Novel biocontrol agents for insect pests from neuroendocrinology

Informations projet

nEUROSTRESSPEP

N° de convention de subvention: 634361

DOI 10.3030/634361

Projet clôturé

Date de signature de la CE 19 Février 2015

Date de début 1 Juin 2015

Date de fin 31 Mai 2019

Financé au titre de

• SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy

Coût total € 6 995 053,75

Contribution de l’UE € 6 995 052,50

Coordonné par

UNIVERSITY OF GLASGOW
United Kingdom

Objectif

Insects are the most diverse Class of life on earth, and different insects can be essential for, or highly damaging to, agriculture, horticulture and forestry. There is a pressing need, not just for new insecticides to combat resistance, but more specific, “greener” insecticides that target deleterious insects while sparing beneficial ones. This proposal aims to identify such insecticides by turning the insects’ own hormones against them, both by designing artificial neuropeptide “mimetic” analogs as candidate compounds, and by generating transgenic insects that carry deleterious neuropeptide payloads within them, that can propagate through a population and impact on survival at times of stress.

We have assembled an international multi-actor consortium from EU member and associated member states, as well as a third country partner, with unparalleled experience in insect functional genomics, neuropeptide physiology, synthetic chemistry and synthetic biology, and in field-testing of candidates. Established links to agricultural, horticultural and forestry end-users, agencies/advisors and our SME partners ensure relevance to user need; and set out a pathway to exploitation and implementation of our results, for impact across three major economic sectors in the EU and globally.

We will deliver novel, ‘green’ neuropeptide-based insect pest biocontrol tools by:
• utilising ‘beyond the State-of-the-Art’ technologies based on two approaches: rational design of neuropeptide hormone analogues; and development of genetically-encoded neuropeptides for translational insect synthetic biology in genetic pest management.
• bridging outstanding research and technology in neuroendocrinology and genetics to end user need, to ultimately produce neuropeptide hormone analogues and genetic pest management biocontrol tools.
• validating and demonstrating these novel insect biocontrol agents in laboratory, field and forest applications, based on user need and a market-driven approach.

Champ scientifique

Not validated

• natural sciences › biological sciences › genetics
• agricultural sciences › agriculture, forestry, and fisheries › agriculture › agronomy › plant protection
• natural sciences › biological sciences › synthetic biology
• natural sciences › biological sciences › zoology › entomology
• natural sciences › chemical sciences › analytical chemistry › mass spectrometry

Programme(s)

• H2020-EU.3.2. - SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy Main Programme

Thème(s)

• SFS-03a-2014 - Native and alien pests in agriculture and forestry

Appel à propositions

H2020-SFS-2014-2015

Voir d’autres projets de cet appel

Sous appel

H2020-SFS-2014-2

Régime de financement

RIA - Research and Innovation action

Coordinateur

UNIVERSITY OF GLASGOW

• Contribution nette de l'UE: € 2 318 875,00
• Adresse: UNIVERSITY AVENUE ; G12 8QQ Glasgow ; Royaume-Uni
• Type d’activité: Higher or Secondary Education Establishments
• Coût total: € 2 318 875,00

Participants (13)

KATHOLIEKE UNIVERSITEIT LEUVEN

Belgique

• Contribution nette de l'UE: € 530 000,00
• Adresse: OUDE MARKT 13 ; 3000 Leuven
• Région: Vlaams Gewest › Prov. Vlaams-Brabant › Arr. Leuven
• Type d’activité: Higher or Secondary Education Establishments
• Coût total: € 530 000,00

UNIVERSITEIT GENT

Belgique

• Contribution nette de l'UE: € 511 625,00
• Adresse: SINT PIETERSNIEUWSTRAAT 25 ; 9000 Gent
• Région: Vlaams Gewest › Prov. Oost-Vlaanderen › Arr. Gent
• Type d’activité: Higher or Secondary Education Establishments
• Coût total: € 511 625,00

THE AGRICULTURAL RESEARCH ORGANISATION OF ISRAEL - THE VOLCANI CENTRE

Israël

• Contribution nette de l'UE: € 679 687,50
• Adresse: Derech Hamcabim 68 ; 50250 Bet Dagan
• Type d’activité: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
• Coût total: € 679 687,50

