Deliverables
Compilation of publications, communications, press release and media coverage Contributors: All
Implement ORTHOUNION project on the dedicated website and establish a secured collaborative platformCollaborative plataform for ORTHOUNION project
Protocol and outcome analysis
Results and conclusions, ORTHOUNION clinical trialDescription and analysis of data according with the clinical protocol Contributors SERMAS 2 UULM 4 CHUT 7 IOR 8
Report on potency assay enabling the detection of highly osteogenic MSC preparationExperimental protocols and results
Report on the results of the cost-effectiveness analysis and cost-utility analysis of BM MSC therapy in long bone union delay (both intra clinical trial length and extra clinical trial at longer time horizon)Costeffectiveness and costutility outcome analysisContributors UULM 4 IOR 8 UAM 1
Intermediate list of publications, communications, press release and media coverageCompilation of divulgation publications, communications, press release and media coverage
Report on a potential model for industrial production of BM-MSC for bone regeneration that would be adequate for wide access to patients in medical practice at an affordable cost.Document suggesting a potential model for industrial production of BMMSC for bone regeneration that would be adequate for wide access to patients in medical practice at an affordable cost Contributors SERMAS 2 UULM 4 IOR 8 POLICLINICO 10UNIMORE 9
Report on the impact of MSCs on chemoattraction and differentiation of these cells by in vitro co-culture studies and by in vivo approaches in ectopic and orthotopic transplantationExperimental protocols and results
Report on time course of biochemical markers of bone turnover in patients with long-bone non unions after treatmentProtocol and outcome analysis
Completed recruitment, ORTHOUNION clinical trialReport including the real dates of patients recriutment per country Contributors SERMAS 2 UULM 4 CHUT 7 IOR 8
Report and publication of Consensus conference on non-unions treatment in EuropeResults of the consensus conference on nonunions treatment in Europe Contributors All
Publications
Author(s):
Enrique Gómez-Barrena, Norma G. Padilla-Eguiluz, Philippe Rosset
Published in:
EFORT Open Reviews, Issue 5/10, 2020, Page(s) 574-583, ISSN 2396-7544
Publisher:
EFORT
DOI:
10.1302/2058-5241.5.190062
Author(s):
Elisabetta Manuela Foppiani, Olivia Candini, Ilenia Mastrolia, Alba Murgia, Giulia Grisendi, Anna Valeria Samarelli, Giulia Boscaini, Lucrezia Pacchioni, Massimo Pinelli, Giorgio De Santis, Edwin M. Horwitz, Elena Veronesi, Massimo Dominici
Published in:
Stem Cell Research & Therapy, Issue 10/1, 2019, ISSN 1757-6512
Publisher:
BioMed Central
DOI:
10.1186/s13287-019-1200-6
Author(s):
Meike Dahlhaus, Julian Roos, Daniel Engel, Daniel Tews, Daniel Halbgebauer, Jan-Bernd Funcke, Sophie Kiener, Patrick J. Schuler, Johannes Döscher, Thomas K. Hoffmann, Julia Zinngrebe, Markus Rojewski, Hubert Schrezenmeier, Klaus-Michael Debatin, Martin Wabitsch, Pamela Fischer-Posovszky
Published in:
International Journal of Molecular Sciences, Issue 21/21, 2020, Page(s) 7907, ISSN 1422-0067
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/ijms21217907
Author(s):
Enrique Gómez-Barrena, Norma G. Padilla-Eguiluz, Eduardo García-Rey, Pablo Hernández-Esteban, José Cordero-Ampuero, Juan C. Rubio-Suárez
Published in:
Injury, Issue 51, 2020, Page(s) S55-S62, ISSN 0020-1383
Publisher:
Elsevier BV
DOI:
10.1016/j.injury.2020.02.030
Author(s):
Luciano Vidal, Carina Kampleitner, Meadhbh Á. Brennan, Alain Hoornaert, Pierre Layrolle
Published in:
Frontiers in Bioengineering and Biotechnology, Issue 8, 2020, ISSN 2296-4185
Publisher:
Creative Commons Attribution License
DOI:
10.3389/fbioe.2020.00061
Author(s):
Luciano Vidal, Carina Kampleitner, Stéphanie Krissian, Meadhbh Á Brennan, Oskar Hoffmann, Yago Raymond, Yassine Maazouz, Maria-Pau Ginebra, Philippe Rosset, Pierre Layrolle
Published in:
Scientific Reports, Issue 10/1, 2020, ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/s41598-020-63742-w
Author(s):
Paul Humbert, Meadhbh Á. Brennan, Julien De Lima, Régis Brion, Annie Adrait, Céline Charrier, Bénédicte Brulin, Valérie Trichet, Yohann Couté, Frédéric Blanchard, Pierre Layrolle
Published in:
Scientific Reports, Issue 11/1, 2021, ISSN 2045-2322
Publisher:
Nature Publishing Group
DOI:
10.1038/s41598-021-91258-4
Author(s):
Mariele Viganò, Rosaria Giordano, Lorenza Lazzari
Published in:
Regenerative Medicine, Issue 12/7, 2017, Page(s) 803-813, ISSN 1746-0751
Publisher:
Future Medicine Ltd.
