Chronic Systemic Inflammation: Functional organ cross-talk in inflammatory disease and cancer

Dual therapeutic targeting of MYC and JUNB transcriptional programs for enhanced anti-myeloma activity

Autorzy: Judith Lind, Osman Aksoy, Michaela Prchal-Murphy, Fengjuan Fan, Mariateresa Fulciniti, Dagmar Stoiber, Latifa Bakiri, Erwin F. Wagner, Elisabeth Zwickl-Traxler, Martin Sattler, Karoline Kollmann, Sonia Vallet, Klaus Podar
Opublikowane w: Blood Cancer Journal, Numer 14, 2024, Strona(/y) 138, ISSN 2044-5385
Wydawca: Nature Publishing Group
DOI: 10.1038/s41408-024-01117-4

Early Neutrophilia Marked by Aerobic Glycolysis Sustains Host Metabolism and Delays Cancer Cachexia

Autorzy: Michele Petruzzelli, Miriam Ferrer, Martijn J. Schuijs, Sam O. Kleeman, Nicholas Mourikis, Zoe Hall, David Perera, Shwethaa Raghunathan, Michele Vacca, Edoardo Gaude, Michael J. Lukey, Duncan I. Jodrell, Christian Frezza, Erwin F. Wagner, Ashok R. Venkitaraman, Timotheus Y. F. Halim,Tobias Janowitz
Opublikowane w: Cancers (Basel), Numer Feb 15;14(4), 2022, Strona(/y) 963, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14040963

Sequestosome 1/p62 enhances chronic skin inflammation

Autorzy: Supawadee Sukseree, Latifa Bakiri, Marta Palomo-Irigoyen, Özge Uluçkan, Peter Petzelbauer, Erwin F. Wagner
Opublikowane w: Journal of Allergy and Clinical Immunology, Numer 147/6, 2021, Strona(/y) 2386-2393.e4, ISSN 0091-6749
Wydawca: Mosby Inc.
DOI: 10.1016/j.jaci.2021.02.028

Topical application of an amygdalin analogue reduces inflammation and keratinocyte proliferation in a psoriasis mouse model

Autorzy: Nuria Gago‐López, Carmen Lagunas Arnal, Juan J. Perez, Erwin F. Wagner
Opublikowane w: Experimental Dermatology, 2021, ISSN 0906-6705
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/exd.14390

The AP-1 transcription factors c-Jun and JunB are essential for CD8α conventional dendritic cell identity

Autorzy: Philipp Novoszel, Barbara Drobits, Martin Holcmann, Cristiano De Sa Fernandes, Roland Tschismarov, Sophia Derdak, Thomas Decker, Erwin F. Wagner, Maria Sibilia
Opublikowane w: Cell Death & Differentiation, 2021, ISSN 1350-9047
Wydawca: Nature Publishing Group
DOI: 10.1038/s41418-021-00765-4

TPL-2 Inhibits IFN-β Expression via an ERK1/2-TCF-FOS Axis in TLR4-Stimulated Macrophages

Autorzy: Louise Blair, Michael J. Pattison, Probir Chakravarty, Stamatia Papoutsopoulou, Latifa Bakiri, Erwin F. Wagner, Stephen Smale, Steven C. Ley
Opublikowane w: J Immunol, Numer Feb 15; 208 (4), 2022, Strona(/y) 941–954, ISSN 0022-1767
Wydawca: American Association of Immunologists
DOI: 10.4049/jimmunol.2100213

Wnt signaling and Loxl2 promote aggressive osteosarcoma

Autorzy: Kazuhiko Matsuoka, Latifa Bakiri, Lena I. Wolff, Markus Linder, Amanda Mikels-Vigdal, Ana Patiño-García, Fernando Lecanda, Christine Hartmann, Maria Sibilia, Erwin F. Wagner
Opublikowane w: Cell Research, Numer 30/10, 2020, Strona(/y) 885-901, ISSN 1001-0602
Wydawca: Kexue Chubaneshe/Science Press
DOI: 10.1038/s41422-020-0370-1

Psoriatic skin inflammation is promoted by c‐Jun/AP‐1‐dependent CCL2 and IL‐23 expression in dendritic cells

Autorzy: Philipp Novoszel, Martin Holcmann, Gabriel Stulnig, Cristiano De Sa Fernandes, Victoria Zyulina, Izabela Borek, Markus Linder, Alexandra Bogusch, Barbara Drobits, Thomas Bauer, Carmen Tam‐Amersdorfer, Patrick M Brunner, Georg Stary, Latifa Bakiri, Erwin F Wagner, Herbert Strobl, Maria Sibilia
Opublikowane w: EMBO Molecular Medicine, Numer 13/4, 2021, ISSN 1757-4676
Wydawca: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.202012409

