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CORDIS Web 30th anniversary CORDIS Web 30th anniversary

Establishing the Hungarian Center of Excellence for Molecular Medicine in partnership with EMBL

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Detection and Functional Evaluation of the P2X7 Receptor in hiPSC Derived Neurons and Microglia-Like Cells. Front Mol Neurosci

Autori: Francistiová L, Vörös K, Lovász Z, Dinnyés A, Kobolák J.
Pubblicato in: Frontiers in molecular neuroscience, 2022, ISSN 1662-5099
Editore: Frontiers Research Foundation
DOI: 10.3389/fnmol.2021.793769

Regulation of Orai channels by intracellular pH: one step closer to understand CRAC channel biology? J Physiol.

Autori: Maléth J.
Pubblicato in: Journal of Physiology, 2022, ISSN 1469-7793
Editore: Wiley-Blackwell Publishing Ltd
DOI: 10.1113/jp282680

Sierra RO, Pedraza LK, Barcsai L, Pejin A, Li Q, Kozák G, Takeuchi Y, Nagy AJ, Lőrincz ML, Devinsky O, Buzsáki G, Berényi A.

Autori: Closed-loop brain stimulation augments fear extinction in male rats. Nat Commun.
Pubblicato in: Nature Communications, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-023-39546-7

Phenotypic plasticity of melanocytes derived from human adult skin

Autori: Dániel László Vidács, Zoltán Veréb, Renáta Bozó, Lili Borbála Flink, Hilda Polyánka, István Balázs Németh, Szilárd Póliska, Benjamin Tamás Papp, Máté Manczinger, Róbert Gáspár, Seyedmohsen Mirdamadi, Lajos Kemény, Zsuzsanna Bata‐Csörgő
Pubblicato in: Pigment Cell & Melanoma Research, 2021, ISSN 1755-1471
Editore: Basil Blackwell
DOI: 10.1111/pcmr.13012

Next-Generation Sequencing-Based Genomic Profiling of Children with Acute Myeloid Leukemia.

Autori: Krizsán S, Péterffy B, Egyed B, Nagy T, Sebestyén E, Hegyi LL, Jakab Z, Erdélyi DJ, Müller J, Péter G, Csanádi K, Kállay K, Kriván G, Barna G, Bedics G, Haltrich I, Ottóffy G, Csernus K, Vojcek Á, Tiszlavicz LG, Gábor KM, Kelemen Á, Hauser P, Gaál Z, Szegedi I, Ujfalusi A, Kajtár B, Kiss C, Matolcsy A, Tímár B, Kovács G, Alpár D, Bödör C.
Pubblicato in: Journal of Molecular Diagnostics, 2023, ISSN 1525-1578
Editore: American Society for Investigative Pathology
DOI: 10.1016/j.jmoldx.2023.04.004

Herpes Simplex Virus Infection Alters the Immunological Properties of Adipose-Tissue-Derived Mesenchymal-Stem Cells.

Autori: Kun-Varga A, Gubán B, Miklós V, Parvaneh S, Guba M, Szűcs D, Monostori T, Varga J, Varga Á, Rázga Z, Bata-Csörgő Z, Kemény L, Megyeri K, Veréb Z.
Pubblicato in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms241511989

Candida albicans Enhances the Progression of Oral Squamous Cell Carcinoma In Vitro and In Vivo.

Autori: Vadovics M, Ho J, Igaz N, Alföldi R, Rakk D, Veres É, Szücs B, Horváth M, Tóth R, Szücs A, Csibi A, Horváth P, Tiszlavicz L, Vágvölgyi C, Nosanchuk JD, Szekeres A, Kiricsi M, Henley-Smith R, Moyes DL, Thavaraj S, Brown R, Puskás LG, Naglik JR, Gácser A.
Pubblicato in: mBio, 2022, ISSN 2150-7511
Editore: American Society for Microbiology
DOI: 10.1128/mbio.03144-21

Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.

Autori: Mansouri L, Thorvaldsdottir B, Sutton LA, Karakatsoulis G, Meggendorfer M, Parker H, Nadeu F, Brieghel C, Laidou S, Moia R, Rossi D, Catherwood M, Kotaskova J, Delgado J, Rodríguez-Vicente AE, Benito R, Rigolin GM, Bonfiglio S, Scarfo L, Mattsson M, Davis Z, Gogia A, Rani L, Baliakas P, Foroughi-Asl H, Jylhä C, Skaftason A, Rapado I, Miras F, Martinez-Lopez J, de la Serna J, Rivas JMH, Thornton
Pubblicato in: Leukemia, 2022, ISSN 0887-6924
Editore: Nature Publishing Group
DOI: 10.1038/s41375-022-01802-y

Characterization and functional analysis of zinc trafficking in the human fungal pathogen Candida parapsilosis.

Autori: Takács T, Németh MT, Bohner F, Vágvölgyi C, Jankovics F, Wilson D, Gácser A.
Pubblicato in: Open biology, 2022, ISSN 2046-2441
Editore: Royal Society Publishing
DOI: 10.1098/rsob.220077

Molecular pathology of the R117H cystic fibrosis mutation is explained by loss of a hydrogen bond.

Autori: Simon MA, Csanády L.
Pubblicato in: eLife Sciences Publications, 2019, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.74693

Influence of cardiometabolic comorbidities on myocardial function, infarction, and CARDIOPROTECTION: Role of cardiac redox signaling

Autori: Ioanna Andreadou, Andreas Daiber, Gary F. Baxter, Maria.Felice Brizzi, Fabio di Lisa, Nina Kaludercic, Antigone Lazou, Zoltán.V. Varga, Coert Zuurbier, Rainer Schulz, Péter Ferdinandy
Pubblicato in: Free Radical Biology and Medicine, 2021, ISSN 0891-5849
Editore: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2021.02.012

Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes.

Autori: Rönn T, Ofori JK, Perfilyev A, Hamilton A, Pircs K, Eichelmann F, Garcia-Calzon S, Karagiannopoulos A, Stenlund H, Wendt A, Volkov P, Schulze MB, Mulder H, Eliasson L, Ruhrmann S, Bacos K, Ling C.
Pubblicato in: Nature Communications, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-023-43719-9

Antineoplastic drugs inducing cardiac and vascular toxicity - An update.

Autori: Barachini S, Ghelardoni S, Varga ZV, Mehanna RA, Montt-Guevara MM, Ferdinandy P, Madonna R.
Pubblicato in: Vascular Pharmacology, 2023, ISSN 1879-3649
Editore: Elsevier
DOI: 10.1016/j.vph.2023.107223

The genomic landscape of teenage and young adult T‐cell acute lymphoblastic leukemia

Autori: Marcela B. Mansur, Caroline L. Furness, Sirintra Nakjang, Amir Enshaei, Donat Alpar, Sue M. Colman, Lynne Minto, Julie Irving, Beth V. Poole, Elda P. Noronha, Suvi Savola, Sameena Iqbal, John Gribben, Maria S. Pombo‐de‐Oliveira, Tony M. Ford, Mel F. Greaves, Frederik W. Delft
Pubblicato in: Cancer Medicine, 2021, ISSN 2045-7634
Editore: John Wiley and Sons Ltd
DOI: 10.1002/cam4.4024

Liquid biopsy-based monitoring of residual disease in multiple myeloma by analysis of the rearranged immunoglobulin genes-A feasibility study.

Autori: Marx A, Osváth M, Szikora B, Pipek O, Csabai I, Nagy Á, Bödör C, Matula Z, Nagy G, Bors A, Uher F, Mikala G, Vályi-Nagy I, Kacskovics I.
Pubblicato in: PLoS One, 2023, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0285696

In Vitro Determination of Inhibitory Effects of Humic Substances Complexing Zn and Se on SARS-CoV-2 Virus Replication. Foods.

Autori: Hajdrik P, Pályi B, Kis Z, Kovács N, Veres DS, Szigeti K, Budán F, Hegedüs I, Kovács T, Bergmann R, Máthé D.
Pubblicato in: Foods, 2022, ISSN 2304-8158
Editore: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/foods11050694

Bafilomycin 1A Affects p62/SQSTM1 Autophagy Marker Protein Level and Autophagosome Puncta Formation Oppositely under Various Inflammatory Conditions in Cultured Rat Microglial Cells

Autori: István Pesti, Gábor Barczánfalvi, Karolina Dulka, Diana Kata, Eszter Farkas, Karoly Gulya
Pubblicato in: International Journal of Molecular Sciences, Numero 25, 2024, Pagina/e 8265, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms25158265

miR-21, miR-29a, and miR-106b: serum and tissue biomarkers with diagnostic potential in metastatic testicular cancer

Autori: Zsuzsanna Ujfaludi, Fruzsina Fazekas, Krisztina Biró, Orsolya Oláh-Németh, Istvan Buzogany, Farkas Sükösd, Tamás Beöthe, Tibor Pankotai
Pubblicato in: Scientific Reports, Numero 14, 2024, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-024-70552-x

Sodium–glucose cotransporter 2 inhibitors and the cancer patient: from diabetes to cardioprotection and beyond

Autori: Massimiliano Camilli, Marcello Viscovo, Luca Maggio, Alice Bonanni, Ilaria Torre, Claudio Pellegrino, Priscilla Lamendola, Lorenzo Tinti, Luciana Teofili, Stefan Hohaus, Gaetano Antonio Lanza, Peter Ferdinandy, Zoltan Varga, Filippo Crea, Antonella Lombardo, Giorgio Minotti
Pubblicato in: Basic Research in Cardiology, 2024, ISSN 1435-1803
Editore: D. Steinkopff-Verlag
DOI: 10.1007/s00395-024-01059-9

Beta-lactamase dependent and independent evolutionary paths to high-level ampicillin resistance

Autori: Rotem Gross, Idan Yelin, Viktória Lázár, Manoshi Sen Datta, Roy Kishony
Pubblicato in: Nature Communications, Numero 15, 2024, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-024-49621-2

Synergism of red blood cells and tranexamic acid in the inhibition of fibrinolysis.

Autori: Raska A, Kálmán K, Egri B, Csikós P, Beinrohr L, Szabó L, Tenekedjiev K, Nikolova N, Longstaff C, Roberts I, Kolev K, Wohner N.
Pubblicato in: Journal of Thrombosis and Haemostasis, 2023, ISSN 1538-7836
Editore: Wiley-Blackwell Publishing Ltd
DOI: 10.1016/j.jtha.2023.11.009

TRAF3 and NBR1 both influence the effect of the disease‐causing CYLD(Arg936X) mutation on NF‐κB activity

Autori: Judit Danis, Evelyn Kelemen, Neil Rajan, Nikoletta Nagy, Márta Széll, Éva Ádám
Pubblicato in: Experimental Dermatology, 2021, ISSN 0906-6705
Editore: Blackwell Publishing Inc.
DOI: 10.1111/exd.14365

Capturing time-dependent activation of genes and stress-response pathways using transcriptomics in iPSC-derived renal proximal tubule cells.

Autori: Jennings P, Carta G, Singh P, da Costa Pereira D, Feher A, Dinnyes A, Exner TE, Wilmes A.
Pubblicato in: Cell Biology and Toxicology, 2022, ISSN 0742-2091
Editore: Kluwer Academic Publishers
DOI: 10.1007/s10565-022-09783-5

Blue flash sheds light on the roles of individual phosphoserines in CFTR channel activation.

Autori: Csanády L.
Pubblicato in: Journal of General Physiology, 2023, ISSN 0022-1295
Editore: Rockefeller University Press
DOI: 10.1085/jgp.202313336

Cellular and Molecular Effects of SARS-CoV-2 Linking Lung Infection to the Brain

Autori: Linda Francistiová, Adrián Klepe, Géza Curley, Károly Gulya, András Dinnyés, Kata Filkor
Pubblicato in: Frontiers in Immunology, Numero 12, 2021, ISSN 1664-3224
Editore: Frontiers Media S.A.
DOI: 10.3389/fimmu.2021.730088

Extracellular Vesicle-Mediated Metastasis Suppressors NME1 and NME2 Modify Lipid Metabolism in Fibroblasts.

Autori: Mátyási B, Petővári G, Dankó T, Butz H, Likó I, Lőw P, Petit I, Bittar R, Bonnefont-Rousselot D, Farkas Z, Szeniczey T, Molnár K, Pálóczi K, Buzás EI, Boissan M, Sebestyén A, Takács-Vellai K.
Pubblicato in: Cancers, 2022, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14163913

Application of Lacunarity for Quantification of Single Molecule Localization Microscopy Images.

Autori: Kovács BBH, Varga D, Sebők D, Majoros H, Polanek R, Pankotai T, Hideghéty K, Kukovecz Á, Erdélyi M.
Pubblicato in: Cells, Numero 20734409, 2022, ISSN 2073-4409
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cells11193105

AIM2-driven inflammasome activation in heart failure

Autori: Zsófia Onódi, Mihály Ruppert, Dániel Kucsera, Alex Ali Sayour, Viktória E Tóth, Gábor Koncsos, Julianna Novák, Gábor B Brenner, András Makkos, Tamás Baranyai, Zoltán Giricz, Anikó Görbe, Przemyslaw Leszek, Mariann Gyöngyösi, Iván G Horváth, Rainer Schulz, Béla Merkely, Péter Ferdinandy, Tamás Radovits, Zoltán V Varga
Pubblicato in: Cardiovascular Research, 2021, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvab202

Suboptimal global transcriptional response increases the harmful effects of loss-of-function mutations

Autori: Károly Kovács, Zoltán Farkas, Djordje Bajić, Dorottya Kalapis, Andreea Daraba, Karola Almási, Bálint Kintses, Zoltán Bódi, Richard A Notebaart, Juan F Poyatos, Patrick Kemmeren, Frank C P Holstege, Csaba Pál, Balázs Papp
Pubblicato in: Molecular Biology and Evolution, 2020, ISSN 0737-4038
Editore: Oxford University Press
DOI: 10.1093/molbev/msaa280

Adenosine Promotes Human Hair Growth and Inhibits Catagen Transition In Vitro: Role of the Outer Root Sheath Keratinocytes

Autori: Erika Lisztes, Balázs István Tóth, Marta Bertolini, Imre Lőrinc Szabó, Nóra Zákány, Attila Oláh, Attila Gábor Szöllősi, Ralf Paus, Tamás Bíró
Pubblicato in: Journal of Investigative Dermatology, Numero 140/5, 2020, Pagina/e 1085-1088.e6, ISSN 0022-202X
Editore: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2019.08.456

The Phytocannabinoid (–)-Cannabidiol Operates as a Complex, Differential Modulator of Human Hair Growth: Anti-Inflammatory Submicromolar versus Hair Growth Inhibitory Micromolar Effects

Autori: Imre L. Szabó, Erika Lisztes, Gabriella Béke, Kinga Fanni Tóth, Ralf Paus, Attila Oláh, Tamás Bíró
Pubblicato in: Journal of Investigative Dermatology, Numero 140/2, 2019, ISSN 0022-202X
Editore: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2019.07.690

Endoplasmin Is a Hypoxia-Inducible Endoplasmic Reticulum-Derived Cargo of Extracellular Vesicles Released by Cardiac Cell Lines.

Autori: Koncz A, Turiák L, Németh K, Lenzinger D, Bárkai T, Lőrincz P, Zelenyánszki H, Vukman KV, Buzás EI, Visnovitz T.
Pubblicato in: Membranes, 2023, ISSN 2077-0375
Editore: Molecular Diversity Preservation International
DOI: 10.3390/membranes13040431

Nanotheranostic agents for neurodegenerative diseases

Autori: Parasuraman Padmanabhan, Mathangi Palanivel, Ajay Kumar, Domokos Máthé, George K. Radda, Kah-Leong Lim, Balázs Gulyás
Pubblicato in: Emerging Topics in Life Sciences, Numero 4/6, 2020, Pagina/e 645-675, ISSN 2397-8554
Editore: Portland Press
DOI: 10.1042/etls20190141

Cyclooxygenase-2 Modulates Glycosaminoglycan Production in the Skin During Salt Overload

Autori: Róbert Agócs, Domonkos Pap, Dániel Sugár, Gábor Tóth, Lilla Turiák, Zoltán Veréb, Lajos Kemény, Tivadar Tulassay, Ádám Vannay, Attila J. Szabó
Pubblicato in: Frontiers in Physiology, Numero 11, 2020, ISSN 1664-042X
Editore: Frontiers Research Foundation
DOI: 10.3389/fphys.2020.561722

Coordinated Cut and Bypass: Replication of Interstrand Crosslink-Containing DNA

Autori: Qiuzhen Li, Kata Dudás, Gabriella Tick, Lajos Haracska
Pubblicato in: Frontiers in Cell and Developmental Biology, Numero 9, 2021, ISSN 2296-634X
Editore: Frontiers Media S.A.
DOI: 10.3389/fcell.2021.699966

Manifestation of Triploid Heterosis in the Root System after Crossing Diploid and Autotetraploid Energy Willow Plants.

Autori: Dudits D, Cseri A, Török K, Vankova R, Dobrev PI, Sass L, Steinbach G, Kelemen-Valkony I, Zombori Z, Ferenc G, Ayaydin F.
Pubblicato in: Genes, 2023, ISSN 2073-4425
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes14101929

Cardioprotective efficacy of limb remote ischemic preconditioning in rats: discrepancy between meta-analysis and a three-centre in vivo study.

Autori: Sayour NV, Brenner GB, Makkos A, Kiss B, Kovácsházi C, Gergely TG, Aukrust SG, Tian H, Zenkl V, Gömöri K, Szabados T, Bencsik P, Heinen A, Schulz R, Baxter GF, Zuurbier CJ, Vokó Z, Ferdinandy P, Giricz Z.
Pubblicato in: Caridovascular Research, 2023, ISSN 0008-6363
Editore: Elsevier BV
DOI: 10.1093/cvr/cvad024

IBCL-222 Parallel Testing of Liquid Biopsy (ctDNA) and Tissue Biopsy Samples Yields Higher Frequency of EZH2 Mutations in Follicular Lymphoma.

Autori: Nagy Á, Bátai B, Gróf S, Kiss L, Balogh A, Mikala G, Király PA, Jóna Á, Demeter J, Masszi T, Masszi A, Schneider T, Bödör C.
Pubblicato in: Clin Lymphoma Myeloma Leuk., Numero 21522650, 2022, ISSN 2152-2650
Editore: Cancer Media Group
DOI: 10.1016/s2152-2650(22)01553-1

BC-miR: Monitoring Breast Cancer-Related miRNA Profile in Blood Sera-A Prosperous Approach for Tumor Detection.

Autori: Borsos BN, Páhi ZG, Ujfaludi Z, Sükösd F, Nikolényi A, Bankó S, Pankotai-Bodó G, Oláh-Németh O, Pankotai T.
Pubblicato in: Cells, 2022, ISSN 2073-4409
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cells11172721

Extracellular Vesicle-Based Communication May Contribute to the Co-Evolution of Cancer Stem Cells and Cancer-Associated Fibroblasts in Anti-Cancer Therapy

Autori: Gábor Valcz, Edit I. Buzás, Anna Sebestyén, Tibor Krenács, Zoltán Szállási, Péter Igaz, Béla Molnár
Pubblicato in: Cancers, Numero 12/8, 2020, Pagina/e 2324, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12082324

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

Autori: Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga
Pubblicato in: British Journal of Pharmacology, 2024, ISSN 0007-1188
Editore: Wiley-Blackwell
DOI: 10.1111/bph.16405

The Medial Septum as a Potential Target for Treating Brain Disorders Associated With Oscillopathies

Autori: Yuichi Takeuchi, Anett J. Nagy, Lívia Barcsai, Qun Li, Masahiro Ohsawa, Kenji Mizuseki, Antal Berényi
Pubblicato in: Frontiers in Neural Circuits, Numero 15, 2021, ISSN 1662-5110
Editore: Frontiers Research Foundation
DOI: 10.3389/fncir.2021.701080

Reducing cardiovascular risk in immune-mediated inflammatory diseases: Tumour necrosis factor inhibitors compared to conventional therapies-A systematic review and meta-analysis.

