Veterinary Biocontained facility Network for excellence in animal infectiology research and experimentation

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Training material for specific critical positions in animal high containment facilities forwarded to WP5

Quantity of access provided over the duration of the project to viruses and virus-related reagents

Draft prototype of structure and mode of operation for the future of VetBioNet

Quantity of access provided over the duration of the project to animal facility

Quantity of access provided over the duration of the project to INRA infrastructures

Quantity of access provided over the duration of the project to RI Containment laboratories

Ethics Committee Best Practice Guidance

Optimised pathogenesis and immunity models in genetic context for BSL3 pathogens

ERG Agreement drafted for Partners willing to commit themselves after the end of the EU funding

Guidance on implementation of the 3Rs and EU Animal Experimentation Directive

Process guidelines for designing and upgrading BSL3/3+facilities for farmed animal species including design and assessment

Quantity of access provided over the duration of the project to INIA-BSL3-CISA

Development of alternative ELISAs for fish disease diagnostics and surveillance

Quantity of access provided over the duration of the project to ANSES-Ploufragran Plouzané

Quantity of access provided over the duration of the project to TPI-ISO10&11

Guidelines of minimum requirements and criteria for training provision and competency assessment

Novel avian/mammalian host models for airborne transmission and susceptibility

Draft plan outlining strategies for VetBioNet sustainability

Quantity of access provided over the duration of the project to APHA infrastructures

Quantity of access provided over the duration of the project to BSL3 lab & animal facility

Report on best practice for facility management, including emergency response and planning

Viral population/quasispecies analysis by NGS and analysis pipelines

Pulmonar microbiome effects related to porcine influenza infections

Updated guidelines for best practice and procedure exchange of aquatic animal infection facilities

Development of a differential serological assay to separate RHDV infection from RHDV2

Quantity of access provided over the duration of the project to MRI

Quantity of access provided over the duration of the project to BSL3/2 laboratories

Quantity of access provided over the duration of the project to IZSVe

Quantity of access provided over the duration of the project to Animal and BSL3 laboratories facilities

Quantity of access provided over the duration of the project to CVI

Position paper for policy makers on the biosafety of alkaline hydrolysis (biodigesters) as an alternative destruction technique to incineration based on the practical experience gained in the sector in Europe

Quantity of access provided over the duration of the project to ANSES-Nancy

Quantity of access provided over the duration of the project to AU-ANIS

Quantity of access provided over the duration of the project to EMC

Biorisk management programme for facilities handling large animals to achieve CWA 15793 standard

Quantity of access provided over the duration of the project to high-end molecular typing and immunological technologies

Novel reservoir host infection models for BSL3 zoonotic pathogens

Application of newly developed high throughput transcriptomic analytical tools NanoString and Fluidigm to livestock to examine the response to BSL3 pathogens

Quantity of access provided over the duration of the project to PIEWT-MFB

Report on the ethics of high containment (BSL3/BSL3+) animal infectious disease research

List of samples available from collections and procedure for the generation of samples on-demand published on the website

Open science and Stakeholder Engagement Strategy Report

Guidelines for best practice in Post-Mortem facilities

List of Activities of Interest to be maintained after the EU funding period, inventory of potential external funding sources and identification of Partner legal requirements

Improved fish model for relevant pathogens in aquiculture

Quantity of access provided over the duration of the project to FLI3

Validation of integrated telemetry and behavioural monitoring

Enhanced temporal and organ-specific readouts of infectious diseases models including more refined criteria for the application of humane end points in order to minimize animal welfare impact

Effective decontamination of biological specimens infected with class 3 viruses for further study outside containment

Utilisation of NGS based tools to explore the T and B cell repertoires in domestic livestock before and after infection with BSL3 pathogen

Development and validation of molecular tags to study the interaction of class 3 viruses including organ and cell type tropism and host responses

Prototype telemetry sensors and behavioural analysis software

Use of nanoparticules for the location and the follow up of inflammatory cells through optical imaging (whole body) and in tissues (confocal microscopy)

Development of high throughput class I MHC genotyping methods for sheep and cattle

Creating ‘Safe Spaces' for research and animal ethics debate

Three webinars available online

Organisation of a 3Rs training event

e-learning platform

Animal infectious disease research, social impact and contributions to the EU bio-based economy

Launch of the structure that will replace VetBioNet after current period of EU funding on the basis of the Sustainability Plan

Adaptation of light sheet confocal microscopy to the imaging of living pathogens and host cells interactions (cell cultures and biopsies)

Two short videos targeting veterinary laboratories and general public

Event targeting Policy makers

Organization of 1 Summer Course at INRA premises

Organization of 1 Summer Course at RI premises

Creation of the Website and communication package

Organization of the final conference and intermediary workshop

Organization of 1 Summer Course at EAAP premises

Organization of 1 Summer Course at IRTA premises

Creation of the Data Management Plan (DMP)

Pubblicazioni

Comparative pathogenesis of peste des petits ruminants virus strains of difference virulence.

