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Holistic solution to improve animal food production through deconstructing the biomolecular interactions between feed, gut microorganisms and animals in relation to performance parameters

Descripción del proyecto

Optimización de los animales para la producción humana

Desde los residentes de zonas rurales que tienen gallinas domésticas hasta los granjeros con miles de cabezas de ganado, la salud animal es la principal prioridad. El equipo del proyecto HoloFood, financiado con fondos europeos, empleará un nuevo método hologenómico para estudiar la salud de los animales teniendo en consideración su panorama bioquímico y su microbioma. El equipo del proyecto se centrará en el salmón y el pollo, dos sistemas de animales de cría sumamente importantes. Caracterizará no solo los genomas, transcriptomas y metabolomas de los microorganismos que tienen asociados, sino también la forma en que el microbioma interactúa con los genomas y transcriptomas de los animales del nuevo marco hologenómico en lo que se refiere a índices de rendimiento clave y cuestiones de bienestar animal. Esta información se utilizará para optimizar los suplementos alimenticios adaptándolos al acervo genético y la fase de desarrollo de los animales.

Objetivo

Optimising food production is not only of commercial interest for companies, but with the planet’s population approaching the nine billion mark, also of critical importance for humanity. Animal food production can be optimised by modulating animal-associated microbiomes through the use of feed additives such as prebiotics and probiotics. Previously developed feed additives have not acknowledged the specific means of action of the additives on the microbiome and host organisms, and consequently i) their performance is inconsistent across animals with different genetic background and when grown under different environments, ii) improvement of feed additives is inefficient and costly, and iii) optimal solutions are unlikely to be found without taking a more holistic approach. HoloFood showcases a holistic approach that will improve the efficiency of food production systems by deciphering the molecular and physiological processes triggered by feed additives across animals with different genetic background and grown under different environments. We will use two critically important farmed animal systems as our models -salmon and chicken- and characterise not only their associated microorganisms’ genomes, transcriptomes and metabolomes but also how the microbiome interacts with animals' genomes and transcriptomes within the new holo-omic framework in relation to key performance indices and animal welfare issues. The knowledge generated will be used to optimise feed additive administration strategies of already implemented products by tailoring them to the genetic background and developmental stage of the animals as well as production environment, to improve the quantity, quality and safety of the produced food, as well as sustainability of food production and animal welfare. HoloFood will also serve to raise awareness about the importance of microbiomes in food production, and to establish bridges between companies and academia to foster science-based strategies.

Convocatoria de propuestas

H2020-SFS-2018-2020

Consulte otros proyectos de esta convocatoria

Convocatoria de subcontratación

H2020-SFS-2018-1

Régimen de financiación

IA - Innovation action

Coordinador

KOBENHAVNS UNIVERSITET
Aportación neta de la UEn
€ 3 797 766,00
Dirección
NORREGADE 10
1165 Kobenhavn
Dinamarca

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Región
Danmark Hovedstaden Byen København
Tipo de actividad
Higher or Secondary Education Establishments
Enlaces
Coste total
€ 3 858 827,50

Participantes (10)