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Zawartość zarchiwizowana w dniu 2024-06-18

Direct Alkylation of Saturated Cyclic Amines via catalytic C-H Functionalization

Cel

"Direct conversion of C-H into C-C bonds is arguably indispensable in modern organic chemistry, as it allows for obtaining target compounds which are otherwise only accessible via lengthy procedures involving multi-step synthesis. Catalytic C-H functionalization is the most attractive approach to achieve this goal, as it does not require stoichiometric amounts of activating reagent. This research proposal aims to develop direct transition metal-catalyzed functionalizations of C(sp3)–H bonds in saturated nitrogen-based heterocycles, with a particular focus on compatibility with a very broad range of functional groups, regioselectivity and stereoselectivity. Towards this goal, insertion reactions with substituted alkenes featuring a variety of functional groups will be explored. The development of such a technology offers an important contribution to novel, improved and more sustainable synthetic pathways and is expected to be highly warranted for drug discovery purposes."

Zaproszenie do składania wniosków

FP7-PEOPLE-2012-IIF
Zobacz inne projekty w ramach tego zaproszenia

Koordynator

UNIVERSITEIT ANTWERPEN
Wkład UE
€ 169 800,00
Adres
PRINSSTRAAT 13
2000 Antwerpen
Belgia

Zobacz na mapie

Region
Vlaams Gewest Prov. Antwerpen Arr. Antwerpen
Rodzaj działalności
Higher or Secondary Education Establishments
Kontakt administracyjny
Anne Adams (Mrs.)
Linki
Koszt całkowity
Brak danych