Neurologic and Psychiatric Disorders: from synapses to networks

Risultati finali

Public sessions debates on neuroscientific topics with societal impact quantified and assessed
1st Annual Scientific Meeting (kickoff meeting) announced and programmed
3rd Annual Scientific Meeting accomplished
4th Annual Scientific Meeting accomplished

4th (Final) Annual Scientific Meeting accomplished. This will be the final scientific meeting of SynaNet

Participation of students from the University of Lisbon at the Workshops, Lectures and seminars promoted by SynaNet members quantified (3rd year)
Participation of students from the University of Lisbon at the Workshops, Lectures and seminars promoted by SynaNet members quantified (1st year)
Joint projects and student co-supervision between SynaNet in particular in the areas of interface between different disciplines quantified
2nd Annual Scientific Meeting accomplished
Participation of students from the University of Lisbon at the Workshops, Lectures and seminars promoted by SynaNet members quantified (2nd)

Participation of students from the University of Lisbon at the Workshops, Lectures and seminars promoted by SynaNet members quantified (2nd year)

SynaNet webpage made visible

Pubblicazioni

Dual Influence of Endocannabinoids on Long-Term Potentiation of Synaptic Transmission

Autori: Armando Silva-Cruz, Mattias Carlström, Joaquim A. Ribeiro, Ana M. Sebastião
Pubblicato in: Frontiers in Pharmacology, Numero 8, 2017, ISSN 1663-9812
Editore: Frontiers Media S.A.
DOI: 10.3389/fphar.2017.00921

Interaction between Cannabinoid Type 1 and Type 2 Receptors in the Modulation of Subventricular Zone and Dentate Gyrus Neurogenesis

Autori: Rui S. Rodrigues, Filipa F. Ribeiro, Filipa Ferreira, Sandra H. Vaz, Ana M. Sebastião, Sara Xapelli
Pubblicato in: Frontiers in Pharmacology, Numero 8, 2017, ISSN 1663-9812
Editore: Frontiers Media S.A.
DOI: 10.3389/fphar.2017.00516

Scalable, Lightweight, Integrated and Quick-to-Assemble (SLIQ) Hyperdrives for Functional Circuit Dissection

Autori: Li Liang, Stefan N. Oline, Justin C. Kirk, Lukas Ian Schmitt, Robert W. Komorowski, Miguel Remondes, Michael M. Halassa
Pubblicato in: Frontiers in Neural Circuits, Numero 11, 2017, ISSN 1662-5110
Editore: Frontiers Research Foundation
DOI: 10.3389/fncir.2017.00008

Chronic and acute adenosine A2A receptor blockade prevents long-term episodic memory disruption caused by acute cannabinoid CB1 receptor activation

Autori: Francisco M. Mouro, Vânia L. Batalha, Diana G. Ferreira, Joana E. Coelho, Younis Baqi, Christa E. Müller, Luísa V. Lopes, Joaquim A. Ribeiro, Ana M. Sebastião
Pubblicato in: Neuropharmacology, Numero 117, 2017, Pagina/e 316-327, ISSN 0028-3908
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2017.02.021

Downregulated Glia Interplay and Increased miRNA-155 as Promising Markers to Track ALS at an Early Stage

Autori: Carolina Cunha, Catarina Santos, Cátia Gomes, Adelaide Fernandes, Alexandra Marçal Correia, Ana Maria Sebastião, Ana Rita Vaz, Dora Brites
Pubblicato in: Molecular Neurobiology, 2018, ISSN 0893-7648
Editore: Humana Press, Inc.
DOI: 10.1007/s12035-017-0631-2

Inhibition of NMDA Receptors Prevents the Loss of BDNF Function Induced by Amyloid β

Autori: Sara R. Tanqueiro, Rita M. Ramalho, Tiago M. Rodrigues, Luísa V. Lopes, Ana M. Sebastião, Maria J. Diógenes
Pubblicato in: Frontiers in Pharmacology, Numero 9, 2018, ISSN 1663-9812
Editore: Frontiers Media S.A.
DOI: 10.3389/fphar.2018.00237

Enhanced LTP in aged rats: Detrimental or compensatory?

Autori: Júlia Pinho, Ruben Vale, Vânia L. Batalha, Ana Rita Costenla, Raquel Dias, Diogo Rombo, Ana M. Sebastião, Alexandre de Mendonça, Maria José Diógenes
Pubblicato in: Neuropharmacology, Numero 114, 2017, Pagina/e 12-19, ISSN 0028-3908
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2016.11.017

Ex vivo model of epilepsy in organotypic slices—a new tool for drug screening

Autori: Daniela M. Magalhães, Noémia Pereira, Diogo M. Rombo, Cláudia Beltrão-Cavacas, Ana M. Sebastião, Cláudia A. Valente
Pubblicato in: Journal of Neuroinflammation, Numero 15/1, 2018, ISSN 1742-2094
Editore: BioMed Central
DOI: 10.1186/s12974-018-1225-2

Platinum Nanoparticle-Based Microreactors as Support for Neuroblastoma Cells

Autori: Ana Armada-Moreira, Essi Taipaleenmäki, Marie Baekgaard-Laursen, Philipp Sebastian Schattling, Ana M. Sebastião, Sandra H. Vaz, Brigitte Städler
Pubblicato in: ACS Applied Materials & Interfaces, Numero 10/9, 2018, Pagina/e 7581-7592, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.1021/acsami.7b10724

Tauroursodeoxycholic Acid Enhances Mitochondrial Biogenesis, Neural Stem Cell Pool, and Early Neurogenesis in Adult Rats

Autori: Rita Soares, Filipa F. Ribeiro, Sara Xapelli, Tânia Genebra, Maria F. Ribeiro, Ana M. Sebastião, Cecília M. P. Rodrigues, Susana Solá
Pubblicato in: Molecular Neurobiology, 2018, ISSN 0893-7648
Editore: Humana Press, Inc.
DOI: 10.1007/s12035-017-0592-5

GAT-3 Dysfunction Generates Tonic Inhibition in External Globus Pallidus Neurons in Parkinsonian Rodents

Autori: Marine Chazalon, Elena Paredes-Rodriguez, Stéphanie Morin, Audrey Martinez, Sofia Cristóvão-Ferreira, Sandra Vaz, Ana Sebastiao, Aude Panatier, Eric Boué-Grabot, Cristina Miguelez, Jérôme Baufreton
Pubblicato in: Cell Reports, Numero 23/6, 2018, Pagina/e 1678-1690, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2018.04.014

Glycine Receptor Activation Impairs ATP-Induced Calcium Transients in Cultured Cortical Astrocytes

Autori: Tatiana P. Morais, David Coelho, Sandra H. Vaz, Ana M. Sebastião, Cláudia A. Valente
Pubblicato in: Frontiers in Molecular Neuroscience, Numero 10, 2018, ISSN 1662-5099
Editore: Frontiers Research Foundation
DOI: 10.3389/fnmol.2017.00444

Constrained Nonlinear-Based Optimisation Applied to Fuzzy PID Controllers Tuning

Autori: Paulo Gil, Ana Sebastião, Catarina Lucena
Pubblicato in: Asian Journal of Control, Numero 20/1, 2018, Pagina/e 135-148, ISSN 1561-8625
Editore: Chinese Automatic Control Society
DOI: 10.1002/asjc.1549

VPAC 1 and VPAC 2 receptor activation on GABA release from hippocampal nerve terminals involve several different signalling pathways

Autori: Diana Cunha-Reis, Joaquim Alexandre Ribeiro, Rodrigo F M de Almeida, Ana M Sebastião
Pubblicato in: British Journal of Pharmacology, Numero 174/24, 2017, Pagina/e 4725-4737, ISSN 0007-1188
Editore: Wiley-Blackwell
DOI: 10.1111/bph.14051

On the role of stigmergy in cognition

Autori: Luís Correia, Ana M. Sebastião, Pedro Santana
Pubblicato in: Progress in Artificial Intelligence, Numero 6/1, 2017, Pagina/e 79-86, ISSN 2192-6352
Editore: SPRINGER HEIDELBERG
DOI: 10.1007/s13748-016-0107-z

Dissecting neurovascular coupling mechanisms: a role for adenosine A 2A receptor

Autori: Nicholas Dale, Ana Maria Sebastião
Pubblicato in: Journal of Neurochemistry, Numero 140/1, 2017, Pagina/e 10-12, ISSN 0022-3042
Editore: Blackwell Publishing Inc.
DOI: 10.1111/jnc.13896

Broad spectrum antiviral activity for paramyxoviruses is modulated by biophysical properties of fusion inhibitory peptides

Autori: Cyrille Mathieu, Marcelo T. Augusto, Stefan Niewiesk, Branka Horvat, Laura M. Palermo, Giuseppina Sanna, Silvia Madeddu, Devra Huey, Miguel A. R. B. Castanho, Matteo Porotto, Nuno C. Santos, Anne Moscona
Pubblicato in: Scientific Reports, Numero 7/1, 2017, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/srep43610

In Vivo Efficacy of Measles Virus Fusion Protein-Derived Peptides Is Modulated by the Properties of Self-Assembly and Membrane Residence

Autori: T. N. Figueira, L. M. Palermo, A. S. Veiga, D. Huey, C. A. Alabi, N. C. Santos, J. C. Welsch, C. Mathieu, B. Horvat, S. Niewiesk, A. Moscona, M. A. R. B. Castanho, M. Porotto
Pubblicato in: Journal of Virology, Numero 91/1, 2016, ISSN 0022-538X
Editore: American Society for Microbiology
DOI: 10.1128/jvi.01554-16

siRNA-cell-penetrating peptides complexes as a combinatorial therapy against chronic myeloid leukemia using BV173 cell line as model

Autori: Freire, JM (Freire, Joao Miguel)[ 1 ] ; de Figueiredo, IR (de Figueiredo, Ines Rego)[ 1 ] ; Valle, J (Valle, Javier)[ 2 ] ; Veiga, AS (Veiga, Ana Salome)[ 1 ] ; Andreu, D (Andreu, David)[ 2 ] ; Enguita, FJ (Enguita, Francisco J.)[ 1 ] ; Castanho, MARB (Castanho, Miguel A. R. B.)[ 1 ]
Pubblicato in: JOURNAL OF CONTROLLED RELEASE, 2017, ISSN 0168-3659
Editore: Elsevier BV
DOI: 10.1016/j.jconrel.2016.11.027

New Potent Membrane-Targeting Antibacterial Peptides from Viral Capsid Proteins

Autori: Susana A. Dias, João M. Freire, Clara Pérez-Peinado, Marco M. Domingues, Diana Gaspar, Nuno Vale, Paula Gomes, David Andreu, Sónia T. Henriques, Miguel A. R. B. Castanho, Ana S. Veiga
Pubblicato in: Frontiers in Microbiology, Numero 8, 2017, ISSN 1664-302X
Editore: Frontiers Media
DOI: 10.3389/fmicb.2017.00775

