Risultati finali
Full-cohort individual MEG brain dynamics measures at the disposal of other WPs, harmonized with Task 3.3 M36 deliverable
Fullcohort individual MEG brain dynamics measures at the disposal of other WPs harmonized with Task 33 M36 deliverable
Integrated, open source terminology versioning and management tool CTS2 compliant application shared with project partnersStakeholder Conference: Specific issues of neurodegenerative diseases: The patients’ perspective
Stakeholder Conference Specific issues of neurodegenerative diseases The patients perspective
Framework for multi-modal integrated annotations established and in useFramework for multimodal integrated annotations established and in use
Group level SEEG brain dynamics measures and analysis pipeline for SEEGShort list of candidate mechanisms to be used in personalized simulations. The short list will be explained and motivated in a dedicated Webinar that will be made publicly available
Short list of candidate mechanisms to be used in personalized simulations The short list will be explained and motivated in a dedicated Webinar that will be made publicly available
TVB human models will be made available. We will identify the biophysical terms in the TVB models that are altered in NDD as compared to healthy individuals, and in relation to cognitive statusValidated and benchmarked data fitting workflow will be provided as a software for brain model personalization
Digital atlas that maps signaling pathways on corresponding brain regions for different neurodegenerative states in humans
Initial version of full-scope containerized pipeline developed
Initial version of fullscope containerized pipeline developed
Stakeholder conference on GDPR-impactStakeholder conference on GDPRimpact
Evaluation and optimization of pipeline for practical use concludedWorkshop with policy-makers
Workshop with policymakers
Optimization and evaluation of pipeline for practical use concludedPresentations at conferences and exhibitions, organization of yearly stakeholder event, participation in science outreach events
The consortium will create a sup-page on the public project website. The VirtualBrainCloud activities will be updated permanently. In addition short summaries will be published annually (M12, M24, M36, M48) and be included in the contarctual periodic reports. The final summary will be published and submitted in project month 48.
CTS2 standard compliant interface will be released to project partnersFull-cohort MEG time series in BIDS share and analysis pipeline ready
Fullcohort MEG time series in BIDS share and analysis pipeline ready
Seamless integration of electrophysiological data workflows with TVB modelingMost appropriate RS-processing pipelines for TVB modelling finished
Most appropriate RSprocessing pipelines for TVB modelling finished
Workflows established that link progression models and TVBEstablishment of contact with relevant external stakeholders
Gateway to PRACE documentation and guidelines
Report on VBC operation report and published services on EOSC/EGI Marketplace
Report on VBC operation report and published services on EOSCEGI Marketplace
Publication of a study on deconfounding for inferenceComplete, updated semantic framework for neurodegeneration research documented
Evaluation of cross-modal atlas-based compression for machine-learning
Evaluation of crossmodal atlasbased compression for machinelearning
Deliverable: Publication of a causality study based on an instrumental variables approachReport on cloud implementation strategy applying “trusted cloud” principles
Paper manuscript describing the initial characterization of the studies, the equivalence of their variables and the summary statistics (mean, standard deviation etc.) submitted to relevant journal
Final analysis of relevant legal, ethical and regulatory framework, 2nd iteration, including a report on best practices and industry standards
Data catalogue with harmonized annotations at project
