Obiettivo
Vaccines so far have been developed mostly by following an empiric approach. To prevent and possibly cure unresolved and emerging infectious diseases we need to fully exploit the potential of the human immune system. Progress in science and technology makes it possible to achieve what was previously deemed impossible. The scope of this project is to produce knowledge necessary to develop novel and powerful immunization technologies for the next generation of human vaccines. This goal requires a multidisciplinary approach in which diverse but complementary scientific disciplines and technologies converge. Therefore some of the most competitive European research groups from public institutions and biotechs have agreed to join forces in ADITEC, together with top US groups on systems biology and adjuvants to support this enterprise.
A systems biology approach will be used to study licensed and experimental vaccines in patient characterization studies and in clinical trials, to investigate the effect of adjuvants, vectors, formulations, delivery devices, routes of immunization, homologous and heterologous prime–boost schedules, as well as the impact of host factors such as age, gender, genetics and pathologies. Animal models will be used to complement human studies, and to select novel immunization technologies to be advanced to the clinic.
To address these issues in a coordinated manner, ADITEC is organised on a matrix structure in which research themes and experimental approaches feed into each other. Training curricula will be created to impact on the formation of the next generation of EU researchers in the field. ADITEC scientists and institutions are part of the “Sclavo Vaccines Association” (SVA), which is dedicated to vaccines and vaccine research. SVA, acting as the coordinating institution, guarantees the long-term commitment and sustainability of this initiative, beyond the duration of ADITEC itself.
Campo scientifico
- natural sciencesbiological sciencesgenetics
- medical and health sciencesbasic medicineimmunologyimmunisation
- medical and health scienceshealth sciencesinfectious diseases
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccines
- medical and health sciencesbasic medicinepathology
Invito a presentare proposte
FP7-HEALTH-2011-single-stage
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Meccanismo di finanziamento
CP-IP - Large-scale integrating projectCoordinatore
53100 Siena
Italia
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Partecipanti (51)
2300 Kobenhavn S
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SW17 0RE London
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80539 Munchen
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75724 Paris
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OX1 2JD Oxford
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53100 Siena
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1211 Geneve
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53100 SIENA
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69007 LYON
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1030 Vienna
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405 30 Goeteborg
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2333 ZA Leiden
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30322 Atlanta
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8219 PK LELYSTAD
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1010 Wien
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98102 Seattle Wa
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3584 CS Utrecht
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20089 Rozzano
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6500 Bellinzona
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00161 Roma
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WC2R 2LS London
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1211 Geneve
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75015 PARIS 15
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75794 Paris
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3015 GD Rotterdam
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53100 Siena
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75001 PARIS
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101 Reykjavik
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00128 Roma
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9 DUBLIN
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0349 OSLO
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3063 ITTIGEN
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421 74 VASTRA FROLUNDA
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3584 CH UTRECHT
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53035 Monteriggioni
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8952 SCHLIEREN
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111 45 STOCKHOLM
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5627 VV EINDHOVEN
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53100 Siena
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SW1W 9SZ London
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98109 5240 SEATTLE WA
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SW7 2AZ LONDON
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GU2 7XH Guildford
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1030 Wien
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1010 WIEN
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6020 Innsbruck
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11145 Stockholm
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53100 Siena Si
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LS2 7UE Leeds
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1030 WIEN
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1330 Rixensart
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