DOI:
10.2217/rme-2017-0051
Author(s):
Enrique Gómez-Barrena, Norma G. Padilla-Eguiluz, Cristina Avendaño-Solá, Concepción Payares-Herrera, Ana Velasco-Iglesias, Ferran Torres, Philippe Rosset, Florian Gebhard, Nicola Baldini, Juan C. Rubio-Suarez, Eduardo García-Rey, José Cordero-Ampuero, Javier Vaquero-Martin, Francisco Chana, Fernando Marco, Javier García-Coiradas, Pedro Caba-Dessoux, Pablo de la Cuadra, Philippe Hernigou, Ch
Published in:
Stem Cells International, Issue 2018, 2018, Page(s) 1-13, ISSN 1687-966X
Publisher:
Stem Cells International
DOI:
10.1155/2018/6025918
Author(s):
Cyril d’Arros, Thierry Rouillon, Joelle Veziers, Olivier Malard, Pascal Borget, Guy Daculsi
Published in:
Frontiers in Bioengineering and Biotechnology, Issue 7, 2020, ISSN 2296-4185
Publisher:
Frontiers Media S.A.
DOI:
10.3389/fbioe.2019.00462
Author(s):
Elisa Maria Amann, Alexander Groß, Markus Thomas Rojewski, Hans Armin Kestler, Miriam Kalbitz, Rolf Erwin Brenner, Markus Huber-Lang, Hubert Schrezenmeier
Published in:
PLOS ONE, Issue 14/5, 2019, Page(s) e0216862, ISSN 1932-6203
Publisher:
Public Library of Science
DOI:
10.1371/journal.pone.0216862
Author(s):
Ilenia Mastrolia, Elisabetta Manuela Foppiani, Alba Murgia, Olivia Candini, Anna Valeria Samarelli, Giulia Grisendi, Elena Veronesi, Edwin M. Horwitz, Massimo Dominici
Published in:
STEM CELLS Translational Medicine, Issue 8/11, 2019, Page(s) 1135-1148, ISSN 2157-6564
Publisher:
AlphaMed Press
DOI:
10.1002/sctm.19-0044
Author(s):
Alessandro Cherubini, Mario Barilani, Riccardo L Rossi, Murtadhah M K Jalal, Francesco Rusconi, Giuseppe Buono, Enrico Ragni, Giovanna Cantarella, Hamish A R W Simpson, Bruno Péault, Lorenza Lazzari
Published in:
Nucleic Acids Research, Issue Nucleic Acids Research, Volume 47, Issue 10, 04 June 2019, 2019, Page(s) 5325–5340, ISSN 0305-1048
Publisher:
Oxford University Press
DOI:
10.1093/nar/gkz199
Author(s):
Paul Humbert, Meadhbh Á. Brennan, Noel Davison, Philippe Rosset, Valérie Trichet, Frédéric Blanchard, Pierre Layrolle
Published in:
Frontiers in Immunology, Issue 10, 2019, ISSN 1664-3224
Publisher:
Frontiers in Immunology
DOI:
10.3389/fimmu.2019.00663
Author(s):
Michela Salvadori, Nicola Cesari, Alba Murgia, Paola Puccini, Benedetta Riccardi, Massimo Dominici
Published in:
Molecular Therapy - Methods & Clinical Development, Issue 14, 2019, Page(s) 1-15, ISSN 2329-0501
Publisher:
CellPress
DOI:
10.1016/j.omtm.2019.05.004
Author(s):
Mariele Viganò, Silvia Budelli, Cristiana Lavazza, Tiziana Montemurro, Elisa Montelatici, Stefania de Cesare, Lorenza Lazzari, Anna Rosa Orlandi, Giovanna Lunghi, Rosaria Giordano
Published in:
Stem Cells International, Issue 2018, 2018, Page(s) 1-16, ISSN 1687-966X
Publisher:
Hindawi
DOI:
10.1155/2018/3038565
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