Autori: Eloiflin, Roger-Junior; Grau-Roma, Llorenç; Python, Sylvie; Mehinagic, Kemal; Godel, Aurélie; Libeau, Geneviève; Summerfield, Artur; Bataille, Arnaud; García-Nicolás, Obdulio
Pubblicato in: Veterinary Resources, Numero 6, 2022, ISSN 1297-9716
Editore: BMC
DOI: 10.48350/171216

Airway Administration of Flagellin Regulates the Inflammatory Response to Pseudomonas aeruginosa

Autori: Raquel López-Gálvez, Isabelle Fleurot, Pablo Chamero, Sascha Trapp, Michel Olivier, Claire Chevaleyre, Céline Barc, Mickael Riou, Christelle Rossignol, Antoine Guillon, Mustapha Si-Tahar, Tobias May, Pascal Barbry, Andrea Bähr, Nikolai Klymiuk, Jean-Claude Sirard, Ignacio Caballero
Pubblicato in: American Journal of Respiratory Cell and Molecular Biology, 2021, ISSN 1044-1549
Editore: American Lung Association
DOI: 10.1165/rcmb.2021-0125oc

Pathogenicity of Different Betanodavirus RGNNV/SJNNV Reassortant Strains in European Sea Bass

Autori: Lorena Biasini; Paola Berto; Miriam Abbadi; Alessandra Buratin; Marica Toson; Andrea Marsella; Anna Toffan; Francesco Pascoli
Pubblicato in: Pathogens, Numero 20760817, 2022, ISSN 2076-0817
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pathogens11040458

Development and Evaluation of a Duplex Lateral Flow Assay for the Detection and Differentiation between Rabbit Haemorrhagic Disease Virus Lagovirus europaeus/GI.1 and /GI.2

Autori: Alba Fresco-Taboada; Mercedes Montón; Istar Tapia; Elena Soria; Juan Bárcena; Cécile Guillou-Cloarec; Ghislaine Le Gall-Reculé; Esther Blanco; Paloma Rueda
Pubblicato in: Biology, Numero 20797737, 2022, ISSN 2079-7737
Editore: MDPI
DOI: 10.3390/biology11030401

Decrypting the Origin and Pathogenesis in Pregnant Ewes of a New Ovine Pestivirus Closely Related to Classical Swine Fever Virus.

Autori: Miaomiao Wang; Enrica Sozzi; José Alejandro Bohórquez; Mònica Alberch; Joan Pujols; Guillermo Cantero; Alessandra Gaffuri; Davide Lelli; Rosa Rosell; Albert Bensaid; Mariano Domingo; Lester J. Pérez; Ana Moreno; Llilianne Ganges
Pubblicato in: Viruses, Numero 19994915, 2020, ISSN 1999-4915
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v12070775

The molecular basis of differential host responses to avian influenza viruses in avian species with differing susceptibility

Autori: Morris KM, Mishra A, Raut AA, Gaunt ER, Borowska D, Kuo RI, Wang B, Vijayakumar P, Chingtham S, Dutta R, Baillie K, Digard P, Vervelde L, Burt DW and Smith J
Pubblicato in: Frontiers, Numero 2, 2023, ISSN 2235-2988
Editore: Frontiers Media S. A.
DOI: 10.3389/fcimb.2023.1067993

Modulation of lethal HPAIV H5N8 clade 2.3.4.4B infection in AIV pre-exposed mallards

Autori: Susanne Koethe; Lorenz Ulrich; Reiner Ulrich; Susanne Amler; Annika Graaf; Timm C. Harder; Christian Grund; Thomas C. Mettenleiter; Franz Josef Conraths; Martin Beer; Anja Globig
Pubblicato in: Emerging Microbes & Infections, Numero 22221751, 2020, ISSN 2222-1751
Editore: Nature Publishing Group
DOI: 10.1080/22221751.2020.1713706

Comparative pathogenesis of peste des petits ruminants virus strains of difference virulence

Autori: Roger-Junior Eloiflin, Llorenç Grau-Roma, Sylvie Python, Kemal Mehinagic, Aurélie Godel, Geneviève Libeau, Artur Summerfield, Arnaud Bataille, Obdulio García-Nicolás
Pubblicato in: Veterinary Research, Numero 12979716, 2022, ISSN 1297-9716
Editore: Elsevier
DOI: 10.1186/s13567-022-01073-6

Experimental Infection of Cattle with SARS-CoV-2

Autori: Ulrich L., Wernike K., Hoffmann D., Mettenleiter T.C., Beer M.
Pubblicato in: Emerging Infectious Diseases, Numero 10806040, 2020, ISSN 1080-6040
Editore: US National Center for Infectious Diseases
DOI: 10.3201/eid2612.203799

Contemporary selection on MHC genes in a free-living ruminant population

Autori: Huang, W., Dicks, K.L., Hadfield, J.D., Johnston, S.E., Ballingall, K.T., Pemberton, J.M.
Pubblicato in: Ecology Letters, Numero 14610248, 2021, ISSN 1461-0248
Editore: John Wileys & Sons
DOI: 10.1111/ele.13957

A Trifecta of New Insights into Ovine Footrot for Infection Drivers, Immune Response, and Host-Pathogen Interactions

Autori: Blanchard A.M., Staley C.E., Shaw L., Wattegedera S.R., Baumbach C.M., Michler J.K., Rutland C., Back C., Newbold N., Entrican G., Tötemeyer S.
Pubblicato in: Infection and Immunity, Numero 00199567, 2021, ISSN 0019-9567
Editore: American Society for Microbiology
DOI: 10.1128/iai.00270-21

Comparison of three air samplers for the collection of four nebulized respiratory viruses – Collection of respiratory viruses from air

