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Establishing the Hungarian Center of Excellence for Molecular Medicine in partnership with EMBL

Publications

Detection and Functional Evaluation of the P2X7 Receptor in hiPSC Derived Neurons and Microglia-Like Cells. Front Mol Neurosci

Auteurs: Francistiová L, Vörös K, Lovász Z, Dinnyés A, Kobolák J.
Publié dans: Frontiers in molecular neuroscience, 2022, ISSN 1662-5099
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fnmol.2021.793769

Regulation of Orai channels by intracellular pH: one step closer to understand CRAC channel biology? J Physiol.

Auteurs: Maléth J.
Publié dans: Journal of Physiology, 2022, ISSN 1469-7793
Éditeur: Wiley-Blackwell Publishing Ltd
DOI: 10.1113/jp282680

Sierra RO, Pedraza LK, Barcsai L, Pejin A, Li Q, Kozák G, Takeuchi Y, Nagy AJ, Lőrincz ML, Devinsky O, Buzsáki G, Berényi A.

Auteurs: Closed-loop brain stimulation augments fear extinction in male rats. Nat Commun.
Publié dans: Nature Communications, 2023, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-023-39546-7

Phenotypic plasticity of melanocytes derived from human adult skin

Auteurs: Dániel László Vidács, Zoltán Veréb, Renáta Bozó, Lili Borbála Flink, Hilda Polyánka, István Balázs Németh, Szilárd Póliska, Benjamin Tamás Papp, Máté Manczinger, Róbert Gáspár, Seyedmohsen Mirdamadi, Lajos Kemény, Zsuzsanna Bata‐Csörgő
Publié dans: Pigment Cell & Melanoma Research, 2021, ISSN 1755-1471
Éditeur: Basil Blackwell
DOI: 10.1111/pcmr.13012

Next-Generation Sequencing-Based Genomic Profiling of Children with Acute Myeloid Leukemia.

Auteurs: Krizsán S, Péterffy B, Egyed B, Nagy T, Sebestyén E, Hegyi LL, Jakab Z, Erdélyi DJ, Müller J, Péter G, Csanádi K, Kállay K, Kriván G, Barna G, Bedics G, Haltrich I, Ottóffy G, Csernus K, Vojcek Á, Tiszlavicz LG, Gábor KM, Kelemen Á, Hauser P, Gaál Z, Szegedi I, Ujfalusi A, Kajtár B, Kiss C, Matolcsy A, Tímár B, Kovács G, Alpár D, Bödör C.
Publié dans: Journal of Molecular Diagnostics, 2023, ISSN 1525-1578
Éditeur: American Society for Investigative Pathology
DOI: 10.1016/j.jmoldx.2023.04.004

Herpes Simplex Virus Infection Alters the Immunological Properties of Adipose-Tissue-Derived Mesenchymal-Stem Cells.

Auteurs: Kun-Varga A, Gubán B, Miklós V, Parvaneh S, Guba M, Szűcs D, Monostori T, Varga J, Varga Á, Rázga Z, Bata-Csörgő Z, Kemény L, Megyeri K, Veréb Z.
Publié dans: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms241511989

Candida albicans Enhances the Progression of Oral Squamous Cell Carcinoma In Vitro and In Vivo.

Auteurs: Vadovics M, Ho J, Igaz N, Alföldi R, Rakk D, Veres É, Szücs B, Horváth M, Tóth R, Szücs A, Csibi A, Horváth P, Tiszlavicz L, Vágvölgyi C, Nosanchuk JD, Szekeres A, Kiricsi M, Henley-Smith R, Moyes DL, Thavaraj S, Brown R, Puskás LG, Naglik JR, Gácser A.
Publié dans: mBio, 2022, ISSN 2150-7511
Éditeur: American Society for Microbiology
DOI: 10.1128/mbio.03144-21

Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY.

Auteurs: Mansouri L, Thorvaldsdottir B, Sutton LA, Karakatsoulis G, Meggendorfer M, Parker H, Nadeu F, Brieghel C, Laidou S, Moia R, Rossi D, Catherwood M, Kotaskova J, Delgado J, Rodríguez-Vicente AE, Benito R, Rigolin GM, Bonfiglio S, Scarfo L, Mattsson M, Davis Z, Gogia A, Rani L, Baliakas P, Foroughi-Asl H, Jylhä C, Skaftason A, Rapado I, Miras F, Martinez-Lopez J, de la Serna J, Rivas JMH, Thornton
Publié dans: Leukemia, 2022, ISSN 0887-6924
Éditeur: Nature Publishing Group
DOI: 10.1038/s41375-022-01802-y

Characterization and functional analysis of zinc trafficking in the human fungal pathogen Candida parapsilosis.

Auteurs: Takács T, Németh MT, Bohner F, Vágvölgyi C, Jankovics F, Wilson D, Gácser A.
Publié dans: Open biology, 2022, ISSN 2046-2441
Éditeur: Royal Society Publishing
DOI: 10.1098/rsob.220077

Molecular pathology of the R117H cystic fibrosis mutation is explained by loss of a hydrogen bond.

Auteurs: Simon MA, Csanády L.
Publié dans: eLife Sciences Publications, 2019, ISSN 2050-084X
Éditeur: eLife Sciences Publications
DOI: 10.7554/elife.74693

Influence of cardiometabolic comorbidities on myocardial function, infarction, and CARDIOPROTECTION: Role of cardiac redox signaling

Auteurs: Ioanna Andreadou, Andreas Daiber, Gary F. Baxter, Maria.Felice Brizzi, Fabio di Lisa, Nina Kaludercic, Antigone Lazou, Zoltán.V. Varga, Coert Zuurbier, Rainer Schulz, Péter Ferdinandy
Publié dans: Free Radical Biology and Medicine, 2021, ISSN 0891-5849
Éditeur: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2021.02.012

Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes.

Auteurs: Rönn T, Ofori JK, Perfilyev A, Hamilton A, Pircs K, Eichelmann F, Garcia-Calzon S, Karagiannopoulos A, Stenlund H, Wendt A, Volkov P, Schulze MB, Mulder H, Eliasson L, Ruhrmann S, Bacos K, Ling C.
Publié dans: Nature Communications, 2023, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-023-43719-9

Antineoplastic drugs inducing cardiac and vascular toxicity - An update.

Auteurs: Barachini S, Ghelardoni S, Varga ZV, Mehanna RA, Montt-Guevara MM, Ferdinandy P, Madonna R.
Publié dans: Vascular Pharmacology, 2023, ISSN 1879-3649
Éditeur: Elsevier
DOI: 10.1016/j.vph.2023.107223

The genomic landscape of teenage and young adult T‐cell acute lymphoblastic leukemia

Auteurs: Marcela B. Mansur, Caroline L. Furness, Sirintra Nakjang, Amir Enshaei, Donat Alpar, Sue M. Colman, Lynne Minto, Julie Irving, Beth V. Poole, Elda P. Noronha, Suvi Savola, Sameena Iqbal, John Gribben, Maria S. Pombo‐de‐Oliveira, Tony M. Ford, Mel F. Greaves, Frederik W. Delft
Publié dans: Cancer Medicine, 2021, ISSN 2045-7634
Éditeur: John Wiley and Sons Ltd
DOI: 10.1002/cam4.4024

Liquid biopsy-based monitoring of residual disease in multiple myeloma by analysis of the rearranged immunoglobulin genes-A feasibility study.

Auteurs: Marx A, Osváth M, Szikora B, Pipek O, Csabai I, Nagy Á, Bödör C, Matula Z, Nagy G, Bors A, Uher F, Mikala G, Vályi-Nagy I, Kacskovics I.
Publié dans: PLoS One, 2023, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0285696

In Vitro Determination of Inhibitory Effects of Humic Substances Complexing Zn and Se on SARS-CoV-2 Virus Replication. Foods.

Auteurs: Hajdrik P, Pályi B, Kis Z, Kovács N, Veres DS, Szigeti K, Budán F, Hegedüs I, Kovács T, Bergmann R, Máthé D.
Publié dans: Foods, 2022, ISSN 2304-8158
Éditeur: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/foods11050694

Beta-lactamase dependent and independent evolutionary paths to high-level ampicillin resistance

Auteurs: Rotem Gross, Idan Yelin, Viktória Lázár, Manoshi Sen Datta, Roy Kishony
Publié dans: Nature Communications, Numéro 15, 2024, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-024-49621-2

Synergism of red blood cells and tranexamic acid in the inhibition of fibrinolysis.

Auteurs: Raska A, Kálmán K, Egri B, Csikós P, Beinrohr L, Szabó L, Tenekedjiev K, Nikolova N, Longstaff C, Roberts I, Kolev K, Wohner N.
Publié dans: Journal of Thrombosis and Haemostasis, 2023, ISSN 1538-7836
Éditeur: Wiley-Blackwell Publishing Ltd
DOI: 10.1016/j.jtha.2023.11.009

TRAF3 and NBR1 both influence the effect of the disease‐causing CYLD(Arg936X) mutation on NF‐κB activity

Auteurs: Judit Danis, Evelyn Kelemen, Neil Rajan, Nikoletta Nagy, Márta Széll, Éva Ádám
Publié dans: Experimental Dermatology, 2021, ISSN 0906-6705
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/exd.14365

Capturing time-dependent activation of genes and stress-response pathways using transcriptomics in iPSC-derived renal proximal tubule cells.

Auteurs: Jennings P, Carta G, Singh P, da Costa Pereira D, Feher A, Dinnyes A, Exner TE, Wilmes A.
Publié dans: Cell Biology and Toxicology, 2022, ISSN 0742-2091
Éditeur: Kluwer Academic Publishers
DOI: 10.1007/s10565-022-09783-5

Blue flash sheds light on the roles of individual phosphoserines in CFTR channel activation.

Auteurs: Csanády L.
Publié dans: Journal of General Physiology, 2023, ISSN 0022-1295
Éditeur: Rockefeller University Press
DOI: 10.1085/jgp.202313336

Cellular and Molecular Effects of SARS-CoV-2 Linking Lung Infection to the Brain

Auteurs: Linda Francistiová, Adrián Klepe, Géza Curley, Károly Gulya, András Dinnyés, Kata Filkor
Publié dans: Frontiers in Immunology, Numéro 12, 2021, ISSN 1664-3224
Éditeur: Frontiers Media S.A.
DOI: 10.3389/fimmu.2021.730088

Extracellular Vesicle-Mediated Metastasis Suppressors NME1 and NME2 Modify Lipid Metabolism in Fibroblasts.

Auteurs: Mátyási B, Petővári G, Dankó T, Butz H, Likó I, Lőw P, Petit I, Bittar R, Bonnefont-Rousselot D, Farkas Z, Szeniczey T, Molnár K, Pálóczi K, Buzás EI, Boissan M, Sebestyén A, Takács-Vellai K.
Publié dans: Cancers, 2022, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14163913

Application of Lacunarity for Quantification of Single Molecule Localization Microscopy Images.

Auteurs: Kovács BBH, Varga D, Sebők D, Majoros H, Polanek R, Pankotai T, Hideghéty K, Kukovecz Á, Erdélyi M.
Publié dans: Cells, Numéro 20734409, 2022, ISSN 2073-4409
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cells11193105

AIM2-driven inflammasome activation in heart failure

Auteurs: Zsófia Onódi, Mihály Ruppert, Dániel Kucsera, Alex Ali Sayour, Viktória E Tóth, Gábor Koncsos, Julianna Novák, Gábor B Brenner, András Makkos, Tamás Baranyai, Zoltán Giricz, Anikó Görbe, Przemyslaw Leszek, Mariann Gyöngyösi, Iván G Horváth, Rainer Schulz, Béla Merkely, Péter Ferdinandy, Tamás Radovits, Zoltán V Varga
Publié dans: Cardiovascular Research, 2021, ISSN 0008-6363
Éditeur: Elsevier BV
DOI: 10.1093/cvr/cvab202

Suboptimal global transcriptional response increases the harmful effects of loss-of-function mutations

Auteurs: Károly Kovács, Zoltán Farkas, Djordje Bajić, Dorottya Kalapis, Andreea Daraba, Karola Almási, Bálint Kintses, Zoltán Bódi, Richard A Notebaart, Juan F Poyatos, Patrick Kemmeren, Frank C P Holstege, Csaba Pál, Balázs Papp
Publié dans: Molecular Biology and Evolution, 2020, ISSN 0737-4038
Éditeur: Oxford University Press
DOI: 10.1093/molbev/msaa280

Adenosine Promotes Human Hair Growth and Inhibits Catagen Transition In Vitro: Role of the Outer Root Sheath Keratinocytes

Auteurs: Erika Lisztes, Balázs István Tóth, Marta Bertolini, Imre Lőrinc Szabó, Nóra Zákány, Attila Oláh, Attila Gábor Szöllősi, Ralf Paus, Tamás Bíró
Publié dans: Journal of Investigative Dermatology, Numéro 140/5, 2020, Page(s) 1085-1088.e6, ISSN 0022-202X
Éditeur: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2019.08.456

The Phytocannabinoid (–)-Cannabidiol Operates as a Complex, Differential Modulator of Human Hair Growth: Anti-Inflammatory Submicromolar versus Hair Growth Inhibitory Micromolar Effects

Auteurs: Imre L. Szabó, Erika Lisztes, Gabriella Béke, Kinga Fanni Tóth, Ralf Paus, Attila Oláh, Tamás Bíró
Publié dans: Journal of Investigative Dermatology, Numéro 140/2, 2019, ISSN 0022-202X
Éditeur: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2019.07.690

Endoplasmin Is a Hypoxia-Inducible Endoplasmic Reticulum-Derived Cargo of Extracellular Vesicles Released by Cardiac Cell Lines.

Auteurs: Koncz A, Turiák L, Németh K, Lenzinger D, Bárkai T, Lőrincz P, Zelenyánszki H, Vukman KV, Buzás EI, Visnovitz T.
Publié dans: Membranes, 2023, ISSN 2077-0375
Éditeur: Molecular Diversity Preservation International
DOI: 10.3390/membranes13040431

Nanotheranostic agents for neurodegenerative diseases

Auteurs: Parasuraman Padmanabhan, Mathangi Palanivel, Ajay Kumar, Domokos Máthé, George K. Radda, Kah-Leong Lim, Balázs Gulyás
Publié dans: Emerging Topics in Life Sciences, Numéro 4/6, 2020, Page(s) 645-675, ISSN 2397-8554
Éditeur: Portland Press
DOI: 10.1042/etls20190141

Cyclooxygenase-2 Modulates Glycosaminoglycan Production in the Skin During Salt Overload

Auteurs: Róbert Agócs, Domonkos Pap, Dániel Sugár, Gábor Tóth, Lilla Turiák, Zoltán Veréb, Lajos Kemény, Tivadar Tulassay, Ádám Vannay, Attila J. Szabó
Publié dans: Frontiers in Physiology, Numéro 11, 2020, ISSN 1664-042X
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fphys.2020.561722

Coordinated Cut and Bypass: Replication of Interstrand Crosslink-Containing DNA

Auteurs: Qiuzhen Li, Kata Dudás, Gabriella Tick, Lajos Haracska
Publié dans: Frontiers in Cell and Developmental Biology, Numéro 9, 2021, ISSN 2296-634X
Éditeur: Frontiers Media S.A.
DOI: 10.3389/fcell.2021.699966

Manifestation of Triploid Heterosis in the Root System after Crossing Diploid and Autotetraploid Energy Willow Plants.

Auteurs: Dudits D, Cseri A, Török K, Vankova R, Dobrev PI, Sass L, Steinbach G, Kelemen-Valkony I, Zombori Z, Ferenc G, Ayaydin F.
Publié dans: Genes, 2023, ISSN 2073-4425
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes14101929

Cardioprotective efficacy of limb remote ischemic preconditioning in rats: discrepancy between meta-analysis and a three-centre in vivo study.

Auteurs: Sayour NV, Brenner GB, Makkos A, Kiss B, Kovácsházi C, Gergely TG, Aukrust SG, Tian H, Zenkl V, Gömöri K, Szabados T, Bencsik P, Heinen A, Schulz R, Baxter GF, Zuurbier CJ, Vokó Z, Ferdinandy P, Giricz Z.
Publié dans: Caridovascular Research, 2023, ISSN 0008-6363
Éditeur: Elsevier BV
DOI: 10.1093/cvr/cvad024

IBCL-222 Parallel Testing of Liquid Biopsy (ctDNA) and Tissue Biopsy Samples Yields Higher Frequency of EZH2 Mutations in Follicular Lymphoma.

Auteurs: Nagy Á, Bátai B, Gróf S, Kiss L, Balogh A, Mikala G, Király PA, Jóna Á, Demeter J, Masszi T, Masszi A, Schneider T, Bödör C.
Publié dans: Clin Lymphoma Myeloma Leuk., Numéro 21522650, 2022, ISSN 2152-2650
Éditeur: Cancer Media Group
DOI: 10.1016/s2152-2650(22)01553-1

BC-miR: Monitoring Breast Cancer-Related miRNA Profile in Blood Sera-A Prosperous Approach for Tumor Detection.

Auteurs: Borsos BN, Páhi ZG, Ujfaludi Z, Sükösd F, Nikolényi A, Bankó S, Pankotai-Bodó G, Oláh-Németh O, Pankotai T.
Publié dans: Cells, 2022, ISSN 2073-4409
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cells11172721

Extracellular Vesicle-Based Communication May Contribute to the Co-Evolution of Cancer Stem Cells and Cancer-Associated Fibroblasts in Anti-Cancer Therapy

Auteurs: Gábor Valcz, Edit I. Buzás, Anna Sebestyén, Tibor Krenács, Zoltán Szállási, Péter Igaz, Béla Molnár
Publié dans: Cancers, Numéro 12/8, 2020, Page(s) 2324, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12082324

The Medial Septum as a Potential Target for Treating Brain Disorders Associated With Oscillopathies

Auteurs: Yuichi Takeuchi, Anett J. Nagy, Lívia Barcsai, Qun Li, Masahiro Ohsawa, Kenji Mizuseki, Antal Berényi
Publié dans: Frontiers in Neural Circuits, Numéro 15, 2021, ISSN 1662-5110
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fncir.2021.701080

Opportunities and challenges in studying the extracellular vesicle corona.

