Hanover experimental lung research project

The role of vasculature and angiogenesis in respiratory diseases

Autores: Maximilian Ackermann, Christopher Werlein, Edith Plucinski, Sophie Leypold, Mark P. Kühnel, Stijn E. Verleden, Hassan A. Khalil, Florian Länger, Tobias Welte, Steven J. Mentzer, Danny D. Jonigk
Publicado en: Angiogenesis, Edición 27, 2024, Página(s) 293-310, ISSN 0969-6970
Editor: Kluwer Academic Publishers
DOI: 10.1007/s10456-024-09910-2

Non-invasive screening for subclinical liver graft injury in adults via donor-specific anti-HLA antibodies

Autores: Anne Höfer, Danny Jonigk, Björn Hartleben, Murielle Verboom, Michael Hallensleben, Michael P. Manns, Elmar Jaeckel, Richard Taubert
Publicado en: Scientific Reports, Edición 10, 2022, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-020-70938-7

Cigarette smoke alters inflammatory genes and the extracellular matrix — investigations on viable sections of peripheral human lungs

Autores: Helena Obernolte, Monika Niehof, Peter Braubach, Hans-Gerd Fieguth, Danny Jonigk, Olaf Pfennig, Thomas Tschernig, Gregor Warnecke, Armin Braun, Katherina Sewald
Publicado en: Cell and Tissue Research, Edición 387, 2023, Página(s) 249-260, ISSN 0302-766X
Editor: Springer Verlag
DOI: 10.1007/s00441-021-03553-1

Reconstruction of the miR-506-Quaking axis in Idiopathic Pulmonary Fibrosis using integrative multi-source bioinformatics

Autores: Stevan D. Stojanović, Maximilian Fuchs, Chunguang Liang, Kevin Schmidt, Ke Xiao, Annette Just, Angelika Pfanne, Andreas Pich, Gregor Warnecke, Peter Braubach, Christina Petzold, Danny Jonigk, Jörg H. W. Distler, Jan Fiedler, Thomas Thum, Meik Kunz
Publicado en: Scientific Reports, Edición 11, 2022, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-021-89531-7

COVID-19: Auswirkungen auf Lunge und Herz

Autores: Maximilian Ackermann, Christopher Werlein, Florian Länger, Mark P. Kühnel, Danny D. Jonigk
Publicado en: Der Pathologe, Edición 42, 2021, Página(s) 164-171, ISSN 0172-8113
Editor: Springer Verlag
DOI: 10.1007/s00292-021-00918-9

Comprehensive three‐dimensional morphology of neoangiogenesis in pulmonary veno‐occlusive disease and pulmonary capillary hemangiomatosis

Autores: Lavinia Neubert, Paul Borchert, Hoen‐Oh Shin, Friedemann Linz, Willi L Wagner, Gregor Warnecke, Florian Laenger, Axel Haverich, Helge Stark, Marius M Hoeper, Mark Kuehnel, Maximilian Ackermann, Danny Jonigk
Publicado en: The Journal of Pathology: Clinical Research, Edición 5, 2023, Página(s) 108-114, ISSN 2056-4538
Editor: Wiley
DOI: 10.1002/cjp2.125

Multilamellated Basement Membranes in the Capillary Network of Alveolar Capillary Dysplasia

Autores: Jan C. Kamp, Lavinia Neubert, Jonas C. Schupp, Peter Braubach, Christoph Wrede, Florian Laenger, Tim Salditt, Jakob Reichmann, Tobias Welte, Arjang Ruhparwar, Fabio Ius, Nicolaus Schwerk, Anke K. Bergmann, Sandra von Hardenberg, Matthias Griese, Christina Rapp, Karen M. Olsson, Jan Fuge, Da-Hee Park, Marius M. Hoeper, Danny D. Jonigk, Lars Knudsen, Mark P. Kuehnel
Publicado en: The American Journal of Pathology, Edición 194, 2024, Página(s) 180-194, ISSN 0002-9440
Editor: American Society for Investigative Pathology
DOI: 10.1016/j.ajpath.2023.10.012

Targeting cyclin-dependent kinases for the treatment of pulmonary arterial hypertension