Autori: Galajda, N. Á., Meznerics, F. A., Mátrai, P., Fehérvári, P., Lengyel, A. S., Kolonics, M. V., Sipos, Z., Kemény, L. V., Csupor, D., Hegyi, P., Bánvölgyi, A., & Holló, P.
Pubblicato in: Journal of the European Academy of Dermatology and Venereology, 2024, ISSN 0926-9959
Editore: Elsevier BV
DOI: 10.1111/jdv.19900

Opportunities and challenges in studying the extracellular vesicle corona.

Autori: Buzas EI.
Pubblicato in: Nature Cell Biology, 2022, ISSN 1465-7392
Editore: Nature Publishing Group
DOI: 10.1038/s41556-022-00983-z

Investigating the influence of taurochenodeoxycholic acid (TCDCA) on pancreatic cancer cell behavior: An RNA sequencing approach

Autori: Eleonóra Gál, Shahram Parvaneh, Vanda Miklós, Péter Hegyi, Lajos Kemény, Zoltán Veréb, Viktória Venglovecz
Pubblicato in: Journal of Biotechnology, Numero 391, 2024, Pagina/e 20-32, ISSN 0168-1656
Editore: Elsevier BV
DOI: 10.1016/j.jbiotec.2024.05.010

Doxycycline prophylaxis for the prevention of sexually transmitted infections: A systematic review and meta-analysis of randomized controlled trials

Autori: István Szondy, Fanni Adél Meznerics, Kende Lőrincz, Lajos Vince Kemény, Anna Walter, Alzahra Ahmed Mohammed, Péter Hegyi, Norbert Kiss, András Bánvölgyi
Pubblicato in: International Journal of Infectious Diseases, Numero 147, 2024, Pagina/e 107186, ISSN 1201-9712
Editore: Elsevier BV
DOI: 10.1016/j.ijid.2024.107186

Comparative analysis of hippocampal extracellular space uncovers widely altered peptidome upon epileptic seizure in urethane-anaesthetized rats

Autori: Vanda Tukacs, Dániel Mittli, Éva Hunyadi-Gulyás, Zsuzsanna Darula, Gábor Juhász, József Kardos, Katalin Adrienna Kékesi
Pubblicato in: Fluids and Barriers of the CNS, Numero 21, 2024, ISSN 2045-8118
Editore: BioMed Central
DOI: 10.1186/s12987-024-00508-w

Genome-wide association study identifies susceptibility loci for acute myeloid leukemia

Autori: Wei-Yu Lin, Sarah E. Fordham, Eric Hungate, Nicola J. Sunter, Claire Elstob, Yaobo Xu, Catherine Park, Anne Quante, Konstantin Strauch, Christian Gieger, Andrew Skol, Thahira Rahman, Lara Sucheston-Campbell, Junke Wang, Theresa Hahn, Alyssa I. Clay-Gilmour, Gail L. Jones, Helen J. Marr, Graham H. Jackson, Tobias Menne, Mathew Collin, Adam Ivey, Robert K. Hills, Alan K. Burnett, Nigel H. Russell, J
Pubblicato in: Nature Communications, Numero 12/1, 2021, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-021-26551-x

Two Decades of Evolution of Our Understanding of the Transient Receptor Potential Melastatin 2 (TRPM2) Cation Channel

Autori: Andras Szollosi
Pubblicato in: Life, Numero 11/5, 2021, Pagina/e 397, ISSN 2075-1729
Editore: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/life11050397

Biocompatible poly(ethylene succinate) polyester with molecular weight dependent drug release properties.

Autori: Abdelghafour MM, Orbán Á, Deák Á, Lamch Ł, Frank É, Nagy R, Ziegenheim S, Sipos P, Farkas E, Bari F, Janovák L.
Pubblicato in: Biomaterials, 2022, ISSN 0142-9612
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.ijpharm.2022.121653

Temporally Targeted Interactions With Pathologic Oscillations as Therapeutical Targets in Epilepsy and Beyond.

Autori: Földi T, Lőrincz ML and Berényi
Pubblicato in: Frontiers in Neural Circuits, 2021, ISSN 1662-5110
Editore: Frontiers Research Foundation
DOI: 10.3389/fncir.2021.784085

Molecular imaging of bacterial outer membrane vesicles based on bacterial surface display.

Autori: Kövesdi D, Bősze S, Szabó I, Felföldi T, Oszwald E, Padmanabhan P, Gulyás BZ, Hamdani N, Máthé D, Varga Z, Szigeti K.
Pubblicato in: Scientific Reports, 2023, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-023-45628-9

Microenvironment shapes small-cell lung cancer neuroendocrine states and presents therapeutic opportunities

Autori: Parth Desai, Nobuyuki Takahashi, Rajesh Kumar, Samantha Nichols, Justin Malin, Allison Hunt, Christopher Schultz, Yingying Cao, Desiree Tillo, Darryl Nousome, Lakshya Chauhan, Linda Sciuto, Kimberly Jordan, Vinodh Rajapakse, Mayank Tandon, Delphine Lissa, Yang Zhang, Suresh Kumar, Lorinc Pongor, Abhay Singh, Brett Schroder, Ajit Kumar Sharma, Tiangen Chang, Rasa Vilimas, Danielle Pinkiert, Chante
Pubblicato in: Cell Reports Medicine, Numero 5, 2024, Pagina/e 101610, ISSN 2666-3791
Editore: Cell Press
DOI: 10.1016/j.xcrm.2024.101610

Multiple Layers of Complexity in O-Glycosylation Illustrated With the Urinary Glycoproteome.

Autori: Pap A, Kiraly IE, Medzihradszky KF, Darula Z.
Pubblicato in: Molecular and Cellular Proteomics, 2022, ISSN 1535-9476
Editore: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.mcpro.2022.100439

Intracellular Ca2+ Signalling in the Pathogenesis of Acute Pancreatitis: Recent Advances and Translational Perspectives

Autori: Petra Pallagi, Tamara Madácsy, Árpád Varga, József Maléth
Pubblicato in: International Journal of Molecular Sciences, Numero 21/11, 2020, Pagina/e 4005, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21114005

mulea: An R package for enrichment analysis using multiple ontologies and empirical false discovery rate

Autori: Cezary Turek, Márton Ölbei, Tamás Stirling, Gergely Fekete, Ervin Tasnádi, Leila Gul, Balázs Bohár, Balázs Papp, Wiktor Jurkowski, Eszter Ari
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MiR-128-3p as blood based liquid biopsy biomarker in childhood acute lymphoblastic leukemia.

Autori: Rzepiel A, Horváth A, Kutszegi N, Gézsi A, Sági JC, Almási L, Egyed B, Lőrincz P, Visnovitz T, Kovács GT, Szalai C, Semsei ÁF, Erdélyi DJ.
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Dry storage of mammalian spermatozoa and cells: state-of-the-art and possible future directions

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TFLink: an integrated gateway to access transcription factor-target gene interactions for multiple species.

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The Skin–Brain Axis: From UV and Pigmentation to Behaviour Modulation

Autori: Anna A. Ascsillán, Lajos V. Kemény
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Aflatoxin B1 Control by Various Pseudomonas Isolates

Autori: Dóra Anna Papp, Sándor Kocsubé, Zoltán Farkas, András Szekeres, Csaba Vágvölgyi, Zsuzsanna Hamari, Mónika Varga
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Ejection Fraction-Related Differences of Baseline Characteristics and Outcomes in Troponin-Positive Patients without Obstructive Coronary Artery Disease

Autori: Mustafa Kacmaz, Clara Schlettert, Fabienne Kreimer, Mohammad Abumayyaleh, Ibrahim Akin, Andreas Mügge, Assem Aweimer, Nazha Hamdani, Ibrahim El-Battrawy
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Predicting immune checkpoint therapy response in three independent metastatic melanoma cohorts

Autori: Leticia Szadai, Aron Bartha, Indira Pla Parada, Alexandra I.T. Lakatos, Dorottya M.P. Pál, Anna Sára Lengyel, Natália Pinto de Almeida, Ágnes Judit Jánosi, Fábio Nogueira, Beata Szeitz, Viktória Doma, Nicole Woldmar, Jéssica Guedes, Zsuzsanna Ujfaludi, Zoltán Gábor Pahi, Tibor Pankotai, Yonghyo Kim, Balázs Győrffy, Bo Baldetorp, Charlotte Welinder, A. Marcell Szasz, Lazaro Betancourt,
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Tumour Necrosis Factor Alpha-induced Protein 3 Negatively Regulates Cutibacterium acnes-induced Innate Immune Events in Epidermal Keratinocytes

Autori: Lilla Erdei, Beáta Szilvia Bolla, Renáta Bozó, Gábor Tax, Edit Urbán, Katalin Burián, Lajos Kemény, Kornélia Szabó
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Molecular characterization of immune checkpoint inhibitor-induced cardiotoxicity reveals IL-17A as a driver of cardiac dysfunction after anti-PD-1 treatment.

Autori: Gergely TG, Kucsera D, Tóth VE, Kovács T, Sayour NV, Drobni ZD, Ruppert M, Petrovich B, Ágg B, Onódi Z, Fekete N, Pállinger É, Buzás EI, Yousif LI, Meijers WC, Radovits T, Merkely B, Ferdinandy P, Varga ZV.
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Two-year event-free survival prediction in DLBCL patients based on in vivo radiomics and clinical parameters,

Autori: Zsombor Ritter, Laszlo Papp, Katalin Zámbó, Zoltan Tóth, Dániel Dezso, Dániel Sándor Veres, Domokos Máthé, Ferenc Budán, Éva Karádi, Anett Balikó, László Pajor, Árpád Szomor, Erzsébet Schmidt, Hussain Alizadeh
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Ca2+/calmodulin-dependent protein kinase II and protein kinase G oxidation contributes to impaired sarcomeric proteins in hypertrophy model.

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Could basement membrane alterations, resembling micro‐wounds at the dermo‐epidermal junction in psoriatic non‐lesional skin, make the skin susceptible to lesion formation?

Autori: Renáta Bozó, Lili Borbála Flink, Nóra Belső, Barbara Gubán, Márta Széll, Lajos Kemény, Zsuzsanna Bata‐Csörgő
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Gyermekkori agydaganatok: diagnózis és terápia – komprehenzív genomikai profilozás [Childhood brain tumors: diagnosis and therapy - comprehensive genomic profiling].

Autori: Brückner E, Bedics G, Reiniger L, Rajnai H, Jakab Z, Bödör C, Scheich B, Garami M.
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Gene loss and compensatory evolution promotes the emergence of morphological novelties in budding yeast

Autori: Farkas Z, Kovács K, Sarkadi Z, Kalapis D, Fekete G, Birtyik F, Ayaydin F, Molnár C, Horváth P, Pál C, Papp B.
Pubblicato in: Nature Ecology and Evolution, 2022, ISSN 2397-334X
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Distinct miRNA Expression Signatures of Primary and Secondary Central Nervous System Lymphomas.

Autori: Sebestyén E, Nagy Á, Marosvári D, Rajnai H, Kajtár B, Deák B, Matolcsy A, Brandner S, Storhoff J, Chen N, Bagó AG, Bödör C, Reiniger L.
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Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells

Autori: Roman C. Sarott, Matthias V. Westphal, Patrick Pfaff, Claudia Korn, David A. Sykes, Thais Gazzi, Benjamin Brennecke, Kenneth Atz, Marie Weise, Yelena Mostinski, Pattarin Hompluem, Eline Koers, Tamara Miljuš, Nicolas J. Roth, Hermon Asmelash, Man C. Vong, Jacopo Piovesan, Wolfgang Guba, Arne C. Rufer, Eric A. Kusznir, Sylwia Huber, Catarina Raposo, Elisabeth A. Zirwes, Anja Osterwald, Anto Pavlovi
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Editore: American Chemical Society
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FTO Intronic SNP Strongly Influences Human Neck Adipocyte Browning Determined by Tissue and PPARγ Specific Regulation: A Transcriptome Analysis

Autori: Beáta B. Tóth, Rini Arianti, Abhirup Shaw, Attila Vámos, Zoltán Veréb, Szilárd Póliska, Ferenc Győry, Zsolt Bacso, László Fésüs, Endre Kristóf
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A series of xanthenes inhibiting Rad6 function and Rad6-Rad18 interaction in the PCNA ubiquitination cascade.

Autori: Fenteany G, Sharma G, Gaur P, Borics A, Wéber E, Kiss E, Haracska L.
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Evidence of a Myenteric Plexus Barrier and its Macrophage-Dependent Degradation during Murine Colitis: Implications in Enteric Neuroinflammation

Autori: David Dora, Szilamer Ferenczi, Rhian Stavely, Viktoria E. Toth, Zoltan V. Varga, Tamas Kovacs, Ildiko Bodi, Ryo Hotta, Krisztina J. Kovacs, Allan M. Goldstein, Nandor Nagy
Pubblicato in: Cellular and Molecular Gastroenterology and Hepatology, 2021, ISSN 2352-345X
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Development of Polymer-Encapsulated, Amine-Functionalized Zinc Ferrite Nanoparticles as MRI Contrast Agents.

Autori: Ilosvai ÁM, Forgách L, Kovács N, Heydari F, Szigeti K, Máthé D, Kristály F, Daróczi L, Kaleta Z, Viskolcz B, Nagy M, Vanyorek L.
Pubblicato in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
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Effect of hypercholesterolemia on circulating and cardiomyocyte-derived extracellular vesicles

Autori: Csenger Kovácsházi, Szabolcs Hambalkó, Nabil V. Sayour, Tamás G. Gergely, Gábor B. Brenner, Csilla Pelyhe, Dóra Kapui, Bennet Y. Weber, Alexander L. Hültenschmidt, Éva Pállinger, Edit I. Buzás, Ádám Zolcsák, Bálint Kiss, Tamás Bozó, Csilla Csányi, Nikolett Kósa, Miklós Kellermayer, Róbert Farkas, Gellért B. Karvaly, Kieran Wynne, David Matallanas, Péter Ferdinandy, Zoltán Gi
Pubblicato in: Scientific Reports, Numero 14, 2024, ISSN 2045-2322
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Effects of bowel cleansing on the composition of the gut microbiota in inflammatory bowel disease patients and healthy controls.

Autori: Bacsur P, Rutka M, Asbóth A, Resál T, Szántó K, Jójárt B, Bálint A, Ari E, Ajibola W, Kintses B, Fehér T, Pigniczki D, Bor R, Fábián A, Maléth J, Szepes Z, Farkas K, Molnár T.
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Mechanisms of myocardial reverse remodelling and its clinical significance: A scientific statement of the ESC Working Group on Myocardial Function

Autori: Inês Falcão‐Pires, Ana Filipa Ferreira, Fábio Trindade, Luc Bertrand, Michele Ciccarelli, Valeria Visco, Dana Dawson, Nazha Hamdani, Linda W. Van Laake, Frank Lezoualc'h, Wolfgang A. Linke, Ida G Lunde, Peter P. Rainer, Mahmoud Abdellatif, Jolanda Van der Velden, Nicola Cosentino, Alessia Paldino, Giulio Pompilio, Serena Zacchigna, Stephane Heymans, Thomas Thum, Carlo Gabriele Tocchetti
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Endoplasmic Reticulum‐Plasma Membrane Contact Sites as an Organizing Principle for Compartmentalized Calcium and cAMP Signaling

Autori: Tim Crul, József Maléth
Pubblicato in: International Journal of Molecular Sciences, Numero 22/9, 2021, Pagina/e 4703, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
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Sarcoma_CellminerCDB: A tool to interrogate the genomic and functional characteristics of a comprehensive collection of sarcoma cell lines.

Autori: Tlemsani, C., Heske, C. M., Elloumi, F., Pongor, L., Khandagale, P., Varma, S., Meltzer, P. S., Khan, J., Reinhold, Wi. C., Pommier, Y.
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Dual amplification strategy turns TRPM2 channels into supersensitive central heat detectors.

Autori: Bartók Á, Csanády L.
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Editore: National Academy of Sciences
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Deciphering of Candida parapsilosis induced immune response in Drosophila melanogaster

Autori: Katalin Csonka, Zsolt Tasi, Viktor Vedelek, Csaba Vágvölgyi, Rita Sinka, Attila Gácser
Pubblicato in: Virulence, Numero 12/1, 2021, Pagina/e 2571-2582, ISSN 2150-5594
Editore: Landes Bioscience
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A novel BRET-Based GAP assay reveals phosphorylation-dependent regulation of the RAC-specific GTPase activating protein ARHGAP25.

Autori: Wisniewski É, Czárán D, Kovács F, Bahurek E, Németh A, Sasvári P, Szanda G, Pettkó-Szandtner A, Klement E, Ligeti E, Csépányi-Kömi R.
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Editore: Federation of American Societies for Experimental Biology
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Case Report: Development of Diffuse Large B Cell Lymphoma a Long Time After Hairy Cell Leukemia.

Autori: Nagy ZF, Ferenczi K, Istenes I, Eid H, Bödör C, Timár B, Demeter J.
Pubblicato in: Pathology and Oncology Research, 2022, ISSN 1532-2807
Editore: Frontiers Media S.A.
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Recipient Pericardial Apolipoprotein Levels Might Be an Indicator of Worse Outcomes after Orthotopic Heart Transplantation.

Autori: Székely, A., Pállinger, É., Töreki, E., Ifju, M., Barta, B. A., Szécsi, B., Losoncz, E., Dohy, Z., Barabás, I. J., Kosztin, A., Buzas, E. I., Radovits, T., & Merkely, B.
Pubblicato in: International journal of molecular sciences, 2024, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
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Inflammasome Activity in the Skeletal Muscle and Heart of Rodent Models for Duchenne Muscular Dystrophy. Int J Mol Sci. 2023 May 9;24(10):8497.

Autori: Onódi Z, Szabó PL, Kucsera D, Pokreisz P, Dostal C, Hilber K, Oudit GY, Podesser BK, Ferdinandy P, Varga ZV, Kiss A.
Pubblicato in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
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Commentary on ‘Sebocyte differentiation as a new target for acne therapy: an in vivo experience’

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Lectin-Based Immunophenotyping and Whole Proteomic Profiling of CT-26 Colon Carcinoma Murine Model.

Autori: Faragó, A., Zvara, Á., Tiszlavicz, L., Hunyadi-Gulyás, É., Darula, Z., Hegedűs, Z., Szabó, E., Surguta, S. E., Tóvári, J., Puskás, L. G., & Szebeni, G. J.
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Rapid Evolution of Reduced Susceptibility against a Balanced Dual-Targeting Antibiotic through Stepping-Stone Mutations

Autori: Petra Szili, Gábor Draskovits, Tamás Révész, Ferenc Bogár, Dávid Balogh, Tamás Martinek, Lejla Daruka, Réka Spohn, Bálint Márk Vásárhelyi, Márton Czikkely, Bálint Kintses, Gábor Grézal, Györgyi Ferenc, Csaba Pál, Ákos Nyerges
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Applied models and molecular characteristics of small cell lung cancer. Pathology and Oncology Research

Autori: Fűr, G. M., Nemes, K., Magó, É., Benő, A. Á., Topolcsányi, P., Moldvay, J., Pongor, L. S.
Pubblicato in: Pathology and Oncology Research, 2024, ISSN 1219-4956
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Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes.

Autori: Casado P, Rio-Machin A, Miettinen JJ, Bewicke-Copley F, Rouault-Pierre K, Krizsan S, Parsons A, Rajeeve V, Miraki-Moud F, Taussig DC, Bödör C, Gribben J, Heckman C, Fitzgibbon J, Cutillas PR.
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Local laboratory-run donor-derived cell-free DNA assay for rejection surveillance in heart transplantation-first six months of clinical experience.

Autori: Teszak T, Bödör C, Hegyi L, Levay L, Nagy B, Fintha A, Merkely B, Sax B.
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Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches.

Autori: Welsh, J. A., Goberdhan, D. C. I., O'Driscoll, L., Buzas, E. I., Blenkiron, C., Bussolati, B., Cai, H., Di Vizio, D., Driedonks, T. A. P., Erdbrügger, U., Falcon-Perez, J. M., Fu, Q. L., Hill, A. F., Lenassi, M., Lim, S. K., Mahoney, M. G., Mohanty, S., Möller, A., Nieuwland, R., Ochiya, T., … Witwer, K. W.
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Co-Detection of VEGF-A and Its Regulator, microRNA-181a, May Indicate Central Nervous System Involvement in Pediatric Leukemia

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Pubblicato in: Pathology and Oncology Research, 2022, ISSN 1219-4956
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Amino Acid Polymorphisms in the VHIID Conserved Motif of Nodulation Signaling Pathways 2 Distinctly Modulate Symbiotic Signaling and Nodule Morphogenesis in Medicago truncatula.

