Targeting Meniscus Degradation in Osteoarthritis

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Relating MR relaxation times of ex vivo meniscus to tissue degeneration through comparison with histopathology

Author(s): Emma Einarsson, Jonas Svensson, Elin Folkesson, Iida Kestilä, Jon Tjörnstrand, Pernilla Peterson, Mikko A.J. Finnilä, H. Velocity Hughes, Aleksandra Turkiewicz, Simo Saarakkala, Martin Englund
Published in: Osteoarthritis and Cartilage Open, Issue 2/2, 2020, Page(s) 100061, ISSN 2665-9131
Publisher: Elsevier
DOI: 10.1016/j.ocarto.2020.100061

Quantitative three-dimensional collagen orientation analysis of human meniscus posterior horn in health and osteoarthritis using micro-computed tomography

Author(s): V.-P. Karjalainen, I. Kestilä, M.A. Finnilä, E. Folkesson, A. Turkiewicz, P. Önnerfjord, V. Hughes, J. Tjörnstrand, M. Englund, S. Saarakkala
Published in: Osteoarthritis and Cartilage, 2021, ISSN 1063-4584
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2021.01.009

Exploring the Early Molecular Pathogenesis of Osteoarthritis Using Differential Network Analysis of Human Synovial Fluid

Author(s): Martin Rydén, Amanda Sjögren, Patrik Önnerfjord, Aleksandra Turkiewicz, Jon Tjörnstrand, Martin Englund, Neserin Ali
Published in: Molecular & Cellular Proteomics, Issue 23, 2024, Page(s) 100785, ISSN 1535-9476
Publisher: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.mcpro.2024.100785

Imaging-based assessment of fatty acid composition in human bone marrow adipose tissue at 7 T: Method comparison and in vivo feasibility

Author(s): Sevgi Emin, Edwin H. G. Oei, Martin Englund, Pernilla Peterson
Published in: Magnetic Resonance in Medicine, 2023, ISSN 1522-2594
Publisher: Wiley Periodicals LLC
DOI: 10.1002/mrm.29623

3D analysis and grading of calcifications from ex VIVO human meniscus

Author(s): I. Hellberg, V.P. Karjalainen, M.A.J. Finnilä, E. Jonsson, A. Turkiewicz , P. Önnerfjord, V. Hughes, J. Tjörnstrand, M. Englund, S. Saarakkala
Published in: Osteoarthritis and Cartilage, Issue 31:4, 2022, Page(s) 482-492, ISSN 1063-4584
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2022.10.016

Identification and quantification of degradome components in human synovial fluid reveals an increased proteolytic activity in knee osteoarthritis patients vs controls

Author(s): Martin Rydén, Aleksandra Turkiewicz, Patrik Önnerfjord, Jon Tjörnstrand, Martin Englund, Neserin Ali
Published in: PROTEOMICS, Issue 23, 2023, ISSN 1615-9853
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/pmic.202300040

A human meniscus explant model for studying early events in osteoarthritis development by proteomics

Author(s): Martin Rydén, Karin Lindblom, Aida Yifter‐Lindgren, Aleksandra Turkiewicz, Anders Aspberg, Viveka Tillgren, Martin Englund, Patrik Önnerfjord
Published in: Journal of Orthopaedic Research, Issue 41, 2023, Page(s) 2765-2778, ISSN 0736-0266
Publisher: Elsevier BV
DOI: 10.1002/jor.25633

Proteomic profiling of human menisci from mild joint degeneration and end-stage osteoarthritis versus healthy controls

Author(s): Rocío Paz-González, Aleksandra Turkiewicz, Neserin Ali, Cristina Ruiz-Romero, Francisco J. Blanco, Martin Englund, Patrik Önnerfjord
Published in: Osteoarthritis and Cartilage Open, Issue 5, 2023, Page(s) 100417, ISSN 2665-9131
Publisher: Elsevier
DOI: 10.1016/j.ocarto.2023.100417

Ultra-high field magnetic resonance imaging parameter mapping in the posterior horn of ex vivo human menisci

Author(s): E. Olsson, E. Folkesson, P. Peterson, P. Önnerfjord, J. Tjörnstrand, H.V. Hughes, M. Englund, J. Svensson
Published in: Osteoarthritis and Cartilage, Issue 27/3, 2019, Page(s) 476-483, ISSN 1063-4584
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2018.12.003

Proteomics profiling of human synovial fluid suggests increased protein interplay in early-osteoarthritis (OA) that is lost in late-stage OA

Author(s): Neserin Ali, Aleksandra Turkiewicz, Velocity Hughes, Elin Folkesson, Jon Tjörnstand, Paul Neuman, Patrik Önnerfjord, Martin Englund
Published in: Molecular & cellular proteomics: MCP, Issue 21:3, 2022, Page(s) 100200, ISSN 1535-9484
Publisher: ASBMB PUBLICATIONS
DOI: 10.1016/j.mcpro.2022.100200

Three-dimensional microstructure of human meniscus posterior horn in health and osteoarthritis

Author(s): I. Kestilä, E. Folkesson, M.A. Finnilä, A. Turkiewicz, P. Önnerfjord, V. Hughes, J. Tjörnstrand, M. Englund, S. Saarakkala
Published in: Osteoarthritis and Cartilage, Issue 27/12, 2019, Page(s) 1790-1799, ISSN 1063-4584
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2019.07.003

Proteomic characterization of the normal human medial meniscus body using data‐independent acquisition mass spectrometry

Author(s): Elin Folkesson, Aleksandra Turkiewicz, Martin Rydén, Harini Velocity Hughes, Neserin Ali, Jon Tjörnstrand, Patrik Önnerfjord, Martin Englund
Published in: Journal of Orthopaedic Research, 2020, ISSN 0736-0266
Publisher: Elsevier BV
DOI: 10.1002/jor.24602

Proteomic comparison of osteoarthritic and reference human menisci using data-independent acquisition mass spectrometry

Author(s): E. Folkesson, A. Turkiewicz, N. Ali, M. Rydén, H.V. Hughes, J. Tjörnstrand, P. Önnerfjord, M. Englund
Published in: Osteoarthritis and Cartilage, Issue 28/8, 2020, Page(s) 1092-1101, ISSN 1063-4584
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2020.05.001

Altered co-expression patterns of synovial fluid proteins related to the immune system and extracellular matrix organization in late stage OA, compared to non-OA controls

Author(s): Jenny Lönsjö, Martin Rydén, Aleksandra Turkiewicz, Velocity Hughes, Jon Tjörnstand, Patrik Önnerfjord, Martin Englund, Neserin Ali
Published in: bioRxiv, 2023
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.03.20.533133

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