A New Noncanonical Anionic Peptide That Translocates a Cellular Blood–Brain Barrier Model

Autori: Sara Neves-Coelho, Rute Eleutério, Francisco Enguita, Vera Neves, Miguel Castanho
Pubblicato in: Molecules, Numero 22/10, 2017, Pagina/e 1753, ISSN 1420-3049
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules22101753

Mechanisms of bacterial membrane permeabilization by crotalicidin (Ctn) and its fragment Ctn(15–34), antimicrobial peptides from rattlesnake venom

Autori: Clara Pérez-Peinado, Susana Almeida Dias, Marco M. Domingues, Aurélie H. Benfield, João Miguel Freire, Gandhi Rádis-Baptista, Diana Gaspar, Miguel A. R. B. Castanho, David J. Craik, Sónia Troeira Henriques, Ana Salomé Veiga, David Andreu
Pubblicato in: Journal of Biological Chemistry, Numero 293/5, 2018, Pagina/e 1536-1549, ISSN 0021-9258
Editore: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/jbc.ra117.000125

Novel Peptides Derived from Dengue Virus Capsid Protein Translocate Reversibly the Blood–Brain Barrier through a Receptor-Free Mechanism

Autori: Vera Neves, Frederico Aires-da-Silva, Maurício Morais, Lurdes Gano, Elisabete Ribeiro, Antónia Pinto, Sandra Aguiar, Diana Gaspar, Célia Fernandes, João D. G. Correia, Miguel A. R. B. Castanho
Pubblicato in: ACS Chemical Biology, Numero 12/5, 2017, Pagina/e 1257-1268, ISSN 1554-8929
Editore: American Chemical Society
DOI: 10.1021/acschembio.7b00087

Mechanisms of Vesicular Stomatitis Virus Inactivation by Protoporphyrin IX, Zinc-Protoporphyrin IX, and Mesoporphyrin IX

Autori: Christine Cruz-Oliveira, Andreza F. Almeida, João M. Freire, Marjolly B. Caruso, Maria A. Morando, Vivian N. S. Ferreira, Iranaia Assunção-Miranda, Andre M. O. Gomes, Miguel A. R. B. Castanho, Andrea T. Da Poian
Pubblicato in: Antimicrobial Agents and Chemotherapy, Numero 61/6, 2017, ISSN 0066-4804
Editore: American Society for Microbiology
DOI: 10.1128/aac.00053-17

Peptibodies: An elegant solution for a long-standing problem

Autori: Marco Cavaco, Miguel A. R. B. Castanho, Vera Neves
Pubblicato in: Peptide Science, Numero 110/1, 2018, Pagina/e e23095, ISSN 2475-8817
Editore: WILEY
DOI: 10.1002/bip.23095

Neuropeptide Kyotorphin Impacts on Lipopolysaccharide-Induced Glucocorticoid-Mediated Inflammatory Response. A Molecular Link to Nociception, Neuroprotection, and Anti-Inflammatory Action

Autori: Juliana Perazzo, Carla Lima, Montserrat Heras, Eduard Bardají, Mônica Lopes-Ferreira, Miguel Castanho
Pubblicato in: ACS Chemical Neuroscience, Numero 8/8, 2017, Pagina/e 1663-1667, ISSN 1948-7193
Editore: American Chemical Society
DOI: 10.1021/acschemneuro.7b00007

Pharmacological Potential of the Endogenous Dipeptide Kyotorphin and Selected Derivatives

Autori: Juliana Perazzo, Miguel A. R. B. Castanho, Sónia Sá Santos
Pubblicato in: Frontiers in Pharmacology, Numero 7, 2017, ISSN 1663-9812
Editore: Frontiers Media S.A.
DOI: 10.3389/fphar.2016.00530

Molecular determinants of the influenza fusion peptide activity

Autori: Diana Lousa, Antónia R.T. Pinto, Bruno L. Victor, Alessnadro Laio, Ana S. Veiga, Miguel A.R.B. Castanho, Cláudio M. Soares
Pubblicato in: Free Radical Biology and Medicine, Numero 120, 2018, Pagina/e S125, ISSN 0891-5849
Editore: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2018.04.413

Designing of Artificial Peptides for an Improved Antiviral Activity

Autori: Speranta Avram, Adina-Luminita Milac, Livia-Cristina Borcan, Dan Mihailescu, Florin Borcan, Miguel Castanho
Pubblicato in: Current Proteomics, Numero 15/4, 2018, Pagina/e 258-266, ISSN 1570-1646
Editore: Bentham Science Publishers
DOI: 10.2174/1570164615666180409151111

Quantitative analysis of molecular partition towards lipid membranes using surface plasmon resonance

Autori: Tiago N. Figueira, João M. Freire, Catarina Cunha-Santos, Montserrat Heras, João Gonçalves, Anne Moscona, Matteo Porotto, Ana Salomé Veiga, Miguel A. R. B. Castanho
Pubblicato in: Scientific Reports, Numero 7/1, 2017, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/srep45647

Challenging metastatic breast cancer with the natural defensin Pv D 1

Autori: Tiago N. Figueira, Filipa D. Oliveira, Inês Almeida, Érica O. Mello, Valdirene M. Gomes, Miguel A. R. B. Castanho, Diana Gaspar
Pubblicato in: Nanoscale, Numero 9/43, 2017, Pagina/e 16887-16899, ISSN 2040-3364
Editore: Royal Society of Chemistry
DOI: 10.1039/c7nr05872a

Motor unit number estimation (MUNE): Where are we now?

Autori: Mamede de Carvalho, Paul E. Barkhaus, Sanjeev D. Nandedkar, Michael Swash
Pubblicato in: Clinical Neurophysiology, Numero 129/8, 2018, Pagina/e 1507-1516, ISSN 1388-2457
Editore: Elsevier BV
DOI: 10.1016/j.clinph.2018.04.748

Prolongation of terminal latency of the phrenic nerve in amyotrophic lateral sclerosis – Is it clinically useful, and what are the mechanisms?

Autori: Mamede de Carvalho
Pubblicato in: Clinical Neurophysiology, Numero 128/10, 2017, Pagina/e 2094, ISSN 1388-2457
Editore: Elsevier BV
DOI: 10.1016/j.clinph.2017.07.404

Phrenic nerve stimulation is more sensitive than ultrasound measurement of diaphragm thickness in assessing early ALS progression

Autori: Susana Pinto, Pedro Alves, Michael Swash, Mamede de Carvalho
Pubblicato in: Neurophysiologie Clinique/Clinical Neurophysiology, Numero 47/1, 2017, Pagina/e 69-73, ISSN 0987-7053
Editore: Elsevier Masson
DOI: 10.1016/j.neucli.2016.08.001

Diaphragm motor responses to phrenic nerve stimulation in ALS: Surface and needle recordings

Autori: Mamede de Carvalho, Susana Pinto, Michael Swash
Pubblicato in: Clinical Neurophysiology, Numero 129/2, 2018, Pagina/e 349-353, ISSN 1388-2457
Editore: Elsevier BV
DOI: 10.1016/j.clinph.2017.11.019

Fasciculation in amyotrophic lateral sclerosis: origin and pathophysiological relevance

Autori: Mamede de Carvalho, Matthew C Kiernan, Michael Swash
Pubblicato in: Journal of Neurology, Neurosurgery & Psychiatry, Numero 88/9, 2017, Pagina/e 773-779, ISSN 0022-3050
Editore: BMJ Publishing Group
DOI: 10.1136/jnnp-2017-315574

Fasciculation: Does distance really matter?

Autori: Mamede de Carvalho
Pubblicato in: Clinical Neurophysiology, Numero 129/2, 2018, Pagina/e 462-463, ISSN 1388-2457
Editore: Elsevier BV
DOI: 10.1016/j.clinph.2017.11.021

Plasma level of club-cell (CC-16) predicts outcome in amyotrophic lateral sclerosis

Autori: A. C. Pronto-Laborinho, M. Gromicho, M. Pereira, S. Pinto, M. do A. Barros, M. Swash, M. de Carvalho
Pubblicato in: Acta Neurologica Scandinavica, Numero 137/2, 2018, Pagina/e 233-237, ISSN 0001-6314
Editore: Blackwell Publishing Inc.
DOI: 10.1111/ane.12851

Cramps and vinpocetine in ALS

Autori: Mamede de Carvalho
Pubblicato in: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Numero 19/1-2, 2017, Pagina/e 155-156, ISSN 2167-8421
Editore: Informa Healthcare
DOI: 10.1080/21678421.2017.1377735

Interplay of upper and lower motor neuron degeneration in amyotrophic lateral sclerosis

Autori: Mamede de Carvalho, Artiom Poliakov, Cristiano Tavares, Michael Swash
Pubblicato in: Clinical Neurophysiology, Numero 128/11, 2017, Pagina/e 2200-2204, ISSN 1388-2457
Editore: Elsevier BV
DOI: 10.1016/j.clinph.2017.08.024

International Survey of ALS Experts about Critical Questions for Assessing Patients with ALS

Autori: Mamede De Carvalho, Adam Ryczkowski, Peter Andersen, Marta Gromicho, Julian Grosskreutz, Magdalena Kuźma-Kozakiewicz, Susanne Petri, Maria Piotrkiewicz, Gabriel Miltenberger Miltenyi
Pubblicato in: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Numero 18/7-8, 2017, Pagina/e 505-510, ISSN 2167-8421
Editore: Informa Healthcare
DOI: 10.1080/21678421.2017.1349150

Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies

Autori: Hugo Vicente Miranda, Éva M. Szegő, Luís M. A. Oliveira, Carlo Breda, Ekrem Darendelioglu, Rita M. de Oliveira, Diana G. Ferreira, Marcos A. Gomes, Ruth Rott, Márcia Oliveira, Francesca Munari, Francisco J. Enguita, Tânia Simões, Eva F. Rodrigues, Michael Heinrich, Ivo C. Martins, Irina Zamolo, Olaf Riess, Carlos Cordeiro, Ana Ponces-Freire, Hilal A. Lashuel, Nuno C. Santos, Luisa V. Lopes,
Pubblicato in: Brain, Numero 140/5, 2017, Pagina/e 1399-1419, ISSN 0006-8950
Editore: Oxford University Press
DOI: 10.1093/brain/awx056

α-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B

Autori: Diana G Ferreira, Mariana Temido-Ferreira, Hugo Vicente Miranda, Vânia L Batalha, Joana E Coelho, Éva M Szegö, Inês Marques-Morgado, Sandra H Vaz, Jeong Seop Rhee, Matthias Schmitz, Inga Zerr, Luísa V Lopes, Tiago F Outeiro
Pubblicato in: Nature Neuroscience, Numero 20/11, 2017, Pagina/e 1569-1579, ISSN 1097-6256
Editore: Nature Publishing Group
DOI: 10.1038/nn.4648