Autori: Jasmin S. Kutter, Dennis de Meulder, Theo M. Bestebroer, Ard Mulders, Ron A.M. Fouchier, Sander Herfst
Pubblicato in: International Journal of Indoor Environment and Health, Numero 17434955, 2021, ISSN 1743-4955
Editore: Inderscience Enterprises
DOI: 10.1111/ina.12875

Viral pathogen-induced mechanisms to antagonize mammalian interferon (IFN) signaling pathway

Autori: José M. Rojas; Alí Alejo; Verónica Martín; Noemí Sevilla
Pubblicato in: Cellular and Molecular Life Sciences, Numero 14209071, 2020, ISSN 1420-9071
Editore: Springer
DOI: 10.1007/s00018-020-03671-z

Differential response of RTGUTGC and RTGILL-W1 rainbow trout epithelial cell lines to viral stimulation

Autori: Rocío Simón; Patricia Martínez; Lucía González; M. Camino Ordás; Carolina Tafalla
Pubblicato in: Journal of Fish Diseases, Numero Volume46, Numero4, 2023, Pagina/e Pages 433-443, ISSN 0140-7775
Editore: Blackwell Publishing Inc.
DOI: 10.1111/jfd.13755

Experimental Infection of Captive Red Foxes (Vulpes vulpes) with Mycobacterium bovis

Autori: Richomme, C., Lesellier, S., Salguero, F.J., Barrat, J.L.; Boucher, J.-M.; Reyes-Reyes, J.D.; Hénault, S.; De Cruz, K.; Tambosco, J.; Michelet, L.; Boutet, J.; Elahi, R.; Lyashchenko, K.P.; O’Halloran, C.; Balseiro, A.; Boschiroli, M.L.
Pubblicato in: Microorganisms, Numero 20762607, 2022, ISSN 2076-2607
Editore: MDPI
DOI: 10.3390/microorganisms10020380

Bovine endometrial MSC: mesenchymal to epithelial transition during luteolysis and tropism to implantation niche for immunomodulation.

Autori: Alexandra Calle; Soraya López-Martín; Marta Monguió-Tortajada; Francesc E. Borràs; María Yáñez-Mó; Miguel Ángel Ramírez
Pubblicato in: Stem Cell Research & Therapy, Numero 17576512, 2019, ISSN 1757-6512
Editore: BioMed Central
DOI: 10.1186/s13287-018-1129-1

Sheep and Cattle Are Not Susceptible to Experimental Inoculation with Hazara Orthonairovirus, a Tick-Borne Arbovirus Closely Related to CCHFV

Autori: Hartlaub J., von Arnim F., Fast C., Somova M., Mirazimi A., Groschup M.H., Keller M.
Pubblicato in: Microorganisms, Numero 20762607, 2020, ISSN 2076-2607
Editore: Basel MDPI
DOI: 10.3390/microorganisms8121927

Identification of Differential Responses of Goat PBMCs to PPRV Virulence Using a Multi-Omics Approach

Autori: Eloiflin, R., Auray, G., Python, S., Rodrigues, V., Seveno, M., Urbach, S., El Koulali, K., Holzmuller, P., Totte, P., Libeau, G., Bataille, A., Summerfield, A.
Pubblicato in: Frontiers in Immunology, Numero 16643224, 2021, ISSN 1664-3224
Editore: Frontiers Media
DOI: 10.3389/fimmu.2021.745315

Deciphering Antibody Responses to Orthonairoviruses in Ruminants

Autori: Hartlaub J., Keller M., Groschup M.H.
Pubblicato in: Microorganisms, Numero 20762607, 2021, ISSN 2076-2607
Editore: Basel MDPI
DOI: 10.3390/microorganisms9071493

SARS-CoV-2 is transmitted via contact and via the air between ferrets.

Autori: Mathilde Richard; Adinda Kok; Dennis de Meulder; Theo M. Bestebroer; Mart M. Lamers; Nisreen M.A. Okba; Martje Fentener van Vlissingen; Barry Rockx; Bart L. Haagmans; Marion Koopmans; Ron A. M. Fouchier; Sander Herfst
Pubblicato in: Nature Communications, Numero 20411723, 2019, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-020-17367-2

Egyptian Fruit Bats (Rousettus aegyptiacus) Were Resistant to Experimental Inoculation with Avian-Origin Influenza A Virus of Subtype H9N2, But Are Susceptible to Experimental Infection with Bat-Borne H9N2 Virus.

Autori: Nico Joel Halwe; Marco Gorka; Bernd Hoffmann; Melanie Rissmann; Angele Breithaupt; Martin Schwemmle; Martin Beer; Ahmed Kandeil; Mohamed A. Ali; Ghazi Kayali; Donata Hoffmann; Anne Balkema-Buschmann
Pubblicato in: Viruses, Numero 5, 2021, ISSN 1999-4915
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13040672

Immunophenotyping of Sheep Paraffin-Embedded Peripheral Lymph Nodes

Autori: Melzi, Eleonora; Rocchi, Mara S.; Entrican, Gary; Caporale, Marco; Palmarini, Massimo
Pubblicato in: Frontiers in Immunology, Numero 16643224, 2018, ISSN 1664-3224
Editore: Frontiers Media
DOI: 10.3389/fimmu.2018.02892

A Systematic Evaluation of High-Throughput Sequencing Approaches to Identify Low-Frequency Single Nucleotide Variants in Viral Populations

Autori: King D.J., Freimanis G., Lasecka-Dykes L., Asfor A., Ribeca P., Waters R., King D.P., Laing E.
Pubblicato in: Viruses, Numero 19994915, 2020, ISSN 1999-4915
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v12101187

Embryonic Trophectoderm Secretomics Reveals Chemotactic Migration and Intercellular Communication of Endometrial and Circulating MSCs in Embryonic Implantation.