Autori: Kovacs S, Fodor L, Domonkos A, Ayaydin F, Laczi K, Rákhely G and Kalo P
Pubblicato in: Frontiers in plant science, 2021, ISSN 1664-462X
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Age-Related Inflammatory Balance Shift, Nasal Barrier Function, and Cerebro-Morphological Status in Healthy and Diseased Rodents

Autori: Zsófia Varga-Medveczky, Noémi Kovács, Melinda E. Tóth, Miklós Sántha, Ildikó Horváth, Luca Anna Bors, Katalin Fónagy, Timea Imre, Pál Szabó, Domokos Máthé, Franciska Erdő
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Emerging human pulmonary dirofilariasis in Hungary: a single center experience

Autori: Levente Kuthi, Tamás Zombori, László Tiszlavicz, Fanni Hegedűs, Szintia Almási, Bence Baráth, Mohammed Almakrami, Mohammad Jamal EJ, Nikolett Barta, Zsuzsanna Ujfaludi, Tibor Pankotai, Adrienn Hajdu, József Furák, Anita Sejben
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Bile acid- and ethanol-mediated activation of Orai1 damages pancreatic ductal secretion in acute pancreatitis.

Autori: Pallagi P, Görög M, Papp N, Madácsy T, Varga Á, Crul T, Szabó V, Molnár M, Dudás K, Grassalkovich A, Szederkényi E, Lázár G, Venglovecz V, Hegyi P, Maléth J.
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Hepatocyte vitamin D receptor functions as a nutrient sensor that regulates energy storage and tissue growth in zebrafish

Autori: Scott H. Freeburg, Arkadi Shwartz, Lajos V. Kemény, Colton J. Smith, Olivia Weeks, Bess M. Miller, Nadia PenkoffLidbeck, David E. Fisher, Kimberley J. Evason, Wolfram Goessling
Pubblicato in: Cell Reports, Numero 43, 2024, Pagina/e 114393, ISSN 2211-1247
Editore: Cell Press
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Saxagliptin Cardiotoxicity in Chronic Heart Failure: The Role of DPP4 in the Regulation of Neuropeptide Tone.

Autori: Vörös I, Onódi Z, Tóth VÉ, Gergely TG, Sághy É, Görbe A, Kemény Á, Leszek P, Helyes Z, Ferdinandy P, Varga ZV.
Pubblicato in: Biomedicines, 2022, ISSN 2227-9059
Editore: MDPI AG
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BC-Monitor: Towards a Routinely Accessible Circulating Tumor DNA-Based Tool for Real-Time Monitoring Breast Cancer Progression and Treatment Effectiveness

Autori: Katalin Priskin, Sára Pólya, Lajos Pintér, Gábor Jaksa, Bernadett Csányi, Márton Zsolt Enyedi, Eszter Sági-Zsigmond, Farkas Sükösd, Orsolya Oláh-Németh, Gyöngyi Kelemen, Alíz Nikolényi, Gabriella Uhercsák, Dóra Sántha, Ágnes Dobi, Éva Szilágyi, Erzsébet Valicsek, László Tordai, Rozália Tóth, Zsuzsanna Kahán, Lajos Haracska
Pubblicato in: Cancers, Numero 13/14, 2021, Pagina/e 3489, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
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Impacts of gene variants on drug effects-the foundation of genotype-guided pharmacologic therapy for long QT syndrome and short QT syndrome

Autori: Zhihan Zhao, Xiaobiao Zang, Kerun Niu, Weifeng Song, Xianqing Wang, Andreas Mügge, Assem Aweimer, Nazha Hamdani, Xiaobo Zhou, Yonghui Zhao, Ibrahim Akin, Ibrahim El-Battrawy
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GATA2 deficiency and MDS/AML: Experimental strategies for disease modelling and future therapeutic prospects.

Autori: Kotmayer L, Romero-Moya D, Marin-Bejar O, Kozyra E, Català A, Bigas A, Wlodarski MW, Bödör C, Giorgetti A.
Pubblicato in: British Journal of Haematology, 2022, ISSN 0007-1048
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Spreading depolarization causes reperfusion failure after cerebral ischemia.

Autori: Törteli A, Tóth R, Berger S, Samardzic S, Bari F, Menyhárt Á, Farkas E.
Pubblicato in: Journal of Cerebral Blood Flow and Metabolism, 2023, ISSN 0271-678X
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Toll-like receptor 4 (TLR4) is the major pattern recognition receptor triggering the protective effect of a <i>Candida albicans</i> extracellular vesicle-based vaccine prototype in murine systemic candidiasis

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Autori: Apjok G, Számel M, Christodoulou C, Seregi V, Vásárhelyi BM, Stirling T, Eszenyi B, Sári T, Vidovics F, Nagrand E, Kovács D, Szili P, Lantos II, Méhi O, Jangir PK, Herczeg R, Gálik B, Urbán P, Gyenesei A, Draskovits G, Nyerges Á, Fekete G, Bodai L, Zsindely N, Dénes B, Yosef I, Qimron U, Papp B, Pál C, Kintses B.
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Autori: Eleonóra Gál, Zoltán Veréb, Lajos Kemény, Dávid Rakk, András Szekeres, Eszter Becskeházi, László Tiszlavicz, Tamás Takács, László Czakó, Péter Hegyi, Viktória Venglovecz
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Autori: Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, Eva Pinto Jurado, Siham Zentout, Alexandra Mihuţ, Anna Georgina Kopasz, Mihály Mérey, Rebecca Smith, Abhishek Bharadwaj Sharma, Nicholas D Lakin, Andrew James Bowman, Lajos Haracska, Sébastien Huet, Gyula Timinszky
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Werner helicase interacting protein 1 contributes to G-quadruplex processing in human cells

Autori: Lili Hegedus, Agnes Toth, Gabor M. Harami, Janos Palinkas, Nargis Karatayeva, Eniko Sajben-Nagy, Szabolcs Bene, Sara Afzali Jaktajdinani, Mihaly Kovacs, Szilvia Juhasz, Peter Burkovics
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Chloroplast phosphate transporter CrPHT4-7 regulates phosphate homeostasis and photosynthesis in Chlamydomonas.

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Insights into the Structure of Comirnaty Covid-19 Vaccine: A Theory on Soft, Partially Bilayer-Covered Nanoparticles with Hydrogen Bond-Stabilized mRNA-Lipid Complexes.

Autori: Szebeni J, Kiss B, Bozó T, Turjeman K, Levi-Kalisman Y, Barenholz Y, Kellermayer M.
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Nanofiber formation as a promising technology for preservation and easy storage of extracellular vesicles.

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Proteome-wide landscape of solubility limits in a bacterial cell.

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Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling.

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Epigenome profiling reveals aberrant DNA methylation signature in GATA2 deficiency.

Autori: Marin-Bejar O, Romero-Moya D, Rodriguez-Ubreva J, Distefano M, Lessi F, Aretini P, Liquori A, Castaño J, Kozyra E, Kotmayer L, Bueno C, Cervera J, Rodriguez-Gallego JC, Nomdedeu JF, Murillo-Sanjuán L, De Heredia CD, Pérez-Martinez A, López-Cadenas F, Martínez-Laperche C, Dorado-Herrero N, Marco FM, Prósper F, Menendez P, Valcárcel D, Ballestar E, Bödör C, Bigas A, Catalá A, Wlodarski MW,
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PCSK9 in Myocardial Infarction and Cardioprotection: Importance of Lipid Metabolism and Inflammation

Autori: Ioanna Andreadou, Maria Tsoumani, Gemma Vilahur, Ignatios Ikonomidis, Lina Badimon, Zoltán V. Varga, Péter Ferdinandy, Rainer Schulz
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Suppression of Metastatic Melanoma Growth in Lung by Modulated Electro-Hyperthermia Monitored by a Minimally Invasive Heat Stress Testing Approach in Mice

Autori: Mbuotidem Jeremiah Thomas, Enikő Major, Anett Benedek, Ildikó Horváth, Domokos Máthé, Ralf Bergmann, Attila Marcell Szász, Tibor Krenács, Zoltán Benyó
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Autori: Pálóczi K, Buzas EI, Falus A.
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Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions.

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Platelet-Rich Plasma in Chronic Wound Management: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.

Autori: Meznerics FA, Fehérvári P, Dembrovszky F, Kovács KD, Kemény LV, Csupor D, Hegyi P, Bánvölgyi A.
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Editorial: Cardiovascular sequelae of chemotherapy and radiotherapy in cancer survivors: current evidence and perspectives. Front Cardiovasc Med. 2023 Jun 20;10:1230862.

Autori: Felici T, Skinner R, Ferdinandy P, Varga ZV, Lombardo A, Camilli M.
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Psoriasis-Associated Inflammatory Conditions Induce IL-23 mRNA Expression in Normal Human Epidermal Keratinocytes.

Autori: Kelemen E, Ádám É, Sági SM, Göblös A, Kemény L, Bata-Csörgő Z, Széll M, Danis J.
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Bedics G, Kotmayer L, Zajta E, Hegyi LL, Brückner EÁ, Rajnai H, Reiniger L, Bödör C, Garami M, Scheich B.

Autori: Germline MUTYH mutations and high-grade gliomas: novel evidence for a potential association
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Topography, Spike Dynamics, and Nanomechanics of Individual Native SARS-CoV-2 Virions

Autori: Bálint Kiss, Zoltán Kis, Bernadett Pályi, Miklós S. Z. Kellermayer
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Predicting drug response of small cell lung cancer cell lines based on enrichment analysis of complex gene signatures.

Autori: Nemes, K., Benő, A., Topolcsányi, P., Magó, É., Fűr, G. M., & Pongor, L. Ő. S.
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The Medicago truncatula nodule-specific cysteine-rich peptides, NCR343 and NCR-new35 are required for the maintenance of rhizobia in nitrogen-fixing nodules.

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TRPM2 - An adjustable thermostat.

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STABILON, a Novel Sequence Motif That Enhances the Expression and Accumulation of Intracellular and Secreted Proteins.

Autori: Rethi-Nagy Z, Abraham E, Udvardy K, Klement E, Darula Z, Pal M, Katona RL, Tubak V, Pali T, Kota Z, Sinka R, Udvardy A, Lipinszki Z.
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Human pancreatic ductal organoids with controlled polarity provide a novel ex vivo tool to study epithelial cell physiology.

Autori: Varga Á, Madácsy T, Görög M, Kiss A, Susánszki P, Szabó V, Jójárt B, Dudás K, Farkas G Jr, Szederkényi E, Lázár G, Farkas A, Ayaydin F, Pallagi P, Maléth J.
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Closed-loop stimulation of the medial septum terminates epileptic seizures

Autori: Yuichi Takeuchi, Márk Harangozó, Lizeth Pedraza, Tamás Földi, Gábor Kozák, Qun Li, Antal Berényi
Pubblicato in: Brain, 2021, ISSN 0006-8950
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The Small Heat Shock Protein, HSPB1, Interacts with and Modulates the Physical Structure of Membranes

Autori: Csoboz B, Gombos I, Kóta Z, Dukic B, Klement É, Varga-Zsíros V, Lipinszki Z, Páli T, Vígh L, Török Z.
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Improvement of lidocaine skin permeation by using passive and active enhancer methods

Autori: Feria Hasanpour, Mária Budai-Szűcs, Anita Kovács, Rita Ambrus, Orsolya Jójárt-Laczkovich, Martin Cseh, Zsolt Geretovszky, Ferhan Ayaydin, Szilvia Berkó
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The 3M Concept: Biomedical Translational Imaging from Molecules to Mouse to Man

Autori: Domokos Máthé, Bálint Kiss, Bernadett Pályi, Zoltán Kis, László Forgách, Nikolett Hegedűs, Zoltán Varga, Krisztián Szigeti, Kinga Karlinger, Miklós S Z Kellermayer
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An implanted device enables in vivo monitoring of extracellular vesicle‐mediated spread of pro‐inflammatory mast cell response in mice

Autori: Krisztina V. Vukman, Andrea Ferencz, Daniella Fehér, Krisztina Juhos, Péter Lőrincz, Tamás Visnovitz, Anna Koncz, Krisztina Pálóczi, Gábor Seregélyes, András Försönits, Delaram Khamari, Alicia Galinsoga, László Drahos, Edit I. Buzás
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Low-burden TP53 mutations represent frequent genetic events in CLL with an increased risk for treatment initiation.

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Diagnostic and Therapeutic Challenges in Severe Peristomal Pyoderma Gangrenosum

Autori: Bernadett Farkas, Emese Ivány, Anita Bálint, Peter Bacsur, Tamás Molnár, Klaudia Farkas
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Cardiac damage and tropism of severe acute respiratory syndrome coronavirus 2.

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Single-Cell Sequencing: Biological Insight and Potential Clinical Implications in Pediatric Leukemia

Autori: Donát Alpár, Bálint Egyed, Csaba Bödör, Gábor T. Kovács
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Protein Kinase D3 (PKD3) Requires Hsp90 for Stability and Promotion of Prostate Cancer Cell Migration.

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The RUNX1 Database (RUNX1db): establishment of an expert curated RUNX1 registry and genomics database as a public resource for familial platelet disorder with myeloid malignancy

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Formation of a protein corona on the surface of extracellular vesicles in blood plasma

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Rational design of balanced dual-targeting antibiotics with limited resistance

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A Randomized Controlled Trial with a Medical Device Containing Sodium Hyaluronate and Nicotinic Acid to Increase the Efficacy of Ultraviolet Phototherapy in Psoriasis

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Autori: Gergely, T. G., Drobni, Z. D., Kallikourdis, M., Zhu, H., Meijers, W. C., Neilan, T. G., Rassaf, T., Ferdinandy, P., & Varga, Z. V.
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Autori: Heger J, Partsch S, Harjung C, Varga ZV, Baranyai T, Weiß J, Kremer L, Locquet F, Leszek P, Ágg B, Benczik B, Ferdinandy P, Schulz R, Euler G
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The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ

Autori: Xuexin Li, Ivó Hernandez, Seda Koyuncu, Balázs Kis, Maria Häggblad, Louise Lidemalm, Anna A. Abbas, Sramkó Bendegúz, Anikó Göblös, Lars Brautigam, Jose J. Lucas, Jordi Carreras-Puigvert, Daniela Hühn, Karolina Pircs, David Vilchez, Oscar Fernandez-Capetillo
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Autori: Tibor Novák, Dániel Varga, Péter Bíró, Bálint Barna H. Kovács, Hajnalka Majoros, Tibor Pankotai, Szilárd Szikora.
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Male and Female Animals Respond Differently to High-Fat Diet and Regular Exercise Training in a Mouse Model of Hyperlipidemia

Autori: Melinda E. Tóth, Brigitta Dukay, Mária Péter, Gábor Balogh, Gergő Szűcs, Ágnes Zvara, Gábor J. Szebeni, Petra Hajdu, Márta Sárközy, László G. Puskás, Zsolt Török, Tamás Csont, László Vígh, Miklós Sántha
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The Effect of Molecular Weight on the Solubility Properties of Biocompatible Poly(ethylene succinate) Polyester

Autori: Mohamed M. Abdelghafour, Ágoston Orbán, Ágota Deák, Łukasz Lamch, Éva Frank, Roland Nagy, Adél Ádám, Pál Sipos, Eszter Farkas, Ferenc Bari, László Janovák
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Autori: Anita Bálint, Klaudia Farkas, Orsolya Méhi, Bálint Kintses, Bálint Márk Vásárhelyi, Eszter Ari, Csaba Pál, Tamara Madácsy, József Maléth, Kata Judit Szántó, István Nagy, Mariann Rutka, Péter Bacsur, Diána Szűcs, Zoltán Szepes, Ferenc Nagy, Anna Fábián, Renáta Bor, Ágnes Milassin, Tamás Molnár
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Cutibacterium acnes regulates the epidermal barrier properties of HPV-KER human immortalized keratinocyte cultures

Autori: Beáta Szilvia Bolla, Lilla Erdei, Edit Urbán, Katalin Burián, Lajos Kemény, Kornélia Szabó
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The Impact of Body Mass Index on the Mortality of Myocardial Infarction Patients With Nonobstructive Coronary Arteries

Autori: Chaohui Dong, Mustafa Kacmaz, Clara Schlettert, Mohammad Abumayyaleh, Ibrahim Akin, Rayyan Hemetsberger, Andreas Mügge, Assem Aweimer, Nazha Hamdani, Ibrahim El‐Battrawy
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New targets and indications for probenecid.

Autori: Onódi Z, Koch S, Rubinstein J, Ferdinandy P, Varga ZV.
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Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe.

Autori: Gazzi T, Brennecke B, Atz K, Korn C, Sykes D, Forn-Cuni G, Pfaff P, Sarott RC, Westphal MV, Mostinski Y, Mach L, Wasinska-Kalwa M, Weise M, Hoare BL, Miljuš T, Mexi M, Roth N, Koers EJ, Guba W, Alker A, Rufer AC, Kusznir EA, Huber S, Raposo C, Zirwes EA, Osterwald A, Pavlovic A, Moes S, Beck J, Nettekoven M, Benito-Cuesta I, Grande T, Drawnel F, Widmer G, Holzer D, van der Wel T, Mandhair H, Hone
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Editore: Royal Society of Chemistry
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ING1 inhibits Twist1 expression to block EMT and is antagonized by the HDAC inhibitor vorinostat.

Autori: Yang Y, Ma B, Djamshidi M, Zhang Q, Sarkar A, Chanda A, Tran U, Soh J, Sandall C, Chen HM, MacDonald JA, Bonni S, Sensen CW, Zheng J, Riabowol K.
Pubblicato in: European Journal of Cell Biology, 2023, ISSN 1618-1298
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Protein Kinase D Plays a Crucial Role in Maintaining Cardiac Homeostasis by Regulating Post-Translational Modifications of Myofilament Proteins.

Autori: Herwig, M., Begovic, M., Budde, H., Delalat, S., Zhazykbayeva, S., Sieme, M., Schneider, L., Jaquet, K., Mügge, A., Akin, I., El-Battrawy, I., Fielitz, J., & Hamdani, N.
Pubblicato in: International journal of molecular sciences, 2024, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
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Grafted human induced pluripotent stem cells improve the outcome of spinal cord injury: modulation of the lesion microenvironment

Autori: Tamás Bellák, Zoltán Fekécs, Dénes Török, Zsuzsanna Táncos, Csilla Nemes, Zsófia Tézsla, László Gál, Suchitra Polgári, Julianna Kobolák, András Dinnyés, Antal Nógrádi, Krisztián Pajer
Pubblicato in: Scientific Reports, Numero 10/1, 2020, ISSN 2045-2322
Editore: Nature Publishing Group
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Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41.