Adenosine A 2A Receptors Modulate α-Synuclein Aggregation and Toxicity

Autori: Diana G. Ferreira, Vânia L. Batalha, Hugo Vicente Miranda, Joana E. Coelho, Rui Gomes, Francisco Q. Gonçalves, Joana I. Real, José Rino, António Albino-Teixeira, Rodrigo A. Cunha, Tiago F. Outeiro, Luísa V. Lopes
Pubblicato in: Cerebral Cortex, 2017, Pagina/e bhv268, ISSN 1047-3211
Editore: Oxford University Press
DOI: 10.1093/cercor/bhv268

Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca2+]i overload and NF-κB activation

Autori: Nadia A. Rivero-Segura, Edgar Flores-Soto, Selene García de la Cadena, Isabel Coronado-Mares, Juan C. Gomez-Verjan, Diana G. Ferreira, Erika Alejandra Cabrera-Reyes, Luísa V. Lopes, Lourdes Massieu, Marco Cerbón
Pubblicato in: PLOS ONE, Numero 12/5, 2017, Pagina/e e0176910, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0176910

Mutant A53T α-Synuclein Improves Rotarod Performance Before Motor Deficits and Affects Metabolic Pathways

Autori: Patrícia S. Guerreiro, Joana E. Coelho, Inês Sousa-Lima, Paula Macedo, Luísa V. Lopes, Tiago F. Outeiro, Teresa F. Pais
Pubblicato in: NeuroMolecular Medicine, Numero 19/1, 2017, Pagina/e 113-121, ISSN 1535-1084
Editore: Humana Press, Inc.
DOI: 10.1007/s12017-016-8435-5

Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease

Autori: Emilie Faivre, Joana E. Coelho, Katja Zornbach, Enas Malik, Younis Baqi, Marion Schneider, Lucrezia Cellai, Kevin Carvalho, Shéhérazade Sebda, Martin Figeac, Sabiha Eddarkaoui, Raphaëlle Caillierez, Yijuang Chern, Michael Heneka, Nicolas Sergeant, Christa E. Müller, Annett Halle, Luc Buée, Luisa V. Lopes, David Blum
Pubblicato in: Frontiers in Molecular Neuroscience, Numero 11, 2018, ISSN 1662-5099
Editore: Frontiers Research Foundation
DOI: 10.3389/fnmol.2018.00235

Thrombolysis and thrombectomy in patients treated with dabigatran with acute ischemic stroke: Expert opinion

Autori: HC Diener, R Bernstein, K Butcher, B Campbell, G Cloud, A Davalos, S Davis, JM Ferro, M Grond, D Krieger, G Ntaios, A Slowik, E Touzé
Pubblicato in: International Journal of Stroke, Numero 12/1, 2016, Pagina/e 9-12, ISSN 1747-4930
Editore: Blackwell
DOI: 10.1177/1747493016669849

European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis - endorsed by the European Academy of Neurology

Autori: J. M. Ferro, M.-G. Bousser, P. Canhão, J. M. Coutinho, I. Crassard, F. Dentali, M. di Minno, A. Maino, I. Martinelli, F. Masuhr, D. Aguiar de Sousa, J. Stam
Pubblicato in: European Journal of Neurology, Numero 24/10, 2017, Pagina/e 1203-1213, ISSN 1351-5101
Editore: Blackwell Publishing Inc.
DOI: 10.1111/ene.13381

Cerebral venous thrombosis

Autori: Suzanne M. Silvis, Diana Aguiar de Sousa, José M. Ferro, Jonathan M Coutinho
Pubblicato in: Nature Reviews Neurology, Numero 13/9, 2017, Pagina/e 555-565, ISSN 1759-4758
Editore: Nature Publishing Group
DOI: 10.1038/nrneurol.2017.104

Safety of Pregnancy After Cerebral Venous Thrombosis

Autori: Diana Aguiar de Sousa, Patrícia Canhão, Isabelle Crassard, Jonathan Coutinho, Antonio Arauz, Adriana Conforto, Yannick Béjot, Maurice Giroud, José M. Ferro, Teresa Pinho e Melo, Liliana Pereira, Elisa Costa, Miguel Rodrigues, Miguel Viana Baptista, Marta Carvalho, Gabriela Lopes, Manuel Correia, Ana Amélia Pinto, Paulo Coelho, Luís Cunha, Andreia Veiga, Mário Silva, Maria Manuela Costa, Hip
Pubblicato in: Stroke, Numero 48/11, 2017, Pagina/e 3130-3133, ISSN 0039-2499
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.117.018829

Post-stroke seizures are clinically underestimated

Autori: Carla Bentes, Hugo Martins, Ana Rita Peralta, Carlos Casimiro, Carlos Morgado, Ana Catarina Franco, Ana Catarina Fonseca, Ruth Geraldes, Patrícia Canhão, Teresa Pinho e Melo, Teresa Paiva, José M. Ferro
Pubblicato in: Journal of Neurology, Numero 264/9, 2017, Pagina/e 1978-1985, ISSN 0340-5354
Editore: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00415-017-8586-9

Five-Year Risk of Stroke after TIA or Minor Ischemic Stroke

Autori: Pierre Amarenco, Philippa C. Lavallée, Linsay Monteiro Tavares, Julien Labreuche, Gregory W. Albers, Halim Abboud, Sabrina Anticoli, Heinrich Audebert, Natan M. Bornstein, Louis R. Caplan, Manuel Correia, Geoffrey A. Donnan, José M. Ferro, Fernando Gongora-Rivera, Wolfgang Heide, Michael G. Hennerici, Peter J. Kelly, Michal Král, Hsiu-Fen Lin, Carlos Molina, Jong Moo Park, Francisco Purroy, Pet
Pubblicato in: New England Journal of Medicine, Numero 378/23, 2018, Pagina/e 2182-2190, ISSN 0028-4793
Editore: Massachusetts Medical Society
DOI: 10.1056/nejmoa1802712

European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis – Endorsed by the European Academy of Neurology

Autori: José M Ferro, Marie-Germaine Bousser, Patrícia Canhão, Jonathan M Coutinho, Isabelle Crassard, Francesco Dentali, Matteo di Minno, Alberto Maino, Ida Martinelli, Florian Masuhr, Diana Aguiar de Sousa, Jan Stam
Pubblicato in: European Stroke Journal, Numero 2/3, 2017, Pagina/e 195-221, ISSN 2396-9873
Editore: SAGE PUBLICATIONS LTD
DOI: 10.1177/2396987317719364

Epileptic manifestations in stroke patients treated with intravenous alteplase

Autori: C. Bentes, H. Martins, A. R. Peralta, C. Morgado, C. Casimiro, A. C. Franco, A. C. Fonseca, R. Geraldes, P. Canhão, T. Pinho e Melo, T. Paiva, J. M. Ferro
Pubblicato in: European Journal of Neurology, Numero 24/6, 2017, Pagina/e 755-761, ISSN 1351-5101
Editore: Blackwell Publishing Inc.
DOI: 10.1111/ene.13292

Differences in Characteristics and Outcomes Between Asian and Non-Asian Patients in the TIAregistry.org

Autori: Takao Hoshino, Shinichiro Uchiyama, Lawrence K.S. Wong, Leila Sissani, Gregory W. Albers, Natan M. Bornstein, Louis R. Caplan, Geoffrey A. Donnan, José M. Ferro, Michael G. Hennerici, Julien Labreuche, Philippa C. Lavallée, Carlos Molina, Peter M. Rothwell, Philippe Gabriel Steg, Pierre-Jean Touboul, Éric Vicaut, Pierre Amarenco
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Symptomatic Patients Remain at Substantial Risk of Arterial Disease Complications Before and After Endarterectomy or Stenting

Autori: Cristina Hobeanu, Philippa C. Lavallée, Peter M. Rothwell, Leila Sissani, Gregory W. Albers, Natan M. Bornstein, Louis R. Caplan, Geoffrey A. Donnan, José M. Ferro, Michael G. Hennerici, Julien Labreuche, Carlos Molina, Philippe Gabriel Steg, Pierre-Jean Touboul, Shinichiro Uchiyama, Éric Vicaut, Lawrence K.S. Wong, Pierre Amarenco
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Patients With Undetermined Stroke Have Increased Atrial Fibrosis

Autori: Ana Catarina Fonseca, Pedro Alves, Nuno Inácio, João Pedro Marto, Miguel Viana-Baptista, Teresa Pinho-e-Melo, José M. Ferro, Ana G. Almeida
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Increase in the Admission of Stroke Mimics after Change in Emergency Shifts

Autori: Mariana Vargas, Mariana Costa, Teresa Pinho e Melo, José M. Ferro, Ana Catarina Fonseca
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Patent foramen ovale and stroke

Autori: Bruno Miranda, Ana Catarina Fonseca, José M. Ferro
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Quantitative EEG and functional outcome following acute ischemic stroke

Autori: Carla Bentes, Ana Rita Peralta, Pedro Viana, Hugo Martins, Carlos Morgado, Carlos Casimiro, Ana Catarina Franco, Ana Catarina Fonseca, Ruth Geraldes, Patrícia Canhão, Teresa Pinho e Melo, Teresa Paiva, José M. Ferro
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Frequency of post-stroke electroencephalographic epileptiform activity – a systematic review and meta-analysis of observational studies

Autori: Carla Bentes, Filipe B Rodrigues, Diana Sousa, Gonçalo S Duarte, Ana C Franco, Raquel Marques, Hipólito Nzwalo, Ana R Peralta, José M Ferro, João Costa
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Safety of pregnancy after cerebral venous thrombosis: systematic review update

Autori: Diana Aguiar de Sousa, Patrícia Canhão, José M. Ferro
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Recanalization in Cerebral Venous Thrombosis

Autori: Diana Aguiar de Sousa, Lia Lucas Neto, Patrícia Canhão, José M. Ferro
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The impact of anger in adherence to treatment and beliefs about disease 1 year after stroke

Autori: A. Catarina Santos, José M. Ferro
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Can We Predict Who Will Develop Hypertension After Carotid Endarterectomy?

