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Establishing the Hungarian Center of Excellence for Molecular Medicine in partnership with EMBL

Publications

Detection and Functional Evaluation of the P2X7 Receptor in hiPSC Derived Neurons and Microglia-Like Cells. Front Mol Neurosci

Author(s): Francistiová L, Vörös K, Lovász Z, Dinnyés A, Kobolák J.
Published in: Frontiers in molecular neuroscience, 2022, ISSN 1662-5099
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnmol.2021.793769

Regulation of Orai channels by intracellular pH: one step closer to understand CRAC channel biology? J Physiol.

Author(s): Maléth J.
Published in: Journal of Physiology, 2022, ISSN 1469-7793
Publisher: Wiley-Blackwell Publishing Ltd
DOI: 10.1113/jp282680

Sierra RO, Pedraza LK, Barcsai L, Pejin A, Li Q, Kozák G, Takeuchi Y, Nagy AJ, Lőrincz ML, Devinsky O, Buzsáki G, Berényi A.

Author(s): Closed-loop brain stimulation augments fear extinction in male rats. Nat Commun.
Published in: Nature Communications, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-39546-7

Phenotypic plasticity of melanocytes derived from human adult skin

Author(s): Dániel László Vidács, Zoltán Veréb, Renáta Bozó, Lili Borbála Flink, Hilda Polyánka, István Balázs Németh, Szilárd Póliska, Benjamin Tamás Papp, Máté Manczinger, Róbert Gáspár, Seyedmohsen Mirdamadi, Lajos Kemény, Zsuzsanna Bata‐Csörgő
Published in: Pigment Cell & Melanoma Research, 2021, ISSN 1755-1471
Publisher: Basil Blackwell
DOI: 10.1111/pcmr.13012

Next-Generation Sequencing-Based Genomic Profiling of Children with Acute Myeloid Leukemia.

Author(s): Krizsán S, Péterffy B, Egyed B, Nagy T, Sebestyén E, Hegyi LL, Jakab Z, Erdélyi DJ, Müller J, Péter G, Csanádi K, Kállay K, Kriván G, Barna G, Bedics G, Haltrich I, Ottóffy G, Csernus K, Vojcek Á, Tiszlavicz LG, Gábor KM, Kelemen Á, Hauser P, Gaál Z, Szegedi I, Ujfalusi A, Kajtár B, Kiss C, Matolcsy A, Tímár B, Kovács G, Alpár D, Bödör C.
Published in: Journal of Molecular Diagnostics, 2023, ISSN 1525-1578
Publisher: American Society for Investigative Pathology
DOI: 10.1016/j.jmoldx.2023.04.004

Herpes Simplex Virus Infection Alters the Immunological Properties of Adipose-Tissue-Derived Mesenchymal-Stem Cells.

Author(s): Kun-Varga A, Gubán B, Miklós V, Parvaneh S, Guba M, Szűcs D, Monostori T, Varga J, Varga Á, Rázga Z, Bata-Csörgő Z, Kemény L, Megyeri K, Veréb Z.
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms241511989

Candida albicans Enhances the Progression of Oral Squamous Cell Carcinoma In Vitro and In Vivo.

Author(s): Vadovics M, Ho J, Igaz N, Alföldi R, Rakk D, Veres É, Szücs B, Horváth M, Tóth R, Szücs A, Csibi A, Horváth P, Tiszlavicz L, Vágvölgyi C, Nosanchuk JD, Szekeres A, Kiricsi M, Henley-Smith R, Moyes DL, Thavaraj S, Brown R, Puskás LG, Naglik JR, Gácser A.
Published in: mBio, 2022, ISSN 2150-7511
Publisher: American Society for Microbiology
DOI: 10.1128/mbio.03144-21

Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.

Author(s): Mansouri L, Thorvaldsdottir B, Sutton LA, Karakatsoulis G, Meggendorfer M, Parker H, Nadeu F, Brieghel C, Laidou S, Moia R, Rossi D, Catherwood M, Kotaskova J, Delgado J, Rodríguez-Vicente AE, Benito R, Rigolin GM, Bonfiglio S, Scarfo L, Mattsson M, Davis Z, Gogia A, Rani L, Baliakas P, Foroughi-Asl H, Jylhä C, Skaftason A, Rapado I, Miras F, Martinez-Lopez J, de la Serna J, Rivas JMH, Thornton
Published in: Leukemia, 2022, ISSN 0887-6924
Publisher: Nature Publishing Group
DOI: 10.1038/s41375-022-01802-y

Characterization and functional analysis of zinc trafficking in the human fungal pathogen Candida parapsilosis.

Author(s): Takács T, Németh MT, Bohner F, Vágvölgyi C, Jankovics F, Wilson D, Gácser A.
Published in: Open biology, 2022, ISSN 2046-2441
Publisher: Royal Society Publishing
DOI: 10.1098/rsob.220077

Molecular pathology of the R117H cystic fibrosis mutation is explained by loss of a hydrogen bond.

Author(s): Simon MA, Csanády L.
Published in: eLife Sciences Publications, 2019, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.74693

Influence of cardiometabolic comorbidities on myocardial function, infarction, and CARDIOPROTECTION: Role of cardiac redox signaling

Author(s): Ioanna Andreadou, Andreas Daiber, Gary F. Baxter, Maria.Felice Brizzi, Fabio di Lisa, Nina Kaludercic, Antigone Lazou, Zoltán.V. Varga, Coert Zuurbier, Rainer Schulz, Péter Ferdinandy
Published in: Free Radical Biology and Medicine, 2021, ISSN 0891-5849
Publisher: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2021.02.012

Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes.

Author(s): Rönn T, Ofori JK, Perfilyev A, Hamilton A, Pircs K, Eichelmann F, Garcia-Calzon S, Karagiannopoulos A, Stenlund H, Wendt A, Volkov P, Schulze MB, Mulder H, Eliasson L, Ruhrmann S, Bacos K, Ling C.
Published in: Nature Communications, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-43719-9

Antineoplastic drugs inducing cardiac and vascular toxicity - An update.

Author(s): Barachini S, Ghelardoni S, Varga ZV, Mehanna RA, Montt-Guevara MM, Ferdinandy P, Madonna R.
Published in: Vascular Pharmacology, 2023, ISSN 1879-3649
Publisher: Elsevier
DOI: 10.1016/j.vph.2023.107223

The genomic landscape of teenage and young adult T‐cell acute lymphoblastic leukemia

Author(s): Marcela B. Mansur, Caroline L. Furness, Sirintra Nakjang, Amir Enshaei, Donat Alpar, Sue M. Colman, Lynne Minto, Julie Irving, Beth V. Poole, Elda P. Noronha, Suvi Savola, Sameena Iqbal, John Gribben, Maria S. Pombo‐de‐Oliveira, Tony M. Ford, Mel F. Greaves, Frederik W. Delft
Published in: Cancer Medicine, 2021, ISSN 2045-7634
Publisher: John Wiley and Sons Ltd
DOI: 10.1002/cam4.4024

Liquid biopsy-based monitoring of residual disease in multiple myeloma by analysis of the rearranged immunoglobulin genes-A feasibility study.

Author(s): Marx A, Osváth M, Szikora B, Pipek O, Csabai I, Nagy Á, Bödör C, Matula Z, Nagy G, Bors A, Uher F, Mikala G, Vályi-Nagy I, Kacskovics I.
Published in: PLoS One, 2023, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0285696

In Vitro Determination of Inhibitory Effects of Humic Substances Complexing Zn and Se on SARS-CoV-2 Virus Replication. Foods.

Author(s): Hajdrik P, Pályi B, Kis Z, Kovács N, Veres DS, Szigeti K, Budán F, Hegedüs I, Kovács T, Bergmann R, Máthé D.
Published in: Foods, 2022, ISSN 2304-8158
Publisher: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/foods11050694

Beta-lactamase dependent and independent evolutionary paths to high-level ampicillin resistance

Author(s): Rotem Gross, Idan Yelin, Viktória Lázár, Manoshi Sen Datta, Roy Kishony
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-49621-2

Synergism of red blood cells and tranexamic acid in the inhibition of fibrinolysis.

Author(s): Raska A, Kálmán K, Egri B, Csikós P, Beinrohr L, Szabó L, Tenekedjiev K, Nikolova N, Longstaff C, Roberts I, Kolev K, Wohner N.
Published in: Journal of Thrombosis and Haemostasis, 2023, ISSN 1538-7836
Publisher: Wiley-Blackwell Publishing Ltd
DOI: 10.1016/j.jtha.2023.11.009

TRAF3 and NBR1 both influence the effect of the disease‐causing CYLD(Arg936X) mutation on NF‐κB activity

Author(s): Judit Danis, Evelyn Kelemen, Neil Rajan, Nikoletta Nagy, Márta Széll, Éva Ádám
Published in: Experimental Dermatology, 2021, ISSN 0906-6705
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/exd.14365

Capturing time-dependent activation of genes and stress-response pathways using transcriptomics in iPSC-derived renal proximal tubule cells.

Author(s): Jennings P, Carta G, Singh P, da Costa Pereira D, Feher A, Dinnyes A, Exner TE, Wilmes A.
Published in: Cell Biology and Toxicology, 2022, ISSN 0742-2091
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10565-022-09783-5

Blue flash sheds light on the roles of individual phosphoserines in CFTR channel activation.

Author(s): Csanády L.
Published in: Journal of General Physiology, 2023, ISSN 0022-1295
Publisher: Rockefeller University Press
DOI: 10.1085/jgp.202313336

Cellular and Molecular Effects of SARS-CoV-2 Linking Lung Infection to the Brain

Author(s): Linda Francistiová, Adrián Klepe, Géza Curley, Károly Gulya, András Dinnyés, Kata Filkor
Published in: Frontiers in Immunology, Issue 12, 2021, ISSN 1664-3224
Publisher: Frontiers Media S.A.
DOI: 10.3389/fimmu.2021.730088

Extracellular Vesicle-Mediated Metastasis Suppressors NME1 and NME2 Modify Lipid Metabolism in Fibroblasts.

Author(s): Mátyási B, Petővári G, Dankó T, Butz H, Likó I, Lőw P, Petit I, Bittar R, Bonnefont-Rousselot D, Farkas Z, Szeniczey T, Molnár K, Pálóczi K, Buzás EI, Boissan M, Sebestyén A, Takács-Vellai K.
Published in: Cancers, 2022, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14163913

Application of Lacunarity for Quantification of Single Molecule Localization Microscopy Images.

Author(s): Kovács BBH, Varga D, Sebők D, Majoros H, Polanek R, Pankotai T, Hideghéty K, Kukovecz Á, Erdélyi M.
Published in: Cells, Issue 20734409, 2022, ISSN 2073-4409
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cells11193105

AIM2-driven inflammasome activation in heart failure

Author(s): Zsófia Onódi, Mihály Ruppert, Dániel Kucsera, Alex Ali Sayour, Viktória E Tóth, Gábor Koncsos, Julianna Novák, Gábor B Brenner, András Makkos, Tamás Baranyai, Zoltán Giricz, Anikó Görbe, Przemyslaw Leszek, Mariann Gyöngyösi, Iván G Horváth, Rainer Schulz, Béla Merkely, Péter Ferdinandy, Tamás Radovits, Zoltán V Varga
Published in: Cardiovascular Research, 2021, ISSN 0008-6363
Publisher: Elsevier BV
DOI: 10.1093/cvr/cvab202

Suboptimal global transcriptional response increases the harmful effects of loss-of-function mutations

Author(s): Károly Kovács, Zoltán Farkas, Djordje Bajić, Dorottya Kalapis, Andreea Daraba, Karola Almási, Bálint Kintses, Zoltán Bódi, Richard A Notebaart, Juan F Poyatos, Patrick Kemmeren, Frank C P Holstege, Csaba Pál, Balázs Papp
Published in: Molecular Biology and Evolution, 2020, ISSN 0737-4038
Publisher: Oxford University Press
DOI: 10.1093/molbev/msaa280

Adenosine Promotes Human Hair Growth and Inhibits Catagen Transition In Vitro: Role of the Outer Root Sheath Keratinocytes

Author(s): Erika Lisztes, Balázs István Tóth, Marta Bertolini, Imre Lőrinc Szabó, Nóra Zákány, Attila Oláh, Attila Gábor Szöllősi, Ralf Paus, Tamás Bíró
Published in: Journal of Investigative Dermatology, Issue 140/5, 2020, Page(s) 1085-1088.e6, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2019.08.456

The Phytocannabinoid (–)-Cannabidiol Operates as a Complex, Differential Modulator of Human Hair Growth: Anti-Inflammatory Submicromolar versus Hair Growth Inhibitory Micromolar Effects

Author(s): Imre L. Szabó, Erika Lisztes, Gabriella Béke, Kinga Fanni Tóth, Ralf Paus, Attila Oláh, Tamás Bíró
Published in: Journal of Investigative Dermatology, Issue 140/2, 2019, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2019.07.690

Endoplasmin Is a Hypoxia-Inducible Endoplasmic Reticulum-Derived Cargo of Extracellular Vesicles Released by Cardiac Cell Lines.

Author(s): Koncz A, Turiák L, Németh K, Lenzinger D, Bárkai T, Lőrincz P, Zelenyánszki H, Vukman KV, Buzás EI, Visnovitz T.
Published in: Membranes, 2023, ISSN 2077-0375
Publisher: Molecular Diversity Preservation International
DOI: 10.3390/membranes13040431

Nanotheranostic agents for neurodegenerative diseases

Author(s): Parasuraman Padmanabhan, Mathangi Palanivel, Ajay Kumar, Domokos Máthé, George K. Radda, Kah-Leong Lim, Balázs Gulyás
Published in: Emerging Topics in Life Sciences, Issue 4/6, 2020, Page(s) 645-675, ISSN 2397-8554
Publisher: Portland Press
DOI: 10.1042/etls20190141

Cyclooxygenase-2 Modulates Glycosaminoglycan Production in the Skin During Salt Overload

Author(s): Róbert Agócs, Domonkos Pap, Dániel Sugár, Gábor Tóth, Lilla Turiák, Zoltán Veréb, Lajos Kemény, Tivadar Tulassay, Ádám Vannay, Attila J. Szabó
Published in: Frontiers in Physiology, Issue 11, 2020, ISSN 1664-042X
Publisher: Frontiers Research Foundation
DOI: 10.3389/fphys.2020.561722

Coordinated Cut and Bypass: Replication of Interstrand Crosslink-Containing DNA

Author(s): Qiuzhen Li, Kata Dudás, Gabriella Tick, Lajos Haracska
Published in: Frontiers in Cell and Developmental Biology, Issue 9, 2021, ISSN 2296-634X
Publisher: Frontiers Media S.A.
DOI: 10.3389/fcell.2021.699966

Manifestation of Triploid Heterosis in the Root System after Crossing Diploid and Autotetraploid Energy Willow Plants.

Author(s): Dudits D, Cseri A, Török K, Vankova R, Dobrev PI, Sass L, Steinbach G, Kelemen-Valkony I, Zombori Z, Ferenc G, Ayaydin F.
Published in: Genes, 2023, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes14101929

Cardioprotective efficacy of limb remote ischemic preconditioning in rats: discrepancy between meta-analysis and a three-centre in vivo study.

Author(s): Sayour NV, Brenner GB, Makkos A, Kiss B, Kovácsházi C, Gergely TG, Aukrust SG, Tian H, Zenkl V, Gömöri K, Szabados T, Bencsik P, Heinen A, Schulz R, Baxter GF, Zuurbier CJ, Vokó Z, Ferdinandy P, Giricz Z.
Published in: Caridovascular Research, 2023, ISSN 0008-6363
Publisher: Elsevier BV
DOI: 10.1093/cvr/cvad024

IBCL-222 Parallel Testing of Liquid Biopsy (ctDNA) and Tissue Biopsy Samples Yields Higher Frequency of EZH2 Mutations in Follicular Lymphoma.

Author(s): Nagy Á, Bátai B, Gróf S, Kiss L, Balogh A, Mikala G, Király PA, Jóna Á, Demeter J, Masszi T, Masszi A, Schneider T, Bödör C.
Published in: Clin Lymphoma Myeloma Leuk., Issue 21522650, 2022, ISSN 2152-2650
Publisher: Cancer Media Group
DOI: 10.1016/s2152-2650(22)01553-1

BC-miR: Monitoring Breast Cancer-Related miRNA Profile in Blood Sera-A Prosperous Approach for Tumor Detection.

Author(s): Borsos BN, Páhi ZG, Ujfaludi Z, Sükösd F, Nikolényi A, Bankó S, Pankotai-Bodó G, Oláh-Németh O, Pankotai T.
Published in: Cells, 2022, ISSN 2073-4409
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cells11172721

Extracellular Vesicle-Based Communication May Contribute to the Co-Evolution of Cancer Stem Cells and Cancer-Associated Fibroblasts in Anti-Cancer Therapy

Author(s): Gábor Valcz, Edit I. Buzás, Anna Sebestyén, Tibor Krenács, Zoltán Szállási, Péter Igaz, Béla Molnár
Published in: Cancers, Issue 12/8, 2020, Page(s) 2324, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12082324

The Medial Septum as a Potential Target for Treating Brain Disorders Associated With Oscillopathies

Author(s): Yuichi Takeuchi, Anett J. Nagy, Lívia Barcsai, Qun Li, Masahiro Ohsawa, Kenji Mizuseki, Antal Berényi
Published in: Frontiers in Neural Circuits, Issue 15, 2021, ISSN 1662-5110
Publisher: Frontiers Research Foundation
DOI: 10.3389/fncir.2021.701080

Opportunities and challenges in studying the extracellular vesicle corona.

Author(s): Buzas EI.
Published in: Nature Cell Biology, 2022, ISSN 1465-7392
Publisher: Nature Publishing Group
DOI: 10.1038/s41556-022-00983-z

Investigating the influence of taurochenodeoxycholic acid (TCDCA) on pancreatic cancer cell behavior: An RNA sequencing approach

Author(s): Eleonóra Gál, Shahram Parvaneh, Vanda Miklós, Péter Hegyi, Lajos Kemény, Zoltán Veréb, Viktória Venglovecz
Published in: Journal of Biotechnology, Issue 391, 2024, Page(s) 20-32, ISSN 0168-1656
Publisher: Elsevier BV
DOI: 10.1016/j.jbiotec.2024.05.010

Genome-wide association study identifies susceptibility loci for acute myeloid leukemia

Author(s): Wei-Yu Lin, Sarah E. Fordham, Eric Hungate, Nicola J. Sunter, Claire Elstob, Yaobo Xu, Catherine Park, Anne Quante, Konstantin Strauch, Christian Gieger, Andrew Skol, Thahira Rahman, Lara Sucheston-Campbell, Junke Wang, Theresa Hahn, Alyssa I. Clay-Gilmour, Gail L. Jones, Helen J. Marr, Graham H. Jackson, Tobias Menne, Mathew Collin, Adam Ivey, Robert K. Hills, Alan K. Burnett, Nigel H. Russell, J
Published in: Nature Communications, Issue 12/1, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-26551-x

Two Decades of Evolution of Our Understanding of the Transient Receptor Potential Melastatin 2 (TRPM2) Cation Channel

Author(s): Andras Szollosi
Published in: Life, Issue 11/5, 2021, Page(s) 397, ISSN 2075-1729
Publisher: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/life11050397

Biocompatible poly(ethylene succinate) polyester with molecular weight dependent drug release properties.

Author(s): Abdelghafour MM, Orbán Á, Deák Á, Lamch Ł, Frank É, Nagy R, Ziegenheim S, Sipos P, Farkas E, Bari F, Janovák L.
Published in: Biomaterials, 2022, ISSN 0142-9612
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.ijpharm.2022.121653

Temporally Targeted Interactions With Pathologic Oscillations as Therapeutical Targets in Epilepsy and Beyond.

Author(s): Földi T, Lőrincz ML and Berényi
Published in: Frontiers in Neural Circuits, 2021, ISSN 1662-5110
Publisher: Frontiers Research Foundation
DOI: 10.3389/fncir.2021.784085

Molecular imaging of bacterial outer membrane vesicles based on bacterial surface display.

Author(s): Kövesdi D, Bősze S, Szabó I, Felföldi T, Oszwald E, Padmanabhan P, Gulyás BZ, Hamdani N, Máthé D, Varga Z, Szigeti K.
Published in: Scientific Reports, 2023, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-023-45628-9

Microenvironment shapes small-cell lung cancer neuroendocrine states and presents therapeutic opportunities

Author(s): Parth Desai, Nobuyuki Takahashi, Rajesh Kumar, Samantha Nichols, Justin Malin, Allison Hunt, Christopher Schultz, Yingying Cao, Desiree Tillo, Darryl Nousome, Lakshya Chauhan, Linda Sciuto, Kimberly Jordan, Vinodh Rajapakse, Mayank Tandon, Delphine Lissa, Yang Zhang, Suresh Kumar, Lorinc Pongor, Abhay Singh, Brett Schroder, Ajit Kumar Sharma, Tiangen Chang, Rasa Vilimas, Danielle Pinkiert, Chante
Published in: Cell Reports Medicine, Issue 5, 2024, Page(s) 101610, ISSN 2666-3791
Publisher: Cell Press
DOI: 10.1016/j.xcrm.2024.101610

Multiple Layers of Complexity in O-Glycosylation Illustrated With the Urinary Glycoproteome.

