Project description
A natural way to keep chickens healthy
Salmonella and Escherichia coli are the commonest infectious pathogens in poultry. Antibiotics are extensively used in farms to treat infections; however, their overuse has caused a rise in antimicrobial resistance in both animal and humans. To mitigate this effect, the EU-funded PHAGOVET project proposes cost-effective biocide and technological food additive products based on bacteriophages to target and kill bacteria. It will be the first phage-based solution to naturally control both bacteria in poultry production while avoiding side effects and residues associated with antibiotic use. This natural alternative to antibiotics will benefit the EU’s poultry and egg production – among the largest in the world.
Objective
The Phagovet project is devised to satisfy market demand for a more secure and reliable solution to control Salmonella and E. coli infections in poultry farms. With more than 40,000 poultry farms, the European Union (EU-28) is the forth world´s top producers in poultry meat (13.1 million tons, 2014) and the second largest egg producer (>11 million tons, 2014). The European poultry industry employs 302,000 staff across Europe and has an annual turnover of €30 B, being then of significant economic importance. To date, avian colibacillosis and salmonellosis are considered the main bacterial infections in the poultry sector having an important economic impact worldwide. Furthermore, EFSA estimated overall economic burden of human salmonellosis at €3B/year. Finally, the overuse of antibiotic in farming has caused a rise in antimicrobial resistance 700,000 people die annually from drug resistant infections and it is estimated that this number will rise to 10 million by 2050. In response to the unmet need, Phagovet proposes a cost-effective alternative to antibiotics against Salmonella and E. coli. Phagovet consists of a biocide and two technological food additive products based on selected bacteriophages able to kill the target bacteria. Phagovet will be the first phage-based solution to naturally and effectively control both bacteria in poultry production while avoiding side effects and residues associated to antibiotic use. It will reduce Sallmonella infections by 20% and reduce the use of antibiotics on E. coli by 50%. Thus, Phagovet provides a promising effective control measure for a concerning problem for poultry farmers and for human health. The successful market launch of Phagovet will enable members of the Consortium to consolidate their position in the Animal Health, Food Safety and Environmental Control markets and commercialize the product worldwide, reaching €17.76M profit at the end of 2026.
Fields of science
Not validated
Not validated
- medical and health scienceshealth sciencespublic health
- natural sciencesbiological sciencesmicrobiologybacteriology
- natural sciencesbiological sciencesmicrobiologyvirology
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsantibiotics
- medical and health sciencesbasic medicinepharmacology and pharmacydrug resistanceantibiotic resistance
Keywords
Programme(s)
Funding Scheme
IA - Innovation actionCoordinator
3460-021 Tondela
Portugal
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.