Design and development of advanced NAnomedicines to overcome Biological BArriers and to treat severe diseases

Resultado final

Network Website operative.

ESRs representative nominated.

Publicaciones

Multicellular spheroid based on a triple co-culture: A novel 3D model to mimic pancreatic tumor complexity

Autores: Gianpiero Lazzari, Valérie Nicolas, Michiya Matsusaki, Mitsuru Akashi, Patrick Couvreur, Simona Mura
Publicado en: Acta Biomaterialia, Edición 78, 2018, Página(s) 296-307, ISSN 1742-7061
Editor: Elsevier BV
DOI: 10.1016/j.actbio.2018.08.008

Starch-Chitosan Polyplexes: A Versatile Carrier System for Anti-Infectives and Gene Delivery

Autores: Hanzey Yasar, Duy-Khiet Ho, Chiara De Rossi, Jennifer Herrmann, Sarah Gordon, Brigitta Loretz, Claus-Michael Lehr
Publicado en: Polymers, Edición 10/3, 2018, Página(s) 252, ISSN 2073-4360
Editor: MDPI
DOI: 10.3390/polym10030252

A facile route to heterotelechelic polymer prodrug nanoparticles for imaging, drug delivery and combination therapy

Autores: Daniele Vinciguerra, Stéphanie Denis, Julie Mougin, Merel Jacobs, Yohann Guillaneuf, Simona Mura, Patrick Couvreur, Julien Nicolas
Publicado en: Journal of Controlled Release, Edición 286, 2018, Página(s) 425-438, ISSN 0168-3659
Editor: Elsevier BV
DOI: 10.1016/j.jconrel.2018.08.013

Advances on the formulation of proteins using nanotechnologies

Autores: Irene Santalices, Andrea Gonella, Dolores Torres, María José Alonso
Publicado en: Journal of Drug Delivery Science and Technology, Edición 42, 2017, Página(s) 155-180, ISSN 1773-2247
Editor: Editions de Sante
DOI: 10.1016/j.jddst.2017.06.018

Polysaccharide Submicrocarrier for Improved Pulmonary Delivery of Poorly Soluble Anti-infective Ciprofloxacin: Preparation, Characterization, and Influence of Size on Cellular Uptake

Autores: Duy-Khiet Ho, Ana Costa, Chiara De Rossi, Cristiane de Souza Carvalho-Wodarz, Brigitta Loretz, Claus-Michael Lehr
Publicado en: Molecular Pharmaceutics, Edición 15/3, 2018, Página(s) 1081-1096, ISSN 1543-8384
Editor: American Chemical Society
DOI: 10.1021/acs.molpharmaceut.7b00967

Ultrasound-mediated drug delivery to the brain: principles, progress and prospects

Autores: Anshuman Dasgupta, Mengjiao Liu, Tarun Ojha, Gert Storm, Fabian Kiessling, Twan Lammers
Publicado en: Drug Discovery Today: Technologies, Edición 20, 2016, Página(s) 41-48, ISSN 1740-6749
Editor: Elsevier BV
DOI: 10.1016/j.ddtec.2016.07.007

Telechelic polymers from reversible-deactivation radical polymerization for biomedical applications

Autores: Daniele Vinciguerra, Johanna Tran, Julien Nicolas
Publicado en: Chemical Communications, Edición 54/3, 2018, Página(s) 228-240, ISSN 1359-7345
Editor: Royal Society of Chemistry
DOI: 10.1039/c7cc08544c

Evolution of Nanoparticle Protein Corona across the Blood–Brain Barrier

Autores: Alysia Cox, Patrizia Andreozzi, Roberta Dal Magro, Fabio Fiordaliso, Alessandro Corbelli, Laura Talamini, Clizia Chinello, Francesca Raimondo, Fulvio Magni, Maria Tringali, Silke Krol, Paulo Jacob Silva, Francesco Stellacci, Massimo Masserini, Francesca Re
Publicado en: ACS Nano, Edición 12/7, 2018, Página(s) 7292-7300, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.8b03500

