Heat shock protein 60 as a novel therapeutic target for diabetes and rheumatoid arthritis (HSPFORTHERAPY)

Project Information

HSPFORTHERAPY

Grant agreement ID: QLG1-CT-2002-01287

Project closed

Start date 1 September 2002

End date 30 June 2005

Funded under

• Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Total cost € 1 409 275,00

EU contribution € 1 299 892,00

Coordinated by

UTRECHT UNIVERSITY
Netherlands

Objective

Heat shock proteins are antigens of immune responses in autoimmunity. In experimental models they suppress inflammation and in clinical trials in diabetes and arthritis hsp60 has a proven therapeutic potential. We propose to analyse the underlying mechanisms by monitoring immunity to hsp60 in the models, in patients and during hsp60 peptide trials, with respect to both the adaptive and the innate part of the immune system.

Fields of science

• medical and health sciences › clinical medicine › rheumatology
• natural sciences › biological sciences › biochemistry › biomolecules › proteins
• medical and health sciences › clinical medicine › endocrinology › diabetes
• medical and health sciences › basic medicine › immunology

Programme(s)

• FP5-LIFE QUALITY - Specific Programme for research, technological development and demonstration on "Quality of life and management of living resources", 1998-2002

Topic(s)

• 1.1.1.-7. - Chronic and degenerative diseases, cancer, diabetes, cardivascular diseases and rare diseases

Call for proposal

Data not available

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

UTRECHT UNIVERSITY

• EU contribution: No data
• Address: Yalelaan 1 ; 3584 CL UTRECHT ; Netherlands
• Total cost: No data

Participants (5)

DEUTSCHE DIABETES FORSCHUNGSGESELLSCHAFT E.V.

Germany

• EU contribution: No data
• Address: Auf'm Hennekekamp 65 ; 40225 DUESSELDORF
• Total cost: No data

PEPTOR LTD

Israel

• EU contribution: No data
• Address: Kyriat Weizmann, Building 16 ; 76326 REHOVOT
• Total cost: No data

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE

United Kingdom

• EU contribution: No data
• Address: Hills Road Addenbrooke's NHS Trust 5 ; CB2 2QQ Cambridge
• Total cost: No data

UNIVERSITY MEDICAL CENTRE UTRECHT

Netherlands

• EU contribution: No data
• Address: Lundlaan 6 ; 3584EA UTRECHT
• Total cost: No data

WEIZMANN INSTITUTE OF SCIENCE

Israel

• EU contribution: No data
• Address: Herzel Street 2 ; 76100 REHOVOT
• Total cost: No data