Interdisciplinary training network for advancing Organ-on-a-chip technology in Europe

Autores: Mara Lucchetti, Mathilda Kaminska, Aina Kehinde Oluwasegun, Alexander S. Mosig, Paul Wilmes
Publicado en: Current Opinion in Endocrine and Metabolic Research, Edición 2021, Volume 18, 2021, Página(s) 91-101, ISSN 2451-9650
Editor: Elsevier
DOI: 10.1016/j.coemr.2021.03.003

Perspectives for Future Use of Cardiac Microtissues from Human Pluripotent Stem Cells

Autores: Arslan, U.; Orlova, V.V.; Mummery, C.L.
Publicado en: ACS Biomaterials Science and Engineering, Edición 2022, 8, 11,, 2022, Página(s) 4605–4609, ISSN 2373-9878
Editor: ACS
DOI: 10.1021/acsbiomaterials.1c01296

Co-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip model

Autores: Stefanie Deinhardt-Emmer, Knut Rennert, Elisabeth Schicke, Zoltán Cseresnyés, Maximilian Windolph, Sandor Nietzsche, Regine Heller, Fatina Siwczak, Karoline Frieda Haupt, Swen Carlstedt, Michael Schacke, Marc Thilo Figge, Christina Ehrhardt, Bettina Löffler, Alexander S Mosig
Publicado en: Biofabrication, Edición 12/2, 2020, Página(s) 025012, ISSN 1758-5090
Editor: IOP Publishing Ltd
DOI: 10.1088/1758-5090/ab7073

A microphysiological system for studying human bone biology under simultaneous control of oxygen tension and mechanical loading

Autores: Julia Scheinpflug Chris Tina Höfer, Sarah S. Schmerbeck, Matthias Steinfath, Jennifer Doka, Yonatan Afework Tesfahunegn, Norman Violet, Kostja Renko, Konrad Gulich, Thilo John, Marlon R. Schneider, Elisa Wistorf , Gilbert Schönfelder and Frank Schulze
Publicado en: Lab on a Chip, Edición 2023, Volume 15, 2023, Página(s) 3405-3423, ISSN 1473-0197
Editor: Royal Society of Chemistry
DOI: 10.1039/d3lc00154g

Applicability of organ-on-chip systems in toxicology and pharmacology

Autores: Marlon R. Schneider, Michael Oelgeschlaeger, Tanja Burgdorf, Peter van Meer, Peter Theunissen, Anne S. Kienhuis, Aldert H. Piersma & Rob J. Vandebriel
Publicado en: Critical Reviews in Toxicology, Edición 2021, 51(6), 2021, Página(s) 540-554, ISSN 1547-6898
Editor: Taylor & Francis
DOI: 10.1080/10408444.2021.1953439

Autologous Human Immunocompetent White Adipose Tissue-on-Chip

Autores: Julia Rogal, Julia Roosz, Claudia Teufel, Madalena Cipriano, Raylin Xu, Wiebke Eisler, Martin Weiss, Katja Schenke-Layland, Peter Loskill
Publicado en: Advanced Science, Edición 2022, Volume 9(18), 2022, Página(s) 2104451, ISSN 2198-3844
Editor: John Wiley & Sons, Inc.
DOI: 10.1002/advs.202104451

Fusing spheroids to aligned μ-tissues in a heart-on-chip featuring oxygen sensing and electrical pacing capabilities

Autores: Oliver Schneider; Alessia Moruzzi; Stefanie Fuchs; Alina Grobel; Henrike S. Schulze; Torsten Mayr; Peter Loskill
Publicado en: Materials Today Bio , Edición Volume 15, 2022, Página(s) 100280, ISSN 2590-0064
Editor: Elsevier
DOI: 10.1016/j.mtbio.2022.100280