Autori: José M. Ferro
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Patients with undetermined ischemic stroke etiology show a high percentage of atrial tissue fibrosis

Autori: A.C. Fonseca, P. Nascimento, T. Pinho e Melo, P. Canhão, J.M. Ferro, A.G. Almeida
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Epilepsia partialis continua after an anterior circulation ischaemic stroke

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Validation of a Lower Back “Wearable”-Based Sit-to-Stand and Stand-to-Sit Algorithm for Patients With Parkinson's Disease and Older Adults in a Home-Like Environment

Autori: Minh H. Pham, Elke Warmerdam, Morad Elshehabi, Christian Schlenstedt, Lu-Marie Bergeest, Maren Heller, Linda Haertner, Joaquim J. Ferreira, Daniela Berg, Gerhard Schmidt, Clint Hansen, Walter Maetzler
Pubblicato in: Frontiers in Neurology, Numero 9, 2018, ISSN 1664-2295
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Opicapone for the management of end-of-dose motor fluctuations in patients with Parkinson’s disease treated with L-DOPA

Autori: Andrew J. Lees, Joaquim Ferreira, Olivier Rascol, Heinz Reichmann, Fabrizio Stocchi, Eduardo Tolosa, Werner Poewe
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Physician perception versus true efficacy of tetrabenazine for Huntington’s disease

Autori: Filipe B. Rodrigues, Joaquim J. Ferreira, Edward J. Wild
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Autori: G. Tamás, C. Abrantes, A. Valadas, P. Radics, A. Albanese, M. A. J. Tijssen, J. J. Ferreira
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Erratum - Information Sources and Decision-Making in Neurosurgery: Results of a Survey of Members of the Brazilian Neurosurgery Society

Autori: Rodrigo Gorayeb, Maria Forjaz, Antônio Gonçalves-Ferreira, Joaquim Ferreira
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Information Sources and Decision-Making in Neurosurgery: Results of a Survey of Members of the Brazilian Neurosurgery Society

Autori: Rodrigo Gorayeb, Maria João Forjaz, Antônio Gonçalves-Ferreira, Joaquim Ferreira
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Editore: GEORG THIEME VERLAG KG
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Psychosocial impact of Parkinson's disease-associated dysarthria: Cross-cultural adaptation and validation of the Dysarthria Impact Profile into European Portuguese

Autori: Rita Cardoso, Isabel Guimarães, Helena Santos, Rita Loureiro, Josefa Domingos, Daisy Abreu, Nilza Gonçalves, Serge Pinto, Joaquim J Ferreira
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Comments on: ‘Pyridostigmine bromide versus fludrocortisone in the treatment of orthostatic hypotension in Parkinson's disease - a randomized controlled trial’

Autori: R. M. Simões, A. Castro Caldas, J. J. Ferreira
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Suspected adverse drug reaction reports with oral anticoagulants in Portugal: a pharmacovigilance study

Autori: Daniel Caldeira, Raquel Rodrigues, Daisy Abreu, Ana Marta Anes, Mário M. Rosa, Joaquim J. Ferreira
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The launch of opicapone for Parkinson’s disease: negatives versus positives

Autori: Ana Castro Caldas, Tiago Teodoro, Joaquim J Ferreira
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Mitochondrial quality control pathways: PINK1 acts as a gatekeeper

Autori: Elvira P. Leites, Vanessa A. Morais
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β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog–Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models

Autori: Thomas Goiran, Eric Duplan, Mounia Chami, Alexandre Bourgeois, Wejdane El Manaa, Lila Rouland, Julie Dunys, Inger Lauritzen, Han You, Vuk Stambolic, Maria-Grazia Biféri, Martine Barkats, Sanjay W. Pimplikar, Nicolas Sergeant, Morvane Colin, Vanessa A. Morais, Raphaelle Pardossi-Piquard, Frédéric Checler, Cristine Alves da Costa
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Cardiolipin promotes electron transport between ubiquinone and complex I to rescue PINK1 deficiency

Autori: Melissa Vos, Ann Geens, Claudia Böhm, Liesbeth Deaulmerie, Jef Swerts, Matteo Rossi, Katleen Craessaerts, Elvira P. Leites, Philip Seibler, Aleksandar Rakovic, Thora Lohnau, Bart De Strooper, Sarah-Maria Fendt, Vanessa A. Morais, Christine Klein, Patrik Verstreken
Pubblicato in: The Journal of Cell Biology, Numero 216/3, 2017, Pagina/e 695-708, ISSN 0021-9525
Editore: Rockefeller University Press
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Chronic, intermittent treatment with a cannabinoid receptor agonist impairs recognition memory and brain network functional connectivity

Autori: Francisco M. Mouro, Joaquim A. Ribeiro, Ana M. Sebastião, Neil Dawson
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Amyotrophic Lateral Sclerosis (ALS) and Adenosine Receptors

Autori: Ana M. Sebastião, Nádia Rei, Joaquim A. Ribeiro
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Autophagy induction impairs Wnt/β-catenin signalling through β-catenin relocalisation in glioblastoma cells

Autori: Barbara Colella, Fiorella Faienza, Marianna Carinci, Giuseppina D'Alessandro, Myriam Catalano, Antonio Santoro, Francesco Cecconi, Cristina Limatola, Sabrina Di Bartolomeo
Pubblicato in: Cellular Signalling, Numero 53, 2019, Pagina/e 357-364, ISSN 0898-6568
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Kv1.3 activity perturbs the homeostatic properties of astrocytes in glioma

Autori: Alfonso Grimaldi, Giuseppina D’Alessandro, Maria Amalia Di Castro, Clotilde Lauro, Vikrant Singh, Francesca Pagani, Luigi Sforna, Francesca Grassi, Silvia Di Angelantonio, Luigi Catacuzzeno, Heike Wulff, Cristina Limatola, Myriam Catalano
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Decreased plasma C-reactive protein levels in APOE ε 4 allele carriers

Autori: Henna Martiskainen, Mari Takalo, Alina Solomon, Alena Stančáková, Mikael Marttinen, Teemu Natunen, Annakaisa Haapasalo, Sanna-Kaisa Herukka, Johanna Kuusisto, Hilkka Soininen, Miia Kivipelto, Markku Laakso, Mikko Hiltunen
Pubblicato in: Annals of Clinical and Translational Neurology, Numero 5/10, 2018, Pagina/e 1229-1240, ISSN 2328-9503
Editore: WILEY
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CXCL16/CXCR6 Axis Drives Microglia/Macrophages Phenotype in Physiological Conditions and Plays a Crucial Role in Glioma

Autori: Francesca Lepore, Giuseppina D'Alessandro, Fabrizio Antonangeli, Antonio Santoro, Vincenzo Esposito, Cristina Limatola, Flavia Trettel
Pubblicato in: Frontiers in Immunology, Numero 9, 2018, ISSN 1664-3224
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Inflammation, neurodegeneration and protein aggregation in the retina as ocular biomarkers for Alzheimer’s disease in the 3xTg-AD mouse model

Autori: Alfonso Grimaldi, Carlo Brighi, Giovanna Peruzzi, Davide Ragozzino, Valentina Bonanni, Cristina Limatola, Giancarlo Ruocco, Silvia Di Angelantonio
Pubblicato in: Cell Death & Disease, Numero 9/6, 2018, ISSN 2041-4889
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Ca2+-activated K+ channels modulate microglia affecting motor neuron survival in hSOD1G93A mice

Autori: Germana Cocozza, Maria Amalia di Castro, Laura Carbonari, Alfonso Grimaldi, Fabrizio Antonangeli, Stefano Garofalo, Alessandra Porzia, Michele Madonna, Fabrizio Mainiero, Angela Santoni, Francesca Grassi, Heike Wulff, Giuseppina D'Alessandro, Cristina Limatola
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TrkB-ICD Fragment, Originating From BDNF Receptor Cleavage, Is Translocated to Cell Nucleus and Phosphorylates Nuclear and Axonal Proteins

Autori: João Fonseca-Gomes, André Jerónimo-Santos, Angelina Lesnikova, Plinio Casarotto, Eero Castrén, Ana M. Sebastião, Maria J. Diógenes
Pubblicato in: Frontiers in Molecular Neuroscience, Numero 12, 2019, ISSN 1662-5099
Editore: Frontiers Research Foundation
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Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice

Autori: Sami Gabbouj, Teemu Natunen, Hennariikka Koivisto, Kimmo Jokivarsi, Mari Takalo, Mikael Marttinen, Rebekka Wittrahm, Susanna Kemppainen, Reyhaneh Naderi, Adrián Posado-Fernández, Simo Ryhänen, Petra Mäkinen, Kaisa M.A. Paldanius, Gonçalo Doria, Pekka Poutiainen, Orfeu Flores, Annakaisa Haapasalo, Heikki Tanila, Mikko Hiltunen
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A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology

Autori: Mikael Marttinen, Jussi Paananen, Antonio Neme, Vikram Mitra, Mari Takalo, Teemu Natunen, Kaisa M.A. Paldanius, Petra Mäkinen, Michael Bremang, Mitja I. Kurki, Tuomas Rauramaa, Ville Leinonen, Hilkka Soininen, Annakaisa Haapasalo, Ian Pike, Mikko Hiltunen
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Adenosine A 2A receptors facilitate synaptic NMDA currents in CA1 pyramidal neurons

Autori: Francisco M Mouro, Diogo M Rombo, Raquel B Dias, Joaquim A Ribeiro, Ana M Sebastião
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Brain-Derived Neurotrophic Factor (BDNF) Role in Cannabinoid-Mediated Neurogenesis

Autori: Filipa Fiel Ferreira, Filipa F. Ribeiro, Rui S. Rodrigues, Ana Maria Sebastião, Sara Xapelli
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Anxiety Assessment in Pre-clinical Tests and in Clinical Trials: A Critical Review

Autori: Lígia Castanheira, Miguel F. Ferreira, Ana M. Sebastião, Diogo Telles-Correia
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Depression Assessment in Clinical Trials and Pre-clinical Tests: A Critical Review

Autori: Miguel F. Ferreira, Lígia Castanheira, Ana M. Sebastião, Diogo Telles-Correia
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Hippocampal GABAergic transmission: a new target for adenosine control of excitability

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Rare Variants in PLD3 Do Not Affect Risk for Early-Onset Alzheimer Disease in a European Consortium Cohort

Autori: Rita Cacace, Tobi Van den Bossche, Sebastiaan Engelborghs, Nathalie Geerts, Annelies Laureys, Lubina Dillen, Caroline Graff, Håkan Thonberg, Huei-Hsin Chiang, Pau Pastor, Sara Ortega-Cubero, Maria A. Pastor, Janine Diehl-Schmid, Panagiotis Alexopoulos, Luisa Benussi, Roberta Ghidoni, Giuliano Binetti, Benedetta Nacmias, Sandro Sorbi, Raquel Sanchez-Valle, Albert Lladó, Ellen Gelpi, Maria Rosário Almeida, Isabel Santana, Magda Tsolaki, Maria Koutroumani, Jordi Clarimon, Alberto Lleó, Juan Fortea, Alexandre de Mendonça, Madalena Martins, Barbara Borroni, Alessandro Padovani, Radoslav Matej, Zdenek Rohan, Mathieu Vandenbulcke, Rik Vandenberghe, Peter P. De Deyn, Patrick Cras, Julie van der Zee, Kristel Sleegers, Christine Van Broeckhoven
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BDNF, via truncated TrkB receptor, modulates GlyT1 and GlyT2 in astrocytes

Autori: Rita I. Aroeira, Ana M. Sebastião, Cláudia A. Valente
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Adenosine A2A receptor activation is determinant for BDNF actions upon GABA and glutamate release from rat hippocampal synaptosomes

Autori: Sandra Henriques Vaz, Sofia Rapaz Lérias, Sara Parreira, Maria José Diógenes, Ana Maria Sebastião
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Do We Have a Channel Solution for ALS?