Author(s): Pap A, Kiraly IE, Medzihradszky KF, Darula Z.
Published in: Molecular and Cellular Proteomics, 2022, ISSN 1535-9476
Publisher: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.mcpro.2022.100439

Intracellular Ca2+ Signalling in the Pathogenesis of Acute Pancreatitis: Recent Advances and Translational Perspectives

Author(s): Petra Pallagi, Tamara Madácsy, Árpád Varga, József Maléth
Published in: International Journal of Molecular Sciences, Issue 21/11, 2020, Page(s) 4005, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21114005

MiR-128-3p as blood based liquid biopsy biomarker in childhood acute lymphoblastic leukemia.

Author(s): Rzepiel A, Horváth A, Kutszegi N, Gézsi A, Sági JC, Almási L, Egyed B, Lőrincz P, Visnovitz T, Kovács GT, Szalai C, Semsei ÁF, Erdélyi DJ.
Published in: Molecular and Cellular Probes, 2023, ISSN 0890-8508
Publisher: Academic Press
DOI: 10.1016/j.mcp.2023.101893

Dry storage of mammalian spermatozoa and cells: state-of-the-art and possible future directions

Author(s): P. Loi, D. A. Anzalone, L. Palazzese, A. Dinnyés, J. Saragusty, M. Czernik
Published in: Reproduction, Fertility and Development, Issue 33/2, 2021, Page(s) 82, ISSN 1031-3613
Publisher: Commonwealth Scientific and Industrial Research Organization Publishing
DOI: 10.1071/rd20264

TFLink: an integrated gateway to access transcription factor-target gene interactions for multiple species.

Author(s): Liska O, Bohár B, Hidas A, Korcsmáros T, Papp B, Fazekas D, Ari E.
Published in: Database, Issue 17580463, 2022, ISSN 1758-0463
Publisher: Oxford University Press
DOI: 10.1093/database/baac083

The Skin–Brain Axis: From UV and Pigmentation to Behaviour Modulation

Author(s): Anna A. Ascsillán, Lajos V. Kemény
Published in: International Journal of Molecular Sciences, Issue 25, 2024, Page(s) 6199, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms25116199

Ejection Fraction-Related Differences of Baseline Characteristics and Outcomes in Troponin-Positive Patients without Obstructive Coronary Artery Disease

Author(s): Mustafa Kacmaz, Clara Schlettert, Fabienne Kreimer, Mohammad Abumayyaleh, Ibrahim Akin, Andreas Mügge, Assem Aweimer, Nazha Hamdani, Ibrahim El-Battrawy
Published in: Journal of Clinical Medicine, Issue 13, 2024, Page(s) 2826, ISSN 2077-0383
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm13102826

Predicting immune checkpoint therapy response in three independent metastatic melanoma cohorts

Author(s): Leticia Szadai, Aron Bartha, Indira Pla Parada, Alexandra I.T. Lakatos, Dorottya M.P. Pál, Anna Sára Lengyel, Natália Pinto de Almeida, Ágnes Judit Jánosi, Fábio Nogueira, Beata Szeitz, Viktória Doma, Nicole Woldmar, Jéssica Guedes, Zsuzsanna Ujfaludi, Zoltán Gábor Pahi, Tibor Pankotai, Yonghyo Kim, Balázs Győrffy, Bo Baldetorp, Charlotte Welinder, A. Marcell Szasz, Lazaro Betancourt,
Published in: Frontiers in Oncology, Issue 14, 2024, ISSN 2234-943X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fonc.2024.1428182

Tumour Necrosis Factor Alpha-induced Protein 3 Negatively Regulates Cutibacterium acnes-induced Innate Immune Events in Epidermal Keratinocytes

Author(s): Lilla Erdei, Beáta Szilvia Bolla, Renáta Bozó, Gábor Tax, Edit Urbán, Katalin Burián, Lajos Kemény, Kornélia Szabó
Published in: Acta Dermato-Venereologica, 2021, ISSN 0001-5555
Publisher: Taylor & Francis
DOI: 10.2340/00015555-3707

Molecular characterization of immune checkpoint inhibitor-induced cardiotoxicity reveals IL-17A as a driver of cardiac dysfunction after anti-PD-1 treatment.

Author(s): Gergely TG, Kucsera D, Tóth VE, Kovács T, Sayour NV, Drobni ZD, Ruppert M, Petrovich B, Ágg B, Onódi Z, Fekete N, Pállinger É, Buzás EI, Yousif LI, Meijers WC, Radovits T, Merkely B, Ferdinandy P, Varga ZV.
Published in: British Journal of Pharmacology, Issue 00071188, 2022, ISSN 0007-1188
Publisher: Wiley-Blackwell
DOI: 10.1111/bph.15984

Two-year event-free survival prediction in DLBCL patients based on in vivo radiomics and clinical parameters,

Author(s): Zsombor Ritter, Laszlo Papp, Katalin Zámbó, Zoltan Tóth, Dániel Dezso, Dániel Sándor Veres, Domokos Máthé, Ferenc Budán, Éva Karádi, Anett Balikó, László Pajor, Árpád Szomor, Erzsébet Schmidt, Hussain Alizadeh
Published in: Hematologic Malignancies, 2022, ISSN 2234-943X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.820136

Ca2+/calmodulin-dependent protein kinase II and protein kinase G oxidation contributes to impaired sarcomeric proteins in hypertrophy model.

Author(s): Gömöri K, Herwig M, Budde H, Hassoun R, Mostafi N, Zhazykbayeva S, Sieme M, Modi S, Szabados T, Pipis J, Farkas-Morvay N, Leprán I, Ágoston G, Baczkó I, Kovács Á, Mügge A, Ferdinandy P, Görbe A, Bencsik P, Hamdani N.
Published in: ESC Heart Fail, 2022, ISSN 2055-5822
Publisher: The Heart Failure Association of the European Society of Cardiology
DOI: 10.1002/ehf2.13973

Systematic transcriptomic and phenotypic characterization of human and murine cardiac myocyte cell lines and primary cardiomyocytes reveals serious limitations and low resemblances to adult cardiac phenotype. J Mol Cell Cardiol.

Author(s): Onódi Z, Visnovitz T, Kiss B, Hambalkó S, Koncz A, Ágg B, Váradi B, Tóth VÉ, Nagy RN, Gergely TG, Gergő D, Makkos A, Pelyhe C, Varga N, Reé D, Apáti Á, Leszek P, Kovács T, Nagy N, Ferdinandy P, Buzás EI, Görbe A, Giricz Z, Varga ZV.
Published in: Journal of Molecular and Cellular Cardiology, 2021, ISSN 0022-2828
Publisher: Academic Press
DOI: 10.1016/j.yjmcc.2021.12.007

Could basement membrane alterations, resembling micro‐wounds at the dermo‐epidermal junction in psoriatic non‐lesional skin, make the skin susceptible to lesion formation?

Author(s): Renáta Bozó, Lili Borbála Flink, Nóra Belső, Barbara Gubán, Márta Széll, Lajos Kemény, Zsuzsanna Bata‐Csörgő
Published in: Experimental Dermatology, 2020, ISSN 0906-6705
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/exd.14267

Gyermekkori agydaganatok: diagnózis és terápia – komprehenzív genomikai profilozás [Childhood brain tumors: diagnosis and therapy - comprehensive genomic profiling].

Author(s): Brückner E, Bedics G, Reiniger L, Rajnai H, Jakab Z, Bödör C, Scheich B, Garami M.
Published in: Magyar Onkológia, 2023, ISSN 0025-0244
Publisher: Magyar Onkologusok Tarsasaga

Gene loss and compensatory evolution promotes the emergence of morphological novelties in budding yeast

Author(s): Farkas Z, Kovács K, Sarkadi Z, Kalapis D, Fekete G, Birtyik F, Ayaydin F, Molnár C, Horváth P, Pál C, Papp B.
Published in: Nature Ecology and Evolution, 2022, ISSN 2397-334X
Publisher: Nature Publishing Group
DOI: 10.1038/s41559-022-01730-1

Distinct miRNA Expression Signatures of Primary and Secondary Central Nervous System Lymphomas.

Author(s): Sebestyén E, Nagy Á, Marosvári D, Rajnai H, Kajtár B, Deák B, Matolcsy A, Brandner S, Storhoff J, Chen N, Bagó AG, Bödör C, Reiniger L.
Published in: The journal of molecular diagnostics, 2021, ISSN 1525-1578
Publisher: American Society for Investigative Pathology
DOI: 10.1016/j.jmoldx.2021.11.005

Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells

Author(s): Roman C. Sarott, Matthias V. Westphal, Patrick Pfaff, Claudia Korn, David A. Sykes, Thais Gazzi, Benjamin Brennecke, Kenneth Atz, Marie Weise, Yelena Mostinski, Pattarin Hompluem, Eline Koers, Tamara Miljuš, Nicolas J. Roth, Hermon Asmelash, Man C. Vong, Jacopo Piovesan, Wolfgang Guba, Arne C. Rufer, Eric A. Kusznir, Sylwia Huber, Catarina Raposo, Elisabeth A. Zirwes, Anja Osterwald, Anto Pavlovi
Published in: Journal of the American Chemical Society, Issue 142/40, 2020, Page(s) 16953-16964, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.0c05587

FTO Intronic SNP Strongly Influences Human Neck Adipocyte Browning Determined by Tissue and PPARγ Specific Regulation: A Transcriptome Analysis

Author(s): Beáta B. Tóth, Rini Arianti, Abhirup Shaw, Attila Vámos, Zoltán Veréb, Szilárd Póliska, Ferenc Győry, Zsolt Bacso, László Fésüs, Endre Kristóf
Published in: Cells, Issue 9/4, 2020, Page(s) 987, ISSN 2073-4409
Publisher: MDPI AG
DOI: 10.3390/cells9040987

A series of xanthenes inhibiting Rad6 function and Rad6-Rad18 interaction in the PCNA ubiquitination cascade.

Author(s): Fenteany G, Sharma G, Gaur P, Borics A, Wéber E, Kiss E, Haracska L.
Published in: iScience, 2022, ISSN 2589-0042
Publisher: Elsevier Inc.
DOI: 10.1016/j.isci.2022.104053

Evidence of a Myenteric Plexus Barrier and its Macrophage-Dependent Degradation during Murine Colitis: Implications in Enteric Neuroinflammation

Author(s): David Dora, Szilamer Ferenczi, Rhian Stavely, Viktoria E. Toth, Zoltan V. Varga, Tamas Kovacs, Ildiko Bodi, Ryo Hotta, Krisztina J. Kovacs, Allan M. Goldstein, Nandor Nagy
Published in: Cellular and Molecular Gastroenterology and Hepatology, 2021, ISSN 2352-345X
Publisher: Elsevier Inc.
DOI: 10.1016/j.jcmgh.2021.07.003

Development of Polymer-Encapsulated, Amine-Functionalized Zinc Ferrite Nanoparticles as MRI Contrast Agents.

Author(s): Ilosvai ÁM, Forgách L, Kovács N, Heydari F, Szigeti K, Máthé D, Kristály F, Daróczi L, Kaleta Z, Viskolcz B, Nagy M, Vanyorek L.
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242216203

Effect of hypercholesterolemia on circulating and cardiomyocyte-derived extracellular vesicles

Author(s): Csenger Kovácsházi, Szabolcs Hambalkó, Nabil V. Sayour, Tamás G. Gergely, Gábor B. Brenner, Csilla Pelyhe, Dóra Kapui, Bennet Y. Weber, Alexander L. Hültenschmidt, Éva Pállinger, Edit I. Buzás, Ádám Zolcsák, Bálint Kiss, Tamás Bozó, Csilla Csányi, Nikolett Kósa, Miklós Kellermayer, Róbert Farkas, Gellért B. Karvaly, Kieran Wynne, David Matallanas, Péter Ferdinandy, Zoltán Gi
Published in: Scientific Reports, Issue 14, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-024-62689-6

Effects of bowel cleansing on the composition of the gut microbiota in inflammatory bowel disease patients and healthy controls.

Author(s): Bacsur P, Rutka M, Asbóth A, Resál T, Szántó K, Jójárt B, Bálint A, Ari E, Ajibola W, Kintses B, Fehér T, Pigniczki D, Bor R, Fábián A, Maléth J, Szepes Z, Farkas K, Molnár T.
Published in: Therapeutic Advances in Gastroenterology, 2023, ISSN 1756-283X
Publisher: SAGE Publications
DOI: 10.1177/17562848231174298

Mechanisms of myocardial reverse remodelling and its clinical significance: A scientific statement of the ESC Working Group on Myocardial Function

Author(s): Inês Falcão‐Pires, Ana Filipa Ferreira, Fábio Trindade, Luc Bertrand, Michele Ciccarelli, Valeria Visco, Dana Dawson, Nazha Hamdani, Linda W. Van Laake, Frank Lezoualc'h, Wolfgang A. Linke, Ida G Lunde, Peter P. Rainer, Mahmoud Abdellatif, Jolanda Van der Velden, Nicola Cosentino, Alessia Paldino, Giulio Pompilio, Serena Zacchigna, Stephane Heymans, Thomas Thum, Carlo Gabriele Tocchetti
Published in: European Journal of Heart Failure, Issue 26, 2024, Page(s) 1454-1479, ISSN 1388-9842
Publisher: Elsevier BV
DOI: 10.1002/ejhf.3264

Endoplasmic Reticulum‐Plasma Membrane Contact Sites as an Organizing Principle for Compartmentalized Calcium and cAMP Signaling

Author(s): Tim Crul, József Maléth
Published in: International Journal of Molecular Sciences, Issue 22/9, 2021, Page(s) 4703, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22094703

Dual amplification strategy turns TRPM2 channels into supersensitive central heat detectors.

Author(s): Bartók Á, Csanády L.
Published in: Proceedings of the National Academy of Sciences of the United States of America, Issue 00278424, 2022, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2212378119

Deciphering of Candida parapsilosis induced immune response in Drosophila melanogaster

Author(s): Katalin Csonka, Zsolt Tasi, Viktor Vedelek, Csaba Vágvölgyi, Rita Sinka, Attila Gácser
Published in: Virulence, Issue 12/1, 2021, Page(s) 2571-2582, ISSN 2150-5594
Publisher: Landes Bioscience
DOI: 10.1080/21505594.2021.1980989

A novel BRET-Based GAP assay reveals phosphorylation-dependent regulation of the RAC-specific GTPase activating protein ARHGAP25.

Author(s): Wisniewski É, Czárán D, Kovács F, Bahurek E, Németh A, Sasvári P, Szanda G, Pettkó-Szandtner A, Klement E, Ligeti E, Csépányi-Kömi R.
Published in: Faseb Journal, Issue 08926638, 2022, ISSN 0892-6638
Publisher: Federation of American Societies for Experimental Biology
DOI: 10.1096/fj.202200689r

Case Report: Development of Diffuse Large B Cell Lymphoma a Long Time After Hairy Cell Leukemia.

Author(s): Nagy ZF, Ferenczi K, Istenes I, Eid H, Bödör C, Timár B, Demeter J.
Published in: Pathology and Oncology Research, 2022, ISSN 1532-2807
Publisher: Frontiers Media S.A.
DOI: 10.3389/pore.2022.1610338

Inflammasome Activity in the Skeletal Muscle and Heart of Rodent Models for Duchenne Muscular Dystrophy. Int J Mol Sci. 2023 May 9;24(10):8497.

Author(s): Onódi Z, Szabó PL, Kucsera D, Pokreisz P, Dostal C, Hilber K, Oudit GY, Podesser BK, Ferdinandy P, Varga ZV, Kiss A.
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24108497

Commentary on ‘Sebocyte differentiation as a new target for acne therapy: an in vivo experience’

Author(s): L. Kemény, K. Szabó
Published in: Journal of the European Academy of Dermatology and Venereology, Issue 34/8, 2020, Page(s) 1637-1638, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.16788

Rapid Evolution of Reduced Susceptibility against a Balanced Dual-Targeting Antibiotic through Stepping-Stone Mutations

Author(s): Petra Szili, Gábor Draskovits, Tamás Révész, Ferenc Bogár, Dávid Balogh, Tamás Martinek, Lejla Daruka, Réka Spohn, Bálint Márk Vásárhelyi, Márton Czikkely, Bálint Kintses, Gábor Grézal, Györgyi Ferenc, Csaba Pál, Ákos Nyerges
Published in: Antimicrobial Agents and Chemotherapy, Issue 63/9, 2019, ISSN 0066-4804
Publisher: American Society for Microbiology
DOI: 10.1128/aac.00207-19

Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes.

Author(s): Casado P, Rio-Machin A, Miettinen JJ, Bewicke-Copley F, Rouault-Pierre K, Krizsan S, Parsons A, Rajeeve V, Miraki-Moud F, Taussig DC, Bödör C, Gribben J, Heckman C, Fitzgibbon J, Cutillas PR.
Published in: Signal Transduction and Targeted Therapy, 2023, ISSN 2059-3635
Publisher: Springer Nature
DOI: 10.1038/s41392-022-01288-1

Local laboratory-run donor-derived cell-free DNA assay for rejection surveillance in heart transplantation-first six months of clinical experience.

Author(s): Teszak T, Bödör C, Hegyi L, Levay L, Nagy B, Fintha A, Merkely B, Sax B.
Published in: Clinical Transplantation, 2023, ISSN 1399-0012
Publisher: Wiley-Blavkwell Publishing Ltd.
DOI: 10.1111/ctr.15078

Co-Detection of VEGF-A and Its Regulator, microRNA-181a, May Indicate Central Nervous System Involvement in Pediatric Leukemia

Author(s): Egyed B, Horváth A, Semsei ÁF, Szalai C, Müller J, Erdélyi DJ, Kovács GT
Published in: Pathology and Oncology Research, 2022, ISSN 1219-4956
Publisher: Springer Verlag
DOI: 10.3389/pore.2022.1610096

Amino Acid Polymorphisms in the VHIID Conserved Motif of Nodulation Signaling Pathways 2 Distinctly Modulate Symbiotic Signaling and Nodule Morphogenesis in Medicago truncatula.

Author(s): Kovacs S, Fodor L, Domonkos A, Ayaydin F, Laczi K, Rákhely G and Kalo P
Published in: Frontiers in plant science, 2021, ISSN 1664-462X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fpls.2021.709857

Age-Related Inflammatory Balance Shift, Nasal Barrier Function, and Cerebro-Morphological Status in Healthy and Diseased Rodents

Author(s): Zsófia Varga-Medveczky, Noémi Kovács, Melinda E. Tóth, Miklós Sántha, Ildikó Horváth, Luca Anna Bors, Katalin Fónagy, Timea Imre, Pál Szabó, Domokos Máthé, Franciska Erdő
Published in: Frontiers in Neuroscience, Issue 15, 2021, ISSN 1662-453X
Publisher: Frontiers Media S.A.
DOI: 10.3389/fnins.2021.700729

Emerging human pulmonary dirofilariasis in Hungary: a single center experience

Author(s): Levente Kuthi, Tamás Zombori, László Tiszlavicz, Fanni Hegedűs, Szintia Almási, Bence Baráth, Mohammed Almakrami, Mohammad Jamal EJ, Nikolett Barta, Zsuzsanna Ujfaludi, Tibor Pankotai, Adrienn Hajdu, József Furák, Anita Sejben
Published in: Diagnostic Pathology, Issue 19, 2024, ISSN 1746-1596
Publisher: BioMed Central
DOI: 10.1186/s13000-024-01507-z

Bile acid- and ethanol-mediated activation of Orai1 damages pancreatic ductal secretion in acute pancreatitis.

Author(s): Pallagi P, Görög M, Papp N, Madácsy T, Varga Á, Crul T, Szabó V, Molnár M, Dudás K, Grassalkovich A, Szederkényi E, Lázár G, Venglovecz V, Hegyi P, Maléth J.
Published in: The journal of physiology A publication of the Physiological Society., 2022, ISSN 1469-7793
Publisher: The journal of physiology
DOI: 10.1113/jp282203

Hepatocyte vitamin D receptor functions as a nutrient sensor that regulates energy storage and tissue growth in zebrafish

Author(s): Scott H. Freeburg, Arkadi Shwartz, Lajos V. Kemény, Colton J. Smith, Olivia Weeks, Bess M. Miller, Nadia PenkoffLidbeck, David E. Fisher, Kimberley J. Evason, Wolfram Goessling
Published in: Cell Reports, Issue 43, 2024, Page(s) 114393, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2024.114393

Saxagliptin Cardiotoxicity in Chronic Heart Failure: The Role of DPP4 in the Regulation of Neuropeptide Tone.