Auteurs: Buzas EI.
Publié dans: Nature Cell Biology, 2022, ISSN 1465-7392
Éditeur: Nature Publishing Group
DOI: 10.1038/s41556-022-00983-z

Investigating the influence of taurochenodeoxycholic acid (TCDCA) on pancreatic cancer cell behavior: An RNA sequencing approach

Auteurs: Eleonóra Gál, Shahram Parvaneh, Vanda Miklós, Péter Hegyi, Lajos Kemény, Zoltán Veréb, Viktória Venglovecz
Publié dans: Journal of Biotechnology, Numéro 391, 2024, Page(s) 20-32, ISSN 0168-1656
Éditeur: Elsevier BV
DOI: 10.1016/j.jbiotec.2024.05.010

Genome-wide association study identifies susceptibility loci for acute myeloid leukemia

Auteurs: Wei-Yu Lin, Sarah E. Fordham, Eric Hungate, Nicola J. Sunter, Claire Elstob, Yaobo Xu, Catherine Park, Anne Quante, Konstantin Strauch, Christian Gieger, Andrew Skol, Thahira Rahman, Lara Sucheston-Campbell, Junke Wang, Theresa Hahn, Alyssa I. Clay-Gilmour, Gail L. Jones, Helen J. Marr, Graham H. Jackson, Tobias Menne, Mathew Collin, Adam Ivey, Robert K. Hills, Alan K. Burnett, Nigel H. Russell, J
Publié dans: Nature Communications, Numéro 12/1, 2021, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-021-26551-x

Two Decades of Evolution of Our Understanding of the Transient Receptor Potential Melastatin 2 (TRPM2) Cation Channel

Auteurs: Andras Szollosi
Publié dans: Life, Numéro 11/5, 2021, Page(s) 397, ISSN 2075-1729
Éditeur: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/life11050397

Biocompatible poly(ethylene succinate) polyester with molecular weight dependent drug release properties.

Auteurs: Abdelghafour MM, Orbán Á, Deák Á, Lamch Ł, Frank É, Nagy R, Ziegenheim S, Sipos P, Farkas E, Bari F, Janovák L.
Publié dans: Biomaterials, 2022, ISSN 0142-9612
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.ijpharm.2022.121653

Temporally Targeted Interactions With Pathologic Oscillations as Therapeutical Targets in Epilepsy and Beyond.

Auteurs: Földi T, Lőrincz ML and Berényi
Publié dans: Frontiers in Neural Circuits, 2021, ISSN 1662-5110
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fncir.2021.784085

Molecular imaging of bacterial outer membrane vesicles based on bacterial surface display.

Auteurs: Kövesdi D, Bősze S, Szabó I, Felföldi T, Oszwald E, Padmanabhan P, Gulyás BZ, Hamdani N, Máthé D, Varga Z, Szigeti K.
Publié dans: Scientific Reports, 2023, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-023-45628-9

Microenvironment shapes small-cell lung cancer neuroendocrine states and presents therapeutic opportunities

Auteurs: Parth Desai, Nobuyuki Takahashi, Rajesh Kumar, Samantha Nichols, Justin Malin, Allison Hunt, Christopher Schultz, Yingying Cao, Desiree Tillo, Darryl Nousome, Lakshya Chauhan, Linda Sciuto, Kimberly Jordan, Vinodh Rajapakse, Mayank Tandon, Delphine Lissa, Yang Zhang, Suresh Kumar, Lorinc Pongor, Abhay Singh, Brett Schroder, Ajit Kumar Sharma, Tiangen Chang, Rasa Vilimas, Danielle Pinkiert, Chante
Publié dans: Cell Reports Medicine, Numéro 5, 2024, Page(s) 101610, ISSN 2666-3791
Éditeur: Cell Press
DOI: 10.1016/j.xcrm.2024.101610

Multiple Layers of Complexity in O-Glycosylation Illustrated With the Urinary Glycoproteome.

Auteurs: Pap A, Kiraly IE, Medzihradszky KF, Darula Z.
Publié dans: Molecular and Cellular Proteomics, 2022, ISSN 1535-9476
Éditeur: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.mcpro.2022.100439

Intracellular Ca2+ Signalling in the Pathogenesis of Acute Pancreatitis: Recent Advances and Translational Perspectives

Auteurs: Petra Pallagi, Tamara Madácsy, Árpád Varga, József Maléth
Publié dans: International Journal of Molecular Sciences, Numéro 21/11, 2020, Page(s) 4005, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21114005

MiR-128-3p as blood based liquid biopsy biomarker in childhood acute lymphoblastic leukemia.

Auteurs: Rzepiel A, Horváth A, Kutszegi N, Gézsi A, Sági JC, Almási L, Egyed B, Lőrincz P, Visnovitz T, Kovács GT, Szalai C, Semsei ÁF, Erdélyi DJ.
Publié dans: Molecular and Cellular Probes, 2023, ISSN 0890-8508
Éditeur: Academic Press
DOI: 10.1016/j.mcp.2023.101893

Dry storage of mammalian spermatozoa and cells: state-of-the-art and possible future directions

Auteurs: P. Loi, D. A. Anzalone, L. Palazzese, A. Dinnyés, J. Saragusty, M. Czernik
Publié dans: Reproduction, Fertility and Development, Numéro 33/2, 2021, Page(s) 82, ISSN 1031-3613
Éditeur: Commonwealth Scientific and Industrial Research Organization Publishing
DOI: 10.1071/rd20264

TFLink: an integrated gateway to access transcription factor-target gene interactions for multiple species.

Auteurs: Liska O, Bohár B, Hidas A, Korcsmáros T, Papp B, Fazekas D, Ari E.
Publié dans: Database, Numéro 17580463, 2022, ISSN 1758-0463
Éditeur: Oxford University Press
DOI: 10.1093/database/baac083

The Skin–Brain Axis: From UV and Pigmentation to Behaviour Modulation

Auteurs: Anna A. Ascsillán, Lajos V. Kemény
Publié dans: International Journal of Molecular Sciences, Numéro 25, 2024, Page(s) 6199, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms25116199

Ejection Fraction-Related Differences of Baseline Characteristics and Outcomes in Troponin-Positive Patients without Obstructive Coronary Artery Disease

Auteurs: Mustafa Kacmaz, Clara Schlettert, Fabienne Kreimer, Mohammad Abumayyaleh, Ibrahim Akin, Andreas Mügge, Assem Aweimer, Nazha Hamdani, Ibrahim El-Battrawy
Publié dans: Journal of Clinical Medicine, Numéro 13, 2024, Page(s) 2826, ISSN 2077-0383
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm13102826

Predicting immune checkpoint therapy response in three independent metastatic melanoma cohorts

Auteurs: Leticia Szadai, Aron Bartha, Indira Pla Parada, Alexandra I.T. Lakatos, Dorottya M.P. Pál, Anna Sára Lengyel, Natália Pinto de Almeida, Ágnes Judit Jánosi, Fábio Nogueira, Beata Szeitz, Viktória Doma, Nicole Woldmar, Jéssica Guedes, Zsuzsanna Ujfaludi, Zoltán Gábor Pahi, Tibor Pankotai, Yonghyo Kim, Balázs Győrffy, Bo Baldetorp, Charlotte Welinder, A. Marcell Szasz, Lazaro Betancourt,
Publié dans: Frontiers in Oncology, Numéro 14, 2024, ISSN 2234-943X
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fonc.2024.1428182

Tumour Necrosis Factor Alpha-induced Protein 3 Negatively Regulates Cutibacterium acnes-induced Innate Immune Events in Epidermal Keratinocytes

Auteurs: Lilla Erdei, Beáta Szilvia Bolla, Renáta Bozó, Gábor Tax, Edit Urbán, Katalin Burián, Lajos Kemény, Kornélia Szabó
Publié dans: Acta Dermato-Venereologica, 2021, ISSN 0001-5555
Éditeur: Taylor & Francis
DOI: 10.2340/00015555-3707

Molecular characterization of immune checkpoint inhibitor-induced cardiotoxicity reveals IL-17A as a driver of cardiac dysfunction after anti-PD-1 treatment.

Auteurs: Gergely TG, Kucsera D, Tóth VE, Kovács T, Sayour NV, Drobni ZD, Ruppert M, Petrovich B, Ágg B, Onódi Z, Fekete N, Pállinger É, Buzás EI, Yousif LI, Meijers WC, Radovits T, Merkely B, Ferdinandy P, Varga ZV.
Publié dans: British Journal of Pharmacology, Numéro 00071188, 2022, ISSN 0007-1188
Éditeur: Wiley-Blackwell
DOI: 10.1111/bph.15984

Two-year event-free survival prediction in DLBCL patients based on in vivo radiomics and clinical parameters,

Auteurs: Zsombor Ritter, Laszlo Papp, Katalin Zámbó, Zoltan Tóth, Dániel Dezso, Dániel Sándor Veres, Domokos Máthé, Ferenc Budán, Éva Karádi, Anett Balikó, László Pajor, Árpád Szomor, Erzsébet Schmidt, Hussain Alizadeh
Publié dans: Hematologic Malignancies, 2022, ISSN 2234-943X
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.820136

Ca2+/calmodulin-dependent protein kinase II and protein kinase G oxidation contributes to impaired sarcomeric proteins in hypertrophy model.

Auteurs: Gömöri K, Herwig M, Budde H, Hassoun R, Mostafi N, Zhazykbayeva S, Sieme M, Modi S, Szabados T, Pipis J, Farkas-Morvay N, Leprán I, Ágoston G, Baczkó I, Kovács Á, Mügge A, Ferdinandy P, Görbe A, Bencsik P, Hamdani N.
Publié dans: ESC Heart Fail, 2022, ISSN 2055-5822
Éditeur: The Heart Failure Association of the European Society of Cardiology
DOI: 10.1002/ehf2.13973

Systematic transcriptomic and phenotypic characterization of human and murine cardiac myocyte cell lines and primary cardiomyocytes reveals serious limitations and low resemblances to adult cardiac phenotype. J Mol Cell Cardiol.

Auteurs: Onódi Z, Visnovitz T, Kiss B, Hambalkó S, Koncz A, Ágg B, Váradi B, Tóth VÉ, Nagy RN, Gergely TG, Gergő D, Makkos A, Pelyhe C, Varga N, Reé D, Apáti Á, Leszek P, Kovács T, Nagy N, Ferdinandy P, Buzás EI, Görbe A, Giricz Z, Varga ZV.
Publié dans: Journal of Molecular and Cellular Cardiology, 2021, ISSN 0022-2828
Éditeur: Academic Press
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Could basement membrane alterations, resembling micro‐wounds at the dermo‐epidermal junction in psoriatic non‐lesional skin, make the skin susceptible to lesion formation?

Auteurs: Renáta Bozó, Lili Borbála Flink, Nóra Belső, Barbara Gubán, Márta Széll, Lajos Kemény, Zsuzsanna Bata‐Csörgő
Publié dans: Experimental Dermatology, 2020, ISSN 0906-6705
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/exd.14267

Gyermekkori agydaganatok: diagnózis és terápia – komprehenzív genomikai profilozás [Childhood brain tumors: diagnosis and therapy - comprehensive genomic profiling].

Auteurs: Brückner E, Bedics G, Reiniger L, Rajnai H, Jakab Z, Bödör C, Scheich B, Garami M.
Publié dans: Magyar Onkológia, 2023, ISSN 0025-0244
Éditeur: Magyar Onkologusok Tarsasaga

Gene loss and compensatory evolution promotes the emergence of morphological novelties in budding yeast

Auteurs: Farkas Z, Kovács K, Sarkadi Z, Kalapis D, Fekete G, Birtyik F, Ayaydin F, Molnár C, Horváth P, Pál C, Papp B.
Publié dans: Nature Ecology and Evolution, 2022, ISSN 2397-334X
Éditeur: Nature Publishing Group
DOI: 10.1038/s41559-022-01730-1

Distinct miRNA Expression Signatures of Primary and Secondary Central Nervous System Lymphomas.

Auteurs: Sebestyén E, Nagy Á, Marosvári D, Rajnai H, Kajtár B, Deák B, Matolcsy A, Brandner S, Storhoff J, Chen N, Bagó AG, Bödör C, Reiniger L.
Publié dans: The journal of molecular diagnostics, 2021, ISSN 1525-1578
Éditeur: American Society for Investigative Pathology
DOI: 10.1016/j.jmoldx.2021.11.005

Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells

Auteurs: Roman C. Sarott, Matthias V. Westphal, Patrick Pfaff, Claudia Korn, David A. Sykes, Thais Gazzi, Benjamin Brennecke, Kenneth Atz, Marie Weise, Yelena Mostinski, Pattarin Hompluem, Eline Koers, Tamara Miljuš, Nicolas J. Roth, Hermon Asmelash, Man C. Vong, Jacopo Piovesan, Wolfgang Guba, Arne C. Rufer, Eric A. Kusznir, Sylwia Huber, Catarina Raposo, Elisabeth A. Zirwes, Anja Osterwald, Anto Pavlovi
Publié dans: Journal of the American Chemical Society, Numéro 142/40, 2020, Page(s) 16953-16964, ISSN 0002-7863
Éditeur: American Chemical Society
DOI: 10.1021/jacs.0c05587

FTO Intronic SNP Strongly Influences Human Neck Adipocyte Browning Determined by Tissue and PPARγ Specific Regulation: A Transcriptome Analysis

Auteurs: Beáta B. Tóth, Rini Arianti, Abhirup Shaw, Attila Vámos, Zoltán Veréb, Szilárd Póliska, Ferenc Győry, Zsolt Bacso, László Fésüs, Endre Kristóf
Publié dans: Cells, Numéro 9/4, 2020, Page(s) 987, ISSN 2073-4409
Éditeur: MDPI AG
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A series of xanthenes inhibiting Rad6 function and Rad6-Rad18 interaction in the PCNA ubiquitination cascade.

Auteurs: Fenteany G, Sharma G, Gaur P, Borics A, Wéber E, Kiss E, Haracska L.
Publié dans: iScience, 2022, ISSN 2589-0042
Éditeur: Elsevier Inc.
DOI: 10.1016/j.isci.2022.104053

Evidence of a Myenteric Plexus Barrier and its Macrophage-Dependent Degradation during Murine Colitis: Implications in Enteric Neuroinflammation

Auteurs: David Dora, Szilamer Ferenczi, Rhian Stavely, Viktoria E. Toth, Zoltan V. Varga, Tamas Kovacs, Ildiko Bodi, Ryo Hotta, Krisztina J. Kovacs, Allan M. Goldstein, Nandor Nagy
Publié dans: Cellular and Molecular Gastroenterology and Hepatology, 2021, ISSN 2352-345X
Éditeur: Elsevier Inc.
DOI: 10.1016/j.jcmgh.2021.07.003

Development of Polymer-Encapsulated, Amine-Functionalized Zinc Ferrite Nanoparticles as MRI Contrast Agents.

Auteurs: Ilosvai ÁM, Forgách L, Kovács N, Heydari F, Szigeti K, Máthé D, Kristály F, Daróczi L, Kaleta Z, Viskolcz B, Nagy M, Vanyorek L.
Publié dans: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242216203

Effect of hypercholesterolemia on circulating and cardiomyocyte-derived extracellular vesicles

Auteurs: Csenger Kovácsházi, Szabolcs Hambalkó, Nabil V. Sayour, Tamás G. Gergely, Gábor B. Brenner, Csilla Pelyhe, Dóra Kapui, Bennet Y. Weber, Alexander L. Hültenschmidt, Éva Pállinger, Edit I. Buzás, Ádám Zolcsák, Bálint Kiss, Tamás Bozó, Csilla Csányi, Nikolett Kósa, Miklós Kellermayer, Róbert Farkas, Gellért B. Karvaly, Kieran Wynne, David Matallanas, Péter Ferdinandy, Zoltán Gi
Publié dans: Scientific Reports, Numéro 14, 2024, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-024-62689-6

Effects of bowel cleansing on the composition of the gut microbiota in inflammatory bowel disease patients and healthy controls.

Auteurs: Bacsur P, Rutka M, Asbóth A, Resál T, Szántó K, Jójárt B, Bálint A, Ari E, Ajibola W, Kintses B, Fehér T, Pigniczki D, Bor R, Fábián A, Maléth J, Szepes Z, Farkas K, Molnár T.
Publié dans: Therapeutic Advances in Gastroenterology, 2023, ISSN 1756-283X
Éditeur: SAGE Publications
DOI: 10.1177/17562848231174298

Mechanisms of myocardial reverse remodelling and its clinical significance: A scientific statement of the ESC Working Group on Myocardial Function

Auteurs: Inês Falcão‐Pires, Ana Filipa Ferreira, Fábio Trindade, Luc Bertrand, Michele Ciccarelli, Valeria Visco, Dana Dawson, Nazha Hamdani, Linda W. Van Laake, Frank Lezoualc'h, Wolfgang A. Linke, Ida G Lunde, Peter P. Rainer, Mahmoud Abdellatif, Jolanda Van der Velden, Nicola Cosentino, Alessia Paldino, Giulio Pompilio, Serena Zacchigna, Stephane Heymans, Thomas Thum, Carlo Gabriele Tocchetti
Publié dans: European Journal of Heart Failure, Numéro 26, 2024, Page(s) 1454-1479, ISSN 1388-9842
Éditeur: Elsevier BV
DOI: 10.1002/ejhf.3264

Endoplasmic Reticulum‐Plasma Membrane Contact Sites as an Organizing Principle for Compartmentalized Calcium and cAMP Signaling

Auteurs: Tim Crul, József Maléth
Publié dans: International Journal of Molecular Sciences, Numéro 22/9, 2021, Page(s) 4703, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22094703

Dual amplification strategy turns TRPM2 channels into supersensitive central heat detectors.

Auteurs: Bartók Á, Csanády L.
Publié dans: Proceedings of the National Academy of Sciences of the United States of America, Numéro 00278424, 2022, ISSN 0027-8424
Éditeur: National Academy of Sciences
DOI: 10.1073/pnas.2212378119

Deciphering of Candida parapsilosis induced immune response in Drosophila melanogaster

Auteurs: Katalin Csonka, Zsolt Tasi, Viktor Vedelek, Csaba Vágvölgyi, Rita Sinka, Attila Gácser
Publié dans: Virulence, Numéro 12/1, 2021, Page(s) 2571-2582, ISSN 2150-5594
Éditeur: Landes Bioscience
DOI: 10.1080/21505594.2021.1980989

A novel BRET-Based GAP assay reveals phosphorylation-dependent regulation of the RAC-specific GTPase activating protein ARHGAP25.

