Neurologic and Psychiatric Disorders: from synapses to networks

Resultado final

Public sessions debates on neuroscientific topics with societal impact quantified and assessed
1st Annual Scientific Meeting (kickoff meeting) announced and programmed
3rd Annual Scientific Meeting accomplished
4th Annual Scientific Meeting accomplished

4th (Final) Annual Scientific Meeting accomplished. This will be the final scientific meeting of SynaNet

Participation of students from the University of Lisbon at the Workshops, Lectures and seminars promoted by SynaNet members quantified (3rd year)
Participation of students from the University of Lisbon at the Workshops, Lectures and seminars promoted by SynaNet members quantified (1st year)
Joint projects and student co-supervision between SynaNet in particular in the areas of interface between different disciplines quantified
2nd Annual Scientific Meeting accomplished
Participation of students from the University of Lisbon at the Workshops, Lectures and seminars promoted by SynaNet members quantified (2nd)

Participation of students from the University of Lisbon at the Workshops, Lectures and seminars promoted by SynaNet members quantified (2nd year)

SynaNet webpage made visible

Publicaciones

Dual Influence of Endocannabinoids on Long-Term Potentiation of Synaptic Transmission

Autores: Armando Silva-Cruz, Mattias Carlström, Joaquim A. Ribeiro, Ana M. Sebastião
Publicado en: Frontiers in Pharmacology, Edición 8, 2017, ISSN 1663-9812
Editor: Frontiers Media S.A.
DOI: 10.3389/fphar.2017.00921

Interaction between Cannabinoid Type 1 and Type 2 Receptors in the Modulation of Subventricular Zone and Dentate Gyrus Neurogenesis

Autores: Rui S. Rodrigues, Filipa F. Ribeiro, Filipa Ferreira, Sandra H. Vaz, Ana M. Sebastião, Sara Xapelli
Publicado en: Frontiers in Pharmacology, Edición 8, 2017, ISSN 1663-9812
Editor: Frontiers Media S.A.
DOI: 10.3389/fphar.2017.00516

Scalable, Lightweight, Integrated and Quick-to-Assemble (SLIQ) Hyperdrives for Functional Circuit Dissection

Autores: Li Liang, Stefan N. Oline, Justin C. Kirk, Lukas Ian Schmitt, Robert W. Komorowski, Miguel Remondes, Michael M. Halassa
Publicado en: Frontiers in Neural Circuits, Edición 11, 2017, ISSN 1662-5110
Editor: Frontiers Research Foundation
DOI: 10.3389/fncir.2017.00008

Chronic and acute adenosine A2A receptor blockade prevents long-term episodic memory disruption caused by acute cannabinoid CB1 receptor activation

Autores: Francisco M. Mouro, Vânia L. Batalha, Diana G. Ferreira, Joana E. Coelho, Younis Baqi, Christa E. Müller, Luísa V. Lopes, Joaquim A. Ribeiro, Ana M. Sebastião
Publicado en: Neuropharmacology, Edición 117, 2017, Página(s) 316-327, ISSN 0028-3908
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2017.02.021

Downregulated Glia Interplay and Increased miRNA-155 as Promising Markers to Track ALS at an Early Stage

Autores: Carolina Cunha, Catarina Santos, Cátia Gomes, Adelaide Fernandes, Alexandra Marçal Correia, Ana Maria Sebastião, Ana Rita Vaz, Dora Brites
Publicado en: Molecular Neurobiology, 2018, ISSN 0893-7648
Editor: Humana Press, Inc.
DOI: 10.1007/s12035-017-0631-2

Inhibition of NMDA Receptors Prevents the Loss of BDNF Function Induced by Amyloid β

Autores: Sara R. Tanqueiro, Rita M. Ramalho, Tiago M. Rodrigues, Luísa V. Lopes, Ana M. Sebastião, Maria J. Diógenes
Publicado en: Frontiers in Pharmacology, Edición 9, 2018, ISSN 1663-9812
Editor: Frontiers Media S.A.
DOI: 10.3389/fphar.2018.00237

Enhanced LTP in aged rats: Detrimental or compensatory?

Autores: Júlia Pinho, Ruben Vale, Vânia L. Batalha, Ana Rita Costenla, Raquel Dias, Diogo Rombo, Ana M. Sebastião, Alexandre de Mendonça, Maria José Diógenes
Publicado en: Neuropharmacology, Edición 114, 2017, Página(s) 12-19, ISSN 0028-3908
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2016.11.017

Ex vivo model of epilepsy in organotypic slices—a new tool for drug screening

Autores: Daniela M. Magalhães, Noémia Pereira, Diogo M. Rombo, Cláudia Beltrão-Cavacas, Ana M. Sebastião, Cláudia A. Valente
Publicado en: Journal of Neuroinflammation, Edición 15/1, 2018, ISSN 1742-2094
Editor: BioMed Central
DOI: 10.1186/s12974-018-1225-2

Platinum Nanoparticle-Based Microreactors as Support for Neuroblastoma Cells

Autores: Ana Armada-Moreira, Essi Taipaleenmäki, Marie Baekgaard-Laursen, Philipp Sebastian Schattling, Ana M. Sebastião, Sandra H. Vaz, Brigitte Städler
Publicado en: ACS Applied Materials & Interfaces, Edición 10/9, 2018, Página(s) 7581-7592, ISSN 1944-8244
Editor: American Chemical Society
DOI: 10.1021/acsami.7b10724

Tauroursodeoxycholic Acid Enhances Mitochondrial Biogenesis, Neural Stem Cell Pool, and Early Neurogenesis in Adult Rats

Autores: Rita Soares, Filipa F. Ribeiro, Sara Xapelli, Tânia Genebra, Maria F. Ribeiro, Ana M. Sebastião, Cecília M. P. Rodrigues, Susana Solá
Publicado en: Molecular Neurobiology, 2018, ISSN 0893-7648
Editor: Humana Press, Inc.
DOI: 10.1007/s12035-017-0592-5

GAT-3 Dysfunction Generates Tonic Inhibition in External Globus Pallidus Neurons in Parkinsonian Rodents

Autores: Marine Chazalon, Elena Paredes-Rodriguez, Stéphanie Morin, Audrey Martinez, Sofia Cristóvão-Ferreira, Sandra Vaz, Ana Sebastiao, Aude Panatier, Eric Boué-Grabot, Cristina Miguelez, Jérôme Baufreton
Publicado en: Cell Reports, Edición 23/6, 2018, Página(s) 1678-1690, ISSN 2211-1247
Editor: Cell Press
DOI: 10.1016/j.celrep.2018.04.014

Glycine Receptor Activation Impairs ATP-Induced Calcium Transients in Cultured Cortical Astrocytes

Autores: Tatiana P. Morais, David Coelho, Sandra H. Vaz, Ana M. Sebastião, Cláudia A. Valente
Publicado en: Frontiers in Molecular Neuroscience, Edición 10, 2018, ISSN 1662-5099
Editor: Frontiers Research Foundation
DOI: 10.3389/fnmol.2017.00444

Constrained Nonlinear-Based Optimisation Applied to Fuzzy PID Controllers Tuning

Autores: Paulo Gil, Ana Sebastião, Catarina Lucena
Publicado en: Asian Journal of Control, Edición 20/1, 2018, Página(s) 135-148, ISSN 1561-8625
Editor: Chinese Automatic Control Society
DOI: 10.1002/asjc.1549

VPAC 1 and VPAC 2 receptor activation on GABA release from hippocampal nerve terminals involve several different signalling pathways

Autores: Diana Cunha-Reis, Joaquim Alexandre Ribeiro, Rodrigo F M de Almeida, Ana M Sebastião
Publicado en: British Journal of Pharmacology, Edición 174/24, 2017, Página(s) 4725-4737, ISSN 0007-1188
Editor: Wiley-Blackwell
DOI: 10.1111/bph.14051

On the role of stigmergy in cognition

Autores: Luís Correia, Ana M. Sebastião, Pedro Santana
Publicado en: Progress in Artificial Intelligence, Edición 6/1, 2017, Página(s) 79-86, ISSN 2192-6352
Editor: SPRINGER HEIDELBERG
DOI: 10.1007/s13748-016-0107-z

Dissecting neurovascular coupling mechanisms: a role for adenosine A 2A receptor

Autores: Nicholas Dale, Ana Maria Sebastião
Publicado en: Journal of Neurochemistry, Edición 140/1, 2017, Página(s) 10-12, ISSN 0022-3042
Editor: Blackwell Publishing Inc.
DOI: 10.1111/jnc.13896

Broad spectrum antiviral activity for paramyxoviruses is modulated by biophysical properties of fusion inhibitory peptides

Autores: Cyrille Mathieu, Marcelo T. Augusto, Stefan Niewiesk, Branka Horvat, Laura M. Palermo, Giuseppina Sanna, Silvia Madeddu, Devra Huey, Miguel A. R. B. Castanho, Matteo Porotto, Nuno C. Santos, Anne Moscona
Publicado en: Scientific Reports, Edición 7/1, 2017, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/srep43610

In Vivo Efficacy of Measles Virus Fusion Protein-Derived Peptides Is Modulated by the Properties of Self-Assembly and Membrane Residence

Autores: T. N. Figueira, L. M. Palermo, A. S. Veiga, D. Huey, C. A. Alabi, N. C. Santos, J. C. Welsch, C. Mathieu, B. Horvat, S. Niewiesk, A. Moscona, M. A. R. B. Castanho, M. Porotto
Publicado en: Journal of Virology, Edición 91/1, 2016, ISSN 0022-538X
Editor: American Society for Microbiology
DOI: 10.1128/jvi.01554-16

siRNA-cell-penetrating peptides complexes as a combinatorial therapy against chronic myeloid leukemia using BV173 cell line as model

Autores: Freire, JM (Freire, Joao Miguel)[ 1 ] ; de Figueiredo, IR (de Figueiredo, Ines Rego)[ 1 ] ; Valle, J (Valle, Javier)[ 2 ] ; Veiga, AS (Veiga, Ana Salome)[ 1 ] ; Andreu, D (Andreu, David)[ 2 ] ; Enguita, FJ (Enguita, Francisco J.)[ 1 ] ; Castanho, MARB (Castanho, Miguel A. R. B.)[ 1 ]
Publicado en: JOURNAL OF CONTROLLED RELEASE, 2017, ISSN 0168-3659
Editor: Elsevier BV
DOI: 10.1016/j.jconrel.2016.11.027

New Potent Membrane-Targeting Antibacterial Peptides from Viral Capsid Proteins

Autores: Susana A. Dias, João M. Freire, Clara Pérez-Peinado, Marco M. Domingues, Diana Gaspar, Nuno Vale, Paula Gomes, David Andreu, Sónia T. Henriques, Miguel A. R. B. Castanho, Ana S. Veiga
Publicado en: Frontiers in Microbiology, Edición 8, 2017, ISSN 1664-302X
Editor: Frontiers Media
DOI: 10.3389/fmicb.2017.00775

A New Noncanonical Anionic Peptide That Translocates a Cellular Blood–Brain Barrier Model

Autores: Sara Neves-Coelho, Rute Eleutério, Francisco Enguita, Vera Neves, Miguel Castanho
Publicado en: Molecules, Edición 22/10, 2017, Página(s) 1753, ISSN 1420-3049
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules22101753

Mechanisms of bacterial membrane permeabilization by crotalicidin (Ctn) and its fragment Ctn(15–34), antimicrobial peptides from rattlesnake venom