Autori: Homan CC, Drazer MW, Yu K, Lawrence DM, Feng J, Arriola-Martinez L, Pozsgai MJ, McNeely KE, Ha T, Venugopal P, Arts P, King-Smith SL, Cheah J, Armstrong M, Wang P, Bödör C, Cantor AB, Cazzola M, Degelman E, DiNardo CD, Duployez N, Favier R, Fröhling S, Rio-Machin A, Klco JM, Krämer A, Kurokawa M, Lee J, Malcovati L, Morgan NV, Natsoulis G, Owen C, Patel KP, Preudhomme C, Raslova H, Rienhoff H,
Pubblicato in: Blood Advances, 2023, ISSN 2473-9529
Editore: Elsevier
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SerpinB10, a Serine Protease Inhibitor, Is Implicated in UV-Induced Cellular Response

Autori: Hajnalka Majoros, Barbara N. Borsos, Zsuzsanna Ujfaludi, Zoltán G. Páhi, Mónika Mórocz, Lajos Haracska, Imre Miklós Boros, Tibor Pankotai
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Editore: Multidisciplinary Digital Publishing Institute (MDPI)
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Regenerative Neurology and Regenerative Cardiology: Shared Hurdles and Achievements

Autori: Mitrečić D, Hribljan V, Jagečić D, Isaković J, Lamberto F, Horánszky A, Zana M, Foldes G, Zavan B, Pivoriūnas A, Martinez S, Mazzini L, Radenovic L, Milasin J, Chachques JC, Buzanska L, Song MS, Dinnyés A.
Pubblicato in: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
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Chronic treatment with rofecoxib but not ischemic preconditioning of the myocardium ameliorates early intestinal damage following cardiac ischemia/reperfusion injury in rats

Autori: Szilvia B. László, Bernadette Lázár, Gábor B. Brenner, András Makkos, Mihály Balogh, Mahmoud Al-Khrasani, Barbara Hutka, Amir Mohammadzadeh, Ágnes Kemény, Terézia László, Bálint Scheich, Tamara Szabados, Éva Kenyeres, Zoltán Giricz, Péter Bencsik, Zoltán V. Varga, Julianna Novák, Zsuzsanna Helyes, Péter Ferdinandy, Klára Gyires, Zoltán S. Zádori
Pubblicato in: Biochemical Pharmacology, Numero 178, 2020, Pagina/e 114099, ISSN 0006-2952
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<scp>PDE9A</scp> Inhibition Improves Coronary Microvascular Rarefaction and Left Ventricular Diastolic Dysfunction in the <scp>ZSF1</scp> Rat Model of <scp>HFpEF</scp>

Autori: Katie Anne Fopiano, Saltanat Zhazykbayeva, Ibrahim El‐Battrawy, Vadym Buncha, William M. Pearson, Davis J. Hardell, Liwei Lang, Nazha Hamdani, Zsolt Bagi
Pubblicato in: Microcirculation, 2024, ISSN 1073-9688
Editore: Wiley-Blackwell
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Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.

Autori: Bullinger L, Rosenquist R, Vassilakopoulos TP, Ott G, Ogawa S, Damm F.
Pubblicato in: Leukemia, 2023, ISSN 0887-6924
Editore: Nature Publishing Group
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Small extracellular vesicles from surviving cancer cells as multiparametric monitoring tools of measurable residual disease and therapeutic efficiency.

Autori: Valcz, G., Buzás, E. I., Gatenby, R. A., Újvári, B., & Molnár, B.
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MMP-9 as Prognostic Marker for Brain Tumours: A Comparative Study on Serum-Derived Small Extracellular Vesicles.

Autori: Dobra G, Gyukity-Sebestyén E, Bukva M, Harmati M, Nagy V, Szabó Z, Pankotai T, Klekner Á, Buzás K.
Pubblicato in: Cancers, 2023, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
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Primary microglia cell cultures in translational research: Strengths and limitations.

Autori: Pesti, I., Légrádi, Á., & Farkas, E.
Pubblicato in: Journal of biotechnology, 2024, ISSN 0168-1656
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BRAF RNA is prognostic and widely expressed in lung adenocarcinoma.

Autori: Dora D, Vörös I, Varga ZV, Takacs P, Teglasi V, Moldvay J, Lohinai Z.
Pubblicato in: Translational Lung Cancer Research, 2023, ISSN 2218-6751
Editore: Society for Translational Medicine
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Heart failure pharmacotherapy and cancer: pathways and pre-clinical/clinical evidence.

Autori: Sayour, N. V., Paál, Á. M., Ameri, P., Meijers, W. C., Minotti, G., Andreadou, I., Lombardo, A., Camilli, M., Drexel, H., Grove, E. L., Dan, G. A., Ivanescu, A., Semb, A. G., Savarese, G., Dobrev, D., Crea, F., Kaski, J. C., de Boer, R. A., Ferdinandy, P., & Varga, Z. V.
Pubblicato in: European heart journal, 2024, ISSN 0195-668X
Editore: Oxford University Press
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Reviewing critical TRPM2 variants through a structure-function lens

Autori: Tóth, Á. V., & Bartók, Á.
Pubblicato in: Journal of biotechnology, 2024, ISSN 0168-1656
Editore: Elsevier BV
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IL-36α and Lipopolysaccharide Cooperatively Induce Autophagy by Triggering Pro-Autophagic Biased Signaling

Autori: Zaid I. I. Al-Luhaibi, Áron Dernovics, György Seprényi, Ferhan Ayaydin, Zsolt Boldogkői, Zoltán Veréb, Klára Megyeri
Pubblicato in: Biomedicines, Numero 9/11, 2021, Pagina/e 1541, ISSN 2227-9059
Editore: MDPI AG
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Acquired somatic variants in inherited myeloid malignancies.

Autori: Armes H, Rio-Machin A, Krizsán S, Bödör C, Kaya F, Bewicke-Copley F, Alnajar J, Walne A, Péterffy B, Tummala H, Rouault-Pierre K, Dokal I, Vulliamy T, Fitzgibbon J.
Pubblicato in: Leukemia, 2022, ISSN 0887-6924
Editore: Nature Publishing Group
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BTK and PLCG2 remain unmutated in one third of patients with CLL relapsing on ibrutinib.

Autori: Bonfiglio S, Sutton LA, Ljungström V, Capasso A, Pandzic T, Weström S, Foroughi-Asl H, Skaftason A, Gellerbring A, Lyander A, Gandini F, Gaidano G, Trentin L, Bonello L, Reda G, Bödör C, Stavroyianni N, Tam CS, Marasca R, Forconi F, Panayiotidis P, Ringshausen I, Jaksic O, Frustaci AM, Iyengar S, Coscia M, Mulligan SP, Ysebaert L, Strugov V, Pavlovsky C, Walewska R, Österborg A, Cortese D, Ra
Pubblicato in: Blood Advances, 2023, ISSN 2473-9529
Editore: Elsevier BV
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Underground metabolism as a rich reservoir for pathway engineering.

Autori: Kovács SC, Szappanos B, Tengölics R, Notebaart RA, Papp B.
Pubblicato in: Bioinformatics, 2022, ISSN 1367-4803
Editore: Oxford University Press
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The Arabidopsis Rho of Plants GTPase ROP1 Is a Potential Calcium-Dependent Protein Kinase (CDPK) Substrate

Autori: Dalma Ménesi; Éva Klement; Györgyi Ferenc; Attila Fehér
Pubblicato in: MDPI, Numero 2, 2021, ISSN 1424-3210
Editore: MDPI Plants
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Increased DNA damage of adipose tissue-derived mesenchymal stem cells under inflammatory conditions

Autori: Zoltán G. Páhi, Diána Szűcs, Vanda Miklós, Nóra Ördög, Tamás Monostori, János Varga, Lajos Kemény, Zoltán Veréb, Tibor Pankotai
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Editore: Elseiver B.V.
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Advances in phototherapy for psoriasis and atopic dermatitis

Autori: Lajos Kemény, Emese Varga, Zoltan Novak
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Maternal One-Carbon Metabolism during the Periconceptional Period and Human Foetal Brain Growth: A Systematic Review

Autori: Eleonora Rubini, Inge M. M. Baijens, Alex Horánszky, Sam Schoenmakers, Kevin D. Sinclair, Melinda Zana, András Dinnyés, Régine P. M. Steegers-Theunissen, Melek Rousian
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Editore: Multidisciplinary Digital Publishing Institute (MDPI)
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The golden ages of inflammatory skin diseases: skyrocketing developments in the therapy of psoriasis and atopic dermatitis

Autori: L. Kemény
Pubblicato in: Journal of the European Academy of Dermatology and Venereology, Numero 35/11, 2021, Pagina/e 2239-2240, ISSN 0926-9959
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Hydrogen peroxide production by epidermal dual oxidase 1 regulates nociceptive sensory signals.

Autori: Pató A, Bölcskei K, Donkó Á, Kaszás D, Boros M, Bodrogi L, Várady G, Pape VFS, Roux BT, Enyedi B, Helyes Z, Watt FM, Sirokmány G, Geiszt M.
Pubblicato in: Redox Biology, 2023, ISSN 2213-2317
Editore: Elsevier BV
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Exploring PKG signaling as a therapeutic avenue for pressure overload, ischemia, and HFpEF

Autori: S. Zhazykbayeva, H. Budde, M. Kaçmaz, Y. Zemedie, H. Osman, R. Hassoun, K. Jaquet, I. Akin, I. El-Battrawy, M. Herwig, N. Hamdani
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Extracellular vesicle release and uptake by the liver under normo- and hyperlipidemia

Autori: Krisztina Németh, Zoltán Varga, Dorina Lenzinger, Tamás Visnovitz, Anna Koncz, Nikolett Hegedűs, Ágnes Kittel, Domokos Máthé, Krisztián Szigeti, Péter Lőrincz, Clodagh O’Neill, Róisín Dwyer, Zhonglin Liu, Edit I. Buzás, Viola Tamási
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Screening and monitoring of the BTK C481S mutation in a real‐world cohort of patients with relapsed/refractory chronic lymphocytic leukaemia during ibrutinib therapy

Autori: Csaba Bödör, Lili Kotmayer, Tamás László, Ferenc Takács, Gábor Barna, Richárd Kiss, Endre Sebestyén, Tibor Nagy, Lajos László Hegyi, Gábor Mikala, Sándor Fekete, Péter Farkas, Alexandra Balogh, Tamás Masszi, Judit Demeter, Júlia Weisinger, Hussain Alizadeh, Béla Kajtár, Zoltán Kohl, Róbert Szász, Lajos Gergely, Timea Gurbity Pálfi, Adrienn Sulák, Balázs Kollár, Miklós Egy
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Editore: Blackwell Publishing Inc.
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Morphologic and molecular analysis of Richter syndrome in chronic lymphocytic leukaemia patients treated with ibrutinib or venetoclax

Autori: Ambrus Gángó, Richárd Kiss, Péter Farkas, Eid Hanna, Judit Demeter, Beáta Deák, Dóra Lévai, Lili Kotmayer, Donát Alpár, András Matolcsy, Csaba Bödör, Zoltán Mátrai, Botond Timár
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Editore: Taylor & Francis
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Novel RICTOR amplification harbouring entities: FISH validation of RICTOR amplification in tumour tissue after next-generation sequencing.

Autori: Sztankovics D, Krencz I, Moldvai D, Dankó T, Nagy Á, Nagy N, Bedics G, Rókusz A, Papp G, Tőkés AM, Pápay J, Sápi Z, Dezső K, Bödör C, Sebestyén A.
Pubblicato in: Scientific Reports, 2023, ISSN 2045-2322
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The EHA Research Roadmap: Malignant Lymphoid Diseases.

Autori: Dreyling M, André M, Gökbuget N, Tilly H, Jerkeman M, Gribben J, Ferreri A, Morel P, Stilgenbauer S, Fox C, Maria Ribera J, Zweegman S, Aurer I, Bödör C, Burkhardt B, Buske C, Dollores Caballero M, Campo E, Chapuy B, Davies A, de Leval L, Doorduijn J, Federico M, Gaulard P, Gay F, Ghia P, Grønbæk K, Goldschmidt H, Kersten MJ, Kiesewetter B, Landman-Parker J, Le Gouill S, Lenz G, Leppä S, Lo
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Editore: Wolters Kluwer Health
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Plasminogen activator inhibitor 1 is a novel faecal biomarker for monitoring disease activity and therapeutic response in inflammatory bowel diseases.

Autori: Jójárt B, Resál T, Kata D, Molnár T, Bacsur P, Szabó V, Varga Á, Szántó KJ, Pallagi P, Földesi I, Molnár T, Maléth J, Farkas K.
Pubblicato in: Journal of Corhn's Colitis, 2023, ISSN 1873-9946
Editore: Elsevier Science
DOI: 10.1093/ecco-jcc/jjad160

Alcohol in Psoriasis—From Bench to Bedside

Autori: Zita Szentkereszty-Kovács, Krisztián Gáspár, Andrea Szegedi, Lajos Kemény, Dóra Kovács, Dániel Törőcsik
Pubblicato in: International Journal of Molecular Sciences, Numero 22/9, 2021, Pagina/e 4987, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22094987

Widespread natural selection on metabolite levels in humans

Autori: Yanina Timasheva, Kaido Lepik, Orsolya Liska, Balázs Papp, Zoltán Kutalik
Pubblicato in: Genome Research, 2024, ISSN 1088-9051
Editore: Cold Spring Harbor Laboratory Press
DOI: 10.1101/gr.278756.123

Chronic Cerebral Hypoperfusion-Induced Disturbed Proteostasis of Mitochondria and MAM Is Reflected in the CSF of Rats by Proteomic Analysis.

Autori: Tukacs V, Mittli D, Hunyadi-Gulyás É, Hlatky D, Medzihradszky KF, Darula Z, Nyitrai G, Czurkó A, Juhász G, Kardos J, Kékesi KA.
Pubblicato in: Molecular Neurobiology, 2023, ISSN 0893-7648
Editore: Humana Press, Inc.
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The Combination of Single-Cell and Next-Generation Sequencing Can Reveal Mosaicism for BRCA2 Mutations and the Fine Molecular Details of Tumorigenesis

Autori: Alexandra Gráf, Márton Zsolt Enyedi, Lajos Pintér, Éva Kriston-Pál, Gábor Jaksa, Árpád Bálind, Éva Ezer, Péter Horváth, Farkas Sükösd, Ernő Kiss, Lajos Haracska
Pubblicato in: Cancers, Numero 13/10, 2021, Pagina/e 2354, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13102354

Environmental Alterations during Embryonic Development: Studying the Impact of Stressors on Pluripotent Stem Cell-Derived Cardiomyocytes

Autori: Federica Lamberto, Irene Peral-Sanchez, Suchitra Muenthaisong, Melinda Zana, Sandrine Willaime-Morawek, András Dinnyés
Pubblicato in: Genes, Numero 12/10, 2021, Pagina/e 1564, ISSN 2073-4425
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes12101564

Exploring RAD18-dependent replication of damaged DNA and discontinuities: A collection of advanced tools.

Autori: Mórocz M, Qorri E, Pekker E, Tick G, Haracska L.
Pubblicato in: Journal of Biotechnology, 2024, ISSN 0168-1656
Editore: Elsevier BV
DOI: 10.1016/j.jbiotec.2023.12.001

Genetic Investigation of Inverse Psoriasis

Autori: Anikó Göblös, Emese Varga, Katalin Farkas, Kristóf Árvai, Lajos Kemény
Pubblicato in: Life, Numero 11/7, 2021, Pagina/e 654, ISSN 2075-1729
Editore: MDPI Multidisciplinary Digital Publishing Institute
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Mitochondrial dysfunction and immune suppression in BRAF V600E‐mutated metastatic melanoma

Autori: Natália Pinto de Almeida, Ágnes Judit Jánosi, Runyu Hong, Ahmad Rajeh, Fábio Nogueira, Leticia Szadai, Beata Szeitz, Indira Pla Parada, Viktória Doma, Nicole Woldmar, Jéssica Guedes, Zsuzsanna Újfaludi, Aron Bartha, Yonghyo Kim, Charlotte Welinder, Bo Baldetorp, Lajos Vince Kemény, Zoltan Pahi, Guihong Wan, Nga Nguyen, Tibor Pankotai, Balázs Győrffy, Krzysztof Pawłowski, Peter Horvatovi
Pubblicato in: Clinical and Translational Medicine, Numero 14, 2024, ISSN 2001-1326
Editore: John Wiley & Sons Inc.
DOI: 10.1002/ctm2.1773

Deep Proteomic Analysis on Biobanked Paraffine-Archived Melanoma with Prognostic/Predictive Biomarker Read-Out.

Autori: Szadai L, Velasquez E, Szeitz B, Almeida NPd, Domont G, Betancourt LH, Gil J, Marko-Varga M, Oskolas H, Jánosi ÁJ, Boyano-Adánez MdC, Kemény L, Baldetorp B, Malm J, Horvatovich P, Szász AM, Németh IB, Marko-Varga G.
Pubblicato in: Cancers, 2021, Pagina/e 13(23):6105, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13236105

Principles of metabolome conservation in animals

Autori: Orsolya Liska, Gábor Boross, Charles Rocabert, Balázs Szappanos, Roland Tengölics, Balázs Papp
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 120, 2023, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2302147120

Sex-specific cardiovascular remodeling leads to a divergent sex-dependent development of heart failure in aged hypertensive rats

Autori: Árpád Kovács, Saltanat Zhazykbayeva, Melissa Herwig, Gábor Á. Fülöp, Tamás Csípő, Nikolett Oláh, Roua Hassoun, Heidi Budde, Hersh Osman, Mustafa Kaçmaz, Kornelia Jaquet, Dániel Priksz, Béla Juhász, Ibrahim Akin, Zoltán Papp, Wolfgang E. Schmidt, Andreas Mügge, Ibrahim El-Battrawy, Attila Tóth, Nazha Hamdani
Pubblicato in: GeroScience, 2024, ISSN 2509-2723
Editore: Springer Science and Business Media Deutschland GmbH
DOI: 10.1007/s11357-024-01160-w

Autopsy findings in cancer patients infected with SARS-CoV-2 show a milder presentation of COVID-19 compared to non-cancer patients

Autori: Éva Kocsmár, Ildikó Kocsmár, Flóra Elamin, Laura Pápai, Ákos Jakab, Tibor Várkonyi, Tibor Glasz, Gergely Rácz, Adrián Pesti, Krisztina Danics, András Kiss, Gergely Röst, Éva Belicza, Zsuzsa Schaff, Gábor Lotz
Pubblicato in: GeroScience, 2024, ISSN 2509-2723
Editore: Springer Science and Business Media Deutschland GmbH
DOI: 10.1007/s11357-024-01163-7

Shotgun Analysis of Gut Microbiota with Body Composition and Lipid Characteristics in Crohn’s Disease

Autori: Péter Bacsur, Tamás Resál, Bernadett Farkas, Boldizsár Jójárt, Zoltán Gyuris, Gábor Jaksa, Lajos Pintér, Bertalan Takács, Sára Pál, Attila Gácser, Kata Judit Szántó, Mariann Rutka, Renáta Bor, Anna Fábián, Klaudia Farkas, József Maléth, Zoltán Szepes, Tamás Molnár, Anita Bálint
Pubblicato in: Biomedicines, Numero 12, 2024, Pagina/e 2100, ISSN 2227-9059
Editore: MDPI
DOI: 10.3390/biomedicines12092100

HCN channels at the cell soma ensure the rapid electrical reactivity of fast-spiking interneurons in human neocortex.

Autori: Szegedi V, Bakos E, Furdan S, Kovács BH, Varga D, Erdélyi M, Barzó P, Szücs A, Tamás G, Lamsa K.
Pubblicato in: PlOS Biology, 2023, ISSN 1544-9173
Editore: Public Library of Science
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Comparison of mouse models of heart failure with reduced ejection fraction

Autori: Nabil V. Sayour, Tamás G. Gergely, Barnabás Váradi, Viktória É. Tóth, Bence Ágg, Tamás Kovács, Dániel Kucsera, Csenger Kovácsházi, Gábor B. Brenner, Zoltán Giricz, Péter Ferdinandy, Zoltán V. Varga
Pubblicato in: ESC Heart Failure, 2024, ISSN 2055-5822
Editore: John Wiley and Sons Inc.
DOI: 10.1002/ehf2.15031

Parathyroid cancer with MTOR gene mutation: Case report and review of the literature.

Autori: Stark J, Tőke J, Huszty G, Nagy P, Bedics G, Bödör C, Tímár J, Tóth M.
Pubblicato in: Annales d'Endocrinologie, 2023, ISSN 0003-4266
Editore: Elsevier Masson
DOI: 10.1016/j.ando.2023.06.003

Tamás SX, Roux BT, Vámosi B, Dehne FG, Török A, Fazekas L, Enyedi B.