Keratinocyte-derived S100A9 modulates neutrophil infiltration and affects psoriasis-like skin and joint disease

Autorzy: Liliana F Mellor; Nuria Gago-Lopez; Latifa Bakiri; Felix N Schmidt; Björn Busse; Simon Rauber; Maria Jimenez; Diego Megías; Sergio Oterino-Sogo; Ricardo Sanchez-Prieto; Sergei Grivennikov; Xinzhu Pu; Julia Oxford; Andreas Ramming; Georg Schett; Erwin F Wagner
Opublikowane w: Ann Rheum Dis, Numer 00034967, 2022, Strona(/y) 1400-1408, ISSN 0003-4967
Wydawca: BMJ Publishing Group
DOI: 10.1136/annrheumdis-2022-222229

Role of bulge epidermal stem cells and TSLP signaling in psoriasis

Autorzy: Nuria Gago‐Lopez, Liliana F Mellor, Diego Megías, Guillermo Martín‐Serrano, Ander Izeta, Francisco Jimenez, Erwin F Wagner
Opublikowane w: EMBO Molecular Medicine, Numer 11/11, 2019, ISSN 1757-4676
Wydawca: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.201910697

EGFR controls bone development by negatively regulating mTOR-signaling during osteoblast differentiation

Autorzy: Markus Linder, Manfred Hecking, Elisabeth Glitzner, Karin Zwerina, Martin Holcmann, Latifa Bakiri, Maria Grazia Ruocco, Jan Tuckermann, Georg Schett, Erwin F. Wagner, Maria Sibilia
Opublikowane w: Cell Death & Differentiation, Numer 25/6, 2018, Strona(/y) 1094-1106, ISSN 1350-9047
Wydawca: Nature Publishing Group
DOI: 10.1038/s41418-017-0054-7

Cutaneous Immune Cell-Microbiota Interactions Are Controlled by Epidermal JunB/AP-1

Autorzy: Özge Uluçkan, Maria Jiménez, Ben Roediger, Jakob Schnabl, Lucía T. Díez-Córdova, Kevin Troulé, Wolfgang Weninger, Erwin F. Wagner
Opublikowane w: Cell Reports, Numer 29/4, 2019, Strona(/y) 844-859.e3, ISSN 2211-1247
Wydawca: Cell Press
DOI: 10.1016/j.celrep.2019.09.042

Fra-2 Expression in Osteoblasts Regulates Systemic Inflammation and Lung Injury through Osteopontin

Autorzy: Yubin Luo, Bettina Grötsch, Nicole Hannemann, Maria Jimenez, Natacha Ipseiz, Ozge Uluckan, Nengyu Lin, Georg Schett, Erwin F. Wagner, Aline Bozec
Opublikowane w: Molecular and Cellular Biology, Numer 38/22, 2018, ISSN 0270-7306
Wydawca: American Society for Microbiology
DOI: 10.1128/mcb.00022-18

Fra-2–expressing macrophages promote lung fibrosis

Autorzy: Alvaro C. Ucero, Latifa Bakiri, Ben Roediger, Masakatsu Suzuki, Maria Jimenez, Pratyusha Mandal, Paola Braghetta, Paolo Bonaldo, Luis Paz-Ares, Coral Fustero-Torre, Pilar Ximenez-Embun, Ana Isabel Hernandez, Diego Megias, Erwin F. Wagner
Opublikowane w: Journal of Clinical Investigation, Numer 129/8, 2019, Strona(/y) 3293-3309, ISSN 0021-9738
Wydawca: American Society for Clinical Investigation
DOI: 10.1172/jci125366

EGFR is required for FOS‐dependent bone tumor development via RSK2/CREB signaling

Autorzy: Markus Linder, Elisabeth Glitzner, Sriram Srivatsa, Latifa Bakiri, Kazuhiko Matsuoka, Parastoo Shahrouzi, Monika Dumanic, Philipp Novoszel, Thomas Mohr, Oliver Langer, Thomas Wanek, Markus Mitterhauser, Erwin F Wagner, Maria Sibilia
Opublikowane w: EMBO Molecular Medicine, Numer 10/11, 2018, ISSN 1757-4676
Wydawca: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.201809408

