Sweeteners and sweetness enhancers: Impact on health, obesity, safety and sustainability

Deliverables

Consumer derived typology on S&SEs report

Summary of consumer derived typology of S&SEs arising from qualitative interviews

Summary of analysis arising from data mining of discussions of SSEs on social media platforms

Inventory of gender equality and diversity of partners and stakeholders

Report on the assessment of the regulatory framework for new S&SEs introduction and how this may be optimised to stimulate market uptake of new, healthy and sustainable S&SEs by industry

Summary report on examination of the existing regulatory framework for the approval and use of SSEs in food

Stakeholder analysis report (redacted for publication with full version including potentially sensitive data available on request) identifying and categorising European publics/stakeholders interested in the role of S&SEs in healthy diets and sustainable

Overview of interest and influence of stakeholders and publics

Updated dissemination plan

Overview of updated dissemination plan

Life Cycle inventory data and results consortium approved and disseminated to open source platforms.

Summary report on distribution of LCA/LCSA data through open access platforms

Cross-European stakeholder perceptions of S&SEs report

Report summarising results of Cross European Survey assessing stakeholder perceptions

Report on methodologies specific for Phase 2: expected and sensory specific satiety, gut and urine biomarkers, gut microbiota, eating behaviour (UEM); brain activity (fMRI); microbiological safety (challenge test)

Overview of phase 2 specific methodologies

Media analysis report

Summary of desk based review of print and online media

Post-award full impact plan

Overview of impact plan developed using a logic model

Decision support tool

Results achieved in work packages 1-6 will be condensed into a decision-making framework for the responsible development and use of sweeteners and sweetness flavour enhancers. The draft framework will be revised as a result of stakeholder workshop outcomes. The final framework tool will be disseminated to all stakeholders

Gender action plan

Summary report of gender action plan

Synthesis report on of Stakeholder perceptions of S&SEs and identification of barriers to and opportunities for increased S&SEs use

Summary report on decision-making framework

Report on methodologies common to Phase 1 and Phase 2 : satiation/satiety and food intake measures; preference/consumer perception questionnaires; anthropometry, chronic disease risk factor and physical activity measures; post-prandial biochemistry and s

Overview of trial (phase 1 and phase 2) methodologies

Suite of classic dissemination products

We will produce leaflets and press releases and will convene stakeholder workshops to disseminate and enable dialogue about project findings. A final workshop/conference at project end will be organised for target audiences. A summary of the project results will be made available for stakeholders before the end of the project.

Estimation of population attributable risks for S&SE

Summary assessment of impact of replacing sugars with S&SEs on disease risk and mortality

Publications

Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEET beverages trial

Author(s): Eva Almiron-Roig; Santiago Navas-Carretero; Gabriele Castelnuovo; Louise Kjølbæk; Ana Romo-Hualde; Mie Normand; Niamh Maloney; Charlotte A. Hardman; Charo E. Hodgkins; Hariklia Moshoyiannis; Graham Finlayson; Corey Scott; Monique M. Raats; Joanne A. Harrold; Anne Raben; Jason C.G. Halford; J. Alfredo Martínez
Published in: Appetite, Issue 3, 2023, ISSN 0195-6663
Publisher: Elsevier BV
DOI: 10.1016/j.appet.2023.106515

The SWEET project

Author(s): Novita D. Naomi; Joy Ngo; Elske M. Brouwer-Brolsma; Marion E. C. Buso; Sabita S. Soedamah-Muthu; Carmen Pérez-Rodrigo; Joanne A. Harrold; Jason C. G. Halford; Anne Raben; Johanna M. Geleijnse; Lluis Serra-Majem; Edith J. M. Feskens
Published in: Nutrition & Diabetes, Issue 1, 2023, Page(s) 1-10, ISSN 2044-4052
Publisher: Nature publishing
DOI: 10.1038/s41387-023-00237-3

Relative validity of habitual sugar and low/no calorie sweetener consumption assessed by food frequency questionnaire, multiple 24h dietary recalls and urinary biomarkers: an observational study within the SWEET project