Autori: Alexandra Calle; Víctor Toribio; María Yáñez-Mó; Miguel Ángel Ramírez
Pubblicato in: International Journal of Molecular Sciences, Numero 14220067, 2021, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.21203/rs.3.rs-177701/v1

High sensitivity of domestic pigs to intravenous infection with HEV

Autori: Lisa Dähnert; Martin Eiden; Josephine Schlosser; Christine Fast; Charlotte Schröder; Elke Lange; Albrecht Gröner; Wolfram Schäfer; Martin H. Groschup
Pubblicato in: BMC Veterinary Research, Numero 17466148, 2018, ISSN 1746-6148
Editore: BioMed Central
DOI: 10.1186/s12917-018-1713-8

Activation of OX40 and CD27 Costimulatory Signalling in Sheep through Recombinant Ovine Ligands

Autori: Rojas J.M., Alejo A., Avia J.M., Rodríguez-Martín D., Sánchez C., Alcamí A., Sevilla N., Martín V.
Pubblicato in: Vaccines, Numero 2076393X, 2020, ISSN 2076-393X
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines8020333

Long-Term Protection and Serologic Response of European SeaBass Vaccinated with a Betanodavirus Virus-Like Particle Produced in Pichia pastoris

Autori: Sofie Barsøe, Anna Toffan, Francesco Pascoli, Ansgar Stratmann, Tobia Pretto, Andrea Marsella, Mériem Er-Rafik, Niccolò Vendramin, Niels J. Olesen, Dagoberto Sepúlveda, Niels Lorenzen
Pubblicato in: Vaccines, Numero 2076393X, 2021, ISSN 2076-393X
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines9050447

Bovine Herpesvirus-4-Vectored Delivery of Nipah Virus Glycoproteins Enhances T Cell Immunogenicity in Pigs

Autori: Pedrera M., Macchi F., McLean R.K., Franceschi V., Thakur N., Russo L., Medfai L., Todd S., Tchilian E.Z., Audonnet J.C., Chappell K., Isaacs A., Watterson D., Young P.R., Marsh G.A., Bailey D., Graham S.P., Donofrio G.
Pubblicato in: Vaccines, Numero 2076393X, 2020, ISSN 2076-393X
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines8010115

In vivo imaging reveals novel replication sites of a highly oncogenic avian herpesvirus in chickens

Autori: Isabelle Lantier, Corentin Mallet, Laurent Souci, Thibaut Larcher, Andele M. Conradie, Katia Courvoisier, Sascha Trapp, David Pasdeloup, Benedikt B. Kaufer, Caroline Denesvre
Pubblicato in: PLOS Pathogens, Numero 15537374, 2022, ISSN 1553-7374
Editore: PLOS
DOI: 10.1371/journal.ppat.1010745

Characterisation of major histocompatibility complex class IIa haplotypes in an island sheep population.

Autori: Kara L. Dicks; Josephine M. Pemberton; Keith T. Ballingall
Pubblicato in: Immunogenetics, Numero 00937711, 2019, ISSN 0093-7711
Editore: Springer Verlag
DOI: 10.1007/s00251-019-01109-w

Vaccination With Recombinant Adenoviruses Expressing the Bluetongue Virus Subunits VP7 and VP2 Provides Protection Against Heterologous Virus Challenge.

Autori: José M. Rojas; Diego Barba-Moreno; Miguel Avia; Noemí Sevilla; Verónica Martín
Pubblicato in: Frontiers in Veterinary Science, Numero 22971769, 2021, ISSN 2297-1769
Editore: Frontiers Media
DOI: 10.3389/fvets.2021.645561

Long term dietary vitamin D3 supplementation impacts both microbicidal and inflammatory responses to ex-vivo Mycobacterium bovis BCG challenge in dairy calves

Autori: Susana Flores-Villalva, Cian Reid, Aude Remot, Stephen V. Gordon, Kieran G. Meade
Pubblicato in: ScienceDirect, Numero 8, 2023, ISSN 0165-2427
Editore: Elsevier BV
DOI: 10.1016/j.vetimm.2023.110575

Ex vivo rescue of recombinant very virulent IBDV using a RNA polymerase II driven system and primary chicken bursal cells

Autori: Liliana L. Cubas-Gaona, Romane Trombetta, Céline Courtillon, Kai Li, Xiaole Qi, Xiaomei Wang, Sofiane Lotmani, Alassane Keita, Michel Amelot, Nicolas Eterradossi, Sébastien Mathieu Soubies
Pubblicato in: Scientific Reports, Numero 20452322, 2020, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-020-70095-x

Defining immune correlates during latent and active chlamydial infection in sheep

Autori: Sean Wattegedera; Morag Livingstone; Stephen Maley; Mara Rocchi; Susan Lee; Yvonne Pang; Nick Wheelhouse; Kevin Aitchison; Javier Palarea-Albaladejo; David Buxton; David Longbottom; Gary Entrican
Pubblicato in: Veterinary Research, Pp 1-18 (2020), Numero 17466148, 2020, ISSN 1746-6148
Editore: BioMed Central
DOI: 10.1186/s13567-020-00798-6

Detection of MERS-CoV antigen on formalin-fixed paraffin-embedded nasal tissue of alpacas by immunohistochemistry using human monoclonal antibodies directed against different epitopes of the spike protein.

