Streamlined Geriatric and Oncological evaluation based on IC Technology for holistic patient-oriented healthcare management for older multimorbid patients

Deliverables

These charters will describe memberships roles and responsibilities of the Trial Steering Committee oversight body for the trials on behalf of the sponsor and the Trial Management Team setup to carry out daytoday management of the trials

First study subject approvals package for TWOBE

This package will include the final version of the TWOBE trial protocol, the registration number of the clinical trial (clinicaltrials.gov) and the regulatory and/or ethics approvals.

Dataset of symptoms and PROMs for specific cancer types and gender

This deliverable aims to describe 5 symptoms 5 indicators of destabilized comorbidities and 3 indicators of functional decline which take into account specific cancer types and gender differences

Clinical trial methodology

This is a summary of the clinical trial methodology that will be inlcuded in the final version of the FRONE and TWOBE trial protocol

Coordination strategy for stakeholders' engagement

This Deliverable will detail GerOnTe strategy for all stakeholders involvement related to the creation of HolisTM GV This document will include the specific goals of the partners strategy and a timeline for all cocreation sessions ie Focus Groups and smallscale pilots in France Belgium and the Netherlands The D61 will also include an action plan for all Focus Groups including the needs in terms of required time logistics specific goals of each organised Focus Group human resources and general methodology to moderate the Focus Group to engage discussion Each local partner will contribute to the deliverable with countryspecific consideration such as ethical committees to be considered The recruitment process ie recruitment channels participant numbers for the cocreation session will also be detailed in this deliverable

Practical guidebook and tools for Focus Groups in WP1-5

This deliverable will detail the common methods and tools for organizing the co-creation sessions about Holis(TM) creation in the framework of the technical WPs 1 to 5. This deliverable will be a guidebook to be addressed to the host of the Focus Group explaining moderation of the discussion, collection of the participants’ feedback and how to report the users’ feedback for the consortium for further implementation in the GerOnTe system. This document will also include the necessary support tools for the participants (information documents, informed consent, presentations). It will specify the following aspects for the Focus Groups: project presentation, Focus Group objective presentation, guideline for leading Focus Group discussions as well as recommendations for collection users’ feedback during the Focus Groups.The guidebook will be updated at M9, M24 and M48

Care pathways in the 3 trial countries

This deliverable is intended to describe the current care pathways for older multimorbid patients within the three pilot countries in terms of professionals involved, care settings and activities. The description of the care pathways in the 3 trials countries during GerOnTe implementation will be updated at M58.

Literature review on the cost-effectiveness of healthcare services for older multimorbid patients

This report will describe what are the existing methods and models suitable to capture the main potential of GerOnTe and will identify the distinctive feature of service and delivery interventions that pose challenges to the economic analysis of GerOnTe model

Dataset of self-management recommendations for patient-driven improvement of independent living

This deliverable aims to describe 15 common symptoms and related selfmanagement recommendations that patients can access during their treatment trajectory

First study subject approvals package for FRONE

This package will include the final version of the FRONE trial protocol, the registration number of the clinical trial (clinicaltrials.gov) and the regulatory and/or ethics approvals.

Project personalized visual identity designed

An original design will be created with the help of a professional designer for the visual identity and graphical charter of the project The graphical charter will be used for all project communication activities

Dedicated Website, Twitter and LinkedIn accounts live

LinedIn and Twitter accounts dedicated to the project will be opened and managed continously for wide communication of project and other related information A dedicated project website will be created and live at M3 regularly fed with updates throughout the life of the project

Brochure

During the early months of GerOnTe for promotion and communication purposes a professionally designed brochure will be produced It will serve as an advertisement tool electronic version for download on the project website and a printed version describing the main objectives of the project summarized with an overview of the consortium partners as well as a brief outline and description GerOnTes commitment and aims It will essentially provide a quick on the spot core information about GerOnTe

Core dataset of health professionals, multimorbidity and intrinsic capacity for the GerOnTe model

This deliverable aims to list 1 the five most common patient profiles with for each of them at least 13 health professionals listed 5 HPC core members and 8 additional professionals depending on the comorbidities geriatric needs and hospital resources 2 at least five medical data components that need to be available in the common medical file for all patients and 3 a core dataset of at least 4 frailty components 3 intrinsic capacity components and 3 patient preferences that need to be included in each CGA

Protocol for intrinsic capacity evaluation

This deviverable aims to present a protocol for CGA adapted from geriatric medicine to incorporate factors identified in D1.3 that are relevant for intrinsic capacity and self-management.

Publications

GERONTE project: Participatory Rapid Appraisal for the co-design of a technology-supported improved care pathway for older cancer patients with multimorbidity

Author(s): Bridget O Sullivan; Professor Pierre Soubeyran; Dr. Shane O Hanlon; Marianne Gros; Eleonore Lehn; Professor Regina Connolly; Dr. Trudy Corrigan; Dr Lucia Ferrara; Vittoria Ardito; Professor Anthony Staines; Dr. Ciara White; Dr. Paul Davis
Published in: 2022
Publisher: Zenodo
DOI: 10.5281/zenodo.7070788

Development of an Implementation Framework to evaluate individual and collective components of Complex Intervention using Technology (CL-uT): An Action Research study as part of a multisite Randomised Controlled Trial.

