Descripción del proyecto
Dispositivo móvil para el diagnóstico de enfermedades porcinas
Las eficacia de los medicamentos y las vacunas ha reducido la carga directa que representan las enfermedades del ganado en los países desarrollados. Sin embargo, los sistemas modernos de producción animal, superpoblados, siguen siendo vulnerables a agentes infecciosos y enfermedades que pueden tener graves consecuencias para la sanidad animal y la ganadería. A fin de hacer frente a la amenaza de brotes de enfermedades, el proyecto SWINOSTICS, financiado con fondos europeos, propone el desarrollo de una herramienta de diagnóstico «in situ» que proporcione resultados para seis enfermedades porcinas diferentes asociadas a virus en cuestión de minutos. El dispositivo de biodetección basado en nanotecnología utiliza anticuerpos para evaluar rápidamente varias muestras a la vez, superando el laborioso proceso de análisis convencional. La alta sensibilidad y especificidad de la herramienta SWINOSTICS permitirá tomar decisiones a escala local para prevenir la propagación de enfermedades.
Objetivo
The increased population density in modern animal production systems has made them vulnerable to various transboundary infectious agents & diseases. During the last decades in the developed world, a reduction in the direct burden of livestock diseases has been observed, because of more effective drugs & vaccines. However, the total impact may actually be increasing, because in a highly-interconnected world, the effects of diseases extend far beyond animal sickness & mortality. Therefore, early diagnosis and establishment of reliable countermeasures to infectious disease outbreaks is essential to limit severe biophysical and socio-economic consequences.
To date, the time between initial disease outbreak and laboratory confirmation of the etiologic infectious agent can be up to several weeks. Reliable & simple diagnostic testing directly on site would enable rapid local decision making, which is crucial to prevent further spreading of the disease.
Silicon-based Photonic Integrated Circuits (PIC) have been demonstrated as a powerful platform for biosensing systems. In combination with integrated monoclonal antibodies, they can provide portable multiplex detection of proteins with sensitivity & specificity previously not realized. SWINOSTICS addresses the sector needs, by developing a novel field diagnostic device, based on advanced, proven, bio-sensing technologies to tackle viruses causing epidemics in swine farms and leading to relevant economic damages, complying to the objectives of the STAR-IDAZ. The diagnostic device will allow threat assessment at the farm level, with the analytical quality of commercial laboratories. The device will be developed for a panel of 6 important swine diseases. The device will be portable & will provide results in 10 minutes for 5 samples simultaneously, making it highly suitable for field use. It is based on 3 lab-verified concepts: a) PIC technology, b) Label-free optical detection, c) patented nano-deposition technology.
Ámbito científico
- natural sciencesbiological sciencesbiochemistrybiomoleculesnucleic acids
- medical and health scienceshealth sciencesinfectious diseasesRNA virusesinfluenza
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccines
- engineering and technologymedical engineeringmedical laboratory technologydiagnostic technologies
- agricultural sciencesanimal and dairy sciencedomestic animalsanimal husbandry
Palabras clave
Programa(s)
Convocatoria de propuestas
Consulte otros proyectos de esta convocatoriaConvocatoria de subcontratación
H2020-SFS-2017-1
Régimen de financiación
IA - Innovation actionCoordinador
1060 Lefkosia
Chipre
Organización definida por ella misma como pequeña y mediana empresa (pyme) en el momento de la firma del acuerdo de subvención.