Autori: Haverkamp, Ann-Kathrin; Bosch, Berend J; Spitzbarth, Ingo; Lehmbecker, Annika; Te, Nigeer; Bensaid, Albert; Segalés, Joaquim; Baumgärtner, Wolfgang; dI&I I&I-1; LS Virologie
Pubblicato in: Veterinary Immunology and Immunopathology, Numero 18732534, 2019, ISSN 1873-2534
Editore: Springer
DOI: 10.1016/j.vetimm.2019.109939

Animal Models for the Study of Nucleic Acid Immunity: Novel Tools and New Perspectives.

Autori: Isabelle K. Vila; Maxence Frétaud; Dimitrios Vlachakis; Nadine Laguette; Christelle Langevin
Pubblicato in: Journal of Molecular Biology, Numero 00222836, 2020, ISSN 0022-2836
Editore: Academic Press
DOI: 10.1016/j.jmb.2020.08.016

Diagnosis and Pathogenesis of Nairobi Sheep Disease Orthonairovirus Infections in Sheep and Cattle

Autori: Hartlaub J., Gutjahr B., Fast C., Mirazimi A., Keller M., Groschup M.H.
Pubblicato in: Viruses, Numero 19994915, 2021, ISSN 1999-4915
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13071250

Non-Lethal Sequential Individual Monitoring of Viremia in Relation to DNA Vaccination in Fish-Example Using a Salmon Alphavirus DNA Vaccine in Atlantic Salmon Salmo salar .

Autori: Catherine M. Collins; Katherine Lester; Jorge Del-Pozo; Bertrand Collet; Bertrand Collet
Pubblicato in: Vaccines, Numero 2076393X, 2021, ISSN 2076-393X
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines9020163

Mycobacterial Infection of Precision-Cut Lung Slices Reveals Type 1 Interferon Pathway Is Locally Induced by Mycobacterium bovis but Not M. tuberculosis in a Cattle Breed

Autori: Aude Remot, Florence Carreras, Anthony Coupé, Émilie Doz-Deblauwe, Maria L. Boschiroli, John A. Browne, Quentin Marquant, Delphyne Descamps, Fabienne Archer, Abraham Aseffa, Pierre Germon, Stephen V. Gordon, Nathalie Winter
Pubblicato in: Frontiers in Veterinary Science, Numero 22971769, 2021, ISSN 2297-1769
Editore: Frontiers Media
DOI: 10.3389/fvets.2021.696525

Shuni Virus Replicates at the Maternal-Fetal Interface of the Ovine and Human Placenta

Autori: Judith Oymans; Lucien van Keulen; Guus M. Vermeulen; Paul J. Wichgers Schreur; Jeroen Kortekaas
Pubblicato in: Pathogens, Numero 20760817, 2020, ISSN 2076-0817
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pathogens10010017

High throughput analysis of MHC-I and MHC-DR diversity of Brazilian cattle populations

Autori: Deepali Vasoya, Priscila Silva Oliveira, Laura Agundez Muriel, Thomas Tzelos, Christina Vrettou, W. Ivan Morrison, Isabel Kinney Ferreira de Miranda Santos, Timothy Connelley
Pubblicato in: HLA, Numero 20592302, 2021, ISSN 2059-2302
Editore: John Wiley & Sons
DOI: 10.1111/tan.14339

Cryobanking European Mink (Mustela lutreola) Mesenchymal Stem Cells and Oocytes

Autori: Calle A., Ramírez M.Á.
Pubblicato in: International Journal of Molecular Sciences, Numero 14220067, 2022, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23169319

Comparative Analysis of Different Inbred Chicken Lines Highlights How a Hereditary Inflammatory State Affects Susceptibility to Avian Influenza Virus

Autori: Bryson, K.J.; Sives, S.; Lee, H.-M.; Borowska, D.; Smith, J.; Digard, P.; Vervelde, L.
Pubblicato in: Viruses, Numero 5, 2023, ISSN 1999-4915
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v15030591

Efficacy Assessment of Newly-designed Filtering Facemasks during the SARS-CoV-2 Pandemic

Autori: Bob Boogaard, Ali Tas, Joep Nijssen, Freek Broeren, John van der Dobbelsteen, Vincent Verhoeven, Jip Pluim, Sing Dekker, Eric Snijder, Martijn van Hemert, Sander Herfst
Pubblicato in: Aerosol Air Quality Research, Numero 16808584, 2021, ISSN 1680-8584
Editore: Chinese Association for Aerosol Research in Taiwan
DOI: 10.4209/aaqr.2020.07.0424

Protective efficacy of an RBD-based Middle East respiratory syndrome coronavirus (MERS-CoV) particle vaccine in llamas