Auteurs: Wisniewski É, Czárán D, Kovács F, Bahurek E, Németh A, Sasvári P, Szanda G, Pettkó-Szandtner A, Klement E, Ligeti E, Csépányi-Kömi R.
Publié dans: Faseb Journal, Numéro 08926638, 2022, ISSN 0892-6638
Éditeur: Federation of American Societies for Experimental Biology
DOI: 10.1096/fj.202200689r

Case Report: Development of Diffuse Large B Cell Lymphoma a Long Time After Hairy Cell Leukemia.

Auteurs: Nagy ZF, Ferenczi K, Istenes I, Eid H, Bödör C, Timár B, Demeter J.
Publié dans: Pathology and Oncology Research, 2022, ISSN 1532-2807
Éditeur: Frontiers Media S.A.
DOI: 10.3389/pore.2022.1610338

Inflammasome Activity in the Skeletal Muscle and Heart of Rodent Models for Duchenne Muscular Dystrophy. Int J Mol Sci. 2023 May 9;24(10):8497.

Auteurs: Onódi Z, Szabó PL, Kucsera D, Pokreisz P, Dostal C, Hilber K, Oudit GY, Podesser BK, Ferdinandy P, Varga ZV, Kiss A.
Publié dans: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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Commentary on ‘Sebocyte differentiation as a new target for acne therapy: an in vivo experience’

Auteurs: L. Kemény, K. Szabó
Publié dans: Journal of the European Academy of Dermatology and Venereology, Numéro 34/8, 2020, Page(s) 1637-1638, ISSN 0926-9959
Éditeur: Elsevier BV
DOI: 10.1111/jdv.16788

Lectin-Based Immunophenotyping and Whole Proteomic Profiling of CT-26 Colon Carcinoma Murine Model.

Auteurs: Faragó, A., Zvara, Á., Tiszlavicz, L., Hunyadi-Gulyás, É., Darula, Z., Hegedűs, Z., Szabó, E., Surguta, S. E., Tóvári, J., Puskás, L. G., & Szebeni, G. J.
Publié dans: International journal of molecular sciences, 2024, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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Rapid Evolution of Reduced Susceptibility against a Balanced Dual-Targeting Antibiotic through Stepping-Stone Mutations

Auteurs: Petra Szili, Gábor Draskovits, Tamás Révész, Ferenc Bogár, Dávid Balogh, Tamás Martinek, Lejla Daruka, Réka Spohn, Bálint Márk Vásárhelyi, Márton Czikkely, Bálint Kintses, Gábor Grézal, Györgyi Ferenc, Csaba Pál, Ákos Nyerges
Publié dans: Antimicrobial Agents and Chemotherapy, Numéro 63/9, 2019, ISSN 0066-4804
Éditeur: American Society for Microbiology
DOI: 10.1128/aac.00207-19

Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes.

Auteurs: Casado P, Rio-Machin A, Miettinen JJ, Bewicke-Copley F, Rouault-Pierre K, Krizsan S, Parsons A, Rajeeve V, Miraki-Moud F, Taussig DC, Bödör C, Gribben J, Heckman C, Fitzgibbon J, Cutillas PR.
Publié dans: Signal Transduction and Targeted Therapy, 2023, ISSN 2059-3635
Éditeur: Springer Nature
DOI: 10.1038/s41392-022-01288-1

Local laboratory-run donor-derived cell-free DNA assay for rejection surveillance in heart transplantation-first six months of clinical experience.

Auteurs: Teszak T, Bödör C, Hegyi L, Levay L, Nagy B, Fintha A, Merkely B, Sax B.
Publié dans: Clinical Transplantation, 2023, ISSN 1399-0012
Éditeur: Wiley-Blavkwell Publishing Ltd.
DOI: 10.1111/ctr.15078

Co-Detection of VEGF-A and Its Regulator, microRNA-181a, May Indicate Central Nervous System Involvement in Pediatric Leukemia

Auteurs: Egyed B, Horváth A, Semsei ÁF, Szalai C, Müller J, Erdélyi DJ, Kovács GT
Publié dans: Pathology and Oncology Research, 2022, ISSN 1219-4956
Éditeur: Springer Verlag
DOI: 10.3389/pore.2022.1610096

Amino Acid Polymorphisms in the VHIID Conserved Motif of Nodulation Signaling Pathways 2 Distinctly Modulate Symbiotic Signaling and Nodule Morphogenesis in Medicago truncatula.

Auteurs: Kovacs S, Fodor L, Domonkos A, Ayaydin F, Laczi K, Rákhely G and Kalo P
Publié dans: Frontiers in plant science, 2021, ISSN 1664-462X
Éditeur: Frontiers Media S. A.
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Age-Related Inflammatory Balance Shift, Nasal Barrier Function, and Cerebro-Morphological Status in Healthy and Diseased Rodents

Auteurs: Zsófia Varga-Medveczky, Noémi Kovács, Melinda E. Tóth, Miklós Sántha, Ildikó Horváth, Luca Anna Bors, Katalin Fónagy, Timea Imre, Pál Szabó, Domokos Máthé, Franciska Erdő
Publié dans: Frontiers in Neuroscience, Numéro 15, 2021, ISSN 1662-453X
Éditeur: Frontiers Media S.A.
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Emerging human pulmonary dirofilariasis in Hungary: a single center experience

Auteurs: Levente Kuthi, Tamás Zombori, László Tiszlavicz, Fanni Hegedűs, Szintia Almási, Bence Baráth, Mohammed Almakrami, Mohammad Jamal EJ, Nikolett Barta, Zsuzsanna Ujfaludi, Tibor Pankotai, Adrienn Hajdu, József Furák, Anita Sejben
Publié dans: Diagnostic Pathology, Numéro 19, 2024, ISSN 1746-1596
Éditeur: BioMed Central
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Bile acid- and ethanol-mediated activation of Orai1 damages pancreatic ductal secretion in acute pancreatitis.

Auteurs: Pallagi P, Görög M, Papp N, Madácsy T, Varga Á, Crul T, Szabó V, Molnár M, Dudás K, Grassalkovich A, Szederkényi E, Lázár G, Venglovecz V, Hegyi P, Maléth J.
Publié dans: The journal of physiology A publication of the Physiological Society., 2022, ISSN 1469-7793
Éditeur: The journal of physiology
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Hepatocyte vitamin D receptor functions as a nutrient sensor that regulates energy storage and tissue growth in zebrafish

Auteurs: Scott H. Freeburg, Arkadi Shwartz, Lajos V. Kemény, Colton J. Smith, Olivia Weeks, Bess M. Miller, Nadia PenkoffLidbeck, David E. Fisher, Kimberley J. Evason, Wolfram Goessling
Publié dans: Cell Reports, Numéro 43, 2024, Page(s) 114393, ISSN 2211-1247
Éditeur: Cell Press
DOI: 10.1016/j.celrep.2024.114393

Saxagliptin Cardiotoxicity in Chronic Heart Failure: The Role of DPP4 in the Regulation of Neuropeptide Tone.

Auteurs: Vörös I, Onódi Z, Tóth VÉ, Gergely TG, Sághy É, Görbe A, Kemény Á, Leszek P, Helyes Z, Ferdinandy P, Varga ZV.
Publié dans: Biomedicines, 2022, ISSN 2227-9059
Éditeur: MDPI AG
DOI: 10.3390/biomedicines10071573

BC-Monitor: Towards a Routinely Accessible Circulating Tumor DNA-Based Tool for Real-Time Monitoring Breast Cancer Progression and Treatment Effectiveness

Auteurs: Katalin Priskin, Sára Pólya, Lajos Pintér, Gábor Jaksa, Bernadett Csányi, Márton Zsolt Enyedi, Eszter Sági-Zsigmond, Farkas Sükösd, Orsolya Oláh-Németh, Gyöngyi Kelemen, Alíz Nikolényi, Gabriella Uhercsák, Dóra Sántha, Ágnes Dobi, Éva Szilágyi, Erzsébet Valicsek, László Tordai, Rozália Tóth, Zsuzsanna Kahán, Lajos Haracska
Publié dans: Cancers, Numéro 13/14, 2021, Page(s) 3489, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13143489

Impacts of gene variants on drug effects-the foundation of genotype-guided pharmacologic therapy for long QT syndrome and short QT syndrome

Auteurs: Zhihan Zhao, Xiaobiao Zang, Kerun Niu, Weifeng Song, Xianqing Wang, Andreas Mügge, Assem Aweimer, Nazha Hamdani, Xiaobo Zhou, Yonghui Zhao, Ibrahim Akin, Ibrahim El-Battrawy
Publié dans: eBioMedicine, Numéro 103, 2024, Page(s) 105108, ISSN 2352-3964
Éditeur: Elsevier BV
DOI: 10.1016/j.ebiom.2024.105108

GATA2 deficiency and MDS/AML: Experimental strategies for disease modelling and future therapeutic prospects.

Auteurs: Kotmayer L, Romero-Moya D, Marin-Bejar O, Kozyra E, Català A, Bigas A, Wlodarski MW, Bödör C, Giorgetti A.
Publié dans: British Journal of Haematology, 2022, ISSN 0007-1048
Éditeur: Blackwell Publishing Inc.
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Spreading depolarization causes reperfusion failure after cerebral ischemia.

Auteurs: Törteli A, Tóth R, Berger S, Samardzic S, Bari F, Menyhárt Á, Farkas E.
Publié dans: Journal of Cerebral Blood Flow and Metabolism, 2023, ISSN 0271-678X
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1177/0271678x231153745

Characterization of antibiotic resistomes by reprogrammed bacteriophage-enabled functional metagenomics in clinical strains.

Auteurs: Apjok G, Számel M, Christodoulou C, Seregi V, Vásárhelyi BM, Stirling T, Eszenyi B, Sári T, Vidovics F, Nagrand E, Kovács D, Szili P, Lantos II, Méhi O, Jangir PK, Herczeg R, Gálik B, Urbán P, Gyenesei A, Draskovits G, Nyerges Á, Fekete G, Bodai L, Zsindely N, Dénes B, Yosef I, Qimron U, Papp B, Pál C, Kintses B.
Publié dans: Nature Microbiology, 2023, ISSN 2058-5276
Éditeur: Nature Publishing Group
DOI: 10.1038/s41564-023-01320-2

Symphony of surprises: Unveiling organ interactions in Takotsubo Syndrome

Auteurs: Daniel Strohleit, Assem Aweimer, Ibrahim Akin, Nazha Hamdani, Ibrahim El-Battrawy
Publié dans: International Journal of Cardiology, Numéro 408, 2024, Page(s) 132148, ISSN 0167-5273
Éditeur: Elsevier BV
DOI: 10.1016/j.ijcard.2024.132148

Bile accelerates carcinogenic processes in pancreatic ductal adenocarcinoma cells through the overexpression of MUC4

Auteurs: Eleonóra Gál, Zoltán Veréb, Lajos Kemény, Dávid Rakk, András Szekeres, Eszter Becskeházi, László Tiszlavicz, Tamás Takács, László Czakó, Péter Hegyi, Viktória Venglovecz
Publié dans: Scientific Reports, Numéro 10/1, 2020, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-020-79181-6

The loss of DNA polymerase epsilon accessory subunits POLE3–POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

Auteurs: Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, Eva Pinto Jurado, Siham Zentout, Alexandra Mihuţ, Anna Georgina Kopasz, Mihály Mérey, Rebecca Smith, Abhishek Bharadwaj Sharma, Nicholas D Lakin, Andrew James Bowman, Lajos Haracska, Sébastien Huet, Gyula Timinszky
Publié dans: Nucleic Acids Research, Numéro 52, 2024, Page(s) 6994-7011, ISSN 0305-1048
Éditeur: Oxford University Press
DOI: 10.1093/nar/gkae439

Evaluation of the impact of iPSC differentiation protocols on transcriptomic signatures.

Auteurs: Chandrasekaran, V., Wellens, S., Bourguignon, A., Djidrovski, I., Fransen, L., Ghosh, S., Mazidi, Z., Murphy, C., Nunes, C., Singh, P., Zana, M., Armstrong, L., Dinnyés, A., Grillari, J., Grillari-Voglauer, R., Leonard, M. O., Verfaillie, C., Wilmes, A., Zurich, M. G., Exner, T., … Culot, M.
Publié dans: Toxicology in vitro, 2024, ISSN 0887-2333
Éditeur: Elsevier BV
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Werner helicase interacting protein 1 contributes to G-quadruplex processing in human cells

Auteurs: Lili Hegedus, Agnes Toth, Gabor M. Harami, Janos Palinkas, Nargis Karatayeva, Eniko Sajben-Nagy, Szabolcs Bene, Sara Afzali Jaktajdinani, Mihaly Kovacs, Szilvia Juhasz, Peter Burkovics
Publié dans: Scientific Reports, Numéro 14, 2024, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-024-66425-y

Chloroplast phosphate transporter CrPHT4-7 regulates phosphate homeostasis and photosynthesis in Chlamydomonas.

Auteurs: Tóth D, Kuntam S, Ferenczi Á, Vidal-Meireles A, Kovács L, Wang L, Sarkadi Z, Migh E, Szentmihályi K, Tengölics R, Neupert J, Bock R, Jonikas MC, Molnar A, Tóth SZ.
Publié dans: Plant Phsyiology, 2023, ISSN 0032-0889
Éditeur: American Society of Plant Biologists
DOI: 10.1093/plphys/kiad607

Insights into the Structure of Comirnaty Covid-19 Vaccine: A Theory on Soft, Partially Bilayer-Covered Nanoparticles with Hydrogen Bond-Stabilized mRNA-Lipid Complexes.

Auteurs: Szebeni J, Kiss B, Bozó T, Turjeman K, Levi-Kalisman Y, Barenholz Y, Kellermayer M.
Publié dans: ACS Nano, 2023, ISSN 1936-086X
Éditeur: American Chemical Society
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Case report: Complete and durable response to larotrectinib (TRK inhibitor) in an infant diagnosed with angiosarcoma harbouring a KHDRBS1-NTRK3 fusion gene.

Auteurs: Cervi C, Sápi Z, Bedics G, Zajta E, Hegyi L, Pápay J, Dezső K, Varga E, Mudra K, Bödör C, Csóka M.
Publié dans: Frontiers in Oncology, 2023, ISSN 2234-943X
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fonc.2023.999810

Impact of Experimental Conditions on Extracellular Vesicles' Proteome: A Comparative Study.

Auteurs: Böröczky T, Dobra G, Bukva M, Gyukity-Sebestyén E, Hunyadi-Gulyás É, Darula Z, Horváth P, Buzás K, Harmati M.
Publié dans: Life, 2023, ISSN 2075-1729
Éditeur: MDPI
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CRISPR/Cas9 Mutagenesis through Introducing a Nanoparticle Complex Made of a Cationic Polymer and Nucleic Acids into Maize Protoplasts.

Auteurs: Nagy B, Öktem A, Ferenc G, Ungor D, Kalac A, Kelemen-Valkony I, Fodor E, Nagy I, Dudits D, Ayaydin F.
Publié dans: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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Blood-brain barrier dysfunction in L-ornithine induced acute pancreatitis in rats and the direct effect of L-ornithine on cultured brain endothelial cells.

Auteurs: Walter FR, Harazin A, Tóth AE, Veszelka S, Santa-Maria AR, Barna L, Kincses A, Biczó G, Balla Z, Kui B, Maléth J, Cervenak L, Tubak V, Kittel Á, Rakonczay Z Jr, Deli MA
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PCSK9 in Myocardial Infarction and Cardioprotection: Importance of Lipid Metabolism and Inflammation

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The Medicago truncatula nodule-specific cysteine-rich peptides, NCR343 and NCR-new35 are required for the maintenance of rhizobia in nitrogen-fixing nodules.

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The Small Heat Shock Protein, HSPB1, Interacts with and Modulates the Physical Structure of Membranes

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The RUNX1 Database (RUNX1db): establishment of an expert curated RUNX1 registry and genomics database as a public resource for familial platelet disorder with myeloid malignancy

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A Randomized Controlled Trial with a Medical Device Containing Sodium Hyaluronate and Nicotinic Acid to Increase the Efficacy of Ultraviolet Phototherapy in Psoriasis

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Psychological Effects of the COVID-19 Pandemic on Hungarian Adults

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A High-Throughput Clinical Laboratory Methodology for the Therapeutic Monitoring of Ibrutinib and Dihydrodiol Ibrutinib.

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Male and Female Animals Respond Differently to High-Fat Diet and Regular Exercise Training in a Mouse Model of Hyperlipidemia

Auteurs: Melinda E. Tóth, Brigitta Dukay, Mária Péter, Gábor Balogh, Gergő Szűcs, Ágnes Zvara, Gábor J. Szebeni, Petra Hajdu, Márta Sárközy, László G. Puskás, Zsolt Török, Tamás Csont, László Vígh, Miklós Sántha
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The Effect of Molecular Weight on the Solubility Properties of Biocompatible Poly(ethylene succinate) Polyester

Auteurs: Mohamed M. Abdelghafour, Ágoston Orbán, Ágota Deák, Łukasz Lamch, Éva Frank, Roland Nagy, Adél Ádám, Pál Sipos, Eszter Farkas, Ferenc Bari, László Janovák
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Functional Anatomical Changes in Ulcerative Colitis Patients Determine Their Gut Microbiota Composition and Consequently the Possible Treatment Outcome

Auteurs: Anita Bálint, Klaudia Farkas, Orsolya Méhi, Bálint Kintses, Bálint Márk Vásárhelyi, Eszter Ari, Csaba Pál, Tamara Madácsy, József Maléth, Kata Judit Szántó, István Nagy, Mariann Rutka, Péter Bacsur, Diána Szűcs, Zoltán Szepes, Ferenc Nagy, Anna Fábián, Renáta Bor, Ágnes Milassin, Tamás Molnár
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Cutibacterium acnes regulates the epidermal barrier properties of HPV-KER human immortalized keratinocyte cultures

Auteurs: Beáta Szilvia Bolla, Lilla Erdei, Edit Urbán, Katalin Burián, Lajos Kemény, Kornélia Szabó
Publié dans: Scientific Reports, Numéro 10/1, 2020, ISSN 2045-2322
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New targets and indications for probenecid.

Auteurs: Onódi Z, Koch S, Rubinstein J, Ferdinandy P, Varga ZV.
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Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe.

Auteurs: Gazzi T, Brennecke B, Atz K, Korn C, Sykes D, Forn-Cuni G, Pfaff P, Sarott RC, Westphal MV, Mostinski Y, Mach L, Wasinska-Kalwa M, Weise M, Hoare BL, Miljuš T, Mexi M, Roth N, Koers EJ, Guba W, Alker A, Rufer AC, Kusznir EA, Huber S, Raposo C, Zirwes EA, Osterwald A, Pavlovic A, Moes S, Beck J, Nettekoven M, Benito-Cuesta I, Grande T, Drawnel F, Widmer G, Holzer D, van der Wel T, Mandhair H, Hone
Publié dans: Chemical Science, 2022, ISSN 2041-6520
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ING1 inhibits Twist1 expression to block EMT and is antagonized by the HDAC inhibitor vorinostat.

