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GUT VIrus BRain Axis Technology In OrgaNoid Science

CORDIS bietet Links zu öffentlichen Ergebnissen und Veröffentlichungen von HORIZONT-Projekten.

Links zu Ergebnissen und Veröffentlichungen von RP7-Projekten sowie Links zu einigen Typen spezifischer Ergebnisse wie Datensätzen und Software werden dynamisch von OpenAIRE abgerufen.

Leistungen

Protocol for establishing the gut-epithelial model in STACKS [M6]. A standard protocol for the transfer of gut epithelial monolayer model from Transwell to STACKS will be provided. [R] [PU]

Protocol for establishing the gutepithelial model in STACKS M6 A standard protocol for the transfer of gut epithelial monolayer model from Transwell to STACKS will be provided R PU

Report on diffusion properties through the Biosilk matrix [M12]. Diffusion properties of fluorochromes in the Biosilk network with and without cells will be reported. [R] [PU]

Report on diffusion properties through the Biosilk matrix M12 Diffusion properties of fluorochromes in the Biosilk network with and without cells will be reported R PU

Definition of standard values for specific immune response parameters in the gut epithelial-immune cell co-culture model [M24]. A report on the measured standard values for immune markers will be available. [R] [PU]
Manuscript on the effect of fibroblasts on gut epithelial differentiation [M24]. The role of fibroblasts within the Biosilk network to effect gut differentiation in vitro will be elucidated. [R] [PU]
Protocol for cytotoxicity assay in gut mucosa model [M30] [Report on the best method for cytotoxicity assessment] [R] [PU]
Protocol for iPSC-derived BBB model [M24] [A standard protocol for establishing a BBB model will be provided]. [R] [PU]
Manuscript on the method to co-culture gut-epithelial model with immune cells [M24]. [R] [PU]
Report on the properties of the Biosilk network [M24]. The complete properties of the Biosilk network such as tensile and cell motility will be characterised. [R] [PU]
Characterisation panel for iPSC-derived BBB model. [M24] [Report on standard range of parameters for BBB model] [R] [PU]
Report on the properties of the Biosilk nanomembrane [M24]. The complete properties of the Biosilk nanomembrane such as porosity and mass transport will be characterised. [R] [PU]
"Protocol for patterning ""crypt-villi"" features on Biosilk [M9]. A standard protocol for embossing or casting ""crypt-villi"" structures will be delivered. [R] [PU]"

Protocol for patterning cryptvilli features on Biosilk M9 A standard protocol for embossing or casting cryptvilli structures will be delivered R PU

Veröffentlichungen

A quantitative meta-analysis: Is organ on a chip cell cultures better than static cell cultures?

Autoren: Martin Dufva
Veröffentlicht in: Scientific Reports, 2023, ISSN 2045-2322
Herausgeber: Nature Publishing Group
DOI: 10.21203/rs.3.rs-2208798/v1

Non-Polio Enterovirus C Replicate in Both Airway and Intestine Organotypic Cultures

Autoren: Giulia Moreni, Hetty van Eijk, Gerrit Koen, Nina Johannesson, Carlemi Calitz, Kimberley Benschop, Jeroen Cremer, Dasja Pajkrt, Adithya Sridhar, Katja Wolthers
Veröffentlicht in: Viruses, Ausgabe 15, 2025, Seite(n) 1823, ISSN 1999-4915
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v15091823

Understanding neurotropic enteric viruses: routes of infection and mechanisms of attenuation

Autoren: Valeria Lulla, Adithya Sridhar
Veröffentlicht in: Cellular and Molecular Life Sciences, Ausgabe 81, 2024, ISSN 1420-682X
Herausgeber: Birkhauser Verlag
DOI: 10.1007/s00018-024-05450-6

A quantitative meta-analysis comparing cell models in perfused organ on a chip with static cell cultures

Autoren: Martin Dufva
Veröffentlicht in: Scientific Reports, Ausgabe 13, 2023, ISSN 2045-2322
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41598-023-35043-5

Current and Future Antiviral Strategies to Tackle Gastrointestinal Viral Infections

Autoren: Nanci Santos-Ferreira, Jana Van Dycke, Johan Neyts, Joana Rocha-Pereira
Veröffentlicht in: Microorganisms, Ausgabe 9, 2024, Seite(n) 1599, ISSN 2076-2607
Herausgeber: Microorganisms
DOI: 10.3390/microorganisms9081599

Amino acid variation at VP1-145 of enterovirus A71 determines the viral infectivity and receptor usage in a primary human intestinal model

Autoren: Ikrame Aknouch, Inés García-Rodríguez, Francesca Paola Giugliano, Carlemi Calitz, Gerrit Koen, Hetty van Eijk, Nina Johannessson, Sjoerd Rebers, Lieke Brouwer, Vanesa Muncan, Koert J. Stittelaar, Dasja Pajkrt, Katja C. Wolthers, Adithya Sridhar
Veröffentlicht in: Frontiers in Microbiology, Ausgabe 14, 2023, ISSN 1664-302X
Herausgeber: Frontiers Media
DOI: 10.3389/fmicb.2023.1045587

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