Phage-displayed peptides targeting specific tissues and organs

Autores: Josu Andrieu, Francesca Re, Laura Russo, Francesco Nicotra
Publicado en: Journal of Drug Targeting, 2018, Página(s) 1-11, ISSN 1061-186X
Editor: Taylor & Francis
DOI: 10.1080/1061186x.2018.1531419

Farnesylated Glycol Chitosan as a Platform for Drug Delivery: Synthesis, Characterization, and Investigation of Mucus–Particle Interactions

Autores: Duy-Khiet Ho, Sarah Frisch, Alexander Biehl, Emmanuel Terriac, Chiara De Rossi, Konrad Schwarzkopf, Franziska Lautenschläger, Brigitta Loretz, Xabier Murgia, Claus-Michael Lehr
Publicado en: Biomacromolecules, Edición 19/8, 2018, Página(s) 3489-3501, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.8b00795

Sonoporation enhances liposome accumulation and penetration in tumors with low EPR

Autores: Benjamin Theek, Maike Baues, Tarun Ojha, Diana Möckel, Seena Koyadan Veettil, Julia Steitz, Louis van Bloois, Gert Storm, Fabian Kiessling, Twan Lammers
Publicado en: Journal of Controlled Release, Edición 231, 2016, Página(s) 77-85, ISSN 0168-3659
Editor: Elsevier BV
DOI: 10.1016/j.jconrel.2016.02.021

Tumour homing and therapeutic effect of colloidal nanoparticles depend on the number of attached antibodies

Autores: Miriam Colombo, Luisa Fiandra, Giulia Alessio, Serena Mazzucchelli, Manuela Nebuloni, Clara De Palma, Karsten Kantner, Beatriz Pelaz, Rany Rotem, Fabio Corsi, Wolfgang J. Parak, Davide Prosperi
Publicado en: Nature Communications, Edición 7, 2016, Página(s) 13818, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/ncomms13818

Targeting cellular and microenvironmental multidrug resistance

Autores: Okan Tezcan, Tarun Ojha, Gert Storm, Fabian Kiessling, Twan Lammers
Publicado en: Expert Opinion on Drug Delivery, Edición 13/9, 2016, Página(s) 1199-1202, ISSN 1742-5247
Editor: Ashley Publications Ltd.
DOI: 10.1080/17425247.2016.1214570

Multicellular tumor spheroids: a relevant 3D model for the in vitro preclinical investigation of polymer nanomedicines

Autores: Gianpiero Lazzari, Patrick Couvreur, Simona Mura
Publicado en: Polym. Chem., Edición 8/34, 2017, Página(s) 4947-4969, ISSN 1759-9954
Editor: Royal Society of Chemistry
DOI: 10.1039/c7py00559h

Synthetic nanocarriers for the delivery of polynucleotides to the eye

Autores: Sofia M. Saraiva, Vanessa Castro-López, Covadonga Pañeda, María José Alonso
Publicado en: European Journal of Pharmaceutical Sciences, Edición 103, 2017, Página(s) 5-18, ISSN 0928-0987
Editor: Elsevier BV
DOI: 10.1016/j.ejps.2017.03.001

Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors

Autores: Tarun Ojha, Vertika Pathak, Yang Shi, Wim E. Hennink, Chrit T.W. Moonen, Gert Storm, Fabian Kiessling, Twan Lammers
Publicado en: Advanced Drug Delivery Reviews, 2017, ISSN 0169-409X
Editor: Elsevier BV
DOI: 10.1016/j.addr.2017.07.007

Enhancing Tumor Penetration of Nanomedicines

Autores: Qingxue Sun, Tarun Ojha, Fabian Kiessling, Twan Lammers, Yang Shi
Publicado en: Biomacromolecules, Edición 18/5, 2017, Página(s) 1449-1459, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.7b00068

Derechos de propiedad intelectual

AMINOGLYCOSIDE DERIVATIVES AND NANO-ASSEMBLIES THEREOF, INCLUDING THOSE WITH QUORUM SENSING INHIBITORY FUNCTION

Número de solicitud/publicación: EP 17179011
Fecha: 2017-06-30
Solicitante(s): HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH

Resultado final

Publicaciones

Derechos de propiedad intelectual

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