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Tracking motor neuron loss in a set of six muscles in amyotrophic lateral sclerosis using the Motor Unit Number Index (MUNIX): a 15-month longitudinal multicentre trial

Autori: Christoph Neuwirth, Paul E Barkhaus, Christian Burkhardt, José Castro, David Czell, Mamede de Carvalho, Sanjeev Nandedkar, Erik Stålberg, Markus Weber
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Presymptomatic and symptomatic ALS SOD1(G93A) mice differ in adenosine A1 and A2A receptor-mediated tonic modulation of neuromuscular transmission

Autori: Filipe Nascimento, Ana M. Sebastião, Joaquim A. Ribeiro
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Neuromodulation and metamodulation by adenosine: Impact and subtleties upon synaptic plasticity regulation

Autori: Ana M. Sebastião, Joaquim A. Ribeiro
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Prognostic models based on patient snapshots and time windows: Predicting disease progression to assisted ventilation in Amyotrophic Lateral Sclerosis

Autori: André V. Carreiro, Pedro M.T. Amaral, Susana Pinto, Pedro Tomás, Mamede de Carvalho, Sara C. Madeira
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Brain-derived neurotrophic factor mediates neuroprotection against A β -induced toxicity through a mechanism independent on adenosine 2A receptor activation

Autori: André Jerónimo-Santos, João Fonseca-Gomes, Diogo Andrade Guimarães, Sara Ramalho Tanqueiro, Rita Mira Ramalho, Joaquim Alexandre Ribeiro, Ana Maria Sebastião, Maria José Diógenes
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Integrative biomarker discovery in neurodegenerative diseases

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Decrease in APP and CP mRNA expression supports impairment of iron export in Alzheimer's disease patients

Autori: Cláudia Guerreiro, Bruno Silva, Ângela C. Crespo, Liliana Marques, Sónia Costa, Ângela Timóteo, Erica Marcelino, Carolina Maruta, Arminda Vilares, Mafalda Matos, Frederico Simões Couto, Paula Faustino, Ana Verdelho, Manuela Guerreiro, Ana Herrero, Cristina Costa, Alexandre de Mendonça, Madalena Martins, Luciana Costa
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Purine nucleosides in neuroregeneration and neuroprotection

Autori: Filipa F. Ribeiro, Sara Xapelli, Catarina Miranda-Lourenço, Sara R. Tanqueiro, João Fonseca-Gomes, Maria J. Diógenes, Joaquim A. Ribeiro, Ana M. Sebastião
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Neural commitment of human pluripotent stem cells under defined conditions recapitulates neural development and generates patient-specific neural cells

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Adenosine A2A Receptors Modulate α-Synuclein Aggregation and Toxicity

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Editore: Oxford Journals

Dysregulation of TrkB Receptors and BDNF Function by Amyloid-β Peptide is Mediated by Calpain

Autori: André Jerónimo-Santos, Sandra Henriques Vaz, Sara Parreira, Sofia Rapaz-Lérias, António P. Caetano, Valérie Buée-Scherrer, Eero Castrén, Claudia A. Valente, David Blum, Ana Maria Sebastião, Maria José Diógenes
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Axonal elongation and dendritic branching is enhanced by adenosine A2A receptors activation in cerebral cortical neurons

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Predicting clinical response in people at ultra-high risk of psychosis: a systematic and quantitative review

Autori: Andrea Mechelli, Diana Prata, Charles Kefford, Shitij Kapur
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Comment on: The Awaji criteria are not always superior to the previous criteria: A meta-analysis

Autori: Mamede de Carvalho, João Costa, Michael Swash
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Ensuring continued progress in biomarkers for amyotrophic lateral sclerosis: Another view

Autori: Mamede de Carvalho
Pubblicato in: Muscle & Nerve, Numero 0148639X, 2015, Pagina/e 460-461, ISSN 0148-639X
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The R of ALSFRS-R: Does it really mirror functional respiratory involvement in amyotrophic lateral sclerosis?

Autori: Susana Pinto, Mamede de Carvalho
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Editore: Informa Healthcare
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The giant miniature endplate potentials frequency is increased in aged rats

Autori: Paula A. Pousinha, Alexandra M. Correia, Ana M. Sebastião, Joaquim A. Ribeiro
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Tackling diagnostic delays in ALS

Autori: Mamede de Carvalho
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Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

Autori: Axel Freischmidt, Thomas Wieland, Benjamin Richter, Wolfgang Ruf, Veronique Schaeffer, Kathrin Müller, Nicolai Marroquin, Frida Nordin, Annemarie Hübers, Patrick Weydt, Susana Pinto, Rayomond Press, Stéphanie Millecamps, Nicolas Molko, Emilien Bernard, Claude Desnuelle, Marie-Hélène Soriani, Johannes Dorst, Elisabeth Graf, Ulrika Nordström, Marisa S Feiler, Stefan Putz, Tobias M Boeckers, Thomas Meyer, Andrea S Winkler, Juliane Winkelman, Mamede de Carvalho, Dietmar R Thal, Markus Otto, Thomas Brännström, Alexander E Volk, Petri Kursula, Karin M Danzer, Peter Lichtner, Ivan Dikic, Thomas Meitinger, Albert C Ludolph, Tim M Strom, Peter M Andersen, Jochen H Weishaupt
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Changes in corticostriatal connectivity during reinforcement learning in humans

Autori: Guillermo Horga, Tiago V. Maia, Rachel Marsh, Xuejun Hao, Dongrong Xu, Yunsuo Duan, Gregory Z. Tau, Barbara Graniello, Zhishun Wang, Alayar Kangarlu, Diana Martinez, Mark G. Packard, Bradley S. Peterson
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MicroRNA-34a Modulates Neural Stem Cell Differentiation by Regulating Expression of Synaptic and Autophagic Proteins

Autori: Ana L. Morgado, Joana M. Xavier, Pedro A. Dionísio, Maria F. C. Ribeiro, Raquel B. Dias, Ana M. Sebastião, Susana Solá, Cecília M. P. Rodrigues
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Synaptic mechanisms of adenosine A 2A receptor-mediated hyperexcitability in the hippocampus

Autori: Diogo M. Rombo, Kathryn Newton, Wiebke Nissen, Sylvia Badurek, Jacqueline M. Horn, Liliana Minichiello, John G.R. Jefferys, Ana M. Sebastiao, Karri P. Lamsa
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The Combined Inhibitory Effect of the Adenosine A 1 and Cannabinoid CB 1 Receptors on cAMP Accumulation in the Hippocampus Is Additive and Independent of A 1 Receptor Desensitization

Autori: André Serpa, Sara Correia, Joaquim A. Ribeiro, Ana M. Sebastião, José F. Cascalheira
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Non-literal language deficits in mild cognitive impairment

Autori: Sandra Cardoso, Dina Silva, João Maroco, Alexandre de Mendonça, Manuela Guerreiro
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Neuroinflammation after neonatal hypoxia–ischemia is associated with alterations in the purinergic system: adenosine deaminase 1 isoenzyme is the most predominant after insult

Autori: Victor Camera Pimentel, Maria Beatriz Moretto, Mariana Colino Oliveira, Daniela Zanini, Ana Maria Sebastião, Maria Rosa Chitolina Schetinger
Pubblicato in: Molecular and Cellular Biochemistry, Numero 03008177, 2015, Pagina/e 169-177, ISSN 0300-8177
Editore: Kluwer Academic/Plenum Publishers
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Genetic variability in SQSTM1 and risk of early-onset Alzheimer dementia: a European early-onset dementia consortium study

Autori: Elise Cuyvers, Julie van der Zee, Karolien Bettens, Sebastiaan Engelborghs, Mathieu Vandenbulcke, Caroline Robberecht, Lubina Dillen, Céline Merlin, Nathalie Geerts, Caroline Graff, Håkan Thonberg, Huei-Hsin Chiang, Pau Pastor, Sara Ortega-Cubero, Maria A. Pastor, Janine Diehl-Schmid, Panagiotis Alexopoulos, Luisa Benussi, Roberta Ghidoni, Giuliano Binetti, Benedetta Nacmias, Sandro Sorbi, Raquel Sanchez-Valle, Albert Lladó, Ellen Gelpi, Maria Rosário Almeida, Isabel Santana, Jordi Clarimon, Alberto Lleó, Juan Fortea, Alexandre de Mendonça, Madalena Martins, Barbara Borroni, Alessandro Padovani, Radoslav Matěj, Zdenek Rohan, Agustín Ruiz, Giovanni B. Frisoni, Gian Maria Fabrizi, Rik Vandenberghe, Peter P. De Deyn, Christine Van Broeckhoven, Kristel Sleegers
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Prevalence and prognosis of Alzheimer’s disease at the mild cognitive impairment stage

Autori: Stephanie J. B. Vos, Frans Verhey, Lutz Frölich, Johannes Kornhuber, Jens Wiltfang, Wolfgang Maier, Oliver Peters, Eckart Rüther, Flavio Nobili, Silvia Morbelli, Giovanni B. Frisoni, Alexander Drzezga, Mira Didic, Bart N. M. van Berckel, Andrew Simmons, Hilkka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Simon Lovestone, Cristina Muscio, Sanna-Kaisa Herukka, Eric Salmon, Christine Bastin, Anders Wallin, Arto Nordlund, Alexandre de Mendonça, Dina Silva, Isabel Santana, Raquel Lemos, Sebastiaan Engelborghs, Stefan Van der Mussele, Yvonne Freund-Levi, Åsa K. Wallin, Harald Hampel, Wiesje van der Flier, Philip Scheltens, Pieter Jelle Visser
Pubblicato in: Brain, Numero 00068950, 2015, Pagina/e 1327-1338, ISSN 0006-8950
Editore: Oxford University Press
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Phosphoneurofilament heavy chain and N-glycomics from the cerebrospinal fluid in amyotrophic lateral sclerosis

Autori: Margarida Gonçalves, Linda Tillack, Mamede de Carvalho, Susana Pinto, Harald S. Conradt, Júlia Costa
Pubblicato in: Clinica Chimica Acta, Numero 00098981, 2015, Pagina/e 342-349, ISSN 0009-8981
Editore: Elsevier BV
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Ultrasound in ALS: Is it a sound method?