Autores: Clara Pérez-Peinado, Susana Almeida Dias, Marco M. Domingues, Aurélie H. Benfield, João Miguel Freire, Gandhi Rádis-Baptista, Diana Gaspar, Miguel A. R. B. Castanho, David J. Craik, Sónia Troeira Henriques, Ana Salomé Veiga, David Andreu
Publicado en: Journal of Biological Chemistry, Edición 293/5, 2018, Página(s) 1536-1549, ISSN 0021-9258
Editor: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/jbc.ra117.000125

Novel Peptides Derived from Dengue Virus Capsid Protein Translocate Reversibly the Blood–Brain Barrier through a Receptor-Free Mechanism

Autores: Vera Neves, Frederico Aires-da-Silva, Maurício Morais, Lurdes Gano, Elisabete Ribeiro, Antónia Pinto, Sandra Aguiar, Diana Gaspar, Célia Fernandes, João D. G. Correia, Miguel A. R. B. Castanho
Publicado en: ACS Chemical Biology, Edición 12/5, 2017, Página(s) 1257-1268, ISSN 1554-8929
Editor: American Chemical Society
DOI: 10.1021/acschembio.7b00087

Mechanisms of Vesicular Stomatitis Virus Inactivation by Protoporphyrin IX, Zinc-Protoporphyrin IX, and Mesoporphyrin IX

Autores: Christine Cruz-Oliveira, Andreza F. Almeida, João M. Freire, Marjolly B. Caruso, Maria A. Morando, Vivian N. S. Ferreira, Iranaia Assunção-Miranda, Andre M. O. Gomes, Miguel A. R. B. Castanho, Andrea T. Da Poian
Publicado en: Antimicrobial Agents and Chemotherapy, Edición 61/6, 2017, ISSN 0066-4804
Editor: American Society for Microbiology
DOI: 10.1128/aac.00053-17

Peptibodies: An elegant solution for a long-standing problem

Autores: Marco Cavaco, Miguel A. R. B. Castanho, Vera Neves
Publicado en: Peptide Science, Edición 110/1, 2018, Página(s) e23095, ISSN 2475-8817
Editor: WILEY
DOI: 10.1002/bip.23095

Neuropeptide Kyotorphin Impacts on Lipopolysaccharide-Induced Glucocorticoid-Mediated Inflammatory Response. A Molecular Link to Nociception, Neuroprotection, and Anti-Inflammatory Action

Autores: Juliana Perazzo, Carla Lima, Montserrat Heras, Eduard Bardají, Mônica Lopes-Ferreira, Miguel Castanho
Publicado en: ACS Chemical Neuroscience, Edición 8/8, 2017, Página(s) 1663-1667, ISSN 1948-7193
Editor: American Chemical Society
DOI: 10.1021/acschemneuro.7b00007

Pharmacological Potential of the Endogenous Dipeptide Kyotorphin and Selected Derivatives

Autores: Juliana Perazzo, Miguel A. R. B. Castanho, Sónia Sá Santos
Publicado en: Frontiers in Pharmacology, Edición 7, 2017, ISSN 1663-9812
Editor: Frontiers Media S.A.
DOI: 10.3389/fphar.2016.00530

Molecular determinants of the influenza fusion peptide activity

Autores: Diana Lousa, Antónia R.T. Pinto, Bruno L. Victor, Alessnadro Laio, Ana S. Veiga, Miguel A.R.B. Castanho, Cláudio M. Soares
Publicado en: Free Radical Biology and Medicine, Edición 120, 2018, Página(s) S125, ISSN 0891-5849
Editor: Elsevier BV
DOI: 10.1016/j.freeradbiomed.2018.04.413

Designing of Artificial Peptides for an Improved Antiviral Activity

Autores: Speranta Avram, Adina-Luminita Milac, Livia-Cristina Borcan, Dan Mihailescu, Florin Borcan, Miguel Castanho
Publicado en: Current Proteomics, Edición 15/4, 2018, Página(s) 258-266, ISSN 1570-1646
Editor: Bentham Science Publishers
DOI: 10.2174/1570164615666180409151111

Quantitative analysis of molecular partition towards lipid membranes using surface plasmon resonance

Autores: Tiago N. Figueira, João M. Freire, Catarina Cunha-Santos, Montserrat Heras, João Gonçalves, Anne Moscona, Matteo Porotto, Ana Salomé Veiga, Miguel A. R. B. Castanho
Publicado en: Scientific Reports, Edición 7/1, 2017, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/srep45647

Challenging metastatic breast cancer with the natural defensin Pv D 1

Autores: Tiago N. Figueira, Filipa D. Oliveira, Inês Almeida, Érica O. Mello, Valdirene M. Gomes, Miguel A. R. B. Castanho, Diana Gaspar
Publicado en: Nanoscale, Edición 9/43, 2017, Página(s) 16887-16899, ISSN 2040-3364
Editor: Royal Society of Chemistry
DOI: 10.1039/c7nr05872a

Motor unit number estimation (MUNE): Where are we now?

Autores: Mamede de Carvalho, Paul E. Barkhaus, Sanjeev D. Nandedkar, Michael Swash
Publicado en: Clinical Neurophysiology, Edición 129/8, 2018, Página(s) 1507-1516, ISSN 1388-2457
Editor: Elsevier BV
DOI: 10.1016/j.clinph.2018.04.748

Prolongation of terminal latency of the phrenic nerve in amyotrophic lateral sclerosis – Is it clinically useful, and what are the mechanisms?

Autores: Mamede de Carvalho
Publicado en: Clinical Neurophysiology, Edición 128/10, 2017, Página(s) 2094, ISSN 1388-2457
Editor: Elsevier BV
DOI: 10.1016/j.clinph.2017.07.404

Phrenic nerve stimulation is more sensitive than ultrasound measurement of diaphragm thickness in assessing early ALS progression

Autores: Susana Pinto, Pedro Alves, Michael Swash, Mamede de Carvalho
Publicado en: Neurophysiologie Clinique/Clinical Neurophysiology, Edición 47/1, 2017, Página(s) 69-73, ISSN 0987-7053
Editor: Elsevier Masson
DOI: 10.1016/j.neucli.2016.08.001

Diaphragm motor responses to phrenic nerve stimulation in ALS: Surface and needle recordings

Autores: Mamede de Carvalho, Susana Pinto, Michael Swash
Publicado en: Clinical Neurophysiology, Edición 129/2, 2018, Página(s) 349-353, ISSN 1388-2457
Editor: Elsevier BV
DOI: 10.1016/j.clinph.2017.11.019

Fasciculation in amyotrophic lateral sclerosis: origin and pathophysiological relevance

Autores: Mamede de Carvalho, Matthew C Kiernan, Michael Swash
Publicado en: Journal of Neurology, Neurosurgery & Psychiatry, Edición 88/9, 2017, Página(s) 773-779, ISSN 0022-3050
Editor: BMJ Publishing Group
DOI: 10.1136/jnnp-2017-315574

Fasciculation: Does distance really matter?

Autores: Mamede de Carvalho
Publicado en: Clinical Neurophysiology, Edición 129/2, 2018, Página(s) 462-463, ISSN 1388-2457
Editor: Elsevier BV
DOI: 10.1016/j.clinph.2017.11.021

Plasma level of club-cell (CC-16) predicts outcome in amyotrophic lateral sclerosis

Autores: A. C. Pronto-Laborinho, M. Gromicho, M. Pereira, S. Pinto, M. do A. Barros, M. Swash, M. de Carvalho
Publicado en: Acta Neurologica Scandinavica, Edición 137/2, 2018, Página(s) 233-237, ISSN 0001-6314
Editor: Blackwell Publishing Inc.
DOI: 10.1111/ane.12851

Cramps and vinpocetine in ALS

Autores: Mamede de Carvalho
Publicado en: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Edición 19/1-2, 2017, Página(s) 155-156, ISSN 2167-8421
Editor: Informa Healthcare
DOI: 10.1080/21678421.2017.1377735

Interplay of upper and lower motor neuron degeneration in amyotrophic lateral sclerosis

Autores: Mamede de Carvalho, Artiom Poliakov, Cristiano Tavares, Michael Swash
Publicado en: Clinical Neurophysiology, Edición 128/11, 2017, Página(s) 2200-2204, ISSN 1388-2457
Editor: Elsevier BV
DOI: 10.1016/j.clinph.2017.08.024

International Survey of ALS Experts about Critical Questions for Assessing Patients with ALS

Autores: Mamede De Carvalho, Adam Ryczkowski, Peter Andersen, Marta Gromicho, Julian Grosskreutz, Magdalena Kuźma-Kozakiewicz, Susanne Petri, Maria Piotrkiewicz, Gabriel Miltenberger Miltenyi
Publicado en: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Edición 18/7-8, 2017, Página(s) 505-510, ISSN 2167-8421
Editor: Informa Healthcare
DOI: 10.1080/21678421.2017.1349150

Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies

Autores: Hugo Vicente Miranda, Éva M. Szegő, Luís M. A. Oliveira, Carlo Breda, Ekrem Darendelioglu, Rita M. de Oliveira, Diana G. Ferreira, Marcos A. Gomes, Ruth Rott, Márcia Oliveira, Francesca Munari, Francisco J. Enguita, Tânia Simões, Eva F. Rodrigues, Michael Heinrich, Ivo C. Martins, Irina Zamolo, Olaf Riess, Carlos Cordeiro, Ana Ponces-Freire, Hilal A. Lashuel, Nuno C. Santos, Luisa V. Lopes,
Publicado en: Brain, Edición 140/5, 2017, Página(s) 1399-1419, ISSN 0006-8950
Editor: Oxford University Press
DOI: 10.1093/brain/awx056

α-synuclein interacts with PrPC to induce cognitive impairment through mGluR5 and NMDAR2B

Autores: Diana G Ferreira, Mariana Temido-Ferreira, Hugo Vicente Miranda, Vânia L Batalha, Joana E Coelho, Éva M Szegö, Inês Marques-Morgado, Sandra H Vaz, Jeong Seop Rhee, Matthias Schmitz, Inga Zerr, Luísa V Lopes, Tiago F Outeiro
Publicado en: Nature Neuroscience, Edición 20/11, 2017, Página(s) 1569-1579, ISSN 1097-6256
Editor: Nature Publishing Group
DOI: 10.1038/nn.4648

Adenosine A 2A Receptors Modulate α-Synuclein Aggregation and Toxicity

Autores: Diana G. Ferreira, Vânia L. Batalha, Hugo Vicente Miranda, Joana E. Coelho, Rui Gomes, Francisco Q. Gonçalves, Joana I. Real, José Rino, António Albino-Teixeira, Rodrigo A. Cunha, Tiago F. Outeiro, Luísa V. Lopes
Publicado en: Cerebral Cortex, 2017, Página(s) bhv268, ISSN 1047-3211
Editor: Oxford University Press
DOI: 10.1093/cercor/bhv268

Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca2+]i overload and NF-κB activation

Autores: Nadia A. Rivero-Segura, Edgar Flores-Soto, Selene García de la Cadena, Isabel Coronado-Mares, Juan C. Gomez-Verjan, Diana G. Ferreira, Erika Alejandra Cabrera-Reyes, Luísa V. Lopes, Lourdes Massieu, Marco Cerbón
Publicado en: PLOS ONE, Edición 12/5, 2017, Página(s) e0176910, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0176910

Mutant A53T α-Synuclein Improves Rotarod Performance Before Motor Deficits and Affects Metabolic Pathways