Autores: Astrid Weiss, Moritz Christian Neubauer, Dinesh Yerabolu, Baktybek Kojonazarov, Beate Christiane Schlueter, Lavinia Neubert, Danny Jonigk, Nelli Baal, Clemens Ruppert, Peter Dorfmuller, Soni Savai Pullamsetti, Norbert Weissmann, Hossein-Ardeschir Ghofrani, Friedrich Grimminger, Werner Seeger, Ralph Theo Schermuly
Publicado en: Nature Communications, Edición 10, 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-019-10135-x

IBEX: an iterative immunolabeling and chemical bleaching method for high-content imaging of diverse tissues

Autores: Andrea J. Radtke, Colin J. Chu, Ziv Yaniv, Li Yao, James Marr, Rebecca T. Beuschel, Hiroshi Ichise, Anita Gola, Juraj Kabat, Bradley Lowekamp, Emily Speranza, Joshua Croteau, Nishant Thakur, Danny Jonigk, Jeremy L. Davis, Jonathan M. Hernandez, Ronald N. Germain
Publicado en: Nature Protocols, Edición 17, 2024, Página(s) 378-401, ISSN 1754-2189
Editor: Nature Publishing Group
DOI: 10.1038/s41596-021-00644-9

The fatal trajectory of pulmonary COVID-19 is driven by lobular ischemia and fibrotic remodelling

Autores: Maximilian Ackermann, Jan C. Kamp, Christopher Werlein, Claire L. Walsh, Helge Stark, Verena Prade, Rambabu Surabattula, Willi L. Wagner, Catherine Disney, Andrew J. Bodey, Thomas Illig, Diana J. Leeming, Morten A. Karsdal, Alexandar Tzankov, Peter Boor, Mark P. Kühnel, Florian P. Länger, Stijn E. Verleden, Hans M. Kvasnicka, Hans H. Kreipe, Axel Haverich, Stephen M. Black, Axel Walch, Paul Taff
Publicado en: eBioMedicine, Edición 85, 2022, Página(s) 104296, ISSN 2352-3964
Editor: Elsevier BV
DOI: 10.1016/j.ebiom.2022.104296

Imaging intact human organs with local resolution of cellular structures using hierarchical phase-contrast tomography

Autores: C. L. Walsh, P. Tafforeau, W. L. Wagner, D. J. Jafree, A. Bellier, C. Werlein, M. P. Kühnel, E. Boller, S. Walker-Samuel, J. L. Robertus, D. A. Long, J. Jacob, S. Marussi, E. Brown, N. Holroyd, D. D. Jonigk, M. Ackermann, P. D. Lee
Publicado en: Nature Methods, Edición 18, 2023, Página(s) 1532-1541, ISSN 1548-7091
Editor: Nature Publishing Group
DOI: 10.1038/s41592-021-01317-x

Microvascular placental alterations in maternal COVID-19

Autores: Maximilian Ackermann, Danny D. Jonigk
Publicado en: American Journal of Obstetrics and Gynecology, Edición 226, 2022, Página(s) 135-136, ISSN 0002-9378
Editor: Mosby Inc.
DOI: 10.1016/j.ajog.2021.06.098

Alveolar Vascular Remodeling in Nonspecific Interstitial Pneumonia: Replacement of Normal Lung Capillaries with COL15A1-Positive Endothelial Cells

Autores: Jonas C. Schupp, Edward P. Manning, Maurizio Chioccioli, Jan C. Kamp, Leonard Christian, Changwan Ryu, Erica Herzog, Mark P. Kühnel, Antje Prasse, Naftali Kaminski, Danny D. Jonigk, Robert J. Homer, Lavinia Neubert, Fabio Ius, Aurélien stringJustet, Lida P. Hariri, Benjamin Seeliger, Tobias Welte, Rachel S. Knipe, Jens Gottlieb
Publicado en: American Journal of Respiratory and Critical Care Medicine, Edición 208, 2023, Página(s) 819-822, ISSN 1073-449X
Editor: American Thoracic Society
DOI: 10.1164/rccm.202303-0544le

Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease

Autores: Melanie Ricke-Hoch, Elisabeth Stelling, Lisa Lasswitz, Antonia P. Gunesch, Martina Kasten, Francisco J. Zapatero-Belinchón, Graham Brogden, Gisa Gerold, Thomas Pietschmann, Virginie Montiel, Jean-Luc Balligand, Federica Facciotti, Emilio Hirsch, Thomas Gausepohl, Husni Elbahesh, Guus F. Rimmelzwaan, Anne Höfer, Mark P. Kühnel, Danny Jonigk, Julian Eigendorf, Uwe Tegtbur, Lena Mink, Michaela Sch
Publicado en: PLOS ONE, Edición 16, 2023, Página(s) e0255335, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0255335

Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging

Autores: Ellen M. Quardokus, Diane C. Saunders, Elizabeth McDonough, John W. Hickey, Christopher Werlein, Christine Surrette, Presha Rajbhandari, Anna Martinez Casals, Hua Tian, Lisa Lowery, Elizabeth K. Neumann, Frida Björklund, Taruna V. Neelakantan, Josh Croteau, Anne E. Wiblin, Jeremy Fisher, April J. Livengood, Karen G. Dowell, Jonathan C. Silverstein, Jeffrey M. Spraggins, Gloria S. Pryhuber, Gail D
Publicado en: Nature Methods, Edición 20, 2023, Página(s) 1174-1178, ISSN 1548-7091
Editor: Nature Publishing Group
DOI: 10.1038/s41592-023-01846-7

Autores: Jan C. Kamp, Naomi N. Kappe, Carlos Fernández Moro, Jan Fuge, Mark P. Kuehnel, Sabine Wrenger, Tobias Welte, Bart van Hoek, Danny D. Jonigk, Padmini P. S. J. Khedoe, Pavel Strnad, Mikael Björnstedt, Jan Stolk, Sabina Janciauskiene, Antal Nemeth
Publicado en: International Journal of Molecular Sciences, Edición 24, 2023, Página(s) 2485, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24032485

Molecular approach to the classification of chronic fibrosing lung disease—there and back again

Autores: Stijn E. Verleden, Peter Braubach, Mark Kuehnel, Nicolas Dickgreber, Emily Brouwer, Pauline Tittmann, Florian Laenger, Danny Jonigk
Publicado en: Virchows Archiv, Edición 478, 2022, Página(s) 89-99, ISSN 0945-6317
Editor: Springer Verlag
DOI: 10.1007/s00428-020-02964-9

When tissue is the issue: A histological review of chronic lung allograft dysfunction

Autores: Stijn E. Verleden, Jan Von der Thüsen, Antoine Roux, Emily S. Brouwers, Peter Braubach, Mark Kuehnel, Florian Laenger, Danny Jonigk
Publicado en: American Journal of Transplantation, Edición 20, 2023, Página(s) 2644-2651, ISSN 1600-6135
Editor: Blackwell Publishing Inc.
DOI: 10.1111/ajt.15864

Novel Insight into Pulmonary Fibrosis and Long COVID

Autores: Jan C. Kamp, Christopher Werlein, Edith K. J. Plucinski, Lavinia Neubert, Tobias Welte, Peter D. Lee, Paul Tafforeau, Claire Walsh, Mark P. Kuehnel, Detlef Schuppan, Marius M. Hoeper, Danny D. Jonigk, Maximilian Ackermann
Publicado en: American Journal of Respiratory and Critical Care Medicine, Edición 207, 2023, Página(s) 1105-1107, ISSN 1073-449X
Editor: American Thoracic Society
DOI: 10.1164/rccm.202212-2314le

The pulmonary vasculature in lethal COVID-19 and idiopathic pulmonary fibrosis at single-cell resolution

Autores: Laura P M H de Rooij, Lisa M Becker, Laure-Anne Teuwen, Bram Boeckx, Sander Jansen, Simon Feys, Stijn Verleden, Laurens Liesenborghs, Anna K Stalder, Sasha Libbrecht, Tina Van Buyten, Gino Philips, Abhishek Subramanian, Sébastien J Dumas, Elda Meta, Mila Borri, Liliana Sokol, Amélie Dendooven, Anh-Co K Truong, Jan Gunst, Pierre Van Mol, Jasmin D Haslbauer, Katerina Rohlenova, Thomas Menter, Robb
Publicado en: Cardiovascular Research, Edición 119, 2023, Página(s) 520-535, ISSN 0008-6363
Editor: Elsevier BV
DOI: 10.1093/cvr/cvac139

Quantitative analysis of airway obstruction in lymphangioleiomyomatosis

Autores: Stijn E. Verleden, Arno Vanstapel, Laurens De Sadeleer, Birgit Weynand, Matthieu Boone, Erik Verbeken, Davide Piloni, Dirk Van Raemdonck, Maximilian Ackermann, Danny D. Jonigk, Johny Verschakelen, Wim A. Wuyts
Publicado en: European Respiratory Journal, Edición 56, 2024, Página(s) 1901965, ISSN 0903-1936
Editor: European Respiratory Society
DOI: 10.1183/13993003.01965-2019