Microphysiological stem cell models of the human heart

Autores: Ulgu Arslan; Alessia Moruzzi; Joanna Nowacka; Christine L. Mummery; Dominik Eckardt; Peter Loskill; Valeria V. Orlova
Publicado en: Materials Today Bio, Edición Volume 14, 2022, 2022, Página(s) 100259, ISSN 2590-0064
Editor: Elsevier
DOI: 10.1016/j.mtbio.2022.100259

Keeping Candida commensal: how lactobacilli antagonize pathogenicity of Candida albicans in an in vitro gut model

Autores: Katja Graf, Antonia Last, Rena Gratz, Stefanie Allert, Susanne Linde, Martin Westermann, Marko Gröger, Alexander S. Mosig, Mark S. Gresnigt, Bernhard Hube
Publicado en: Disease Models & Mechanisms, Edición 12/9, 2019, Página(s) dmm039719, ISSN 1754-8403
Editor: The Company of Biologists Ltd.
DOI: 10.1242/dmm.039719

Intestinal Stem Cell-on-Chip to Study Human Host-Microbiota Interaction

Autores: Fatina Siwczak; Elise Loffet; Mathilda Kaminska; Hristina Koceva; Maxime M. Mahe; Maxime M. Mahe; Maxime M. Mahe; Alexander S. Mosig
Publicado en: Frontiers in Immunology, Edición 2021, Volume 12, 2021, Página(s) 798552, ISSN 1664-3224
Editor: Frontires
DOI: 10.3389/fimmu.2021.798552

Vascularized hiPSC-derived 3D cardiac microtissue on chip

Autores: Ulgu Arslan, Marcella Brescia, Viviana Meraviglia, Dennis Nahon, Ruben van Helden, Marc Vila Cuenca, Jeroen Stein, Francijna E. van den Hil, Berend van Meer, Christine Mummery, Valeria Orlova
Publicado en: Stem Cell Reports, Edición 2023, Volume 18(7), 2023, Página(s) 1394-1404, ISSN 2213-6711
Editor: Cell Press
DOI: 10.1016/j.stemcr.2023.06.001

Three-Dimensional Vessels-on-a-Chip Based on hiPSC-derived Vascular Endothelial and Smooth Muscle Cells

Autores: Bulut, M., Cuenca, M.V., Graaf, M., Hil, F.E., Mummery, C.L., and Orlova, V.V.
Publicado en: Current Protocols, Edición 2022, Volume 2, 2022, Página(s) e564, ISSN 2691-1299
Editor: John Wiley & Sons, Inc.
DOI: 10.1002/cpz1.564

A versatile and customizable low-cost 3D-printed open standard for microscopic imaging

Autores: Benedict Diederich, René Lachmann, Swen Carlstedt, Barbora Marsikova, Haoran Wang, Xavier Uwurukundo, Alexander S. Mosig, Rainer Heintzmann
Publicado en: Nature Communications, Edición 11/1, 2020, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-020-19447-9

On-chip analysis of glycolysis and mitochondrial respiration in human induced pluripotent stem cells

Autores: Fuchs S, Helden RWJ van, Wiendels M, Graaf MNS de, Orlova VV, Mummery CL, Meer BJ van, Mayr T
Publicado en: Materials Today Bio, Edición 2022, Volume 17(15), 2022, Página(s) 100475, ISSN 2590-0064
Editor: Elsevier
DOI: 10.1016/j.mtbio.2022.100475

Optical glucose sensor for microfluidic cell culture systems

Autores: Stefanie Fuchs, Veronika Rieger, Anders Ø. Tjell, Sarah Spitz, Konstanze Brandauer, Roland Schaller-Ammann, Jürgen Feiel, Peter Ertl, Ingo Klimant, Torsten Mayr
Publicado en: Biosensors and Bioelectronics, Edición 2023, Volume 237, 2023, Página(s) 115491, ISSN 1873-4235
Editor: Elsevier
DOI: 10.1016/j.bios.2023.115491

