Design and development of advanced NAnomedicines to overcome Biological BArriers and to treat severe diseases

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Pubblicazioni

Multicellular spheroid based on a triple co-culture: A novel 3D model to mimic pancreatic tumor complexity

Autori: Gianpiero Lazzari, Valérie Nicolas, Michiya Matsusaki, Mitsuru Akashi, Patrick Couvreur, Simona Mura
Pubblicato in: Acta Biomaterialia, Numero 78, 2018, Pagina/e 296-307, ISSN 1742-7061
Editore: Elsevier BV
DOI: 10.1016/j.actbio.2018.08.008

Starch-Chitosan Polyplexes: A Versatile Carrier System for Anti-Infectives and Gene Delivery

Autori: Hanzey Yasar, Duy-Khiet Ho, Chiara De Rossi, Jennifer Herrmann, Sarah Gordon, Brigitta Loretz, Claus-Michael Lehr
Pubblicato in: Polymers, Numero 10/3, 2018, Pagina/e 252, ISSN 2073-4360
Editore: MDPI
DOI: 10.3390/polym10030252

A facile route to heterotelechelic polymer prodrug nanoparticles for imaging, drug delivery and combination therapy

Autori: Daniele Vinciguerra, Stéphanie Denis, Julie Mougin, Merel Jacobs, Yohann Guillaneuf, Simona Mura, Patrick Couvreur, Julien Nicolas
Pubblicato in: Journal of Controlled Release, Numero 286, 2018, Pagina/e 425-438, ISSN 0168-3659
Editore: Elsevier BV
DOI: 10.1016/j.jconrel.2018.08.013

Advances on the formulation of proteins using nanotechnologies

Autori: Irene Santalices, Andrea Gonella, Dolores Torres, María José Alonso
Pubblicato in: Journal of Drug Delivery Science and Technology, Numero 42, 2017, Pagina/e 155-180, ISSN 1773-2247
Editore: Editions de Sante
DOI: 10.1016/j.jddst.2017.06.018

Polysaccharide Submicrocarrier for Improved Pulmonary Delivery of Poorly Soluble Anti-infective Ciprofloxacin: Preparation, Characterization, and Influence of Size on Cellular Uptake

Autori: Duy-Khiet Ho, Ana Costa, Chiara De Rossi, Cristiane de Souza Carvalho-Wodarz, Brigitta Loretz, Claus-Michael Lehr
Pubblicato in: Molecular Pharmaceutics, Numero 15/3, 2018, Pagina/e 1081-1096, ISSN 1543-8384
Editore: American Chemical Society
DOI: 10.1021/acs.molpharmaceut.7b00967

Ultrasound-mediated drug delivery to the brain: principles, progress and prospects

Autori: Anshuman Dasgupta, Mengjiao Liu, Tarun Ojha, Gert Storm, Fabian Kiessling, Twan Lammers
Pubblicato in: Drug Discovery Today: Technologies, Numero 20, 2016, Pagina/e 41-48, ISSN 1740-6749
Editore: Elsevier BV
DOI: 10.1016/j.ddtec.2016.07.007

Telechelic polymers from reversible-deactivation radical polymerization for biomedical applications

Autori: Daniele Vinciguerra, Johanna Tran, Julien Nicolas
Pubblicato in: Chemical Communications, Numero 54/3, 2018, Pagina/e 228-240, ISSN 1359-7345
Editore: Royal Society of Chemistry
DOI: 10.1039/c7cc08544c

Evolution of Nanoparticle Protein Corona across the Blood–Brain Barrier

Autori: Alysia Cox, Patrizia Andreozzi, Roberta Dal Magro, Fabio Fiordaliso, Alessandro Corbelli, Laura Talamini, Clizia Chinello, Francesca Raimondo, Fulvio Magni, Maria Tringali, Silke Krol, Paulo Jacob Silva, Francesco Stellacci, Massimo Masserini, Francesca Re
Pubblicato in: ACS Nano, Numero 12/7, 2018, Pagina/e 7292-7300, ISSN 1936-0851
Editore: American Chemical Society
DOI: 10.1021/acsnano.8b03500