From Macroscopy to Ultrastructure: An Integrative Approach to Pulmonary Pathology

Autores: Stijn E. Verleden, Peter Braubach, Christopher Werlein, Edith Plucinski, Mark P. Kuhnel, Annemiek Snoeckx, Haroun El Addouli, Tobias Welte, Axel Haverich, Florian P. Laenger, Sabine Dettmer, Patrick Pauwels, Veronique Verplancke, Paul E. Van Schil, Therese Lapperre, Johanna M. Kwakkel-Van-Erp, Maximilian Ackermann, Jeroen M. H. Hendriks, Danny Jonigk
Publicado en: Frontiers in Medicine, Edición 9, 2022, ISSN 2296-858X
Editor: Frontiers
DOI: 10.3389/fmed.2022.859337

The Bronchial Circulation in COVID-19 Pneumonia

Autores: Maximilian Ackermann, Paul Tafforeau, Willi L. Wagner, Claire L. Walsh, Christopher Werlein, Mark P. Kühnel, Florian P. Länger, Catherine Disney, Andrew J. Bodey, Alexandre Bellier, Stijn E. Verleden, Peter D. Lee, Steven J. Mentzer, Danny D. Jonigk
Publicado en: American Journal of Respiratory and Critical Care Medicine, Edición 205, 2022, Página(s) 121-125, ISSN 1073-449X
Editor: American Thoracic Society
DOI: 10.1164/rccm.202103-0594im

Fibrotischer Lungenparenchymumbau nach Lungen- und Stammzelltransplantation

Autores: Christopher Werlein, Max Ackermann, Thia Leandra Hoffmann, Florian Laenger, Danny Jonigk
Publicado en: Der Pathologe, Edición 42, 2021, Página(s) 17-24, ISSN 0172-8113
Editor: Springer Verlag
DOI: 10.1007/s00292-020-00898-2

Morphological and molecular motifs of fibrosing pulmonary injury patterns

Autores: Danny Jonigk, Helge Stark, Peter Braubach, Lavinia Neubert, Hoen‐oh Shin, Nicole Izykowski, Tobias Welte, Sabina Janciauskiene, Gregor Warnecke, Axel Haverich, Mark Kuehnel, Florian Laenger
Publicado en: The Journal of Pathology: Clinical Research, Edición 5/4, 2019, Página(s) 256-271, ISSN 2056-4538
Editor: Wiley Online Library
DOI: 10.1002/cjp2.141

Morphomolecular motifs of pulmonary neoangiogenesis in interstitial lung diseases

Autores: Maximilian Ackermann, Helge Stark, Lavinia Neubert, Stephanie Schubert, Paul Borchert, Friedemann Linz, Willi L. Wagner, Wolfram Stiller, Mark Wielpütz, Anne Hoefer, Axel Haverich, Steven J. Mentzer, Harshit R. Shah, Tobias Welte, Mark Kuehnel, Danny Jonigk
Publicado en: European Respiratory Journal, 2019, Página(s) 1900933, ISSN 0903-1936
Editor: European Respiratory Society
DOI: 10.1183/13993003.00933-2019

Schädigungsmuster interstitieller Lungenerkrankungen

Autores: F. Länger, H. Stark, P. Braubach, M. Ackermann, K. Hussein, K. Teiken, L. Maegel, M. Kuehnel, D. Jonigk
Publicado en: Der Pathologe, Edición 39/S2, 2018, Página(s) 262-271, ISSN 0172-8113
Editor: Springer Verlag
DOI: 10.1007/s00292-018-0503-1

Lungentransplantation

Autores: J. Wohlschlaeger, F. Laenger, J. Gottlieb, T. Hager, A. Seidel, D. Jonigk
Publicado en: Der Pathologe, Edición 40/3, 2019, Página(s) 281-291, ISSN 0172-8113
Editor: Springer Verlag
DOI: 10.1007/s00292-019-0598-z

Basal-Like Cell-Conditioned Medium Exerts Anti-Fibrotic Effects In Vitro and In Vivo