STOCKHOLMS UNIVERSITET

Suède

• Contribution nette de l'UE: € 378 406,00
• Adresse: UNIVERSITETSVAGEN 10 ; 10691 Stockholm
• Région: Östra Sverige › Stockholm › Stockholms län
• Type d’activité: Higher or Secondary Education Establishments
• Coût total: € 378 406,25

UNIVERSITAT ZU KOLN

Allemagne

• Contribution nette de l'UE: € 442 500,00
• Adresse: ALBERTUS MAGNUS PLATZ ; 50931 Koln
• Région: Nordrhein-Westfalen › Köln › Köln, Kreisfreie Stadt
• Type d’activité: Higher or Secondary Education Establishments
• Coût total: € 442 500,00

UNIVERSITY OF LEEDS

Royaume-Uni

• Contribution nette de l'UE: € 341 278,50
• Adresse: WOODHOUSE LANE ; LS2 9JT Leeds
• Région: Yorkshire and the Humber › West Yorkshire › Leeds
• Type d’activité: Higher or Secondary Education Establishments
• Coût total: € 341 278,75

SCOTTISH GOVERNMENT

Royaume-Uni

• Contribution nette de l'UE: € 62 031,00
• Adresse: St Andrews House, Regent Road ; EH1 3DG Edinburgh
• Région: Scotland › Eastern Scotland › Edinburgh
• Type d’activité: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
• Coût total: € 62 031,25

FORESTRY COMMISSION RESEARCH AGENCY

Royaume-Uni

• Contribution nette de l'UE: € 176 481,00
• Adresse: ALICE HOLT LODGE ; GU10 4LH Farnham
• Région: South East (England) › Hampshire and Isle of Wight › Central Hampshire
• Type d’activité: Research Organisations
• Coût total: € 176 481,25

UNIVERSITY OF CAPE TOWN

Afrique du Sud

• Contribution nette de l'UE: € 62 500,00
• Adresse: PRIVATE BAG X3 ; 7701 Rondebosch
• Type d’activité: Higher or Secondary Education Establishments
• Coût total: € 62 500,00

BRUKER DALTONIK GMBH

Allemagne

• Contribution nette de l'UE: € 438 375,00
• Adresse: FAHRENHEITSTRASSE 4 ; 28359 BREMEN
• Région: Bremen › Bremen › Bremen, Kreisfreie Stadt
• Type d’activité: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Coût total: € 438 375,00

THE PIRBRIGHT INSTITUTE LBG

Royaume-Uni

• Contribution nette de l'UE: € 719 860,00
• Adresse: ASH ROAD PIRBRIGHT ; GU24 0NF Woking
• Région: South East (England) › Surrey, East and West Sussex › West Surrey
• Type d’activité: Research Organisations
• Coût total: € 719 860,00

Oxitec Limited

Royaume-Uni

• Contribution nette de l'UE: € 245 933,50
• Adresse: Miton park 71 ; OX14 4RX Oxford
• PME L’entreprise s’est définie comme une PME (petite et moyenne entreprise) au moment de la signature de la convention de subvention. Oui:
  Région
  South East (England) › Berkshire, Buckinghamshire and Oxfordshire › Oxfordshire
• Région: South East (England) › Berkshire, Buckinghamshire and Oxfordshire › Oxfordshire
• Type d’activité: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Coût total: € 245 933,75

KNOWLEDGE TRANSFER NETWORK LIMITED

Royaume-Uni

• Contribution nette de l'UE: € 87 500,00
• Adresse: 52 UPPER STREET SUITE 218 BUSINESS DESIGN CENTRE ISLINGTON ; N1 0QH London
• PME L’entreprise s’est définie comme une PME (petite et moyenne entreprise) au moment de la signature de la convention de subvention. Oui:
  Région
  London › Inner London — East › Haringey and Islington
• Région: London › Inner London — East › Haringey and Islington
• Type d’activité: Other
• Coût total: € 87 500,00