Autores: Patrícia S. Guerreiro, Joana E. Coelho, Inês Sousa-Lima, Paula Macedo, Luísa V. Lopes, Tiago F. Outeiro, Teresa F. Pais
Publicado en: NeuroMolecular Medicine, Edición 19/1, 2017, Página(s) 113-121, ISSN 1535-1084
Editor: Humana Press, Inc.
DOI: 10.1007/s12017-016-8435-5

Beneficial Effect of a Selective Adenosine A2A Receptor Antagonist in the APPswe/PS1dE9 Mouse Model of Alzheimer’s Disease

Autores: Emilie Faivre, Joana E. Coelho, Katja Zornbach, Enas Malik, Younis Baqi, Marion Schneider, Lucrezia Cellai, Kevin Carvalho, Shéhérazade Sebda, Martin Figeac, Sabiha Eddarkaoui, Raphaëlle Caillierez, Yijuang Chern, Michael Heneka, Nicolas Sergeant, Christa E. Müller, Annett Halle, Luc Buée, Luisa V. Lopes, David Blum
Publicado en: Frontiers in Molecular Neuroscience, Edición 11, 2018, ISSN 1662-5099
Editor: Frontiers Research Foundation
DOI: 10.3389/fnmol.2018.00235

Thrombolysis and thrombectomy in patients treated with dabigatran with acute ischemic stroke: Expert opinion

Autores: HC Diener, R Bernstein, K Butcher, B Campbell, G Cloud, A Davalos, S Davis, JM Ferro, M Grond, D Krieger, G Ntaios, A Slowik, E Touzé
Publicado en: International Journal of Stroke, Edición 12/1, 2016, Página(s) 9-12, ISSN 1747-4930
Editor: Blackwell
DOI: 10.1177/1747493016669849

European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis - endorsed by the European Academy of Neurology

Autores: J. M. Ferro, M.-G. Bousser, P. Canhão, J. M. Coutinho, I. Crassard, F. Dentali, M. di Minno, A. Maino, I. Martinelli, F. Masuhr, D. Aguiar de Sousa, J. Stam
Publicado en: European Journal of Neurology, Edición 24/10, 2017, Página(s) 1203-1213, ISSN 1351-5101
Editor: Blackwell Publishing Inc.
DOI: 10.1111/ene.13381

Cerebral venous thrombosis

Autores: Suzanne M. Silvis, Diana Aguiar de Sousa, José M. Ferro, Jonathan M Coutinho
Publicado en: Nature Reviews Neurology, Edición 13/9, 2017, Página(s) 555-565, ISSN 1759-4758
Editor: Nature Publishing Group
DOI: 10.1038/nrneurol.2017.104

Safety of Pregnancy After Cerebral Venous Thrombosis

Autores: Diana Aguiar de Sousa, Patrícia Canhão, Isabelle Crassard, Jonathan Coutinho, Antonio Arauz, Adriana Conforto, Yannick Béjot, Maurice Giroud, José M. Ferro, Teresa Pinho e Melo, Liliana Pereira, Elisa Costa, Miguel Rodrigues, Miguel Viana Baptista, Marta Carvalho, Gabriela Lopes, Manuel Correia, Ana Amélia Pinto, Paulo Coelho, Luís Cunha, Andreia Veiga, Mário Silva, Maria Manuela Costa, Hip
Publicado en: Stroke, Edición 48/11, 2017, Página(s) 3130-3133, ISSN 0039-2499
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.117.018829

Post-stroke seizures are clinically underestimated

Autores: Carla Bentes, Hugo Martins, Ana Rita Peralta, Carlos Casimiro, Carlos Morgado, Ana Catarina Franco, Ana Catarina Fonseca, Ruth Geraldes, Patrícia Canhão, Teresa Pinho e Melo, Teresa Paiva, José M. Ferro
Publicado en: Journal of Neurology, Edición 264/9, 2017, Página(s) 1978-1985, ISSN 0340-5354
Editor: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00415-017-8586-9

Five-Year Risk of Stroke after TIA or Minor Ischemic Stroke

Autores: Pierre Amarenco, Philippa C. Lavallée, Linsay Monteiro Tavares, Julien Labreuche, Gregory W. Albers, Halim Abboud, Sabrina Anticoli, Heinrich Audebert, Natan M. Bornstein, Louis R. Caplan, Manuel Correia, Geoffrey A. Donnan, José M. Ferro, Fernando Gongora-Rivera, Wolfgang Heide, Michael G. Hennerici, Peter J. Kelly, Michal Král, Hsiu-Fen Lin, Carlos Molina, Jong Moo Park, Francisco Purroy, Pet
Publicado en: New England Journal of Medicine, Edición 378/23, 2018, Página(s) 2182-2190, ISSN 0028-4793
Editor: Massachusetts Medical Society
DOI: 10.1056/nejmoa1802712

European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis – Endorsed by the European Academy of Neurology

Autores: José M Ferro, Marie-Germaine Bousser, Patrícia Canhão, Jonathan M Coutinho, Isabelle Crassard, Francesco Dentali, Matteo di Minno, Alberto Maino, Ida Martinelli, Florian Masuhr, Diana Aguiar de Sousa, Jan Stam
Publicado en: European Stroke Journal, Edición 2/3, 2017, Página(s) 195-221, ISSN 2396-9873
Editor: SAGE PUBLICATIONS LTD
DOI: 10.1177/2396987317719364

Epileptic manifestations in stroke patients treated with intravenous alteplase

Autores: C. Bentes, H. Martins, A. R. Peralta, C. Morgado, C. Casimiro, A. C. Franco, A. C. Fonseca, R. Geraldes, P. Canhão, T. Pinho e Melo, T. Paiva, J. M. Ferro
Publicado en: European Journal of Neurology, Edición 24/6, 2017, Página(s) 755-761, ISSN 1351-5101
Editor: Blackwell Publishing Inc.
DOI: 10.1111/ene.13292

Differences in Characteristics and Outcomes Between Asian and Non-Asian Patients in the TIAregistry.org

Autores: Takao Hoshino, Shinichiro Uchiyama, Lawrence K.S. Wong, Leila Sissani, Gregory W. Albers, Natan M. Bornstein, Louis R. Caplan, Geoffrey A. Donnan, José M. Ferro, Michael G. Hennerici, Julien Labreuche, Philippa C. Lavallée, Carlos Molina, Peter M. Rothwell, Philippe Gabriel Steg, Pierre-Jean Touboul, Éric Vicaut, Pierre Amarenco
Publicado en: Stroke, Edición 48/7, 2017, Página(s) 1779-1787, ISSN 0039-2499
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.117.016874

Symptomatic Patients Remain at Substantial Risk of Arterial Disease Complications Before and After Endarterectomy or Stenting

Autores: Cristina Hobeanu, Philippa C. Lavallée, Peter M. Rothwell, Leila Sissani, Gregory W. Albers, Natan M. Bornstein, Louis R. Caplan, Geoffrey A. Donnan, José M. Ferro, Michael G. Hennerici, Julien Labreuche, Carlos Molina, Philippe Gabriel Steg, Pierre-Jean Touboul, Shinichiro Uchiyama, Éric Vicaut, Lawrence K.S. Wong, Pierre Amarenco
Publicado en: Stroke, Edición 48/4, 2017, Página(s) 1005-1010, ISSN 0039-2499
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.116.015171

Patients With Undetermined Stroke Have Increased Atrial Fibrosis

Autores: Ana Catarina Fonseca, Pedro Alves, Nuno Inácio, João Pedro Marto, Miguel Viana-Baptista, Teresa Pinho-e-Melo, José M. Ferro, Ana G. Almeida
Publicado en: Stroke, Edición 49/3, 2018, Página(s) 734-737, ISSN 0039-2499
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.117.019641

Increase in the Admission of Stroke Mimics after Change in Emergency Shifts

Autores: Mariana Vargas, Mariana Costa, Teresa Pinho e Melo, José M. Ferro, Ana Catarina Fonseca
Publicado en: Cerebrovascular Diseases, Edición 44/1-2, 2017, Página(s) 68-74, ISSN 1015-9770
Editor: S. Karger AG
DOI: 10.1159/000475823

Patent foramen ovale and stroke

Autores: Bruno Miranda, Ana Catarina Fonseca, José M. Ferro
Publicado en: Journal of Neurology, Edición 265/8, 2018, Página(s) 1943-1949, ISSN 0340-5354
Editor: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00415-018-8865-0

Quantitative EEG and functional outcome following acute ischemic stroke

Autores: Carla Bentes, Ana Rita Peralta, Pedro Viana, Hugo Martins, Carlos Morgado, Carlos Casimiro, Ana Catarina Franco, Ana Catarina Fonseca, Ruth Geraldes, Patrícia Canhão, Teresa Pinho e Melo, Teresa Paiva, José M. Ferro
Publicado en: Clinical Neurophysiology, Edición 129/8, 2018, Página(s) 1680-1687, ISSN 1388-2457
Editor: Elsevier BV
DOI: 10.1016/j.clinph.2018.05.021

Frequency of post-stroke electroencephalographic epileptiform activity – a systematic review and meta-analysis of observational studies

Autores: Carla Bentes, Filipe B Rodrigues, Diana Sousa, Gonçalo S Duarte, Ana C Franco, Raquel Marques, Hipólito Nzwalo, Ana R Peralta, José M Ferro, João Costa
Publicado en: European Stroke Journal, Edición 2/4, 2017, Página(s) 361-368, ISSN 2396-9873
Editor: SAGE PUBLICATIONS LTD
DOI: 10.1177/2396987317731004

Safety of pregnancy after cerebral venous thrombosis: systematic review update

Autores: Diana Aguiar de Sousa, Patrícia Canhão, José M. Ferro
Publicado en: Journal of Neurology, Edición 265/1, 2018, Página(s) 211-212, ISSN 0340-5354
Editor: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00415-017-8666-x

Recanalization in Cerebral Venous Thrombosis

Autores: Diana Aguiar de Sousa, Lia Lucas Neto, Patrícia Canhão, José M. Ferro
Publicado en: Stroke, Edición 49/8, 2018, Página(s) 1828-1835, ISSN 0039-2499
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.118.022129

The impact of anger in adherence to treatment and beliefs about disease 1 year after stroke

Autores: A. Catarina Santos, José M. Ferro
Publicado en: Journal of Neurology, Edición 264/9, 2017, Página(s) 1929-1938, ISSN 0340-5354
Editor: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00415-017-8577-x

Can We Predict Who Will Develop Hypertension After Carotid Endarterectomy?