Integration of immune cells in organs-on-chips: a tutorial

Autores: Van Os L., Engelhardt B., Guenat OT.
Publicado en: Frontiers in Bioengineering and Biotechnology, Edición 2023, Volume 11, 2023, Página(s) 1191104, ISSN 2296-4185
Editor: Frontires
DOI: 10.3389/fbioe.2023.1191104

Studying metabolism with multi-organ chips: new tools for disease modelling, pharmacokinetics and pharmacodynamics

Autores: Tanvi Shroff, Kehinde Aina, Christian Maass, Madalena Cipriano, Joeri Lambrecht, Frank Tacke, Alexander Mosig and Peter Loskill
Publicado en: Open Biology, Edición 2022, Volume 12(3), 2022, Página(s) 210333, ISSN 2046-2441
Editor: Royal Society Publishing
DOI: 10.1098/rsob.210333

A microfluidic chip carrier including temperature control and perfusion system for long-term cell imaging

Autores: Federico Cantoni, Gabriel Werr, Laurent Barbe, Ana Maria Porras, Maria Tenje
Publicado en: HardwareX, Edición 2021, Volume 10, 2021, Página(s) e00245, ISSN 2468-0672
Editor: Elsevier
DOI: 10.1016/j.ohx.2021.e00245

Training the next generation of researchers in the Organ-on-Chip field

Autores: Alessia Moruzzi; Tanvi Shroff; Silke Keller; Peter Loskill; Madalena Cipriano
Publicado en: Education Sciences, Edición 2023 Volume 13(2), 2023, Página(s) 144, ISSN 2227-7102
Editor: MDPI
DOI: 10.1101/2022.08.03.502617

Immune cell extravasation in an organ-on-chip to model lung inflammation.

Autores: van Os L, Yeoh J, Witz G, Ferrari D, Krebs P, Chandorkar Y, Zeinali S, Sengupta A, Guenat OT
Publicado en: European journal of pharmaceutical Sciences, Edición 2023, Volume 187, 2023, Página(s) 106485, ISSN 1879-0720
Editor: Elsevier
DOI: 10.1016/j.ejps.2023.106485

Staphylococcus aureus Lung Infection Results in Down-Regulation of Surfactant Protein-A Mainly Caused by Pro-Inflammatory Macrophages

Autores: Elisabeth Schicke, Zoltán Cseresnyés, Knut Rennert, Vanessa Vau, Karoline Frieda Haupt, Franziska Hornung, Sandor Nietzsche, Fatina Swiczak, Michaela Schmidtke, Brigitte Glück, Mirijam Koch, Michael Schacke, Regine Heller, Alexander S. Mosig, Marc Thilo Figge, Christina Ehrhardt, Bettina Löffler, Stefanie Deinhardt-Emmer
Publicado en: Microorganisms, Edición 8/4, 2020, Página(s) 577, ISSN 2076-2607
Editor: MDPI
DOI: 10.3390/microorganisms8040577

In-Line Analysis of Organ-on-Chip Systems with Sensors: Integration, Fabrication, Challenges, and Potential

Autores: Stefanie Fuchs, Sofia Johansson, Anders Ø. Tjell, Gabriel Werr, Torsten Mayr, and Maria Tenje
Publicado en: ACS Biomaterials Science & Engineering, Edición 2021, Volume 7(7), 2021, Página(s) 2926-2948, ISSN 2373-9878
Editor: ACS
DOI: 10.1021/acsbiomaterials.0c01110

A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies

Autores: Maurer, M., Gresnigt, M. S., Last, A., Wollny, T., Berlinghof, F., Pospich, R., Cseresnyes, Z., Medyukhina, A., Graf, K., Gröger, M., Raasch, M., Siwczak, F., Nietsche, S., Jacobsen, I. D., Figge, M. T., Hube, B.m Huber, O., Mosig, A. S.
Publicado en: Biomaterials, Edición 2019, Volume 220, 2019, Página(s) 119396, ISSN 1878-5905
Editor: Elsevier
DOI: 10.1016/j.biomaterials.2019.119396

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