Autori: Mamede de Carvalho
Pubblicato in: Clinical Neurophysiology, Numero 13882457, 2015, Pagina/e 651-652, ISSN 1388-2457
Editore: Elsevier BV
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Differential Role of the Proteasome in the Early and Late Phases of BDNF-Induced Facilitation of LTP

Autori: A. R. Santos, M. Mele, S. H. Vaz, B. Kellermayer, M. Grimaldi, M. Colino-Oliveira, D. M. Rombo, D. Comprido, A. M. Sebastiao, C. B. Duarte
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Editore: Society for Neuroscience
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Classification of primary progressive aphasia: Do unsupervised data mining methods support a logopenic variant?

Autori: Carolina Maruta, Telma Pereira, Sara C. Madeira, Alexandre De Mendonça, Manuela Guerreiro
Pubblicato in: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Numero 21678421, 2015, Pagina/e 147-159, ISSN 2167-8421
Editore: Informa Healthcare
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The use of biomarkers for the etiologic diagnosis of MCI in Europe: An EADC survey

Autori: Martina Bocchetta, Samantha Galluzzi, Patrick Gavin Kehoe, Eduardo Aguera, Roberto Bernabei, Roger Bullock, Mathieu Ceccaldi, Jean-François Dartigues, Alexandre de Mendonça, Mira Didic, Maria Eriksdotter, Olivier Félician, Lutz Frölich, Hermann-Josef Gertz, Merja Hallikainen, Steen G. Hasselbalch, Lucrezia Hausner, Isabell Heuser, Frank Jessen, Roy W. Jones, Alexander Kurz, Brian Lawlor, Alberto Lleo, Pablo Martinez-Lage, Patrizia Mecocci, Shima Mehrabian, Andreas Monsch, Flavio Nobili, Agneta Nordberg, Marcel Olde Rikkert, Jean-Marc Orgogozo, Florence Pasquier, Oliver Peters, Eric Salmon, Carmen Sánchez-Castellano, Isabel Santana, Marie Sarazin, Latchezar Traykov, Magda Tsolaki, Pieter Jelle Visser, Åsa K. Wallin, Gordon Wilcock, David Wilkinson, Henrike Wolf, Görsev Yener, Dina Zekry, Giovanni B. Frisoni
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Editore: Elsevier BV
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Significance of Subjective Memory Complaints in the Clinical Setting

Autori: D. Silva, M. Guerreiro, C. Faria, J. Maroco, B. A. Schmand, A. d. Mendonca
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Modulation of cGMP accumulation by adenosine A1 receptors at the hippocampus: Influence of cGMP levels and gender

Autori: André Serpa, Ana M. Sebastião, José F. Cascalheira
Pubblicato in: European Journal of Pharmacology, Numero 00142999, 2014, Pagina/e 83-90, ISSN 0014-2999
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Endogenous inhibition of hippocampal LTD and depotentiation by vasoactive intestinal peptide VPAC 1 receptors

Autori: Diana Cunha-Reis, Maria de Fatima Aidil-Carvalho, Joaquim A. Ribeiro
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Young slow-progressing ALS patients are at higher risk of inappropriate and disease-quickening surgeries

Autori: Susana Pinto, Mamede de Carvalho
Pubblicato in: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Numero 21678421, 2014, Pagina/e 621-621, ISSN 2167-8421
Editore: Informa Healthcare
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Maternal separation impairs long term-potentiation in CA1-CA3 synapses and hippocampal-dependent memory in old rats

Autori: Vasco C. Sousa, Joana Vital, Ana Rita Costenla, Vânia L. Batalha, Ana M. Sebastião, Joaquim A. Ribeiro, Luísa V. Lopes
Pubblicato in: Neurobiology of Aging, Numero 01974580, 2014, Pagina/e 1680-1685, ISSN 0197-4580
Editore: Elsevier BV
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Does surgery accelerate progression of amyotrophic lateral sclerosis?

Autori: S. Pinto, M. Swash, M. de Carvalho
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Editore: BMJ Publishing Group
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Adenosine A2A Receptors Activation Facilitates Neuromuscular Transmission in the Pre-Symptomatic Phase of the SOD1(G93A) ALS Mice, but Not in the Symptomatic Phase

Autori: Filipe Nascimento, Paula A. Pousinha, Alexandra M. Correia, Rui Gomes, Ana M. Sebastião, Joaquim A. Ribeiro
Pubblicato in: PLoS ONE, Numero 19326203, 2014, Pagina/e e104081, ISSN 1932-6203
Editore: Public Library of Science
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Impact of in vivo chronic blockade of adenosine A2A receptors on the BDNF-mediated facilitation of LTP

Autori: André Jerónimo-Santos, Vânia L. Batalha, Christa E. Müller, Younis Baqi, Ana Maria Sebastião, Luisa V. Lopes, Maria José Diógenes
Pubblicato in: Neuropharmacology, Numero 00283908, 2014, Pagina/e 99-106, ISSN 0028-3908
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Mechanisms of Regulation of Olfactory Transduction and Adaptation in the Olfactory Cilium

Autori: Gabriela Antunes, Ana Maria Sebastião, Fabio Marques Simoes de Souza
Pubblicato in: PLoS ONE, Numero 19326203, 2014, Pagina/e e105531, ISSN 1932-6203
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Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration

Autori: Julie van der Zee, Tim Van Langenhove, Gabor G. Kovacs, Lubina Dillen, William Deschamps, Sebastiaan Engelborghs, Radoslav Matěj, Mathieu Vandenbulcke, Anne Sieben, Bart Dermaut, Katrien Smets, Philip Van Damme, Céline Merlin, Annelies Laureys, Marleen Van Den Broeck, Maria Mattheijssens, Karin Peeters, Luisa Benussi, Giuliano Binetti, Roberta Ghidoni, Barbara Borroni, Alessandro Padovani, Silvana Archetti, Pau Pastor, Cristina Razquin, Sara Ortega-Cubero, Isabel Hernández, Mercè Boada, Agustín Ruiz, Alexandre de Mendonça, Gabriel Miltenberger-Miltényi, Frederico Simões do Couto, Sandro Sorbi, Benedetta Nacmias, Silvia Bagnoli, Caroline Graff, Huei-Hsin Chiang, Håkan Thonberg, Robert Perneczky, Janine Diehl-Schmid, Panagiotis Alexopoulos, Giovanni B. Frisoni, Christian Bonvicini, Matthis Synofzik, Walter Maetzler, Jennifer Müller vom Hagen, Ludger Schöls, Tobias B. Haack, Tim M. Strom, Holger Prokisch, Oriol Dols-Icardo, Jordi Clarimón, Alberto Lleó, Isabel Santana, Maria Rosário Almeida, Beatriz Santiago, Michael T. Heneka, Frank Jessen, Alfredo Ramirez, Raquel Sanchez-Valle, Albert Llado, Ellen Gelpi, Stayko Sarafov, Ivailo Tournev, Albena Jordanova, Eva Parobkova, Gian Maria Fabrizi, Silvia Testi, Eric Salmon, Thomas Ströbel, Patrick Santens, Wim Robberecht, Peter De Jonghe, Jean-Jacques Martin, Patrick Cras, Rik Vandenberghe, Peter Paul De Deyn, Marc Cruts, Kristel Sleegers, Christine Van Broeckhoven
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Overexpression of Adenosine A2A Receptors in Rats: Effects on Depression, Locomotion, and Anxiety

Autori: Joana E. Coelho, Pedro Alves, Paula M. Canas, Jorge S. Valadas, Tatiana Shmidt, VÃ¢nia L. Batalha, Diana G. Ferreira, Joaquim A. Ribeiro, Michael Bader, Rodrigo A. Cunha, Frederico SimÃµes do Couto, LuÃsa V. Lopes
Pubblicato in: Frontiers in Psychiatry, Numero 16640640, 2014, ISSN 1664-0640
Editore: Frontiers Research Foundation
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P2Y 1 receptor inhibits GABA transport through a calcium signalling-dependent mechanism in rat cortical astrocytes

Autori: Pedro F. Jacob, Sandra H. Vaz, Joaquim A. Ribeiro, Ana M. Sebastião
Pubblicato in: Glia, Numero 08941491, 2014, Pagina/e 1211-1226, ISSN 0894-1491
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Delayed diagnosis in ALS: The problem continues

Autori: Hipolito Nzwalo, Daisy de Abreu, Michael Swash, Susana Pinto, Mamede de Carvalho
Pubblicato in: Journal of the Neurological Sciences, Numero 0022510X, 2014, Pagina/e 173-175, ISSN 0022-510X
Editore: Elsevier BV
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Multicentre quality control evaluation of different biomarker candidates for amyotrophic lateral sclerosis

Autori: Stefan Lehnert, Julia Costa, Mamede de Carvalho, Janine Kirby, Magdalena Kuzma-Kozakiewicz, Claudia Morelli, Wim Robberecht, Pamela Shaw, Vincenzo Silani, Petra Steinacker, Hayrettin Tumani, Philip Van Damme, Albert Ludolph, Markus Otto
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Modeling the functional network of primary intercellular Ca2+ wave propagation in astrocytes and its application to study drug effects

Autori: Marcelo Pires, Frank Raischel, Sandra H. Vaz, Andreia Cruz-Silva, Ana M. Sebastião, Pedro G. Lind
Pubblicato in: Journal of Theoretical Biology, Numero 00225193, 2014, Pagina/e 201-212, ISSN 0022-5193
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Motoneuron firing in amyotrophic lateral sclerosis (ALS)

Autori: Mamede de Carvalho, Andrew Eisen, Charles Krieger, Michael Swash
Pubblicato in: Frontiers in Human Neuroscience, Numero 16625161, 2014, ISSN 1662-5161
Editore: Frontiers Research Foundation
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Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS)

Autori: Jean-Pascal Lefaucheur, Nathalie André-Obadia, Andrea Antal, Samar S. Ayache, Chris Baeken, David H. Benninger, Roberto M. Cantello, Massimo Cincotta, Mamede de Carvalho, Dirk De Ridder, Hervé Devanne, Vincenzo Di Lazzaro, Saša R. Filipović, Friedhelm C. Hummel, Satu K. Jääskeläinen, Vasilios K. Kimiskidis, Giacomo Koch, Berthold Langguth, Thomas Nyffeler, Antonio Oliviero, Frank Padberg, Emmanuel Poulet, Simone Rossi, Paolo Maria Rossini, John C. Rothwell, Carlos Schönfeldt-Lecuona, Hartwig R. Siebner, Christina W. Slotema, Charlotte J. Stagg, Josep Valls-Sole, Ulf Ziemann, Walter Paulus, Luis Garcia-Larrea
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Neurophysiological techniques to detect early small-fiber dysfunction in transthyretin amyloid polyneuropathy

Autori: Isabel Conceição, João Costa, José Castro, Mamede de Carvalho
Pubblicato in: Muscle & Nerve, Numero 0148639X, 2014, Pagina/e 181-186, ISSN 0148-639X
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Challenges and Promises in the Development of Neurotrophic Factor-Based Therapies for Parkinson’s Disease

Autori: Tiago Martins Rodrigues, André Jerónimo-Santos, Tiago Fleming Outeiro, Ana Maria Sebastião, Maria José Diógenes
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Sensitivity of MUP parameters in detecting change in early ALS

Autori: Mamede de Carvalho, Antonia Turkman, Michael Swash
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A handful of promises

Autori: Mamede de Carvalho
Pubblicato in: Clinical Neurophysiology, Numero 13882457, 2014, Pagina/e 5, ISSN 1388-2457
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Homeostatic Control of Synaptic Activity by Endogenous Adenosine is Mediated by Adenosine Kinase

Autori: M. J. Diogenes, R. Neves-Tome, S. Fucile, K. Martinello, M. Scianni, P. Theofilas, J. Lopatar, J. A. Ribeiro, L. Maggi, B. G. Frenguelli, C. Limatola, D. Boison, A. M. Sebastiao
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Breathing new life into treatment advances for respiratory failure in amyotrophic lateral sclerosis patients

Autori: Susana Pinto, Mamede de Carvalho
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From epidemiology to pathophysiology: what about caffeine in Alzheimer's disease?

