Electronic smart patch system for wireless monitoring of molecular biomarkers for healthcare and well-being

Project Information

ELSAH

Grant agreement ID: 825549

DOI 10.3030/825549

Project closed

EC signature date 5 December 2018

Start date 1 January 2019

End date 31 December 2023

Funded under

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT)

Total cost € 3 976 537,50

EU contribution € 3 976 537,50

Coordinated by

AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH
Austria

Deliverables

Websites, patent fillings, videos etc. (5)

Press release & project website

Press release & project website online (Task 8.3)

Training event 1

Training event 1 Task 84 Biomolecular sensing in the ISF ICL TYN

Training event 2

Training event 2 Task 84 Printed electronics for wearables LEITAT SAR

Training event 3

Training event 3 (Task 8.4): Design and development of microchips for sensing applications (IFAT)

Final press release

Final press release (Task 8.3)

Documents, reports (1)

ELSAH-patch end-user validation report

ELSAH-patch end-user validation report (Task 7.6)

Demonstrators, pilots, prototypes (4)

First flexible printed ELSAH-patches (Vienna demonstrators) available for in-vitro testing
First ELSAH-patches (Graz demonstrators) available for in-vivo testing

First ELSAH-patches available for in-vivo testing (Task 6.5)

First full 2nd generation ELSAH-system demonstrator

First full 2nd generation ELSAHsystem demonstrator Task 63

First full 1st generation ELSAH-system demonstrator

First full 1st generation ELSAH-system demonstrator (Task 6.2)

Publications

Peer reviewed articles (8)

A Perspective on microneedle sensor arrays for continuous monitoring of the body's chemistry

Author(s): Freeman, David Martin Eric; Cass, Anthony
Published in: Applied Physics Letters, Issue 121, 2022, Page(s) 070502 (1-6), ISSN 0003-6951
Publisher: American Institute of Physics
DOI: 10.1063/5.0097040

Detection of Lactate via Amperometric Sensors Modified With Direct Electron Transfer Enzyme Containing PEDOT:PSS and Hydrogel Inks

Author(s): S. Kurzhals, E. Melnik, P. Plata, E. Cihan, P.L. Herzog, A.K.G. Felice, A. Bocchino, C. O'Mahony, G.C. Mutinati, R. Hainberger
Published in: IEEE Sensors Letters, Issue 7 (9), 2023, Page(s) 4503104 - 4503107, ISSN 2475-1472
Publisher: IEEE
DOI: 10.1109/lsens.2023.3307066

Minimally Invasive Electrochemical Patch-Based Sensor System for Monitoring Glucose and Lactate in the Human Body—A Survey-Based Analysis of the End-User’s Perspective

Author(s): Roman Holzer, Wilhelm Bloch, Christian Brinkmann
Published in: Sensors, Issue 20/20, 2020, Page(s) 5761, ISSN 1424-8220
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s20205761

ELSAH (electronic smart patch system for wireless monitoring of molecular biomarkers for healthcare and wellbeing): definition of possible use cases

Author(s): Christian Brinkmann, Wilhelm Bloch, Giorgio C. Mutinati
Published in: Frontiers in Bioengineering and Biotechnology, Issue 11, 2023, Page(s) 1-6, ISSN 2296-4185
Publisher: Frontiers
DOI: 10.3389/fbioe.2023.1166857

Continuous Measurement of Lactate Concentration in Human Subjects through Direct Electron Transfer from Enzymes to Microneedle Electrodes

Author(s): Freeman, David Martin Eric; Ming, Damien K; Wilson, Richard; Herzog, Peter; Schulz, Christopher; Felice, Alfons K G; Chen, Yu-Chih; O'Hare, Danny; Holmes, Alison; Cass, Anthony
Published in: ACS Sensors, Issue 8 (4), 2023, Page(s) 1639 -1647, ISSN 2379-3694
Publisher: ACS Publications
DOI: 10.1021/acssensors.2c02780

Novel Approach for the Immobilization of Cellobiose Dehydrogenase in PEDOT:PSS Conductive Layer on Planar Gold Electrodes

Author(s): Esra Cihan, Eva Melnik, Steffen Kurzhals, Paulina Plata, Giorgio C. Mutinati, Rainer Hainberger, Alfons K.G. Felice, Christopher Schulz, Peter Lieberzeit
Published in: Chemosensors, Issue 12 (36), 2024, Page(s) 1-15, ISSN 2227-9040
Publisher: MDPI
DOI: 10.3390/chemosensors12030036

A Holistic Presentation of 3-Electrode Potentiostat Measurement Data: The Hexa-Region Plot

Author(s): Inge Siegl, Norbert Sailer, Christoph Steffan
Published in: Journal of The Electrochemical Society, Issue 170, 2023, Page(s) 073507 (1-13), ISSN 0013-4651
Publisher: Electrochemical Society, Inc.
DOI: 10.1149/1945-7111/acd664

Real-time continuous measurement of lactate through a minimally invasive microneedle patch: a phase I clinical study

Author(s): Ming, DK; Jangam, S; Gowers, SAN; Wilson, R; Freeman, DME; Boutelle, MG; Cass, AEG; O’Hare, D; Holmes, AH
Published in: BMJ Innovations, Issue 8 (2), 2022, Page(s) 87-94, ISSN 2055-8074
Publisher: BMJ
DOI: 10.1136/bmjinnov-2021-000864

Conference proceedings (2)

Development and Characterization of Passivation Methods for Microneedle-based Biosensors

Author(s): Andrea, Bocchino; Sofia Rodrigues, Teixeira; Simone, Iadanza; Eva, Melnik; Steffen, Kurzhals; Giorgio C, Mutinati; Conor, O'Mahony
Published in: 2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), Issue 1, 2022, Page(s) 1275–1278
Publisher: IEEE
DOI: 10.1109/embc48229.2022.9871005

A Floating Differential DAC Expands the Output Voltage Range for Electrochemical Measurements

Author(s): Christoph Steffan; Markus Haberler; Inge Siegl; Norbert Sailer
Published in: 2021 International Conference on Converging Technology in Electrical and Information Engineering (ICCTEIE), Issue 1, 2021, Page(s) 142-146, ISBN 978-1-6654-0081-7
Publisher: IEEE