Autores: Petra Khan, Kleanthis Fytianos, Sabrina Blumer, Julien Roux, Amiq Gazdhar, Spasenija Savic, Lars Knudsen, Danny Jonigk, Mark P. Kuehnel, Sofia Mykoniati, Michael Tamm, Thomas Geiser, Katrin E. Hostettler
Publicado en: Frontiers in Bioengineering and Biotechnology, Edición 10, 2022, ISSN 2296-4185
Editor: Frontiers
DOI: 10.3389/fbioe.2022.844119

Inflammation and vascular remodeling in COVID-19 hearts

Autores: Christopher Werlein, Maximilian Ackermann, Helge Stark, Harshit R. Shah, Alexandar Tzankov, Jasmin Dinonne Haslbauer, Saskia von Stillfried, Roman David Bülow, Ali El-Armouche, Stephan Kuenzel, Jan Lukas Robertus, Marius Reichardt, Axel Haverich, Anne Höfer, Lavinia Neubert, Edith Plucinski, Peter Braubach, Stijn Verleden, Tim Salditt, Nikolaus Marx, Tobias Welte, Johann Bauersachs, Hans-Heinric
Publicado en: Angiogenesis, Edición 26, 2023, Página(s) 233-248, ISSN 0969-6970
Editor: Kluwer Academic Publishers
DOI: 10.1007/s10456-022-09860-7

FDA-Approved Inhibitors of RTK/Raf Signaling Potently Impair Multiple Steps of In Vitro and Ex Vivo Influenza A Virus Infections

Autores: Robert Meineke, Sonja Stelz, Maximilian Busch, Christopher Werlein, Mark Kühnel, Danny Jonigk, Guus F. Rimmelzwaan, Husni Elbahesh
Publicado en: Viruses, Edición 14, 2024, Página(s) 2058, ISSN 1999-4915
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v14092058

Die aktualisierte S2k-Leitlinie zur Diagnostik der idiopathischen Lungenfibrose

Autores: Ludger Fink, Danny Jonigk
Publicado en: Der Pathologe, Edición 42, 2021, Página(s) 40-47, ISSN 0172-8113
Editor: Springer Verlag
DOI: 10.1007/s00292-020-00894-6

Multi-omic profiling of follicular lymphoma reveals changes in tissue architecture and enhanced stromal remodeling in high-risk patients

Autores: Andrea J. Radtke, Ekaterina Postovalova, Arina Varlamova, Alexander Bagaev, Maria Sorokina, Olga Kudryashova, Mark Meerson, Margarita Polyakova, Ilia Galkin, Viktor Svekolkin, Sergey Isaev, Daniil Wiebe, Anna Sharun, Alexander Sarachakov, Grigory Perelman, Yaroslav Lozinsky, Ziv Yaniv, Bradley C. Lowekamp, Emily Speranza, Li Yao, Stefania Pittaluga, Arthur L. Shaffer, Danny Jonigk, James D. Phelan
Publicado en: Cancer Cell, Edición 42, 2024, Página(s) 444-463.e10, ISSN 1535-6108
Editor: Cell Press
DOI: 10.1016/j.ccell.2024.02.001

Role of the COX2-PGE2 axis in S. pneumoniae-induced exacerbation of experimental fibrosis

Autores: Tina Bormann, Regina Maus, Jennifer Stolper, Danny Jonigk, Tobias Welte, Jack Gauldie, Martin Kolb, Ulrich A. Maus
Publicado en: American Journal of Physiology-Lung Cellular and Molecular Physiology, Edición 320, 2021, Página(s) L377-L392, ISSN 1040-0605
Editor: American Physiological Society
DOI: 10.1152/ajplung.00024.2020

Amyloid precursor protein as a fibrosis marker in infants with biliary atresia

Autores: Jan C. Kamp, Omid Madadi-Sanjani, Marie Uecker, Christopher Werlein, Lavinia Neubert, Joachim F. Kübler, Mikal Obed, Norman Junge, Tobias Welte, Jannik Ruwisch, Danny D. Jonigk, Jan Stolk, Gertrud Vieten, Sabina Janciauskiene
Publicado en: Pediatric Research, 2024, ISSN 0031-3998
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1038/s41390-024-03582-w

3D virtual pathohistology of lung tissue from Covid-19 patients based on phase contrast X-ray tomography

Autores: Marina Eckermann, Jasper Frohn, Marius Reichardt, Markus Osterhoff, Michael Sprung, Fabian Westermeier, Alexandar Tzankov, Christopher Werlein, Mark Kühnel, Danny Jonigk, Tim Salditt
Publicado en: eLife, Edición 9, 2023, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.60408