Text mining workflow to use ontologies and terminologies in OLS for information extraction of causeandeffect statements The demonstration will be delivered as a Webinar
Final VBC platform is fully integrated and validated and full documentation of its functionalitiesA functionally integrated version of VBC is evaluated for therapeutical targets
Short title: Semantically enhanced multi-viewer that embeds a newly developed TVB 3D viewer
Full title A semantically enhanced multiviewer that embeds a newly developed TVB 3D viewer that allows for integration of personalized 3D coordinates with knowledge about pathways and mechanisms in situ The deliverable for this task is a joint highranking journal publication of the teams building this environment
Validated Use Case of a brain simulation platform for NDD, usable by scientists and clinicians, for subsequent refined clinical studies towards development of therapeutic targets associated with basic physiological mechanisms"Webinar with demonstration of personalized simulation (""case studies"") using the integrated model in TVB"
Webinar with demonstration of personalized simulation (“case studies”) using the integrated model in TVB
Short title: Health & lifestyle recommendation system implementedFull title: Health & lifestyle recommendation system implemented in the VirtualBrainCloud patient interface App; compiled and edited recommendation manual including early and late factors with impact on neurodegenerative diseases; dissemination to clinics and patient groups
Pubblicazioni
Autori:
Colin Birkenbihl; Colin Birkenbihl; Mohammad Asif Emon; Mohammad Asif Emon; Henri A. Vrooman; Sarah Westwood; Simon Lovestone; Martin Hofmann-Apitius; Martin Hofmann-Apitius; Holger Fröhlich; Holger Fröhlich
Pubblicato in:
The E P M A Journal, Numero 1, 2020, ISSN 1878-5077
Editore:
BioMed Central
DOI:
10.1007/s13167-020-00216-z
Autori:
Justin W.M. Domhof; Simon B. Eickhoff; Oleksandr V. Popovych
Pubblicato in:
NeuroImage 257, 119321 (2022). doi:10.1016/j.neuroimage.2022.119321, Numero 13, 2022, ISSN 1053-8119
Editore:
Academic Press
DOI:
10.1016/j.neuroimage.2022.119321
Autori:
Clément Mantoux; Baptiste Couvy-Duchesne; Federica Cacciamani; Stéphane Epelbaum; Stanley Durrleman; Stéphanie Allassonnière
Pubblicato in:
Entropy, Numero 2, 2021, ISSN 1099-4300
Editore:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/e23040490
Autori:
Justin W. M. Domhof; Kyesam Jung; Simon B. Eickhoff; Oleksandr V. Popovych
Pubblicato in:
Network neuroscience, Numero 5(3), 2021, Pagina/e 798–830, ISSN 2472-1751
Editore:
MIT Press Journals
DOI:
10.1162/netn_a_00202
Autori:
Hashemi, M., Vattikonda, A.N., Sip, V., Diaz-Pier, S., Peyser, A., Wang, H., Guye, M., Bartolomei, F., Woodman, M.M. and Jirsa, V.K.
Pubblicato in:
PLoS computational biology, 2021, ISSN 1553-7358
Editore:
Public Library of Science
DOI:
10.1371/journal.pcbi.1009129
Autori:
Oleksandr V. Popovych, Kyesam Jung, Thanos Manos, Sandra Diaz-Pier, Felix Hoffstaedter, Jan Schreiber, B.T. Thomas Yeo, Simon B. Eickhoff
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NeuroImage, Numero 236, 2021, Pagina/e 118201, ISSN 1053-8119
Editore:
Academic Press
DOI:
10.1016/j.neuroimage.2021.118201
Autori:
Koval, Igor; Bône, Alexandre; Louis, Maxime; Lartigue, Thomas; Bottani, Simona; Marcoux, Arnaud; Samper-Gonzalez, Jorge; Burgos, Ninon; Charlier, Benjamin; Bertrand, Anne; Epelbaum, Stéphane; Colliot, Olivier; Allassonnière, Stéphanie; Durrleman, Stanley
Pubblicato in:
EISSN: 2045-2322, Numero 2, 2021, ISSN 2045-2322
Editore:
Nature Publishing Group
DOI:
10.1038/s41598-021-87434-1
Autori:
Bône, Alexandre; Colliot, Olivier; Durrleman, Stanley
Pubblicato in:
International Journal of Computer Vision, Numero 2, 2020, ISSN 0920-5691
Editore:
Kluwer Academic Publishers
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10.1007/s11263-020-01343-w
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Birkenbihl, Colin; Salimi, Yasamin; Fröhlich, Holger
Pubblicato in:
Fraunhofer SCAI, Numero 2, 2021, ISSN 1552-5279
Editore:
Wiley
DOI:
10.1002/alz.12387
Autori:
Kyesam Jung; Simon B. Eickhoff; Oleksandr V. Popovych
Pubblicato in:
NeuroImage, Numero 237, 2021, Pagina/e 118176, ISSN 1053-8119
Editore:
Academic Press
DOI:
10.1016/j.neuroimage.2021.118176
Autori:
Demian Battaglia; Thomas Boudou; Thomas Boudou; Enrique C. A. Hansen; Enrique C. A. Hansen; Diego Lombardo; Sabrina Chettouf; Sabrina Chettouf; Andreas Daffertshofer; Anthony R. McIntosh; Joelle Zimmermann; Petra Ritter; Viktor K. Jirsa
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"NeuroImage, Elsevier, 2020, 222, pp.117156. ⟨10.1016/j.neuroimage.2020.117156⟩", Numero 2, 2020, ISSN 1053-8119
Editore:
Academic Press
DOI:
10.1016/j.neuroimage.2020.117156
Autori:
Michael Hanke; Franco Pestilli; Adina Wagner; Christopher J. Markiewicz; Jean-Baptiste Poline; Yaroslav O. Halchenko
Pubblicato in:
Neuroforum, 2021, ISSN 2363-7013
Editore:
Walter de Gruyter GmbH
DOI:
10.1515/nf-2020-0037
Autori:
Yaroslav O. Halchenko, Kyle Meyer, Benjamin Poldrack, Debanjum Singh Solanky, Adina S. Wagner, Jason Gors, Dave MacFarlane,Dorian Pustina, Vanessa Sochat, Satrajit S. Ghosh, Christian Mönch, Christopher J. Markiewicz, Laura Waite, Ilya Shlyakhter,Alejandro de la Vega, Soichi Hayashi, Christian Olaf Häusler, Jean-Baptiste Poline, Tobias Kadelka, Kusti Skytén, DorotaJ arecka, David Kennedy, Ted S
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The Journal of Open Source Software, 2021, ISSN 2475-9066
Editore:
IGI Global Publishing
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10.21105/joss.03262
Autori:
Monica Roascio, Andrea Canessa, Rosella Trò, Pietro Mattioli, Francesco Famà, Laura Giorgetti, Nicola Girtler, Beatrice Orso, Silvia Morbelli, Flavio Nobili, Dario Arnaldi, Gabriele Arnulfo
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Sleep, 2021, ISSN 0161-8105
Editore:
The American Academy of Sleep Medicine
DOI:
10.1093/sleep/zsab232
Autori:
Diogo Santos-Pata; Adrián F. Amil; Ivan Georgiev Raikov; César Rennó-Costa; Anna Mura; Ivan Soltesz; Paul F.M.J. Verschure
Pubblicato in:
iScience, Vol 24, Iss 5, Pp 102501- (2021), Numero 2, 2021, ISSN 2589-0042
Editore:
Cell Press
DOI:
10.1016/j.isci.2021.102501
Autori:
Jérôme Dockès; Russell A. Poldrack; Romain Primet; Hande Gözükan; Tal Yarkoni; Fabian M. Suchanek; Bertrand Thirion; Gaël Varoquaux
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2020, Numero 2, 2020, ISSN 2050-084X
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eLife Sciences Publications
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10.7554/elife.53385
Autori:
Franziska Scheibe; Franziska Scheibe; Wolf-Julian Neumann; Catharina Lange; Michael Scheel; Christian Furth; Martin Köhnlein; Philipp Mergenthaler; Jörg Schultze‐Amberger; Paul Triebkorn; Petra Ritter; Andrea A. Kühn; Andreas Meisel
Pubblicato in:
European Journal of Neurology, Numero 2, 2021, ISSN 1468-1331
Editore:
Wiley
DOI:
10.1111/ene.14326
Autori:
Eickhoff, Claudia R; Hoffstaedter, Felix; Caspers, Julian; Reetz, Kathrin; Mathys, Christian; Dogan, Imis; Amunts, Katrin; Schnitzler, Alfons; Eickhoff, Simon B
Pubblicato in:
Brain communications, 2021, ISSN 2632-1297
Editore:
Oxford University Press on behalf of the Guarantors of Brain
DOI:
10.1093/braincomms/fcab191
Autori:
Thomas Lartigue; Simona Bottani; Stephanie Baron; Olivier Colliot; Stanley Durrleman; Stéphanie Allassonnière
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"IEEE Transactions on Pattern Analysis and Machine Intelligence, Institute of Electrical and Electronics Engineers, 2021, 43 (9), pp.3196-3213. ⟨10.1109/TPAMI.2020.2980542⟩", Numero 2, 2021, ISSN 0162-8828
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Institute of Electrical and Electronics Engineers
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10.1109/tpami.2020.2980542
Autori:
F. Scheibe, W. J. Neumann, C. Lange, M. Scheel, C. Furth, M. Köhnlein, P. Mergenthaler, J. Schultze‐Amberger, P. Triebkorn, P. Ritter, A. A. Kühn, A. Meisel
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European Journal of Neurology, 2020, ISSN 1351-5101
Editore:
Blackwell Publishing Inc.