Autori: Jordi Rodon, Anna Z. Mykytyn, Guillermo Cantero, Irina C. Albulescu, Berend-Jan Bosch, Alexander Brix, Jean-Christophe Audonnet, Albert Bensaid, Júlia Vergara-Alert, Bart L. Haagmans, Joaquim Segalés
Pubblicato in: One Health Outlook, Numero 25244655, 2022, ISSN 2524-4655
Editore: BMC part of Springer Nature
DOI: 10.1186/s42522-022-00068-9

A New Look at Vaccine Strategies Against PPRV Focused on Adenoviral Candidates

Autori: José M. Rojas, Noemí Sevilla, Verónica Martín
Pubblicato in: Frontiers in Veterinary Science, Numero 22971769, 2021, ISSN 2297-1769
Editore: Frontiers Media
DOI: 10.3389/fvets.2021.729879

Reverse genetics system for shuni virus, an emerging orthobunyavirus with zoonotic potential

Autori: Judith Oymans; Paul J. Wichgers Schreur; Sophie van Oort; R.P.M. Vloet; Marietjie Venter; Gorben P. Pijlman; Monique M. van Oers; Jeroen Kortekaas
Pubblicato in: Viruses, Numero 19994915, 2020, ISSN 1999-4915
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v12040455

High-Resolution, 3D Imaging of the Zebrafish Gill-Associated Lymphoid Tissue (GIALT) Reveals a Novel Lymphoid Structure, the Amphibranchial Lymphoid Tissue

Autori: Alf Seljenes Dalum; Aurora Kraus; Shanawaz Khan; Erna Davydova; Dimitri Rigaudeau; Håvard Bjørgen; Adrián López-Porras; Gareth Griffiths; Geert F. Wiegertjes; Erling Olaf Koppang; Irene Salinas; Pierre Boudinot; Julien Rességuier
Pubblicato in: Frontiers in immunology, Numero 16643224, 2021, ISSN 1664-3224
Editore: Frontiers Media
DOI: 10.3389/fimmu.2021.769901

Cross-Reaction or Co-Infection? Serological Discrimination of Antibodies Directed against Dugbe and Crimean-Congo Hemorrhagic Fever Orthonairovirus in Nigerian Cattle

Autori: Hartlaub J., Daodu O.B., Sadeghi B., Keller M., Olopade J., Oluwayelu D., Groschup M.H.
Pubblicato in: Viruses, Numero 19994915, 2021, ISSN 1999-4915
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13071398

Improving Tumor Retention of Effector Cells in Adoptive Cell Transfer Therapies by Magnetic Targeting.

Autori: Laura Sanz-Ortega; José M. Rojas; Domingo F. Barber
Pubblicato in: Pharmaceutics, Numero 19994923, 2020, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics12090812

Comparison of Biological Features of Wild European Rabbit Mesenchymal Stem Cells Derived from Different Tissues

Autori: Calle A., Zamora-Ceballos M., Bárcena J., Blanco E., Ramírez M.Á.
Pubblicato in: International Journal of Molecular Sciences, Numero 14220067, 2022, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23126420

Iberian pig mesenchymal stem/stromal cells from dermal skin, abdominal and subcutaneous adipose tissues, and peripheral blood: in vitro characterization and migratory properties in inflammation

Autori: Alexandra Calle, Clara Barrajón-Masa, Ernesto Gómez-Fidalgo, Mercedes Martín-Lluch, Paloma Cruz-Vigo, Raúl Sánchez-Sánchez, Miguel Ángel Ramírez
Pubblicato in: Stem Cell Research & Therapy, Numero 9/1, 2018, ISSN 1757-6512
Editore: BioMed Central
DOI: 10.1186/s13287-018-0933-y

IPD-MHC: nomenclature requirements for the non-human major histocompatibility complex in the next-generation sequencing era

Autori: Giuseppe Maccari, James Robinson, Ronald E. Bontrop, Nel Otting, Natasja G. de Groot, Chak-Sum Ho, Keith T. Ballingall, Steven G. E. Marsh, John A. Hammond
Pubblicato in: Immunogenetics, Numero 70/10, 2018, Pagina/e 619-623, ISSN 0093-7711
Editore: Springer Verlag
DOI: 10.1007/s00251-018-1072-4

Propagation and titration of infectious bursal disease virus, including non-cell-culture-adapted strains, using ex vivo -stimulated chicken bursal cells

Autori: Sébastien Mathieu Soubies, Céline Courtillon, Mouna Abed, Michel Amelot, Alassane Keita, Andrew Broadbent, Sonja Härtle, Bernd Kaspers, Nicolas Eterradossi
Pubblicato in: Avian Pathology, Numero 47/2, 2017, Pagina/e 179-188, ISSN 0307-9457
Editore: Taylor & Francis
DOI: 10.1080/03079457.2017.1393044

Blocking transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) in llamas by vaccination with a recombinant spike protein

Autori: Jordi Rodon, Nisreen M. A. Okba, Nigeer Te, Brenda van Dieren, Berend-Jan Bosch, Albert Bensaid, Joaquim Segalés, Bart L. Haagmans, Júlia Vergara-Alert
Pubblicato in: Emerging Microbes & Infections, Numero 8/1, 2019, Pagina/e 1593-1603, ISSN 2222-1751
Editore: Nature Publishing Group
DOI: 10.1080/22221751.2019.1685912

Highly multiplexed quantitative PCR-based platform for evaluation of chicken immune responses