JunB is a key regulator of multiple myeloma bone marrow angiogenesis

Autorzy: Fengjuan Fan, Stefano Malvestiti, Sonia Vallet, Judith Lind, Jose Manuel Garcia-Manteiga, Eugenio Morelli, Qinyue Jiang, Anja Seckinger, Dirk Hose, Hartmut Goldschmidt, Andreas Stadlbauer, Chunyan Sun, Heng Mei, Martin Pecherstorfer, Latifa Bakiri, Erwin F. Wagner, Giovanni Tonon, Martin Sattler, Yu Hu, Pierfrancesco Tassone, Dirk Jaeger, Klaus Podar
Opublikowane w: Leukemia, 2021, ISSN 0887-6924
Wydawca: Nature Publishing Group
DOI: 10.1038/s41375-021-01271-9

Targeting AP-1 transcription factors by CRISPR in the prostate

Autorzy: Maria Riedel, Huiqiang Cai, Iben C Stoltze, Mikkel H Vendelbo, Erwin F Wagner, Latifa Bakiri, Martin K Thomsen
Opublikowane w: Oncotarget, Numer Sep 14;12(19), 2021, Strona(/y) 1956-1961, ISSN 1949-2553
Wydawca: Impact Journals
DOI: 10.18632/oncotarget.27997

In vivo CRISPR inactivation of Fos promotes prostate cancer progression by altering the associated AP-1 subunit Jun

Autorzy: Maria Riedel, Martin F. Berthelsen, Huiqiang Cai, Jakob Haldrup, Michael Borre, Søren R. Paludan, Henrik Hager, Mikkel H. Vendelbo, Erwin F. Wagner, Latifa Bakiri, Martin K. Thomsen
Opublikowane w: Oncogene, Numer 40/13, 2021, Strona(/y) 2437-2447, ISSN 0950-9232
Wydawca: Nature Publishing Group
DOI: 10.1038/s41388-021-01724-6

Interleukin-6 initiates muscle- and adipose tissue wasting in a novel C57BL/6 model of cancer-associated cachexia

Autorzy: Isabella Pototschnig, Ursula Feiler, Clemens Diwoky, Paul W. Vesely, Thomas Rauchenwald, Margret Paar, Latifa Bakiri, Laura Pajed, Peter Hofer, Karl Kashofer, Nyamdelger Sukhbaatar, Gabriele Schoiswohl, Thomas Weichhart, Gerald Hoefler, Christoph Bock, Martin Pichler, Erwin F. Wagner, Rudolf Zechner, Martina Schweiger
Opublikowane w: Journal of Cachexia, Sarcopenia and Muscle, Numer Nov 9, online ahead of print, 2022, ISSN 2190-5991
Wydawca: Springer Verlag
DOI: 10.1002/jcsm.13109

Liver cancer development driven by the AP-1/c-Jun~Fra-2 dimer through c-Myc.

Autorzy: Latifa Bakiri, Sebastian C Hasenfuss, Ana Guío-Carrión, Martin K Thomsen, Peter Hasselblatt, Erwin F Wagner.
Opublikowane w: Proc Natl Acad Sci U S A, Numer Apr 30;121(18) - Epub, 2024, Strona(/y) e2404188121 (Epub), ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.2404188121

Metabolic rewiring controlled by c-Fos governs cartilage integrity in osteoarthritis

Autorzy: Kazuhiko Matsuoka, Latifa Bakiri, Martin Bilban, Stefan Toegel, Arvand Haschemi, Hao Yuan, Maria Kasper, Reinhard Windhager, Erwin F Wagner
Opublikowane w: Ann Rheum Dis, Numer Jun 21, 2023, Strona(/y) ard-2023-224002, ISSN 0003-4967
Wydawca: BMJ Publishing Group
DOI: 10.1136/ard-2023-224002

An immune-sympathetic neuron communication axis guides adipose tissue browning in cancer-associated cachexia

Autorzy: Hao Xie, Christoph Heier, Xia Meng, Latifa Bakiri, Isabella Pototschnig, Zhiyuan Tang, Silvia Schauer, Vanessa J. Baumgartner, Gernot F. Grabner, Gernot Schabbauer, Heimo Wolinski, Graham R. Robertson, Gerald Hoefler, Wenwen Zeng, Erwin F. Wagner, Martina Schweiger, Rudolf Zechner
Opublikowane w: Proc Natl Acad Sci U S A, Numer Mar 1; 119(9), 2022, Strona(/y) e2112840119, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.2112840119

The role of S100A8, S100A9 and Calprotectin in skin inflammation

Autorzy: Marta Palomo Irigoyen, Latifa Bakiri, Erwin F Wagner
Opublikowane w: FEBS Open Bio, Numer 12 (Suppl. S1), 2022, Strona(/y) 2–66, ISSN 2211-5463
Wydawca: John Wiley & Sons on behalf of the Federation of European Biochemical Societies
DOI: 10.1002/2211-5463.13442

