphibian Metamorphosis

Author(s): Bidisha, P., Sterner, Z.R., Buchholz, D.R., Shi, Y.B. and Sachs, L.M.
Published in: Cells 11, no. 10, 2022, Page(s) 1595, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells11101595

Detailed review paper (DRP) on the thyroid hormone system in fish and identification of potential thyroid hormone system related endpoints for inclusion in existing OECD fish Test Guidelines

Author(s): OECD
Published in: OECD Series on Testing and Assessment, Issue No. 381, 2023
Publisher: OECD Publishing

Deiodinase 1 inhibition leading to increased mortality via reduced posterior swim bladder inflation

Author(s): Vergauwen, L., Stinckens, E., Villeneuve, D.L., Knapen, D.
Published in: OECD Series on Adverse Outcome Pathways, Issue No. 24, 2022
Publisher: OECD Publishing
DOI: 10.1787/9cb525e9-en.

Deiodinase 1 inhibition leading to increased mortality via reduced anterior swim bladder inflation”,

Author(s): Vergauwen, L., Stinckens, E., Villeneuve, D.L., Knapen, D.
Published in: OECD Series on Adverse Outcome Pathways, Issue No. 25, 2022
Publisher: OECD Publishing
DOI: 10.1787/9f651c16-en

Deiodinase 2 inhibition leading to increased mortality via reduced posterior swim bladder inflation

Author(s): Vergauwen, L., Stinckens, E., Villeneuve, D.L., Knapen, D.
Published in: OECD Series on Adverse Outcome Pathways, Issue No. 22, 2022
Publisher: OECD Publishing
DOI: 10.1787/dc406014-en.

Deiodinase 2 inhibition leading to increased mortality via reduced anterior swim bladder inflation

Author(s): Vergauwen, L., Stinckens, E., Villeneuve, D.L., Knapen, D.
Published in: OECD Series on Adverse Outcome Pathways, Issue No. 23, 2022
Publisher: OECD Publishing
DOI: 10.1787/b1bf0bea-en.

Thyroperoxidase inhibition leading to increased mortality via reduced anterior swim bladder inflation

Author(s): Vergauwen, L., Stinckens, E., Villeneuve, D.L., Knapen, D.
Published in: OECD Series on Adverse Outcome Pathways, Issue No.26, 2022
Publisher: OECD Publishing
DOI: 10.1787/447c5cba-en

Mechanistic evaluation of rodent studies for selected thyroid disrupting chemicals (TDCs). From key events to adverse outcome pathway.

Author(s): Anna Melina Steinbach
Published in: 2021
Publisher: University of Milan and BASF SE

"Sex chromosomes in so-called ""asexual"" hybrid vertebrates: along the ‘extended speciation continuum’"

Author(s): Matthias Stöck , Dmitrij Dedukh , Radka Reifová , Dunja K. Lamatsch , Zuzana Starostová, Karel Janko
Published in: """ESEB Satellite Symposium Genomic signatures and consequences of sex and asexuality 16.06.2021 – 17.06.2021, all times indicated are CEST Hosts Astrid Böhne, ZFMK and Philipp Schiffer, University of Cologne """, 2021
Publisher: European Society of Evolutionary Biology

Searching for OpenAIRE data...

Deliverables

Publications

Share this page

Download