Author(s): Vörös I, Onódi Z, Tóth VÉ, Gergely TG, Sághy É, Görbe A, Kemény Á, Leszek P, Helyes Z, Ferdinandy P, Varga ZV.
Published in: Biomedicines, 2022, ISSN 2227-9059
Publisher: MDPI AG
DOI: 10.3390/biomedicines10071573

BC-Monitor: Towards a Routinely Accessible Circulating Tumor DNA-Based Tool for Real-Time Monitoring Breast Cancer Progression and Treatment Effectiveness

Author(s): Katalin Priskin, Sára Pólya, Lajos Pintér, Gábor Jaksa, Bernadett Csányi, Márton Zsolt Enyedi, Eszter Sági-Zsigmond, Farkas Sükösd, Orsolya Oláh-Németh, Gyöngyi Kelemen, Alíz Nikolényi, Gabriella Uhercsák, Dóra Sántha, Ágnes Dobi, Éva Szilágyi, Erzsébet Valicsek, László Tordai, Rozália Tóth, Zsuzsanna Kahán, Lajos Haracska
Published in: Cancers, Issue 13/14, 2021, Page(s) 3489, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13143489

Impacts of gene variants on drug effects-the foundation of genotype-guided pharmacologic therapy for long QT syndrome and short QT syndrome

Author(s): Zhihan Zhao, Xiaobiao Zang, Kerun Niu, Weifeng Song, Xianqing Wang, Andreas Mügge, Assem Aweimer, Nazha Hamdani, Xiaobo Zhou, Yonghui Zhao, Ibrahim Akin, Ibrahim El-Battrawy
Published in: eBioMedicine, Issue 103, 2024, Page(s) 105108, ISSN 2352-3964
Publisher: Elsevier BV
DOI: 10.1016/j.ebiom.2024.105108

GATA2 deficiency and MDS/AML: Experimental strategies for disease modelling and future therapeutic prospects.

Author(s): Kotmayer L, Romero-Moya D, Marin-Bejar O, Kozyra E, Català A, Bigas A, Wlodarski MW, Bödör C, Giorgetti A.
Published in: British Journal of Haematology, 2022, ISSN 0007-1048
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/bjh.18330

Spreading depolarization causes reperfusion failure after cerebral ischemia.

Author(s): Törteli A, Tóth R, Berger S, Samardzic S, Bari F, Menyhárt Á, Farkas E.
Published in: Journal of Cerebral Blood Flow and Metabolism, 2023, ISSN 0271-678X
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1177/0271678x231153745

Characterization of antibiotic resistomes by reprogrammed bacteriophage-enabled functional metagenomics in clinical strains.

Author(s): Apjok G, Számel M, Christodoulou C, Seregi V, Vásárhelyi BM, Stirling T, Eszenyi B, Sári T, Vidovics F, Nagrand E, Kovács D, Szili P, Lantos II, Méhi O, Jangir PK, Herczeg R, Gálik B, Urbán P, Gyenesei A, Draskovits G, Nyerges Á, Fekete G, Bodai L, Zsindely N, Dénes B, Yosef I, Qimron U, Papp B, Pál C, Kintses B.
Published in: Nature Microbiology, 2023, ISSN 2058-5276
Publisher: Nature Publishing Group
DOI: 10.1038/s41564-023-01320-2

Symphony of surprises: Unveiling organ interactions in Takotsubo Syndrome

Author(s): Daniel Strohleit, Assem Aweimer, Ibrahim Akin, Nazha Hamdani, Ibrahim El-Battrawy
Published in: International Journal of Cardiology, Issue 408, 2024, Page(s) 132148, ISSN 0167-5273
Publisher: Elsevier BV
DOI: 10.1016/j.ijcard.2024.132148

Bile accelerates carcinogenic processes in pancreatic ductal adenocarcinoma cells through the overexpression of MUC4

Author(s): Eleonóra Gál, Zoltán Veréb, Lajos Kemény, Dávid Rakk, András Szekeres, Eszter Becskeházi, László Tiszlavicz, Tamás Takács, László Czakó, Péter Hegyi, Viktória Venglovecz
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-79181-6

The loss of DNA polymerase epsilon accessory subunits POLE3–POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

Author(s): Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, Eva Pinto Jurado, Siham Zentout, Alexandra Mihuţ, Anna Georgina Kopasz, Mihály Mérey, Rebecca Smith, Abhishek Bharadwaj Sharma, Nicholas D Lakin, Andrew James Bowman, Lajos Haracska, Sébastien Huet, Gyula Timinszky
Published in: Nucleic Acids Research, Issue 52, 2024, Page(s) 6994-7011, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkae439

Werner helicase interacting protein 1 contributes to G-quadruplex processing in human cells

Author(s): Lili Hegedus, Agnes Toth, Gabor M. Harami, Janos Palinkas, Nargis Karatayeva, Eniko Sajben-Nagy, Szabolcs Bene, Sara Afzali Jaktajdinani, Mihaly Kovacs, Szilvia Juhasz, Peter Burkovics
Published in: Scientific Reports, Issue 14, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-024-66425-y

Chloroplast phosphate transporter CrPHT4-7 regulates phosphate homeostasis and photosynthesis in Chlamydomonas.

Author(s): Tóth D, Kuntam S, Ferenczi Á, Vidal-Meireles A, Kovács L, Wang L, Sarkadi Z, Migh E, Szentmihályi K, Tengölics R, Neupert J, Bock R, Jonikas MC, Molnar A, Tóth SZ.
Published in: Plant Phsyiology, 2023, ISSN 0032-0889
Publisher: American Society of Plant Biologists
DOI: 10.1093/plphys/kiad607

Insights into the Structure of Comirnaty Covid-19 Vaccine: A Theory on Soft, Partially Bilayer-Covered Nanoparticles with Hydrogen Bond-Stabilized mRNA-Lipid Complexes.

Author(s): Szebeni J, Kiss B, Bozó T, Turjeman K, Levi-Kalisman Y, Barenholz Y, Kellermayer M.
Published in: ACS Nano, 2023, ISSN 1936-086X
Publisher: American Chemical Society
DOI: 10.1021/acsnano.2c11904

Case report: Complete and durable response to larotrectinib (TRK inhibitor) in an infant diagnosed with angiosarcoma harbouring a KHDRBS1-NTRK3 fusion gene.

Author(s): Cervi C, Sápi Z, Bedics G, Zajta E, Hegyi L, Pápay J, Dezső K, Varga E, Mudra K, Bödör C, Csóka M.
Published in: Frontiers in Oncology, 2023, ISSN 2234-943X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fonc.2023.999810

Impact of Experimental Conditions on Extracellular Vesicles' Proteome: A Comparative Study.

Author(s): Böröczky T, Dobra G, Bukva M, Gyukity-Sebestyén E, Hunyadi-Gulyás É, Darula Z, Horváth P, Buzás K, Harmati M.
Published in: Life, 2023, ISSN 2075-1729
Publisher: MDPI
DOI: 10.3390/life13010206

CRISPR/Cas9 Mutagenesis through Introducing a Nanoparticle Complex Made of a Cationic Polymer and Nucleic Acids into Maize Protoplasts.

Author(s): Nagy B, Öktem A, Ferenc G, Ungor D, Kalac A, Kelemen-Valkony I, Fodor E, Nagy I, Dudits D, Ayaydin F.
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242216137

Blood-brain barrier dysfunction in L-ornithine induced acute pancreatitis in rats and the direct effect of L-ornithine on cultured brain endothelial cells.

Author(s): Walter FR, Harazin A, Tóth AE, Veszelka S, Santa-Maria AR, Barna L, Kincses A, Biczó G, Balla Z, Kui B, Maléth J, Cervenak L, Tubak V, Kittel Á, Rakonczay Z Jr, Deli MA
Published in: Fluid and Barrier of the cNS, 2022, ISSN 2045-8118
Publisher: BioMed Central
DOI: 10.1186/s12987-022-00308-0

Landscape of BCL2 Resistance Mutations in a Real-World Cohort of Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia Treated with Venetoclax.

Author(s): Kotmayer L, László T, Mikala G, Kiss R, Lévay L, Hegyi LL, Gróf S, Nagy T, Barna G, Farkas P, Weisinger J, Nagy Z, Balogh A, Masszi T, Demeter J, Sulák A, Kohl Z, Alizadeh H, Egyed M, Pettendi P, Gergely L, Plander M, Pauker Z, Masszi A, Matolcsy A, Szász R, Bödör C, Alpár D.
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24065802

Nanofiber formation as a promising technology for preservation and easy storage of extracellular vesicles.

Author(s): Németh K, Kazsoki A, Visnovitz T, Pinke B, Mészáros L, Buzás EI, Zelkó R.
Published in: Scientific Reports, 2022, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-25916-6

Proteome-wide landscape of solubility limits in a bacterial cell.

Author(s): Györkei Á, Daruka L, Balogh D, Őszi E, Magyar Z, Szappanos B, Fekete G, Fuxreiter M, Horváth P, Pál C, Kintses B, Papp B.
Published in: Scientific reports, 2022, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-10427-1

Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling.

Author(s): Schoger E, Bleckwedel F, Germena G, Rocha C, Tucholla P, Sobitov I, Möbius W, Sitte M, Lenz C, Samak M, Hinkel R, Varga ZV, Giricz Z, Salinas G, Gross JC, Zelarayán LC.
Published in: Communications Biology, 2023, ISSN 2399-3642
Publisher: Springer Nature
DOI: 10.1038/s42003-022-04402-9

Epigenome profiling reveals aberrant DNA methylation signature in GATA2 deficiency.

Author(s): Marin-Bejar O, Romero-Moya D, Rodriguez-Ubreva J, Distefano M, Lessi F, Aretini P, Liquori A, Castaño J, Kozyra E, Kotmayer L, Bueno C, Cervera J, Rodriguez-Gallego JC, Nomdedeu JF, Murillo-Sanjuán L, De Heredia CD, Pérez-Martinez A, López-Cadenas F, Martínez-Laperche C, Dorado-Herrero N, Marco FM, Prósper F, Menendez P, Valcárcel D, Ballestar E, Bödör C, Bigas A, Catalá A, Wlodarski MW,
Published in: Acta Haematologica, 2023, ISSN 0001-5792
Publisher: S. Karger AG
DOI: 10.3324/haematol.2022.282305

PCSK9 in Myocardial Infarction and Cardioprotection: Importance of Lipid Metabolism and Inflammation

Author(s): Ioanna Andreadou, Maria Tsoumani, Gemma Vilahur, Ignatios Ikonomidis, Lina Badimon, Zoltán V. Varga, Péter Ferdinandy, Rainer Schulz
Published in: Frontiers in Physiology, Issue 11, 2020, ISSN 1664-042X
Publisher: Frontiers Research Foundation
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Suppression of Metastatic Melanoma Growth in Lung by Modulated Electro-Hyperthermia Monitored by a Minimally Invasive Heat Stress Testing Approach in Mice

Author(s): Mbuotidem Jeremiah Thomas, Enikő Major, Anett Benedek, Ildikó Horváth, Domokos Máthé, Ralf Bergmann, Attila Marcell Szász, Tibor Krenács, Zoltán Benyó
Published in: Cancers, Issue 12/12, 2020, Page(s) 3872, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
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Differential impact of exportin-1-mediated nuclear export of RNAs on the RNA content of extracellular vesicle subpopulations

Author(s): Pálóczi K, Buzas EI, Falus A.
Published in: Biologia Futura, 2023, ISSN 2676-8607
Publisher: Akaedimai Kiado
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Small extracellular vesicles convey the stress-induced adaptive responses of melanoma cells

Author(s): Maria Harmati, Edina Gyukity-Sebestyen, Gabriella Dobra, Laszlo Janovak, Imre Dekany, Okay Saydam, Eva Hunyadi-Gulyas, Istvan Nagy, Attila Farkas, Tibor Pankotai, Zsuzsanna Ujfaludi, Peter Horvath, Filippo Piccinini, Maria Kovacs, Tamas Biro, Krisztina Buzas
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
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Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions.

Author(s): Császár E, Lénárt N, Cserép Cs, Környei Zs, Fekete R, Pósfai B, Balázsfi D, Hangya B, D. Schwarz A, Szabadits E, Szöllősi D, Szigeti K, Máthé D, L.Wset B, Sviatskó K, Brás A R, Mariani J-C, Kliever A, Lenkei Zs, Hricisák L, Benyó Z, Baranyi M, Sperlágh B, Menyhárt Á, Farkas E, Dénes Á.
Published in: Journal of experimental medicine, 2022, ISSN 0022-1007
Publisher: Rockefeller University Press
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Neural stem cells traffic functional mitochondria via extracellular vesicles

Author(s): Luca Peruzzotti-Jametti, Joshua D. Bernstock, Cory M. Willis, Giulia Manferrari, Rebecca Rogall, Erika Fernandez-Vizarra, James C. Williamson, Alice Braga, Aletta van den Bosch, Tommaso Leonardi, Grzegorz Krzak, Ágnes Kittel, Cristiane Benincá, Nunzio Vicario, Sisareuth Tan, Carlos Bastos, Iacopo Bicci, Nunzio Iraci, Jayden A. Smith, Ben Peacock, Karin H. Muller, Paul J. Lehner, Edit Iren Buzas,
Published in: PLOS Biology, Issue 19/4, 2021, Page(s) e3001166, ISSN 1545-7885
Publisher: Public Library of Science
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Platelet-Rich Plasma in Chronic Wound Management: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.

Author(s): Meznerics FA, Fehérvári P, Dembrovszky F, Kovács KD, Kemény LV, Csupor D, Hegyi P, Bánvölgyi A.
Published in: Journal of Clinical Medicine, 2022, ISSN 2077-0383
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm11247532

Editorial: Cardiovascular sequelae of chemotherapy and radiotherapy in cancer survivors: current evidence and perspectives. Front Cardiovasc Med. 2023 Jun 20;10:1230862.

Author(s): Felici T, Skinner R, Ferdinandy P, Varga ZV, Lombardo A, Camilli M.
Published in: Frontiers in Cardiovascular Medicine, 2023, ISSN 2297-055X
Publisher: Frontiers Media S.A.
DOI: 10.3389/fcvm.2023.1230862

Psoriasis-Associated Inflammatory Conditions Induce IL-23 mRNA Expression in Normal Human Epidermal Keratinocytes.

Author(s): Kelemen E, Ádám É, Sági SM, Göblös A, Kemény L, Bata-Csörgő Z, Széll M, Danis J.
Published in: MDPI- Journal of molecular sciences, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
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Bedics G, Kotmayer L, Zajta E, Hegyi LL, Brückner EÁ, Rajnai H, Reiniger L, Bödör C, Garami M, Scheich B.

Author(s): Germline MUTYH mutations and high-grade gliomas: novel evidence for a potential association
Published in: Genes Chromosomes and Cancer, 2022, ISSN 1045-2257
Publisher: Wiley-Liss Inc
DOI: 10.1002/gcc.23054

Topography, Spike Dynamics, and Nanomechanics of Individual Native SARS-CoV-2 Virions

Author(s): Bálint Kiss, Zoltán Kis, Bernadett Pályi, Miklós S. Z. Kellermayer
Published in: Nano Letters, 2021, ISSN 1530-6984
Publisher: American Chemical Society
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Results of a systematic review and meta-analysis of early studies on ivermectin in SARS-CoV-2 infection. Geroscience.

Author(s): Ragó Z, Tóth B, Szalenko-Tőkés Á, Bella Z, Dembrovszky F, Farkas N, Kiss S, Hegyi P, Matuz M, Tóth N, Hegedüs I, Máthé D, Csupor D.
Published in: Geroscience, 2023, ISSN 2509-2715
Publisher: Springer International Publishing AG
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The Medicago truncatula nodule-specific cysteine-rich peptides, NCR343 and NCR-new35 are required for the maintenance of rhizobia in nitrogen-fixing nodules.

Author(s): Horváth B, Güngör B, Tóth M, Domonkos Á, Ayaydin F, Saifi F, Chen Y, Biró JB, Bourge M, Szabó Z, Tóth Z, Chen R, Kaló P.
Published in: New Phytologist, 2023, ISSN 1469-8137
Publisher: Wiley-Blackwell Publishing Ltd
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TRPM2 - An adjustable thermostat.

Author(s): Bartók Á, Csanády L.
Published in: Cell Calcium, 2024, ISSN 1532-1991
Publisher: Elsevier Ltd.
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STABILON, a Novel Sequence Motif That Enhances the Expression and Accumulation of Intracellular and Secreted Proteins.

Author(s): Rethi-Nagy Z, Abraham E, Udvardy K, Klement E, Darula Z, Pal M, Katona RL, Tubak V, Pali T, Kota Z, Sinka R, Udvardy A, Lipinszki Z.
Published in: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
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Human pancreatic ductal organoids with controlled polarity provide a novel ex vivo tool to study epithelial cell physiology.

Author(s): Varga Á, Madácsy T, Görög M, Kiss A, Susánszki P, Szabó V, Jójárt B, Dudás K, Farkas G Jr, Szederkényi E, Lázár G, Farkas A, Ayaydin F, Pallagi P, Maléth J.
Published in: Cellular and Molecular Life Sciences, 2023, ISSN 1420-682X
Publisher: Birkhauser Verlag
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Closed-loop stimulation of the medial septum terminates epileptic seizures

Author(s): Yuichi Takeuchi, Márk Harangozó, Lizeth Pedraza, Tamás Földi, Gábor Kozák, Qun Li, Antal Berényi
Published in: Brain, 2021, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awaa450

The Small Heat Shock Protein, HSPB1, Interacts with and Modulates the Physical Structure of Membranes

Author(s): Csoboz B, Gombos I, Kóta Z, Dukic B, Klement É, Varga-Zsíros V, Lipinszki Z, Páli T, Vígh L, Török Z.
Published in: International Journal of Molecular Sciences, Issue 14220067, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
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Improvement of lidocaine skin permeation by using passive and active enhancer methods

Author(s): Feria Hasanpour, Mária Budai-Szűcs, Anita Kovács, Rita Ambrus, Orsolya Jójárt-Laczkovich, Martin Cseh, Zsolt Geretovszky, Ferhan Ayaydin, Szilvia Berkó
Published in: International Journal of Pharmaceutics, Issue 660, 2024, Page(s) 124377, ISSN 0378-5173
Publisher: Elsevier BV
DOI: 10.1016/j.ijpharm.2024.124377

The 3M Concept: Biomedical Translational Imaging from Molecules to Mouse to Man

Author(s): Domokos Máthé, Bálint Kiss, Bernadett Pályi, Zoltán Kis, László Forgách, Nikolett Hegedűs, Zoltán Varga, Krisztián Szigeti, Kinga Karlinger, Miklós S Z Kellermayer
Published in: The EuroBiotech Journal, Issue 5/3, 2021, Page(s) 155-160, ISSN 2564-615X
Publisher: European Biotechnology Thematic Network Association
DOI: 10.2478/ebtj-2021-0024

An implanted device enables in vivo monitoring of extracellular vesicle‐mediated spread of pro‐inflammatory mast cell response in mice

Author(s): Krisztina V. Vukman, Andrea Ferencz, Daniella Fehér, Krisztina Juhos, Péter Lőrincz, Tamás Visnovitz, Anna Koncz, Krisztina Pálóczi, Gábor Seregélyes, András Försönits, Delaram Khamari, Alicia Galinsoga, László Drahos, Edit I. Buzás
Published in: Journal of Extracellular Vesicles, 2021, Page(s) 10:e12023, ISSN 2001-3078
Publisher: Taylor and Francis Ltd.
DOI: 10.1002/jev2.12023

Low-burden TP53 mutations represent frequent genetic events in CLL with an increased risk for treatment initiation.

Author(s): László T, Kotmayer L, Fésüs V, Hegyi L, Gróf S, Nagy Á, Kajtár B, Balogh A, Weisinger J, Masszi T, Nagy Z, Farkas P, Demeter J, Istenes I, Szász R, Gergely L, Sulák A, Borbényi Z, Lévai D, Schneider T, Pettendi P, Bodai E, Szerafin L, Rejtő L, Bátai Á, Dömötör MÁ, Sánta H, Plander M, Szendrei T, Hamed A, Lázár Z, Pauker Z, Radványi G, Kiss A, Körösmezey G, Jakucs J, Dombi P
Published in: Journal of Pathology: Clinical Research, 2024, ISSN 2056-4538
Publisher: Wiley-Blackwell Publishing Ltd
DOI: 10.1002/cjp2.351

Decreased Plasma Level of Cytokeratin 20 (KRT20) Is Indicative of the Emergence and Severity of Acute GvHD Irrespective to the Type of Organ Involvement.

Author(s): Lupsa N, Szegedi Á, Gézsi A, Vuncs Z, Masszi T, Mikala G, Reményi P, Deola S, Lakshmanan AP, Terranegra A, Buzás EI, Pós Z.
Published in: Biomedicines, 2022, ISSN 2227-9059
Publisher: MDPI AG
DOI: 10.3390/biomedicines10030519

3D culturing of human pluripotent stem cells-derived endothelial cells for vascular regeneration

Author(s): Edit Gara, Eleonora Zucchelli, Annamária Nemes, Zoltán Jakus, Kitti Ajtay, Éva Kemecsei, Gábor Kiszler, Nikolett Hegedűs, Krisztián Szigeti, Iván Földes, Kristóf Árvai, János Kósa, Kraszimir Kolev, Erzsébet Komorowicz, Parasuraman Padmanabhan, Pál Maurovich-Horvat, Edit Dósa, György Várady, Miklós Pólos, István Hartyánszky, Sian E. Harding, Béla Merkely, Domokos Máthé, Gáb
Published in: Theranostics, 2022, ISSN 1838-7640
Publisher: Ivyspring International Publisher
DOI: 10.7150/thno.69938

Single-Cell Sequencing: Biological Insight and Potential Clinical Implications in Pediatric Leukemia

Author(s): Donát Alpár, Bálint Egyed, Csaba Bödör, Gábor T. Kovács
Published in: Cancers, Issue 13/22, 2021, Page(s) 5658, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13225658

Protein Kinase D3 (PKD3) Requires Hsp90 for Stability and Promotion of Prostate Cancer Cell Migration.