Auteurs: Yang Y, Ma B, Djamshidi M, Zhang Q, Sarkar A, Chanda A, Tran U, Soh J, Sandall C, Chen HM, MacDonald JA, Bonni S, Sensen CW, Zheng J, Riabowol K.
Publié dans: European Journal of Cell Biology, 2023, ISSN 1618-1298
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Protein Kinase D Plays a Crucial Role in Maintaining Cardiac Homeostasis by Regulating Post-Translational Modifications of Myofilament Proteins.

Auteurs: Herwig, M., Begovic, M., Budde, H., Delalat, S., Zhazykbayeva, S., Sieme, M., Schneider, L., Jaquet, K., Mügge, A., Akin, I., El-Battrawy, I., Fielitz, J., & Hamdani, N.
Publié dans: International journal of molecular sciences, 2024, ISSN 1422-0067
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Grafted human induced pluripotent stem cells improve the outcome of spinal cord injury: modulation of the lesion microenvironment

Auteurs: Tamás Bellák, Zoltán Fekécs, Dénes Török, Zsuzsanna Táncos, Csilla Nemes, Zsófia Tézsla, László Gál, Suchitra Polgári, Julianna Kobolák, András Dinnyés, Antal Nógrádi, Krisztián Pajer
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Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41.

Auteurs: Homan CC, Drazer MW, Yu K, Lawrence DM, Feng J, Arriola-Martinez L, Pozsgai MJ, McNeely KE, Ha T, Venugopal P, Arts P, King-Smith SL, Cheah J, Armstrong M, Wang P, Bödör C, Cantor AB, Cazzola M, Degelman E, DiNardo CD, Duployez N, Favier R, Fröhling S, Rio-Machin A, Klco JM, Krämer A, Kurokawa M, Lee J, Malcovati L, Morgan NV, Natsoulis G, Owen C, Patel KP, Preudhomme C, Raslova H, Rienhoff H,
Publié dans: Blood Advances, 2023, ISSN 2473-9529
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SerpinB10, a Serine Protease Inhibitor, Is Implicated in UV-Induced Cellular Response

Auteurs: Hajnalka Majoros, Barbara N. Borsos, Zsuzsanna Ujfaludi, Zoltán G. Páhi, Mónika Mórocz, Lajos Haracska, Imre Miklós Boros, Tibor Pankotai
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Regenerative Neurology and Regenerative Cardiology: Shared Hurdles and Achievements

Auteurs: Mitrečić D, Hribljan V, Jagečić D, Isaković J, Lamberto F, Horánszky A, Zana M, Foldes G, Zavan B, Pivoriūnas A, Martinez S, Mazzini L, Radenovic L, Milasin J, Chachques JC, Buzanska L, Song MS, Dinnyés A.
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Chronic treatment with rofecoxib but not ischemic preconditioning of the myocardium ameliorates early intestinal damage following cardiac ischemia/reperfusion injury in rats

Auteurs: Szilvia B. László, Bernadette Lázár, Gábor B. Brenner, András Makkos, Mihály Balogh, Mahmoud Al-Khrasani, Barbara Hutka, Amir Mohammadzadeh, Ágnes Kemény, Terézia László, Bálint Scheich, Tamara Szabados, Éva Kenyeres, Zoltán Giricz, Péter Bencsik, Zoltán V. Varga, Julianna Novák, Zsuzsanna Helyes, Péter Ferdinandy, Klára Gyires, Zoltán S. Zádori
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Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.

Auteurs: Bullinger L, Rosenquist R, Vassilakopoulos TP, Ott G, Ogawa S, Damm F.
Publié dans: Leukemia, 2023, ISSN 0887-6924
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MMP-9 as Prognostic Marker for Brain Tumours: A Comparative Study on Serum-Derived Small Extracellular Vesicles.

Auteurs: Dobra G, Gyukity-Sebestyén E, Bukva M, Harmati M, Nagy V, Szabó Z, Pankotai T, Klekner Á, Buzás K.
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Primary microglia cell cultures in translational research: Strengths and limitations.

Auteurs: Pesti, I., Légrádi, Á., & Farkas, E.
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BRAF RNA is prognostic and widely expressed in lung adenocarcinoma.

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Publié dans: Translational Lung Cancer Research, 2023, ISSN 2218-6751
Éditeur: Society for Translational Medicine
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Heart failure pharmacotherapy and cancer: pathways and pre-clinical/clinical evidence.

Auteurs: Sayour, N. V., Paál, Á. M., Ameri, P., Meijers, W. C., Minotti, G., Andreadou, I., Lombardo, A., Camilli, M., Drexel, H., Grove, E. L., Dan, G. A., Ivanescu, A., Semb, A. G., Savarese, G., Dobrev, D., Crea, F., Kaski, J. C., de Boer, R. A., Ferdinandy, P., & Varga, Z. V.
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Reviewing critical TRPM2 variants through a structure-function lens

Auteurs: Tóth, Á. V., & Bartók, Á.
Publié dans: Journal of biotechnology, 2024, ISSN 0168-1656
Éditeur: Elsevier BV
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IL-36α and Lipopolysaccharide Cooperatively Induce Autophagy by Triggering Pro-Autophagic Biased Signaling

Auteurs: Zaid I. I. Al-Luhaibi, Áron Dernovics, György Seprényi, Ferhan Ayaydin, Zsolt Boldogkői, Zoltán Veréb, Klára Megyeri
Publié dans: Biomedicines, Numéro 9/11, 2021, Page(s) 1541, ISSN 2227-9059
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Acquired somatic variants in inherited myeloid malignancies.

Auteurs: Armes H, Rio-Machin A, Krizsán S, Bödör C, Kaya F, Bewicke-Copley F, Alnajar J, Walne A, Péterffy B, Tummala H, Rouault-Pierre K, Dokal I, Vulliamy T, Fitzgibbon J.
Publié dans: Leukemia, 2022, ISSN 0887-6924
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BTK and PLCG2 remain unmutated in one third of patients with CLL relapsing on ibrutinib.

Auteurs: Bonfiglio S, Sutton LA, Ljungström V, Capasso A, Pandzic T, Weström S, Foroughi-Asl H, Skaftason A, Gellerbring A, Lyander A, Gandini F, Gaidano G, Trentin L, Bonello L, Reda G, Bödör C, Stavroyianni N, Tam CS, Marasca R, Forconi F, Panayiotidis P, Ringshausen I, Jaksic O, Frustaci AM, Iyengar S, Coscia M, Mulligan SP, Ysebaert L, Strugov V, Pavlovsky C, Walewska R, Österborg A, Cortese D, Ra
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Underground metabolism as a rich reservoir for pathway engineering.

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The Arabidopsis Rho of Plants GTPase ROP1 Is a Potential Calcium-Dependent Protein Kinase (CDPK) Substrate

Auteurs: Dalma Ménesi; Éva Klement; Györgyi Ferenc; Attila Fehér
Publié dans: MDPI, Numéro 2, 2021, ISSN 1424-3210
Éditeur: MDPI Plants
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Advances in phototherapy for psoriasis and atopic dermatitis

Auteurs: Lajos Kemény, Emese Varga, Zoltan Novak
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Maternal One-Carbon Metabolism during the Periconceptional Period and Human Foetal Brain Growth: A Systematic Review

Auteurs: Eleonora Rubini, Inge M. M. Baijens, Alex Horánszky, Sam Schoenmakers, Kevin D. Sinclair, Melinda Zana, András Dinnyés, Régine P. M. Steegers-Theunissen, Melek Rousian
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The golden ages of inflammatory skin diseases: skyrocketing developments in the therapy of psoriasis and atopic dermatitis

Auteurs: L. Kemény
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Hydrogen peroxide production by epidermal dual oxidase 1 regulates nociceptive sensory signals.

Auteurs: Pató A, Bölcskei K, Donkó Á, Kaszás D, Boros M, Bodrogi L, Várady G, Pape VFS, Roux BT, Enyedi B, Helyes Z, Watt FM, Sirokmány G, Geiszt M.
Publié dans: Redox Biology, 2023, ISSN 2213-2317
Éditeur: Elsevier BV
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Extracellular vesicle release and uptake by the liver under normo- and hyperlipidemia

Auteurs: Krisztina Németh, Zoltán Varga, Dorina Lenzinger, Tamás Visnovitz, Anna Koncz, Nikolett Hegedűs, Ágnes Kittel, Domokos Máthé, Krisztián Szigeti, Péter Lőrincz, Clodagh O’Neill, Róisín Dwyer, Zhonglin Liu, Edit I. Buzás, Viola Tamási
Publié dans: Cellular and Molecular Life Sciences, 2021, ISSN 1420-682X
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Screening and monitoring of the BTK C481S mutation in a real‐world cohort of patients with relapsed/refractory chronic lymphocytic leukaemia during ibrutinib therapy

Auteurs: Csaba Bödör, Lili Kotmayer, Tamás László, Ferenc Takács, Gábor Barna, Richárd Kiss, Endre Sebestyén, Tibor Nagy, Lajos László Hegyi, Gábor Mikala, Sándor Fekete, Péter Farkas, Alexandra Balogh, Tamás Masszi, Judit Demeter, Júlia Weisinger, Hussain Alizadeh, Béla Kajtár, Zoltán Kohl, Róbert Szász, Lajos Gergely, Timea Gurbity Pálfi, Adrienn Sulák, Balázs Kollár, Miklós Egy
Publié dans: British Journal of Haematology, 2021, ISSN 0007-1048
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Morphologic and molecular analysis of Richter syndrome in chronic lymphocytic leukaemia patients treated with ibrutinib or venetoclax

Auteurs: Ambrus Gángó, Richárd Kiss, Péter Farkas, Eid Hanna, Judit Demeter, Beáta Deák, Dóra Lévai, Lili Kotmayer, Donát Alpár, András Matolcsy, Csaba Bödör, Zoltán Mátrai, Botond Timár
Publié dans: Pathology, 2021, ISSN 0031-3025
Éditeur: Taylor & Francis
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Novel RICTOR amplification harbouring entities: FISH validation of RICTOR amplification in tumour tissue after next-generation sequencing.

Auteurs: Sztankovics D, Krencz I, Moldvai D, Dankó T, Nagy Á, Nagy N, Bedics G, Rókusz A, Papp G, Tőkés AM, Pápay J, Sápi Z, Dezső K, Bödör C, Sebestyén A.
Publié dans: Scientific Reports, 2023, ISSN 2045-2322
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The EHA Research Roadmap: Malignant Lymphoid Diseases.

Auteurs: Dreyling M, André M, Gökbuget N, Tilly H, Jerkeman M, Gribben J, Ferreri A, Morel P, Stilgenbauer S, Fox C, Maria Ribera J, Zweegman S, Aurer I, Bödör C, Burkhardt B, Buske C, Dollores Caballero M, Campo E, Chapuy B, Davies A, de Leval L, Doorduijn J, Federico M, Gaulard P, Gay F, Ghia P, Grønbæk K, Goldschmidt H, Kersten MJ, Kiesewetter B, Landman-Parker J, Le Gouill S, Lenz G, Leppä S, Lo
Publié dans: HemaSphere, 2022, ISSN 2572-9241
Éditeur: Wolters Kluwer Health
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Plasminogen activator inhibitor 1 is a novel faecal biomarker for monitoring disease activity and therapeutic response in inflammatory bowel diseases.

Auteurs: Jójárt B, Resál T, Kata D, Molnár T, Bacsur P, Szabó V, Varga Á, Szántó KJ, Pallagi P, Földesi I, Molnár T, Maléth J, Farkas K.
Publié dans: Journal of Corhn's Colitis, 2023, ISSN 1873-9946
Éditeur: Elsevier Science
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Alcohol in Psoriasis—From Bench to Bedside

Auteurs: Zita Szentkereszty-Kovács, Krisztián Gáspár, Andrea Szegedi, Lajos Kemény, Dóra Kovács, Dániel Törőcsik
Publié dans: International Journal of Molecular Sciences, Numéro 22/9, 2021, Page(s) 4987, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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Chronic Cerebral Hypoperfusion-Induced Disturbed Proteostasis of Mitochondria and MAM Is Reflected in the CSF of Rats by Proteomic Analysis.

Auteurs: Tukacs V, Mittli D, Hunyadi-Gulyás É, Hlatky D, Medzihradszky KF, Darula Z, Nyitrai G, Czurkó A, Juhász G, Kardos J, Kékesi KA.
Publié dans: Molecular Neurobiology, 2023, ISSN 0893-7648
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The Combination of Single-Cell and Next-Generation Sequencing Can Reveal Mosaicism for BRCA2 Mutations and the Fine Molecular Details of Tumorigenesis

Auteurs: Alexandra Gráf, Márton Zsolt Enyedi, Lajos Pintér, Éva Kriston-Pál, Gábor Jaksa, Árpád Bálind, Éva Ezer, Péter Horváth, Farkas Sükösd, Ernő Kiss, Lajos Haracska
Publié dans: Cancers, Numéro 13/10, 2021, Page(s) 2354, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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Environmental Alterations during Embryonic Development: Studying the Impact of Stressors on Pluripotent Stem Cell-Derived Cardiomyocytes

Auteurs: Federica Lamberto, Irene Peral-Sanchez, Suchitra Muenthaisong, Melinda Zana, Sandrine Willaime-Morawek, András Dinnyés
Publié dans: Genes, Numéro 12/10, 2021, Page(s) 1564, ISSN 2073-4425
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Exploring RAD18-dependent replication of damaged DNA and discontinuities: A collection of advanced tools.

Auteurs: Mórocz M, Qorri E, Pekker E, Tick G, Haracska L.
Publié dans: Journal of Biotechnology, 2024, ISSN 0168-1656
Éditeur: Elsevier BV
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Genetic Investigation of Inverse Psoriasis

Auteurs: Anikó Göblös, Emese Varga, Katalin Farkas, Kristóf Árvai, Lajos Kemény
Publié dans: Life, Numéro 11/7, 2021, Page(s) 654, ISSN 2075-1729
Éditeur: MDPI Multidisciplinary Digital Publishing Institute
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Mitochondrial dysfunction and immune suppression in BRAF V600E‐mutated metastatic melanoma

Auteurs: Natália Pinto de Almeida, Ágnes Judit Jánosi, Runyu Hong, Ahmad Rajeh, Fábio Nogueira, Leticia Szadai, Beata Szeitz, Indira Pla Parada, Viktória Doma, Nicole Woldmar, Jéssica Guedes, Zsuzsanna Újfaludi, Aron Bartha, Yonghyo Kim, Charlotte Welinder, Bo Baldetorp, Lajos Vince Kemény, Zoltan Pahi, Guihong Wan, Nga Nguyen, Tibor Pankotai, Balázs Győrffy, Krzysztof Pawłowski, Peter Horvatovi
Publié dans: Clinical and Translational Medicine, Numéro 14, 2024, ISSN 2001-1326
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Deep Proteomic Analysis on Biobanked Paraffine-Archived Melanoma with Prognostic/Predictive Biomarker Read-Out.

Auteurs: Szadai L, Velasquez E, Szeitz B, Almeida NPd, Domont G, Betancourt LH, Gil J, Marko-Varga M, Oskolas H, Jánosi ÁJ, Boyano-Adánez MdC, Kemény L, Baldetorp B, Malm J, Horvatovich P, Szász AM, Németh IB, Marko-Varga G.
Publié dans: Cancers, 2021, Page(s) 13(23):6105, ISSN 2072-6694
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HCN channels at the cell soma ensure the rapid electrical reactivity of fast-spiking interneurons in human neocortex.

Auteurs: Szegedi V, Bakos E, Furdan S, Kovács BH, Varga D, Erdélyi M, Barzó P, Szücs A, Tamás G, Lamsa K.
Publié dans: PlOS Biology, 2023, ISSN 1544-9173
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Parathyroid cancer with MTOR gene mutation: Case report and review of the literature.

Auteurs: Stark J, Tőke J, Huszty G, Nagy P, Bedics G, Bödör C, Tímár J, Tóth M.
Publié dans: Annales d'Endocrinologie, 2023, ISSN 0003-4266
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Tamás SX, Roux BT, Vámosi B, Dehne FG, Török A, Fazekas L, Enyedi B.

Auteurs: A genetically encoded sensor for visualizing leukotriene B4 gradients in vivo.
Publié dans: Nature Communications, 2023, ISSN 2041-1723
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Fibroblast-Derived Extracellular Vesicles Induce Colorectal Cancer Progression by Transmitting Amphiregulin

Auteurs: Ádám Oszvald, Zsuzsanna Szvicsek, Márton Pápai, Andrea Kelemen, Zoltán Varga, Tamás Tölgyes, Kristóf Dede, Attila Bursics, Edit I. Buzás, Zoltán Wiener
Publié dans: Frontiers in Cell and Developmental Biology, Numéro 8, 2020, ISSN 2296-634X
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Understanding Differences in Sex-Based Outcomes with Dual Antiplatelet Therapy After Percutaneous Coronary Intervention

Auteurs: Ibrahim Akin, Nazha Hamdani, Ibrahim El-Battrawy
Publié dans: Drugs, Numéro 84, 2024, Page(s) 703-705, ISSN 0012-6667
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PACAP-38 and PAC1 Receptor Alterations in Plasma and Cardiac Tissue Samples of Heart Failure Patients.

Auteurs: Szabó D, Sárszegi Z, Polgár B, Sághy É, Reglődi D, Tóth T, Onódi Z, Leszek P, Varga ZV, Helyes Z, Kemény Á, Ferdinandy P, Tamás A.
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CD3+/CD56+ NKT-like Cells Show Imbalanced Control Immediately after Exercise in Delayed-Onset Muscle Soreness.

Auteurs: Sonkodi B, Pállinger É, Radovits T, Csulak E, Shenker-Horváth K, Kopper B, Buzás EI, Sydó N, Merkely B.
Publié dans: International Journal of Molecular Sciences, Numéro 14220067, 2022, ISSN 1422-0067
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Genomic Landscape of Normal and Breast Cancer Tissues in a Hungarian Pilot Cohort.