Autori: Dominika Borowska, Richard Kuo, Richard A. Bailey, Kellie A. Watson, Pete Kaiser, Lonneke Vervelde, Mark P. Stevens
Pubblicato in: PLOS ONE, Numero 14/12, 2019, Pagina/e e0225658, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0225658

Allelic nomenclature for the duplicated MHC class II DQ genes in sheep

Autori: Keith T. Ballingall, Kara Dicks, Panoraia Kyriazopoulou, Lynne Herrmann-Hoesing
Pubblicato in: Immunogenetics, Numero 71/4, 2019, Pagina/e 347-351, ISSN 0093-7711
Editore: Springer Verlag
DOI: 10.1007/s00251-018-1096-9

Immunological Homeostasis at the Ovine Placenta May Reflect the Degree of Maternal Fetal Interaction

Autori: Sean R. Wattegedera, Laura E. Doull, Mariya I. Goncheva, Nicholas M. Wheelhouse, Donna M. Watson, Julian Pearce, Julio Benavides, Javier Palarea-Albaladejo, Colin J. McInnes, Keith Ballingall, Gary Entrican
Pubblicato in: Frontiers in Immunology, Numero 9, 2019, ISSN 1664-3224
Editore: .
DOI: 10.3389/fimmu.2018.03025

Precision cut lung slices: a novel versatile tool to examine host–pathogen interaction in the chicken lung

Autori: Karen Jane Bryson, Damien Garrido, Marco Esposito, Gerry McLachlan, Paul Digard, Catherine Schouler, Rodrigo Guabiraba, Sascha Trapp, Lonneke Vervelde
Pubblicato in: Veterinary Research, Numero 51/1, 2020, ISSN 1297-9716
Editore: .
DOI: 10.1186/s13567-019-0733-0

Chicken endothelial cells are highly responsive to viral innate immune stimuli and are susceptible to infections with various avian pathogens

Autori: Adrien Lion, Evelyne Esnault, Emmanuel Kut, Vanaïque Guillory, Laetitia Trapp-Fragnet, Sébastien M. Soubies, Nathalie Chanteloup, Alisson Niepceron, Rodrigo Guabiraba, Daniel Marc, Nicolas Eterradossi, Sascha Trapp, Pascale Quéré
Pubblicato in: Avian Pathology, Numero 48/2, 2018, Pagina/e 121-134, ISSN 0307-9457
Editore: Taylor & Francis
DOI: 10.1080/03079457.2018.1556386

Experimental Challenge of Sheep and Cattle with Dugbe Orthonairovirus, a Neglected African Arbovirus Distantly Related to CCHFV

Autori: Hartlaub J., von Arnim F., Fast C., Mirazimi A., Keller M., Groschup M.H.
Pubblicato in: Viruses, Numero 19994915, 2021, ISSN 1999-4915
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v13030372

Intramuscular DNA Vaccination of Juvenile Carp against Spring Viremia of Carp Virus Induces Full Protection and Establishes a Virus-Specific B and T Cell Response

Autori: Carmen W.E. Embregts; Dimitri Rigaudeau; Tomáš Veselý; Dagmar Pokorova; Niels Lorenzen; Jules Petit; Armel Houel; Malte Dauber; Heike Schütze; Pierre Boudinot; Geert F. Wiegertjes; Maria Forlenza
Pubblicato in: Frontiers in Immunology, Numero 16643224, 2017, ISSN 1664-3224
Editore: Frontiers Media
DOI: 10.3389/fimmu.2017.01340

Mesenchymal Stem Cells in Embryo-Maternal Communication under Healthy Conditions or Viral Infections: Lessons from a Bovine Model

Autori: Alexandra Calle; Miguel Ángel Ramírez
Pubblicato in: Cells, Numero 20734409, 2022, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells11121858

Type I and III IFNs produced by the nasal epithelia and dimmed inflammation are features of alpacas resolving MERS-CoV infection

Autori: Nigeer Te Jordi Rodon, Maria Ballester, Mónica Pérez, Lola Pailler-García, Joaquim Segalés, Júlia Vergara-Alert, Albert Bensaid
Pubblicato in: PLOS Pathogens, Numero 15537366, 2021, ISSN 1553-7366
Editore: Public Library of Science
DOI: 10.1371/journal.ppat.1009229

Evaluation of alpaca tracheal explants as an ex vivo model for the study of Middle East respiratory syndrome coronavirus (MERS-CoV) infection

Autori: Nigeer Te; Jordi Rodon; Rhea Creve; Mónica Pérez; Joaquim Segalés; Júlia Vergara-Alert; Albert Bensaid
Pubblicato in: Veterinary Research, Numero 12979716, 2022, ISSN 1297-9716
Editore: Springer Nature
DOI: 10.1186/s13567-022-01084-3

Immunization With Bovine Herpesvirus-4-Based Vector Delivering PPRV-H Protein Protects Sheep From PPRV Challenge

Autori: Daniel Rodríguez-Martín, José Manuel Rojas, Francesca Macchi, Valentina Franceschi, Luca Russo, Noemí Sevilla, Gaetano Donofrío, Verónica Martín
Pubblicato in: Frontiers in Immunology, Numero 16643224, 2021, ISSN 1664-3224
Editore: Lausanne Frontiers Media
DOI: 10.3389/fimmu.2021.705539

SARS-CoV and SARS-CoV-2 are transmitted through the air between ferrets over more than one meter distance.