Author(s): Varga A, Nguyen MT, Pénzes K, Bátai B, Gyulavári P, Gurbi B, Murányi J, Csermely P, Csala M, Vántus T, Sőti C.
Published in: Cells, 2023, ISSN 2073-4409
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cells12020212

The RUNX1 Database (RUNX1db): establishment of an expert curated RUNX1 registry and genomics database as a public resource for familial platelet disorder with myeloid malignancy

Author(s): Claire C. Homan, Sarah L. King-Smith, David M. Lawrence, Peer Arts, Jinghua Feng, James Andrews, Mark Armstrong, Thuong Ha, Julia Dobbins, Michael W. Drazer, Kai Yu, Csaba Bödör, Alan Cantor, Mario Cazzola, Erin Degelman, Courtney D. DiNardo, Nicolas Duployez, Remi Favier, Stefan Fröhling, Jude Fitzgibbon, Jeffery M. Klco, Alwin Krämer, Mineo Kurokawa, Joanne Lee, Luca Malcovati, Neil V. Morga
Published in: Haematologica, 2020, ISSN 0390-6078
Publisher: Ferrata Storti Foundation
DOI: 10.3324/haematol.2021.278762

Formation of a protein corona on the surface of extracellular vesicles in blood plasma

Author(s): Eszter Á. Tóth, Lilla Turiák, Tamás Visnovitz, Csaba Cserép, Anett Mázló, Barbara W. Sódar, András I. Försönits, Gábor Petővári, Anna Sebestyén, Zsolt Komlósi, László Drahos, Ágnes Kittel, György Nagy, Attila Bácsi, Ádám Dénes, Yong Song Gho, Katalin É. Szabó‐Taylor, Edit I. Buzás
Published in: Journal of Extracellular Vesicles, Issue 10/11, 2021, ISSN 2001-3078
Publisher: Taylor and Francis Ltd.
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Rational design of balanced dual-targeting antibiotics with limited resistance

Author(s): Akos Nyerges, Tihomir Tomašič, Martina Durcik, Tamas Revesz, Petra Szili, Gabor Draskovits, Ferenc Bogar, Žiga Skok, Nace Zidar, Janez Ilaš, Anamarija Zega, Danijel Kikelj, Lejla Daruka, Balint Kintses, Balint Vasarhelyi, Imre Foldesi, Diána Kata, Martin Welin, Raymond Kimbung, Dorota Focht, Lucija Peterlin Mašič, Csaba Pal
Published in: PLOS Biology, Issue 18/10, 2020, Page(s) e3000819, ISSN 1545-7885
Publisher: Public Library of Science
DOI: 10.1371/journal.pbio.3000819

A Randomized Controlled Trial with a Medical Device Containing Sodium Hyaluronate and Nicotinic Acid to Increase the Efficacy of Ultraviolet Phototherapy in Psoriasis

Author(s): Balázs Bende, Róbert Kui, Annamária Németh, Mariann Borsos, Zoltán Tóbiás, Gábor Erős, Lajos Kemény, Eszter Baltás
Published in: Dermatology and Therapy, Issue 10/4, 2020, Page(s) 651-662, ISSN 2190-9172
Publisher: Springer Verlag
DOI: 10.1007/s13555-020-00385-9

Psychological Effects of the COVID-19 Pandemic on Hungarian Adults

Author(s): Csanád Szabó, Judit Pukánszky, Lajos Kemény
Published in: International Journal of Environmental Research and Public Health, Issue 17/24, 2020, Page(s) 9565, ISSN 1660-4601
Publisher: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/ijerph17249565

A Comprehensive Evaluation of the Performance of Prediction Algorithms on Clinically Relevant Missense Variants.

Author(s): Qorri E, Takács B, Gráf A, Enyedi MZ, Pintér L, Kiss E, Haracska L.
Published in: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23147946

A High-Throughput Clinical Laboratory Methodology for the Therapeutic Monitoring of Ibrutinib and Dihydrodiol Ibrutinib.

Author(s): Karvaly GB, Vincze I, Balogh A, Köllő Z, Bödör C, Vásárhelyi B.
Published in: Molecules, 2022, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules27154766

Routine molecular applications and recent advances in breast cancer diagnostics. J Biotechnol.

Author(s): Pankotai-Bodó G, Oláh-Németh O, Sükösd F, Pankotai T.
Published in: Hournal of Biotechnology, 2024, ISSN 0168-1656
Publisher: Elsevier BV
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Somatostatin and Its Receptors in Myocardial Ischemia/Reperfusion Injury and Cardioprotection

Author(s): Imre Vörös, Éva Sághy, Krisztina Pohóczky, András Makkos, Zsófia Onódi, Gábor B. Brenner, Tamás Baranyai, Bence Ágg, Barnabás Váradi, Ágnes Kemény, Przemyslaw Leszek, Anikó Görbe, Zoltán V. Varga, Zoltán Giricz, Rainer Schulz, Zsuzsanna Helyes, Péter Ferdinandy
Published in: Frontiers in Pharmacology, Issue 12, 2021, ISSN 1663-9812
Publisher: Frontiers Media S.A.
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SignaLink3: a multi-layered resource to uncover tissue-specific signaling networks

Author(s): Luca Csabai, Dávid Fazekas, Tamás Kadlecsik, Máté Szalay-Bekő, Balázs Bohár, Matthew Madgwick, Dezső Módos, Márton Ölbei, Lejla Gul, Padhmanand Sudhakar, János Kubisch, Oyebode James Oyeyemi, Orsolya Liska, Eszter Ari, Bernadette Hotzi, Viktor A Billes, Eszter Molnár, László Földvári-Nagy, Kitti Csályi, Amanda Demeter, Nóra Pápai, Mihály Koltai, Máté Varga, Katalin Lenti, Il
Published in: Nucleic Acids Research, 2021, ISSN 0305-1048
Publisher: Oxford University Press
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Toward better drug development: Three-dimensional bioprinting in toxicological research.

Author(s): Szűcs D, Fekete Z, Guba M, Kemény L, Jemnitz K, Kis E, Veréb Z.
Published in: International Journal of Bioprinting, 2023, ISSN 2424-8002
Publisher: Whoice Publishing Pte Ltd.
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Inflammasome activation in end-stage heart failure-associated atrial fibrillation.

Author(s): Kugler S, Onódi Z, Ruppert M, Sayour AA, Oláh A, Benke K, Ferdinandy P, Merkely B, Radovits T, Varga ZV.
Published in: ESC heart failure, 2022, ISSN 2055-5822
Publisher: The Heart Failure Association of the European Society of Cardiology
DOI: 10.1002/ehf2.13972

Antibiotic combinations reduce Staphylococcus aureus clearance.

Author(s): Lázár V, Snitser O, Barkan D, Kishony R.
Published in: Nature, Issue 00280836, 2022, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-022-05260-5

Plasticity and stereotypic rewiring of the transcriptome upon bacterial evolution of antibiotic resistance.

Author(s): Grézal G, Spohn R, Méhi O, Dunai A, Lázár V, Bálint B, Nagy I, Pál C, Papp B.
Published in: Molecular Biology and Evolution, 2023, ISSN 0737-4038
Publisher: Oxford University Press
DOI: 10.1093/molbev/msad020

Proteomic Changes of Osteoclast Differentiation in Rheumatoid and Psoriatic Arthritis Reveal Functional Differences.

Author(s): Kovács OT, Tóth E, Ozohanics O, Soltész-Katona E, Marton N, Buzás EI, Hunyady L, Drahos L, Turu G, Nagy G.
Published in: Frontiers in Immunology, 2022, ISSN 1664-3224
Publisher: Frontiers Media S.A.
DOI: 10.3389/fimmu.2022.892970

YB-1 Is a Novel Target for the Inhibition of α-Adrenergic-Induced Hypertrophy

Author(s): Heger J, Partsch S, Harjung C, Varga ZV, Baranyai T, Weiß J, Kremer L, Locquet F, Leszek P, Ágg B, Benczik B, Ferdinandy P, Schulz R, Euler G
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms25010401

Prolonged activity of the transposase helper may raise safety concerns during DNA transposon-based gene therapy.

Author(s): Imre G, Takács B, Czipa E, Drubi AB, Jaksa G, Latinovics D, Nagy A, Karkas R, Hudoba L, Vásárhelyi BM, Pankotai-Bodó G, Blastyák A, Hegedűs Z, Germán P, Bálint B, Ahmed Abdullah KS, Kopasz AG, Kovács A, Nagy LG, Sükösd F, Pintér L, Rülicke T, Barta E, Nagy I, Haracska L, Mátés L.
Published in: Molecular Therapy - Methods and Clinical Development, 2023, ISSN 2329-0501
Publisher: Cell Press
DOI: 10.1016/j.omtm.2023.03.003

The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ

Author(s): Xuexin Li, Ivó Hernandez, Seda Koyuncu, Balázs Kis, Maria Häggblad, Louise Lidemalm, Anna A. Abbas, Sramkó Bendegúz, Anikó Göblös, Lars Brautigam, Jose J. Lucas, Jordi Carreras-Puigvert, Daniela Hühn, Karolina Pircs, David Vilchez, Oscar Fernandez-Capetillo
Published in: eBioMedicine, Issue 103, 2024, Page(s) 105124, ISSN 2352-3964
Publisher: Elsevier BV
DOI: 10.1016/j.ebiom.2024.105124

Quantitative dSTORM superresolution microscopay. AKJ Journals.

Author(s): Tibor Novák, Dániel Varga, Péter Bíró, Bálint Barna H. Kovács, Hajnalka Majoros, Tibor Pankotai, Szilárd Szikora.
Published in: AKJournals, 2022, ISSN 2062-8633
Publisher: AKJournals
DOI: 10.1556/2051.2022.00093

Male and Female Animals Respond Differently to High-Fat Diet and Regular Exercise Training in a Mouse Model of Hyperlipidemia

Author(s): Melinda E. Tóth, Brigitta Dukay, Mária Péter, Gábor Balogh, Gergő Szűcs, Ágnes Zvara, Gábor J. Szebeni, Petra Hajdu, Márta Sárközy, László G. Puskás, Zsolt Török, Tamás Csont, László Vígh, Miklós Sántha
Published in: International Journal of Molecular Sciences, Issue 22/8, 2021, Page(s) 4198, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22084198

The Effect of Molecular Weight on the Solubility Properties of Biocompatible Poly(ethylene succinate) Polyester

Author(s): Mohamed M. Abdelghafour, Ágoston Orbán, Ágota Deák, Łukasz Lamch, Éva Frank, Roland Nagy, Adél Ádám, Pál Sipos, Eszter Farkas, Ferenc Bari, László Janovák
Published in: Polymers, Issue 13/16, 2021, Page(s) 2725, ISSN 2073-4360
Publisher: MDPI AG
DOI: 10.3390/polym13162725

Functional Anatomical Changes in Ulcerative Colitis Patients Determine Their Gut Microbiota Composition and Consequently the Possible Treatment Outcome

Author(s): Anita Bálint, Klaudia Farkas, Orsolya Méhi, Bálint Kintses, Bálint Márk Vásárhelyi, Eszter Ari, Csaba Pál, Tamara Madácsy, József Maléth, Kata Judit Szántó, István Nagy, Mariann Rutka, Péter Bacsur, Diána Szűcs, Zoltán Szepes, Ferenc Nagy, Anna Fábián, Renáta Bor, Ágnes Milassin, Tamás Molnár
Published in: Pharmaceuticals, Issue 13/11, 2020, Page(s) 346, ISSN 1424-8247
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ph13110346

Cutibacterium acnes regulates the epidermal barrier properties of HPV-KER human immortalized keratinocyte cultures

Author(s): Beáta Szilvia Bolla, Lilla Erdei, Edit Urbán, Katalin Burián, Lajos Kemény, Kornélia Szabó
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-69677-6

New targets and indications for probenecid.

Author(s): Onódi Z, Koch S, Rubinstein J, Ferdinandy P, Varga ZV.
Published in: British Journal of Pharmacology, 2022, ISSN 0007-1188
Publisher: Wiley-Blackwell
DOI: 10.1111/bph.16001

Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe.

Author(s): Gazzi T, Brennecke B, Atz K, Korn C, Sykes D, Forn-Cuni G, Pfaff P, Sarott RC, Westphal MV, Mostinski Y, Mach L, Wasinska-Kalwa M, Weise M, Hoare BL, Miljuš T, Mexi M, Roth N, Koers EJ, Guba W, Alker A, Rufer AC, Kusznir EA, Huber S, Raposo C, Zirwes EA, Osterwald A, Pavlovic A, Moes S, Beck J, Nettekoven M, Benito-Cuesta I, Grande T, Drawnel F, Widmer G, Holzer D, van der Wel T, Mandhair H, Hone
Published in: Chemical Science, 2022, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1sc06659e

ING1 inhibits Twist1 expression to block EMT and is antagonized by the HDAC inhibitor vorinostat.

Author(s): Yang Y, Ma B, Djamshidi M, Zhang Q, Sarkar A, Chanda A, Tran U, Soh J, Sandall C, Chen HM, MacDonald JA, Bonni S, Sensen CW, Zheng J, Riabowol K.
Published in: European Journal of Cell Biology, 2023, ISSN 1618-1298
Publisher: Urban und Fischer Verlag GmbH und Co. KG
DOI: 10.1016/j.ejcb.2023.151341

Grafted human induced pluripotent stem cells improve the outcome of spinal cord injury: modulation of the lesion microenvironment

Author(s): Tamás Bellák, Zoltán Fekécs, Dénes Török, Zsuzsanna Táncos, Csilla Nemes, Zsófia Tézsla, László Gál, Suchitra Polgári, Julianna Kobolák, András Dinnyés, Antal Nógrádi, Krisztián Pajer
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-79846-2

Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41.

Author(s): Homan CC, Drazer MW, Yu K, Lawrence DM, Feng J, Arriola-Martinez L, Pozsgai MJ, McNeely KE, Ha T, Venugopal P, Arts P, King-Smith SL, Cheah J, Armstrong M, Wang P, Bödör C, Cantor AB, Cazzola M, Degelman E, DiNardo CD, Duployez N, Favier R, Fröhling S, Rio-Machin A, Klco JM, Krämer A, Kurokawa M, Lee J, Malcovati L, Morgan NV, Natsoulis G, Owen C, Patel KP, Preudhomme C, Raslova H, Rienhoff H,
Published in: Blood Advances, 2023, ISSN 2473-9529
Publisher: Elsevier
DOI: 10.1182/bloodadvances.2023010045

SerpinB10, a Serine Protease Inhibitor, Is Implicated in UV-Induced Cellular Response

Author(s): Hajnalka Majoros, Barbara N. Borsos, Zsuzsanna Ujfaludi, Zoltán G. Páhi, Mónika Mórocz, Lajos Haracska, Imre Miklós Boros, Tibor Pankotai
Published in: International Journal of Molecular Sciences, Issue 22/16, 2021, Page(s) 8500, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22168500

Regenerative Neurology and Regenerative Cardiology: Shared Hurdles and Achievements

Author(s): Mitrečić D, Hribljan V, Jagečić D, Isaković J, Lamberto F, Horánszky A, Zana M, Foldes G, Zavan B, Pivoriūnas A, Martinez S, Mazzini L, Radenovic L, Milasin J, Chachques JC, Buzanska L, Song MS, Dinnyés A.
Published in: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23020855

Chronic treatment with rofecoxib but not ischemic preconditioning of the myocardium ameliorates early intestinal damage following cardiac ischemia/reperfusion injury in rats

Author(s): Szilvia B. László, Bernadette Lázár, Gábor B. Brenner, András Makkos, Mihály Balogh, Mahmoud Al-Khrasani, Barbara Hutka, Amir Mohammadzadeh, Ágnes Kemény, Terézia László, Bálint Scheich, Tamara Szabados, Éva Kenyeres, Zoltán Giricz, Péter Bencsik, Zoltán V. Varga, Julianna Novák, Zsuzsanna Helyes, Péter Ferdinandy, Klára Gyires, Zoltán S. Zádori
Published in: Biochemical Pharmacology, Issue 178, 2020, Page(s) 114099, ISSN 0006-2952
Publisher: Elsevier BV
DOI: 10.1016/j.bcp.2020.114099

Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.

Author(s): Bullinger L, Rosenquist R, Vassilakopoulos TP, Ott G, Ogawa S, Damm F.
Published in: Leukemia, 2023, ISSN 0887-6924
Publisher: Nature Publishing Group
DOI: 10.1038/s41375-023-02013-9

MMP-9 as Prognostic Marker for Brain Tumours: A Comparative Study on Serum-Derived Small Extracellular Vesicles.

Author(s): Dobra G, Gyukity-Sebestyén E, Bukva M, Harmati M, Nagy V, Szabó Z, Pankotai T, Klekner Á, Buzás K.
Published in: Cancers, 2023, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15030712

BRAF RNA is prognostic and widely expressed in lung adenocarcinoma.

Author(s): Dora D, Vörös I, Varga ZV, Takacs P, Teglasi V, Moldvay J, Lohinai Z.
Published in: Translational Lung Cancer Research, 2023, ISSN 2218-6751
Publisher: Society for Translational Medicine
DOI: 10.21037/tlcr-22-449

Heart failure pharmacotherapy and cancer: pathways and pre-clinical/clinical evidence.

Author(s): Sayour, N. V., Paál, Á. M., Ameri, P., Meijers, W. C., Minotti, G., Andreadou, I., Lombardo, A., Camilli, M., Drexel, H., Grove, E. L., Dan, G. A., Ivanescu, A., Semb, A. G., Savarese, G., Dobrev, D., Crea, F., Kaski, J. C., de Boer, R. A., Ferdinandy, P., & Varga, Z. V.
Published in: European heart journal, 2024, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehae105

Reviewing critical TRPM2 variants through a structure-function lens

Author(s): Tóth, Á. V., & Bartók, Á.
Published in: Journal of biotechnology, 2024, ISSN 0168-1656
Publisher: Elsevier BV
DOI: 10.1016/j.jbiotec.2024.02.017

IL-36α and Lipopolysaccharide Cooperatively Induce Autophagy by Triggering Pro-Autophagic Biased Signaling

Author(s): Zaid I. I. Al-Luhaibi, Áron Dernovics, György Seprényi, Ferhan Ayaydin, Zsolt Boldogkői, Zoltán Veréb, Klára Megyeri
Published in: Biomedicines, Issue 9/11, 2021, Page(s) 1541, ISSN 2227-9059
Publisher: MDPI AG
DOI: 10.3390/biomedicines9111541

Acquired somatic variants in inherited myeloid malignancies.

Author(s): Armes H, Rio-Machin A, Krizsán S, Bödör C, Kaya F, Bewicke-Copley F, Alnajar J, Walne A, Péterffy B, Tummala H, Rouault-Pierre K, Dokal I, Vulliamy T, Fitzgibbon J.
Published in: Leukemia, 2022, ISSN 0887-6924
Publisher: Nature Publishing Group
DOI: 10.1038/s41375-022-01515-2

BTK and PLCG2 remain unmutated in one third of patients with CLL relapsing on ibrutinib.

Author(s): Bonfiglio S, Sutton LA, Ljungström V, Capasso A, Pandzic T, Weström S, Foroughi-Asl H, Skaftason A, Gellerbring A, Lyander A, Gandini F, Gaidano G, Trentin L, Bonello L, Reda G, Bödör C, Stavroyianni N, Tam CS, Marasca R, Forconi F, Panayiotidis P, Ringshausen I, Jaksic O, Frustaci AM, Iyengar S, Coscia M, Mulligan SP, Ysebaert L, Strugov V, Pavlovsky C, Walewska R, Österborg A, Cortese D, Ra
Published in: Blood Advances, 2023, ISSN 2473-9529
Publisher: Elsevier BV
DOI: 10.1182/bloodadvances.2022008821

Underground metabolism as a rich reservoir for pathway engineering.

Author(s): Kovács SC, Szappanos B, Tengölics R, Notebaart RA, Papp B.
Published in: Bioinformatics, 2022, ISSN 1367-4803
Publisher: Oxford University Press
DOI: 10.1093/bioinformatics/btac282

The Arabidopsis Rho of Plants GTPase ROP1 Is a Potential Calcium-Dependent Protein Kinase (CDPK) Substrate

Author(s): Dalma Ménesi; Éva Klement; Györgyi Ferenc; Attila Fehér
Published in: MDPI, Issue 2, 2021, ISSN 1424-3210
Publisher: MDPI Plants
DOI: 10.3390/plants10102053

Advances in phototherapy for psoriasis and atopic dermatitis

Author(s): Lajos Kemény, Emese Varga, Zoltan Novak
Published in: Expert Review of Clinical Immunology, Issue 15/11, 2019, Page(s) 1205-1214, ISSN 1744-666X
Publisher: Future Drugs Ltd.
DOI: 10.1080/1744666x.2020.1672537

Maternal One-Carbon Metabolism during the Periconceptional Period and Human Foetal Brain Growth: A Systematic Review

Author(s): Eleonora Rubini, Inge M. M. Baijens, Alex Horánszky, Sam Schoenmakers, Kevin D. Sinclair, Melinda Zana, András Dinnyés, Régine P. M. Steegers-Theunissen, Melek Rousian
Published in: Genes, Issue 12/10, 2021, Page(s) 1634, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes12101634

The golden ages of inflammatory skin diseases: skyrocketing developments in the therapy of psoriasis and atopic dermatitis

Author(s): L. Kemény
Published in: Journal of the European Academy of Dermatology and Venereology, Issue 35/11, 2021, Page(s) 2239-2240, ISSN 0926-9959
Publisher: Elsevier BV
DOI: 10.1111/jdv.17655

Hydrogen peroxide production by epidermal dual oxidase 1 regulates nociceptive sensory signals.