Autores: José M. Ferro
Publicado en: European Journal of Vascular and Endovascular Surgery, Edición 54/5, 2017, Página(s) 549-550, ISSN 1078-5884
Editor: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.ejvs.2017.09.001

Patients with undetermined ischemic stroke etiology show a high percentage of atrial tissue fibrosis

Autores: A.C. Fonseca, P. Nascimento, T. Pinho e Melo, P. Canhão, J.M. Ferro, A.G. Almeida
Publicado en: Journal of the Neurological Sciences, Edición 381, 2017, Página(s) 504, ISSN 0022-510X
Editor: Elsevier BV
DOI: 10.1016/j.jns.2017.08.3628

Epilepsia partialis continua after an anterior circulation ischaemic stroke

Autores: C. Bentes, A. C. Franco, A. R. Peralta, P. Viana, H. Martins, C. Morgado, C. Casimiro, C. Fonseca, R. Geraldes, P. Canhão, T. Pinho e Melo, T. Paiva, J. M. Ferro
Publicado en: European Journal of Neurology, Edición 24/7, 2017, Página(s) 929-934, ISSN 1351-5101
Editor: Blackwell Publishing Inc.
DOI: 10.1111/ene.13310

Validation of a Lower Back “Wearable”-Based Sit-to-Stand and Stand-to-Sit Algorithm for Patients With Parkinson's Disease and Older Adults in a Home-Like Environment

Autores: Minh H. Pham, Elke Warmerdam, Morad Elshehabi, Christian Schlenstedt, Lu-Marie Bergeest, Maren Heller, Linda Haertner, Joaquim J. Ferreira, Daniela Berg, Gerhard Schmidt, Clint Hansen, Walter Maetzler
Publicado en: Frontiers in Neurology, Edición 9, 2018, ISSN 1664-2295
Editor: Frontiers Research Foundation
DOI: 10.3389/fneur.2018.00652

Opicapone for the management of end-of-dose motor fluctuations in patients with Parkinson’s disease treated with L-DOPA

Autores: Andrew J. Lees, Joaquim Ferreira, Olivier Rascol, Heinz Reichmann, Fabrizio Stocchi, Eduardo Tolosa, Werner Poewe
Publicado en: Expert Review of Neurotherapeutics, Edición 17/7, 2017, Página(s) 649-659, ISSN 1473-7175
Editor: Future Drugs Ltd.
DOI: 10.1080/14737175.2017.1336086

Physician perception versus true efficacy of tetrabenazine for Huntington’s disease

Autores: Filipe B. Rodrigues, Joaquim J. Ferreira, Edward J. Wild
Publicado en: Current Medical Research and Opinion, Edición 34/9, 2018, Página(s) 1537-1538, ISSN 0300-7995
Editor: Librapharm Ltd.
DOI: 10.1080/03007995.2018.1490703

Quality and reporting of guidelines on the diagnosis and management of dystonia

Autores: G. Tamás, C. Abrantes, A. Valadas, P. Radics, A. Albanese, M. A. J. Tijssen, J. J. Ferreira
Publicado en: European Journal of Neurology, Edición 25/2, 2018, Página(s) 275-283, ISSN 1351-5101
Editor: Blackwell Publishing Inc.
DOI: 10.1111/ene.13488

Erratum - Information Sources and Decision-Making in Neurosurgery: Results of a Survey of Members of the Brazilian Neurosurgery Society

Autores: Rodrigo Gorayeb, Maria Forjaz, Antônio Gonçalves-Ferreira, Joaquim Ferreira
Publicado en: Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery, Edición 37/02, 2018, Página(s) 162-162, ISSN 0103-5355
Editor: GEORG THIEME VERLAG KG
DOI: 10.1055/s-0038-1667058

Information Sources and Decision-Making in Neurosurgery: Results of a Survey of Members of the Brazilian Neurosurgery Society

Autores: Rodrigo Gorayeb, Maria João Forjaz, Antônio Gonçalves-Ferreira, Joaquim Ferreira
Publicado en: Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery, Edición 37/02, 2018, Página(s) 081-087, ISSN 0103-5355
Editor: GEORG THIEME VERLAG KG
DOI: 10.1055/s-0038-1656716

Psychosocial impact of Parkinson's disease-associated dysarthria: Cross-cultural adaptation and validation of the Dysarthria Impact Profile into European Portuguese

Autores: Rita Cardoso, Isabel Guimarães, Helena Santos, Rita Loureiro, Josefa Domingos, Daisy Abreu, Nilza Gonçalves, Serge Pinto, Joaquim J Ferreira
Publicado en: Geriatrics & Gerontology International, Edición 18/5, 2018, Página(s) 767-774, ISSN 1444-1586
Editor: GEORG THIEME VERLAG KG
DOI: 10.1111/ggi.13255

Comments on: ‘Pyridostigmine bromide versus fludrocortisone in the treatment of orthostatic hypotension in Parkinson's disease - a randomized controlled trial’

Autores: R. M. Simões, A. Castro Caldas, J. J. Ferreira
Publicado en: European Journal of Neurology, Edición 25/1, 2018, Página(s) e4-e4, ISSN 1351-5101
Editor: Blackwell Publishing Inc.
DOI: 10.1111/ene.13475

Suspected adverse drug reaction reports with oral anticoagulants in Portugal: a pharmacovigilance study

Autores: Daniel Caldeira, Raquel Rodrigues, Daisy Abreu, Ana Marta Anes, Mário M. Rosa, Joaquim J. Ferreira
Publicado en: Expert Opinion on Drug Safety, Edición 17/4, 2018, Página(s) 339-345, ISSN 1474-0338
Editor: Ashley Publications Ltd.
DOI: 10.1080/14740338.2018.1439474

The launch of opicapone for Parkinson’s disease: negatives versus positives

Autores: Ana Castro Caldas, Tiago Teodoro, Joaquim J Ferreira
Publicado en: Expert Opinion on Drug Safety, Edición 17/3, 2018, Página(s) 331-337, ISSN 1474-0338
Editor: Ashley Publications Ltd.
DOI: 10.1080/14740338.2018.1433659

Mitochondrial quality control pathways: PINK1 acts as a gatekeeper

Autores: Elvira P. Leites, Vanessa A. Morais
Publicado en: Biochemical and Biophysical Research Communications, Edición 500/1, 2018, Página(s) 45-50, ISSN 0006-291X
Editor: Academic Press
DOI: 10.1016/j.bbrc.2017.06.096

β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog–Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models

Autores: Thomas Goiran, Eric Duplan, Mounia Chami, Alexandre Bourgeois, Wejdane El Manaa, Lila Rouland, Julie Dunys, Inger Lauritzen, Han You, Vuk Stambolic, Maria-Grazia Biféri, Martine Barkats, Sanjay W. Pimplikar, Nicolas Sergeant, Morvane Colin, Vanessa A. Morais, Raphaelle Pardossi-Piquard, Frédéric Checler, Cristine Alves da Costa
Publicado en: Biological Psychiatry, Edición 83/5, 2018, Página(s) 416-427, ISSN 0006-3223
Editor: Elsevier BV
DOI: 10.1016/j.biopsych.2017.04.011

Cardiolipin promotes electron transport between ubiquinone and complex I to rescue PINK1 deficiency

Autores: Melissa Vos, Ann Geens, Claudia Böhm, Liesbeth Deaulmerie, Jef Swerts, Matteo Rossi, Katleen Craessaerts, Elvira P. Leites, Philip Seibler, Aleksandar Rakovic, Thora Lohnau, Bart De Strooper, Sarah-Maria Fendt, Vanessa A. Morais, Christine Klein, Patrik Verstreken
Publicado en: The Journal of Cell Biology, Edición 216/3, 2017, Página(s) 695-708, ISSN 0021-9525
Editor: Rockefeller University Press
DOI: 10.1083/jcb.201511044

Chronic, intermittent treatment with a cannabinoid receptor agonist impairs recognition memory and brain network functional connectivity

Autores: Francisco M. Mouro, Joaquim A. Ribeiro, Ana M. Sebastião, Neil Dawson
Publicado en: Journal of Neurochemistry, Edición 147/1, 2018, Página(s) 71-83, ISSN 0022-3042
Editor: Blackwell Publishing Inc.
DOI: 10.1111/jnc.14549

Amyotrophic Lateral Sclerosis (ALS) and Adenosine Receptors

Autores: Ana M. Sebastião, Nádia Rei, Joaquim A. Ribeiro
Publicado en: Frontiers in Pharmacology, Edición 9, 2018, ISSN 1663-9812
Editor: Frontiers Media S.A.
DOI: 10.3389/fphar.2018.00267

Autophagy induction impairs Wnt/β-catenin signalling through β-catenin relocalisation in glioblastoma cells

Autores: Barbara Colella, Fiorella Faienza, Marianna Carinci, Giuseppina D'Alessandro, Myriam Catalano, Antonio Santoro, Francesco Cecconi, Cristina Limatola, Sabrina Di Bartolomeo
Publicado en: Cellular Signalling, Edición 53, 2019, Página(s) 357-364, ISSN 0898-6568
Editor: Elsevier BV
DOI: 10.1016/j.cellsig.2018.10.017

Kv1.3 activity perturbs the homeostatic properties of astrocytes in glioma

Autores: Alfonso Grimaldi, Giuseppina D’Alessandro, Maria Amalia Di Castro, Clotilde Lauro, Vikrant Singh, Francesca Pagani, Luigi Sforna, Francesca Grassi, Silvia Di Angelantonio, Luigi Catacuzzeno, Heike Wulff, Cristina Limatola, Myriam Catalano
Publicado en: Scientific Reports, Edición 8/1, 2018, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-018-25940-5

Decreased plasma C-reactive protein levels in APOE ε 4 allele carriers

Autores: Henna Martiskainen, Mari Takalo, Alina Solomon, Alena Stančáková, Mikael Marttinen, Teemu Natunen, Annakaisa Haapasalo, Sanna-Kaisa Herukka, Johanna Kuusisto, Hilkka Soininen, Miia Kivipelto, Markku Laakso, Mikko Hiltunen
Publicado en: Annals of Clinical and Translational Neurology, Edición 5/10, 2018, Página(s) 1229-1240, ISSN 2328-9503
Editor: WILEY
DOI: 10.1002/acn3.639

CXCL16/CXCR6 Axis Drives Microglia/Macrophages Phenotype in Physiological Conditions and Plays a Crucial Role in Glioma

Autores: Francesca Lepore, Giuseppina D'Alessandro, Fabrizio Antonangeli, Antonio Santoro, Vincenzo Esposito, Cristina Limatola, Flavia Trettel
Publicado en: Frontiers in Immunology, Edición 9, 2018, ISSN 1664-3224
Editor: FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2018.02750

Inflammation, neurodegeneration and protein aggregation in the retina as ocular biomarkers for Alzheimer’s disease in the 3xTg-AD mouse model

Autores: Alfonso Grimaldi, Carlo Brighi, Giovanna Peruzzi, Davide Ragozzino, Valentina Bonanni, Cristina Limatola, Giancarlo Ruocco, Silvia Di Angelantonio
Publicado en: Cell Death & Disease, Edición 9/6, 2018, ISSN 2041-4889
Editor: Nature Publishing Group
DOI: 10.1038/s41419-018-0740-5

Ca2+-activated K+ channels modulate microglia affecting motor neuron survival in hSOD1G93A mice

Autores: Germana Cocozza, Maria Amalia di Castro, Laura Carbonari, Alfonso Grimaldi, Fabrizio Antonangeli, Stefano Garofalo, Alessandra Porzia, Michele Madonna, Fabrizio Mainiero, Angela Santoni, Francesca Grassi, Heike Wulff, Giuseppina D'Alessandro, Cristina Limatola
Publicado en: Brain, Behavior, and Immunity, Edición 73, 2018, Página(s) 584-595, ISSN 0889-1591
Editor: Academic Press
DOI: 10.1016/j.bbi.2018.07.002

TrkB-ICD Fragment, Originating From BDNF Receptor Cleavage, Is Translocated to Cell Nucleus and Phosphorylates Nuclear and Axonal Proteins

Autores: João Fonseca-Gomes, André Jerónimo-Santos, Angelina Lesnikova, Plinio Casarotto, Eero Castrén, Ana M. Sebastião, Maria J. Diógenes
Publicado en: Frontiers in Molecular Neuroscience, Edición 12, 2019, ISSN 1662-5099
Editor: Frontiers Research Foundation
DOI: 10.3389/fnmol.2019.00004

Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice

Autores: Sami Gabbouj, Teemu Natunen, Hennariikka Koivisto, Kimmo Jokivarsi, Mari Takalo, Mikael Marttinen, Rebekka Wittrahm, Susanna Kemppainen, Reyhaneh Naderi, Adrián Posado-Fernández, Simo Ryhänen, Petra Mäkinen, Kaisa M.A. Paldanius, Gonçalo Doria, Pekka Poutiainen, Orfeu Flores, Annakaisa Haapasalo, Heikki Tanila, Mikko Hiltunen
Publicado en: Neurobiology of Aging, Edición 75, 2019, Página(s) 98-108, ISSN 0197-4580
Editor: Elsevier BV
DOI: 10.1016/j.neurobiolaging.2018.11.008

A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology

Autores: Mikael Marttinen, Jussi Paananen, Antonio Neme, Vikram Mitra, Mari Takalo, Teemu Natunen, Kaisa M.A. Paldanius, Petra Mäkinen, Michael Bremang, Mitja I. Kurki, Tuomas Rauramaa, Ville Leinonen, Hilkka Soininen, Annakaisa Haapasalo, Ian Pike, Mikko Hiltunen
Publicado en: Neurobiology of Disease, Edición 124, 2019, Página(s) 454-468, ISSN 0969-9961
Editor: Academic Press
DOI: 10.1016/j.nbd.2018.12.009

Adenosine A 2A receptors facilitate synaptic NMDA currents in CA1 pyramidal neurons

Autores: Francisco M Mouro, Diogo M Rombo, Raquel B Dias, Joaquim A Ribeiro, Ana M Sebastião
Publicado en: British Journal of Pharmacology, Edición 175/23, 2018, Página(s) 4386-4397, ISSN 0007-1188
Editor: Wiley-Blackwell
DOI: 10.1111/bph.14497

Brain-Derived Neurotrophic Factor (BDNF) Role in Cannabinoid-Mediated Neurogenesis

Autores: Filipa Fiel Ferreira, Filipa F. Ribeiro, Rui S. Rodrigues, Ana Maria Sebastião, Sara Xapelli
Publicado en: Frontiers in Cellular Neuroscience, Edición 12, 2018, ISSN 1662-5102
Editor: Frontiers Research Foundation
DOI: 10.3389/fncel.2018.00441

Anxiety Assessment in Pre-clinical Tests and in Clinical Trials: A Critical Review

Autores: Lígia Castanheira, Miguel F. Ferreira, Ana M. Sebastião, Diogo Telles-Correia
Publicado en: Current Topics in Medicinal Chemistry, Edición 18/19, 2018, Página(s) 1656-1676, ISSN 1568-0266
Editor: Bentham Science Publishers
DOI: 10.2174/1568026618666181115102518

Depression Assessment in Clinical Trials and Pre-clinical Tests: A Critical Review

Autores: Miguel F. Ferreira, Lígia Castanheira, Ana M. Sebastião, Diogo Telles-Correia
Publicado en: Current Topics in Medicinal Chemistry, Edición 18/19, 2018, Página(s) 1677-1703, ISSN 1568-0266
Editor: Bentham Science Publishers
DOI: 10.2174/1568026618666181115095920

Hippocampal GABAergic transmission: a new target for adenosine control of excitability

Autores: Diogo M. Rombo, Joaquim A. Ribeiro, Ana M. Sebastião
Publicado en: Journal of Neurochemistry, Edición 139/6, 2016, Página(s) 1056-1070, ISSN 0022-3042
Editor: Blackwell Publishing Inc.
DOI: 10.1111/jnc.13872

Rare Variants in PLD3 Do Not Affect Risk for Early-Onset Alzheimer Disease in a European Consortium Cohort

Autores: Rita Cacace, Tobi Van den Bossche, Sebastiaan Engelborghs, Nathalie Geerts, Annelies Laureys, Lubina Dillen, Caroline Graff, Håkan Thonberg, Huei-Hsin Chiang, Pau Pastor, Sara Ortega-Cubero, Maria A. Pastor, Janine Diehl-Schmid, Panagiotis Alexopoulos, Luisa Benussi, Roberta Ghidoni, Giuliano Binetti, Benedetta Nacmias, Sandro Sorbi, Raquel Sanchez-Valle, Albert Lladó, Ellen Gelpi, Maria Rosário Almeida, Isabel Santana, Magda Tsolaki, Maria Koutroumani, Jordi Clarimon, Alberto Lleó, Juan Fortea, Alexandre de Mendonça, Madalena Martins, Barbara Borroni, Alessandro Padovani, Radoslav Matej, Zdenek Rohan, Mathieu Vandenbulcke, Rik Vandenberghe, Peter P. De Deyn, Patrick Cras, Julie van der Zee, Kristel Sleegers, Christine Van Broeckhoven
Publicado en: Human Mutation, Edición 10597794, 2015, Página(s) 1226-1235, ISSN 1059-7794
Editor: John Wiley & Sons Inc.
DOI: 10.1002/humu.22908

BDNF, via truncated TrkB receptor, modulates GlyT1 and GlyT2 in astrocytes

Autores: Rita I. Aroeira, Ana M. Sebastião, Cláudia A. Valente
Publicado en: Glia, Edición 08941491, 2015, Página(s) 2181-2197, ISSN 0894-1491
Editor: John Wiley & Sons Inc.
DOI: 10.1002/glia.22884

Adenosine A2A receptor activation is determinant for BDNF actions upon GABA and glutamate release from rat hippocampal synaptosomes

Autores: Sandra Henriques Vaz, Sofia Rapaz Lérias, Sara Parreira, Maria José Diógenes, Ana Maria Sebastião
Publicado en: Purinergic Signalling, Edición 15739538, 2015, Página(s) 607-612, ISSN 1573-9538
Editor: Springer Verlag
DOI: 10.1007/s11302-015-9476-1

Do We Have a Channel Solution for ALS?

Autores: Mamede de Carvalho
Publicado en: EBioMedicine, Edición 23523964, 2015, Página(s) 1842-1843, ISSN 2352-3964
Editor: Elsevier BV
DOI: 10.1016/j.ebiom.2015.12.002

Tracking motor neuron loss in a set of six muscles in amyotrophic lateral sclerosis using the Motor Unit Number Index (MUNIX): a 15-month longitudinal multicentre trial

Autores: Christoph Neuwirth, Paul E Barkhaus, Christian Burkhardt, José Castro, David Czell, Mamede de Carvalho, Sanjeev Nandedkar, Erik Stålberg, Markus Weber
Publicado en: Journal of Neurology, Neurosurgery & Psychiatry, Edición 00223050, 2015, Página(s) 1172-1179, ISSN 0022-3050
Editor: BMJ Publishing Group
DOI: 10.1136/jnnp-2015-310509

Presymptomatic and symptomatic ALS SOD1(G93A) mice differ in adenosine A1 and A2A receptor-mediated tonic modulation of neuromuscular transmission

Autores: Filipe Nascimento, Ana M. Sebastião, Joaquim A. Ribeiro
Publicado en: Purinergic Signalling, Edición 15739538, 2015, Página(s) 471-480, ISSN 1573-9538
Editor: Springer Verlag
DOI: 10.1007/s11302-015-9465-4

Neuromodulation and metamodulation by adenosine: Impact and subtleties upon synaptic plasticity regulation

Autores: Ana M. Sebastião, Joaquim A. Ribeiro
Publicado en: Brain Research, Edición 00068993, 2015, Página(s) 102-113, ISSN 0006-8993
Editor: Elsevier BV
DOI: 10.1016/j.brainres.2014.11.008

Prognostic models based on patient snapshots and time windows: Predicting disease progression to assisted ventilation in Amyotrophic Lateral Sclerosis

Autores: André V. Carreiro, Pedro M.T. Amaral, Susana Pinto, Pedro Tomás, Mamede de Carvalho, Sara C. Madeira
Publicado en: Journal of Biomedical Informatics, Edición 15320464, 2015, Página(s) 133-144, ISSN 1532-0464
Editor: Academic Press
DOI: 10.1016/j.jbi.2015.09.021

Brain-derived neurotrophic factor mediates neuroprotection against A β -induced toxicity through a mechanism independent on adenosine 2A receptor activation

Autores: André Jerónimo-Santos, João Fonseca-Gomes, Diogo Andrade Guimarães, Sara Ramalho Tanqueiro, Rita Mira Ramalho, Joaquim Alexandre Ribeiro, Ana Maria Sebastião, Maria José Diógenes
Publicado en: Growth Factors, Edición 08977194, 2015, Página(s) 298-308, ISSN 0897-7194
Editor: Taylor & Francis
DOI: 10.3109/08977194.2015.1080696

Integrative biomarker discovery in neurodegenerative diseases

Autores: André V. Carreiro, Alexandre Mendonça, Mamede de Carvalho, Sara C. Madeira
Publicado en: Wiley Interdisciplinary Reviews: Systems Biology and Medicine, Edición 19395094, 2015, Página(s) 357-379, ISSN 1939-5094
Editor: John Wiley and Sons Inc.
DOI: 10.1002/wsbm.1310

Decrease in APP and CP mRNA expression supports impairment of iron export in Alzheimer's disease patients

Autores: Cláudia Guerreiro, Bruno Silva, Ângela C. Crespo, Liliana Marques, Sónia Costa, Ângela Timóteo, Erica Marcelino, Carolina Maruta, Arminda Vilares, Mafalda Matos, Frederico Simões Couto, Paula Faustino, Ana Verdelho, Manuela Guerreiro, Ana Herrero, Cristina Costa, Alexandre de Mendonça, Madalena Martins, Luciana Costa
Publicado en: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Edición 09254439, 2015, Página(s) 2116-2122, ISSN 0925-4439
Editor: Elsevier BV
DOI: 10.1016/j.bbadis.2015.07.017

Purine nucleosides in neuroregeneration and neuroprotection

Autores: Filipa F. Ribeiro, Sara Xapelli, Catarina Miranda-Lourenço, Sara R. Tanqueiro, João Fonseca-Gomes, Maria J. Diógenes, Joaquim A. Ribeiro, Ana M. Sebastião
Publicado en: Neuropharmacology, Edición 00283908, 2015, ISSN 0028-3908
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2015.11.006

Neural commitment of human pluripotent stem cells under defined conditions recapitulates neural development and generates patient-specific neural cells

Autores: Tiago G. Fernandes, Sofia T. Duarte, Mehrnaz Ghazvini, Cláudia Gaspar, Diana C. Santos, Ana R. Porteira, Gonçalo M. C. Rodrigues, Simone Haupt, Diogo M. Rombo, Judith Armstrong, Ana M. Sebastião, Joost Gribnau, Àngels Garcia-Cazorla, Oliver Brüstle, Domingos Henrique, Joaquim M. S. Cabral, Maria Margarida Diogo
Publicado en: Biotechnology Journal, Edición 18606768, 2015, Página(s) 1578-1588, ISSN 1860-6768
Editor: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/biot.201400751

Adenosine A2A Receptors Modulate α-Synuclein Aggregation and Toxicity

Autores: Ferreira DG, Batalha VL, Vicente Miranda H, Coelho JE, Gomes R, Gonçalves FQ, Real JI, Rino J, Albino-Teixeira A, Cunha RA, Outeiro TF, Lopes LV
Publicado en: Cereb Cortex. 2015 Nov 2. pii: bhv268, 2015, ISSN 1460-2199
Editor: Oxford Journals

Dysregulation of TrkB Receptors and BDNF Function by Amyloid-β Peptide is Mediated by Calpain