Autori: Jasmin S Kutter; Dennis de Meulder; Theo M. Bestebroer; Pascal Lexmond; Ard Mulders; Mathilde Richard; Ron A. M. Fouchier; Sander Herfst
Pubblicato in: Nature Communications, Numero 20411723, 2021, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-021-21918-6

Uncovering the core principles of the gut-lung axis to enhance innate immunity in the chicken

Autori: Saint-Martin V., Quéré P., Trapp S., Guabiraba R.
Pubblicato in: Frontiers in Immunology, Numero 16643224, 2022, ISSN 1664-3224
Editore: Frontiers Media
DOI: 10.3389/fimmu.2022.956670

Enhanced replication fitness of MERS-CoV clade B over clade A strains in camelids explains the dominance of clade B strains in the Arabian Peninsula

Autori: Nigeer Te, Jordi Rodon, Mónica Pérez, Joaquim Segalés, Júlia Vergara-Alert, Albert Bensaid
Pubblicato in: Emerging Microbes & Infections, Numero 22221751, 2022, ISSN 2222-1751
Editore: Nature Publishing Group
DOI: 10.1080/22221751.2021.2019559

Hemagglutinin protein of Peste des Petits Ruminants virus (PPRV) activates the innate immune response via Toll-like receptor 2 signaling

Autori: José M. Rojas, Elena Pascual, Sean R. Wattegedera, Miguel Avia, César Santiago, Verónica Martín, Gary Entrican, Noemí Sevilla
Pubblicato in: Virulence, Numero 21505594, 2021, ISSN 2150-5594
Editore: Landes Bioscience
DOI: 10.1080/21505594.2021.1882246

The Intrinsic Biological Identities of Iron Oxide Nanoparticles and Their Coatings: Unexplored Territory for Combinatorial Therapies

Autori: Mulens-Arias V., Rojas J.M., Barber D.F.
Pubblicato in: Nanomaterials, Numero 20794991, 2020, ISSN 2079-4991
Editore: Basel MDPI AG
DOI: 10.3390/nano10050837

Erysipelothrix rhusiopathiae-specific T-cell responses after experimental infection of chickens selectively bred for high and low serum levels of mannose-binding lectin

Autori: Wattrang, E., Sørensen Dalgaard, T., Brødsgaard Kjaerup, R. et al.
Pubblicato in: Veterinary Research, 2022, ISSN 1297-9716
Editore: Unknown

Cyclic Guanosine Monophosphate–Adenosine Monophosphate Synthase (cGAS), a Multifaceted Platform of Intracellular DNA Sensing

Autori: Eloi R. Verrier, Christelle Langevin
Pubblicato in: Frontiers in Immunology, Numero 16643224, 2021, ISSN 1664-3224
Editore: Frontiers Media
DOI: 10.3389/fimmu.2021.637399

Genome Evolution of Two Genetically Homogeneous Infectious Bursal Disease Virus Strains During Passages in vitro and ex vivo in the Presence of a Mutagenic Nucleoside Analog

Autori: Liliana L. Cubas-Gaona, Alexandre Flageul, Céline Courtillon, Francois-Xavier Briand, Maud Contrant, Stephanie Bougeard, Pierrick Lucas, Hélène Quenault, Aurélie Leroux, Alassane Keita, Michel Amelot, Béatrice Grasland, Yannick Blanchard, Nicolas Eterradossi, Paul Alun Brown, Sébastien Mathieu Soubies
Pubblicato in: Frontiers in Microbiology, Numero 1664302X, 2021, ISSN 1664-302X
Editore: Frontiers Media
DOI: 10.3389/fmicb.2021.678563

Potential Role of Different Fish Species as Vectors of Koi Herpesvirus (CyHV-3) Infection

Autori: Marek Matras, Magdalena Stachnik, Ewa Borzym, Joanna Maj-Paluch, Michał Reichert
Pubblicato in: Journal of Veterinary Research, Numero 24508608, 2019, ISSN 2450-8608
Editore: Warsaw De Gruyter Open
DOI: 10.2478/jvetres-2019-0069

Role of Rotifers in Betanodavirus Transmission to European Sea Bass Larvae

Autori: Vázquez-Salgado L., Pascoli F., Marsella A., Biasini L., Buratin A., Pretto T., Abbadi M., Melchiotti E., Bandín I., Toffan A.
Pubblicato in: Frontiers in Veterinary Science, Numero 22971769, 2022, ISSN 2297-1769
Editore: Frontiers Media
DOI: 10.3389/fvets.2022.932327

Adenovirus as Tools in Animal Health

Autori: José M. Rojas; Noemí Sevilla; Verónica Martín
Pubblicato in: Adenoviruses, 2019, ISBN 978-1-78984-991-2
Editore: IntechOpen Limited
DOI: 10.5772/intechopen.79132

In Vivo Tracking of Bacterial Colonization in Different Murine Models Using Bioluminescence: The Example of Salmonella

Autori: Michaël Koczerka, Isabelle Lantier, Anne Pinard, Marie Morillon, Justine Deperne, Ohad Gal-Mor, Olivier Grépinet, Isabelle Virlogeux-Payant
Pubblicato in: Bacterial Virulence, 2022, Pagina/e pag. 235-248, ISBN 978-1-0716-1970-4
Editore: Humana
DOI: 10.1007/978-1-0716-1971-1_19

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