Author(s): Pató A, Bölcskei K, Donkó Á, Kaszás D, Boros M, Bodrogi L, Várady G, Pape VFS, Roux BT, Enyedi B, Helyes Z, Watt FM, Sirokmány G, Geiszt M.
Published in: Redox Biology, 2023, ISSN 2213-2317
Publisher: Elsevier BV
DOI: 10.1016/j.redox.2023.102670

Extracellular vesicle release and uptake by the liver under normo- and hyperlipidemia

Author(s): Krisztina Németh, Zoltán Varga, Dorina Lenzinger, Tamás Visnovitz, Anna Koncz, Nikolett Hegedűs, Ágnes Kittel, Domokos Máthé, Krisztián Szigeti, Péter Lőrincz, Clodagh O’Neill, Róisín Dwyer, Zhonglin Liu, Edit I. Buzás, Viola Tamási
Published in: Cellular and Molecular Life Sciences, 2021, ISSN 1420-682X
Publisher: Birkhauser Verlag
DOI: 10.1007/s00018-021-03969-6

Screening and monitoring of the BTK C481S mutation in a real‐world cohort of patients with relapsed/refractory chronic lymphocytic leukaemia during ibrutinib therapy

Author(s): Csaba Bödör, Lili Kotmayer, Tamás László, Ferenc Takács, Gábor Barna, Richárd Kiss, Endre Sebestyén, Tibor Nagy, Lajos László Hegyi, Gábor Mikala, Sándor Fekete, Péter Farkas, Alexandra Balogh, Tamás Masszi, Judit Demeter, Júlia Weisinger, Hussain Alizadeh, Béla Kajtár, Zoltán Kohl, Róbert Szász, Lajos Gergely, Timea Gurbity Pálfi, Adrienn Sulák, Balázs Kollár, Miklós Egy
Published in: British Journal of Haematology, 2021, ISSN 0007-1048
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/bjh.17502

Morphologic and molecular analysis of Richter syndrome in chronic lymphocytic leukaemia patients treated with ibrutinib or venetoclax

Author(s): Ambrus Gángó, Richárd Kiss, Péter Farkas, Eid Hanna, Judit Demeter, Beáta Deák, Dóra Lévai, Lili Kotmayer, Donát Alpár, András Matolcsy, Csaba Bödör, Zoltán Mátrai, Botond Timár
Published in: Pathology, 2021, ISSN 0031-3025
Publisher: Taylor & Francis
DOI: 10.1016/j.pathol.2021.04.008

Novel RICTOR amplification harbouring entities: FISH validation of RICTOR amplification in tumour tissue after next-generation sequencing.

Author(s): Sztankovics D, Krencz I, Moldvai D, Dankó T, Nagy Á, Nagy N, Bedics G, Rókusz A, Papp G, Tőkés AM, Pápay J, Sápi Z, Dezső K, Bödör C, Sebestyén A.
Published in: Scientific Reports, 2023, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-023-46927-x

The EHA Research Roadmap: Malignant Lymphoid Diseases.

Author(s): Dreyling M, André M, Gökbuget N, Tilly H, Jerkeman M, Gribben J, Ferreri A, Morel P, Stilgenbauer S, Fox C, Maria Ribera J, Zweegman S, Aurer I, Bödör C, Burkhardt B, Buske C, Dollores Caballero M, Campo E, Chapuy B, Davies A, de Leval L, Doorduijn J, Federico M, Gaulard P, Gay F, Ghia P, Grønbæk K, Goldschmidt H, Kersten MJ, Kiesewetter B, Landman-Parker J, Le Gouill S, Lenz G, Leppä S, Lo
Published in: HemaSphere, 2022, ISSN 2572-9241
Publisher: Wolters Kluwer Health
DOI: 10.1097/hs9.0000000000000726

Plasminogen activator inhibitor 1 is a novel faecal biomarker for monitoring disease activity and therapeutic response in inflammatory bowel diseases.

Author(s): Jójárt B, Resál T, Kata D, Molnár T, Bacsur P, Szabó V, Varga Á, Szántó KJ, Pallagi P, Földesi I, Molnár T, Maléth J, Farkas K.
Published in: Journal of Corhn's Colitis, 2023, ISSN 1873-9946
Publisher: Elsevier Science
DOI: 10.1093/ecco-jcc/jjad160

Alcohol in Psoriasis—From Bench to Bedside

Author(s): Zita Szentkereszty-Kovács, Krisztián Gáspár, Andrea Szegedi, Lajos Kemény, Dóra Kovács, Dániel Törőcsik
Published in: International Journal of Molecular Sciences, Issue 22/9, 2021, Page(s) 4987, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22094987

Chronic Cerebral Hypoperfusion-Induced Disturbed Proteostasis of Mitochondria and MAM Is Reflected in the CSF of Rats by Proteomic Analysis.

Author(s): Tukacs V, Mittli D, Hunyadi-Gulyás É, Hlatky D, Medzihradszky KF, Darula Z, Nyitrai G, Czurkó A, Juhász G, Kardos J, Kékesi KA.
Published in: Molecular Neurobiology, 2023, ISSN 0893-7648
Publisher: Humana Press, Inc.
DOI: 10.1007/s12035-023-03215-z

The Combination of Single-Cell and Next-Generation Sequencing Can Reveal Mosaicism for BRCA2 Mutations and the Fine Molecular Details of Tumorigenesis

Author(s): Alexandra Gráf, Márton Zsolt Enyedi, Lajos Pintér, Éva Kriston-Pál, Gábor Jaksa, Árpád Bálind, Éva Ezer, Péter Horváth, Farkas Sükösd, Ernő Kiss, Lajos Haracska
Published in: Cancers, Issue 13/10, 2021, Page(s) 2354, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13102354

Environmental Alterations during Embryonic Development: Studying the Impact of Stressors on Pluripotent Stem Cell-Derived Cardiomyocytes

Author(s): Federica Lamberto, Irene Peral-Sanchez, Suchitra Muenthaisong, Melinda Zana, Sandrine Willaime-Morawek, András Dinnyés
Published in: Genes, Issue 12/10, 2021, Page(s) 1564, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes12101564

Exploring RAD18-dependent replication of damaged DNA and discontinuities: A collection of advanced tools.

Author(s): Mórocz M, Qorri E, Pekker E, Tick G, Haracska L.
Published in: Journal of Biotechnology, 2024, ISSN 0168-1656
Publisher: Elsevier BV
DOI: 10.1016/j.jbiotec.2023.12.001

Genetic Investigation of Inverse Psoriasis

Author(s): Anikó Göblös, Emese Varga, Katalin Farkas, Kristóf Árvai, Lajos Kemény
Published in: Life, Issue 11/7, 2021, Page(s) 654, ISSN 2075-1729
Publisher: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/life11070654

Mitochondrial dysfunction and immune suppression in BRAF V600E‐mutated metastatic melanoma

Author(s): Natália Pinto de Almeida, Ágnes Judit Jánosi, Runyu Hong, Ahmad Rajeh, Fábio Nogueira, Leticia Szadai, Beata Szeitz, Indira Pla Parada, Viktória Doma, Nicole Woldmar, Jéssica Guedes, Zsuzsanna Újfaludi, Aron Bartha, Yonghyo Kim, Charlotte Welinder, Bo Baldetorp, Lajos Vince Kemény, Zoltan Pahi, Guihong Wan, Nga Nguyen, Tibor Pankotai, Balázs Győrffy, Krzysztof Pawłowski, Peter Horvatovi
Published in: Clinical and Translational Medicine, Issue 14, 2024, ISSN 2001-1326
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/ctm2.1773

Deep Proteomic Analysis on Biobanked Paraffine-Archived Melanoma with Prognostic/Predictive Biomarker Read-Out.

Author(s): Szadai L, Velasquez E, Szeitz B, Almeida NPd, Domont G, Betancourt LH, Gil J, Marko-Varga M, Oskolas H, Jánosi ÁJ, Boyano-Adánez MdC, Kemény L, Baldetorp B, Malm J, Horvatovich P, Szász AM, Németh IB, Marko-Varga G.
Published in: Cancers, 2021, Page(s) 13(23):6105, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13236105

HCN channels at the cell soma ensure the rapid electrical reactivity of fast-spiking interneurons in human neocortex.

Author(s): Szegedi V, Bakos E, Furdan S, Kovács BH, Varga D, Erdélyi M, Barzó P, Szücs A, Tamás G, Lamsa K.
Published in: PlOS Biology, 2023, ISSN 1544-9173
Publisher: Public Library of Science
DOI: 10.1371/journal.pbio.3002001

Parathyroid cancer with MTOR gene mutation: Case report and review of the literature.

Author(s): Stark J, Tőke J, Huszty G, Nagy P, Bedics G, Bödör C, Tímár J, Tóth M.
Published in: Annales d'Endocrinologie, 2023, ISSN 0003-4266
Publisher: Elsevier Masson
DOI: 10.1016/j.ando.2023.06.003

Tamás SX, Roux BT, Vámosi B, Dehne FG, Török A, Fazekas L, Enyedi B.

Author(s): A genetically encoded sensor for visualizing leukotriene B4 gradients in vivo.
Published in: Nature Communications, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-40326-6

Fibroblast-Derived Extracellular Vesicles Induce Colorectal Cancer Progression by Transmitting Amphiregulin

Author(s): Ádám Oszvald, Zsuzsanna Szvicsek, Márton Pápai, Andrea Kelemen, Zoltán Varga, Tamás Tölgyes, Kristóf Dede, Attila Bursics, Edit I. Buzás, Zoltán Wiener
Published in: Frontiers in Cell and Developmental Biology, Issue 8, 2020, ISSN 2296-634X
Publisher: Frontiers Media S.A.
DOI: 10.3389/fcell.2020.00558

Understanding Differences in Sex-Based Outcomes with Dual Antiplatelet Therapy After Percutaneous Coronary Intervention

Author(s): Ibrahim Akin, Nazha Hamdani, Ibrahim El-Battrawy
Published in: Drugs, Issue 84, 2024, Page(s) 703-705, ISSN 0012-6667
Publisher: Adis International Ltd.
DOI: 10.1007/s40265-024-02041-4

PACAP-38 and PAC1 Receptor Alterations in Plasma and Cardiac Tissue Samples of Heart Failure Patients.

Author(s): Szabó D, Sárszegi Z, Polgár B, Sághy É, Reglődi D, Tóth T, Onódi Z, Leszek P, Varga ZV, Helyes Z, Kemény Á, Ferdinandy P, Tamás A.
Published in: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23073715

CD3+/CD56+ NKT-like Cells Show Imbalanced Control Immediately after Exercise in Delayed-Onset Muscle Soreness.

Author(s): Sonkodi B, Pállinger É, Radovits T, Csulak E, Shenker-Horváth K, Kopper B, Buzás EI, Sydó N, Merkely B.
Published in: International Journal of Molecular Sciences, Issue 14220067, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms231911117

Genomic Landscape of Normal and Breast Cancer Tissues in a Hungarian Pilot Cohort.

Author(s): Pipek O, Alpár D, Rusz O, Bödör C, Udvarnoki Z, Medgyes-Horváth A, Csabai I, Szállási Z, Madaras L, Kahán Z, Cserni G, Kővári B, Kulka J, Tőkés AM.
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24108553

Initial and ongoing tobacco smoking elicits vascular damage and distinct inflammatory response linked to neurodegeneration.

Author(s): Garza AP, Morton L, Pállinger É, Buzás EI, Schreiber S, Schott BH, Dunay IR.
Published in: Brain, Behaviour and Immunity, 2023, ISSN 0889-1591
Publisher: Academic Press
DOI: 10.1016/j.bbih.2023.100597

Lipids and Trehalose Actively Cooperate in Heat Stress Management of Schizosaccharomyces pombe.

Author(s): Péter M, Gudmann P, Kóta Z, Török Z, Vígh L, Glatz A, Balogh G.
Published in: Journal of Molecular Sciences, 2021, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms222413272

Negative trade-off between neoantigen repertoire breadth and the specificity of HLA-I molecules shapes antitumor immunity

Author(s): Máté Manczinger, Balázs Koncz, Gergő Mihály Balogh, Benjamin Tamás Papp, Leó Asztalos, Lajos Kemény, Balázs Papp, Csaba Pál
Published in: Nature Cancer, 2021, ISSN 2662-1347
Publisher: Nature Research (subsidiary of Springer Nature)
DOI: 10.1038/s43018-021-00226-4

Complex treatment of residual metastatic germ cell cancer: A single center experience

Author(s): Fruzsina Eszter Fazekas, Zsuzsanna Ujfaludi, Krisztina Biró, Zoltán Gábor Páhi, István Buzogány, Farkas Sükösd, Tibor Pankotai, Tamás Beöthe
Published in: Journal of Biotechnology, Issue 389, 2024, Page(s) 61-67, ISSN 0168-1656
Publisher: Elsevier BV
DOI: 10.1016/j.jbiotec.2024.04.018

Development and Functional Characterization of a Versatile Radio-/Immunotheranostic Tool for Prostate Cancer Management.

Author(s): Arndt C, Bergmann R, Striese F, Merkel K, Máthé D, Loureiro LR, Mitwasi N, Kegler A, Fasslrinner F, González Soto KE, Neuber C, Berndt N, Kovács N, Szöllősi D, Hegedűs N, Tóth G, Emmermann J-P, Harikumar KB, Kovacs T, Bachmann M, Feldmann A.
Published in: Cancers, 2022, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14081996

Parallel testing of liquid biopsy (ctDNA) and tissue biopsy samples reveals a higher frequency of EZH2 mutations in follicular lymphoma.

Author(s): Timár B, Csomor J, Tóth E, Schneider T, Mikala G, Matolcsy A, Alpár D, Masszi A, Bödör C.
Published in: Journal of Internal Medicine, 2023, ISSN 0954-6820
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/joim.13674

Intraperitoneal Glucose Transport to Micrometastasis: A Multimodal In Vivo Imaging Investigation in a Mouse Lymphoma Model

Author(s): Zsombor Ritter, Katalin Zámbó, Xinkai Jia, Dávid Szöllősi, Dániel Dezső, Hussain Alizadeh, Ildikó Horváth, Nikolett Hegedűs, David Tuch, Kunal Vyas, Péter Balogh, Domokos Máthé, Erzsébet Schmidt
Published in: International Journal of Molecular Sciences, Issue 22/9, 2021, Page(s) 4431, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22094431

β-Endorphin mediates radiation therapy fatigue.

Author(s): Hermann AL, Fell GL, Kemény LV, Fung CY, Held KD, Biggs PJ, Rivera PD, Bilbo SD, Igras V, Willers H, Kung J, Gheorghiu L, Hideghéty K, Mao J, Woolf CJ, Fisher DE.
Published in: Science advances, 2022, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abn6025

Anticancer Potential of L-Histidine-Capped Silver Nanoparticles against Human Cervical Cancer Cells (SiHA).

Author(s): Mohammed Asik R, Manikkaraja C, Tamil Surya K, Suganthy N, Priya Aarthy A, Mathe D, Sivakumar M, Archunan G, Padmanabhan P, Gulyas B.
Published in: Nanomaterials, 2021, ISSN 2079-4991
Publisher: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/nano11113154

Supraoptimal Iron Nutrition of Brassica napus Plants Suppresses the Iron Uptake of Chloroplasts by Down-Regulating Chloroplast Ferric Chelate Reductase

Author(s): Máté Sági-Kazár, Helga Zelenyánszki, Brigitta Müller, Barnabás Cseh, Balázs Gyuris, Sophie Z. Farkas, Ferenc Fodor, Brigitta Tóth, Béla Kovács, Anna Koncz, Tamás Visnovitz, Edit I. Buzás, Barbara Bánkúti, Ferenc Bánáti, Kálmán Szenthe and Ádám Solti
Published in: Frontiers in Plant Science, 2021, Page(s) 12/748, ISSN 1664-462X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fpls.2021.658987

Membrane Domain Localization and Interaction of the Prion-Family Proteins, Prion and Shadoo with Calnexin.

Author(s): Dondapati DT, Cingaram PR, Ayaydin F, Nyeste A, Kanyó A, Welker E, Fodor E.
Published in: MDPI Membranes, 2021, ISSN 2077-0375
Publisher: Molecular Diversity Preservation International
DOI: 10.3390/membranes11120978

A Photo-clickable ATP-Mimetic Reveals Nucleotide Interactors in the Membrane Proteome

Author(s): Mark Jelcic, Ke Wang, King Lam Hui, Xiao-Chuan Cai, Balázs Enyedi, Minkui Luo, Philipp Niethammer
Published in: Cell Chemical Biology, Issue 27/8, 2020, Page(s) 1073-1083.e12, ISSN 2451-9456
Publisher: Elsevier Inc.
DOI: 10.1016/j.chembiol.2020.05.010

The effect of antifungal resistance development on the virulence of Candida species.

Author(s): Bohner F, Papp C, Gácser A.
Published in: FEMS Yeast Research, 2022, ISSN 1567-1356
Publisher: Blackwell
DOI: 10.1093/femsyr/foac019

Functionalized Mesoporous Silica Nanoparticles for Drug-Delivery to Multidrug-Resistant Cancer Cells.

Author(s): Igaz N, Bélteky P, Kovács D, Papp C, Rónavári A, Szabó D, Gácser A, Kónya Z, Kiricsi M.
Published in: International Journal of Nanomedicine, 2022, ISSN 1176-9114
Publisher: Dove Medical Press Ltd
DOI: 10.2147/ijn.s363952

Thrombocytosis and Effects of IL-6 Knock-Out in a Colitis-Associated Cancer Model

Author(s): Valeria Josa, Szilamer Ferenczi, Rita Szalai, Eniko Fuder, Daniel Kuti, Krisztina Horvath, Nikolett Hegedus, Tibor Kovacs, Gergo Bagamery, Balazs Juhasz, Zsuzsanna Winkler, Daniel S. Veres, Zsombor Zrubka, Domokos Mathe, Zsolt Baranyai
Published in: International Journal of Molecular Sciences, Issue 21/17, 2020, Page(s) 6218, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21176218

Novel, clinically relevant genomic patterns identified by comprehensive genomic profiling in ATRX-deficient IDH-wildtype adult high-grade gliomas.

Author(s): Bedics G, Szőke P, Bátai B, Nagy T, Papp G, Kránitz N, Rajnai H, Reiniger L, Bödör C, Scheich B.
Published in: Scienntific Reports, 2023, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-023-45786-w

CD44 Expression Intensity Marks Colorectal Cancer Cell Subpopulations with Different Extracellular Vesicle Release Capacity.

Author(s): Kelemen A, Carmi I, Seress I, Lőrincz P, Tölgyes T, Dede K, Bursics A, Buzás EI, Wiener Z.
Published in: International journal of molecular sciences, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23042180

Balanced Intense Exercise Training Induces Atrial Oxidative Stress Counterbalanced by the Antioxidant System and Atrial Hypertrophy That Is Not Associated with Pathological Remodeling or Arrhythmogenicity

Author(s): Attila Oláh, Bálint András Barta, Alex Ali Sayour, Mihály Ruppert, Eszter Virág-Tulassay, Julianna Novák, Zoltán V. Varga, Péter Ferdinandy, Béla Merkely, Tamás Radovits
Published in: Antioxidants, Issue 10/3, 2021, Page(s) 452, ISSN 2076-3921
Publisher: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/antiox10030452

Self-mediated positive selection of T cells sets an obstacle to the recognition of nonself

Author(s): Balázs Koncz, Gergő M. Balogh, Benjamin T. Papp, Leó Asztalos, Lajos Kemény, Máté Manczinger
Published in: Proceedings of the National Academy of Sciences, Issue 118/37, 2021, Page(s) e2100542118, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2100542118

Reinstating olfactory bulb-derived limbic gamma oscillations alleviates depression-like behavioral deficits in rodents.

Author(s): Li Q, Takeuchi Y, Wang J, Gellért L, Barcsai L, Pedraza LK, Nagy AJ, Kozák G, Nakai S, Kato S, Kobayashi K, Ohsawa M, Horváth G, Kékesi G, Lőrincz ML, Devinsky O, Buzsáki G, Berényi A.
Published in: Neuron, 2023, ISSN 1097-4199
Publisher: Cell Press
DOI: 10.1016/j.neuron.2023.04.013

Impaired regulation of PMCA activity by defective CFTR expression promotes epithelial cell damage in alcoholic pancreatitis and hepatitis

Author(s): Madácsy T, Varga Á, Papp N, Tél B, Pallagi P, Szabó V, Kiss A, Fanczal J, Rakonczay Z Jr, Tiszlavicz L, Rázga Z, Hohwieler M, Kleger A, Gray M, Hegyi P, Maléth J
Published in: Cellular and Molecular Life Sciences, 2022, ISSN 1420-682X
Publisher: Birkhauser Verlag
DOI: 10.1007/s00018-022-04287-1

Lactobacillus acidophilus, L. plantarum, L. rhamnosus, and L. reuteri Cell-Free Supernatants Inhibit Candida parapsilosis Pathogenic Potential upon Infection of Vaginal Epithelial Cells Monolayer and in a Transwell Coculture System In Vitro.