Autores: André Jerónimo-Santos, Sandra Henriques Vaz, Sara Parreira, Sofia Rapaz-Lérias, António P. Caetano, Valérie Buée-Scherrer, Eero Castrén, Claudia A. Valente, David Blum, Ana Maria Sebastião, Maria José Diógenes
Publicado en: Cerebral Cortex, Edición 10473211, 2015, Página(s) 3107-3121, ISSN 1047-3211
Editor: Oxford University Press
DOI: 10.1093/cercor/bhu105

Axonal elongation and dendritic branching is enhanced by adenosine A2A receptors activation in cerebral cortical neurons

Autores: Ribeiro FF, Neves-Tomé R, Assaife-Lopes N, Santos TE, Silva RF, Brites D, Ribeiro JA, Sousa MM, Sebastião AM.
Publicado en: Brain Struct Funct. 2015 Jun 12, 2015, ISSN 1863-2661
Editor: Springer-Verlag Berlin Heidelberg 2015

Predicting clinical response in people at ultra-high risk of psychosis: a systematic and quantitative review

Autores: Andrea Mechelli, Diana Prata, Charles Kefford, Shitij Kapur
Publicado en: Drug Discovery Today, Edición 13596446, 2015, Página(s) 924-927, ISSN 1359-6446
Editor: Elsevier BV
DOI: 10.1016/j.drudis.2015.03.003

Comment on: The Awaji criteria are not always superior to the previous criteria: A meta-analysis

Autores: Mamede de Carvalho, João Costa, Michael Swash
Publicado en: Muscle & Nerve, Edición 0148639X, 2015, Página(s) 467-468, ISSN 0148-639X
Editor: John Wiley & Sons Inc.
DOI: 10.1002/mus.24734

Ensuring continued progress in biomarkers for amyotrophic lateral sclerosis: Another view

Autores: Mamede de Carvalho
Publicado en: Muscle & Nerve, Edición 0148639X, 2015, Página(s) 460-461, ISSN 0148-639X
Editor: John Wiley & Sons Inc.
DOI: 10.1002/mus.24517

The R of ALSFRS-R: Does it really mirror functional respiratory involvement in amyotrophic lateral sclerosis?

Autores: Susana Pinto, Mamede de Carvalho
Publicado en: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Edición 21678421, 2014, Página(s) 120-123, ISSN 2167-8421
Editor: Informa Healthcare
DOI: 10.3109/21678421.2014.952641

The giant miniature endplate potentials frequency is increased in aged rats

Autores: Paula A. Pousinha, Alexandra M. Correia, Ana M. Sebastião, Joaquim A. Ribeiro
Publicado en: Neuroscience Letters, Edición 03043940, 2015, Página(s) 224-229, ISSN 0304-3940
Editor: Elsevier BV
DOI: 10.1016/j.neulet.2014.10.035

Tackling diagnostic delays in ALS

Autores: Mamede de Carvalho
Publicado en: The Lancet Neurology, Edición 14744422, 2015, Página(s) 457-458, ISSN 1474-4422
Editor: The Lancet Publishing Group
DOI: 10.1016/S1474-4422(15)00020-4

Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

Autores: Axel Freischmidt, Thomas Wieland, Benjamin Richter, Wolfgang Ruf, Veronique Schaeffer, Kathrin Müller, Nicolai Marroquin, Frida Nordin, Annemarie Hübers, Patrick Weydt, Susana Pinto, Rayomond Press, Stéphanie Millecamps, Nicolas Molko, Emilien Bernard, Claude Desnuelle, Marie-Hélène Soriani, Johannes Dorst, Elisabeth Graf, Ulrika Nordström, Marisa S Feiler, Stefan Putz, Tobias M Boeckers, Thomas Meyer, Andrea S Winkler, Juliane Winkelman, Mamede de Carvalho, Dietmar R Thal, Markus Otto, Thomas Brännström, Alexander E Volk, Petri Kursula, Karin M Danzer, Peter Lichtner, Ivan Dikic, Thomas Meitinger, Albert C Ludolph, Tim M Strom, Peter M Andersen, Jochen H Weishaupt
Publicado en: Nature Neuroscience, Edición 10976256, 2015, Página(s) 631-636, ISSN 1097-6256
Editor: Nature Publishing Group
DOI: 10.1038/nn.4000

Changes in corticostriatal connectivity during reinforcement learning in humans

Autores: Guillermo Horga, Tiago V. Maia, Rachel Marsh, Xuejun Hao, Dongrong Xu, Yunsuo Duan, Gregory Z. Tau, Barbara Graniello, Zhishun Wang, Alayar Kangarlu, Diana Martinez, Mark G. Packard, Bradley S. Peterson
Publicado en: Human Brain Mapping, Edición 10659471, 2015, Página(s) 793-803, ISSN 1065-9471
Editor: John Wiley & Sons Inc.
DOI: 10.1002/hbm.22665

MicroRNA-34a Modulates Neural Stem Cell Differentiation by Regulating Expression of Synaptic and Autophagic Proteins

Autores: Ana L. Morgado, Joana M. Xavier, Pedro A. Dionísio, Maria F. C. Ribeiro, Raquel B. Dias, Ana M. Sebastião, Susana Solá, Cecília M. P. Rodrigues
Publicado en: Molecular Neurobiology, Edición 08937648, 2015, Página(s) 1168-1183, ISSN 0893-7648
Editor: Humana Press, Inc.
DOI: 10.1007/s12035-014-8794-6

Synaptic mechanisms of adenosine A 2A receptor-mediated hyperexcitability in the hippocampus

Autores: Diogo M. Rombo, Kathryn Newton, Wiebke Nissen, Sylvia Badurek, Jacqueline M. Horn, Liliana Minichiello, John G.R. Jefferys, Ana M. Sebastiao, Karri P. Lamsa
Publicado en: Hippocampus, Edición 10509631, 2015, Página(s) 566-580, ISSN 1050-9631
Editor: John Wiley & Sons Inc.
DOI: 10.1002/hipo.22392

The Combined Inhibitory Effect of the Adenosine A 1 and Cannabinoid CB 1 Receptors on cAMP Accumulation in the Hippocampus Is Additive and Independent of A 1 Receptor Desensitization

Autores: André Serpa, Sara Correia, Joaquim A. Ribeiro, Ana M. Sebastião, José F. Cascalheira
Publicado en: BioMed Research International, Edición 23146133, 2015, Página(s) 1-9, ISSN 2314-6133
Editor: Hindawi Publishing Corporation
DOI: 10.1155/2015/872684

Non-literal language deficits in mild cognitive impairment

Autores: Sandra Cardoso, Dina Silva, João Maroco, Alexandre de Mendonça, Manuela Guerreiro
Publicado en: Psychogeriatrics, Edición 13463500, 2014, Página(s) 222-228, ISSN 1346-3500
Editor: Blackwell Publishing Inc.
DOI: 10.1111/psyg.12101

Neuroinflammation after neonatal hypoxia–ischemia is associated with alterations in the purinergic system: adenosine deaminase 1 isoenzyme is the most predominant after insult

Autores: Victor Camera Pimentel, Maria Beatriz Moretto, Mariana Colino Oliveira, Daniela Zanini, Ana Maria Sebastião, Maria Rosa Chitolina Schetinger
Publicado en: Molecular and Cellular Biochemistry, Edición 03008177, 2015, Página(s) 169-177, ISSN 0300-8177
Editor: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s11010-015-2347-9

Genetic variability in SQSTM1 and risk of early-onset Alzheimer dementia: a European early-onset dementia consortium study

Autores: Elise Cuyvers, Julie van der Zee, Karolien Bettens, Sebastiaan Engelborghs, Mathieu Vandenbulcke, Caroline Robberecht, Lubina Dillen, Céline Merlin, Nathalie Geerts, Caroline Graff, Håkan Thonberg, Huei-Hsin Chiang, Pau Pastor, Sara Ortega-Cubero, Maria A. Pastor, Janine Diehl-Schmid, Panagiotis Alexopoulos, Luisa Benussi, Roberta Ghidoni, Giuliano Binetti, Benedetta Nacmias, Sandro Sorbi, Raquel Sanchez-Valle, Albert Lladó, Ellen Gelpi, Maria Rosário Almeida, Isabel Santana, Jordi Clarimon, Alberto Lleó, Juan Fortea, Alexandre de Mendonça, Madalena Martins, Barbara Borroni, Alessandro Padovani, Radoslav Matěj, Zdenek Rohan, Agustín Ruiz, Giovanni B. Frisoni, Gian Maria Fabrizi, Rik Vandenberghe, Peter P. De Deyn, Christine Van Broeckhoven, Kristel Sleegers
Publicado en: Neurobiology of Aging, Edición 01974580, 2015, Página(s) 2005.e15-2005.e22, ISSN 0197-4580
Editor: Elsevier BV
DOI: 10.1016/j.neurobiolaging.2015.02.014

Prevalence and prognosis of Alzheimer’s disease at the mild cognitive impairment stage

Autores: Stephanie J. B. Vos, Frans Verhey, Lutz Frölich, Johannes Kornhuber, Jens Wiltfang, Wolfgang Maier, Oliver Peters, Eckart Rüther, Flavio Nobili, Silvia Morbelli, Giovanni B. Frisoni, Alexander Drzezga, Mira Didic, Bart N. M. van Berckel, Andrew Simmons, Hilkka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Simon Lovestone, Cristina Muscio, Sanna-Kaisa Herukka, Eric Salmon, Christine Bastin, Anders Wallin, Arto Nordlund, Alexandre de Mendonça, Dina Silva, Isabel Santana, Raquel Lemos, Sebastiaan Engelborghs, Stefan Van der Mussele, Yvonne Freund-Levi, Åsa K. Wallin, Harald Hampel, Wiesje van der Flier, Philip Scheltens, Pieter Jelle Visser
Publicado en: Brain, Edición 00068950, 2015, Página(s) 1327-1338, ISSN 0006-8950
Editor: Oxford University Press
DOI: 10.1093/brain/awv029

Phosphoneurofilament heavy chain and N-glycomics from the cerebrospinal fluid in amyotrophic lateral sclerosis

Autores: Margarida Gonçalves, Linda Tillack, Mamede de Carvalho, Susana Pinto, Harald S. Conradt, Júlia Costa
Publicado en: Clinica Chimica Acta, Edición 00098981, 2015, Página(s) 342-349, ISSN 0009-8981
Editor: Elsevier BV
DOI: 10.1016/j.cca.2014.09.011

Ultrasound in ALS: Is it a sound method?

Autores: Mamede de Carvalho
Publicado en: Clinical Neurophysiology, Edición 13882457, 2015, Página(s) 651-652, ISSN 1388-2457
Editor: Elsevier BV
DOI: 10.1016/j.clinph.2014.08.002

Differential Role of the Proteasome in the Early and Late Phases of BDNF-Induced Facilitation of LTP

Autores: A. R. Santos, M. Mele, S. H. Vaz, B. Kellermayer, M. Grimaldi, M. Colino-Oliveira, D. M. Rombo, D. Comprido, A. M. Sebastiao, C. B. Duarte
Publicado en: Journal of Neuroscience, Edición 02706474, 2015, Página(s) 3319-3329, ISSN 0270-6474
Editor: Society for Neuroscience
DOI: 10.1523/JNEUROSCI.4521-14.2015

Classification of primary progressive aphasia: Do unsupervised data mining methods support a logopenic variant?