Autori: A genetically encoded sensor for visualizing leukotriene B4 gradients in vivo.
Pubblicato in: Nature Communications, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-023-40326-6

Fibroblast-Derived Extracellular Vesicles Induce Colorectal Cancer Progression by Transmitting Amphiregulin

Autori: Ádám Oszvald, Zsuzsanna Szvicsek, Márton Pápai, Andrea Kelemen, Zoltán Varga, Tamás Tölgyes, Kristóf Dede, Attila Bursics, Edit I. Buzás, Zoltán Wiener
Pubblicato in: Frontiers in Cell and Developmental Biology, Numero 8, 2020, ISSN 2296-634X
Editore: Frontiers Media S.A.
DOI: 10.3389/fcell.2020.00558

Understanding Differences in Sex-Based Outcomes with Dual Antiplatelet Therapy After Percutaneous Coronary Intervention

Autori: Ibrahim Akin, Nazha Hamdani, Ibrahim El-Battrawy
Pubblicato in: Drugs, Numero 84, 2024, Pagina/e 703-705, ISSN 0012-6667
Editore: Adis International Ltd.
DOI: 10.1007/s40265-024-02041-4

Biofilm formation initiating rotifer-specific biopolymer and its predicted components

Autori: Zsolt Datki, Zsuzsanna Darula, Viktor Vedelek, Eva Hunyadi-Gulyas, Brian J. Dingmann, Balazs Vedelek, Janos Kalman, Peter Urban, Attila Gyenesei, Zita Galik-Olah, Bence Galik, Rita Sinka
Pubblicato in: International Journal of Biological Macromolecules, Numero 253, 2023, Pagina/e 127157, ISSN 0141-8130
Editore: Elsevier BV
DOI: 10.1016/j.ijbiomac.2023.127157

PACAP-38 and PAC1 Receptor Alterations in Plasma and Cardiac Tissue Samples of Heart Failure Patients.

Autori: Szabó D, Sárszegi Z, Polgár B, Sághy É, Reglődi D, Tóth T, Onódi Z, Leszek P, Varga ZV, Helyes Z, Kemény Á, Ferdinandy P, Tamás A.
Pubblicato in: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23073715

CD3+/CD56+ NKT-like Cells Show Imbalanced Control Immediately after Exercise in Delayed-Onset Muscle Soreness.

Autori: Sonkodi B, Pállinger É, Radovits T, Csulak E, Shenker-Horváth K, Kopper B, Buzás EI, Sydó N, Merkely B.
Pubblicato in: International Journal of Molecular Sciences, Numero 14220067, 2022, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms231911117

Genomic Landscape of Normal and Breast Cancer Tissues in a Hungarian Pilot Cohort.

Autori: Pipek O, Alpár D, Rusz O, Bödör C, Udvarnoki Z, Medgyes-Horváth A, Csabai I, Szállási Z, Madaras L, Kahán Z, Cserni G, Kővári B, Kulka J, Tőkés AM.
Pubblicato in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24108553

Initial and ongoing tobacco smoking elicits vascular damage and distinct inflammatory response linked to neurodegeneration.

Autori: Garza AP, Morton L, Pállinger É, Buzás EI, Schreiber S, Schott BH, Dunay IR.
Pubblicato in: Brain, Behaviour and Immunity, 2023, ISSN 0889-1591
Editore: Academic Press
DOI: 10.1016/j.bbih.2023.100597

Genomic surveillance as a scalable framework for precision phage therapy against antibiotic-resistant pathogens

Autori: Mihály Koncz, Tamás Stirling, Hiba Hadj Mehdi, Orsolya Méhi, Bálint Eszenyi, András Asbóth, Gábor Apjok, Ákos Tóth, László Orosz, Bálint Márk Vásárhelyi, Eszter Ari, Lejla Daruka, Tamás Ferenc Polgár, György Schneider, Sif Aldin Zalokh, Mónika Számel, Gergely Fekete, Balázs Bohár, Karolina Nagy Varga, Ádám Visnyovszki, Edit Székely, Monica-Sorina Licker, Oana Izmendi, Carm
Pubblicato in: Cell, 2024, ISSN 0092-8674
Editore: Cell Press
DOI: 10.1016/j.cell.2024.09.009

The ROP2 GTPase Participates in Nitric Oxide (NO)-Induced Root Shortening in Arabidopsis

Autori: Erzsébet Kenesi, Zsuzsanna Kolbert, Nikolett Kaszler, Éva Klement, Dalma Ménesi, Árpád Molnár, Ildikó Valkai, Gábor Feigl, Gábor Rigó, Ágnes Cséplő, Christian Lindermayr, Attila Fehér
Pubblicato in: Plants, Numero 12, 2023, Pagina/e 750, ISSN 2223-7747
Editore: MDPI
DOI: 10.3390/plants12040750

Fountain of youth—Targeting autophagy in aging

Autori: Lea Danics, Anna Anoir Abbas, Balázs Kis, Karolina Pircs
Pubblicato in: Frontiers in Aging Neuroscience, Numero 15, 2023, ISSN 1663-4365
Editore: Frontiers Research Foundation
DOI: 10.3389/fnagi.2023.1125739

Lipids and Trehalose Actively Cooperate in Heat Stress Management of Schizosaccharomyces pombe.

Autori: Péter M, Gudmann P, Kóta Z, Török Z, Vígh L, Glatz A, Balogh G.
Pubblicato in: Journal of Molecular Sciences, 2021, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms222413272

Negative trade-off between neoantigen repertoire breadth and the specificity of HLA-I molecules shapes antitumor immunity

Autori: Máté Manczinger, Balázs Koncz, Gergő Mihály Balogh, Benjamin Tamás Papp, Leó Asztalos, Lajos Kemény, Balázs Papp, Csaba Pál
Pubblicato in: Nature Cancer, 2021, ISSN 2662-1347
Editore: Nature Research (subsidiary of Springer Nature)
DOI: 10.1038/s43018-021-00226-4

Complex treatment of residual metastatic germ cell cancer: A single center experience

Autori: Fruzsina Eszter Fazekas, Zsuzsanna Ujfaludi, Krisztina Biró, Zoltán Gábor Páhi, István Buzogány, Farkas Sükösd, Tibor Pankotai, Tamás Beöthe
Pubblicato in: Journal of Biotechnology, Numero 389, 2024, Pagina/e 61-67, ISSN 0168-1656
Editore: Elsevier BV
DOI: 10.1016/j.jbiotec.2024.04.018

Development and Functional Characterization of a Versatile Radio-/Immunotheranostic Tool for Prostate Cancer Management.

Autori: Arndt C, Bergmann R, Striese F, Merkel K, Máthé D, Loureiro LR, Mitwasi N, Kegler A, Fasslrinner F, González Soto KE, Neuber C, Berndt N, Kovács N, Szöllősi D, Hegedűs N, Tóth G, Emmermann J-P, Harikumar KB, Kovacs T, Bachmann M, Feldmann A.
Pubblicato in: Cancers, 2022, ISSN 2072-6694
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14081996

CDK-independent role of D-type cyclins in regulating DNA mismatch repair.

Autori: Rona, G., Miwatani-Minter, B., Zhang, Q., Goldberg, H. V., Kerzhnerman, M. A., Howard, J. B., Simoneschi, D., Lane, E., Hobbs, J. W., Sassani, E., Wang, A. A., Keegan, S., Laverty, D. J., Piett, C. G., Pongor, L. S., Xu, M. L., Andrade, J., Thomas, A., Sicinski, P., Askenazi, M., … Pagano, M.
Pubblicato in: Molecular cell, 2024, ISSN 1097-2765
Editore: Cell Press
DOI: 10.1016/j.molcel.2024.02.010

Parallel testing of liquid biopsy (ctDNA) and tissue biopsy samples reveals a higher frequency of EZH2 mutations in follicular lymphoma.

Autori: Timár B, Csomor J, Tóth E, Schneider T, Mikala G, Matolcsy A, Alpár D, Masszi A, Bödör C.
Pubblicato in: Journal of Internal Medicine, 2023, ISSN 0954-6820
Editore: Blackwell Publishing Inc.
DOI: 10.1111/joim.13674

Intraperitoneal Glucose Transport to Micrometastasis: A Multimodal In Vivo Imaging Investigation in a Mouse Lymphoma Model

Autori: Zsombor Ritter, Katalin Zámbó, Xinkai Jia, Dávid Szöllősi, Dániel Dezső, Hussain Alizadeh, Ildikó Horváth, Nikolett Hegedűs, David Tuch, Kunal Vyas, Péter Balogh, Domokos Máthé, Erzsébet Schmidt
Pubblicato in: International Journal of Molecular Sciences, Numero 22/9, 2021, Pagina/e 4431, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22094431

Molecular fingerprints of cardiovascular toxicities of immune checkpoint inhibitors

Autori: Tamás G. Gergely, Zsófia D. Drobni, Nabil V. Sayour, Péter Ferdinandy, Zoltán V. Varga
Pubblicato in: Basic Research in Cardiology, 2024, ISSN 1435-1803
Editore: D. Steinkopff-Verlag
DOI: 10.1007/s00395-024-01068-8

β-Endorphin mediates radiation therapy fatigue.

Autori: Hermann AL, Fell GL, Kemény LV, Fung CY, Held KD, Biggs PJ, Rivera PD, Bilbo SD, Igras V, Willers H, Kung J, Gheorghiu L, Hideghéty K, Mao J, Woolf CJ, Fisher DE.
Pubblicato in: Science advances, 2022, ISSN 2375-2548
Editore: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abn6025

Antimicrobial resistance: a concise update

Autori: Charlotte S Ho, Carlos T H Wong, Thet Tun Aung, Rajamani Lakshminarayanan, Jodhbir S Mehta, Saaeha Rauz, Alan McNally, Balint Kintses, Sharon J Peacock, Cesar de la Fuente-Nunez, Robert E W Hancock, Darren S J Ting
Pubblicato in: The Lancet Microbe, 2024, Pagina/e 100947, ISSN 2666-5247
Editore: Elsevier Ltd.
DOI: 10.1016/j.lanmic.2024.07.010

Anticancer Potential of L-Histidine-Capped Silver Nanoparticles against Human Cervical Cancer Cells (SiHA).

Autori: Mohammed Asik R, Manikkaraja C, Tamil Surya K, Suganthy N, Priya Aarthy A, Mathe D, Sivakumar M, Archunan G, Padmanabhan P, Gulyas B.
Pubblicato in: Nanomaterials, 2021, ISSN 2079-4991
Editore: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/nano11113154

Supraoptimal Iron Nutrition of Brassica napus Plants Suppresses the Iron Uptake of Chloroplasts by Down-Regulating Chloroplast Ferric Chelate Reductase

Autori: Máté Sági-Kazár, Helga Zelenyánszki, Brigitta Müller, Barnabás Cseh, Balázs Gyuris, Sophie Z. Farkas, Ferenc Fodor, Brigitta Tóth, Béla Kovács, Anna Koncz, Tamás Visnovitz, Edit I. Buzás, Barbara Bánkúti, Ferenc Bánáti, Kálmán Szenthe and Ádám Solti
Pubblicato in: Frontiers in Plant Science, 2021, Pagina/e 12/748, ISSN 1664-462X
Editore: Frontiers Media S. A.
DOI: 10.3389/fpls.2021.658987

Membrane Domain Localization and Interaction of the Prion-Family Proteins, Prion and Shadoo with Calnexin.

Autori: Dondapati DT, Cingaram PR, Ayaydin F, Nyeste A, Kanyó A, Welker E, Fodor E.
Pubblicato in: MDPI Membranes, 2021, ISSN 2077-0375
Editore: Molecular Diversity Preservation International
DOI: 10.3390/membranes11120978

A Photo-clickable ATP-Mimetic Reveals Nucleotide Interactors in the Membrane Proteome

Autori: Mark Jelcic, Ke Wang, King Lam Hui, Xiao-Chuan Cai, Balázs Enyedi, Minkui Luo, Philipp Niethammer
Pubblicato in: Cell Chemical Biology, Numero 27/8, 2020, Pagina/e 1073-1083.e12, ISSN 2451-9456
Editore: Elsevier Inc.
DOI: 10.1016/j.chembiol.2020.05.010

The effect of antifungal resistance development on the virulence of Candida species.

Autori: Bohner F, Papp C, Gácser A.
Pubblicato in: FEMS Yeast Research, 2022, ISSN 1567-1356
Editore: Blackwell
DOI: 10.1093/femsyr/foac019

Functionalized Mesoporous Silica Nanoparticles for Drug-Delivery to Multidrug-Resistant Cancer Cells.

Autori: Igaz N, Bélteky P, Kovács D, Papp C, Rónavári A, Szabó D, Gácser A, Kónya Z, Kiricsi M.
Pubblicato in: International Journal of Nanomedicine, 2022, ISSN 1176-9114
Editore: Dove Medical Press Ltd
DOI: 10.2147/ijn.s363952

Reorganization of the actin cytoskeleton during the formation of neutrophil extracellular traps (NETs).

Autori: Mannherz, H. G., Budde, H., Jarkas, M., Hassoun, R., Malek-Chudzik, N., Mazur, A. J., Skuljec, J., Pul, R., Napirei, M., & Hamdani, N.
Pubblicato in: European journal of cell biology, 2024, ISSN 0171-9335
Editore: Elsevier BV
DOI: 10.1016/j.ejcb.2024.151407

Thrombocytosis and Effects of IL-6 Knock-Out in a Colitis-Associated Cancer Model

Autori: Valeria Josa, Szilamer Ferenczi, Rita Szalai, Eniko Fuder, Daniel Kuti, Krisztina Horvath, Nikolett Hegedus, Tibor Kovacs, Gergo Bagamery, Balazs Juhasz, Zsuzsanna Winkler, Daniel S. Veres, Zsombor Zrubka, Domokos Mathe, Zsolt Baranyai
Pubblicato in: International Journal of Molecular Sciences, Numero 21/17, 2020, Pagina/e 6218, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21176218

Novel, clinically relevant genomic patterns identified by comprehensive genomic profiling in ATRX-deficient IDH-wildtype adult high-grade gliomas.

Autori: Bedics G, Szőke P, Bátai B, Nagy T, Papp G, Kránitz N, Rajnai H, Reiniger L, Bödör C, Scheich B.
Pubblicato in: Scienntific Reports, 2023, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-023-45786-w

CD44 Expression Intensity Marks Colorectal Cancer Cell Subpopulations with Different Extracellular Vesicle Release Capacity.

Autori: Kelemen A, Carmi I, Seress I, Lőrincz P, Tölgyes T, Dede K, Bursics A, Buzás EI, Wiener Z.
Pubblicato in: International journal of molecular sciences, 2022, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23042180

Balanced Intense Exercise Training Induces Atrial Oxidative Stress Counterbalanced by the Antioxidant System and Atrial Hypertrophy That Is Not Associated with Pathological Remodeling or Arrhythmogenicity

Autori: Attila Oláh, Bálint András Barta, Alex Ali Sayour, Mihály Ruppert, Eszter Virág-Tulassay, Julianna Novák, Zoltán V. Varga, Péter Ferdinandy, Béla Merkely, Tamás Radovits
Pubblicato in: Antioxidants, Numero 10/3, 2021, Pagina/e 452, ISSN 2076-3921
Editore: MDPI Multidisciplinary Digital Publishing Institute
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Self-mediated positive selection of T cells sets an obstacle to the recognition of nonself

Autori: Balázs Koncz, Gergő M. Balogh, Benjamin T. Papp, Leó Asztalos, Lajos Kemény, Máté Manczinger
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Editore: National Academy of Sciences
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Monitoring correlates of SARS-CoV-2 infection in cell culture using a two-photon-active calcium-sensitive dye

Autori: Domokos Máthé, Gergely Szalay, Levente Cseri, Zoltán Kis, Bernadett Pályi, Gábor Földes, Noémi Kovács, Anna Fülöp, Áron Szepesi, Polett Hajdrik, Attila Csomos, Ákos Zsembery, Kristóf Kádár, Gergely Katona, Zoltán Mucsi, Balázs József Rózsa, Ervin Kovács
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Reinstating olfactory bulb-derived limbic gamma oscillations alleviates depression-like behavioral deficits in rodents.

Autori: Li Q, Takeuchi Y, Wang J, Gellért L, Barcsai L, Pedraza LK, Nagy AJ, Kozák G, Nakai S, Kato S, Kobayashi K, Ohsawa M, Horváth G, Kékesi G, Lőrincz ML, Devinsky O, Buzsáki G, Berényi A.
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Impaired regulation of PMCA activity by defective CFTR expression promotes epithelial cell damage in alcoholic pancreatitis and hepatitis

Autori: Madácsy T, Varga Á, Papp N, Tél B, Pallagi P, Szabó V, Kiss A, Fanczal J, Rakonczay Z Jr, Tiszlavicz L, Rázga Z, Hohwieler M, Kleger A, Gray M, Hegyi P, Maléth J
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Lactobacillus acidophilus, L. plantarum, L. rhamnosus, and L. reuteri Cell-Free Supernatants Inhibit Candida parapsilosis Pathogenic Potential upon Infection of Vaginal Epithelial Cells Monolayer and in a Transwell Coculture System In Vitro.

Autori: Spaggiari L, Sala A, Ardizzoni A, De Seta F, Singh DK, Gacser A, Blasi E, Pericolini E.
Pubblicato in: Microbiology spectrum, 2022, ISSN 2165-0497
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A single early introduction governed viral diversity in the second wave of SARS-CoV-2 epidemic in Hungary.

Autori: Ari E, Vásárhelyi BM, Kemenesi G, Tóth GE, Zana B, Somogyi B, Lanszki Z, Röst G, Jakab F, Papp B, Kintses B.
Pubblicato in: Virus Evolution, Numero 20571577, 2022, ISSN 2057-1577
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Methods for the identification and characterization of extracellular vesicles in cardiovascular studies - from exosomes to microvesicles.

Autori: Davidson SM, Boulanger CM, Aikawa E, Badimon L, Barile L, Binder CJ, Brisson A, Buzas E, Emanueli C, Jansen F, Katsur M, Lacroix R, Lim SK, Mackman N, Mayr M, Menasché P, Nieuwland R, Sahoo S, Takov K, Thum T, Vader P, Wauben MHM, Witwer K, Sluijter JPG.
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Editore: Oxford University Press
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Chronic Exposure to the Food Additive tBHQ Modulates Expression of Genes Related to SARS-CoV-2 and Influenza Viruses.

Autori: Németh K, Petschner P, Pálóczi K, Fekete N, Pállinger É, Buzás EI, Tamási V.
Pubblicato in: Life, 2022, ISSN 2075-1729
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
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Functional characterization of the transient receptor potential melastatin 2 (TRPM2) cation channel from Nematostella vectensis reconstituted into lipid bilayer.

Autori: Szollosi A, Almássy J.
Pubblicato in: Scientific Reports, 2023, ISSN 2045-2322
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The metabolic domestication syndrome of budding yeast

Autori: Roland Tengölics, Balázs Szappanos, Michael Mülleder, Dorottya Kalapis, Gábor Grézal, Csilla Sajben, Federica Agostini, João Benhur Mokochinski, Balázs Bálint, László G. Nagy, Markus Ralser, Balázs Papp
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Editore: National Academy of Sciences
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Folate-Targeted Monodisperse PEG-Based Conjugates Made by Chemo-Enzymatic Methods for Cancer Diagnosis and Treatment

Autori: Krisztina S. Nagy, Krisztina Toth, Eva Pallinger, Angela Takacs, Laszlo Kohidai, Angela Jedlovszky-Hajdu, Domokos Mathe, Noemi Kovacs, Daniel S. Veres, Krisztian Szigeti, Kristof Molnar, Eniko Krisch, Judit E. Puskas
Pubblicato in: International Journal of Molecular Sciences, Numero 22/19, 2021, Pagina/e 10347, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
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Higher-order thalamic nuclei facilitate the generalization and maintenance of spike-and-wave discharges of absence seizures.