Auteurs: Pipek O, Alpár D, Rusz O, Bödör C, Udvarnoki Z, Medgyes-Horváth A, Csabai I, Szállási Z, Madaras L, Kahán Z, Cserni G, Kővári B, Kulka J, Tőkés AM.
Publié dans: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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Initial and ongoing tobacco smoking elicits vascular damage and distinct inflammatory response linked to neurodegeneration.

Auteurs: Garza AP, Morton L, Pállinger É, Buzás EI, Schreiber S, Schott BH, Dunay IR.
Publié dans: Brain, Behaviour and Immunity, 2023, ISSN 0889-1591
Éditeur: Academic Press
DOI: 10.1016/j.bbih.2023.100597

Lipids and Trehalose Actively Cooperate in Heat Stress Management of Schizosaccharomyces pombe.

Auteurs: Péter M, Gudmann P, Kóta Z, Török Z, Vígh L, Glatz A, Balogh G.
Publié dans: Journal of Molecular Sciences, 2021, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms222413272

Negative trade-off between neoantigen repertoire breadth and the specificity of HLA-I molecules shapes antitumor immunity

Auteurs: Máté Manczinger, Balázs Koncz, Gergő Mihály Balogh, Benjamin Tamás Papp, Leó Asztalos, Lajos Kemény, Balázs Papp, Csaba Pál
Publié dans: Nature Cancer, 2021, ISSN 2662-1347
Éditeur: Nature Research (subsidiary of Springer Nature)
DOI: 10.1038/s43018-021-00226-4

Complex treatment of residual metastatic germ cell cancer: A single center experience

Auteurs: Fruzsina Eszter Fazekas, Zsuzsanna Ujfaludi, Krisztina Biró, Zoltán Gábor Páhi, István Buzogány, Farkas Sükösd, Tibor Pankotai, Tamás Beöthe
Publié dans: Journal of Biotechnology, Numéro 389, 2024, Page(s) 61-67, ISSN 0168-1656
Éditeur: Elsevier BV
DOI: 10.1016/j.jbiotec.2024.04.018

Development and Functional Characterization of a Versatile Radio-/Immunotheranostic Tool for Prostate Cancer Management.

Auteurs: Arndt C, Bergmann R, Striese F, Merkel K, Máthé D, Loureiro LR, Mitwasi N, Kegler A, Fasslrinner F, González Soto KE, Neuber C, Berndt N, Kovács N, Szöllősi D, Hegedűs N, Tóth G, Emmermann J-P, Harikumar KB, Kovacs T, Bachmann M, Feldmann A.
Publié dans: Cancers, 2022, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14081996

Parallel testing of liquid biopsy (ctDNA) and tissue biopsy samples reveals a higher frequency of EZH2 mutations in follicular lymphoma.

Auteurs: Timár B, Csomor J, Tóth E, Schneider T, Mikala G, Matolcsy A, Alpár D, Masszi A, Bödör C.
Publié dans: Journal of Internal Medicine, 2023, ISSN 0954-6820
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/joim.13674

Intraperitoneal Glucose Transport to Micrometastasis: A Multimodal In Vivo Imaging Investigation in a Mouse Lymphoma Model

Auteurs: Zsombor Ritter, Katalin Zámbó, Xinkai Jia, Dávid Szöllősi, Dániel Dezső, Hussain Alizadeh, Ildikó Horváth, Nikolett Hegedűs, David Tuch, Kunal Vyas, Péter Balogh, Domokos Máthé, Erzsébet Schmidt
Publié dans: International Journal of Molecular Sciences, Numéro 22/9, 2021, Page(s) 4431, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22094431

β-Endorphin mediates radiation therapy fatigue.

Auteurs: Hermann AL, Fell GL, Kemény LV, Fung CY, Held KD, Biggs PJ, Rivera PD, Bilbo SD, Igras V, Willers H, Kung J, Gheorghiu L, Hideghéty K, Mao J, Woolf CJ, Fisher DE.
Publié dans: Science advances, 2022, ISSN 2375-2548
Éditeur: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abn6025

Anticancer Potential of L-Histidine-Capped Silver Nanoparticles against Human Cervical Cancer Cells (SiHA).

Auteurs: Mohammed Asik R, Manikkaraja C, Tamil Surya K, Suganthy N, Priya Aarthy A, Mathe D, Sivakumar M, Archunan G, Padmanabhan P, Gulyas B.
Publié dans: Nanomaterials, 2021, ISSN 2079-4991
Éditeur: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/nano11113154

Supraoptimal Iron Nutrition of Brassica napus Plants Suppresses the Iron Uptake of Chloroplasts by Down-Regulating Chloroplast Ferric Chelate Reductase

Auteurs: Máté Sági-Kazár, Helga Zelenyánszki, Brigitta Müller, Barnabás Cseh, Balázs Gyuris, Sophie Z. Farkas, Ferenc Fodor, Brigitta Tóth, Béla Kovács, Anna Koncz, Tamás Visnovitz, Edit I. Buzás, Barbara Bánkúti, Ferenc Bánáti, Kálmán Szenthe and Ádám Solti
Publié dans: Frontiers in Plant Science, 2021, Page(s) 12/748, ISSN 1664-462X
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fpls.2021.658987

Membrane Domain Localization and Interaction of the Prion-Family Proteins, Prion and Shadoo with Calnexin.

Auteurs: Dondapati DT, Cingaram PR, Ayaydin F, Nyeste A, Kanyó A, Welker E, Fodor E.
Publié dans: MDPI Membranes, 2021, ISSN 2077-0375
Éditeur: Molecular Diversity Preservation International
DOI: 10.3390/membranes11120978

A Photo-clickable ATP-Mimetic Reveals Nucleotide Interactors in the Membrane Proteome

Auteurs: Mark Jelcic, Ke Wang, King Lam Hui, Xiao-Chuan Cai, Balázs Enyedi, Minkui Luo, Philipp Niethammer
Publié dans: Cell Chemical Biology, Numéro 27/8, 2020, Page(s) 1073-1083.e12, ISSN 2451-9456
Éditeur: Elsevier Inc.
DOI: 10.1016/j.chembiol.2020.05.010

The effect of antifungal resistance development on the virulence of Candida species.

Auteurs: Bohner F, Papp C, Gácser A.
Publié dans: FEMS Yeast Research, 2022, ISSN 1567-1356
Éditeur: Blackwell
DOI: 10.1093/femsyr/foac019

Functionalized Mesoporous Silica Nanoparticles for Drug-Delivery to Multidrug-Resistant Cancer Cells.

Auteurs: Igaz N, Bélteky P, Kovács D, Papp C, Rónavári A, Szabó D, Gácser A, Kónya Z, Kiricsi M.
Publié dans: International Journal of Nanomedicine, 2022, ISSN 1176-9114
Éditeur: Dove Medical Press Ltd
DOI: 10.2147/ijn.s363952

Reorganization of the actin cytoskeleton during the formation of neutrophil extracellular traps (NETs).

Auteurs: Mannherz, H. G., Budde, H., Jarkas, M., Hassoun, R., Malek-Chudzik, N., Mazur, A. J., Skuljec, J., Pul, R., Napirei, M., & Hamdani, N.
Publié dans: European journal of cell biology, 2024, ISSN 0171-9335
Éditeur: Elsevier BV
DOI: 10.1016/j.ejcb.2024.151407

Thrombocytosis and Effects of IL-6 Knock-Out in a Colitis-Associated Cancer Model

Auteurs: Valeria Josa, Szilamer Ferenczi, Rita Szalai, Eniko Fuder, Daniel Kuti, Krisztina Horvath, Nikolett Hegedus, Tibor Kovacs, Gergo Bagamery, Balazs Juhasz, Zsuzsanna Winkler, Daniel S. Veres, Zsombor Zrubka, Domokos Mathe, Zsolt Baranyai
Publié dans: International Journal of Molecular Sciences, Numéro 21/17, 2020, Page(s) 6218, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21176218

Novel, clinically relevant genomic patterns identified by comprehensive genomic profiling in ATRX-deficient IDH-wildtype adult high-grade gliomas.

Auteurs: Bedics G, Szőke P, Bátai B, Nagy T, Papp G, Kránitz N, Rajnai H, Reiniger L, Bödör C, Scheich B.
Publié dans: Scienntific Reports, 2023, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-023-45786-w

CD44 Expression Intensity Marks Colorectal Cancer Cell Subpopulations with Different Extracellular Vesicle Release Capacity.

Auteurs: Kelemen A, Carmi I, Seress I, Lőrincz P, Tölgyes T, Dede K, Bursics A, Buzás EI, Wiener Z.
Publié dans: International journal of molecular sciences, 2022, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23042180

Balanced Intense Exercise Training Induces Atrial Oxidative Stress Counterbalanced by the Antioxidant System and Atrial Hypertrophy That Is Not Associated with Pathological Remodeling or Arrhythmogenicity

Auteurs: Attila Oláh, Bálint András Barta, Alex Ali Sayour, Mihály Ruppert, Eszter Virág-Tulassay, Julianna Novák, Zoltán V. Varga, Péter Ferdinandy, Béla Merkely, Tamás Radovits
Publié dans: Antioxidants, Numéro 10/3, 2021, Page(s) 452, ISSN 2076-3921
Éditeur: MDPI Multidisciplinary Digital Publishing Institute
DOI: 10.3390/antiox10030452

Self-mediated positive selection of T cells sets an obstacle to the recognition of nonself

Auteurs: Balázs Koncz, Gergő M. Balogh, Benjamin T. Papp, Leó Asztalos, Lajos Kemény, Máté Manczinger
Publié dans: Proceedings of the National Academy of Sciences, Numéro 118/37, 2021, Page(s) e2100542118, ISSN 0027-8424
Éditeur: National Academy of Sciences
DOI: 10.1073/pnas.2100542118

Reinstating olfactory bulb-derived limbic gamma oscillations alleviates depression-like behavioral deficits in rodents.

Auteurs: Li Q, Takeuchi Y, Wang J, Gellért L, Barcsai L, Pedraza LK, Nagy AJ, Kozák G, Nakai S, Kato S, Kobayashi K, Ohsawa M, Horváth G, Kékesi G, Lőrincz ML, Devinsky O, Buzsáki G, Berényi A.
Publié dans: Neuron, 2023, ISSN 1097-4199
Éditeur: Cell Press
DOI: 10.1016/j.neuron.2023.04.013

Impaired regulation of PMCA activity by defective CFTR expression promotes epithelial cell damage in alcoholic pancreatitis and hepatitis

Auteurs: Madácsy T, Varga Á, Papp N, Tél B, Pallagi P, Szabó V, Kiss A, Fanczal J, Rakonczay Z Jr, Tiszlavicz L, Rázga Z, Hohwieler M, Kleger A, Gray M, Hegyi P, Maléth J
Publié dans: Cellular and Molecular Life Sciences, 2022, ISSN 1420-682X
Éditeur: Birkhauser Verlag
DOI: 10.1007/s00018-022-04287-1

Lactobacillus acidophilus, L. plantarum, L. rhamnosus, and L. reuteri Cell-Free Supernatants Inhibit Candida parapsilosis Pathogenic Potential upon Infection of Vaginal Epithelial Cells Monolayer and in a Transwell Coculture System In Vitro.

Auteurs: Spaggiari L, Sala A, Ardizzoni A, De Seta F, Singh DK, Gacser A, Blasi E, Pericolini E.
Publié dans: Microbiology spectrum, 2022, ISSN 2165-0497
Éditeur: American Society for Microbiology
DOI: 10.1128/spectrum.02696-21

A single early introduction governed viral diversity in the second wave of SARS-CoV-2 epidemic in Hungary.

Auteurs: Ari E, Vásárhelyi BM, Kemenesi G, Tóth GE, Zana B, Somogyi B, Lanszki Z, Röst G, Jakab F, Papp B, Kintses B.
Publié dans: Virus Evolution, Numéro 20571577, 2022, ISSN 2057-1577
Éditeur: Oxford University Press
DOI: 10.1093/ve/veac069

Methods for the identification and characterization of extracellular vesicles in cardiovascular studies - from exosomes to microvesicles.

Auteurs: Davidson SM, Boulanger CM, Aikawa E, Badimon L, Barile L, Binder CJ, Brisson A, Buzas E, Emanueli C, Jansen F, Katsur M, Lacroix R, Lim SK, Mackman N, Mayr M, Menasché P, Nieuwland R, Sahoo S, Takov K, Thum T, Vader P, Wauben MHM, Witwer K, Sluijter JPG.
Publié dans: Cardiovascular Research, 2022, ISSN 1755-3245
Éditeur: Oxford University Press
DOI: 10.1093/cvr/cvac031

Chronic Exposure to the Food Additive tBHQ Modulates Expression of Genes Related to SARS-CoV-2 and Influenza Viruses.

Auteurs: Németh K, Petschner P, Pálóczi K, Fekete N, Pállinger É, Buzás EI, Tamási V.
Publié dans: Life, 2022, ISSN 2075-1729
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/life12050642

Functional characterization of the transient receptor potential melastatin 2 (TRPM2) cation channel from Nematostella vectensis reconstituted into lipid bilayer.

Auteurs: Szollosi A, Almássy J.
Publié dans: Scientific Reports, 2023, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-023-38640-6

Folate-Targeted Monodisperse PEG-Based Conjugates Made by Chemo-Enzymatic Methods for Cancer Diagnosis and Treatment

Auteurs: Krisztina S. Nagy, Krisztina Toth, Eva Pallinger, Angela Takacs, Laszlo Kohidai, Angela Jedlovszky-Hajdu, Domokos Mathe, Noemi Kovacs, Daniel S. Veres, Krisztian Szigeti, Kristof Molnar, Eniko Krisch, Judit E. Puskas
Publié dans: International Journal of Molecular Sciences, Numéro 22/19, 2021, Page(s) 10347, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms221910347

Higher-order thalamic nuclei facilitate the generalization and maintenance of spike-and-wave discharges of absence seizures.

Auteurs: Atherton Z, Nagy O, Barcsai L, Sere P, Zsigri N, Földi T, Gellért L, Berényi A, Crunelli V, Lőrincz ML.
Publié dans: Neurobiology of Disease, 2023, ISSN 0969-9961
Éditeur: Academic Press
DOI: 10.1016/j.nbd.2023.106025

Signaling through Syk or CARD9 Mediates Species-Specific Anti- Candida Protection in Bone Marrow Chimeric Mice

Auteurs: Erik Zajta, Katalin Csonka, Adél Tóth, Laszló Tiszlavicz, Tamás Németh, Anita Orosz, Ádám Novák, Máté Csikós, Csaba Vágvölgyi, Attila Mócsai, Attila Gácser
Publié dans: mBio, Numéro 12/4, 2021, ISSN 2150-7511
Éditeur: American Society for Microbiology
DOI: 10.1128/mbio.01608-21

Integrated evolutionary analysis reveals antimicrobial peptides with limited resistance

Auteurs: Réka Spohn, Lejla Daruka, Viktória Lázár, Ana Martins, Fanni Vidovics, Gábor Grézal, Orsolya Méhi, Bálint Kintses, Mónika Számel, Pramod K. Jangir, Bálint Csörgő, Ádám Györkei, Zoltán Bódi, Anikó Faragó, László Bodai, Imre Földesi, Diána Kata, Gergely Maróti, Bernadett Pap, Roland Wirth, Balázs Papp, Csaba Pál
Publié dans: Nature Communications, Numéro 10/1, 2019, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-019-12364-6

Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action

Auteurs: Bálint Kintses, Pramod K. Jangir, Gergely Fekete, Mónika Számel, Orsolya Méhi, Réka Spohn, Lejla Daruka, Ana Martins, Ali Hosseinnia, Alla Gagarinova, Sunyoung Kim, Sadhna Phanse, Bálint Csörgő, Ádám Györkei, Eszter Ari, Viktória Lázár, István Nagy, Mohan Babu, Csaba Pál, Balázs Papp
Publié dans: Nature Communications, Numéro 10/1, 2019, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-019-13618-z

Unmatched level of molecular convergence among deeply divergent complex multicellular fungi

Auteurs: Zsolt Merényi, Arun N Prasanna, Zheng Wang, Károly Kovács, Botond Hegedüs, Balázs Bálint, Balázs Papp, Jeffrey P Townsend, László G Nagy
Publié dans: Molecular Biology and Evolution, 2020, ISSN 0737-4038
Éditeur: Oxford University Press
DOI: 10.1093/molbev/msaa077

Rapid decline of bacterial drug-resistance in an antibiotic-free environment through phenotypic reversion

Auteurs: Anett Dunai, Réka Spohn, Zoltán Farkas, Viktória Lázár, Ádám Györkei, Gábor Apjok, Gábor Boross, Balázs Szappanos, Gábor Grézal, Anikó Faragó, László Bodai, Balázs Papp, Csaba Pál
Publié dans: eLife, 2019, ISSN 2050-084X
Éditeur: eLife Sciences Publications
DOI: 10.7554/elife.47088.001

Activity-based protein profiling of the human failing ischemic heart reveals alterations in hydrolase activities involving the endocannabinoid system

Auteurs: Annelot C.M. van Esbroeck, Zoltan V. Varga, Xinyu Di, Eva J. van Rooden, Viktória E. Tóth, Zsófia Onódi, Mariusz Kuśmierczyk, Przemyslaw Leszek, Péter Ferdinandy, Thomas Hankemeier, Mario van der Stelt, Pál Pacher
Publié dans: Pharmacological Research, Numéro 151, 2020, Page(s) 104578, ISSN 1043-6618
Éditeur: Academic Press
DOI: 10.1016/j.phrs.2019.104578

Extracellular vesicles transmit epithelial growth factor activity in the intestinal stem cell niche

Auteurs: Ádám Oszvald, Zsuzsanna Szvicsek, Gyöngyvér Orsolya Sándor, Andrea Kelemen, András Áron Soós, Krisztina Pálóczi, Attila Bursics, Kristóf Dede, Tamás Tölgyes, Edit I. Buzás, Anikó Zeöld, Zoltán Wiener
Publié dans: STEM CELLS, 2019, ISSN 1066-5099
Éditeur: AlphaMed Press Inc
DOI: 10.1002/stem.3113

Unravelling the Role of Trophoblastic-Derived Extracellular Vesicles in Regulatory T Cell Differentiation

Auteurs: Árpád Ferenc Kovács, Nóra Fekete, Lilla Turiák, András Ács, László Kőhidai, Edit I. Buzás, Éva Pállinger
Publié dans: International Journal of Molecular Sciences, Numéro 20/14, 2019, Page(s) 3457, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20143457

Cartilage Oligomeric Matrix Protein Negatively Influences Keratinocyte Proliferation Via α5β1-Integrin: Potential Relevance of Altered Cartilage Oligomeric Matrix Protein Expression in Psoriasis

Auteurs: Renáta Bozó, Edit Szél, Judit Danis, Barbara Gubán, Zsuzsanna Bata-Csörgő, Kornélia Szabó, Lajos Kemény, Gergely Groma
Publié dans: Journal of Investigative Dermatology, 2020, ISSN 0022-202X
Éditeur: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2019.12.037

Comprehensive Proteomic Analysis Reveals Intermediate Stage of Non-Lesional Psoriatic Skin and Points out the Importance of Proteins Outside this Trend

Auteurs: Edit Szél, Renáta Bozó, Éva Hunyadi-Gulyás, Máté Manczinger, Kornélia Szabó, Lajos Kemény, Zsuzsanna Bata-Csörgő, Gergely Groma
Publié dans: Scientific Reports, Numéro 9/1, 2019, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-019-47774-5

Targeting the gut‐skin axis—Probiotics as new tools for skin disorder management?