Autores: Carolina Maruta, Telma Pereira, Sara C. Madeira, Alexandre De Mendonça, Manuela Guerreiro
Publicado en: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Edición 21678421, 2015, Página(s) 147-159, ISSN 2167-8421
Editor: Informa Healthcare
DOI: 10.3109/21678421.2015.1026266

The use of biomarkers for the etiologic diagnosis of MCI in Europe: An EADC survey

Autores: Martina Bocchetta, Samantha Galluzzi, Patrick Gavin Kehoe, Eduardo Aguera, Roberto Bernabei, Roger Bullock, Mathieu Ceccaldi, Jean-François Dartigues, Alexandre de Mendonça, Mira Didic, Maria Eriksdotter, Olivier Félician, Lutz Frölich, Hermann-Josef Gertz, Merja Hallikainen, Steen G. Hasselbalch, Lucrezia Hausner, Isabell Heuser, Frank Jessen, Roy W. Jones, Alexander Kurz, Brian Lawlor, Alberto Lleo, Pablo Martinez-Lage, Patrizia Mecocci, Shima Mehrabian, Andreas Monsch, Flavio Nobili, Agneta Nordberg, Marcel Olde Rikkert, Jean-Marc Orgogozo, Florence Pasquier, Oliver Peters, Eric Salmon, Carmen Sánchez-Castellano, Isabel Santana, Marie Sarazin, Latchezar Traykov, Magda Tsolaki, Pieter Jelle Visser, Åsa K. Wallin, Gordon Wilcock, David Wilkinson, Henrike Wolf, Görsev Yener, Dina Zekry, Giovanni B. Frisoni
Publicado en: Alzheimer's & Dementia, Edición 15525260, 2015, Página(s) 195-206.e1, ISSN 1552-5260
Editor: Elsevier BV
DOI: 10.1016/j.jalz.2014.06.006

Significance of Subjective Memory Complaints in the Clinical Setting

Autores: D. Silva, M. Guerreiro, C. Faria, J. Maroco, B. A. Schmand, A. d. Mendonca
Publicado en: Journal of Geriatric Psychiatry and Neurology, Edición 08919887, 2014, Página(s) 259-265, ISSN 0891-9887
Editor: SAGE Publications
DOI: 10.1177/0891988714532018

Modulation of cGMP accumulation by adenosine A1 receptors at the hippocampus: Influence of cGMP levels and gender

Autores: André Serpa, Ana M. Sebastião, José F. Cascalheira
Publicado en: European Journal of Pharmacology, Edición 00142999, 2014, Página(s) 83-90, ISSN 0014-2999
Editor: Elsevier BV
DOI: 10.1016/j.ejphar.2014.09.045

Endogenous inhibition of hippocampal LTD and depotentiation by vasoactive intestinal peptide VPAC 1 receptors

Autores: Diana Cunha-Reis, Maria de Fatima Aidil-Carvalho, Joaquim A. Ribeiro
Publicado en: Hippocampus, Edición 10509631, 2014, Página(s) 1353-1363, ISSN 1050-9631
Editor: John Wiley & Sons Inc.
DOI: 10.1002/hipo.22316

Young slow-progressing ALS patients are at higher risk of inappropriate and disease-quickening surgeries

Autores: Susana Pinto, Mamede de Carvalho
Publicado en: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Edición 21678421, 2014, Página(s) 621-621, ISSN 2167-8421
Editor: Informa Healthcare
DOI: 10.3109/21678421.2014.948881

Maternal separation impairs long term-potentiation in CA1-CA3 synapses and hippocampal-dependent memory in old rats

Autores: Vasco C. Sousa, Joana Vital, Ana Rita Costenla, Vânia L. Batalha, Ana M. Sebastião, Joaquim A. Ribeiro, Luísa V. Lopes
Publicado en: Neurobiology of Aging, Edición 01974580, 2014, Página(s) 1680-1685, ISSN 0197-4580
Editor: Elsevier BV
DOI: 10.1016/j.neurobiolaging.2014.01.024

Does surgery accelerate progression of amyotrophic lateral sclerosis?

Autores: S. Pinto, M. Swash, M. de Carvalho
Publicado en: Journal of Neurology, Neurosurgery & Psychiatry, Edición 00223050, 2014, Página(s) 643-646, ISSN 0022-3050
Editor: BMJ Publishing Group
DOI: 10.1136/jnnp-2013-305770

Adenosine A2A Receptors Activation Facilitates Neuromuscular Transmission in the Pre-Symptomatic Phase of the SOD1(G93A) ALS Mice, but Not in the Symptomatic Phase

Autores: Filipe Nascimento, Paula A. Pousinha, Alexandra M. Correia, Rui Gomes, Ana M. Sebastião, Joaquim A. Ribeiro
Publicado en: PLoS ONE, Edición 19326203, 2014, Página(s) e104081, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0104081

Impact of in vivo chronic blockade of adenosine A2A receptors on the BDNF-mediated facilitation of LTP

Autores: André Jerónimo-Santos, Vânia L. Batalha, Christa E. Müller, Younis Baqi, Ana Maria Sebastião, Luisa V. Lopes, Maria José Diógenes
Publicado en: Neuropharmacology, Edición 00283908, 2014, Página(s) 99-106, ISSN 0028-3908
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2014.04.006

Mechanisms of Regulation of Olfactory Transduction and Adaptation in the Olfactory Cilium

Autores: Gabriela Antunes, Ana Maria Sebastião, Fabio Marques Simoes de Souza
Publicado en: PLoS ONE, Edición 19326203, 2014, Página(s) e105531, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0105531

Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration

Autores: Julie van der Zee, Tim Van Langenhove, Gabor G. Kovacs, Lubina Dillen, William Deschamps, Sebastiaan Engelborghs, Radoslav Matěj, Mathieu Vandenbulcke, Anne Sieben, Bart Dermaut, Katrien Smets, Philip Van Damme, Céline Merlin, Annelies Laureys, Marleen Van Den Broeck, Maria Mattheijssens, Karin Peeters, Luisa Benussi, Giuliano Binetti, Roberta Ghidoni, Barbara Borroni, Alessandro Padovani, Silvana Archetti, Pau Pastor, Cristina Razquin, Sara Ortega-Cubero, Isabel Hernández, Mercè Boada, Agustín Ruiz, Alexandre de Mendonça, Gabriel Miltenberger-Miltényi, Frederico Simões do Couto, Sandro Sorbi, Benedetta Nacmias, Silvia Bagnoli, Caroline Graff, Huei-Hsin Chiang, Håkan Thonberg, Robert Perneczky, Janine Diehl-Schmid, Panagiotis Alexopoulos, Giovanni B. Frisoni, Christian Bonvicini, Matthis Synofzik, Walter Maetzler, Jennifer Müller vom Hagen, Ludger Schöls, Tobias B. Haack, Tim M. Strom, Holger Prokisch, Oriol Dols-Icardo, Jordi Clarimón, Alberto Lleó, Isabel Santana, Maria Rosário Almeida, Beatriz Santiago, Michael T. Heneka, Frank Jessen, Alfredo Ramirez, Raquel Sanchez-Valle, Albert Llado, Ellen Gelpi, Stayko Sarafov, Ivailo Tournev, Albena Jordanova, Eva Parobkova, Gian Maria Fabrizi, Silvia Testi, Eric Salmon, Thomas Ströbel, Patrick Santens, Wim Robberecht, Peter De Jonghe, Jean-Jacques Martin, Patrick Cras, Rik Vandenberghe, Peter Paul De Deyn, Marc Cruts, Kristel Sleegers, Christine Van Broeckhoven
Publicado en: Acta Neuropathologica, Edición 00016322, 2014, Página(s) 397-410, ISSN 0001-6322
Editor: Springer Verlag
DOI: 10.1007/s00401-014-1298-7

Overexpression of Adenosine A2A Receptors in Rats: Effects on Depression, Locomotion, and Anxiety

Autores: Joana E. Coelho, Pedro Alves, Paula M. Canas, Jorge S. Valadas, Tatiana Shmidt, VÃ¢nia L. Batalha, Diana G. Ferreira, Joaquim A. Ribeiro, Michael Bader, Rodrigo A. Cunha, Frederico SimÃµes do Couto, LuÃsa V. Lopes
Publicado en: Frontiers in Psychiatry, Edición 16640640, 2014, ISSN 1664-0640
Editor: Frontiers Research Foundation
DOI: 10.3389/fpsyt.2014.00067

P2Y 1 receptor inhibits GABA transport through a calcium signalling-dependent mechanism in rat cortical astrocytes

Autores: Pedro F. Jacob, Sandra H. Vaz, Joaquim A. Ribeiro, Ana M. Sebastião
Publicado en: Glia, Edición 08941491, 2014, Página(s) 1211-1226, ISSN 0894-1491
Editor: John Wiley & Sons Inc.
DOI: 10.1002/glia.22673

Delayed diagnosis in ALS: The problem continues

Autores: Hipolito Nzwalo, Daisy de Abreu, Michael Swash, Susana Pinto, Mamede de Carvalho
Publicado en: Journal of the Neurological Sciences, Edición 0022510X, 2014, Página(s) 173-175, ISSN 0022-510X
Editor: Elsevier BV
DOI: 10.1016/j.jns.2014.06.003

Multicentre quality control evaluation of different biomarker candidates for amyotrophic lateral sclerosis

Autores: Stefan Lehnert, Julia Costa, Mamede de Carvalho, Janine Kirby, Magdalena Kuzma-Kozakiewicz, Claudia Morelli, Wim Robberecht, Pamela Shaw, Vincenzo Silani, Petra Steinacker, Hayrettin Tumani, Philip Van Damme, Albert Ludolph, Markus Otto
Publicado en: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Edición 21678421, 2014, Página(s) 344-350, ISSN 2167-8421
Editor: Informa Healthcare
DOI: 10.3109/21678421.2014.884592

Modeling the functional network of primary intercellular Ca2+ wave propagation in astrocytes and its application to study drug effects

Autores: Marcelo Pires, Frank Raischel, Sandra H. Vaz, Andreia Cruz-Silva, Ana M. Sebastião, Pedro G. Lind
Publicado en: Journal of Theoretical Biology, Edición 00225193, 2014, Página(s) 201-212, ISSN 0022-5193
Editor: Academic Press
DOI: 10.1016/j.jtbi.2014.04.024

Motoneuron firing in amyotrophic lateral sclerosis (ALS)

Autores: Mamede de Carvalho, Andrew Eisen, Charles Krieger, Michael Swash
Publicado en: Frontiers in Human Neuroscience, Edición 16625161, 2014, ISSN 1662-5161
Editor: Frontiers Research Foundation
DOI: 10.3389/fnhum.2014.00719

Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS)

Autores: Jean-Pascal Lefaucheur, Nathalie André-Obadia, Andrea Antal, Samar S. Ayache, Chris Baeken, David H. Benninger, Roberto M. Cantello, Massimo Cincotta, Mamede de Carvalho, Dirk De Ridder, Hervé Devanne, Vincenzo Di Lazzaro, Saša R. Filipović, Friedhelm C. Hummel, Satu K. Jääskeläinen, Vasilios K. Kimiskidis, Giacomo Koch, Berthold Langguth, Thomas Nyffeler, Antonio Oliviero, Frank Padberg, Emmanuel Poulet, Simone Rossi, Paolo Maria Rossini, John C. Rothwell, Carlos Schönfeldt-Lecuona, Hartwig R. Siebner, Christina W. Slotema, Charlotte J. Stagg, Josep Valls-Sole, Ulf Ziemann, Walter Paulus, Luis Garcia-Larrea
Publicado en: Clinical Neurophysiology, Edición 13882457, 2014, Página(s) 2150-2206, ISSN 1388-2457
Editor: Elsevier BV
DOI: 10.1016/j.clinph.2014.05.021

Neurophysiological techniques to detect early small-fiber dysfunction in transthyretin amyloid polyneuropathy

