Skip to main content
European Commission logo
Deutsch Deutsch
CORDIS - Forschungsergebnisse der EU
CORDIS
CORDIS Web 30th anniversary CORDIS Web 30th anniversary

A new crop protection strategy by chemical priming of the plant immune system

Projektbeschreibung

Wachsender Pflanzenschutz zur Bekämpfung globaler Ertragsverluste

Jedes Jahr geht weltweit ein großer Teil der Ernteerträge durch Pflanzenkrankheiten verloren, was zu erheblichen wirtschaftlichen Verlusten für die Landwirtschaft Betreibenden und zu Nahrungsmittelknappheit für die Weltbevölkerung führt. Pestizide waren bisher das Mittel der Wahl, um diese Verluste zu verringern, aber ihre negativen Auswirkungen auf die Gesundheit und die Umwelt sowie die zunehmende Resistenz gegen Pestizide haben Bedenken aufkommen lassen. Das vom Europäischen Forschungsrat finanzierte Projekt ChemPrime zielt darauf ab, eine Pflanzenschutztechnologie zu entwickeln, die auf der Aktivierung des pflanzlichen Immunsystems beruht und die Abwehrkräfte der Pflanze gegen Angreifer stärkt. Im Rahmen des Projekts wird die Wirksamkeit von R-beta-Homoserin gegen eine Reihe von Pflanzenkrankheiten untersucht und eine kommerziell tragfähige Pflanzenschutzstrategie durch Co-Design mit kommerziellen Interessengruppen entwickelt.

Ziel

A large proportion of global crop yield is annually lost to plant diseases. While pesticides help to reduce these losses, there are growing concerns about pesticide resistance and their impacts on health and environment. The objective of this proof-of-concept project is to develop a crop protection technology that is based on priming of the plant’s own immune system, providing an enhanced defensive capacity to resist attackers. While priming is considered attractive for exploitation in integrated pest and disease management, chemical priming agents have never reached their full economic potential due to undesirable non-target effects on plant growth and yield. My former ERC project (‘Prime-A-Plant ́) has revealed key insights in the mechanisms by which plants perceive and respond to priming-inducing chemicals. We showed that the benefits of priming by beta-aminobutyric acid (BABA) can be uncoupled from the associated stress response (Luna et al. 2014; Nature Chem. Biol.). More recently, we discovered a structural analogue of BABA, R-beta-homoserine (RBH), which primes plant defences against multiple diseases without affecting growth (Buswell et al. 2018; New Phytol.). The current ‘ChemPrime’ project aims to develop these discoveries into a crop protection strategy through co-design with commercial stakeholders. The first project part involves translational research to make the concept more attractive for adoption by commercial stakeholders. We will examine the effectiveness of RBH against a range of economically relevant crop diseases, identify genetic targets in crops to improve the effectiveness of the RBH priming response, assess chemical residues in crop products and waste streams, and optimise RBH formulation for applications in different production systems. The second project part involves engagement activities to initiate collaborative research & development with agri-tech companies and develop the concept into a commercially viable crop protection strategy.

Gastgebende Einrichtung

THE UNIVERSITY OF SHEFFIELD
Netto-EU-Beitrag
€ 148 318,00
Adresse
FIRTH COURT WESTERN BANK
S10 2TN Sheffield
Vereinigtes Königreich

Auf der Karte ansehen

Region
Yorkshire and the Humber South Yorkshire Sheffield
Aktivitätstyp
Higher or Secondary Education Establishments
Links
Gesamtkosten
€ 148 318,00

Begünstigte (1)