Author(s): Bridget O’ Sullivan, Professor Anthony Staines, Dr. Paul Davis, Professor Regina Connolly, Dr. Trudy Corrigan, Dr. Ciara White, Dr. Shane O’ Hanlon.
Published in: 2022
Publisher: Zenodo
DOI: 10.5281/zenodo.7071443

GERONTE project: Participatory Rapid Appraisal and Focus Groups method to co-design a technology-supported care pathway for older cancer patients with multimorbidity

Author(s): Professor Anthony Staines; Dr. Paul Davis; Professor Regina Connolly; Dr. Trudy Corrigan; Dr. Ciara White; Bridget O Sullivan4; Dr. Shane O Hanlon; Eleonore Lehn; Marianne Gros; Dr. Marije Hamaker; Dr. Petronella (Nelleke) Segher; Professor Pierre Soubeyran
Published in: 2022
Publisher: Zenodo
DOI: 10.5281/zenodo.7072961

GERONTE Project: Development of a Framework to support implementation of Complex InterventiOns using Technology (CIo-uT): An Action Research study as part of multisite Randomised Controlled Trial

Author(s): Bridget O Sullivan; Professor Anthony Staines; Dr. Paul Davis; Professor Regina Connolly; Dr. Trudy Corrigan; Dr. Ciara White; Dr. Shane O Hanlon
Published in: 2022
Publisher: Zenodo
DOI: 10.5281/zenodo.7073047

Development of a framework for a business plan to support the implementation of complex interventions (using technology) in case management across diverse healthcare settings

Author(s): Dr. Paul Davis, Professor Regina Connolly, Professor Anthony Staines, Dr. Trudy Corrigan, Dr. Ciara White, Dr. Shane O’ Hanlon, Bridget O’ Sullivan.
Published in: 2022
Publisher: Zenodo
DOI: 10.5281/zenodo.7071362

Intrinsic capacity and resilience: Taking frailty to the next level

Author(s): Hamaker, Marije; Gijzel, Sanne; Rostoft, Siri; van den Bos, Frederiek
Published in: Journal of Geriatric Oncology, 2023, ISSN 1879-4068
Publisher: Elsevier BV
DOI: 10.1016/j.jgo.2022.101421

Achieving harmony in oncological geriatric assessment – Should we agree on a best set of tools? CON discussion

Author(s): Siri Rostoft, Nelleke Seghers, Marije Hamaker
Published in: Journal of Geriatric Oncology, 2023, ISSN 1879-4068
Publisher: Elsevier BV
DOI: 10.1016/j.jgo.2023.101473

Geriatric assessment in the management of older patients with cancer – A systematic review (update)

Author(s): Hamaker, Marije; Lund, Cecilia; te Molder, Marthe; Soubeyran, Pierre; Wildiers, Hans; van Huis, Lieke; Rostoft, Siri
Published in: Journal of Geriatric Oncology, 2022, Page(s) P761-777, ISSN 1879-4068
Publisher: Elsevier BV
DOI: 10.1016/j.jgo.2022.04.008

Development and testing of the Outcome Prioritization Tool adjusted to older patients with cancer: A pilot study

Author(s): Petronella A.L. Seghersa, Marije E. Hamakera, Hanneke van der Wal-Huismanb, Mariken E. Stegmannc, Johanneke E.A. Portieljed, Pauline de Graeffe, Suzanne Festen
Published in: Journal of Geriatric Oncology, 2023, ISSN 1879-4068
Publisher: Elsevier BV
DOI: 10.1016/j.jgo.2023.101590

Patient Preferences for Treatment Outcomes in Oncology with a Focus on the Older Patient—A Systematic Review

Author(s): Petronella A. L. (Nelleke) Seghers, Anke Wiersm, Suzanne Festen, Mariken E. Stegmann, Pierre Soubeyran, Siri Rostoft, Shane O’Hanlon, Johanneke E. A. Portielje, Marije E. Hamaker
Published in: Cancers, 2022, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14051147

Study protocol for two stepped-wedge interventional trials evaluating the effects of holistic information technology-based patient-oriented management in older multimorbid patients with cancer: The GERONTE trials

Author(s): Marije Hamaker; Hans Wildiers; Vittoria Ardito; Julie Arsandaux; Aurore Barthod-Malat; Paul Davis; Lien Degol; Lucia Ferrara; Cindy Kenis; Marion Kret; Caroline Lalet; SImone Mathoulin Pelissier; Shane O'Hanlon; Siri Rostoft; Nelleke Seghers; Florence Saillour-Glénisson; Anthony Staines; Christine Schwimmer; Vincent Thevenet; Cedrick Wallet; Pierre Soubeyran
Published in: Journal of Geriatric Oncology, 2024, ISSN 1879-4068
Publisher: Elsevier BV
DOI: 10.1016/j.jgo.2024.101761