Auteurs: Magdolna Szántó, Anikó Dózsa, Dóra Antal, Kornélia Szabó, Lajos Kemény, Péter Bai
Publié dans: Experimental Dermatology, Numéro 28/11, 2019, Page(s) 1210-1218, ISSN 0906-6705
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/exd.14016

Exploring the fitness benefits of genome reduction in Escherichia coli by a selection-driven approach

Auteurs: Viktor Vernyik, Ildikó Karcagi, Edit Tímár, István Nagy, Ádám Györkei, Balázs Papp, Zsuzsanna Györfy, György Pósfai
Publié dans: Scientific Reports, Numéro 10/1, 2020, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-020-64074-5

Multilevel structure–activity profiling reveals multiple green tea compound families that each modulate ubiquitin-activating enzyme and ubiquitination by a distinct mechanism

Auteurs: Gabriel Fenteany, Paras Gaur, Lili Hegedűs, Kata Dudás, Ernő Kiss, Edit Wéber, László Hackler, Tamás Martinek, László G. Puskás, Lajos Haracska
Publié dans: Scientific Reports, Numéro 9/1, 2019, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-019-48888-6

Robust high-throughput assays to assess discrete steps in ubiquitination and related cascades

Auteurs: Gabriel Fenteany, Paras Gaur, Gaurav Sharma, Lajos Pintér, Ernő Kiss, Lajos Haracska
Publié dans: BMC Molecular and Cell Biology, Numéro 21/1, 2020, ISSN 2661-8850
Éditeur: Springer Nature
DOI: 10.1186/s12860-020-00262-5

The Role of P2X7 Receptor in Alzheimer’s Disease

Auteurs: Linda Francistiová, Carolina Bianchi, Caterina Di Lauro, Álvaro Sebastián-Serrano, Laura de Diego-García, Julianna Kobolák, András Dinnyés, Miguel Díaz-Hernández
Publié dans: Frontiers in Molecular Neuroscience, Numéro 13, 2020, ISSN 1662-5099
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fnmol.2020.00094

Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System

Auteurs: Kinga Tóth, Dorottya Ádám, Tamás Bíró, Attila Oláh
Publié dans: Molecules, Numéro 24/5, 2019, Page(s) 918, ISSN 1420-3049
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules24050918

Nicotinic acid suppresses sebaceous lipogenesis of human sebocytes via activating hydroxycarboxylic acid receptor 2 (HCA 2 )

Auteurs: Arnold Markovics, Kinga Fanni Tóth, Katalin Eszter Sós, József Magi, Adrienn Gyöngyösi, Zoltán Benyó, Christos C. Zouboulis, Tamás Bíró, Attila Oláh
Publié dans: Journal of Cellular and Molecular Medicine, Numéro 23/9, 2019, Page(s) 6203-6214, ISSN 1582-1838
Éditeur: Wiley-Blackwell
DOI: 10.1111/jcmm.14505

Advances in the optimisation of therapeutic drug monitoring using serum, tissue and faecal anti-tumour necrosis factor concentration in patients with inflammatory bowel disease treated with TNF-α antagonists

Auteurs: Kata Judit Szántó, Tamara Madácsy, Diána Kata, Tamás Ferenci, Mariann Rutka, Anita Bálint, Renáta Bor, Anna Fábián, Ágnes Milassin, Boldizsár Jójárt, Zoltán Szepes, Ferenc Nagy, Tamás Molnár, Imre Földesi, József Maléth & Klaudia Farkas
Publié dans: Expert Opinion on Biological Therapy, 2021, ISSN 1744-7682
Éditeur: Taylor & Francis Ltd.
DOI: 10.1080/14712598.2021.1890712

Myelofibrosis progression grading based on type-I and type-III collagen and fibrillin-1 expression boosted by whole slide image analysis.

Auteurs: Szekely T, Wichmann B, Maros ME, Csizmadia A, Bodor C, Timar B, Krenacs T.
Publié dans: Histopathology, Numéro 03090167, 2022, ISSN 0309-0167
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/his.14846

Optimization of the Heterologous Expression of the Cannabinoid Type-1 (CB1) Receptor

Auteurs: Viktória B. Horváth, Eszter Soltész-Katona, Éva Wisniewski, Anikó Rajki, Eszter Halász, Balázs Enyedi, László Hunyady, András Dávid Tóth, Gergő Szanda
Publié dans: Frontiers in Endocrinology, Numéro 12, 2021, ISSN 1664-2392
Éditeur: Frontiers Media S.A.
DOI: 10.3389/fendo.2021.740913

Acquired Triazole Resistance Alters Pathogenicity-Associated Features in Candida auris in an Isolate-Dependent Manner.

Auteurs: Bohner F, Papp C, Takacs T, Varga M, Szekeres A, Nosanchuk JD, Vágvölgyi C, Tóth R, Gacser A.
Publié dans: Journal of Fungi, 2023, ISSN 2309-608X
Éditeur: MDPI
DOI: 10.3390/jof9121148

Phenol-Soluble Modulin α3 Stimulates Autophagy in HaCaT Keratinocytes.

Auteurs: Dernovics Á, Seprényi G, Rázga Z, Ayaydin F, Veréb Z, Megyeri K.
Publié dans: Biomedicines, 2023, ISSN 2227-9059
Éditeur: MDPI
DOI: 10.3390/biomedicines11113018

Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells

Auteurs: Markus Breunig, Jessica Merkle, Martin Wagner, Michael K. Melzer, Thomas F.E. Barth, Thomas Engleitner, Johannes Krumm, Sandra Wiedenmann, Christian M. Cohrs, Lukas Perkhofer, Gaurav Jain, Jana Krüger, Patrick C. Hermann, Maximilian Schmid, Tamara Madácsy, Árpád Varga, Joscha Griger, Ninel Azoitei, Martin Müller, Oliver Wessely, Pamela G. Robey, Sandra Heller, Zahra Dantes, Maximilian Reicher
Publié dans: Cell Stem Cell, 2021, ISSN 1934-5909
Éditeur: Cell Press
DOI: 10.1016/j.stem.2021.03.005

Author Correction: Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling

Auteurs: Eric Schoger, Federico Bleckwedel, Giulia Germena, Cheila Rocha, Petra Tucholla, Izzatullo Sobitov, Wiebke Möbius, Maren Sitte, Christof Lenz, Mostafa Samak, Rabea Hinkel, Zoltán V. Varga, Zoltán Giricz, Gabriela Salinas, Julia C. Gross, Laura C. Zelarayán
Publié dans: Communications Biology, Numéro 7, 2024, ISSN 2399-3642
Éditeur: Springer Nature
DOI: 10.1038/s42003-024-06319-x

Histone and Histone Acetylation-Related Alterations of Gene Expression in Uninvolved Psoriatic Skin and Their Effects on Cell Proliferation, Differentiation, and Immune Responses.

Auteurs: Romhányi D, Szabó K, Kemény L, Groma G.
Publié dans: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms241914551

Development of a Large-Scale Pathogen Screening Test for the Biosafety Evaluation of Canine Mesenchymal Stem Cells.

Auteurs: Pekker E, Priskin K, Szabó-Kriston É, Csányi B, Buzás-Bereczki O, Adorján L, Szukacsov V, Pintér L, Rusvai M, Cooper P, Kiss-Tóth E, Haracska L.
Publié dans: Biological Procedures Online, 2023, ISSN 1480-9222
Éditeur: BioMed Central
DOI: 10.1186/s12575-023-00226-x

No beneficial use of the wearable cardioverter defibrillator among patients suffering from inherited and congenital heart disease: data from a European multicenter registry

Auteurs: Katharina Koepsel, Tobias C. Dreher, Christian Blockhaus, Michael Gotzmann, Norbert Klein, Thomas Kuntz, Dong-In Shin, Hendrik Lapp, Fabian Schiedat, Mohammad Abumayyaleh, Thomas Beiert, Christian Weth, Boldizsar Kovacs, Stephanie Rosenkaimer, Jacqueline Kowitz, Ardan Muammer Saguner, Julia W. Erath, Firat Duru, Andreas Mügge, Ibrahim Akin, Assem Aweimer, Nazha Hamdani, Ibrahim El-Battrawy
Publié dans: Frontiers in Cardiovascular Medicine, Numéro 11, 2024, ISSN 2297-055X
Éditeur: Frontiers Media SA
DOI: 10.3389/fcvm.2024.1384736

Cardiac miRNA Expression and their mRNA Targets in a Rat Model of Prediabetes

Auteurs: Éva Sághy, Imre Vörös, Bence Ágg, Bernadett Kiss, Gábor Koncsos, Zoltán V. Varga, Anikó Görbe, Zoltán Giricz, Rainer Schulz, Péter Ferdinandy
Publié dans: International Journal of Molecular Sciences, Numéro 21/6, 2020, Page(s) 2128, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21062128

Nodular fasciitis: a comprehensive, time-correlated investigation of 17 cases

Auteurs: Zoltán Sápi, Zoltán Lippai, Gergő Papp, Lajos Hegyi, Johanna Sápi, Katalin Dezső, Károly Szuhai
Publié dans: Modern Pathology, 2021, ISSN 0893-3952
Éditeur: Nature Publishing Group
DOI: 10.1038/s41379-021-00883-x

The Wisdom in Teeth: Neuronal Differentiation of Dental Pulp Cells.

Auteurs: Sramkó B, Földes A, Kádár K, Varga G, Zsembery Á, Pircs K.
Publié dans: Cellular Reprogramming, 2023, ISSN 2152-4971
Éditeur: Mary Ann Liebert Inc.
DOI: 10.1089/cell.2022.0102

A complete nicotinate degradation pathway in the microbial eukaryote Aspergillus nidulans.

Auteurs: Bokor E, Ámon J, Varga M, Szekeres A, Hegedűs Z, Jakusch T, Szakonyi Z, Flipphi M, Vágvölgyi C, Gácser A, Scazzocchio C, Hamari Z.
Publié dans: Communications Biology, 2022, ISSN 2399-3642
Éditeur: Springer Nature
DOI: 10.1038/s42003-022-03684-3

Periodontitis: a newly identified comorbidity in psoriasis and psoriatic arthritis

Auteurs: Szandra Dalmády, Lajos Kemény, Márk Antal, Rolland Gyulai
Publié dans: Expert Review of Clinical Immunology, Numéro 16/1, 2020, Page(s) 101-108, ISSN 1744-666X
Éditeur: Future Drugs Ltd.
DOI: 10.1080/1744666x.2019.1700113

An Implantable Magneto-Responsive Poly(aspartamide) Based Electrospun Scaffold for Hyperthermia Treatment.

Auteurs: Veres T, Voniatis C, Molnár K, Nesztor D, Fehér D, Ferencz A, Gresits I, Thuróczy G, Márkus BG, Simon F, Nemes NM, García-Hernández M, Reiniger L, Horváth I, Máthé D, Szigeti K, Tombácz E, Jedlovszky-Hajdu A.
Publié dans: Nanomaterials, 2022, ISSN 2079-4991
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nano12091476

Reduced MC4R signaling alters nociceptive thresholds associated with red hair

Auteurs: Kathleen C. Robinson, Lajos V. Kemény, Gillian L. Fell, Andrea L. Hermann, Jennifer Allouche, Weihua Ding, Ajay Yekkirala, Jennifer J. Hsiao, Mack Y. Su, Nicholas Theodosakis, Gabor Kozak, Yuichi Takeuchi, Shiqian Shen, Antal Berenyi, Jianren Mao, Clifford J. Woolf, David E. Fisher
Publié dans: Science Advances, Numéro 7/14, 2021, Page(s) eabd1310, ISSN 2375-2548
Éditeur: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abd1310

Nanoinjection of extracellular vesicles to single live cells by robotic fluidic force microscopy.

Auteurs: Kovács KD, Visnovitz T, Gerecsei T, Peter B, Kurunczi S, Koncz A, Németh K, Lenzinger D, Vukman KV, Balogh A, Rajmon I, Lőrincz P, Székács I, Buzás EI, Horvath R.
Publié dans: Journal of Extracellular Vesicles, 2023, ISSN 2001-3078
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/jev2.12388

Virulence Factors and in-Host Selection on Phenotypes in Infectious Probiotic Yeast Isolates (Saccharomyces ‘boulardii’)

Auteurs: Alexandra Imre, Renátó Kovács, Kitti Pázmándi, Dániel Nemes, Ágnes Jakab, Tünde Fekete, Hanna Viktória Rácz, Ilona Dóczi, Ildikó Bácskay, Attila Gácser, Károly Kovács, László Majoros, Zoltán Farkas, István Pócsi, Walter P. Pfliegler
Publié dans: Journal of Fungi, Numéro 7/9, 2021, Page(s) 746, ISSN 2309-608X
Éditeur: Journal of Fungi
DOI: 10.3390/jof7090746

In situ lymphoma imaging in a spontaneous mouse model using the Cerenkov Luminescence of F-18 and Ga-67 isotopes.

Auteurs: Ritter, Z., Zámbó, K., Balogh, P., Szöllösi, D., Xinkai, J., Balázs, Á., Taba, G., Dezső, D., Horváth, I., Hussain, A., Tuch, D., Vyas, K., Hegedűs, N., Kovács, T., Szigeti, K., Máthé D.,Schmidt, E.
Publié dans: Scientific reports, 2021, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-021-03505-3

High fat diet and PCSK9 knockout modulates lipid profile of the liver and changes the expression of lipid homeostasis related genes.

Auteurs: Németh K, Tóth B, Sarnyai F, Koncz A, Lenzinger D, Kereszturi É, Visnovitz T, Kestecher BM, Osteikoetxea X, Csala M, Buzás EI, Tamási V.
Publié dans: Nutrition and Metabolism, 2023, ISSN 1743-7075
Éditeur: BioMed Central
DOI: 10.1186/s12986-023-00738-z

Epigenetic Mechanisms of ART-Related Imprinting Disorders: Lessons from iPSC and Mouse Models

Auteurs: Alex Horánszky, Jessica L. Becker, Melinda Zana, Anne C. Ferguson-Smith, András Dinnyés
Publié dans: Genes, Numéro 12/11, 2021, Page(s) 1704, ISSN 2073-4425
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes12111704

Potential role of MAP2K1 mutation in the trans-differentiation of interdigitating dendritic cell sarcoma: Case report and literature review.

Auteurs: Jenei A, Bedics G, Erdélyi DJ, Müller J, Györke T, Bödör C, Szepesi Á.
Publié dans: Frontiers in Pediatrics, Numéro 22962360, 2022, ISSN 2296-2360
Éditeur: Frontiers Media S.A.
DOI: 10.3389/fped.2022.959307

Droplet Digital PCR Is a Novel Screening Method Identifying Potential Cardiac G-Protein-Coupled Receptors as Candidate Pharmacological Targets in a Rat Model of Pressure-Overload-Induced Cardiac Dysfunction.

Auteurs: Sayour NV, Tóth VÉ, Nagy RN, Vörös I, Gergely TG, Onódi Z, Nagy N, Bödör C, Váradi B, Ruppert M, Radovits T, Bleckwedel F, Zelarayán LC, Pacher P, Ágg B, Görbe A, Ferdinandy P, Varga ZV. Droplet
Publié dans: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms241813826

Spinocerebellar Ataxia in a Hungarian Female Patient with a Novel Variant of Unknown Significance in the CCDC88C Gene.

Auteurs: Boros FA, Szpisjak L, Bozó R, Kelemen E, Zádori D, Salamon A, Danis J, Kalmár T, Maróti Z, Molnár MJ, Klivényi P, Széll M, Ádám É.
Publié dans: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24032617

NASH triggers cardiometabolic HFpEF in aging mice.

Auteurs: Kucsera, D., Ruppert, M., Sayour, N. V., Tóth, V. E., Kovács, T., Hegedűs, Z. I., Onódi, Z., Fábián, A., Kovács, A., Radovits, T., Merkely, B., Pacher, P., Ferdinandy, P., & Varga, Z. V.
Publié dans: GeroScience, 2024, ISSN 2509-2715
Éditeur: Springer Science and Business Media Deutschland GmbH
DOI: 10.1007/s11357-024-01153-9

Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan.

Auteurs: Correia-Melo C, Kamrad S, Tengölics R, Messner CB, Trebulle P, Townsend S, Jayasree Varma S, Freiwald A, Heineike BM, Campbell K, Herrera-Dominguez L, Kaur Aulakh S, Szyrwiel L, Yu JSL, Zelezniak A, Demichev V, Mülleder M, Papp B, Alam MT, Ralser M.
Publié dans: Cell, 2023, ISSN 0092-8674
Éditeur: Cell Press
DOI: 10.1016/j.cell.2022.12.007

A dual role of lysophosphatidic acid type 2 receptor (LPAR2) in nonsteroidal anti-inflammatory drug-induced mouse enteropathy.

Auteurs: Hutka B, Várallyay A, László SB, Tóth AS, Scheich B, Paku S, Vörös I, Pós Z, Varga ZV, Norman DD, Balogh A, Benyó Z, Tigyi G, Gyires K, Zádori ZS.
Publié dans: Acta Pharmacologica Sinica, 2023, ISSN 1671-4083
Éditeur: Shanghai Institute of Materia Medica
DOI: 10.1038/s41401-023-01175-7

Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility.