Author(s): Spaggiari L, Sala A, Ardizzoni A, De Seta F, Singh DK, Gacser A, Blasi E, Pericolini E.
Published in: Microbiology spectrum, 2022, ISSN 2165-0497
Publisher: American Society for Microbiology
DOI: 10.1128/spectrum.02696-21

A single early introduction governed viral diversity in the second wave of SARS-CoV-2 epidemic in Hungary.

Author(s): Ari E, Vásárhelyi BM, Kemenesi G, Tóth GE, Zana B, Somogyi B, Lanszki Z, Röst G, Jakab F, Papp B, Kintses B.
Published in: Virus Evolution, Issue 20571577, 2022, ISSN 2057-1577
Publisher: Oxford University Press
DOI: 10.1093/ve/veac069

Methods for the identification and characterization of extracellular vesicles in cardiovascular studies - from exosomes to microvesicles.

Author(s): Davidson SM, Boulanger CM, Aikawa E, Badimon L, Barile L, Binder CJ, Brisson A, Buzas E, Emanueli C, Jansen F, Katsur M, Lacroix R, Lim SK, Mackman N, Mayr M, Menasché P, Nieuwland R, Sahoo S, Takov K, Thum T, Vader P, Wauben MHM, Witwer K, Sluijter JPG.
Published in: Cardiovascular Research, 2022, ISSN 1755-3245
Publisher: Oxford University Press
DOI: 10.1093/cvr/cvac031

Chronic Exposure to the Food Additive tBHQ Modulates Expression of Genes Related to SARS-CoV-2 and Influenza Viruses.

Author(s): Németh K, Petschner P, Pálóczi K, Fekete N, Pállinger É, Buzás EI, Tamási V.
Published in: Life, 2022, ISSN 2075-1729
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/life12050642

Functional characterization of the transient receptor potential melastatin 2 (TRPM2) cation channel from Nematostella vectensis reconstituted into lipid bilayer.

Author(s): Szollosi A, Almássy J.
Published in: Scientific Reports, 2023, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-023-38640-6

Folate-Targeted Monodisperse PEG-Based Conjugates Made by Chemo-Enzymatic Methods for Cancer Diagnosis and Treatment

Author(s): Krisztina S. Nagy, Krisztina Toth, Eva Pallinger, Angela Takacs, Laszlo Kohidai, Angela Jedlovszky-Hajdu, Domokos Mathe, Noemi Kovacs, Daniel S. Veres, Krisztian Szigeti, Kristof Molnar, Eniko Krisch, Judit E. Puskas
Published in: International Journal of Molecular Sciences, Issue 22/19, 2021, Page(s) 10347, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms221910347

Higher-order thalamic nuclei facilitate the generalization and maintenance of spike-and-wave discharges of absence seizures.

Author(s): Atherton Z, Nagy O, Barcsai L, Sere P, Zsigri N, Földi T, Gellért L, Berényi A, Crunelli V, Lőrincz ML.
Published in: Neurobiology of Disease, 2023, ISSN 0969-9961
Publisher: Academic Press
DOI: 10.1016/j.nbd.2023.106025

Signaling through Syk or CARD9 Mediates Species-Specific Anti- Candida Protection in Bone Marrow Chimeric Mice

Author(s): Erik Zajta, Katalin Csonka, Adél Tóth, Laszló Tiszlavicz, Tamás Németh, Anita Orosz, Ádám Novák, Máté Csikós, Csaba Vágvölgyi, Attila Mócsai, Attila Gácser
Published in: mBio, Issue 12/4, 2021, ISSN 2150-7511
Publisher: American Society for Microbiology
DOI: 10.1128/mbio.01608-21

Integrated evolutionary analysis reveals antimicrobial peptides with limited resistance

Author(s): Réka Spohn, Lejla Daruka, Viktória Lázár, Ana Martins, Fanni Vidovics, Gábor Grézal, Orsolya Méhi, Bálint Kintses, Mónika Számel, Pramod K. Jangir, Bálint Csörgő, Ádám Györkei, Zoltán Bódi, Anikó Faragó, László Bodai, Imre Földesi, Diána Kata, Gergely Maróti, Bernadett Pap, Roland Wirth, Balázs Papp, Csaba Pál
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-12364-6

Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action

Author(s): Bálint Kintses, Pramod K. Jangir, Gergely Fekete, Mónika Számel, Orsolya Méhi, Réka Spohn, Lejla Daruka, Ana Martins, Ali Hosseinnia, Alla Gagarinova, Sunyoung Kim, Sadhna Phanse, Bálint Csörgő, Ádám Györkei, Eszter Ari, Viktória Lázár, István Nagy, Mohan Babu, Csaba Pál, Balázs Papp
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-13618-z

Unmatched level of molecular convergence among deeply divergent complex multicellular fungi

Author(s): Zsolt Merényi, Arun N Prasanna, Zheng Wang, Károly Kovács, Botond Hegedüs, Balázs Bálint, Balázs Papp, Jeffrey P Townsend, László G Nagy
Published in: Molecular Biology and Evolution, 2020, ISSN 0737-4038
Publisher: Oxford University Press
DOI: 10.1093/molbev/msaa077

Rapid decline of bacterial drug-resistance in an antibiotic-free environment through phenotypic reversion

Author(s): Anett Dunai, Réka Spohn, Zoltán Farkas, Viktória Lázár, Ádám Györkei, Gábor Apjok, Gábor Boross, Balázs Szappanos, Gábor Grézal, Anikó Faragó, László Bodai, Balázs Papp, Csaba Pál
Published in: eLife, 2019, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.47088.001

Activity-based protein profiling of the human failing ischemic heart reveals alterations in hydrolase activities involving the endocannabinoid system

Author(s): Annelot C.M. van Esbroeck, Zoltan V. Varga, Xinyu Di, Eva J. van Rooden, Viktória E. Tóth, Zsófia Onódi, Mariusz Kuśmierczyk, Przemyslaw Leszek, Péter Ferdinandy, Thomas Hankemeier, Mario van der Stelt, Pál Pacher
Published in: Pharmacological Research, Issue 151, 2020, Page(s) 104578, ISSN 1043-6618
Publisher: Academic Press
DOI: 10.1016/j.phrs.2019.104578

Extracellular vesicles transmit epithelial growth factor activity in the intestinal stem cell niche

Author(s): Ádám Oszvald, Zsuzsanna Szvicsek, Gyöngyvér Orsolya Sándor, Andrea Kelemen, András Áron Soós, Krisztina Pálóczi, Attila Bursics, Kristóf Dede, Tamás Tölgyes, Edit I. Buzás, Anikó Zeöld, Zoltán Wiener
Published in: STEM CELLS, 2019, ISSN 1066-5099
Publisher: AlphaMed Press Inc
DOI: 10.1002/stem.3113

Unravelling the Role of Trophoblastic-Derived Extracellular Vesicles in Regulatory T Cell Differentiation

Author(s): Árpád Ferenc Kovács, Nóra Fekete, Lilla Turiák, András Ács, László Kőhidai, Edit I. Buzás, Éva Pállinger
Published in: International Journal of Molecular Sciences, Issue 20/14, 2019, Page(s) 3457, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20143457

Cartilage Oligomeric Matrix Protein Negatively Influences Keratinocyte Proliferation Via α5β1-Integrin: Potential Relevance of Altered Cartilage Oligomeric Matrix Protein Expression in Psoriasis

Author(s): Renáta Bozó, Edit Szél, Judit Danis, Barbara Gubán, Zsuzsanna Bata-Csörgő, Kornélia Szabó, Lajos Kemény, Gergely Groma
Published in: Journal of Investigative Dermatology, 2020, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2019.12.037

Comprehensive Proteomic Analysis Reveals Intermediate Stage of Non-Lesional Psoriatic Skin and Points out the Importance of Proteins Outside this Trend

Author(s): Edit Szél, Renáta Bozó, Éva Hunyadi-Gulyás, Máté Manczinger, Kornélia Szabó, Lajos Kemény, Zsuzsanna Bata-Csörgő, Gergely Groma
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-47774-5

Targeting the gut‐skin axis—Probiotics as new tools for skin disorder management?

Author(s): Magdolna Szántó, Anikó Dózsa, Dóra Antal, Kornélia Szabó, Lajos Kemény, Péter Bai
Published in: Experimental Dermatology, Issue 28/11, 2019, Page(s) 1210-1218, ISSN 0906-6705
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/exd.14016

Exploring the fitness benefits of genome reduction in Escherichia coli by a selection-driven approach

Author(s): Viktor Vernyik, Ildikó Karcagi, Edit Tímár, István Nagy, Ádám Györkei, Balázs Papp, Zsuzsanna Györfy, György Pósfai
Published in: Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-020-64074-5

Multilevel structure–activity profiling reveals multiple green tea compound families that each modulate ubiquitin-activating enzyme and ubiquitination by a distinct mechanism

Author(s): Gabriel Fenteany, Paras Gaur, Lili Hegedűs, Kata Dudás, Ernő Kiss, Edit Wéber, László Hackler, Tamás Martinek, László G. Puskás, Lajos Haracska
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-48888-6

Robust high-throughput assays to assess discrete steps in ubiquitination and related cascades

Author(s): Gabriel Fenteany, Paras Gaur, Gaurav Sharma, Lajos Pintér, Ernő Kiss, Lajos Haracska
Published in: BMC Molecular and Cell Biology, Issue 21/1, 2020, ISSN 2661-8850
Publisher: Springer Nature
DOI: 10.1186/s12860-020-00262-5

The Role of P2X7 Receptor in Alzheimer’s Disease

Author(s): Linda Francistiová, Carolina Bianchi, Caterina Di Lauro, Álvaro Sebastián-Serrano, Laura de Diego-García, Julianna Kobolák, András Dinnyés, Miguel Díaz-Hernández
Published in: Frontiers in Molecular Neuroscience, Issue 13, 2020, ISSN 1662-5099
Publisher: Frontiers Research Foundation
DOI: 10.3389/fnmol.2020.00094

Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System

Author(s): Kinga Tóth, Dorottya Ádám, Tamás Bíró, Attila Oláh
Published in: Molecules, Issue 24/5, 2019, Page(s) 918, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules24050918

Nicotinic acid suppresses sebaceous lipogenesis of human sebocytes via activating hydroxycarboxylic acid receptor 2 (HCA 2 )

Author(s): Arnold Markovics, Kinga Fanni Tóth, Katalin Eszter Sós, József Magi, Adrienn Gyöngyösi, Zoltán Benyó, Christos C. Zouboulis, Tamás Bíró, Attila Oláh
Published in: Journal of Cellular and Molecular Medicine, Issue 23/9, 2019, Page(s) 6203-6214, ISSN 1582-1838
Publisher: Wiley-Blackwell
DOI: 10.1111/jcmm.14505

Advances in the optimisation of therapeutic drug monitoring using serum, tissue and faecal anti-tumour necrosis factor concentration in patients with inflammatory bowel disease treated with TNF-α antagonists

Author(s): Kata Judit Szántó, Tamara Madácsy, Diána Kata, Tamás Ferenci, Mariann Rutka, Anita Bálint, Renáta Bor, Anna Fábián, Ágnes Milassin, Boldizsár Jójárt, Zoltán Szepes, Ferenc Nagy, Tamás Molnár, Imre Földesi, József Maléth & Klaudia Farkas
Published in: Expert Opinion on Biological Therapy, 2021, ISSN 1744-7682
Publisher: Taylor & Francis Ltd.
DOI: 10.1080/14712598.2021.1890712

Myelofibrosis progression grading based on type-I and type-III collagen and fibrillin-1 expression boosted by whole slide image analysis.

Author(s): Szekely T, Wichmann B, Maros ME, Csizmadia A, Bodor C, Timar B, Krenacs T.
Published in: Histopathology, Issue 03090167, 2022, ISSN 0309-0167
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/his.14846

Optimization of the Heterologous Expression of the Cannabinoid Type-1 (CB1) Receptor

Author(s): Viktória B. Horváth, Eszter Soltész-Katona, Éva Wisniewski, Anikó Rajki, Eszter Halász, Balázs Enyedi, László Hunyady, András Dávid Tóth, Gergő Szanda
Published in: Frontiers in Endocrinology, Issue 12, 2021, ISSN 1664-2392
Publisher: Frontiers Media S.A.
DOI: 10.3389/fendo.2021.740913

Acquired Triazole Resistance Alters Pathogenicity-Associated Features in Candida auris in an Isolate-Dependent Manner.

Author(s): Bohner F, Papp C, Takacs T, Varga M, Szekeres A, Nosanchuk JD, Vágvölgyi C, Tóth R, Gacser A.
Published in: Journal of Fungi, 2023, ISSN 2309-608X
Publisher: MDPI
DOI: 10.3390/jof9121148

Phenol-Soluble Modulin α3 Stimulates Autophagy in HaCaT Keratinocytes.

Author(s): Dernovics Á, Seprényi G, Rázga Z, Ayaydin F, Veréb Z, Megyeri K.
Published in: Biomedicines, 2023, ISSN 2227-9059
Publisher: MDPI
DOI: 10.3390/biomedicines11113018

Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells

Author(s): Markus Breunig, Jessica Merkle, Martin Wagner, Michael K. Melzer, Thomas F.E. Barth, Thomas Engleitner, Johannes Krumm, Sandra Wiedenmann, Christian M. Cohrs, Lukas Perkhofer, Gaurav Jain, Jana Krüger, Patrick C. Hermann, Maximilian Schmid, Tamara Madácsy, Árpád Varga, Joscha Griger, Ninel Azoitei, Martin Müller, Oliver Wessely, Pamela G. Robey, Sandra Heller, Zahra Dantes, Maximilian Reicher
Published in: Cell Stem Cell, 2021, ISSN 1934-5909
Publisher: Cell Press
DOI: 10.1016/j.stem.2021.03.005

Author Correction: Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling

Author(s): Eric Schoger, Federico Bleckwedel, Giulia Germena, Cheila Rocha, Petra Tucholla, Izzatullo Sobitov, Wiebke Möbius, Maren Sitte, Christof Lenz, Mostafa Samak, Rabea Hinkel, Zoltán V. Varga, Zoltán Giricz, Gabriela Salinas, Julia C. Gross, Laura C. Zelarayán
Published in: Communications Biology, Issue 7, 2024, ISSN 2399-3642
Publisher: Springer Nature
DOI: 10.1038/s42003-024-06319-x

Histone and Histone Acetylation-Related Alterations of Gene Expression in Uninvolved Psoriatic Skin and Their Effects on Cell Proliferation, Differentiation, and Immune Responses.

Author(s): Romhányi D, Szabó K, Kemény L, Groma G.
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms241914551

Development of a Large-Scale Pathogen Screening Test for the Biosafety Evaluation of Canine Mesenchymal Stem Cells.

Author(s): Pekker E, Priskin K, Szabó-Kriston É, Csányi B, Buzás-Bereczki O, Adorján L, Szukacsov V, Pintér L, Rusvai M, Cooper P, Kiss-Tóth E, Haracska L.
Published in: Biological Procedures Online, 2023, ISSN 1480-9222
Publisher: BioMed Central
DOI: 10.1186/s12575-023-00226-x

No beneficial use of the wearable cardioverter defibrillator among patients suffering from inherited and congenital heart disease: data from a European multicenter registry

Author(s): Katharina Koepsel, Tobias C. Dreher, Christian Blockhaus, Michael Gotzmann, Norbert Klein, Thomas Kuntz, Dong-In Shin, Hendrik Lapp, Fabian Schiedat, Mohammad Abumayyaleh, Thomas Beiert, Christian Weth, Boldizsar Kovacs, Stephanie Rosenkaimer, Jacqueline Kowitz, Ardan Muammer Saguner, Julia W. Erath, Firat Duru, Andreas Mügge, Ibrahim Akin, Assem Aweimer, Nazha Hamdani, Ibrahim El-Battrawy
Published in: Frontiers in Cardiovascular Medicine, Issue 11, 2024, ISSN 2297-055X
Publisher: Frontiers Media SA
DOI: 10.3389/fcvm.2024.1384736

Cardiac miRNA Expression and their mRNA Targets in a Rat Model of Prediabetes

Author(s): Éva Sághy, Imre Vörös, Bence Ágg, Bernadett Kiss, Gábor Koncsos, Zoltán V. Varga, Anikó Görbe, Zoltán Giricz, Rainer Schulz, Péter Ferdinandy
Published in: International Journal of Molecular Sciences, Issue 21/6, 2020, Page(s) 2128, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21062128

Nodular fasciitis: a comprehensive, time-correlated investigation of 17 cases

Author(s): Zoltán Sápi, Zoltán Lippai, Gergő Papp, Lajos Hegyi, Johanna Sápi, Katalin Dezső, Károly Szuhai
Published in: Modern Pathology, 2021, ISSN 0893-3952
Publisher: Nature Publishing Group
DOI: 10.1038/s41379-021-00883-x

The Wisdom in Teeth: Neuronal Differentiation of Dental Pulp Cells.

Author(s): Sramkó B, Földes A, Kádár K, Varga G, Zsembery Á, Pircs K.
Published in: Cellular Reprogramming, 2023, ISSN 2152-4971
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/cell.2022.0102

A complete nicotinate degradation pathway in the microbial eukaryote Aspergillus nidulans.

Author(s): Bokor E, Ámon J, Varga M, Szekeres A, Hegedűs Z, Jakusch T, Szakonyi Z, Flipphi M, Vágvölgyi C, Gácser A, Scazzocchio C, Hamari Z.
Published in: Communications Biology, 2022, ISSN 2399-3642
Publisher: Springer Nature
DOI: 10.1038/s42003-022-03684-3

Periodontitis: a newly identified comorbidity in psoriasis and psoriatic arthritis

Author(s): Szandra Dalmády, Lajos Kemény, Márk Antal, Rolland Gyulai
Published in: Expert Review of Clinical Immunology, Issue 16/1, 2020, Page(s) 101-108, ISSN 1744-666X
Publisher: Future Drugs Ltd.
DOI: 10.1080/1744666x.2019.1700113

An Implantable Magneto-Responsive Poly(aspartamide) Based Electrospun Scaffold for Hyperthermia Treatment.

Author(s): Veres T, Voniatis C, Molnár K, Nesztor D, Fehér D, Ferencz A, Gresits I, Thuróczy G, Márkus BG, Simon F, Nemes NM, García-Hernández M, Reiniger L, Horváth I, Máthé D, Szigeti K, Tombácz E, Jedlovszky-Hajdu A.
Published in: Nanomaterials, 2022, ISSN 2079-4991
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nano12091476

Reduced MC4R signaling alters nociceptive thresholds associated with red hair

Author(s): Kathleen C. Robinson, Lajos V. Kemény, Gillian L. Fell, Andrea L. Hermann, Jennifer Allouche, Weihua Ding, Ajay Yekkirala, Jennifer J. Hsiao, Mack Y. Su, Nicholas Theodosakis, Gabor Kozak, Yuichi Takeuchi, Shiqian Shen, Antal Berenyi, Jianren Mao, Clifford J. Woolf, David E. Fisher
Published in: Science Advances, Issue 7/14, 2021, Page(s) eabd1310, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abd1310

Nanoinjection of extracellular vesicles to single live cells by robotic fluidic force microscopy.

Author(s): Kovács KD, Visnovitz T, Gerecsei T, Peter B, Kurunczi S, Koncz A, Németh K, Lenzinger D, Vukman KV, Balogh A, Rajmon I, Lőrincz P, Székács I, Buzás EI, Horvath R.
Published in: Journal of Extracellular Vesicles, 2023, ISSN 2001-3078
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jev2.12388

Virulence Factors and in-Host Selection on Phenotypes in Infectious Probiotic Yeast Isolates (Saccharomyces ‘boulardii’)

Author(s): Alexandra Imre, Renátó Kovács, Kitti Pázmándi, Dániel Nemes, Ágnes Jakab, Tünde Fekete, Hanna Viktória Rácz, Ilona Dóczi, Ildikó Bácskay, Attila Gácser, Károly Kovács, László Majoros, Zoltán Farkas, István Pócsi, Walter P. Pfliegler
Published in: Journal of Fungi, Issue 7/9, 2021, Page(s) 746, ISSN 2309-608X
Publisher: Journal of Fungi
DOI: 10.3390/jof7090746

In situ lymphoma imaging in a spontaneous mouse model using the Cerenkov Luminescence of F-18 and Ga-67 isotopes.

Author(s): Ritter, Z., Zámbó, K., Balogh, P., Szöllösi, D., Xinkai, J., Balázs, Á., Taba, G., Dezső, D., Horváth, I., Hussain, A., Tuch, D., Vyas, K., Hegedűs, N., Kovács, T., Szigeti, K., Máthé D.,Schmidt, E.
Published in: Scientific reports, 2021, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-03505-3

High fat diet and PCSK9 knockout modulates lipid profile of the liver and changes the expression of lipid homeostasis related genes.