Phage-displayed peptides targeting specific tissues and organs

Autori: Josu Andrieu, Francesca Re, Laura Russo, Francesco Nicotra
Pubblicato in: Journal of Drug Targeting, 2018, Pagina/e 1-11, ISSN 1061-186X
Editore: Taylor & Francis
DOI: 10.1080/1061186x.2018.1531419

Farnesylated Glycol Chitosan as a Platform for Drug Delivery: Synthesis, Characterization, and Investigation of Mucus–Particle Interactions

Autori: Duy-Khiet Ho, Sarah Frisch, Alexander Biehl, Emmanuel Terriac, Chiara De Rossi, Konrad Schwarzkopf, Franziska Lautenschläger, Brigitta Loretz, Xabier Murgia, Claus-Michael Lehr
Pubblicato in: Biomacromolecules, Numero 19/8, 2018, Pagina/e 3489-3501, ISSN 1525-7797
Editore: American Chemical Society
DOI: 10.1021/acs.biomac.8b00795

Sonoporation enhances liposome accumulation and penetration in tumors with low EPR

Autori: Benjamin Theek, Maike Baues, Tarun Ojha, Diana Möckel, Seena Koyadan Veettil, Julia Steitz, Louis van Bloois, Gert Storm, Fabian Kiessling, Twan Lammers
Pubblicato in: Journal of Controlled Release, Numero 231, 2016, Pagina/e 77-85, ISSN 0168-3659
Editore: Elsevier BV
DOI: 10.1016/j.jconrel.2016.02.021

Tumour homing and therapeutic effect of colloidal nanoparticles depend on the number of attached antibodies

Autori: Miriam Colombo, Luisa Fiandra, Giulia Alessio, Serena Mazzucchelli, Manuela Nebuloni, Clara De Palma, Karsten Kantner, Beatriz Pelaz, Rany Rotem, Fabio Corsi, Wolfgang J. Parak, Davide Prosperi
Pubblicato in: Nature Communications, Numero 7, 2016, Pagina/e 13818, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/ncomms13818

Targeting cellular and microenvironmental multidrug resistance

Autori: Okan Tezcan, Tarun Ojha, Gert Storm, Fabian Kiessling, Twan Lammers
Pubblicato in: Expert Opinion on Drug Delivery, Numero 13/9, 2016, Pagina/e 1199-1202, ISSN 1742-5247
Editore: Ashley Publications Ltd.
DOI: 10.1080/17425247.2016.1214570

Multicellular tumor spheroids: a relevant 3D model for the in vitro preclinical investigation of polymer nanomedicines

Autori: Gianpiero Lazzari, Patrick Couvreur, Simona Mura
Pubblicato in: Polym. Chem., Numero 8/34, 2017, Pagina/e 4947-4969, ISSN 1759-9954
Editore: Royal Society of Chemistry
DOI: 10.1039/c7py00559h

Synthetic nanocarriers for the delivery of polynucleotides to the eye

Autori: Sofia M. Saraiva, Vanessa Castro-López, Covadonga Pañeda, María José Alonso
Pubblicato in: European Journal of Pharmaceutical Sciences, Numero 103, 2017, Pagina/e 5-18, ISSN 0928-0987
Editore: Elsevier BV
DOI: 10.1016/j.ejps.2017.03.001

Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors

Autori: Tarun Ojha, Vertika Pathak, Yang Shi, Wim E. Hennink, Chrit T.W. Moonen, Gert Storm, Fabian Kiessling, Twan Lammers
Pubblicato in: Advanced Drug Delivery Reviews, 2017, ISSN 0169-409X
Editore: Elsevier BV
DOI: 10.1016/j.addr.2017.07.007

Enhancing Tumor Penetration of Nanomedicines

Autori: Qingxue Sun, Tarun Ojha, Fabian Kiessling, Twan Lammers, Yang Shi
Pubblicato in: Biomacromolecules, Numero 18/5, 2017, Pagina/e 1449-1459, ISSN 1525-7797
Editore: American Chemical Society
DOI: 10.1021/acs.biomac.7b00068

Diritti di proprietà intellettuale

AMINOGLYCOSIDE DERIVATIVES AND NANO-ASSEMBLIES THEREOF, INCLUDING THOSE WITH QUORUM SENSING INHIBITORY FUNCTION

Numero candidatura/pubblicazione: EP 17179011
Data: 2017-06-30

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