Achieving harmony in oncological geriatric assessment – Should we agree on a best set of tools? PRO discussion

Author(s): Soubeyran, Pierre-Louis; Bellera, Carine; Paillaud, Elena
Published in: Journal of Geriatric Oncology, 2023, ISSN 1879-4068
Publisher: Elsevier BV
DOI: 10.1016/j.jgo.2023.101482

Challenges of caring for older patients with multimorbidity including cancer

Author(s): P.A.L. (Nelleke) Seghersa, Siri Rostoftb,c, Shane O’Hanlond,e, Bridget O’Sullivanf, Johanneke E.A. Portieljeg, Hans Wildiersh, Pierre Soubeyrani, Marije E. Hamaker
Published in: Journal of Geriatric Oncology, 2023, ISSN 1879-4068
Publisher: Elsevier BV
DOI: 10.1016/j.jgo.2023.101588

How to incorporate chronic health conditions in oncologic decision-making and care for older patients with cancer? A survey among healthcare professionals Research Paper Open access

Author(s): P. A. L. (Nelleke) Seghers, Siri Rostoft, Shane O’Hanlon, Anita O’Donovan, Karlijn Schulkes, Isacco Montroni, Johanneke E. A. Portielje, Hans Wildiers, Pierre Soubeyran, Marije E. Hamaker
Published in: European Geriatric Medicine, 2024, ISSN 1878-7649
Publisher: Elsevier Masson
DOI: 10.1007/s41999-023-00919-2

What Defines Quality of Life for Older Patients Diagnosed with Cancer? A Qualitative Study

Author(s): Petronella A. L. (Nelleke) Seghers, Jolina A. Kregting, Lieke H. van Huis-Tanja, Pierre Soubeyran, Shane O'Hanlon, Siri Rostoft, Marije E. Hamaker, Johanneke E. A. Portielje
Published in: cancers, 2022, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14051123

Geriatric assessment for older people with cancer: policy recommendations

Author(s): Seghers, Nelleke; alibhai, Shabbir; Battisti, Nicolo; Ravindran, Kanesvaran; Extermann, Martine; O'Donovan, Anita; Pilleron, Sophie; Mislang, Anna Rachelle; Musolino, Najia; Cheung, KL; Staines, Anthony; Girvalaki, Charis; Soubeyran, Pierre; Portielje, Johanneke; Rostoft, Siri; Hamaker, Marije; Trepel, Dominic; O'Hanlon, Shane
Published in: Global Health Research and Policy, 2023, ISSN 2397-0642
Publisher: Springer Nature Group
DOI: 10.1186/s41256-023-00323-0

Preferred and actual involvement of caregivers in oncologic treatment decision-making: A systematic review

Author(s): Tielemans, Laura; Heugten, Kirsten; Hamaker, Marije; van Walree, Inez
Published in: Journal of Geriatric Oncology, 2023, ISSN 1879-4068
Publisher: Elsevier BV
DOI: 10.1016/j.jgo.2023.101525

A meta-analysis on the role older adults with cancer favour in treatment decision making

Author(s): de Waal, Maike; Seghers, Nelleke; Welsing, P; Emmelot-Vink, Marielle; Hamaker, Marije
Published in: Journal of Geriatric Oncology, 2023, ISSN 1879-4068
Publisher: Elsevier BV
DOI: 10.5281/zenodo.7308287

Self-reported electronic symptom monitoring in older patients with multimorbidity treated for cancer: Development of a core dataset based on expert consensus, literature review, and quality of life questionnaires

Author(s): P.A.L. Nelleke Seghersa, Marije E. Hamakera, Shane O’Hanlonb,c, Johanneke E.A. Portieljed, Hans Wildierse, Pierre Soubeyranf, Annemarie Coolbrandtg,h, Siri Rostoft
Published in: Journal of Geriatric Oncology, 2024, ISSN 1879-4068
Publisher: Elsevier BV
DOI: 10.1016/j.jgo.2023.101643

A care pathway for older patients with multimorbidity including cancer - Design of the GERONTE pathway

Author(s): P.A.L. Nelleke Seghersa,*, Siri Rostoftb,c, Shane O'Hanlond,e, Lien Degolf,g, Cindy Kenisf,g, Hans Wildiersh, Pierre Soubeyrani, Marije E. Hamaker
Published in: Journal of Geriatric Oncology, 2023, ISSN 1879-4068
Publisher: Elsevier BV
DOI: 10.1016/j.jgo.2023.101654

Information needs of older patients newly diagnosed with cancer

Author(s): Hamaker Marije Emilie, van Walree Inez Charlotte, Seghers Petronella A.L.(Nelleke), van den Bos Frederiek, Soubeyran Pierre, O'Hanlon Shane, Rostoft, Siri
Published in: Journal of Geriatric Oncology, 2021, ISSN 1879-4076
Publisher: Elsevier
DOI: 10.1016/j.jgo.2021.09.011

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Deliverables

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