Author(s): Németh K, Tóth B, Sarnyai F, Koncz A, Lenzinger D, Kereszturi É, Visnovitz T, Kestecher BM, Osteikoetxea X, Csala M, Buzás EI, Tamási V.
Published in: Nutrition and Metabolism, 2023, ISSN 1743-7075
Publisher: BioMed Central
DOI: 10.1186/s12986-023-00738-z

Epigenetic Mechanisms of ART-Related Imprinting Disorders: Lessons from iPSC and Mouse Models

Author(s): Alex Horánszky, Jessica L. Becker, Melinda Zana, Anne C. Ferguson-Smith, András Dinnyés
Published in: Genes, Issue 12/11, 2021, Page(s) 1704, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes12111704

Potential role of MAP2K1 mutation in the trans-differentiation of interdigitating dendritic cell sarcoma: Case report and literature review.

Author(s): Jenei A, Bedics G, Erdélyi DJ, Müller J, Györke T, Bödör C, Szepesi Á.
Published in: Frontiers in Pediatrics, Issue 22962360, 2022, ISSN 2296-2360
Publisher: Frontiers Media S.A.
DOI: 10.3389/fped.2022.959307

Droplet Digital PCR Is a Novel Screening Method Identifying Potential Cardiac G-Protein-Coupled Receptors as Candidate Pharmacological Targets in a Rat Model of Pressure-Overload-Induced Cardiac Dysfunction.

Author(s): Sayour NV, Tóth VÉ, Nagy RN, Vörös I, Gergely TG, Onódi Z, Nagy N, Bödör C, Váradi B, Ruppert M, Radovits T, Bleckwedel F, Zelarayán LC, Pacher P, Ágg B, Görbe A, Ferdinandy P, Varga ZV. Droplet
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms241813826

Spinocerebellar Ataxia in a Hungarian Female Patient with a Novel Variant of Unknown Significance in the CCDC88C Gene.

Author(s): Boros FA, Szpisjak L, Bozó R, Kelemen E, Zádori D, Salamon A, Danis J, Kalmár T, Maróti Z, Molnár MJ, Klivényi P, Széll M, Ádám É.
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24032617

Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan.

Author(s): Correia-Melo C, Kamrad S, Tengölics R, Messner CB, Trebulle P, Townsend S, Jayasree Varma S, Freiwald A, Heineike BM, Campbell K, Herrera-Dominguez L, Kaur Aulakh S, Szyrwiel L, Yu JSL, Zelezniak A, Demichev V, Mülleder M, Papp B, Alam MT, Ralser M.
Published in: Cell, 2023, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2022.12.007

A dual role of lysophosphatidic acid type 2 receptor (LPAR2) in nonsteroidal anti-inflammatory drug-induced mouse enteropathy.

Author(s): Hutka B, Várallyay A, László SB, Tóth AS, Scheich B, Paku S, Vörös I, Pós Z, Varga ZV, Norman DD, Balogh A, Benyó Z, Tigyi G, Gyires K, Zádori ZS.
Published in: Acta Pharmacologica Sinica, 2023, ISSN 1671-4083
Publisher: Shanghai Institute of Materia Medica
DOI: 10.1038/s41401-023-01175-7

Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility.

Author(s): White R, Sotillo J, Ancarola ME, Borup A, Boysen AT, Brindley PJ, Buzás EI, Cavallero S, Chaiyadet S, Chalmers IW, Cucher MA, Dagenais M, Davis CN, Devaney E, Duque-Correa MA, Eichenberger RM, Fontenla S, Gasan TA, Hokke CH, Kosanovic M, Kuipers ME, Laha T, Loukas A, Maizels RM, Marcilla A, Mazanec H, Morphew RM, Neophytou K, Nguyen LT, Nolte-'t Hoen E, Povelones M, Robinson MW, Rojas A, Schabuss
Published in: Journal of Extracellular Vesicles, 2023, ISSN 2001-3078
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jev2.12298

Transcriptome and proteome profiling reveals complex adaptations of Candida parapsilosis cells assimilating hydroxyaromatic carbon sources.

Author(s): Cillingová A, Tóth R, Mojáková A, Zeman I, Vrzoňová R, Siváková B, Baráth P, Neboháčová M, Klepcová Z, Brázdovič F, Lichancová H, Hodorová V, Brejová B, Vinař T, Mutalová S, Vozáriková V, Mutti G, Tomáška Ľ, Gácser A, Gabaldón T, Nosek J.
Published in: Plos Genetics, 2022, ISSN 1553-7390
Publisher: Public Library of Science
DOI: 10.1371/journal.pgen.1009815

Cross-Linking Mass Spectrometry on P-Glycoprotein.

Author(s): Gellen G, Klement E, Biwott K, Schlosser G, Kalló G, Csősz É, Medzihradszky KF, Bacso Z.
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms241310627

Erratum to: P459 Expression of SerpinE1, a potential new disease activity marker, reflects therapeutic response in Inflammatory Bowel Disease.

Author(s): Jójárt B, Molnàr T, Szabó V, Varga Á, Resàl T, Szàntó K, Kata D, Földesi I, Molnár T, Maléth J, Farkas K.
Published in: Journal of Chron's and colitis, 2021, ISSN 1873-9946
Publisher: Elsevier Science
DOI: 10.1093/ecco-jcc/jjab160

The psoriatic non-lesional skin: a battlefield of constant fight between susceptibility and protective factors

Author(s): Evelyn Kelemen, Renáta Bozó, Gergely Groma, Zsuzsanna Bata-Csörgő, Lajos Kemény, Judit Danis, Márta Széll
Published in: Journal of Investigative Dermatology, 2021, ISSN 0022-202X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2021.05.020

In planta test system for targeted cellular mutagenesis by injection of oligonucleotides to apical meristem of maize seedlings

Author(s): Feríz Rádi, Bettina Nagy, Györgyi Ferenc, Katalin Török, István Nagy, Zoltán Zombori, Dénes Dudits, Ferhan Ayaydin
Published in: Acta Physiologiae Plantarum, Issue 43/5, 2021, ISSN 0137-5881
Publisher: Agencja Wydawnicza ARIES
DOI: 10.1007/s11738-021-03252-y

Small extracellular vesicle DNA-mediated horizontal gene transfer as a driving force for tumor evolution: Facts and riddles.

Author(s): Valcz G, Újvári B, Buzás EI, Krenács T, Spisák S, Kittel Á, Tulassay Z, Igaz P, Takács I, Molnár B.
Published in: Frontiers in Oncology, 2022, ISSN 2234-943X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.945376

The Utilization of Physiologically Active Molecular Components of Grape Seeds and Grape Marc.

Author(s): Hegedüs I, Andreidesz K, Szentpéteri JL, Kaleta Z, Szabó L, Szigeti K, Gulyás B, Padmanabhan P, Budan F, Máthé D.
Published in: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms231911165

Nod-Like Receptors in Host Defence and Disease at the Epidermal Barrier

Author(s): Judit Danis, Mark Mellett
Published in: International Journal of Molecular Sciences, Issue 22/9, 2021, Page(s) 4677, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22094677

Donor Pericardial Interleukin and Apolipoprotein Levels May Predict the Outcome after Human Orthotopic Heart Transplantation.

Author(s): Pállinger É, Székely A, Töreki E, Bencsáth EZ, Szécsi B, Losoncz E, Oleszka M, Hüttl T, Kosztin A, Buzas EI, Radovits T, Merkely B.
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24076780

The DREAM complex represses growth in response to DNA damage in Arabidopsis

Author(s): Lucas Lang, Aladár Pettkó-Szandtner, Hasibe Tunçay Elbaşı, Hirotomo Takatsuka, Yuji Nomoto, Ahmad Zaki, Stefan Dorokhov, Geert De Jaeger, Dominique Eeckhout, Masaki Ito, Zoltán Magyar, László Bögre, Maren Heese, Arp Schnittger
Published in: Life Science Alliance, Issue 4/12, 2021, Page(s) e202101141, ISSN 2575-1077
Publisher: Life Science Alliance
DOI: 10.26508/lsa.202101141

Microbiome's Universe: Impact on health, disease and cancer treatment

Author(s): Zsuzsánna Réthi-Nagy, Szilvia Juhász
Published in: Journal of Biotechnology, Issue 392, 2024, Page(s) 161-179, ISSN 0168-1656
Publisher: Elsevier BV
DOI: 10.1016/j.jbiotec.2024.07.002

Prognostic potential of CUL3 ligase with differential roles in luminal A and basal type breast cancer tumors

Author(s): Vasiliki Pantazi, Vanda Miklós, Paul Smith, Orsolya Oláh-Németh, Gabriella Pankotai-Bodó, Divya Teja Dondapati, Ferhan Ayaydin, Vincenzo D’Angiolella, Tibor Pankotai
Published in: Scientific Reports, Issue 14, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-024-65692-z

Synthesis and preclinical application of a Prussian blue-based dual fluorescent and magnetic contrast agent (CA).

Author(s): Hegedűs N, Forgách L, Kiss B, Varga Z, Jezsó B, Horváth I, Kovács N, Hajdrik P, Padmanabhan P, Gulyás B, Szigeti K, Máthé D.
Published in: Plos One, 2022, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0264554

Psoriatic Resolved Skin Epidermal Keratinocytes Retain Disease-Residual Transcriptomic and Epigenomic Profiles.

Author(s): Ghaffarinia A, Ayaydin F, Póliska S, Manczinger M, Bolla BS, Flink LB, Balogh F, Veréb Z, Bozó R, Szabó K, Bata-Csörgő Z, Kemény L.
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24054556

Engineered Cas9 extracellular vesicles as a novel gene editing tool.

Author(s): Osteikoetxea X, Silva A, Lázaro-Ibáñez E, Salmond N, Shatnyeva O, Stein J, Schick J, Wren S, Lindgren J, Firth M, Madsen A, Mayr LM, Overman R, Davies R, Dekker N.
Published in: Extracell Vesicles, 2022, ISSN 2001-3078
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jev2.12225

Non-coding Natural Antisense Transcripts: Analysis and Application

Author(s): Julian C. Krappinger, Lilli Bonstingl, Katrin Pansy, Katja Sallinger, Nick I. Wreglesworth, Lukas Grinninger, Alexander Deutsch, Amin El-Heliebi, Thomas Kroneis, Ramsay J. Mcfarlane, Christoph W. Sensen, Julia Feichtinger
Published in: Journal of Biotechnology, 2021, ISSN 0168-1656
Publisher: Elsevier BV
DOI: 10.1016/j.jbiotec.2021.08.005

Optimization of CFTR gating through the evolution of its extracellular loops.

Author(s): Simon MA, Csanády L.
Published in: Journal of General Physiology, 2023, ISSN 0022-1295
Publisher: Rockefeller University Press
DOI: 10.1085/jgp.202213264

Circulating cardiomyocyte-derived extracellular vesicles reflect cardiac injury during systemic inflammatory response syndrome in mice.

Author(s): Hegyesi H, Pallinger É, Mecsei S, Hornyák B, Kovácsházi C, Brenner GB, Giricz Z, Pálóczi K, Kittel Á, Tóvári J, Turiak L, Khamari D, Ferdinandy P, Buzás EI.
Published in: Cellular and Molecular Life Sciences, 2022, ISSN 1431-1941
Publisher: Springer Nature
DOI: 10.1007/s00018-021-04125-w

Small paraquat resistance proteins modulate paraquat and ABA responses and confer drought tolerance to overexpressing Arabidopsis plants.

Author(s): Faragó D, Zsigmond L, Benyó D, Alcazar R, Rigó G, Ayaydin F, Rabilu SA, Hunyadi-Gulyás É, Szabados L
Published in: Plant, Cell and Environment, 2022, ISSN 0140-7791
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/pce.14338

Heavy metals in cigarette smoke strongly inhibit pancreatic ductal function and promote development of chronic pancreatitis

Author(s): Petra Pallagi, Emese Tóth, Marietta Görög, Viktória Venglovecz, Tamara Madácsy, Árpád Varga, Tünde Molnár, Noémi Papp, Viktória Szabó, Enikő Kúthy‐Sutus, Réka Molnár, Attila Ördög, Katalin Borka, Andrea Schnúr, Albert Kéri, Gyula Kajner, Kata Csekő, Emese Ritter, Dezső Csupor, Zsuzsanna Helyes, Gábor Galbács, Andrea Szentesi, László Czakó, Zoltán Rakonczay, Tamás Tak
Published in: Clinical and Translational Medicine, Issue 14, 2024, ISSN 2001-1326
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/ctm2.1733

Widespread alterations in microRNA biogenesis in human Huntington's disease putamen.

Author(s): Petry S, Keraudren R, Nateghi B, Loiselle A, Pircs K, Jakobsson J, Sephton C, Langlois M, St-Amour I, Hébert SS.
Published in: Acta neuropathologica communications, 2022, ISSN 2051-5960
Publisher: BioMed Central
DOI: 10.1186/s40478-022-01407-7

Predictive Potential of RNA Polymerase B (II) Subunit 1 (RPB1) Cytoplasmic Aggregation for Neoadjuvant Chemotherapy Failure.

Author(s): Nagy-Mikó B, Németh-Szatmári O, Faragó-Mészáros R, Csókási A, Bognár B, Ördög N, Borsos BN, Majoros H, Ujfaludi Z, Oláh-Németh O, Nikolényi A, Dobi Á, Kószó R, Sántha D, Lázár G, Simonka Z, Paszt A, Ormándi K, Pankotai T, Boros IM, Villányi Z, Vörös A.
Published in: International Journel of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242115869

Limited Evolutionary Conservation of the Phenotypic Effects of Antibiotic Resistance Mutations

Author(s): Gábor Apjok, Gábor Boross, Ákos Nyerges, Gergely Fekete, Viktória Lázár, Balázs Papp, Csaba Pál, Bálint Csörgő
Published in: Molecular Biology and Evolution, Issue 36/8, 2019, Page(s) 1601-1611, ISSN 0737-4038
Publisher: Oxford University Press
DOI: 10.1093/molbev/msz109

Genetic Characterization of Primary Mediastinal B-Cell Lymphoma: Pathogenesis and Patient Outcomes.

Author(s): Noerenberg D, Briest F, Hennch C, Yoshida K, Hablesreiter R, Takeuchi Y, Ueno H, Staiger AM, Ziepert M, Asmar F, Locher BN, Toth E, Weber T, Amini RM, Klapper W, Bouzani M, Poeschel V, Rosenwald A, Held G, Campo E, Ishaque N, Stamatopoulos K, Kanellis G, Anagnostopoulos I, Bullinger L, Goldschmidt N, Zinzani PL, Bödör C, Rosenquist R, Vassilakopoulos TP, Ott G, Ogawa S, Damm F.
Published in: Journal of Clinical Oncology, 2023, ISSN 1527-7755
Publisher: Lippincott Williams and Wilkins Ltd.
DOI: 10.1200/jco.23.01053

Identifying Suitable Reference Gene Candidates for Quantification of DNA Damage-Induced Cellular Responses in Human U2OS Cell Culture System.

Author(s): Barta N, Ördög N, Pantazi V, Berzsenyi I, Borsos BN, Majoros H, Páhi ZG, Ujfaludi Z, Pankotai T.
Published in: Biomolecules, 2023, ISSN 2218-273X
Publisher: MDPI
DOI: 10.3390/biom13101523

Profiling of Copy Number Alterations Using Low-Coverage Whole-Genome Sequencing Informs Differential Diagnosis and Prognosis in Primary Cutaneous Follicle Center Lymphoma.

Author(s): Bátai, B., Kiss, L., Varga, L., Nagy, Á., Househam, J., Baker, A. M., László, T., Udvari, A., Horváth, R., Nagy, T., Csomor, J., Szakonyi, J., Schneider, T., Graham, T. A., Alpár, D., Fitzgibbon, J., Szepesi, Á., & Bödör, C.
Published in: Modern pathology, 2024, ISSN 0893-3952
Publisher: Nature Publishing Group
DOI: 10.1016/j.modpat.2024.100465

Identification of an NF1 Microdeletion with Optical Genome Mapping.

Author(s): Büki G, Bekő A, Bödör C, Urbán P, Németh K, Hadzsiev K, Fekete G, Kehrer-Sawatzki H, Bene J.
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms241713580

Are the Cutaneous Microbiota a Guardian of the Skin's Physical Barrier? The Intricate Relationship between Skin Microbes and Barrier Integrity.

Author(s): Szabó K, Bolla BS, Erdei L, Balogh F, Kemény L.
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242115962

Characterization of the CDAA Diet-Induced Non-alcoholic Steatohepatitis Model: Sex-Specific Differences in Inflammation, Fibrosis, and Cholesterol Metabolism in Middle-Aged Mice

Author(s): Dániel Kucsera, Viktória E. Tóth, Dorottya Gergő, Imre Vörös, Zsófia Onódi, Anikó Görbe, Péter Ferdinandy, Zoltán V. Varga
Published in: Frontiers in Physiology, Issue 12, 2021, ISSN 1664-042X
Publisher: Frontiers Research Foundation
DOI: 10.3389/fphys.2021.609465

Physical prehabilitation improves the postoperative outcome of associating liver partition and portal vein ligation for staged hepatectomy in experimental model.

Author(s): Daradics N, Levay K, Horvath I, Kovacs N, Mathe D, Szigeti K, Szijarto A, Fulop A.
Published in: Scientific reports, Issue 20452322, 2022, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-23744-2

Molecular Network Approach Reveals Rictor as a Central Target of Cardiac ProtectomiRs

Author(s): András Makkos, Bence Ágg, Zoltán V. Varga, Zoltán Giricz, Mariann Gyöngyösi, Dominika Lukovic, Rainer Schulz, Monika Barteková, Anikó Görbe, Péter Ferdinandy
Published in: International Journal of Molecular Sciences, Issue 22/17, 2021, Page(s) 9539, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22179539

Image-based and machine learning-guided multiplexed serology test for SARS-CoV-2.

Author(s): Pietiäinen V, Polso M, Migh E, Guckelsberger C, Harmati M, Diosdi A, Turunen L, Hassinen A, Potdar S, Koponen A, Sebestyen EG, Kovacs F, Kriston A, Hollandi R, Burian K, Terhes G, Visnyovszki A, Fodor E, Lacza Z, Kantele A, Kolehmainen P, Kakkola L, Strandin T, Levanov L, Kallioniemi O, Kemeny L, Julkunen I, Vapalahti O, Buzas K, Paavolainen L, Horvath P, Hepojoki J.
Published in: Cell Report Methods, 2023, ISSN 2667-2375
Publisher: Cell Press
DOI: 10.1016/j.crmeth.2023.100565

Transcriptional Analysis-Based Alterations Affecting Neuritogenesis of the Peripheral Nervous System in Psoriasis

Author(s): Romhányi D, Szabó K, Kemény L, Sebestyén E, Groma G.
Published in: MDPI Life, 2022, ISSN 2075-1729
Publisher: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/life12010111

Activated polymorphonuclear derived extracellular vesicles are potential biomarkers of periprosthetic joint infection.

Author(s): • Sallai I, Marton N, Szatmári A, Kittel Á, Nagy G, Buzás EI, Khamari D, Komlósi Z, Kristóf K, Drahos L, Turiák L, Sugár S, Veres DS, Kendoff D, Zahár Á, Skaliczki G.
Published in: Public Library of Science, 2022, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0268076

Correlations Between the Expression of Stromal Cell Activation Related Biomarkers, L-NGFR, Phospho-ERK1-2 and CXCL12, and Primary Myelofibrosis Progression.

Author(s): Szekely T, Krenacs T, Maros ME, Bodor C, Daubner V, Csizmadia A, Vrabely B, Timar B.
Published in: Pathology&Oncology Research, 2022, ISSN 1219-4956
Publisher: Springer Verlag
DOI: 10.3389/pore.2022.1610217

Three-dimensional bioprinting of functional β-islet-like constructs.

Author(s): Parvaneh S, Kemény L, Ghaffarinia A, Yarani R, Veréb Z.
Published in: International Journal of Bioprinting, 2023, ISSN 2424-8002
Publisher: Whioce Publishing Pte. Ltd
DOI: 10.18063/ijb.v9i2.665

Oscillotherapeutics – Time-targeted interventions in epilepsy and beyond

Author(s): Yuichi Takeuchi, Antal Berényi
Published in: Neuroscience Research, Issue 152, 2020, Page(s) 87-107, ISSN 0168-0102
Publisher: Elsevier BV
DOI: 10.1016/j.neures.2020.01.002

Brain-derived neurotrophic factor increases cell number of neural progenitor cells derived from human induced pluripotent stem cells

Author(s): Panetha Pansri, Phetcharat Phanthong, Nopparat Suthprasertporn, Yindee Kitiyanant, Alisa Tubsuwan, Andras Dinnyes, Julianna Kobolak, Narisorn Kitiyanant
Published in: PeerJ, Issue 9, 2021, Page(s) e11388, ISSN 2167-8359
Publisher: PeerJ
DOI: 10.7717/peerj.11388

Hunting Out the autophagic problem in Huntington disease.

Author(s): Pircs K, Barker RA, Jakobsson J.
Published in: Autophagy, 2022, ISSN 1554-8627
Publisher: Landes Bioscience
DOI: 10.1080/15548627.2022.2069438

A journey to your self: The vague definition of immune self and its practical implications

Author(s): Balázs Koncz, Gergő Mihály Balogh, Máté Manczinger
Published in: Proceedings of the National Academy of Sciences, Issue 121, 2024, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2309674121

Stress-Related Regulation Is Abnormal in the Psoriatic Uninvolved Skin

Author(s): Renáta Bozó, Judit Danis, Lili Borbála Flink, Dániel László Vidács, Lajos Kemény, Zsuzsanna Bata-Csörgő
Published in: Life, Issue 11/7, 2021, Page(s) 599, ISSN 2075-1729
Publisher: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/life11070599

Establishment and characterization of a novel human induced pluripotent stem cell line stably expressing the iRFP720 reporter.