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10.1111/ene.14326
Autori:
Sabrina Chettouf, Laura M. Rueda-Delgado, Ralph de Vries, Petra Ritter, Andreas Daffertshofer
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Kelly Shen, Gleb Bezgin, Michael Schirner, Petra Ritter, Stefan Everling, Anthony R. McIntosh
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Scientific Data, Numero 6/1, 2019, ISSN 2052-4463
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Springer Nature
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Leon Stefanovski, Paul Triebkorn, Andreas Spiegler, Margarita-Arimatea Diaz-Cortes, Ana Solodkin, Viktor Jirsa, Anthony Randal McIntosh, Petra Ritter
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Frontiers in Computational Neuroscience, Numero 13, 2019, ISSN 1662-5188
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NeuroImage, Numero 213, 2020, Pagina/e 116738, ISSN 1053-8119
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Springer Nature
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Scientific Reports, Numero 30, 2022, ISSN 2045-2322
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Nature Publishing Group
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Colin Birkenbihl; Colin Birkenbihl; Yasamin Salimi; Yasamin Salimi; Daniel Domingo-Fernández; Daniel Domingo-Fernández; Simon Lovestone; Holger Fröhlich; Holger Fröhlich; Martin Hofmann-Apitius; Martin Hofmann-Apitius; Japanese Alzheimer's Disease Neuroimaging Initiative
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Wiley
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Fulvia Palesi; Fulvia Palesi; Roberta Maria Lorenzi; Claudia Casellato; Petra Ritter; Petra Ritter; Viktor Jirsa; Claudia A.M. Gandini Wheeler-Kingshott; Claudia A.M. Gandini Wheeler-Kingshott; Claudia A.M. Gandini Wheeler-Kingshott; Egidio D’Angelo; Egidio D’Angelo
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Editore:
Frontiers Research Foundation
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10.3389/fncel.2020.00240
Autori:
Leon Stefanovski; Leon Stefanovski; Paul Triebkorn; Paul Triebkorn; Andreas Spiegler; Andreas Spiegler; Margarita-Arimatea Diaz-Cortes; Margarita-Arimatea Diaz-Cortes; Margarita-Arimatea Diaz-Cortes; Ana Solodkin; Viktor Jirsa; Anthony Randal McIntosh; Petra Ritter; Petra Ritter; Petra Ritter; for the Alzheimer's Disease Neuroimaging Initiative
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Frontiers Research Foundation
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Editore:
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Autori:
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Numero 2, 2020, ISBN 978-0-879699-41-3
Editore:
Cold Spring Habor Laboratory
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10.1101/2020.03.26.009795
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Paul F. M. J. Verschure; Diogo Santos-Pata
Pubblicato in:
bioRxiv, Numero 7, 2020
Editore:
Cold Spring Harbor Laboratory
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10.1101/2020.01.11.902742
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Lartigue, Thomas; Durrleman, Stanley; Allassonnière, Stéphanie
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2020, Numero 2, 2021, ISSN 2331-8422
Editore:
Cornell University
Autori:
Diogo Santos-Pata, Belen Rubio Ballester, Riccardo Zucca, Carlos Stefano Filho, Sara Regina Almeida, Li Li Min, Gabriela Castellano, Paul FMJ Verschure
Pubblicato in:
medRxiv, 2020
Editore:
CSHL
DOI:
10.1101/2020.01.19.20017996
Autori:
Koval, Igor; Bône, Alexandre; Louis, Maxime; Bottani, Simona; Marcoux, Arnaud; Samper-Gonzalez, Jorge; Burgos, Ninon; CHARLIER, Benjamin; Bertrand, Anne; Epelbaum, Stéphane; Colliot, Olivier; Allassonnière, Stéphanie; Durrleman, Stanley
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2018, Numero 2, 2018
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INRIA
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Sara, Mora; Sumit, Madan; Stephan, Gebel; Mauro, Giacomini
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Fraunhofer SCAI, Numero 1, 2020
Editore:
IOS Press
Autori:
Martin, Lucas; Josse, Julie; Thirion, Bertrand
Pubblicato in:
MICCAI BrainLes 2020 workshop, Oct 2020, Lima, Peru, Numero 1, 2021
Editore:
Springer
DOI:
10.1007/978-3-030-72084-1_9
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