Autori: Atherton Z, Nagy O, Barcsai L, Sere P, Zsigri N, Földi T, Gellért L, Berényi A, Crunelli V, Lőrincz ML.
Pubblicato in: Neurobiology of Disease, 2023, ISSN 0969-9961
Editore: Academic Press
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Signaling through Syk or CARD9 Mediates Species-Specific Anti- Candida Protection in Bone Marrow Chimeric Mice

Autori: Erik Zajta, Katalin Csonka, Adél Tóth, Laszló Tiszlavicz, Tamás Németh, Anita Orosz, Ádám Novák, Máté Csikós, Csaba Vágvölgyi, Attila Mócsai, Attila Gácser
Pubblicato in: mBio, Numero 12/4, 2021, ISSN 2150-7511
Editore: American Society for Microbiology
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Integrated evolutionary analysis reveals antimicrobial peptides with limited resistance

Autori: Réka Spohn, Lejla Daruka, Viktória Lázár, Ana Martins, Fanni Vidovics, Gábor Grézal, Orsolya Méhi, Bálint Kintses, Mónika Számel, Pramod K. Jangir, Bálint Csörgő, Ádám Györkei, Zoltán Bódi, Anikó Faragó, László Bodai, Imre Földesi, Diána Kata, Gergely Maróti, Bernadett Pap, Roland Wirth, Balázs Papp, Csaba Pál
Pubblicato in: Nature Communications, Numero 10/1, 2019, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-019-12364-6

Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action

Autori: Bálint Kintses, Pramod K. Jangir, Gergely Fekete, Mónika Számel, Orsolya Méhi, Réka Spohn, Lejla Daruka, Ana Martins, Ali Hosseinnia, Alla Gagarinova, Sunyoung Kim, Sadhna Phanse, Bálint Csörgő, Ádám Györkei, Eszter Ari, Viktória Lázár, István Nagy, Mohan Babu, Csaba Pál, Balázs Papp
Pubblicato in: Nature Communications, Numero 10/1, 2019, ISSN 2041-1723
Editore: Nature Publishing Group
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Unmatched level of molecular convergence among deeply divergent complex multicellular fungi

Autori: Zsolt Merényi, Arun N Prasanna, Zheng Wang, Károly Kovács, Botond Hegedüs, Balázs Bálint, Balázs Papp, Jeffrey P Townsend, László G Nagy
Pubblicato in: Molecular Biology and Evolution, 2020, ISSN 0737-4038
Editore: Oxford University Press
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Rapid decline of bacterial drug-resistance in an antibiotic-free environment through phenotypic reversion

Autori: Anett Dunai, Réka Spohn, Zoltán Farkas, Viktória Lázár, Ádám Györkei, Gábor Apjok, Gábor Boross, Balázs Szappanos, Gábor Grézal, Anikó Faragó, László Bodai, Balázs Papp, Csaba Pál
Pubblicato in: eLife, 2019, ISSN 2050-084X
Editore: eLife Sciences Publications
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Activity-based protein profiling of the human failing ischemic heart reveals alterations in hydrolase activities involving the endocannabinoid system

Autori: Annelot C.M. van Esbroeck, Zoltan V. Varga, Xinyu Di, Eva J. van Rooden, Viktória E. Tóth, Zsófia Onódi, Mariusz Kuśmierczyk, Przemyslaw Leszek, Péter Ferdinandy, Thomas Hankemeier, Mario van der Stelt, Pál Pacher
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Editore: Academic Press
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Extracellular vesicles transmit epithelial growth factor activity in the intestinal stem cell niche

Autori: Ádám Oszvald, Zsuzsanna Szvicsek, Gyöngyvér Orsolya Sándor, Andrea Kelemen, András Áron Soós, Krisztina Pálóczi, Attila Bursics, Kristóf Dede, Tamás Tölgyes, Edit I. Buzás, Anikó Zeöld, Zoltán Wiener
Pubblicato in: STEM CELLS, 2019, ISSN 1066-5099
Editore: AlphaMed Press Inc
DOI: 10.1002/stem.3113

Unravelling the Role of Trophoblastic-Derived Extracellular Vesicles in Regulatory T Cell Differentiation

Autori: Árpád Ferenc Kovács, Nóra Fekete, Lilla Turiák, András Ács, László Kőhidai, Edit I. Buzás, Éva Pállinger
Pubblicato in: International Journal of Molecular Sciences, Numero 20/14, 2019, Pagina/e 3457, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20143457

Cartilage Oligomeric Matrix Protein Negatively Influences Keratinocyte Proliferation Via α5β1-Integrin: Potential Relevance of Altered Cartilage Oligomeric Matrix Protein Expression in Psoriasis

Autori: Renáta Bozó, Edit Szél, Judit Danis, Barbara Gubán, Zsuzsanna Bata-Csörgő, Kornélia Szabó, Lajos Kemény, Gergely Groma
Pubblicato in: Journal of Investigative Dermatology, 2020, ISSN 0022-202X
Editore: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2019.12.037

Comprehensive Proteomic Analysis Reveals Intermediate Stage of Non-Lesional Psoriatic Skin and Points out the Importance of Proteins Outside this Trend

Autori: Edit Szél, Renáta Bozó, Éva Hunyadi-Gulyás, Máté Manczinger, Kornélia Szabó, Lajos Kemény, Zsuzsanna Bata-Csörgő, Gergely Groma
Pubblicato in: Scientific Reports, Numero 9/1, 2019, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-019-47774-5

Targeting the gut‐skin axis—Probiotics as new tools for skin disorder management?

Autori: Magdolna Szántó, Anikó Dózsa, Dóra Antal, Kornélia Szabó, Lajos Kemény, Péter Bai
Pubblicato in: Experimental Dermatology, Numero 28/11, 2019, Pagina/e 1210-1218, ISSN 0906-6705
Editore: Blackwell Publishing Inc.
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Exploring the fitness benefits of genome reduction in Escherichia coli by a selection-driven approach

Autori: Viktor Vernyik, Ildikó Karcagi, Edit Tímár, István Nagy, Ádám Györkei, Balázs Papp, Zsuzsanna Györfy, György Pósfai
Pubblicato in: Scientific Reports, Numero 10/1, 2020, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-020-64074-5

Multilevel structure–activity profiling reveals multiple green tea compound families that each modulate ubiquitin-activating enzyme and ubiquitination by a distinct mechanism

Autori: Gabriel Fenteany, Paras Gaur, Lili Hegedűs, Kata Dudás, Ernő Kiss, Edit Wéber, László Hackler, Tamás Martinek, László G. Puskás, Lajos Haracska
Pubblicato in: Scientific Reports, Numero 9/1, 2019, ISSN 2045-2322
Editore: Nature Publishing Group
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Robust high-throughput assays to assess discrete steps in ubiquitination and related cascades

Autori: Gabriel Fenteany, Paras Gaur, Gaurav Sharma, Lajos Pintér, Ernő Kiss, Lajos Haracska
Pubblicato in: BMC Molecular and Cell Biology, Numero 21/1, 2020, ISSN 2661-8850
Editore: Springer Nature
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The Role of P2X7 Receptor in Alzheimer’s Disease

Autori: Linda Francistiová, Carolina Bianchi, Caterina Di Lauro, Álvaro Sebastián-Serrano, Laura de Diego-García, Julianna Kobolák, András Dinnyés, Miguel Díaz-Hernández
Pubblicato in: Frontiers in Molecular Neuroscience, Numero 13, 2020, ISSN 1662-5099
Editore: Frontiers Research Foundation
DOI: 10.3389/fnmol.2020.00094

Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System

Autori: Kinga Tóth, Dorottya Ádám, Tamás Bíró, Attila Oláh
Pubblicato in: Molecules, Numero 24/5, 2019, Pagina/e 918, ISSN 1420-3049
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules24050918

Nicotinic acid suppresses sebaceous lipogenesis of human sebocytes via activating hydroxycarboxylic acid receptor 2 (HCA 2 )

Autori: Arnold Markovics, Kinga Fanni Tóth, Katalin Eszter Sós, József Magi, Adrienn Gyöngyösi, Zoltán Benyó, Christos C. Zouboulis, Tamás Bíró, Attila Oláh
Pubblicato in: Journal of Cellular and Molecular Medicine, Numero 23/9, 2019, Pagina/e 6203-6214, ISSN 1582-1838
Editore: Wiley-Blackwell
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Advances in the optimisation of therapeutic drug monitoring using serum, tissue and faecal anti-tumour necrosis factor concentration in patients with inflammatory bowel disease treated with TNF-α antagonists

Autori: Kata Judit Szántó, Tamara Madácsy, Diána Kata, Tamás Ferenci, Mariann Rutka, Anita Bálint, Renáta Bor, Anna Fábián, Ágnes Milassin, Boldizsár Jójárt, Zoltán Szepes, Ferenc Nagy, Tamás Molnár, Imre Földesi, József Maléth & Klaudia Farkas
Pubblicato in: Expert Opinion on Biological Therapy, 2021, ISSN 1744-7682
Editore: Taylor & Francis Ltd.
DOI: 10.1080/14712598.2021.1890712

Myelofibrosis progression grading based on type-I and type-III collagen and fibrillin-1 expression boosted by whole slide image analysis.

Autori: Szekely T, Wichmann B, Maros ME, Csizmadia A, Bodor C, Timar B, Krenacs T.
Pubblicato in: Histopathology, Numero 03090167, 2022, ISSN 0309-0167
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Optimization of the Heterologous Expression of the Cannabinoid Type-1 (CB1) Receptor

Autori: Viktória B. Horváth, Eszter Soltész-Katona, Éva Wisniewski, Anikó Rajki, Eszter Halász, Balázs Enyedi, László Hunyady, András Dávid Tóth, Gergő Szanda
Pubblicato in: Frontiers in Endocrinology, Numero 12, 2021, ISSN 1664-2392
Editore: Frontiers Media S.A.
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Acquired Triazole Resistance Alters Pathogenicity-Associated Features in Candida auris in an Isolate-Dependent Manner.

Autori: Bohner F, Papp C, Takacs T, Varga M, Szekeres A, Nosanchuk JD, Vágvölgyi C, Tóth R, Gacser A.
Pubblicato in: Journal of Fungi, 2023, ISSN 2309-608X
Editore: MDPI
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Terápiás kihívások nehezen kezelhető, penetráló Crohn-betegségben – multidiszciplináris megoldás

Autori: Bernadett Farkas, Péter Bacsur, Emese Ivány, Anita Bálint, Mariann Rutka, Klaudia Farkas, Tamás Molnár
Pubblicato in: Orvosi Hetilap, Numero 165, 2024, Pagina/e 1252-1257, ISSN 0030-6002
Editore: Akademiai Kiado
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Phenol-Soluble Modulin α3 Stimulates Autophagy in HaCaT Keratinocytes.

Autori: Dernovics Á, Seprényi G, Rázga Z, Ayaydin F, Veréb Z, Megyeri K.
Pubblicato in: Biomedicines, 2023, ISSN 2227-9059
Editore: MDPI
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Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells

Autori: Markus Breunig, Jessica Merkle, Martin Wagner, Michael K. Melzer, Thomas F.E. Barth, Thomas Engleitner, Johannes Krumm, Sandra Wiedenmann, Christian M. Cohrs, Lukas Perkhofer, Gaurav Jain, Jana Krüger, Patrick C. Hermann, Maximilian Schmid, Tamara Madácsy, Árpád Varga, Joscha Griger, Ninel Azoitei, Martin Müller, Oliver Wessely, Pamela G. Robey, Sandra Heller, Zahra Dantes, Maximilian Reicher
Pubblicato in: Cell Stem Cell, 2021, ISSN 1934-5909
Editore: Cell Press
DOI: 10.1016/j.stem.2021.03.005

Author Correction: Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling

Autori: Eric Schoger, Federico Bleckwedel, Giulia Germena, Cheila Rocha, Petra Tucholla, Izzatullo Sobitov, Wiebke Möbius, Maren Sitte, Christof Lenz, Mostafa Samak, Rabea Hinkel, Zoltán V. Varga, Zoltán Giricz, Gabriela Salinas, Julia C. Gross, Laura C. Zelarayán
Pubblicato in: Communications Biology, Numero 7, 2024, ISSN 2399-3642
Editore: Springer Nature
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Histone and Histone Acetylation-Related Alterations of Gene Expression in Uninvolved Psoriatic Skin and Their Effects on Cell Proliferation, Differentiation, and Immune Responses.

Autori: Romhányi D, Szabó K, Kemény L, Groma G.
Pubblicato in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms241914551

Development of a Large-Scale Pathogen Screening Test for the Biosafety Evaluation of Canine Mesenchymal Stem Cells.

Autori: Pekker E, Priskin K, Szabó-Kriston É, Csányi B, Buzás-Bereczki O, Adorján L, Szukacsov V, Pintér L, Rusvai M, Cooper P, Kiss-Tóth E, Haracska L.
Pubblicato in: Biological Procedures Online, 2023, ISSN 1480-9222
Editore: BioMed Central
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No beneficial use of the wearable cardioverter defibrillator among patients suffering from inherited and congenital heart disease: data from a European multicenter registry

Autori: Katharina Koepsel, Tobias C. Dreher, Christian Blockhaus, Michael Gotzmann, Norbert Klein, Thomas Kuntz, Dong-In Shin, Hendrik Lapp, Fabian Schiedat, Mohammad Abumayyaleh, Thomas Beiert, Christian Weth, Boldizsar Kovacs, Stephanie Rosenkaimer, Jacqueline Kowitz, Ardan Muammer Saguner, Julia W. Erath, Firat Duru, Andreas Mügge, Ibrahim Akin, Assem Aweimer, Nazha Hamdani, Ibrahim El-Battrawy
Pubblicato in: Frontiers in Cardiovascular Medicine, Numero 11, 2024, ISSN 2297-055X
Editore: Frontiers Media SA
DOI: 10.3389/fcvm.2024.1384736

Cardiac miRNA Expression and their mRNA Targets in a Rat Model of Prediabetes

Autori: Éva Sághy, Imre Vörös, Bence Ágg, Bernadett Kiss, Gábor Koncsos, Zoltán V. Varga, Anikó Görbe, Zoltán Giricz, Rainer Schulz, Péter Ferdinandy
Pubblicato in: International Journal of Molecular Sciences, Numero 21/6, 2020, Pagina/e 2128, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
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Nodular fasciitis: a comprehensive, time-correlated investigation of 17 cases

Autori: Zoltán Sápi, Zoltán Lippai, Gergő Papp, Lajos Hegyi, Johanna Sápi, Katalin Dezső, Károly Szuhai
Pubblicato in: Modern Pathology, 2021, ISSN 0893-3952
Editore: Nature Publishing Group
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The Wisdom in Teeth: Neuronal Differentiation of Dental Pulp Cells.

Autori: Sramkó B, Földes A, Kádár K, Varga G, Zsembery Á, Pircs K.
Pubblicato in: Cellular Reprogramming, 2023, ISSN 2152-4971
Editore: Mary Ann Liebert Inc.
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A complete nicotinate degradation pathway in the microbial eukaryote Aspergillus nidulans.

Autori: Bokor E, Ámon J, Varga M, Szekeres A, Hegedűs Z, Jakusch T, Szakonyi Z, Flipphi M, Vágvölgyi C, Gácser A, Scazzocchio C, Hamari Z.
Pubblicato in: Communications Biology, 2022, ISSN 2399-3642
Editore: Springer Nature
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Periodontitis: a newly identified comorbidity in psoriasis and psoriatic arthritis

Autori: Szandra Dalmády, Lajos Kemény, Márk Antal, Rolland Gyulai
Pubblicato in: Expert Review of Clinical Immunology, Numero 16/1, 2020, Pagina/e 101-108, ISSN 1744-666X
Editore: Future Drugs Ltd.
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An Implantable Magneto-Responsive Poly(aspartamide) Based Electrospun Scaffold for Hyperthermia Treatment.

Autori: Veres T, Voniatis C, Molnár K, Nesztor D, Fehér D, Ferencz A, Gresits I, Thuróczy G, Márkus BG, Simon F, Nemes NM, García-Hernández M, Reiniger L, Horváth I, Máthé D, Szigeti K, Tombácz E, Jedlovszky-Hajdu A.
Pubblicato in: Nanomaterials, 2022, ISSN 2079-4991
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nano12091476

Reduced MC4R signaling alters nociceptive thresholds associated with red hair

Autori: Kathleen C. Robinson, Lajos V. Kemény, Gillian L. Fell, Andrea L. Hermann, Jennifer Allouche, Weihua Ding, Ajay Yekkirala, Jennifer J. Hsiao, Mack Y. Su, Nicholas Theodosakis, Gabor Kozak, Yuichi Takeuchi, Shiqian Shen, Antal Berenyi, Jianren Mao, Clifford J. Woolf, David E. Fisher
Pubblicato in: Science Advances, Numero 7/14, 2021, Pagina/e eabd1310, ISSN 2375-2548
Editore: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abd1310

Nanoinjection of extracellular vesicles to single live cells by robotic fluidic force microscopy.

Autori: Kovács KD, Visnovitz T, Gerecsei T, Peter B, Kurunczi S, Koncz A, Németh K, Lenzinger D, Vukman KV, Balogh A, Rajmon I, Lőrincz P, Székács I, Buzás EI, Horvath R.
Pubblicato in: Journal of Extracellular Vesicles, 2023, ISSN 2001-3078
Editore: John Wiley & Sons Inc.
DOI: 10.1002/jev2.12388

Virulence Factors and in-Host Selection on Phenotypes in Infectious Probiotic Yeast Isolates (Saccharomyces ‘boulardii’)

Autori: Alexandra Imre, Renátó Kovács, Kitti Pázmándi, Dániel Nemes, Ágnes Jakab, Tünde Fekete, Hanna Viktória Rácz, Ilona Dóczi, Ildikó Bácskay, Attila Gácser, Károly Kovács, László Majoros, Zoltán Farkas, István Pócsi, Walter P. Pfliegler
Pubblicato in: Journal of Fungi, Numero 7/9, 2021, Pagina/e 746, ISSN 2309-608X
Editore: Journal of Fungi
DOI: 10.3390/jof7090746

Chloroplastic ascorbate modifies plant metabolism and may act as a metabolite signal regardless of oxidative stress

Autori: Dávid Tóth, Roland Tengölics, Fayezeh Aarabi, Anna Karlsson, André Vidal-Meireles, László Kovács, Soujanya Kuntam, Tímea Körmöczi, Alisdair R Fernie, Elton P Hudson, Balázs Papp, Szilvia Z Tóth
Pubblicato in: Plant Physiology, 2024, ISSN 0032-0889
Editore: American Society of Plant Biologists
DOI: 10.1093/plphys/kiae409

In situ lymphoma imaging in a spontaneous mouse model using the Cerenkov Luminescence of F-18 and Ga-67 isotopes.

Autori: Ritter, Z., Zámbó, K., Balogh, P., Szöllösi, D., Xinkai, J., Balázs, Á., Taba, G., Dezső, D., Horváth, I., Hussain, A., Tuch, D., Vyas, K., Hegedűs, N., Kovács, T., Szigeti, K., Máthé D.,Schmidt, E.
Pubblicato in: Scientific reports, 2021, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-021-03505-3

High fat diet and PCSK9 knockout modulates lipid profile of the liver and changes the expression of lipid homeostasis related genes.

Autori: Németh K, Tóth B, Sarnyai F, Koncz A, Lenzinger D, Kereszturi É, Visnovitz T, Kestecher BM, Osteikoetxea X, Csala M, Buzás EI, Tamási V.
Pubblicato in: Nutrition and Metabolism, 2023, ISSN 1743-7075
Editore: BioMed Central
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Epigenetic Mechanisms of ART-Related Imprinting Disorders: Lessons from iPSC and Mouse Models

Autori: Alex Horánszky, Jessica L. Becker, Melinda Zana, Anne C. Ferguson-Smith, András Dinnyés
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Potential role of MAP2K1 mutation in the trans-differentiation of interdigitating dendritic cell sarcoma: Case report and literature review.

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Droplet Digital PCR Is a Novel Screening Method Identifying Potential Cardiac G-Protein-Coupled Receptors as Candidate Pharmacological Targets in a Rat Model of Pressure-Overload-Induced Cardiac Dysfunction.

Autori: Sayour NV, Tóth VÉ, Nagy RN, Vörös I, Gergely TG, Onódi Z, Nagy N, Bödör C, Váradi B, Ruppert M, Radovits T, Bleckwedel F, Zelarayán LC, Pacher P, Ágg B, Görbe A, Ferdinandy P, Varga ZV. Droplet
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Spinocerebellar Ataxia in a Hungarian Female Patient with a Novel Variant of Unknown Significance in the CCDC88C Gene.

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Pubblicato in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
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NASH triggers cardiometabolic HFpEF in aging mice.

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Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan.

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A dual role of lysophosphatidic acid type 2 receptor (LPAR2) in nonsteroidal anti-inflammatory drug-induced mouse enteropathy.

Autori: Hutka B, Várallyay A, László SB, Tóth AS, Scheich B, Paku S, Vörös I, Pós Z, Varga ZV, Norman DD, Balogh A, Benyó Z, Tigyi G, Gyires K, Zádori ZS.
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Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility.