Author(s): Marion EC Buso; Hendriek C Boshuizen; Novita D Naomi; Walid Maho; Marlier Diepeveen-de Bruin; Michiel GJ Balvers; Jeanne HM de Vries; Joanne A Harrold; Jason CG Halford; Anne Raben; Edith JM Feskens; Elske M Brouwer-Brolsma
Published in: The American Journal of Clinical Nutrition, 2024, Page(s) 546-559, ISSN 0002-9165
Publisher: American Society for Clinical Nutrition, Inc.
DOI: 10.1016/j.ajcnut.2023.11.019

the SWEET project

Author(s): Louise Kjølbæk; Yannis Manios; Ellen E Blaak; J. Alfredo Martínez; Edith J M Feskens; Graham Finlayson; Sabina S H Andersen; Kyriakos Reppas; Santiago Navas-Carretero; Tanja C Adam; Charo E Hodgkins; Marta del Álamo; Tony Lam; Hariklia Moshoyiannis; Jason C G Halford; Joanne A Harrold; Anne Raben
Published in: BMJ Open, Issue 9, 2022, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2022-061075

Life cycle assessment of the sweetness enhancer thaumatin (E(57) produced from Thaumatococcus daniellii fruit foraged from West Africa: The SWEET project

Author(s): J.Suckling; S.Morse; R.Murphy; S.AStley; C.Boy: J.C.G.Halford; J.A.Harrold: A, Le-Bail; E.Koukouna; H.Musinovic; A.Raben; M.Roe; J.Scholten; C.Scott; C.Westbroek
Published in: Journal of cleaner production, 2023, ISSN 0959-6526
Publisher: Elsevier BV
DOI: 10.1016/j.jclepro.2023.137226

Development and validation of a UPLC-MS/MS method for the quantification of sugars and non-nutritive sweeteners in human urine

Author(s): Diepeveen-de Bruin, Marlies; Maho, Walid; Buso, Marion E.C.; Naomi, Novita D.; Brouwer-Brolsma, Elske M.; Feskens, Edith J.M.; Balvers, Michiel G.J.
Published in: Journal of Chromatography B, 2023, Page(s) 123741, ISSN 1570-0232
Publisher: Elsevier BV
DOI: 10.1016/j.jchromb.2023.123741

Environmental life cycle assessment of production of the non-nutritive sweetener sucralose (E955) derived from cane sugar produced in the United States of America: The SWEET project

Author(s): E. Blenkley; J. Suckling; S. Morse; R. Murphy; M. Raats; S. Astley; J. C. G. Halford; J. A. Harrold; A. Le-Bail; E. Koukouna; H. Musinovic; A. Raben; M. Roe; J. Scholten; C. Scott; C. Westbroek
Published in: The International Journal of Lifecycle Assessment, 2023, ISSN 0948-3349
Publisher: Springer Verlag
DOI: 10.1007/s11367-023-02228-z

Environmental life cycle assessment of product of the non-nutritive sweeteners aspartame (E951) and neotame (E961) from chemical processes:m The SWEET project

Author(s): J.Suckling; S.Morse; R.Murphy; M.Raats; S.Astley; J.C.G.Halford; J.A.Harrold, A.Le-Bail; E.koukouna, H.Musinovic; A.Raben; M.Roe; J.Scholten; C.SCott; C.Westbroek
Published in: Journal of cleaner production, 2023, ISSN 0959-6526
Publisher: Elsevier BV
DOI: 10.1016/j.jclepro.2023.138854

Association of sweetened beverages consumption with all-cause mortality risk among Dutch adults : the Lifelines Cohort Study (the SWEET project)

Author(s): Novita D. Naomi; Elske M. Brouwer-Brolsma; Marion E. C. Buso; Sabita S. Soedamah-Muthu; Joanne A. Harrold; Jason C. G. Halford; Anne Raben; Johanna M. Geleijnse; Edith J. M. Feskens
Published in: European Journal of Nutrition, Issue 4, 2022, ISSN 1436-6215
Publisher: Springer
DOI: 10.1007/s00394-022-03023-6

SWEET substudy

Author(s): Pang, Michelle D.; Bastings, Jacco J. A. J.; Op den Kamp‐Bruls, Yvonne M. H.; Harrold, Joanne A.; Kjølbæk, Louise; Halford, Jason C. G.; Adam, Tanja C. M.; Raben, Anne; Schrauwen‐Hinderling, Vera B.; Goossens, Gijs H.; Blaak, Ellen E.
Published in: Obesity, Issue 10, 2023, ISSN 1930-7381
Publisher: Wiley-Blackwell
DOI: 10.1002/oby.23773

Protocol for a multi-centre intervention to study short and medium-term effects of sweeteners on appetite-related behaviour, physiology, and health.