Comparative Analysis of Gene Expression in Fibroblastic Foci in Patients with Idiopathic Pulmonary Fibrosis and Pulmonary Sarcoidosis

Autores: Jan C. Kamp, Lavinia Neubert, Helge Stark, Jan B. Hinrichs, Caja Boekhoff, Allison D. Seidel, Fabio Ius, Axel Haverich, Jens Gottlieb, Tobias Welte, Peter Braubach, Florian Laenger, Marius M. Hoeper, Mark P. Kuehnel, Danny D. Jonigk
Publicado en: Cells, Edición 11, 2024, Página(s) 664, ISSN 2073-4409
Editor: MDPI
DOI: 10.3390/cells11040664

Dual Function of iPSC-Derived Pericyte-Like Cells in Vascularization and Fibrosis-Related Cardiac Tissue Remodeling In Vitro

Autores: Monika Szepes, Anna Melchert, Julia Dahlmann, Jan Hegermann, Christopher Werlein, Danny Jonigk, Axel Haverich, Ulrich Martin, Ruth Olmer, Ina Gruh
Publicado en: International Journal of Molecular Sciences, Edición 21, 2024, Página(s) 8947, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21238947

Pulmonary Fibroelastotic Remodelling Revisited

Autores: Peter Braubach, Christopher Werlein, Stijn E. Verleden, Isabell Maerzke, Jens Gottlieb, Gregor Warnecke, Sabine Dettmer, Florian Laenger, Danny Jonigk
Publicado en: Cells, Edición 10, 2024, Página(s) 1362, ISSN 2073-4409
Editor: MDPI
DOI: 10.3390/cells10061362

FDA-approved Abl/EGFR/PDGFR kinase inhibitors show potent efficacy against pandemic and seasonal influenza A virus infections of human lung explants

Autores: Robert Meineke, Sonja Stelz, Maximilian Busch, Christopher Werlein, Mark Kühnel, Danny Jonigk, Guus F. Rimmelzwaan, Husni Elbahesh
Publicado en: iScience, Edición 26, 2024, Página(s) 106309, ISSN 2589-0042
Editor: MDPI
DOI: 10.1016/j.isci.2023.106309

Reply to Bush et al. and to Persson

Autores: Maximilian Ackermann, Steven J. Mentzer, Danny D. Jonigk
Publicado en: American Journal of Respiratory and Critical Care Medicine, Edición 206, 2022, Página(s) 229-230, ISSN 1073-449X
Editor: American Thoracic Society
DOI: 10.1164/rccm.202201-0122le

A Morphomolecular Approach to Alveolar Capillary Dysplasia

Autores: Jan C. Kamp, Lavinia Neubert, Maximilian Ackermann, Helge Stark, Edith Plucinski, Harshit R. Shah, Sabina Janciauskiene, Anke K. Bergmann, Gunnar Schmidt, Tobias Welte, Axel Haverich, Christopher Werlein, Peter Braubach, Florian Laenger, Nicolaus Schwerk, Karen M. Olsson, Jan Fuge, Da-Hee Park, Jonas C. Schupp, Marius M. Hoeper, Mark P. Kuehnel, Danny D. Jonigk
Publicado en: The American Journal of Pathology, Edición 192, 2022, Página(s) 1110-1121, ISSN 0002-9440
Editor: American Society for Investigative Pathology
DOI: 10.1016/j.ajpath.2022.05.004

Synergistic inhibition of SARS-CoV-2 cell entry by otamixaban and covalent protease inhibitors: pre-clinical assessment of pharmacological and molecular properties

Autores: Tim Hempel, Katarina Elez, Nadine Krüger, Lluís Raich, Jonathan H. Shrimp, Olga Danov, Danny Jonigk, Armin Braun, Min Shen, Matthew D. Hall, Stefan Pöhlmann, Markus Hoffmann, Frank Noé
Publicado en: Chemical Science, Edición 12, 2024, Página(s) 12600-12609, ISSN 2041-6520
Editor: Royal Society of Chemistry
DOI: 10.1039/d1sc01494c

<scp>Interleukin‐17A</scp> and interleukin‐22 production by conventional and non‐conventional lymphocytes in three different end‐stage lung diseases