Author(s): Fehér A, Schnúr A, Muenthaisong S, Bellák T, Ayaydin F, Várady G, Kemter E, Wolf E, Dinnyés A.
Published in: Scientific Reports, 2022, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-12956-1

Systematic review and network analysis of microRNAs involved in cardioprotection against myocardial ischemia/reperfusion injury and infarction: Involvement of redox signalling

Author(s): András Makkos, Bence Ágg, Balázs Petrovich, Zoltán V. Varga, Anikó Görbe, Péter Ferdinandy
Published in: Free Radical Biology and Medicine, Issue 172, 2021, Page(s) 237-251, ISSN 0891-5849
Publisher: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2021.04.034

SerpinB2 is involved in cellular response upon UV irradiation

Author(s): Hajnalka Majoros, Zsuzsanna Ujfaludi, Barbara Nikolett Borsos, Viktória Vivien Hudacsek, Zita Nagy, Frederic Coin, Krisztina Buzas, Ilona Kovács, Tamás Bíró, Imre Miklós Boros, Tibor Pankotai
Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-39073-w

Editorial: The Role of Nuclear Molecules in the Pathogenesis of Autoimmune Disease

Author(s): David S. Pisetsky, Reinhard Voll, Edit I. Buzas
Published in: Frontiers in Immunology, Issue 12, 2021, ISSN 1664-3224
Publisher: Frontiers Media S.A.
DOI: 10.3389/fimmu.2021.737923

Thiopurines impair the apical plasma membrane expression of CFTR in pancreatic ductal cells via RAC1 inhibition.

Author(s): Tél B, Papp N, Varga Á, Szabó V, Görög M, Susánszki P, Crul T, Kis A, Sendstad IH, Bagyánszki M, Bódi N, Hegyi P, Maléth J, Pallagi P.
Published in: Cellular and Molecular Life Sciences, 2023, ISSN 1420-682X
Publisher: Birkhauser Verlag
DOI: 10.1007/s00018-022-04662-y

Novel actionable ROS1::GIT2 fusion in non-Langerhans cell histiocytosis with central nervous system involvement.

Author(s): Bedics G, Csóka M, Reiniger L, Varga E, Liptai Z, Papp G, Bekő A, Cervi C, Bödör C, Scheich B.
Published in: Acta neuropathologica communications, Issue 20515960, 2022, ISSN 2051-5960
Publisher: BioMed Central
DOI: 10.1007/s00401-022-02520-6

Anti-PD-1 Therapy Does Not Influence Hearing Ability in the Most Sensitive Frequency Range, but Mitigates Outer Hair Cell Loss in the Basal Cochlear Region

Author(s): Judit Szepesy, Gabriella Miklós, János Farkas, Dániel Kucsera, Zoltán Giricz, Anita Gáborján, Gábor Polony, Ágnes Szirmai, László Tamás, László Köles, Zoltán V. Varga, Tibor Zelles
Published in: International Journal of Molecular Sciences, Issue 21/18, 2020, Page(s) 6701, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21186701

Revealing a Phenotypical Appearance of Ibrutinib Resistance in Patients With Chronic Lymphocytic Leukaemia by Flow Cytometry.

Author(s): Takács F, Kotmayer L, Czeti Á, Szalóki G, László T, Mikala G, Márk Á, Masszi A, Farkas P, Plander M, Weisinger J, Demeter J, Fekete S, Szerafin L, Deák BM, Szaleczky E, Sulák A, Borbényi Z, Barna G.
Published in: Pathology and Oncology Research, Issue 15322807, 2022, ISSN 1532-2807
Publisher: Frontiers Media S.A.
DOI: 10.3389/pore.2022.1610659

Fluorescent, Prussian Blue-Based Biocompatible Nanoparticle System for Multimodal Imaging Contrast

Author(s): László Forgách, Nikolett Hegedűs, Ildikó Horváth, Bálint Kiss, Noémi Kovács, Zoltán Varga, Géza Jakab, Tibor Kovács, Parasuraman Padmanabhan, Krisztián Szigeti, Domokos Máthé
Published in: Nanomaterials, Issue 10/9, 2020, Page(s) 1732, ISSN 2079-4991
Publisher: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/nano10091732

Simple binding of protein kinase A prior to phosphorylation allows CFTR anion channels to be opened by nucleotides

Author(s): Csaba Mihályi, Iordan Iordanov, Beáta Töröcsik, László Csanády
Published in: Proceedings of the National Academy of Sciences, Issue 117/35, 2020, Page(s) 21740-21746, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2007910117

PersonALL: a genetic scoring guide for personalized risk assessment in pediatric B-cell precursor acute lymphoblastic leukemia.

Author(s): Kelemen Á, Sebestyén E, Jakab Z, Matolcsy A, Kiss C, Kovács G, Savola S, Bödör C, Alpár D.
Published in: British Journal of Cancer, 2023, ISSN 1532-1827
Publisher: Nature Publishing Group
DOI: 10.1038/s41416-023-02309-8

Extracellular vesicles promote migration despite BRAF inhibitor treatment in malignant melanoma cells

Author(s): Afrodité Németh, Gréta L. Bányai, Nikolett K. Dobos, Tamás Kós, Anikó Gaál, Zoltán Varga, Edit I. Buzás, Delaram Khamari, Magdolna Dank, István Takács, A. Marcell Szász, Tamás Garay
Published in: Cell Communication and Signaling, Issue 22, 2024, ISSN 1478-811X
Publisher: BioMed Central
DOI: 10.1186/s12964-024-01660-4

Olive Oil Improves While Trans Fatty Acids Further Aggravate the Hypomethylation of LINE-1 Retrotransposon DNA in an Environmental Carcinogen Model. Nutrients.

Author(s): Szabo L, Molnar R, Tomesz A, Deutsch A, Darago R, Varjas T, Ritter Z, Szentpeteri JL, Andreidesz K, Mathe D, Hegedüs I, Sik A, Budan F, Kiss I.
Published in: Nutrients, 2022, ISSN 2072-6643
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu14040908

Wnt Activity and Cell Proliferation Are Coupled to Extracellular Vesicle Release in Multiple Organoid Models

Author(s): Gyöngyvér Orsolya Sándor, András Áron Soós, Péter Lörincz, Lívia Rojkó, Tünde Harkó, Levente Bogyó, Tamás Tölgyes, Attila Bursics, Edit I. Buzás, Judit Moldvay, Zoltán Wiener
Published in: Frontiers in Cell and Developmental Biology, Issue 9, 2021, ISSN 2296-634X
Publisher: Frontiers Media S.A.
DOI: 10.3389/fcell.2021.670825

Questioning Glutamate Excitotoxicity in Acute Brain Damage: The Importance of Spreading Depolarization. Neurocrit Care.

Author(s): Andrew RD, Farkas E, Hartings JA, Brennan KC, Herreras O, Müller M, Kirov SA, Ayata C, Ollen-Bittle N, Reiffurth C, Revah O, Robertson RM, Dawson-Scully KD, Ullah G, Dreier JP.
Published in: Neurocritical care, 2022, ISSN 1556-0961
Publisher: Springer Nature
DOI: 10.1007/s12028-021-01429-4

Alzheimer’s Disease: A Molecular View of β-Amyloid Induced Morbific Events

Author(s): Rajmohamed Mohamed Asik, Natarajan Suganthy, Mohamed Asik Aarifa, Arvind Kumar, Krisztián Szigeti, Domokos Mathe, Balázs Gulyás, Govindaraju Archunan, Parasuraman Padmanabhan
Published in: Biomedicines, Issue 9/9, 2021, Page(s) 1126, ISSN 2227-9059
Publisher: MDPI AG
DOI: 10.3390/biomedicines9091126

"Unraveling Transcriptome Profile, Epigenetic Dynamics, and Morphological Changes in Psoriasis-like Keratinocytes: ""Insights into Similarity with Psoriatic Lesional Epidermis"""

Author(s): Ghaffarinia A, Póliska S, Ayaydin F, Goblos A, Parvaneh S, Manczinger M, Balogh F, Erdei L, Veréb Z, Szabó K, Bata-Csörgő Z, Kemény L.
Published in: Cells, 2023, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells12242825

Altered Cellular Protein Quality Control System Modulates Cardiomyocyte Function in Volume Overload-Induced Hypertrophy.

Author(s): Gömöri K, Herwig M, Hassoun R, Budde H, Mostafi N, Delalat S, Modi S, Begovic M, Szabados T, Pipis J, Farkas-Morvay N, Leprán I, Kovács Á, Mügge A, Ferdinandy P, Görbe A, Bencsik P, Hamdani N.
Published in: Atioxidants, Issue 20763921, 2022, ISSN 2076-3921
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/antiox11112210

Delayed Contralateral Nephrectomy Halted Post-Ischemic Renal Fibrosis Progression and Inhibited the Ischemia-Induced Fibromir Upregulation in Mice

Author(s): Beáta Róka, Pál Tod, Tamás Kaucsár, Éva Nóra Bukosza, Imre Vörös, Zoltán V. Varga, Balázs Petrovich, Bence Ágg, Péter Ferdinandy, Gábor Szénási, Péter Hamar
Published in: Biomedicines, Issue 9/7, 2021, Page(s) 815, ISSN 2227-9059
Publisher: MDPI AG
DOI: 10.3390/biomedicines9070815

Degenerate but indispensable: how CFTR channel activity depends on the catalytically inactive ATP binding site?

Author(s): László Csanády
Published in: The Journal of Physiology, 2021, ISSN 0022-3751
Publisher: Blackwell Publishing Inc.
DOI: 10.1113/jp282278

Transient Hypoperfusion to Ischemic/Anoxic Spreading Depolarization is Related to Autoregulatory Failure in the Rat Cerebral Cortex

Author(s): Menyhárt Á, Varga DP, M Tóth O, Makra P, Bari F, Farkas E.
Published in: Transient Hypoperfusion to Ischemic/Anoxic Spreading Depolarization is Related to Autoregulatory Failure in the Rat Cerebral Cortex., 2021, ISSN 1556-0961
Publisher: Springer Nature
DOI: 10.1007/s12028-021-01393-z

Stellaria media tea protects against diabetes-induced cardiac dysfunction in rats without affecting glucose tolerance.

Author(s): Demján V, Sója A, Kiss T, Fejes A, Gausz D, Szűcs G, Siska A, Földesi I, Tengölics R, Darula Zs, Csupor D, Pipicz M, Csont T.
Published in: JTCM Journal of Traditional and Complementary Medicine, 2021, ISSN 2225-4110
Publisher: Medknow Publications and Media Pvt. Ltd
DOI: 10.1016/j.jtcme.2021.08.003

The roles of extracellular vesicles in the immune system.

Author(s): Buzas EI.
Published in: Nature Reviews Immunology, 2022, ISSN 1474-1733
Publisher: Nature Publishing Group
DOI: 10.1038/s41577-022-00763-8

Interplay of Oxidative Stress and Necrosis-like Cell Death in Cardiac Ischemia/Reperfusion Injury: A Focus on Necroptosis.

Author(s): Adameova A, Horvath C, Abdul-Ghani S, Varga ZV, Suleiman MS, Dhalla NS.
Published in: Biomedicines, 2022, ISSN 2227-9059
Publisher: MDPI AG
DOI: 10.3390/biomedicines10010127

Proteotranscriptomic Discrimination of Tumor and Normal Tissues in Renal Cell Carcinoma.

Author(s): Bartha Á, Darula Z, Munkácsy G, Klement É, Nyirády P, Győrffy B.
Published in: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24054488

Volatile anaesthetics inhibit the thermosensitive nociceptor ion channel transient receptor potential melastatin 3 (TRPM3)

Author(s): Balázs Kelemen, Erika Lisztes, Anita Vladár, Martin Hanyicska, János Almássy, Attila Oláh, Attila Gábor Szöllősi, Zsófia Pénzes, János Posta, Thomas Voets, Tamás Bíró, Balázs István Tóth
Published in: Biochemical Pharmacology, Issue 174, 2020, Page(s) 113826, ISSN 0006-2952
Publisher: Elsevier BV
DOI: 10.1016/j.bcp.2020.113826

Bicarbonate Evokes Reciprocal Changes in Intracellular Cyclic di-GMP and Cyclic AMP Levels in Pseudomonas aeruginosa

Author(s): Kasidid Ruksakiet, Balázs Stercz, Gergő Tóth, Pongsiri Jaikumpun, Ilona Gróf, Roland Tengölics, Zsolt M. Lohinai, Péter Horváth, Mária A. Deli, Martin C. Steward, Orsolya Dobay, Ákos Zsembery
Published in: Biology, Issue 10/6, 2021, Page(s) 519, ISSN 2079-7737
Publisher: MDPI
DOI: 10.3390/biology10060519

Shared extracellular vesicle miRNA profiles of matched ductal pancreatic adenocarcinoma organoids and blood plasma samples show the power of organoid technology

Author(s): Anikó Zeöld, Gyöngyvér Orsolya Sándor, Anna Kiss, András Áron Soós, Tamás Tölgyes, Attila Bursics, Ákos Szűcs, László Harsányi, Ágnes Kittel, András Gézsi, Edit I. Buzás, Zoltán Wiener
Published in: Cellular and Molecular Life Sciences, 2020, ISSN 1420-682X
Publisher: Birkhauser Verlag
DOI: 10.1007/s00018-020-03703-8

The IV International Symposium on Fungal Stress and the XIII International Fungal Biology Conference.

Author(s): Alder-Rangel A, Bailão AM, Herrera-Estrella A, Rangel AEA, Gácser A, Gasch AP, Campos CBL, Peters C, Camelim F, Verde F, Gadd GM, Braus G, Eisermann I, Quinn J, Latgé JP, Aguirre J, Bennett JW, Heitman J, Nosanchuk JD, Partida-Martínez LP, Bassilana M, Acheampong MA, Riquelme M, Feldbrügge M, Keller NP, Keyhani NO, Gunde-Cimerman N, Nascimento R, Arkowitz RA, Mouriño-Pérez RR, Naz SA, Avery
Published in: Fungal Biology, 2023, ISSN 1096-0937
Publisher: Academic Press Inc.
DOI: 10.1016/j.funbio.2023.04.006

Estimating the true stability of the prehydrolytic outward-facing state in an ABC protein.

Author(s): Simon MA, Iordanov I, Szollosi A, Csanády L.
Published in: eLife, 2023, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.90736

Merkel K, Szöllősi D, Horváth I, Jezsó B, Baranyai Z, Szigeti K, Varga Z, Hegedüs I, Padmanabhan P, Gulyás B, Bergmann R, Máthé D.

Author(s): Radiolabeling of Platelets with 99mTc-HYNIC-Duramycin for In Vivo Imaging Studies.
Published in: Internaitonal Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242317119

The Rad5 helicase and RING domains contribute to genome stability through their independent catalytic activities.

Author(s): Toth R, Balogh D, Pinter L, Jaksa G, Szeplaki B, Graf A, Gyorfy Z, Zs Enyedi M, Kiss E, Haracska L, Unk I.
Published in: Journal of molecular biology, 2022, ISSN 0022-2836
Publisher: Academic Press
DOI: 10.1016/j.jmb.2021.167437

IL-1β neutralization prevents diastolic dysfunction development, but lacks hepatoprotective effect in an aged mouse model of NASH.

Author(s): Kucsera D, Tóth VE, Sayour NV, Kovács T, Gergely TG, Ruppert M, Radovits T, Fábián A, Kovács A, Merkely B, Ferdinandy P, Varga ZV.
Published in: Scientific Reports, 2023, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-26896-3

Characterization of Neurons Expressing the Novel Analgesic Drug Target Somatostatin Receptor 4 in Mouse and Human Brains

Author(s): Angéla Kecskés, Krisztina Pohóczky, Miklós Kecskés, Zoltán V. Varga, Viktória Kormos, Éva Szőke, Nóra Henn-Mike, Máté Fehér, József Kun, Attila Gyenesei, Éva Renner, Miklós Palkovits, Péter Ferdinandy, István M. Ábrahám, Balázs Gaszner, Zsuzsanna Helyes
Published in: International Journal of Molecular Sciences, Issue 21/20, 2020, Page(s) 7788, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21207788

Interdisciplinary Analyses of Bronze Age Communities from Western Hungary Reveal Complex Population Histories.

Author(s): Gerber D, Szeifert B, Székely O, Egyed B, Gyuris B, Giblin JI, Horváth A, Köhler K, Kulcsár G, Kustár Á, Major I, Molnár M, Palcsu L, Szeverényi V, Fábián S, Mende BG, Bondár M, Ari E, Kiss V, Szécsényi-Nagy A.
Published in: Molecular Biology and Evolution, 2023, ISSN 1537-1719
Publisher: Oxford University Press
DOI: 10.1093/molbev/msad182

IDENTIFICATION OF NEGATIVE REGULATORS OF THE CUTIBACTERIUM ACNES-INDUCED INNATE IMMUNE ACTIVATION IN HUMAN EPIDERMAL KERATINOCYTES

Author(s): Lilla Erdei
Published in: 2020
Publisher: -

Immune-inflammatory targets in chronic heart failure: inflammasomes and the endocannabinoid system

Author(s): Zsófia Gulyás-Onódi
Published in: 2022
Publisher: Semmelweis University

Értekezés címe: Az in vivo fehérjeaggregáció útvonalait befolyásoló tényezők vizsgálata Escherichia coliban

Author(s): Györkei Ádám
Published in: 2022
Publisher: -

Discovery of small-molecule inhibitors of Rad6 function and the Rad6-Rad18 interaction

Author(s): Sharma Gaurav
Published in: 2023
Publisher: -

A CFTR anioncsatorna extracelluláris régiójának a csatorna működésére gyakorolt hatása

Author(s): Simon Márton András
Published in: 2023
Publisher: -

Application of Circulating Tumor DNA Analysis for the Detection of EZH2 Mutations in Follicular Lymphoma

Author(s): Nagy Ákos
Published in: 2023
Publisher: -

BRCA1/2 patogén és ismeretlen klinikai szignifikanciájú variánsok azonosítása és vizsgálati lehetőségei

Author(s): Gráf Alexandra
Published in: 2022
Publisher: -

The study of the membrane microdomain localization of the prion-family proteins, prion and Shadoo and their interaction with calnexin

Author(s): Divya Teja Dondapati
Published in: 2022
Publisher: University of Szeged

Hipertermia-okozta stresszválasz molekuláris mechanizmusai emlős sejtekben

Author(s): Tiszlavicz Ádám
Published in: 2022
Publisher: -

Compensatory evolution as a driver of morphological novelties

Author(s): Sarkadi Zsuzsa
Published in: 2022
Publisher: -

Antitumor effects of modulated electro-hyperthermia in 4T1 triple-negative breast cancer models

Author(s): Danics Lea Orsolya
Published in: 2021
Publisher: -

Controlling cell polarity in human pancreatic organoids significantly improves the resolution of ex vivo physiological modeling

Author(s): Varga Árpád
Published in: 2023
Publisher: -

Epigenetic consequences of in utero exposure to rosuvastatin include altered histone methylation patterns in newborn rat brains

Author(s): Fábián-Dulka Karolina
Published in: 2021
Publisher: University of Szeged

Molecular background of resistance to targeted therapies in chronic lymphocytic

Author(s): Kotmayer Lili Eszter
Published in: 2023
Publisher: -

Potential relevance of altered cartilage oligomeric matrix protein in psoriasis

Author(s): Renáta Bozó
Published in: 2020
Publisher: University of Szeged

Discovery of small-molecule inhibitors of Uba1 and development of step-specific assays for PCNA ubiquitination

Author(s): Paras Gaur
Published in: 2020
Publisher: -

A funkcionális metagenomika módszerének kiterjesztése kórokozó baktériumokra az antibiotikumrezisztencia vizsgálatának céljából

Author(s): Számel Mónika
Published in: 2023
Publisher: -

CFTR deficiency causes PMCA4 dysfunction, intracellular Ca2+ elevation and promotes epithelial cell damage in alcoholic pancreatitis and hepatitis

Author(s): Tamara Éva Madácsy
Published in: 2022
Publisher: University of Szeged

Vasculitides primarily involving the skin

Author(s): Géza Róbert Nagy
Published in: 2020
Publisher: University of Szeged

RAD18-dependent Activation of FAN1 by Ub-PCNA to Rescue DNA Interstrand crosslinks along with TLS Pol η

Author(s): Qiuzhen Li
Published in: 2021
Publisher: -

Bioanalytics, lipidomics and metabolomics application of one- and two-dimensional LC-MS techniques

Author(s): Tímea Körmöczi
Published in: 2022
Publisher: University of Szeged

The effect of Cutibacterium acnes on the barrier properties of in vitro cultured keratinocytes

Author(s): Beáta Szilvia Bolla
Published in: 2020
Publisher: University of Szeged

Szívelégtelenségben ható szerek

Author(s): Ferdinandy Péter, Varga Zoltán In: Gyires Klára, Fürst Zsuzsanna, Ferdinandy Péter, Pintér Erika, Szilvássy Zoltán, Varró András (szerk.)
Published in: Farmakológia és klinikai farmakológia: egyetemi tankönyv, Issue p. 10, 2020, Page(s) pp. 224-233
Publisher: Medicina Könyvkiadó Zrt.

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