Targeting Meniscus Degradation in Osteoarthritis

Pubblicazioni

Relating MR relaxation times of ex vivo meniscus to tissue degeneration through comparison with histopathology

Autori: Emma Einarsson, Jonas Svensson, Elin Folkesson, Iida Kestilä, Jon Tjörnstrand, Pernilla Peterson, Mikko A.J. Finnilä, H. Velocity Hughes, Aleksandra Turkiewicz, Simo Saarakkala, Martin Englund
Pubblicato in: Osteoarthritis and Cartilage Open, Numero 2/2, 2020, Pagina/e 100061, ISSN 2665-9131
Editore: Elsevier
DOI: 10.1016/j.ocarto.2020.100061

Quantitative three-dimensional collagen orientation analysis of human meniscus posterior horn in health and osteoarthritis using micro-computed tomography

Autori: V.-P. Karjalainen, I. Kestilä, M.A. Finnilä, E. Folkesson, A. Turkiewicz, P. Önnerfjord, V. Hughes, J. Tjörnstrand, M. Englund, S. Saarakkala
Pubblicato in: Osteoarthritis and Cartilage, 2021, ISSN 1063-4584
Editore: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2021.01.009

Exploring the Early Molecular Pathogenesis of Osteoarthritis Using Differential Network Analysis of Human Synovial Fluid

Autori: Martin Rydén, Amanda Sjögren, Patrik Önnerfjord, Aleksandra Turkiewicz, Jon Tjörnstrand, Martin Englund, Neserin Ali
Pubblicato in: Molecular & Cellular Proteomics, Numero 23, 2024, Pagina/e 100785, ISSN 1535-9476
Editore: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.mcpro.2024.100785

Imaging-based assessment of fatty acid composition in human bone marrow adipose tissue at 7 T: Method comparison and in vivo feasibility

Autori: Sevgi Emin, Edwin H. G. Oei, Martin Englund, Pernilla Peterson
Pubblicato in: Magnetic Resonance in Medicine, 2023, ISSN 1522-2594
Editore: Wiley Periodicals LLC
DOI: 10.1002/mrm.29623

3D analysis and grading of calcifications from ex VIVO human meniscus

Autori: I. Hellberg, V.P. Karjalainen, M.A.J. Finnilä, E. Jonsson, A. Turkiewicz , P. Önnerfjord, V. Hughes, J. Tjörnstrand, M. Englund, S. Saarakkala
Pubblicato in: Osteoarthritis and Cartilage, Numero 31:4, 2022, Pagina/e 482-492, ISSN 1063-4584
Editore: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2022.10.016

Identification and quantification of degradome components in human synovial fluid reveals an increased proteolytic activity in knee osteoarthritis patients vs controls

Autori: Martin Rydén, Aleksandra Turkiewicz, Patrik Önnerfjord, Jon Tjörnstrand, Martin Englund, Neserin Ali
Pubblicato in: PROTEOMICS, Numero 23, 2023, ISSN 1615-9853
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/pmic.202300040

A human meniscus explant model for studying early events in osteoarthritis development by proteomics

Autori: Martin Rydén, Karin Lindblom, Aida Yifter‐Lindgren, Aleksandra Turkiewicz, Anders Aspberg, Viveka Tillgren, Martin Englund, Patrik Önnerfjord
Pubblicato in: Journal of Orthopaedic Research, Numero 41, 2023, Pagina/e 2765-2778, ISSN 0736-0266
Editore: Elsevier BV
DOI: 10.1002/jor.25633

Proteomic profiling of human menisci from mild joint degeneration and end-stage osteoarthritis versus healthy controls

Autori: Rocío Paz-González, Aleksandra Turkiewicz, Neserin Ali, Cristina Ruiz-Romero, Francisco J. Blanco, Martin Englund, Patrik Önnerfjord
Pubblicato in: Osteoarthritis and Cartilage Open, Numero 5, 2023, Pagina/e 100417, ISSN 2665-9131
Editore: Elsevier
DOI: 10.1016/j.ocarto.2023.100417

Ultra-high field magnetic resonance imaging parameter mapping in the posterior horn of ex vivo human menisci

Autori: E. Olsson, E. Folkesson, P. Peterson, P. Önnerfjord, J. Tjörnstrand, H.V. Hughes, M. Englund, J. Svensson
Pubblicato in: Osteoarthritis and Cartilage, Numero 27/3, 2019, Pagina/e 476-483, ISSN 1063-4584
Editore: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2018.12.003

Proteomics profiling of human synovial fluid suggests increased protein interplay in early-osteoarthritis (OA) that is lost in late-stage OA

Autori: Neserin Ali, Aleksandra Turkiewicz, Velocity Hughes, Elin Folkesson, Jon Tjörnstand, Paul Neuman, Patrik Önnerfjord, Martin Englund
Pubblicato in: Molecular & cellular proteomics: MCP, Numero 21:3, 2022, Pagina/e 100200, ISSN 1535-9484
Editore: ASBMB PUBLICATIONS
DOI: 10.1016/j.mcpro.2022.100200

Three-dimensional microstructure of human meniscus posterior horn in health and osteoarthritis

Autori: I. Kestilä, E. Folkesson, M.A. Finnilä, A. Turkiewicz, P. Önnerfjord, V. Hughes, J. Tjörnstrand, M. Englund, S. Saarakkala
Pubblicato in: Osteoarthritis and Cartilage, Numero 27/12, 2019, Pagina/e 1790-1799, ISSN 1063-4584
Editore: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2019.07.003

Proteomic characterization of the normal human medial meniscus body using data‐independent acquisition mass spectrometry

Autori: Elin Folkesson, Aleksandra Turkiewicz, Martin Rydén, Harini Velocity Hughes, Neserin Ali, Jon Tjörnstrand, Patrik Önnerfjord, Martin Englund
Pubblicato in: Journal of Orthopaedic Research, 2020, ISSN 0736-0266
Editore: Elsevier BV
DOI: 10.1002/jor.24602

Proteomic comparison of osteoarthritic and reference human menisci using data-independent acquisition mass spectrometry

Autori: E. Folkesson, A. Turkiewicz, N. Ali, M. Rydén, H.V. Hughes, J. Tjörnstrand, P. Önnerfjord, M. Englund
Pubblicato in: Osteoarthritis and Cartilage, Numero 28/8, 2020, Pagina/e 1092-1101, ISSN 1063-4584
Editore: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2020.05.001

Altered co-expression patterns of synovial fluid proteins related to the immune system and extracellular matrix organization in late stage OA, compared to non-OA controls

Autori: Jenny Lönsjö, Martin Rydén, Aleksandra Turkiewicz, Velocity Hughes, Jon Tjörnstand, Patrik Önnerfjord, Martin Englund, Neserin Ali
Pubblicato in: bioRxiv, 2023
Editore: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.03.20.533133

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