Autori: White R, Sotillo J, Ancarola ME, Borup A, Boysen AT, Brindley PJ, Buzás EI, Cavallero S, Chaiyadet S, Chalmers IW, Cucher MA, Dagenais M, Davis CN, Devaney E, Duque-Correa MA, Eichenberger RM, Fontenla S, Gasan TA, Hokke CH, Kosanovic M, Kuipers ME, Laha T, Loukas A, Maizels RM, Marcilla A, Mazanec H, Morphew RM, Neophytou K, Nguyen LT, Nolte-'t Hoen E, Povelones M, Robinson MW, Rojas A, Schabuss
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Transcriptome and proteome profiling reveals complex adaptations of Candida parapsilosis cells assimilating hydroxyaromatic carbon sources.

Autori: Cillingová A, Tóth R, Mojáková A, Zeman I, Vrzoňová R, Siváková B, Baráth P, Neboháčová M, Klepcová Z, Brázdovič F, Lichancová H, Hodorová V, Brejová B, Vinař T, Mutalová S, Vozáriková V, Mutti G, Tomáška Ľ, Gácser A, Gabaldón T, Nosek J.
Pubblicato in: Plos Genetics, 2022, ISSN 1553-7390
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Cross-Linking Mass Spectrometry on P-Glycoprotein.

Autori: Gellen G, Klement E, Biwott K, Schlosser G, Kalló G, Csősz É, Medzihradszky KF, Bacso Z.
Pubblicato in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
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Erratum to: P459 Expression of SerpinE1, a potential new disease activity marker, reflects therapeutic response in Inflammatory Bowel Disease.

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The psoriatic non-lesional skin: a battlefield of constant fight between susceptibility and protective factors

Autori: Evelyn Kelemen, Renáta Bozó, Gergely Groma, Zsuzsanna Bata-Csörgő, Lajos Kemény, Judit Danis, Márta Széll
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In planta test system for targeted cellular mutagenesis by injection of oligonucleotides to apical meristem of maize seedlings

Autori: Feríz Rádi, Bettina Nagy, Györgyi Ferenc, Katalin Török, István Nagy, Zoltán Zombori, Dénes Dudits, Ferhan Ayaydin
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Small extracellular vesicle DNA-mediated horizontal gene transfer as a driving force for tumor evolution: Facts and riddles.

Autori: Valcz G, Újvári B, Buzás EI, Krenács T, Spisák S, Kittel Á, Tulassay Z, Igaz P, Takács I, Molnár B.
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The Utilization of Physiologically Active Molecular Components of Grape Seeds and Grape Marc.

Autori: Hegedüs I, Andreidesz K, Szentpéteri JL, Kaleta Z, Szabó L, Szigeti K, Gulyás B, Padmanabhan P, Budan F, Máthé D.
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Nod-Like Receptors in Host Defence and Disease at the Epidermal Barrier

Autori: Judit Danis, Mark Mellett
Pubblicato in: International Journal of Molecular Sciences, Numero 22/9, 2021, Pagina/e 4677, ISSN 1422-0067
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Donor Pericardial Interleukin and Apolipoprotein Levels May Predict the Outcome after Human Orthotopic Heart Transplantation.

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The DREAM complex represses growth in response to DNA damage in Arabidopsis

Autori: Lucas Lang, Aladár Pettkó-Szandtner, Hasibe Tunçay Elbaşı, Hirotomo Takatsuka, Yuji Nomoto, Ahmad Zaki, Stefan Dorokhov, Geert De Jaeger, Dominique Eeckhout, Masaki Ito, Zoltán Magyar, László Bögre, Maren Heese, Arp Schnittger
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Development of a Laser Microdissection-Coupled Quantitative Shotgun Lipidomic Method to Uncover Spatial Heterogeneity

Autori: Vanda Varga-Zsíros, Ede Migh, Annamária Marton, Zoltán Kóta, Csaba Vizler, László Tiszlavicz, Péter Horváth, Zsolt Török, László Vígh, Gábor Balogh, Mária Péter
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Microbiome's Universe: Impact on health, disease and cancer treatment

Autori: Zsuzsánna Réthi-Nagy, Szilvia Juhász
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Prognostic potential of CUL3 ligase with differential roles in luminal A and basal type breast cancer tumors

Autori: Vasiliki Pantazi, Vanda Miklós, Paul Smith, Orsolya Oláh-Németh, Gabriella Pankotai-Bodó, Divya Teja Dondapati, Ferhan Ayaydin, Vincenzo D’Angiolella, Tibor Pankotai
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Phytochrome C and Low Temperature Promote the Protein Accumulation and Red-Light Signaling of Phytochrome D

Autori: Csaba Péter, Éva Ádám, Cornelia Klose, Gábor Grézal, Anita Hajdu, Gábor Steinbach, László Kozma-Bognár, Dániel Silhavy, Ferenc Nagy, András Viczián
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Psoriatic Resolved Skin Epidermal Keratinocytes Retain Disease-Residual Transcriptomic and Epigenomic Profiles.

Autori: Ghaffarinia A, Ayaydin F, Póliska S, Manczinger M, Bolla BS, Flink LB, Balogh F, Veréb Z, Bozó R, Szabó K, Bata-Csörgő Z, Kemény L.
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MITF regulates IDH1, NNT, and a transcriptional program protecting melanoma from reactive oxygen species

Autori: Elisabeth Roider, Alexandra I. T. Lakatos, Alicia M. McConnell, Poguang Wang, Alina Mueller, Akinori Kawakami, Jennifer Tsoi, Botond L. Szabolcs, Anna A. Ascsillán, Yusuke Suita, Vivien Igras, Jennifer A. Lo, Jennifer J. Hsiao, Rebecca Lapides, Dorottya M. P. Pál, Anna S. Lengyel, Alexander Navarini, Arimichi Okazaki, Othon Iliopoulos, István Németh, Thomas G. Graeber, Leonard Zon, Roger W. Gi
Pubblicato in: Scientific Reports, Numero 14, 2024, ISSN 2045-2322
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Engineered Cas9 extracellular vesicles as a novel gene editing tool.

Autori: Osteikoetxea X, Silva A, Lázaro-Ibáñez E, Salmond N, Shatnyeva O, Stein J, Schick J, Wren S, Lindgren J, Firth M, Madsen A, Mayr LM, Overman R, Davies R, Dekker N.
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Non-coding Natural Antisense Transcripts: Analysis and Application

Autori: Julian C. Krappinger, Lilli Bonstingl, Katrin Pansy, Katja Sallinger, Nick I. Wreglesworth, Lukas Grinninger, Alexander Deutsch, Amin El-Heliebi, Thomas Kroneis, Ramsay J. Mcfarlane, Christoph W. Sensen, Julia Feichtinger
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Optimization of CFTR gating through the evolution of its extracellular loops.

Autori: Simon MA, Csanády L.
Pubblicato in: Journal of General Physiology, 2023, ISSN 0022-1295
Editore: Rockefeller University Press
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Circulating cardiomyocyte-derived extracellular vesicles reflect cardiac injury during systemic inflammatory response syndrome in mice.

Autori: Hegyesi H, Pallinger É, Mecsei S, Hornyák B, Kovácsházi C, Brenner GB, Giricz Z, Pálóczi K, Kittel Á, Tóvári J, Turiak L, Khamari D, Ferdinandy P, Buzás EI.
Pubblicato in: Cellular and Molecular Life Sciences, 2022, ISSN 1431-1941
Editore: Springer Nature
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Small paraquat resistance proteins modulate paraquat and ABA responses and confer drought tolerance to overexpressing Arabidopsis plants.

Autori: Faragó D, Zsigmond L, Benyó D, Alcazar R, Rigó G, Ayaydin F, Rabilu SA, Hunyadi-Gulyás É, Szabados L
Pubblicato in: Plant, Cell and Environment, 2022, ISSN 0140-7791
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Heavy metals in cigarette smoke strongly inhibit pancreatic ductal function and promote development of chronic pancreatitis

Autori: Petra Pallagi, Emese Tóth, Marietta Görög, Viktória Venglovecz, Tamara Madácsy, Árpád Varga, Tünde Molnár, Noémi Papp, Viktória Szabó, Enikő Kúthy‐Sutus, Réka Molnár, Attila Ördög, Katalin Borka, Andrea Schnúr, Albert Kéri, Gyula Kajner, Kata Csekő, Emese Ritter, Dezső Csupor, Zsuzsanna Helyes, Gábor Galbács, Andrea Szentesi, László Czakó, Zoltán Rakonczay, Tamás Tak
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Widespread alterations in microRNA biogenesis in human Huntington's disease putamen.

Autori: Petry S, Keraudren R, Nateghi B, Loiselle A, Pircs K, Jakobsson J, Sephton C, Langlois M, St-Amour I, Hébert SS.
Pubblicato in: Acta neuropathologica communications, 2022, ISSN 2051-5960
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Predictive Potential of RNA Polymerase B (II) Subunit 1 (RPB1) Cytoplasmic Aggregation for Neoadjuvant Chemotherapy Failure.

Autori: Nagy-Mikó B, Németh-Szatmári O, Faragó-Mészáros R, Csókási A, Bognár B, Ördög N, Borsos BN, Majoros H, Ujfaludi Z, Oláh-Németh O, Nikolényi A, Dobi Á, Kószó R, Sántha D, Lázár G, Simonka Z, Paszt A, Ormándi K, Pankotai T, Boros IM, Villányi Z, Vörös A.
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Limited Evolutionary Conservation of the Phenotypic Effects of Antibiotic Resistance Mutations

Autori: Gábor Apjok, Gábor Boross, Ákos Nyerges, Gergely Fekete, Viktória Lázár, Balázs Papp, Csaba Pál, Bálint Csörgő
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Genetic Characterization of Primary Mediastinal B-Cell Lymphoma: Pathogenesis and Patient Outcomes.

Autori: Noerenberg D, Briest F, Hennch C, Yoshida K, Hablesreiter R, Takeuchi Y, Ueno H, Staiger AM, Ziepert M, Asmar F, Locher BN, Toth E, Weber T, Amini RM, Klapper W, Bouzani M, Poeschel V, Rosenwald A, Held G, Campo E, Ishaque N, Stamatopoulos K, Kanellis G, Anagnostopoulos I, Bullinger L, Goldschmidt N, Zinzani PL, Bödör C, Rosenquist R, Vassilakopoulos TP, Ott G, Ogawa S, Damm F.
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Identifying Suitable Reference Gene Candidates for Quantification of DNA Damage-Induced Cellular Responses in Human U2OS Cell Culture System.

Autori: Barta N, Ördög N, Pantazi V, Berzsenyi I, Borsos BN, Majoros H, Páhi ZG, Ujfaludi Z, Pankotai T.
Pubblicato in: Biomolecules, 2023, ISSN 2218-273X
Editore: MDPI
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Profiling of Copy Number Alterations Using Low-Coverage Whole-Genome Sequencing Informs Differential Diagnosis and Prognosis in Primary Cutaneous Follicle Center Lymphoma.

Autori: Bátai, B., Kiss, L., Varga, L., Nagy, Á., Househam, J., Baker, A. M., László, T., Udvari, A., Horváth, R., Nagy, T., Csomor, J., Szakonyi, J., Schneider, T., Graham, T. A., Alpár, D., Fitzgibbon, J., Szepesi, Á., & Bödör, C.
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Identification of an NF1 Microdeletion with Optical Genome Mapping.

Autori: Büki G, Bekő A, Bödör C, Urbán P, Németh K, Hadzsiev K, Fekete G, Kehrer-Sawatzki H, Bene J.
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Editore: Multidisciplinary Digital Publishing Institute (MDPI)
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Are the Cutaneous Microbiota a Guardian of the Skin's Physical Barrier? The Intricate Relationship between Skin Microbes and Barrier Integrity.

Autori: Szabó K, Bolla BS, Erdei L, Balogh F, Kemény L.
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Editore: Multidisciplinary Digital Publishing Institute (MDPI)
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Characterization of the CDAA Diet-Induced Non-alcoholic Steatohepatitis Model: Sex-Specific Differences in Inflammation, Fibrosis, and Cholesterol Metabolism in Middle-Aged Mice

Autori: Dániel Kucsera, Viktória E. Tóth, Dorottya Gergő, Imre Vörös, Zsófia Onódi, Anikó Görbe, Péter Ferdinandy, Zoltán V. Varga
Pubblicato in: Frontiers in Physiology, Numero 12, 2021, ISSN 1664-042X
Editore: Frontiers Research Foundation
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Physical prehabilitation improves the postoperative outcome of associating liver partition and portal vein ligation for staged hepatectomy in experimental model.

Autori: Daradics N, Levay K, Horvath I, Kovacs N, Mathe D, Szigeti K, Szijarto A, Fulop A.
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Molecular Network Approach Reveals Rictor as a Central Target of Cardiac ProtectomiRs

Autori: András Makkos, Bence Ágg, Zoltán V. Varga, Zoltán Giricz, Mariann Gyöngyösi, Dominika Lukovic, Rainer Schulz, Monika Barteková, Anikó Görbe, Péter Ferdinandy
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Image-based and machine learning-guided multiplexed serology test for SARS-CoV-2.

Autori: Pietiäinen V, Polso M, Migh E, Guckelsberger C, Harmati M, Diosdi A, Turunen L, Hassinen A, Potdar S, Koponen A, Sebestyen EG, Kovacs F, Kriston A, Hollandi R, Burian K, Terhes G, Visnyovszki A, Fodor E, Lacza Z, Kantele A, Kolehmainen P, Kakkola L, Strandin T, Levanov L, Kallioniemi O, Kemeny L, Julkunen I, Vapalahti O, Buzas K, Paavolainen L, Horvath P, Hepojoki J.
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Transcriptional Analysis-Based Alterations Affecting Neuritogenesis of the Peripheral Nervous System in Psoriasis

Autori: Romhányi D, Szabó K, Kemény L, Sebestyén E, Groma G.
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Activated polymorphonuclear derived extracellular vesicles are potential biomarkers of periprosthetic joint infection.

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Correlations Between the Expression of Stromal Cell Activation Related Biomarkers, L-NGFR, Phospho-ERK1-2 and CXCL12, and Primary Myelofibrosis Progression.

Autori: Szekely T, Krenacs T, Maros ME, Bodor C, Daubner V, Csizmadia A, Vrabely B, Timar B.
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Three-dimensional bioprinting of functional β-islet-like constructs.

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Oscillotherapeutics – Time-targeted interventions in epilepsy and beyond

Autori: Yuichi Takeuchi, Antal Berényi
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Brain-derived neurotrophic factor increases cell number of neural progenitor cells derived from human induced pluripotent stem cells

Autori: Panetha Pansri, Phetcharat Phanthong, Nopparat Suthprasertporn, Yindee Kitiyanant, Alisa Tubsuwan, Andras Dinnyes, Julianna Kobolak, Narisorn Kitiyanant
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Hunting Out the autophagic problem in Huntington disease.

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A journey to your self: The vague definition of immune self and its practical implications

Autori: Balázs Koncz, Gergő Mihály Balogh, Máté Manczinger
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Stress-Related Regulation Is Abnormal in the Psoriatic Uninvolved Skin

Autori: Renáta Bozó, Judit Danis, Lili Borbála Flink, Dániel László Vidács, Lajos Kemény, Zsuzsanna Bata-Csörgő
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Cardioprotective microRNAs (protectomiRs) in a pig model of acute myocardial infarction and cardioprotection by ischaemic conditioning: MiR‐450a

Autori: Regina N. Nagy, András Makkos, Tamás Baranyai, Zoltán Giricz, Márta Szabó, Bernadett Kravcsenko‐Kiss, Zoltán Bereczki, Bence Ágg, László G. Puskás, Nóra Faragó, Rainer Schulz, Mariann Gyöngyösi, Dominika Lukovic, Zoltán V. Varga, Anikó Görbe, Péter Ferdinandy
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Establishment and characterization of a novel human induced pluripotent stem cell line stably expressing the iRFP720 reporter.

Autori: Fehér A, Schnúr A, Muenthaisong S, Bellák T, Ayaydin F, Várady G, Kemter E, Wolf E, Dinnyés A.
Pubblicato in: Scientific Reports, 2022, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-022-12956-1

Systematic review and network analysis of microRNAs involved in cardioprotection against myocardial ischemia/reperfusion injury and infarction: Involvement of redox signalling

Autori: András Makkos, Bence Ágg, Balázs Petrovich, Zoltán V. Varga, Anikó Görbe, Péter Ferdinandy
Pubblicato in: Free Radical Biology and Medicine, Numero 172, 2021, Pagina/e 237-251, ISSN 0891-5849
Editore: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2021.04.034

SerpinB2 is involved in cellular response upon UV irradiation

Autori: Hajnalka Majoros, Zsuzsanna Ujfaludi, Barbara Nikolett Borsos, Viktória Vivien Hudacsek, Zita Nagy, Frederic Coin, Krisztina Buzas, Ilona Kovács, Tamás Bíró, Imre Miklós Boros, Tibor Pankotai
Pubblicato in: Scientific Reports, Numero 9/1, 2019, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-019-39073-w

Editorial: The Role of Nuclear Molecules in the Pathogenesis of Autoimmune Disease

Autori: David S. Pisetsky, Reinhard Voll, Edit I. Buzas
Pubblicato in: Frontiers in Immunology, Numero 12, 2021, ISSN 1664-3224
Editore: Frontiers Media S.A.
DOI: 10.3389/fimmu.2021.737923

Quantitative Biodistribution of OMVs Using SPECT/CT Imaging with HYNIC-Duramycin Radiolabeling

Autori: Dávid Szöllősi, Polett Hajdrik, Hedvig Tordai, Ralf Bergmann, Ildikó Horváth, Judith Mihály, Anikó Gaál, Bálint Jezsó, Kanni Das Shailaja, Tamás Felföldi, Parasuraman Padmanabhan, Balázs Zoltán Gulyás, Domokos Máthé, Zoltán Varga, Krisztián Szigeti
Pubblicato in: ACS Omega, Numero 9, 2024, Pagina/e 42808-42813, ISSN 2470-1343
Editore: American Chemical Society
DOI: 10.1021/acsomega.4c04632

Thiopurines impair the apical plasma membrane expression of CFTR in pancreatic ductal cells via RAC1 inhibition.

Autori: Tél B, Papp N, Varga Á, Szabó V, Görög M, Susánszki P, Crul T, Kis A, Sendstad IH, Bagyánszki M, Bódi N, Hegyi P, Maléth J, Pallagi P.
Pubblicato in: Cellular and Molecular Life Sciences, 2023, ISSN 1420-682X
Editore: Birkhauser Verlag
DOI: 10.1007/s00018-022-04662-y

Novel actionable ROS1::GIT2 fusion in non-Langerhans cell histiocytosis with central nervous system involvement.

Autori: Bedics G, Csóka M, Reiniger L, Varga E, Liptai Z, Papp G, Bekő A, Cervi C, Bödör C, Scheich B.
Pubblicato in: Acta neuropathologica communications, Numero 20515960, 2022, ISSN 2051-5960
Editore: BioMed Central
DOI: 10.1007/s00401-022-02520-6

Anti-PD-1 Therapy Does Not Influence Hearing Ability in the Most Sensitive Frequency Range, but Mitigates Outer Hair Cell Loss in the Basal Cochlear Region

Autori: Judit Szepesy, Gabriella Miklós, János Farkas, Dániel Kucsera, Zoltán Giricz, Anita Gáborján, Gábor Polony, Ágnes Szirmai, László Tamás, László Köles, Zoltán V. Varga, Tibor Zelles
Pubblicato in: International Journal of Molecular Sciences, Numero 21/18, 2020, Pagina/e 6701, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21186701

Revealing a Phenotypical Appearance of Ibrutinib Resistance in Patients With Chronic Lymphocytic Leukaemia by Flow Cytometry.

Autori: Takács F, Kotmayer L, Czeti Á, Szalóki G, László T, Mikala G, Márk Á, Masszi A, Farkas P, Plander M, Weisinger J, Demeter J, Fekete S, Szerafin L, Deák BM, Szaleczky E, Sulák A, Borbényi Z, Barna G.
Pubblicato in: Pathology and Oncology Research, Numero 15322807, 2022, ISSN 1532-2807
Editore: Frontiers Media S.A.
DOI: 10.3389/pore.2022.1610659

Fluorescent, Prussian Blue-Based Biocompatible Nanoparticle System for Multimodal Imaging Contrast

Autori: László Forgách, Nikolett Hegedűs, Ildikó Horváth, Bálint Kiss, Noémi Kovács, Zoltán Varga, Géza Jakab, Tibor Kovács, Parasuraman Padmanabhan, Krisztián Szigeti, Domokos Máthé
Pubblicato in: Nanomaterials, Numero 10/9, 2020, Pagina/e 1732, ISSN 2079-4991
Editore: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/nano10091732

Simple binding of protein kinase A prior to phosphorylation allows CFTR anion channels to be opened by nucleotides

Autori: Csaba Mihályi, Iordan Iordanov, Beáta Töröcsik, László Csanády
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 117/35, 2020, Pagina/e 21740-21746, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2007910117

PersonALL: a genetic scoring guide for personalized risk assessment in pediatric B-cell precursor acute lymphoblastic leukemia.