Dissecting the progression of cardiac dysfunction in tumor-bearing mice

Autorzy: Dostal, LP Szabo, C Aioanei, D Abraham, K Zins, Latifa Bakiri, E Wagner, BK Podesser, A Kiss
Opublikowane w: Cardiovascular Research, Numer Vol 118, Supplement 1, 2022, Strona(/y) cvac066.247, ISSN 1755-3245
Wydawca: Oxford Academic
DOI: 10.1093/cvr/cvac066.247

p62, a pro-inflammatory protein in atopic dermatitis has a protective role in a mouse model of psoriasis

Autorzy: Kamil Mieczkowski, Latifa Bakiri, Erwin F. Wagner
Opublikowane w: Journal of Investigative Dermatology, Numer 143 (11), Supplement, 2023, Strona(/y) S355, ISSN 0022-202X
Wydawca: Elsevier
DOI: 10.1016/j.jid.2023.09.143

Cell-specific immune-modulatory functions of S100A8/A9 in Atopic Dermatitis

Autorzy: Marta Palomo Irigoyen, Tim Hendrikx, Latifa Bakiri, Silvia Hayer, Johanna Schaffenrath, Philipp Starkl, Silvia Knapp, Erwin F. Wagner
Opublikowane w: Journal of Investigative Dermatology, Numer 143 (11), Supplement, 2023, Strona(/y) Page S356, ISSN 0022-202X
Wydawca: Elsevier
DOI: 10.1016/j.jid.2023.09.147

Dissecting the progression of cardiac dysfunction in tumor-bearing mice

Autorzy: C Dostal, LP Szabo, C Aioanei, D Abraham, K Zins, Latifa Bakiri, Erwin F Wagner, BK Podesser, Atilla Kiss.
Opublikowane w: The Wiener klinische Wochenschrift, Numer 134 (Suppl 2), 2022, Strona(/y) 77–210
Wydawca: Springer-Verlag Wien
DOI: 10.1007/s00508-022-02035-w

Elucidating the molecular link between psoriasis and skin cancer

Autorzy: Panagiota Tsokkou, Martin Holcmann, Kamil Mieczkowski, Latifa Bakiri, Maria Sibilia, Erwin F. Wagner.
Opublikowane w: Journal of Investigative Dermatology, Numer 143 (11), Supplement, 2023, Strona(/y) S350, ISSN 0022-202X
Wydawca: Elsevier
DOI: 10.1016/j.jid.2023.09.111

Skin deep and beyond: Function of Calprotectin (S100A8/A9)

Autorzy: Marta Palomo Irigoyen, Latifa Bakiri, Johanna Schaffenrath, Silvia Hayer, Philip Starkl, Silvia Knapp, Erwin F. Wagner.
Opublikowane w: Journal of Investigative Dermatology, Numer 142 (12), Supplement, 2022, Strona(/y) S242, ISSN 0022-202X
Wydawca: Elsevier
DOI: 10.1016/j.jid.2022.09.372

How does inflammation spread through the body?

Autorzy: Latifa Bakiri, Erwin F Wagner
Opublikowane w: EU Research, Numer Spring issue, vol. (34), 2023, Strona(/y) 17 - 19, ISSN 2752-4736
Wydawca: Blazon Publishing & Media Limited
DOI: 10.56181/fhju5543

Mechanismus der chronischen Entzündung bei atopischer Dermatitis

Autorzy: Supawadee Sukseree, Erwin F. Wagner
Opublikowane w: SPECTRUM Dermatologie, Numer SD 04|2021, Nov 18, 2021, ISSN 2223-0661
Wydawca: MedMedia Verlag und Mediaservice GmbH, Vienna

Open Thy Lattice Osteoclast, Resorb me!

Autorzy: Latifa Bakiri
Opublikowane w: J Cell Biol, Numer Volume 222, Numer 4,, 2023, Strona(/y) e202302033, ISSN 0021-9525
Wydawca: Rockefeller University Press
DOI: 10.1083/jcb.202302033

Mechanism of chronic inflammation in psoriasis-like skin and joint disease

Autorzy: Latifa Bakiri, Georg Schett , Erwin F Wagner
Opublikowane w: SPECTRUM Dermatologie, Numer SD 04|2022, Nov 24, 2022, Strona(/y) 94-95, ISSN 2223-0661
Wydawca: MedMedia Verlag und Mediaservice GmbH, Vienna

Novel therapeutic approaches for malignant bone cancer

Autorzy: Kazuhiko Matsuoka, Latifa Bakiri, Erwin F Wagner
Opublikowane w: SPECTRUM Onkologie, Numer SO 02|2021, April 15, 2021, ISSN 2223-0661
Wydawca: MedMedia Verlag

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