Auteurs: White R, Sotillo J, Ancarola ME, Borup A, Boysen AT, Brindley PJ, Buzás EI, Cavallero S, Chaiyadet S, Chalmers IW, Cucher MA, Dagenais M, Davis CN, Devaney E, Duque-Correa MA, Eichenberger RM, Fontenla S, Gasan TA, Hokke CH, Kosanovic M, Kuipers ME, Laha T, Loukas A, Maizels RM, Marcilla A, Mazanec H, Morphew RM, Neophytou K, Nguyen LT, Nolte-'t Hoen E, Povelones M, Robinson MW, Rojas A, Schabuss
Publié dans: Journal of Extracellular Vesicles, 2023, ISSN 2001-3078
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/jev2.12298

Transcriptome and proteome profiling reveals complex adaptations of Candida parapsilosis cells assimilating hydroxyaromatic carbon sources.

Auteurs: Cillingová A, Tóth R, Mojáková A, Zeman I, Vrzoňová R, Siváková B, Baráth P, Neboháčová M, Klepcová Z, Brázdovič F, Lichancová H, Hodorová V, Brejová B, Vinař T, Mutalová S, Vozáriková V, Mutti G, Tomáška Ľ, Gácser A, Gabaldón T, Nosek J.
Publié dans: Plos Genetics, 2022, ISSN 1553-7390
Éditeur: Public Library of Science
DOI: 10.1371/journal.pgen.1009815

Cross-Linking Mass Spectrometry on P-Glycoprotein.

Auteurs: Gellen G, Klement E, Biwott K, Schlosser G, Kalló G, Csősz É, Medzihradszky KF, Bacso Z.
Publié dans: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms241310627

Erratum to: P459 Expression of SerpinE1, a potential new disease activity marker, reflects therapeutic response in Inflammatory Bowel Disease.

Auteurs: Jójárt B, Molnàr T, Szabó V, Varga Á, Resàl T, Szàntó K, Kata D, Földesi I, Molnár T, Maléth J, Farkas K.
Publié dans: Journal of Chron's and colitis, 2021, ISSN 1873-9946
Éditeur: Elsevier Science
DOI: 10.1093/ecco-jcc/jjab160

The psoriatic non-lesional skin: a battlefield of constant fight between susceptibility and protective factors

Auteurs: Evelyn Kelemen, Renáta Bozó, Gergely Groma, Zsuzsanna Bata-Csörgő, Lajos Kemény, Judit Danis, Márta Széll
Publié dans: Journal of Investigative Dermatology, 2021, ISSN 0022-202X
Éditeur: Blackwell Publishing Inc.
DOI: 10.1016/j.jid.2021.05.020

In planta test system for targeted cellular mutagenesis by injection of oligonucleotides to apical meristem of maize seedlings

Auteurs: Feríz Rádi, Bettina Nagy, Györgyi Ferenc, Katalin Török, István Nagy, Zoltán Zombori, Dénes Dudits, Ferhan Ayaydin
Publié dans: Acta Physiologiae Plantarum, Numéro 43/5, 2021, ISSN 0137-5881
Éditeur: Agencja Wydawnicza ARIES
DOI: 10.1007/s11738-021-03252-y

Small extracellular vesicle DNA-mediated horizontal gene transfer as a driving force for tumor evolution: Facts and riddles.

Auteurs: Valcz G, Újvári B, Buzás EI, Krenács T, Spisák S, Kittel Á, Tulassay Z, Igaz P, Takács I, Molnár B.
Publié dans: Frontiers in Oncology, 2022, ISSN 2234-943X
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.945376

The Utilization of Physiologically Active Molecular Components of Grape Seeds and Grape Marc.

Auteurs: Hegedüs I, Andreidesz K, Szentpéteri JL, Kaleta Z, Szabó L, Szigeti K, Gulyás B, Padmanabhan P, Budan F, Máthé D.
Publié dans: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms231911165

Nod-Like Receptors in Host Defence and Disease at the Epidermal Barrier

Auteurs: Judit Danis, Mark Mellett
Publié dans: International Journal of Molecular Sciences, Numéro 22/9, 2021, Page(s) 4677, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22094677

Donor Pericardial Interleukin and Apolipoprotein Levels May Predict the Outcome after Human Orthotopic Heart Transplantation.

Auteurs: Pállinger É, Székely A, Töreki E, Bencsáth EZ, Szécsi B, Losoncz E, Oleszka M, Hüttl T, Kosztin A, Buzas EI, Radovits T, Merkely B.
Publié dans: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24076780

The DREAM complex represses growth in response to DNA damage in Arabidopsis

Auteurs: Lucas Lang, Aladár Pettkó-Szandtner, Hasibe Tunçay Elbaşı, Hirotomo Takatsuka, Yuji Nomoto, Ahmad Zaki, Stefan Dorokhov, Geert De Jaeger, Dominique Eeckhout, Masaki Ito, Zoltán Magyar, László Bögre, Maren Heese, Arp Schnittger
Publié dans: Life Science Alliance, Numéro 4/12, 2021, Page(s) e202101141, ISSN 2575-1077
Éditeur: Life Science Alliance
DOI: 10.26508/lsa.202101141

Microbiome's Universe: Impact on health, disease and cancer treatment

Auteurs: Zsuzsánna Réthi-Nagy, Szilvia Juhász
Publié dans: Journal of Biotechnology, Numéro 392, 2024, Page(s) 161-179, ISSN 0168-1656
Éditeur: Elsevier BV
DOI: 10.1016/j.jbiotec.2024.07.002

Prognostic potential of CUL3 ligase with differential roles in luminal A and basal type breast cancer tumors

Auteurs: Vasiliki Pantazi, Vanda Miklós, Paul Smith, Orsolya Oláh-Németh, Gabriella Pankotai-Bodó, Divya Teja Dondapati, Ferhan Ayaydin, Vincenzo D’Angiolella, Tibor Pankotai
Publié dans: Scientific Reports, Numéro 14, 2024, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-024-65692-z

Synthesis and preclinical application of a Prussian blue-based dual fluorescent and magnetic contrast agent (CA).

Auteurs: Hegedűs N, Forgách L, Kiss B, Varga Z, Jezsó B, Horváth I, Kovács N, Hajdrik P, Padmanabhan P, Gulyás B, Szigeti K, Máthé D.
Publié dans: Plos One, 2022, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0264554

Psoriatic Resolved Skin Epidermal Keratinocytes Retain Disease-Residual Transcriptomic and Epigenomic Profiles.

Auteurs: Ghaffarinia A, Ayaydin F, Póliska S, Manczinger M, Bolla BS, Flink LB, Balogh F, Veréb Z, Bozó R, Szabó K, Bata-Csörgő Z, Kemény L.
Publié dans: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24054556

Engineered Cas9 extracellular vesicles as a novel gene editing tool.

Auteurs: Osteikoetxea X, Silva A, Lázaro-Ibáñez E, Salmond N, Shatnyeva O, Stein J, Schick J, Wren S, Lindgren J, Firth M, Madsen A, Mayr LM, Overman R, Davies R, Dekker N.
Publié dans: Extracell Vesicles, 2022, ISSN 2001-3078
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/jev2.12225

Non-coding Natural Antisense Transcripts: Analysis and Application

Auteurs: Julian C. Krappinger, Lilli Bonstingl, Katrin Pansy, Katja Sallinger, Nick I. Wreglesworth, Lukas Grinninger, Alexander Deutsch, Amin El-Heliebi, Thomas Kroneis, Ramsay J. Mcfarlane, Christoph W. Sensen, Julia Feichtinger
Publié dans: Journal of Biotechnology, 2021, ISSN 0168-1656
Éditeur: Elsevier BV
DOI: 10.1016/j.jbiotec.2021.08.005

Optimization of CFTR gating through the evolution of its extracellular loops.

Auteurs: Simon MA, Csanády L.
Publié dans: Journal of General Physiology, 2023, ISSN 0022-1295
Éditeur: Rockefeller University Press
DOI: 10.1085/jgp.202213264

Circulating cardiomyocyte-derived extracellular vesicles reflect cardiac injury during systemic inflammatory response syndrome in mice.

Auteurs: Hegyesi H, Pallinger É, Mecsei S, Hornyák B, Kovácsházi C, Brenner GB, Giricz Z, Pálóczi K, Kittel Á, Tóvári J, Turiak L, Khamari D, Ferdinandy P, Buzás EI.
Publié dans: Cellular and Molecular Life Sciences, 2022, ISSN 1431-1941
Éditeur: Springer Nature
DOI: 10.1007/s00018-021-04125-w

Small paraquat resistance proteins modulate paraquat and ABA responses and confer drought tolerance to overexpressing Arabidopsis plants.

Auteurs: Faragó D, Zsigmond L, Benyó D, Alcazar R, Rigó G, Ayaydin F, Rabilu SA, Hunyadi-Gulyás É, Szabados L
Publié dans: Plant, Cell and Environment, 2022, ISSN 0140-7791
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/pce.14338

Heavy metals in cigarette smoke strongly inhibit pancreatic ductal function and promote development of chronic pancreatitis

Auteurs: Petra Pallagi, Emese Tóth, Marietta Görög, Viktória Venglovecz, Tamara Madácsy, Árpád Varga, Tünde Molnár, Noémi Papp, Viktória Szabó, Enikő Kúthy‐Sutus, Réka Molnár, Attila Ördög, Katalin Borka, Andrea Schnúr, Albert Kéri, Gyula Kajner, Kata Csekő, Emese Ritter, Dezső Csupor, Zsuzsanna Helyes, Gábor Galbács, Andrea Szentesi, László Czakó, Zoltán Rakonczay, Tamás Tak
Publié dans: Clinical and Translational Medicine, Numéro 14, 2024, ISSN 2001-1326
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/ctm2.1733

Widespread alterations in microRNA biogenesis in human Huntington's disease putamen.

Auteurs: Petry S, Keraudren R, Nateghi B, Loiselle A, Pircs K, Jakobsson J, Sephton C, Langlois M, St-Amour I, Hébert SS.
Publié dans: Acta neuropathologica communications, 2022, ISSN 2051-5960
Éditeur: BioMed Central
DOI: 10.1186/s40478-022-01407-7

Predictive Potential of RNA Polymerase B (II) Subunit 1 (RPB1) Cytoplasmic Aggregation for Neoadjuvant Chemotherapy Failure.

Auteurs: Nagy-Mikó B, Németh-Szatmári O, Faragó-Mészáros R, Csókási A, Bognár B, Ördög N, Borsos BN, Majoros H, Ujfaludi Z, Oláh-Németh O, Nikolényi A, Dobi Á, Kószó R, Sántha D, Lázár G, Simonka Z, Paszt A, Ormándi K, Pankotai T, Boros IM, Villányi Z, Vörös A.
Publié dans: International Journel of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242115869

Limited Evolutionary Conservation of the Phenotypic Effects of Antibiotic Resistance Mutations

Auteurs: Gábor Apjok, Gábor Boross, Ákos Nyerges, Gergely Fekete, Viktória Lázár, Balázs Papp, Csaba Pál, Bálint Csörgő
Publié dans: Molecular Biology and Evolution, Numéro 36/8, 2019, Page(s) 1601-1611, ISSN 0737-4038
Éditeur: Oxford University Press
DOI: 10.1093/molbev/msz109

Genetic Characterization of Primary Mediastinal B-Cell Lymphoma: Pathogenesis and Patient Outcomes.

Auteurs: Noerenberg D, Briest F, Hennch C, Yoshida K, Hablesreiter R, Takeuchi Y, Ueno H, Staiger AM, Ziepert M, Asmar F, Locher BN, Toth E, Weber T, Amini RM, Klapper W, Bouzani M, Poeschel V, Rosenwald A, Held G, Campo E, Ishaque N, Stamatopoulos K, Kanellis G, Anagnostopoulos I, Bullinger L, Goldschmidt N, Zinzani PL, Bödör C, Rosenquist R, Vassilakopoulos TP, Ott G, Ogawa S, Damm F.
Publié dans: Journal of Clinical Oncology, 2023, ISSN 1527-7755
Éditeur: Lippincott Williams and Wilkins Ltd.
DOI: 10.1200/jco.23.01053

Identifying Suitable Reference Gene Candidates for Quantification of DNA Damage-Induced Cellular Responses in Human U2OS Cell Culture System.

Auteurs: Barta N, Ördög N, Pantazi V, Berzsenyi I, Borsos BN, Majoros H, Páhi ZG, Ujfaludi Z, Pankotai T.
Publié dans: Biomolecules, 2023, ISSN 2218-273X
Éditeur: MDPI
DOI: 10.3390/biom13101523

Profiling of Copy Number Alterations Using Low-Coverage Whole-Genome Sequencing Informs Differential Diagnosis and Prognosis in Primary Cutaneous Follicle Center Lymphoma.

Auteurs: Bátai, B., Kiss, L., Varga, L., Nagy, Á., Househam, J., Baker, A. M., László, T., Udvari, A., Horváth, R., Nagy, T., Csomor, J., Szakonyi, J., Schneider, T., Graham, T. A., Alpár, D., Fitzgibbon, J., Szepesi, Á., & Bödör, C.
Publié dans: Modern pathology, 2024, ISSN 0893-3952
Éditeur: Nature Publishing Group
DOI: 10.1016/j.modpat.2024.100465

Identification of an NF1 Microdeletion with Optical Genome Mapping.

Auteurs: Büki G, Bekő A, Bödör C, Urbán P, Németh K, Hadzsiev K, Fekete G, Kehrer-Sawatzki H, Bene J.
Publié dans: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms241713580

Are the Cutaneous Microbiota a Guardian of the Skin's Physical Barrier? The Intricate Relationship between Skin Microbes and Barrier Integrity.

Auteurs: Szabó K, Bolla BS, Erdei L, Balogh F, Kemény L.
Publié dans: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242115962

Characterization of the CDAA Diet-Induced Non-alcoholic Steatohepatitis Model: Sex-Specific Differences in Inflammation, Fibrosis, and Cholesterol Metabolism in Middle-Aged Mice

Auteurs: Dániel Kucsera, Viktória E. Tóth, Dorottya Gergő, Imre Vörös, Zsófia Onódi, Anikó Görbe, Péter Ferdinandy, Zoltán V. Varga
Publié dans: Frontiers in Physiology, Numéro 12, 2021, ISSN 1664-042X
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fphys.2021.609465

Physical prehabilitation improves the postoperative outcome of associating liver partition and portal vein ligation for staged hepatectomy in experimental model.

Auteurs: Daradics N, Levay K, Horvath I, Kovacs N, Mathe D, Szigeti K, Szijarto A, Fulop A.
Publié dans: Scientific reports, Numéro 20452322, 2022, ISSN 2045-2322
Éditeur: Nature Publishing Group
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Molecular Network Approach Reveals Rictor as a Central Target of Cardiac ProtectomiRs

Auteurs: András Makkos, Bence Ágg, Zoltán V. Varga, Zoltán Giricz, Mariann Gyöngyösi, Dominika Lukovic, Rainer Schulz, Monika Barteková, Anikó Görbe, Péter Ferdinandy
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Image-based and machine learning-guided multiplexed serology test for SARS-CoV-2.

Auteurs: Pietiäinen V, Polso M, Migh E, Guckelsberger C, Harmati M, Diosdi A, Turunen L, Hassinen A, Potdar S, Koponen A, Sebestyen EG, Kovacs F, Kriston A, Hollandi R, Burian K, Terhes G, Visnyovszki A, Fodor E, Lacza Z, Kantele A, Kolehmainen P, Kakkola L, Strandin T, Levanov L, Kallioniemi O, Kemeny L, Julkunen I, Vapalahti O, Buzas K, Paavolainen L, Horvath P, Hepojoki J.
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Transcriptional Analysis-Based Alterations Affecting Neuritogenesis of the Peripheral Nervous System in Psoriasis

Auteurs: Romhányi D, Szabó K, Kemény L, Sebestyén E, Groma G.
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Activated polymorphonuclear derived extracellular vesicles are potential biomarkers of periprosthetic joint infection.

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Correlations Between the Expression of Stromal Cell Activation Related Biomarkers, L-NGFR, Phospho-ERK1-2 and CXCL12, and Primary Myelofibrosis Progression.

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Three-dimensional bioprinting of functional β-islet-like constructs.

Auteurs: Parvaneh S, Kemény L, Ghaffarinia A, Yarani R, Veréb Z.
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Oscillotherapeutics – Time-targeted interventions in epilepsy and beyond

Auteurs: Yuichi Takeuchi, Antal Berényi
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Brain-derived neurotrophic factor increases cell number of neural progenitor cells derived from human induced pluripotent stem cells

Auteurs: Panetha Pansri, Phetcharat Phanthong, Nopparat Suthprasertporn, Yindee Kitiyanant, Alisa Tubsuwan, Andras Dinnyes, Julianna Kobolak, Narisorn Kitiyanant
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Hunting Out the autophagic problem in Huntington disease.

Auteurs: Pircs K, Barker RA, Jakobsson J.
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A journey to your self: The vague definition of immune self and its practical implications

Auteurs: Balázs Koncz, Gergő Mihály Balogh, Máté Manczinger
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Éditeur: National Academy of Sciences
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Stress-Related Regulation Is Abnormal in the Psoriatic Uninvolved Skin

Auteurs: Renáta Bozó, Judit Danis, Lili Borbála Flink, Dániel László Vidács, Lajos Kemény, Zsuzsanna Bata-Csörgő
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Establishment and characterization of a novel human induced pluripotent stem cell line stably expressing the iRFP720 reporter.

Auteurs: Fehér A, Schnúr A, Muenthaisong S, Bellák T, Ayaydin F, Várady G, Kemter E, Wolf E, Dinnyés A.
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Systematic review and network analysis of microRNAs involved in cardioprotection against myocardial ischemia/reperfusion injury and infarction: Involvement of redox signalling

Auteurs: András Makkos, Bence Ágg, Balázs Petrovich, Zoltán V. Varga, Anikó Görbe, Péter Ferdinandy
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SerpinB2 is involved in cellular response upon UV irradiation

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Editorial: The Role of Nuclear Molecules in the Pathogenesis of Autoimmune Disease

Auteurs: David S. Pisetsky, Reinhard Voll, Edit I. Buzas
Publié dans: Frontiers in Immunology, Numéro 12, 2021, ISSN 1664-3224
Éditeur: Frontiers Media S.A.
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Thiopurines impair the apical plasma membrane expression of CFTR in pancreatic ductal cells via RAC1 inhibition.

Auteurs: Tél B, Papp N, Varga Á, Szabó V, Görög M, Susánszki P, Crul T, Kis A, Sendstad IH, Bagyánszki M, Bódi N, Hegyi P, Maléth J, Pallagi P.
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Novel actionable ROS1::GIT2 fusion in non-Langerhans cell histiocytosis with central nervous system involvement.