Autores: Melanie Albrecht, Olga Halle, Svenja Gaedcke, Sophia T Pallenberg, Julia Camargo Neumann, Marius Witt, Johanna Roediger, Marina Schumacher, Adan Chari Jirmo, Gregor Warnecke, Danny Jonigk, Peter Braubach, David DeLuca, Gesine Hansen, Anna‐Maria Dittrich
Publicado en: Clinical & Translational Immunology, Edición 11, 2023, ISSN 2050-0068
Editor: Wiley
DOI: 10.1002/cti2.1398

Multisystemic Cellular Tropism of SARS-CoV-2 in Autopsies of COVID-19 Patients

Autores: Dickson W. L. Wong, Barbara M. Klinkhammer, Sonja Djudjaj, Sophia Villwock, M. Cherelle Timm, Eva M. Buhl, Sophie Wucherpfennig, Claudio Cacchi, Till Braunschweig, Ruth Knüchel-Clarke, Danny Jonigk, Christopher Werlein, Roman D. Bülow, Edgar Dahl, Saskia von Stillfried, Peter Boor
Publicado en: Cells, Edición 10, 2024, Página(s) 1900, ISSN 2073-4409
Editor: MDPI
DOI: 10.3390/cells10081900

COVID-19: what the clinician should know about post-mortem findings

Autores: Danny Jonigk, Bruno Märkl, Julie Helms
Publicado en: Intensive Care Medicine, Edición 47, 2021, Página(s) 86-89, ISSN 0342-4642
Editor: Springer Verlag
DOI: 10.1007/s00134-020-06302-0

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

Autores: Maximilian Ackermann, Stijn E. Verleden, Mark Kuehnel, Axel Haverich, Tobias Welte, Florian Laenger, Arno Vanstapel, Christopher Werlein, Helge Stark, Alexandar Tzankov, William W. Li, Vincent W. Li, Steven J. Mentzer, Danny Jonigk
Publicado en: New England Journal of Medicine, Edición 383, 2020, Página(s) 120-128, ISSN 0028-4793
Editor: Massachusetts Medical Society
DOI: 10.1056/nejmoa2015432

IBEX: An open and extensible method for high content multiplex imaging of diverse tissues

Autores: Radtke, Andrea J.; Chu, Colin J.; Yaniv, Ziv; Yao, Li; Marr, James; Beuschel, Rebecca T.; Ichise, Hiroshi; Gola, Anita; Kabat, Juraj; Lowekamp, Bradley; Speranza, Emily; Croteau, Joshua; Thakur, Nishant; Jonigk, Danny; Davis, Jeremy; Hernandez, Jonathan M.; Germain, Ronald N.
Publicado en: Edición 2, 2021
Editor: Cornell University
DOI: 10.48550/arxiv.2107.11364

A multiscale X-ray phase-contrast tomography dataset of whole human left lung

Autores: R. Patrick Xian, Claire L. Walsh, Stijn E. Verleden, Willi L. Wagner, Alexandre Bellier, Sebastian Marussi, Maximilian Ackermann, Danny D. Jonigk, Joseph Jacob, Peter D. Lee, Paul Tafforeau
Publicado en: 2022
Editor: Cold Spring Harbor Laboratory
DOI: 10.1101/2021.11.20.469361

3D virtual Histopathology of Cardiac Tissue from Covid-19 Patients based on Phase-Contrast X-ray Tomography

Autores: Marius Reichardt, Patrick Møller Jensen, Vedrana Andersen Dahl, Anders Bjorholm Dahl, Maximilian Ackermann, Harshit Shah, Florian Länger, Christopher Werlein, Mark Kühnel, Danny Jonigk, Tim Salditt
Publicado en: 2022
Editor: Cold Spring Harbour
DOI: 10.1101/2021.09.16.460594

Deep Learning for 3D Vascular Segmentation in Phase Contrast Tomography

Autores: Ekin Yagis, Shahab Aslani, Yashvardhan Jain, Yang Zhou, Shahrokh Rahmani, Joseph Brunet, Alexandre Bellier, Christopher Werlein, Maximilian Ackermann, Danny Jonigk, Paul Tafforeau, Claire Walsh, Peter D Lee
Publicado en: 2024
Editor: Springer Science and Business Media LLC
DOI: 10.21203/rs.3.rs-4613439/v1

Multiscale three-dimensional imaging of intact human organs down to the cellular scale using hierarchical phase-contrast tomography

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