Author(s): B. O’Hara; D. O’Connor; K. Beaulieu; E. Almiron-Roig; J.A. Martinez; J.C.G. Halford; J. Harrold; A. Raben; C. Hardman; J.-A. Nazarre; G. Finlayson; C. Gibbons
Published in: Appetite, Issue 6, 2022, ISSN 0195-6663
Publisher: Elsevier BV
DOI: 10.1016/j.appet.2022.106255

Impact of Maltitol and Sorbitol on Technological and Sensory Attributes of Biscuits.

Author(s): Mathilde Roze; Doina Crucean; Guénaëlle Diler; Cécile Rannou; Clement Cataneo; Camille Jonchère; Alain Le-Bail; Patricia Le-Bail
Published in: Foods, Issue 1, 2021, ISSN 2304-8158
Publisher: MDPI
DOI: 10.3390/foods10112545

The SWEET project

Author(s): Marion E. C. Buso; Elske M. Brouwer-Brolsma; Novita D. Naomi; Joy Ngo; Sabita S. Soedamah-Muthu; Christina Mavrogianni; Joanne A. Harrold; Jason C. G. Halford; Anne Raben; Johanna M. Geleijnse; Yannis Manios; Luis Serra-Majem; Edith J. M. Feskens
Published in: European Journal of Nutrition, Issue 3, 2023, ISSN 1436-6207
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00394-023-03192-y

Environmental life cycle assessment of production of the high intensity sweetener steviol glycosides from Stevia rebaudiana leaf grown in Europe: The SWEET project

Author(s): J. Suckling; S. Morse; R. Murphy; S. Astley; J. C. G. Halford; J. A. Harrold; A. Le-Bail; E. Koukouna; H. Musinovic; J. Perret; A. Raben; M. Roe; J. Scholten; C. Scott; C. Stamatis; C. Westbroek
Published in: International Journal of Life Cycle Assessment, Issue 9, 2023, ISSN 0948-3349
Publisher: Springer Verlag
DOI: 10.1007/s11367-022-02127-9

protocol for a multicentre, cross-over, RCT in people with overweight/obesity - the SWEET Project

Author(s): Catherine Gibbons; Beverley O'Hara; Dominic O’Connor; Charlotte Hardman; Moon Wilton; Joanne A Harrold; Eva Almiron-Roig; Santiago Navas-Carretero; Charo E Hodgkins; Julie Anne Nazare; Maud Alligier; Jose Alfredo Martínez; Corey Scott; Louise Kjølbæk; Mie Normand; Cécile Rannou; Ellen E Blaak; Edith Feskens; Hariklia Moshoyiannis; Anne Raben; Jason C G Halford; Kristine Beaulieu; Graham Finl
Published in: BMJ Open, Issue 3, 2022, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2022-063903

Acute and two-week effects of neotame, stevia rebaudioside M and sucrose-sweetened biscuits on postprandial appetite and endocrine response in adults with overweight/obesity-a randomised crossover trial from the SWEET consortium

Author(s): Catherine Gibbons, Kristine Beaulieu, Eva Almiron-Roig, Santiago Navas-Carretero, J Alfredo Martínez, Beverley O'Hara, Dominic O'Connor, Julie-Anne Nazare, Alain Le Bail, Cécile Rannou, Charlotte Hardman, Moon Wilton, Louise Kjølbæk, Corey Scott, Hariklia Moshoyiannis, Anne Raben, Joanne A Harrold, Jason C G Halford, Graham Finlayson
Published in: EBioMedicine, 2024, ISSN 2352-3964
Publisher: Elsevier BV
DOI: 10.1016/j.ebiom.2024.105005

A rational review on the effects of sweeteners and sweetness enhancers on appetite, food reward and metabolic/adiposity outcomes in adults

Author(s): Dominic O'Connor, Michelle Pang, Gabriele Castelnuovo, Graham Finlayson, Ellen Blaak, Catherine Gibbons, Santiago Navas-Carretero, Eva Almiron-Roig, Jo Harrold, Anne Raben, J. Alfredo Martinez
Published in: Food & Function, Issue 12/2, 2020, Page(s) 442-465, ISSN 2042-6496
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0fo02424d

Dose-Response and Substitution Analyzes of Sweet Beverage Consumption and Body Weight in Dutch Adults: The Lifelines Cohort Study

Author(s): Marion E. C. Buso; Elske M. Brouwer-Brolsma; Novita D. Naomi; Joanne A. Harrold; Jason C. G. Halford; Jason C. G. Halford; Anne Raben; Edith J. M. Feskens
Published in: Frontiers in Nutrition, Issue 6, 2022, ISSN 2296-861X
Publisher: Frontiers Media
DOI: 10.3389/fnut.2022.889042

Deliverables

Publications

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