Autori: Vanessa Flaten, Cyril Laurent, Joana E. Coelho, Ursula Sandau, Vânia L. Batalha, Sylvie Burnouf, Malika Hamdane, Sandrine Humez, Detlev Boison, Luísa V. Lopes, Luc Buée, David Blum
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Modulation of subventricular zone oligodendrogenesis: a role for hemopressin?

Autori: Sara Xapelli, Fabienne Agasse, Sofia Grade, Liliana Bernardino, Filipa F. Ribeiro, Clarissa S. Schitine, Andrea S. Heimann, Emer S. Ferro, Ana M. Sebasti, Ricardo A. De Melo Reis, João O. Malva
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Roles of Vascular Endothelial Growth Factor in Amyotrophic Lateral Sclerosis

Autori: Ana Catarina Pronto-Laborinho, Susana Pinto, Mamede de Carvalho
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A blinded international study on the reliability of genetic testing for GGGGCC-repeat expansions in C9orf72 reveals marked differences in results among 14 laboratories

Autori: C. Akimoto, A. E. Volk, M. van Blitterswijk, M. Van den Broeck, C. S. Leblond, S. Lumbroso, W. Camu, B. Neitzel, O. Onodera, W. van Rheenen, S. Pinto, M. Weber, B. Smith, M. Proven, K. Talbot, P. Keagle, A. Chesi, A. Ratti, J. van der Zee, H. Alstermark, A. Birve, D. Calini, A. Nordin, D. C. Tradowsky, W. Just, H. Daoud, S. Angerbauer, M. DeJesus-Hernandez, T. Konno, A. Lloyd-Jani, M. de Carvalho, K. Mouzat, J. E. Landers, J. H. Veldink, V. Silani, A. D. Gitler, C. E. Shaw, G. A. Rouleau, L. H. van den Berg, C. Van Broeckhoven, R. Rademakers, P. M. Andersen, C. Kubisch
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Editore: British Medical Association
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Genetic and biochemical markers in patients with Alzheimer's disease support a concerted systemic iron homeostasis dysregulation

Autori: Ângela C. Crespo, Bruno Silva, Liliana Marques, Erica Marcelino, Carolina Maruta, Sónia Costa, Ângela Timóteo, Arminda Vilares, Frederico Simões Couto, Paula Faustino, Ana Paula Correia, Ana Verdelho, Graça Porto, Manuela Guerreiro, Ana Herrero, Cristina Costa, Alexandre de Mendonça, Luciana Costa, Madalena Martins
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Editore: Elsevier BV
DOI: 10.1016/j.neurobiolaging.2013.10.078

Adenosine A2A Receptors as novel upstream regulators of BDNF-mediated attenuation of hippocampal Long-Term Depression (LTD)

Autori: Tiago M. Rodrigues, André Jerónimo-Santos, Ana M. Sebastião, Maria José Diógenes
Pubblicato in: Neuropharmacology, Numero 00283908, 2014, Pagina/e 389-398, ISSN 0028-3908
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2013.12.010

Vascular endothelial growth factor and amyotrophic lateral sclerosis: The interplay with exercise and noninvasive ventilation

Autori: Rita Carilho, Mamede de Carvalho, Michael Swash, Susana Pinto, Anabela Pinto, Júlia Costa
Pubblicato in: Muscle & Nerve, Numero 0148639X, 2014, Pagina/e 545-550, ISSN 0148-639X
Editore: John Wiley & Sons Inc.
DOI: 10.1002/mus.23955

GlyT1 and GlyT2 in brain astrocytes: expression, distribution and function

Autori: Rita I. Aroeira, Ana M. Sebastião, Cláudia A. Valente
Pubblicato in: Brain Structure and Function, Numero 18632653, 2014, Pagina/e 817-830, ISSN 1863-2653
Editore: Springer Verlag
DOI: 10.1007/s00429-013-0537-3

Nerve excitabitability and fasciculations

Autori: Mamede de Carvalho
Pubblicato in: Clinical Neurophysiology, Numero 13882457, 2013, Pagina/e 1925, ISSN 1388-2457
Editore: Elsevier BV
DOI: 10.1016/j.clinph.2013.03.022

Quality of life in patients with cognitive impairment: validation of the Quality of Life–Alzheimer's Disease scale in Portugal

Autori: Helena Bárrios, Ana Verdelho, Sofia Narciso, Manuel Gonçalves-Pereira, Rebecca Logsdon, Alexandre de Mendonça
Pubblicato in: International Psychogeriatrics, Numero 10416102, 2013, Pagina/e 1085-1096, ISSN 1041-6102
Editore: Cambridge University Press
DOI: 10.1017/S1041610213000379

A1R–A2AR heteromers coupled to Gs and Gi/0 proteins modulate GABA transport into astrocytes

Autori: Sofia Cristóvão-Ferreira, Gemma Navarro, Marc Brugarolas, Kamil Pérez-Capote, Sandra H. Vaz, Giorgia Fattorini, Fiorenzo Conti, Carmen Lluis, Joaquim A. Ribeiro, Peter J. McCormick, Vicent Casadó, Rafael Franco, Ana M. Sebastião
Pubblicato in: Purinergic Signalling, Numero 15739538, 2013, Pagina/e 433-449, ISSN 1573-9538
Editore: Springer Verlag
DOI: 10.1007/s11302-013-9364-5

Origin of Fasciculations in Amyotrophic Lateral Sclerosis and Benign Fasciculation Syndrome

Autori: Mamede de Carvalho, Michael Swash
Pubblicato in: JAMA Neurology, Numero 21686149, 2013, ISSN 2168-6149
Editore: American Medical Association
DOI: 10.1001/jamaneurol.2013.4437

Do MCI patients with vitamin B12 deficiency have distinctive cognitive deficits?

Autori: Dina Silva, Ulrike Albers, Isabel Santana, Margarida Vicente, Isabel Martins, Ana Verdelho, Manuela Guerreiro, Alexandre de-Mendonça
Pubblicato in: BMC Research Notes, Numero 17560500, 2013, Pagina/e 357, ISSN 1756-0500
Editore: BioMed Central
DOI: 10.1186/1756-0500-6-357

Reduced Myocardial 123-Iodine Metaiodobenzylguanidine Uptake: A Prognostic Marker in Familial Amyloid Polyneuropathy

Autori: M. C. A. Coutinho, N. Cortez-Dias, G. Cantinho, I. Conceicao, A. Oliveira, A. Bordalo e Sa, S. Goncalves, A. G. Almeida, M. de Carvalho, A. N. Diogo
Pubblicato in: Circulation: Cardiovascular Imaging, Numero 19419651, 2013, Pagina/e 627-636, ISSN 1941-9651
Editore: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCIMAGING.112.000367

Activation of Type 1 Cannabinoid Receptor (CB1R) Promotes Neurogenesis in Murine Subventricular Zone Cell Cultures

Autori: Sara Xapelli, Fabienne Agasse, Laura Sardà-Arroyo, Liliana Bernardino, Tiago Santos, Filipa F. Ribeiro, Jorge Valero, José Bragança, Clarissa Schitine, Ricardo A. de Melo Reis, Ana M. Sebastião, João O. Malva
Pubblicato in: PLoS ONE, Numero 19326203, 2013, Pagina/e e63529, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0063529

Hypoxia–Ischemia Alters Nucleotide and Nucleoside Catabolism and Na+,K+-ATPase Activity in the Cerebral Cortex of Newborn Rats

Autori: Victor Camera Pimentel, Daniela Zanini, Andréia Machado Cardoso, Roberta Schmatz, Margarete Dulce Bagatini, Jessié Martins Gutierres, Fabiano Carvalho, Jéssica Lopes Gomes, Maribel Rubin, Vera Maria Morsch, Maria Beatriz Moretto, Mariana Colino-Oliveira, Ana Maria Sebastião, Maria Rosa Chitolina Schetinger
Pubblicato in: Neurochemical Research, Numero 03643190, 2013, Pagina/e 886-894, ISSN 0364-3190
Editore: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s11064-013-0994-3

No association between VAPB mutations and familial or sporadic ALS in Sweden, Portugal and Iceland

Autori: Caroline Ingre, Susana Pinto, Anna Birve, Rayomand Press, Olof Danielsson, Mamede de Carvalho, Grétar Guđmundsson, Peter M. Andersen
Pubblicato in: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Numero 21678421, 2013, Pagina/e 620-627, ISSN 2167-8421
Editore: Informa Healthcare
DOI: 10.3109/21678421.2013.822515

Adenosine: setting the stage for plasticity

Autori: Raquel B. Dias, Diogo M. Rombo, Joaquim A. Ribeiro, Jeremy M. Henley, Ana M. Sebastião
Pubblicato in: Trends in Neurosciences, Numero 01662236, 2013, Pagina/e 248-257, ISSN 0166-2236
Editore: Elsevier BV
DOI: 10.1016/j.tins.2012.12.003

Early Changes of Neuromuscular Transmission in the SOD1(G93A) Mice Model of ALS Start Long before Motor Symptoms Onset

Autori: Mariana C. Rocha, Paula A. Pousinha, Alexandra M. Correia, Ana M. Sebastião, Joaquim A. Ribeiro
Pubblicato in: PLoS ONE, Numero 19326203, 2013, Pagina/e e73846, ISSN 1932-6203
Editore: Public Library of Science
DOI: 10.1371/journal.pone.0073846