Auteurs: Bedics G, Csóka M, Reiniger L, Varga E, Liptai Z, Papp G, Bekő A, Cervi C, Bödör C, Scheich B.
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Anti-PD-1 Therapy Does Not Influence Hearing Ability in the Most Sensitive Frequency Range, but Mitigates Outer Hair Cell Loss in the Basal Cochlear Region

Auteurs: Judit Szepesy, Gabriella Miklós, János Farkas, Dániel Kucsera, Zoltán Giricz, Anita Gáborján, Gábor Polony, Ágnes Szirmai, László Tamás, László Köles, Zoltán V. Varga, Tibor Zelles
Publié dans: International Journal of Molecular Sciences, Numéro 21/18, 2020, Page(s) 6701, ISSN 1422-0067
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Revealing a Phenotypical Appearance of Ibrutinib Resistance in Patients With Chronic Lymphocytic Leukaemia by Flow Cytometry.

Auteurs: Takács F, Kotmayer L, Czeti Á, Szalóki G, László T, Mikala G, Márk Á, Masszi A, Farkas P, Plander M, Weisinger J, Demeter J, Fekete S, Szerafin L, Deák BM, Szaleczky E, Sulák A, Borbényi Z, Barna G.
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Fluorescent, Prussian Blue-Based Biocompatible Nanoparticle System for Multimodal Imaging Contrast

Auteurs: László Forgách, Nikolett Hegedűs, Ildikó Horváth, Bálint Kiss, Noémi Kovács, Zoltán Varga, Géza Jakab, Tibor Kovács, Parasuraman Padmanabhan, Krisztián Szigeti, Domokos Máthé
Publié dans: Nanomaterials, Numéro 10/9, 2020, Page(s) 1732, ISSN 2079-4991
Éditeur: MDPI Multidisciplinary Digital Publishing Institute
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Simple binding of protein kinase A prior to phosphorylation allows CFTR anion channels to be opened by nucleotides

Auteurs: Csaba Mihályi, Iordan Iordanov, Beáta Töröcsik, László Csanády
Publié dans: Proceedings of the National Academy of Sciences, Numéro 117/35, 2020, Page(s) 21740-21746, ISSN 0027-8424
Éditeur: National Academy of Sciences
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PersonALL: a genetic scoring guide for personalized risk assessment in pediatric B-cell precursor acute lymphoblastic leukemia.

Auteurs: Kelemen Á, Sebestyén E, Jakab Z, Matolcsy A, Kiss C, Kovács G, Savola S, Bödör C, Alpár D.
Publié dans: British Journal of Cancer, 2023, ISSN 1532-1827
Éditeur: Nature Publishing Group
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Extracellular vesicles promote migration despite BRAF inhibitor treatment in malignant melanoma cells

Auteurs: Afrodité Németh, Gréta L. Bányai, Nikolett K. Dobos, Tamás Kós, Anikó Gaál, Zoltán Varga, Edit I. Buzás, Delaram Khamari, Magdolna Dank, István Takács, A. Marcell Szász, Tamás Garay
Publié dans: Cell Communication and Signaling, Numéro 22, 2024, ISSN 1478-811X
Éditeur: BioMed Central
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Olive Oil Improves While Trans Fatty Acids Further Aggravate the Hypomethylation of LINE-1 Retrotransposon DNA in an Environmental Carcinogen Model. Nutrients.

Auteurs: Szabo L, Molnar R, Tomesz A, Deutsch A, Darago R, Varjas T, Ritter Z, Szentpeteri JL, Andreidesz K, Mathe D, Hegedüs I, Sik A, Budan F, Kiss I.
Publié dans: Nutrients, 2022, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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Wnt Activity and Cell Proliferation Are Coupled to Extracellular Vesicle Release in Multiple Organoid Models

Auteurs: Gyöngyvér Orsolya Sándor, András Áron Soós, Péter Lörincz, Lívia Rojkó, Tünde Harkó, Levente Bogyó, Tamás Tölgyes, Attila Bursics, Edit I. Buzás, Judit Moldvay, Zoltán Wiener
Publié dans: Frontiers in Cell and Developmental Biology, Numéro 9, 2021, ISSN 2296-634X
Éditeur: Frontiers Media S.A.
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Questioning Glutamate Excitotoxicity in Acute Brain Damage: The Importance of Spreading Depolarization. Neurocrit Care.

Auteurs: Andrew RD, Farkas E, Hartings JA, Brennan KC, Herreras O, Müller M, Kirov SA, Ayata C, Ollen-Bittle N, Reiffurth C, Revah O, Robertson RM, Dawson-Scully KD, Ullah G, Dreier JP.
Publié dans: Neurocritical care, 2022, ISSN 1556-0961
Éditeur: Springer Nature
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Alzheimer’s Disease: A Molecular View of β-Amyloid Induced Morbific Events

Auteurs: Rajmohamed Mohamed Asik, Natarajan Suganthy, Mohamed Asik Aarifa, Arvind Kumar, Krisztián Szigeti, Domokos Mathe, Balázs Gulyás, Govindaraju Archunan, Parasuraman Padmanabhan
Publié dans: Biomedicines, Numéro 9/9, 2021, Page(s) 1126, ISSN 2227-9059
Éditeur: MDPI AG
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"Unraveling Transcriptome Profile, Epigenetic Dynamics, and Morphological Changes in Psoriasis-like Keratinocytes: ""Insights into Similarity with Psoriatic Lesional Epidermis"""

Auteurs: Ghaffarinia A, Póliska S, Ayaydin F, Goblos A, Parvaneh S, Manczinger M, Balogh F, Erdei L, Veréb Z, Szabó K, Bata-Csörgő Z, Kemény L.
Publié dans: Cells, 2023, ISSN 2073-4409
Éditeur: MDPI
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Altered Cellular Protein Quality Control System Modulates Cardiomyocyte Function in Volume Overload-Induced Hypertrophy.

Auteurs: Gömöri K, Herwig M, Hassoun R, Budde H, Mostafi N, Delalat S, Modi S, Begovic M, Szabados T, Pipis J, Farkas-Morvay N, Leprán I, Kovács Á, Mügge A, Ferdinandy P, Görbe A, Bencsik P, Hamdani N.
Publié dans: Atioxidants, Numéro 20763921, 2022, ISSN 2076-3921
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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Delayed Contralateral Nephrectomy Halted Post-Ischemic Renal Fibrosis Progression and Inhibited the Ischemia-Induced Fibromir Upregulation in Mice

Auteurs: Beáta Róka, Pál Tod, Tamás Kaucsár, Éva Nóra Bukosza, Imre Vörös, Zoltán V. Varga, Balázs Petrovich, Bence Ágg, Péter Ferdinandy, Gábor Szénási, Péter Hamar
Publié dans: Biomedicines, Numéro 9/7, 2021, Page(s) 815, ISSN 2227-9059
Éditeur: MDPI AG
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Degenerate but indispensable: how CFTR channel activity depends on the catalytically inactive ATP binding site?

Auteurs: László Csanády
Publié dans: The Journal of Physiology, 2021, ISSN 0022-3751
Éditeur: Blackwell Publishing Inc.
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Transient Hypoperfusion to Ischemic/Anoxic Spreading Depolarization is Related to Autoregulatory Failure in the Rat Cerebral Cortex

Auteurs: Menyhárt Á, Varga DP, M Tóth O, Makra P, Bari F, Farkas E.
Publié dans: Transient Hypoperfusion to Ischemic/Anoxic Spreading Depolarization is Related to Autoregulatory Failure in the Rat Cerebral Cortex., 2021, ISSN 1556-0961
Éditeur: Springer Nature
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Stellaria media tea protects against diabetes-induced cardiac dysfunction in rats without affecting glucose tolerance.

Auteurs: Demján V, Sója A, Kiss T, Fejes A, Gausz D, Szűcs G, Siska A, Földesi I, Tengölics R, Darula Zs, Csupor D, Pipicz M, Csont T.
Publié dans: JTCM Journal of Traditional and Complementary Medicine, 2021, ISSN 2225-4110
Éditeur: Medknow Publications and Media Pvt. Ltd
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The roles of extracellular vesicles in the immune system.

Auteurs: Buzas EI.
Publié dans: Nature Reviews Immunology, 2022, ISSN 1474-1733
Éditeur: Nature Publishing Group
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Interplay of Oxidative Stress and Necrosis-like Cell Death in Cardiac Ischemia/Reperfusion Injury: A Focus on Necroptosis.

Auteurs: Adameova A, Horvath C, Abdul-Ghani S, Varga ZV, Suleiman MS, Dhalla NS.
Publié dans: Biomedicines, 2022, ISSN 2227-9059
Éditeur: MDPI AG
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Proteotranscriptomic Discrimination of Tumor and Normal Tissues in Renal Cell Carcinoma.

Auteurs: Bartha Á, Darula Z, Munkácsy G, Klement É, Nyirády P, Győrffy B.
Publié dans: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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Volatile anaesthetics inhibit the thermosensitive nociceptor ion channel transient receptor potential melastatin 3 (TRPM3)

Auteurs: Balázs Kelemen, Erika Lisztes, Anita Vladár, Martin Hanyicska, János Almássy, Attila Oláh, Attila Gábor Szöllősi, Zsófia Pénzes, János Posta, Thomas Voets, Tamás Bíró, Balázs István Tóth
Publié dans: Biochemical Pharmacology, Numéro 174, 2020, Page(s) 113826, ISSN 0006-2952
Éditeur: Elsevier BV
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Bicarbonate Evokes Reciprocal Changes in Intracellular Cyclic di-GMP and Cyclic AMP Levels in Pseudomonas aeruginosa

Auteurs: Kasidid Ruksakiet, Balázs Stercz, Gergő Tóth, Pongsiri Jaikumpun, Ilona Gróf, Roland Tengölics, Zsolt M. Lohinai, Péter Horváth, Mária A. Deli, Martin C. Steward, Orsolya Dobay, Ákos Zsembery
Publié dans: Biology, Numéro 10/6, 2021, Page(s) 519, ISSN 2079-7737
Éditeur: MDPI
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Shared extracellular vesicle miRNA profiles of matched ductal pancreatic adenocarcinoma organoids and blood plasma samples show the power of organoid technology

Auteurs: Anikó Zeöld, Gyöngyvér Orsolya Sándor, Anna Kiss, András Áron Soós, Tamás Tölgyes, Attila Bursics, Ákos Szűcs, László Harsányi, Ágnes Kittel, András Gézsi, Edit I. Buzás, Zoltán Wiener
Publié dans: Cellular and Molecular Life Sciences, 2020, ISSN 1420-682X
Éditeur: Birkhauser Verlag
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The IV International Symposium on Fungal Stress and the XIII International Fungal Biology Conference.

Auteurs: Alder-Rangel A, Bailão AM, Herrera-Estrella A, Rangel AEA, Gácser A, Gasch AP, Campos CBL, Peters C, Camelim F, Verde F, Gadd GM, Braus G, Eisermann I, Quinn J, Latgé JP, Aguirre J, Bennett JW, Heitman J, Nosanchuk JD, Partida-Martínez LP, Bassilana M, Acheampong MA, Riquelme M, Feldbrügge M, Keller NP, Keyhani NO, Gunde-Cimerman N, Nascimento R, Arkowitz RA, Mouriño-Pérez RR, Naz SA, Avery
Publié dans: Fungal Biology, 2023, ISSN 1096-0937
Éditeur: Academic Press Inc.
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Estimating the true stability of the prehydrolytic outward-facing state in an ABC protein.

Auteurs: Simon MA, Iordanov I, Szollosi A, Csanády L.
Publié dans: eLife, 2023, ISSN 2050-084X
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Merkel K, Szöllősi D, Horváth I, Jezsó B, Baranyai Z, Szigeti K, Varga Z, Hegedüs I, Padmanabhan P, Gulyás B, Bergmann R, Máthé D.

Auteurs: Radiolabeling of Platelets with 99mTc-HYNIC-Duramycin for In Vivo Imaging Studies.
Publié dans: Internaitonal Journal of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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The Rad5 helicase and RING domains contribute to genome stability through their independent catalytic activities.

Auteurs: Toth R, Balogh D, Pinter L, Jaksa G, Szeplaki B, Graf A, Gyorfy Z, Zs Enyedi M, Kiss E, Haracska L, Unk I.
Publié dans: Journal of molecular biology, 2022, ISSN 0022-2836
Éditeur: Academic Press
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IL-1β neutralization prevents diastolic dysfunction development, but lacks hepatoprotective effect in an aged mouse model of NASH.

Auteurs: Kucsera D, Tóth VE, Sayour NV, Kovács T, Gergely TG, Ruppert M, Radovits T, Fábián A, Kovács A, Merkely B, Ferdinandy P, Varga ZV.
Publié dans: Scientific Reports, 2023, ISSN 2045-2322
Éditeur: Nature Publishing Group
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Characterization of Neurons Expressing the Novel Analgesic Drug Target Somatostatin Receptor 4 in Mouse and Human Brains

Auteurs: Angéla Kecskés, Krisztina Pohóczky, Miklós Kecskés, Zoltán V. Varga, Viktória Kormos, Éva Szőke, Nóra Henn-Mike, Máté Fehér, József Kun, Attila Gyenesei, Éva Renner, Miklós Palkovits, Péter Ferdinandy, István M. Ábrahám, Balázs Gaszner, Zsuzsanna Helyes
Publié dans: International Journal of Molecular Sciences, Numéro 21/20, 2020, Page(s) 7788, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
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Interdisciplinary Analyses of Bronze Age Communities from Western Hungary Reveal Complex Population Histories.

Auteurs: Gerber D, Szeifert B, Székely O, Egyed B, Gyuris B, Giblin JI, Horváth A, Köhler K, Kulcsár G, Kustár Á, Major I, Molnár M, Palcsu L, Szeverényi V, Fábián S, Mende BG, Bondár M, Ari E, Kiss V, Szécsényi-Nagy A.
Publié dans: Molecular Biology and Evolution, 2023, ISSN 1537-1719
Éditeur: Oxford University Press
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IDENTIFICATION OF NEGATIVE REGULATORS OF THE CUTIBACTERIUM ACNES-INDUCED INNATE IMMUNE ACTIVATION IN HUMAN EPIDERMAL KERATINOCYTES

Auteurs: Lilla Erdei
Publié dans: 2020
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Immune-inflammatory targets in chronic heart failure: inflammasomes and the endocannabinoid system

Auteurs: Zsófia Gulyás-Onódi
Publié dans: 2022
Éditeur: Semmelweis University

Értekezés címe: Az in vivo fehérjeaggregáció útvonalait befolyásoló tényezők vizsgálata Escherichia coliban

Auteurs: Györkei Ádám
Publié dans: 2022
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Discovery of small-molecule inhibitors of Rad6 function and the Rad6-Rad18 interaction

Auteurs: Sharma Gaurav
Publié dans: 2023
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A CFTR anioncsatorna extracelluláris régiójának a csatorna működésére gyakorolt hatása

Auteurs: Simon Márton András
Publié dans: 2023
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Application of Circulating Tumor DNA Analysis for the Detection of EZH2 Mutations in Follicular Lymphoma

Auteurs: Nagy Ákos
Publié dans: 2023
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BRCA1/2 patogén és ismeretlen klinikai szignifikanciájú variánsok azonosítása és vizsgálati lehetőségei

Auteurs: Gráf Alexandra
Publié dans: 2022
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The study of the membrane microdomain localization of the prion-family proteins, prion and Shadoo and their interaction with calnexin

Auteurs: Divya Teja Dondapati
Publié dans: 2022
Éditeur: University of Szeged

Hipertermia-okozta stresszválasz molekuláris mechanizmusai emlős sejtekben

Auteurs: Tiszlavicz Ádám
Publié dans: 2022
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Compensatory evolution as a driver of morphological novelties

Auteurs: Sarkadi Zsuzsa
Publié dans: 2022
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Antitumor effects of modulated electro-hyperthermia in 4T1 triple-negative breast cancer models

Auteurs: Danics Lea Orsolya
Publié dans: 2021
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Controlling cell polarity in human pancreatic organoids significantly improves the resolution of ex vivo physiological modeling

Auteurs: Varga Árpád
Publié dans: 2023
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Epigenetic consequences of in utero exposure to rosuvastatin include altered histone methylation patterns in newborn rat brains

Auteurs: Fábián-Dulka Karolina
Publié dans: 2021
Éditeur: University of Szeged

Molecular background of resistance to targeted therapies in chronic lymphocytic

Auteurs: Kotmayer Lili Eszter
Publié dans: 2023
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Potential relevance of altered cartilage oligomeric matrix protein in psoriasis

Auteurs: Renáta Bozó
Publié dans: 2020
Éditeur: University of Szeged

Discovery of small-molecule inhibitors of Uba1 and development of step-specific assays for PCNA ubiquitination

Auteurs: Paras Gaur
Publié dans: 2020
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A funkcionális metagenomika módszerének kiterjesztése kórokozó baktériumokra az antibiotikumrezisztencia vizsgálatának céljából

Auteurs: Számel Mónika
Publié dans: 2023
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CFTR deficiency causes PMCA4 dysfunction, intracellular Ca2+ elevation and promotes epithelial cell damage in alcoholic pancreatitis and hepatitis

Auteurs: Tamara Éva Madácsy
Publié dans: 2022
Éditeur: University of Szeged

Vasculitides primarily involving the skin

Auteurs: Géza Róbert Nagy
Publié dans: 2020
Éditeur: University of Szeged

RAD18-dependent Activation of FAN1 by Ub-PCNA to Rescue DNA Interstrand crosslinks along with TLS Pol η

Auteurs: Qiuzhen Li
Publié dans: 2021
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Bioanalytics, lipidomics and metabolomics application of one- and two-dimensional LC-MS techniques

Auteurs: Tímea Körmöczi
Publié dans: 2022
Éditeur: University of Szeged

The effect of Cutibacterium acnes on the barrier properties of in vitro cultured keratinocytes

Auteurs: Beáta Szilvia Bolla
Publié dans: 2020
Éditeur: University of Szeged

Szívelégtelenségben ható szerek

Auteurs: Ferdinandy Péter, Varga Zoltán In: Gyires Klára, Fürst Zsuzsanna, Ferdinandy Péter, Pintér Erika, Szilvássy Zoltán, Varró András (szerk.)
Publié dans: Farmakológia és klinikai farmakológia: egyetemi tankönyv, Numéro p. 10, 2020, Page(s) pp. 224-233
Éditeur: Medicina Könyvkiadó Zrt.

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