Autori: Kelemen Á, Sebestyén E, Jakab Z, Matolcsy A, Kiss C, Kovács G, Savola S, Bödör C, Alpár D.
Pubblicato in: British Journal of Cancer, 2023, ISSN 1532-1827
Editore: Nature Publishing Group
DOI: 10.1038/s41416-023-02309-8

Extracellular vesicles promote migration despite BRAF inhibitor treatment in malignant melanoma cells

Autori: Afrodité Németh, Gréta L. Bányai, Nikolett K. Dobos, Tamás Kós, Anikó Gaál, Zoltán Varga, Edit I. Buzás, Delaram Khamari, Magdolna Dank, István Takács, A. Marcell Szász, Tamás Garay
Pubblicato in: Cell Communication and Signaling, Numero 22, 2024, ISSN 1478-811X
Editore: BioMed Central
DOI: 10.1186/s12964-024-01660-4

Olive Oil Improves While Trans Fatty Acids Further Aggravate the Hypomethylation of LINE-1 Retrotransposon DNA in an Environmental Carcinogen Model. Nutrients.

Autori: Szabo L, Molnar R, Tomesz A, Deutsch A, Darago R, Varjas T, Ritter Z, Szentpeteri JL, Andreidesz K, Mathe D, Hegedüs I, Sik A, Budan F, Kiss I.
Pubblicato in: Nutrients, 2022, ISSN 2072-6643
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu14040908

Wnt Activity and Cell Proliferation Are Coupled to Extracellular Vesicle Release in Multiple Organoid Models

Autori: Gyöngyvér Orsolya Sándor, András Áron Soós, Péter Lörincz, Lívia Rojkó, Tünde Harkó, Levente Bogyó, Tamás Tölgyes, Attila Bursics, Edit I. Buzás, Judit Moldvay, Zoltán Wiener
Pubblicato in: Frontiers in Cell and Developmental Biology, Numero 9, 2021, ISSN 2296-634X
Editore: Frontiers Media S.A.
DOI: 10.3389/fcell.2021.670825

Questioning Glutamate Excitotoxicity in Acute Brain Damage: The Importance of Spreading Depolarization. Neurocrit Care.

Autori: Andrew RD, Farkas E, Hartings JA, Brennan KC, Herreras O, Müller M, Kirov SA, Ayata C, Ollen-Bittle N, Reiffurth C, Revah O, Robertson RM, Dawson-Scully KD, Ullah G, Dreier JP.
Pubblicato in: Neurocritical care, 2022, ISSN 1556-0961
Editore: Springer Nature
DOI: 10.1007/s12028-021-01429-4

Alzheimer’s Disease: A Molecular View of β-Amyloid Induced Morbific Events

Autori: Rajmohamed Mohamed Asik, Natarajan Suganthy, Mohamed Asik Aarifa, Arvind Kumar, Krisztián Szigeti, Domokos Mathe, Balázs Gulyás, Govindaraju Archunan, Parasuraman Padmanabhan
Pubblicato in: Biomedicines, Numero 9/9, 2021, Pagina/e 1126, ISSN 2227-9059
Editore: MDPI AG
DOI: 10.3390/biomedicines9091126

"Unraveling Transcriptome Profile, Epigenetic Dynamics, and Morphological Changes in Psoriasis-like Keratinocytes: ""Insights into Similarity with Psoriatic Lesional Epidermis"""

Autori: Ghaffarinia A, Póliska S, Ayaydin F, Goblos A, Parvaneh S, Manczinger M, Balogh F, Erdei L, Veréb Z, Szabó K, Bata-Csörgő Z, Kemény L.
Pubblicato in: Cells, 2023, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells12242825

Altered Cellular Protein Quality Control System Modulates Cardiomyocyte Function in Volume Overload-Induced Hypertrophy.

Autori: Gömöri K, Herwig M, Hassoun R, Budde H, Mostafi N, Delalat S, Modi S, Begovic M, Szabados T, Pipis J, Farkas-Morvay N, Leprán I, Kovács Á, Mügge A, Ferdinandy P, Görbe A, Bencsik P, Hamdani N.
Pubblicato in: Atioxidants, Numero 20763921, 2022, ISSN 2076-3921
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/antiox11112210

Effect of Inflammatory Microenvironment on the Regenerative Capacity of Adipose-Derived Mesenchymal Stem Cells

Autori: Diána Szűcs, Vanda Miklós, Tamás Monostori, Melinda Guba, Anikó Kun-Varga, Szilárd Póliska, Erika Kis, Balázs Bende, Lajos Kemény, Zoltán Veréb
Pubblicato in: Cells, Numero 12, 2023, Pagina/e 1966, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells12151966

Delayed Contralateral Nephrectomy Halted Post-Ischemic Renal Fibrosis Progression and Inhibited the Ischemia-Induced Fibromir Upregulation in Mice

Autori: Beáta Róka, Pál Tod, Tamás Kaucsár, Éva Nóra Bukosza, Imre Vörös, Zoltán V. Varga, Balázs Petrovich, Bence Ágg, Péter Ferdinandy, Gábor Szénási, Péter Hamar
Pubblicato in: Biomedicines, Numero 9/7, 2021, Pagina/e 815, ISSN 2227-9059
Editore: MDPI AG
DOI: 10.3390/biomedicines9070815

Degenerate but indispensable: how CFTR channel activity depends on the catalytically inactive ATP binding site?

Autori: László Csanády
Pubblicato in: The Journal of Physiology, 2021, ISSN 0022-3751
Editore: Blackwell Publishing Inc.
DOI: 10.1113/jp282278

Nimodipine augments cerebrovascular reactivity in aging but runs the risk of local perfusion reduction in acute cerebral ischemia

Autori: Szilvia Kecskés, Ákos Menyhárt, Ferenc Bari, Eszter Farkas
Pubblicato in: Frontiers in Aging Neuroscience, Numero 15, 2023, ISSN 1663-4365
Editore: Frontiers Research Foundation
DOI: 10.3389/fnagi.2023.1175281

Transient Hypoperfusion to Ischemic/Anoxic Spreading Depolarization is Related to Autoregulatory Failure in the Rat Cerebral Cortex

Autori: Menyhárt Á, Varga DP, M Tóth O, Makra P, Bari F, Farkas E.
Pubblicato in: Transient Hypoperfusion to Ischemic/Anoxic Spreading Depolarization is Related to Autoregulatory Failure in the Rat Cerebral Cortex., 2021, ISSN 1556-0961
Editore: Springer Nature
DOI: 10.1007/s12028-021-01393-z

Stellaria media tea protects against diabetes-induced cardiac dysfunction in rats without affecting glucose tolerance.

Autori: Demján V, Sója A, Kiss T, Fejes A, Gausz D, Szűcs G, Siska A, Földesi I, Tengölics R, Darula Zs, Csupor D, Pipicz M, Csont T.
Pubblicato in: JTCM Journal of Traditional and Complementary Medicine, 2021, ISSN 2225-4110
Editore: Medknow Publications and Media Pvt. Ltd
DOI: 10.1016/j.jtcme.2021.08.003

The roles of extracellular vesicles in the immune system.

Autori: Buzas EI.
Pubblicato in: Nature Reviews Immunology, 2022, ISSN 1474-1733
Editore: Nature Publishing Group
DOI: 10.1038/s41577-022-00763-8

Interplay of Oxidative Stress and Necrosis-like Cell Death in Cardiac Ischemia/Reperfusion Injury: A Focus on Necroptosis.

Autori: Adameova A, Horvath C, Abdul-Ghani S, Varga ZV, Suleiman MS, Dhalla NS.
Pubblicato in: Biomedicines, 2022, ISSN 2227-9059
Editore: MDPI AG
DOI: 10.3390/biomedicines10010127

Proteotranscriptomic Discrimination of Tumor and Normal Tissues in Renal Cell Carcinoma.

Autori: Bartha Á, Darula Z, Munkácsy G, Klement É, Nyirády P, Győrffy B.
Pubblicato in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24054488

Volatile anaesthetics inhibit the thermosensitive nociceptor ion channel transient receptor potential melastatin 3 (TRPM3)

Autori: Balázs Kelemen, Erika Lisztes, Anita Vladár, Martin Hanyicska, János Almássy, Attila Oláh, Attila Gábor Szöllősi, Zsófia Pénzes, János Posta, Thomas Voets, Tamás Bíró, Balázs István Tóth
Pubblicato in: Biochemical Pharmacology, Numero 174, 2020, Pagina/e 113826, ISSN 0006-2952
Editore: Elsevier BV
DOI: 10.1016/j.bcp.2020.113826

Bicarbonate Evokes Reciprocal Changes in Intracellular Cyclic di-GMP and Cyclic AMP Levels in Pseudomonas aeruginosa

Autori: Kasidid Ruksakiet, Balázs Stercz, Gergő Tóth, Pongsiri Jaikumpun, Ilona Gróf, Roland Tengölics, Zsolt M. Lohinai, Péter Horváth, Mária A. Deli, Martin C. Steward, Orsolya Dobay, Ákos Zsembery
Pubblicato in: Biology, Numero 10/6, 2021, Pagina/e 519, ISSN 2079-7737
Editore: MDPI
DOI: 10.3390/biology10060519

Shared extracellular vesicle miRNA profiles of matched ductal pancreatic adenocarcinoma organoids and blood plasma samples show the power of organoid technology

Autori: Anikó Zeöld, Gyöngyvér Orsolya Sándor, Anna Kiss, András Áron Soós, Tamás Tölgyes, Attila Bursics, Ákos Szűcs, László Harsányi, Ágnes Kittel, András Gézsi, Edit I. Buzás, Zoltán Wiener
Pubblicato in: Cellular and Molecular Life Sciences, 2020, ISSN 1420-682X
Editore: Birkhauser Verlag
DOI: 10.1007/s00018-020-03703-8

The IV International Symposium on Fungal Stress and the XIII International Fungal Biology Conference.

Autori: Alder-Rangel A, Bailão AM, Herrera-Estrella A, Rangel AEA, Gácser A, Gasch AP, Campos CBL, Peters C, Camelim F, Verde F, Gadd GM, Braus G, Eisermann I, Quinn J, Latgé JP, Aguirre J, Bennett JW, Heitman J, Nosanchuk JD, Partida-Martínez LP, Bassilana M, Acheampong MA, Riquelme M, Feldbrügge M, Keller NP, Keyhani NO, Gunde-Cimerman N, Nascimento R, Arkowitz RA, Mouriño-Pérez RR, Naz SA, Avery
Pubblicato in: Fungal Biology, 2023, ISSN 1096-0937
Editore: Academic Press Inc.
DOI: 10.1016/j.funbio.2023.04.006

Estimating the true stability of the prehydrolytic outward-facing state in an ABC protein.

Autori: Simon MA, Iordanov I, Szollosi A, Csanády L.
Pubblicato in: eLife, 2023, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.90736

Merkel K, Szöllősi D, Horváth I, Jezsó B, Baranyai Z, Szigeti K, Varga Z, Hegedüs I, Padmanabhan P, Gulyás B, Bergmann R, Máthé D.

Autori: Radiolabeling of Platelets with 99mTc-HYNIC-Duramycin for In Vivo Imaging Studies.
Pubblicato in: Internaitonal Journal of Molecular Sciences, 2023, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242317119

The Rad5 helicase and RING domains contribute to genome stability through their independent catalytic activities.

Autori: Toth R, Balogh D, Pinter L, Jaksa G, Szeplaki B, Graf A, Gyorfy Z, Zs Enyedi M, Kiss E, Haracska L, Unk I.
Pubblicato in: Journal of molecular biology, 2022, ISSN 0022-2836
Editore: Academic Press
DOI: 10.1016/j.jmb.2021.167437

IL-1β neutralization prevents diastolic dysfunction development, but lacks hepatoprotective effect in an aged mouse model of NASH.

Autori: Kucsera D, Tóth VE, Sayour NV, Kovács T, Gergely TG, Ruppert M, Radovits T, Fábián A, Kovács A, Merkely B, Ferdinandy P, Varga ZV.
Pubblicato in: Scientific Reports, 2023, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-022-26896-3

Characterization of Neurons Expressing the Novel Analgesic Drug Target Somatostatin Receptor 4 in Mouse and Human Brains

Autori: Angéla Kecskés, Krisztina Pohóczky, Miklós Kecskés, Zoltán V. Varga, Viktória Kormos, Éva Szőke, Nóra Henn-Mike, Máté Fehér, József Kun, Attila Gyenesei, Éva Renner, Miklós Palkovits, Péter Ferdinandy, István M. Ábrahám, Balázs Gaszner, Zsuzsanna Helyes
Pubblicato in: International Journal of Molecular Sciences, Numero 21/20, 2020, Pagina/e 7788, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21207788

Interdisciplinary Analyses of Bronze Age Communities from Western Hungary Reveal Complex Population Histories.

Autori: Gerber D, Szeifert B, Székely O, Egyed B, Gyuris B, Giblin JI, Horváth A, Köhler K, Kulcsár G, Kustár Á, Major I, Molnár M, Palcsu L, Szeverényi V, Fábián S, Mende BG, Bondár M, Ari E, Kiss V, Szécsényi-Nagy A.
Pubblicato in: Molecular Biology and Evolution, 2023, ISSN 1537-1719
Editore: Oxford University Press
DOI: 10.1093/molbev/msad182

IDENTIFICATION OF NEGATIVE REGULATORS OF THE CUTIBACTERIUM ACNES-INDUCED INNATE IMMUNE ACTIVATION IN HUMAN EPIDERMAL KERATINOCYTES

Autori: Lilla Erdei
Pubblicato in: 2020
Editore: -

Targeting IL-1β and assessing sex-specific molecular differences in mouse models of non-alcoholic steatohepatitis

Autori: Dániel Kucsera
Pubblicato in: 2023
Editore: -

Immune-inflammatory targets in chronic heart failure: inflammasomes and the endocannabinoid system

Autori: Zsófia Gulyás-Onódi
Pubblicato in: 2022
Editore: Semmelweis University

Orai1 calcium channel inhibition prevents progression of chronic pancreatitis

Autori: Viktória Szabó
Pubblicato in: 2023
Editore: -

Értekezés címe: Az in vivo fehérjeaggregáció útvonalait befolyásoló tényezők vizsgálata Escherichia coliban

Autori: Györkei Ádám
Pubblicato in: 2022
Editore: -

Negative trade-off between neoantigen repertoire breadth and the specificity of HLA-I molecules shapes antitumor immunity

Autori: Balogh Gergő Mihály
Pubblicato in: 2023
Editore: -

Discovery of small-molecule inhibitors of Rad6 function and the Rad6-Rad18 interaction

Autori: Sharma Gaurav
Pubblicato in: 2023
Editore: -

A CFTR anioncsatorna extracelluláris régiójának a csatorna működésére gyakorolt hatása

Autori: Simon Márton András
Pubblicato in: 2023
Editore: -

Application of Circulating Tumor DNA Analysis for the Detection of EZH2 Mutations in Follicular Lymphoma

Autori: Nagy Ákos
Pubblicato in: 2023
Editore: -

BRCA1/2 patogén és ismeretlen klinikai szignifikanciájú variánsok azonosítása és vizsgálati lehetőségei

Autori: Gráf Alexandra
Pubblicato in: 2022
Editore: -

Inflammatory memory of Keratinocytes in psoriasis

Autori: Ameneh Ghaffarinia
Pubblicato in: 2024
Editore: -

The study of the membrane microdomain localization of the prion-family proteins, prion and Shadoo and their interaction with calnexin

Autori: Divya Teja Dondapati
Pubblicato in: 2022
Editore: University of Szeged

Genomic Profiling of Pediatric Malignant Haematopoietic and Lymphoid Diseases by NextGeneration Sequencing-based Methods and Bioinformatic Approaches

Autori: Gábor Bedics
Pubblicato in: 2024
Editore: -

Hipertermia-okozta stresszválasz molekuláris mechanizmusai emlős sejtekben

Autori: Tiszlavicz Ádám
Pubblicato in: 2022
Editore: -

Compensatory evolution as a driver of morphological novelties

Autori: Sarkadi Zsuzsa
Pubblicato in: 2022
Editore: -

Antitumor effects of modulated electro-hyperthermia in 4T1 triple-negative breast cancer models

Autori: Danics Lea Orsolya
Pubblicato in: 2021
Editore: -

Controlling cell polarity in human pancreatic organoids significantly improves the resolution of ex vivo physiological modeling

Autori: Varga Árpád
Pubblicato in: 2023
Editore: -

The relationship between PP4 phosphatase and Centrobin in late stages of DNA repair

Autori: Zsuzsánna Réthi-Nagy
Pubblicato in: 2023
Editore: -

Potential relevance of periostin in psoriasis

Autori: Lili Borbála Flink
Pubblicato in: 2024
Editore: -

Epigenetic consequences of in utero exposure to rosuvastatin include altered histone methylation patterns in newborn rat brains

Autori: Fábián-Dulka Karolina
Pubblicato in: 2021
Editore: University of Szeged

Molecular background of resistance to targeted therapies in chronic lymphocytic

Autori: Kotmayer Lili Eszter
Pubblicato in: 2023
Editore: -

Plasminogen activator inhibitor type 1, as a novel faecal biomarker in Inflammatory Bowel Diseases

Autori: Boldizsár Csaba Jójárt
Pubblicato in: 2024
Editore: -

Potential relevance of altered cartilage oligomeric matrix protein in psoriasis

Autori: Renáta Bozó
Pubblicato in: 2020
Editore: University of Szeged

Spatiotemporally precise targeting of memory processes to prevent and ameliorate maladaptive fear responses

Autori: Pedraza Correa Lyzeth Katherina
Pubblicato in: 2023
Editore: -

Discovery of small-molecule inhibitors of Uba1 and development of step-specific assays for PCNA ubiquitination

Autori: Paras Gaur
Pubblicato in: 2020
Editore: -

Neuropeptides in cardioprotection and cardiovascular diseases

Autori: Imre Vörös
Pubblicato in: 2024
Editore: -

A funkcionális metagenomika módszerének kiterjesztése kórokozó baktériumokra az antibiotikumrezisztencia vizsgálatának céljából

Autori: Számel Mónika
Pubblicato in: 2023
Editore: -

CFTR deficiency causes PMCA4 dysfunction, intracellular Ca2+ elevation and promotes epithelial cell damage in alcoholic pancreatitis and hepatitis

Autori: Tamara Éva Madácsy
Pubblicato in: 2022
Editore: University of Szeged

Vasculitides primarily involving the skin

Autori: Géza Róbert Nagy
Pubblicato in: 2020
Editore: University of Szeged

RAD18-dependent Activation of FAN1 by Ub-PCNA to Rescue DNA Interstrand crosslinks along with TLS Pol η

Autori: Qiuzhen Li
Pubblicato in: 2021
Editore: -

Bioanalytics, lipidomics and metabolomics application of one- and two-dimensional LC-MS techniques

Autori: Tímea Körmöczi
Pubblicato in: 2022
Editore: University of Szeged

The effect of Cutibacterium acnes on the barrier properties of in vitro cultured keratinocytes

Autori: Beáta Szilvia Bolla
Pubblicato in: 2020
Editore: University of Szeged

Szívelégtelenségben ható szerek

Autori: Ferdinandy Péter, Varga Zoltán In: Gyires Klára, Fürst Zsuzsanna, Ferdinandy Péter, Pintér Erika, Szilvássy Zoltán, Varró András (szerk.)
Pubblicato in: Farmakológia és klinikai farmakológia: egyetemi tankönyv, Numero p. 10, 2020, Pagina/e pp. 224-233
Editore: Medicina Könyvkiadó Zrt.

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