Controversies and priorities in amyotrophic lateral sclerosis

Autori: Martin R Turner, Orla Hardiman, Michael Benatar, Benjamin R Brooks, Adriano Chio, Mamede de Carvalho, Paul G Ince, Cindy Lin, Robert G Miller, Hiroshi Mitsumoto, Garth Nicholson, John Ravits, Pamela J Shaw, Michael Swash, Kevin Talbot, Bryan J Traynor, Leonard H Van den Berg, Jan H Veldink, Steve Vucic, Matthew C Kiernan
Pubblicato in: The Lancet Neurology, Numero 14744422, 2013, Pagina/e 310-322, ISSN 1474-4422
Editore: The Lancet Publishing Group
DOI: 10.1016/S1474-4422(13)70036-X

Evidence that conditioned avoidance responses are reinforced by positive prediction errors signaled by tonic striatal dopamine

Autori: Patricia A. Dombrowski, Tiago V. Maia, Suelen L. Boschen, Mariza Bortolanza, Etieli Wendler, Rainer K.W. Schwarting, Marcus Lira Brandão, Philip Winn, Charles D. Blaha, Claudio Da Cunha
Pubblicato in: Behavioural Brain Research, Numero 01664328, 2013, Pagina/e 112-119, ISSN 0166-4328
Editore: Elsevier BV
DOI: 10.1016/j.bbr.2012.06.031

Tauroursodeoxycholic acid suppresses amyloid β-induced synaptic toxicity in vitro and in APP/PS1 mice

Autori: Rita M. Ramalho, Ana F. Nunes, Raquel B. Dias, Joana D. Amaral, Adrian C. Lo, Rudi D'Hooge, Ana M. Sebastião, Cecilia M.P. Rodrigues
Pubblicato in: Neurobiology of Aging, Numero 01974580, 2013, Pagina/e 551-561, ISSN 0197-4580
Editore: Elsevier BV
DOI: 10.1016/j.neurobiolaging.2012.04.018

Split-hand to diagnosis shot

Autori: Mamede de Carvalho
Pubblicato in: Clinical Neurophysiology, Numero 13882457, 2013, Pagina/e 219-220, ISSN 1388-2457
Editore: Elsevier BV
DOI: 10.1016/j.clinph.2012.08.015

A Pan-European Study of the C9orf72 Repeat Associated with FTLD: Geographic Prevalence, Genomic Instability, and Intermediate Repeats

Autori: Julie van der Zee, Ilse Gijselinck, Lubina Dillen, Tim Van Langenhove, Jessie Theuns, Sebastiaan Engelborghs, Stéphanie Philtjens, Mathieu Vandenbulcke, Kristel Sleegers, Anne Sieben, Veerle Bäumer, Githa Maes, Ellen Corsmit, Barbara Borroni, Alessandro Padovani, Silvana Archetti, Robert Perneczky, Janine Diehl-Schmid, Alexandre de Mendonça, Gabriel Miltenberger-Miltenyi, Sónia Pereira, José Pimentel, Benedetta Nacmias, Silvia Bagnoli, Sandro Sorbi, Caroline Graff, Huei-Hsin Chiang, Marie Westerlund, Raquel Sanchez-Valle, Albert Llado, Ellen Gelpi, Isabel Santana, Maria Rosário Almeida, Beatriz Santiago, Giovanni Frisoni, Orazio Zanetti, Cristian Bonvicini, Matthis Synofzik, Walter Maetzler, Jennifer Müller vom Hagen, Ludger Schöls, Michael T. Heneka, Frank Jessen, Radoslav Matej, Eva Parobkova, Gabor G. Kovacs, Thomas Ströbel, Stayko Sarafov, Ivailo Tournev, Albena Jordanova, Adrian Danek, Thomas Arzberger, Gian Maria Fabrizi, Silvia Testi, Eric Salmon, Patrick Santens, Jean-Jacques Martin, Patrick Cras, Rik Vandenberghe, Peter Paul De Deyn, Marc Cruts, Christine Van Broeckhoven, Julie van der Zee, Ilse Gijselinck, Lubina Dillen, Tim Van Langenhove, Jessie Theuns, Stéphanie Philtjens, Kristel Sleegers, Veerle Bäumer, Githa Maes, Ellen Corsmit, Marc Cruts, Christine Van Broeckhoven, Julie van der Zee, Ilse Gijselinck, Lubina Dillen, Tim Van Langenhove, Stéphanie Philtjens, Jessie Theuns, Kristel Sleegers, Veerle Bäumer, Githa Maes, Marc Cruts, Christine Van Broeckhoven, Sebastiaan Engelborghs, Peter P. De Deyn, Patrick Cras, Sebastiaan Engelborghs, Peter P. De Deyn, Mathieu Vandenbulcke, Mathieu Vandenbulcke, Barbara Borroni, Alessandro Padovani, Silvana Archetti, Robert Perneczky, Janine Diehl-Schmid, Matthis Synofzik, Walter Maetzler, Jennifer Müller vom Hagen, Ludger Schöls, Matthis Synofzik, Walter Maetzler, Jennifer Müller vom Hagen, Ludger Schöls, Michael T. Heneka, Frank Jessen, Alfredo Ramirez, Delia Kurzwelly, Carmen Sachtleben, Wolfgang Mairer, Alexandre de Mendonça, Gabriel Miltenberger-Miltenyi, Sónia Pereira, Clara Firmo, José Pimentel, Raquel Sanchez-Valle, Albert Llado, Anna Antonell, Jose Molinuevo, Ellen Gelpi, Caroline Graff, Huei-Hsin Chiang, Marie Westerlund, Caroline Graff, Anne Kinhult Ståhlbom, Håkan Thonberg, Inger Nennesmo, Anne Börjesson-Hanson, Benedetta Nacmias, Silvia Bagnoli, Sandro Sorbi, Valentina Bessi, Irene Piaceri, Isabel Santana, Beatriz Santiago, Isabel Santana, Maria Helena Ribeiro, Maria Rosário Almeida, Catarina Oliveira, João Massano, Carolina Garret, Paula Pires, Giovanni Frisoni, Orazio Zanetti, Cristian Bonvicini, Stayko Sarafov, Ivailo Tournev, Albena Jordanova, Ivailo Tournev, Gabor G. Kovacs, Thomas Ströbel, Michael T. Heneka, Frank Jessen, Alfredo Ramirez, Delia Kurzwelly, Carmen Sachtleben, Wolfgang Mairer, Frank Jessen, Radoslav Matej, Eva Parobkova, Adrian Danel, Thomas Arzberger, Gian Maria Fabrizi, Silvia Testi, Sergio Ferrari, Tiziana Cavallaro, Eric Salmon, Patrick Santens, Patrick Cras
Pubblicato in: Human Mutation, Numero 10597794, 2013, Pagina/e 363-373, ISSN 1059-7794
Editore: John Wiley & Sons Inc.
DOI: 10.1002/humu.22244

Ischemia-induced synaptic plasticity drives sustained expression of calcium-permeable AMPA receptors in the hippocampus

Autori: Raquel B. Dias, Diogo M. Rombo, Joaquim A. Ribeiro, Ana M. Sebastião
Pubblicato in: Neuropharmacology, Numero 00283908, 2013, Pagina/e 114-122, ISSN 0028-3908
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2012.09.016

Lipid rafts, synaptic transmission and plasticity: Impact in age-related neurodegenerative diseases

Autori: Ana M. Sebastião, Mariana Colino-Oliveira, Natália Assaife-Lopes, Raquel B. Dias, Joaquim A. Ribeiro
Pubblicato in: Neuropharmacology, Numero 00283908, 2013, Pagina/e 97-107, ISSN 0028-3908
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2012.06.053

Rapidly progressive frontotemporal dementia and bulbar amyotrophic lateral sclerosis in Portuguese patients with C9orf72 mutation

Autori: Catarina Chester, Mamede de Carvalho, Gabriel Miltenberger, Sónia Pereira, Lubina Dillen, Julie van der Zee, Christine van Broeckhoven, Alexandre de Mendonça
Pubblicato in: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Numero 21678421, 2013, Pagina/e 70-72, ISSN 2167-8421
Editore: Informa Healthcare
DOI: 10.3109/17482968.2012.690418

Orofacial Apraxia in Motor Neuron Disease

Autori: Patrícia Pita Lobo, Susana Pinto, Luz Rocha, Sofia Reimão, Mamede de Carvalho
Pubblicato in: Case Reports in Neurology, Numero 1662680X, 2013, Pagina/e 47-51, ISSN 1662-680X
Editore: S. Karger AG
DOI: 10.1159/000349895

Phenotypic variability of familial and sporadic Progranulin p.Gln257Profs*27 mutation

Autori: Pires C, Coelho M, Valadas A, Barroso C, Pimentel J, Martins M, Duyckaerts C, de Mendonça A, Verdelho A, Miltenberger-Miltenyi G
Pubblicato in: J Alzheimers Dis. 2013;37(2):335-42, Numero 18758908, 2013, ISSN 1875-8908
Editore: IOS Press
DOI: 10.3233/JAD-130146

Quality of life in patients with mild cognitive impairment

Autori: Helena Bárrios, Sofia Narciso, Manuela Guerreiro, João Maroco, Rebecca Logsdon, Alexandre de Mendonça
Pubblicato in: Aging & Mental Health, Numero 13607863, 2013, Pagina/e 287-292, ISSN 1360-7863
Editore: Carfax Publishers
DOI: 10.1080/13607863.2012.747083

Prediction of long-term (5 years) conversion to dementia using neuropsychological tests in a memory clinic setting

Autori: Silva D, Guerreiro M, Santana I, Rodrigues A, Cardoso S, Maroco J, de Mendonça A.
Pubblicato in: J Alzheimers Dis. 2013;34(3):681-9, Numero 18758908, 2013, ISSN 1875-8908
Editore: IOS Press
DOI: 10.3233/JAD-122098

Regulation of TrkB receptor translocation to lipid rafts by adenosine A2A receptors and its functional implications for BDNF-induced regulation of synaptic plasticity

Autori: Natália Assaife-Lopes, Vasco C. Sousa, Daniela B. Pereira, Joaquim A. Ribeiro, Ana M. Sebastião
Pubblicato in: Purinergic Signalling, Numero 15739538, 2014, Pagina/e 251-267, ISSN 1573-9538
Editore: Springer Verlag
DOI: 10.1007/s11302-013-9383-2

Role of Adenosine Receptors in Epileptic Seizures

Autori: Diogo Miguel Rombo, Joaquim Alexandre Ribeiro, Ana Maria Sebastião
Pubblicato in: The Adenosine Receptors, 2018, Pagina/e 309-350, ISBN 978-3-319-90807-6
Editore: Springer International Publishing
DOI: 10.1007/978-3-319-90808-3_13

Neurologic complications of craniovertebral dislocation

Autori: Mamede de Carvalho, Michael Swash
Pubblicato in: Neurologic Aspects of Systemic Disease Part I, 2014, Pagina/e 435-448, ISBN 9780702040863
Editore: Elsevier
DOI: 10.1016/B978-0-7020-4086-3.00028-X

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