Autores: Isabel Conceição, João Costa, José Castro, Mamede de Carvalho
Publicado en: Muscle & Nerve, Edición 0148639X, 2014, Página(s) 181-186, ISSN 0148-639X
Editor: John Wiley & Sons Inc.
DOI: 10.1002/mus.23901

Challenges and Promises in the Development of Neurotrophic Factor-Based Therapies for Parkinson’s Disease

Autores: Tiago Martins Rodrigues, André Jerónimo-Santos, Tiago Fleming Outeiro, Ana Maria Sebastião, Maria José Diógenes
Publicado en: Drugs & Aging, Edición 1170229X, 2014, Página(s) 239-261, ISSN 1170-229X
Editor: Adis International Ltd.
DOI: 10.1007/s40266-014-0160-x

Sensitivity of MUP parameters in detecting change in early ALS

Autores: Mamede de Carvalho, Antonia Turkman, Michael Swash
Publicado en: Clinical Neurophysiology, Edición 13882457, 2014, Página(s) 166-169, ISSN 1388-2457
Editor: Elsevier BV
DOI: 10.1016/j.clinph.2013.06.014

A handful of promises

Autores: Mamede de Carvalho
Publicado en: Clinical Neurophysiology, Edición 13882457, 2014, Página(s) 5, ISSN 1388-2457
Editor: Elsevier BV
DOI: 10.1016/j.clinph.2013.08.011

Homeostatic Control of Synaptic Activity by Endogenous Adenosine is Mediated by Adenosine Kinase

Autores: M. J. Diogenes, R. Neves-Tome, S. Fucile, K. Martinello, M. Scianni, P. Theofilas, J. Lopatar, J. A. Ribeiro, L. Maggi, B. G. Frenguelli, C. Limatola, D. Boison, A. M. Sebastiao
Publicado en: Cerebral Cortex, Edición 10473211, 2013, Página(s) 67-80, ISSN 1047-3211
Editor: Oxford University Press
DOI: 10.1093/cercor/bhs284

Breathing new life into treatment advances for respiratory failure in amyotrophic lateral sclerosis patients

Autores: Susana Pinto, Mamede de Carvalho
Publicado en: Neurodegenerative Disease Management, Edición 17582024, 2014, Página(s) 83-102, ISSN 1758-2024
Editor: Future Medicine Ltd.
DOI: 10.2217/nmt.13.74

From epidemiology to pathophysiology: what about caffeine in Alzheimer's disease?

Autores: Vanessa Flaten, Cyril Laurent, Joana E. Coelho, Ursula Sandau, Vânia L. Batalha, Sylvie Burnouf, Malika Hamdane, Sandrine Humez, Detlev Boison, Luísa V. Lopes, Luc Buée, David Blum
Publicado en: Biochemical Society Transactions, Edición 03005127, 2014, Página(s) 587-592, ISSN 0300-5127
Editor: Portland Press, Ltd.
DOI: 10.1042/BST20130229

Modulation of subventricular zone oligodendrogenesis: a role for hemopressin?

Autores: Sara Xapelli, Fabienne Agasse, Sofia Grade, Liliana Bernardino, Filipa F. Ribeiro, Clarissa S. Schitine, Andrea S. Heimann, Emer S. Ferro, Ana M. Sebasti, Ricardo A. De Melo Reis, João O. Malva
Publicado en: Frontiers in Cellular Neuroscience, Edición 16625102, 2014, ISSN 1662-5102
Editor: Frontiers Research Foundation
DOI: 10.3389/fncel.2014.00059

Roles of Vascular Endothelial Growth Factor in Amyotrophic Lateral Sclerosis

Autores: Ana Catarina Pronto-Laborinho, Susana Pinto, Mamede de Carvalho
Publicado en: BioMed Research International, Edición 23146133, 2014, Página(s) 1-24, ISSN 2314-6133
Editor: Hindawi Publishing Corporation
DOI: 10.1155/2014/947513

A blinded international study on the reliability of genetic testing for GGGGCC-repeat expansions in C9orf72 reveals marked differences in results among 14 laboratories

Autores: C. Akimoto, A. E. Volk, M. van Blitterswijk, M. Van den Broeck, C. S. Leblond, S. Lumbroso, W. Camu, B. Neitzel, O. Onodera, W. van Rheenen, S. Pinto, M. Weber, B. Smith, M. Proven, K. Talbot, P. Keagle, A. Chesi, A. Ratti, J. van der Zee, H. Alstermark, A. Birve, D. Calini, A. Nordin, D. C. Tradowsky, W. Just, H. Daoud, S. Angerbauer, M. DeJesus-Hernandez, T. Konno, A. Lloyd-Jani, M. de Carvalho, K. Mouzat, J. E. Landers, J. H. Veldink, V. Silani, A. D. Gitler, C. E. Shaw, G. A. Rouleau, L. H. van den Berg, C. Van Broeckhoven, R. Rademakers, P. M. Andersen, C. Kubisch
Publicado en: Journal of Medical Genetics, Edición 00222593, 2014, Página(s) 419-424, ISSN 0022-2593
Editor: British Medical Association
DOI: 10.1136/jmedgenet-2014-102360

Genetic and biochemical markers in patients with Alzheimer's disease support a concerted systemic iron homeostasis dysregulation

Autores: Ângela C. Crespo, Bruno Silva, Liliana Marques, Erica Marcelino, Carolina Maruta, Sónia Costa, Ângela Timóteo, Arminda Vilares, Frederico Simões Couto, Paula Faustino, Ana Paula Correia, Ana Verdelho, Graça Porto, Manuela Guerreiro, Ana Herrero, Cristina Costa, Alexandre de Mendonça, Luciana Costa, Madalena Martins
Publicado en: Neurobiology of Aging, Edición 01974580, 2014, Página(s) 777-785, ISSN 0197-4580
Editor: Elsevier BV
DOI: 10.1016/j.neurobiolaging.2013.10.078

Adenosine A2A Receptors as novel upstream regulators of BDNF-mediated attenuation of hippocampal Long-Term Depression (LTD)

Autores: Tiago M. Rodrigues, André Jerónimo-Santos, Ana M. Sebastião, Maria José Diógenes
Publicado en: Neuropharmacology, Edición 00283908, 2014, Página(s) 389-398, ISSN 0028-3908
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2013.12.010

Vascular endothelial growth factor and amyotrophic lateral sclerosis: The interplay with exercise and noninvasive ventilation

Autores: Rita Carilho, Mamede de Carvalho, Michael Swash, Susana Pinto, Anabela Pinto, Júlia Costa
Publicado en: Muscle & Nerve, Edición 0148639X, 2014, Página(s) 545-550, ISSN 0148-639X
Editor: John Wiley & Sons Inc.
DOI: 10.1002/mus.23955

GlyT1 and GlyT2 in brain astrocytes: expression, distribution and function

Autores: Rita I. Aroeira, Ana M. Sebastião, Cláudia A. Valente
Publicado en: Brain Structure and Function, Edición 18632653, 2014, Página(s) 817-830, ISSN 1863-2653
Editor: Springer Verlag
DOI: 10.1007/s00429-013-0537-3

Nerve excitabitability and fasciculations

Autores: Mamede de Carvalho
Publicado en: Clinical Neurophysiology, Edición 13882457, 2013, Página(s) 1925, ISSN 1388-2457
Editor: Elsevier BV
DOI: 10.1016/j.clinph.2013.03.022

Quality of life in patients with cognitive impairment: validation of the Quality of Life–Alzheimer's Disease scale in Portugal

Autores: Helena Bárrios, Ana Verdelho, Sofia Narciso, Manuel Gonçalves-Pereira, Rebecca Logsdon, Alexandre de Mendonça
Publicado en: International Psychogeriatrics, Edición 10416102, 2013, Página(s) 1085-1096, ISSN 1041-6102
Editor: Cambridge University Press
DOI: 10.1017/S1041610213000379

A1R–A2AR heteromers coupled to Gs and Gi/0 proteins modulate GABA transport into astrocytes

Autores: Sofia Cristóvão-Ferreira, Gemma Navarro, Marc Brugarolas, Kamil Pérez-Capote, Sandra H. Vaz, Giorgia Fattorini, Fiorenzo Conti, Carmen Lluis, Joaquim A. Ribeiro, Peter J. McCormick, Vicent Casadó, Rafael Franco, Ana M. Sebastião
Publicado en: Purinergic Signalling, Edición 15739538, 2013, Página(s) 433-449, ISSN 1573-9538
Editor: Springer Verlag
DOI: 10.1007/s11302-013-9364-5

Origin of Fasciculations in Amyotrophic Lateral Sclerosis and Benign Fasciculation Syndrome

Autores: Mamede de Carvalho, Michael Swash
Publicado en: JAMA Neurology, Edición 21686149, 2013, ISSN 2168-6149
Editor: American Medical Association
DOI: 10.1001/jamaneurol.2013.4437

Do MCI patients with vitamin B12 deficiency have distinctive cognitive deficits?

Autores: Dina Silva, Ulrike Albers, Isabel Santana, Margarida Vicente, Isabel Martins, Ana Verdelho, Manuela Guerreiro, Alexandre de-Mendonça
Publicado en: BMC Research Notes, Edición 17560500, 2013, Página(s) 357, ISSN 1756-0500
Editor: BioMed Central
DOI: 10.1186/1756-0500-6-357

Reduced Myocardial 123-Iodine Metaiodobenzylguanidine Uptake: A Prognostic Marker in Familial Amyloid Polyneuropathy

Autores: M. C. A. Coutinho, N. Cortez-Dias, G. Cantinho, I. Conceicao, A. Oliveira, A. Bordalo e Sa, S. Goncalves, A. G. Almeida, M. de Carvalho, A. N. Diogo
Publicado en: Circulation: Cardiovascular Imaging, Edición 19419651, 2013, Página(s) 627-636, ISSN 1941-9651
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/CIRCIMAGING.112.000367

Activation of Type 1 Cannabinoid Receptor (CB1R) Promotes Neurogenesis in Murine Subventricular Zone Cell Cultures

Autores: Sara Xapelli, Fabienne Agasse, Laura Sardà-Arroyo, Liliana Bernardino, Tiago Santos, Filipa F. Ribeiro, Jorge Valero, José Bragança, Clarissa Schitine, Ricardo A. de Melo Reis, Ana M. Sebastião, João O. Malva
Publicado en: PLoS ONE, Edición 19326203, 2013, Página(s) e63529, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0063529

Hypoxia–Ischemia Alters Nucleotide and Nucleoside Catabolism and Na+,K+-ATPase Activity in the Cerebral Cortex of Newborn Rats

Autores: Victor Camera Pimentel, Daniela Zanini, Andréia Machado Cardoso, Roberta Schmatz, Margarete Dulce Bagatini, Jessié Martins Gutierres, Fabiano Carvalho, Jéssica Lopes Gomes, Maribel Rubin, Vera Maria Morsch, Maria Beatriz Moretto, Mariana Colino-Oliveira, Ana Maria Sebastião, Maria Rosa Chitolina Schetinger
Publicado en: Neurochemical Research, Edición 03643190, 2013, Página(s) 886-894, ISSN 0364-3190
Editor: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s11064-013-0994-3

No association between VAPB mutations and familial or sporadic ALS in Sweden, Portugal and Iceland

Autores: Caroline Ingre, Susana Pinto, Anna Birve, Rayomand Press, Olof Danielsson, Mamede de Carvalho, Grétar Guđmundsson, Peter M. Andersen
Publicado en: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Edición 21678421, 2013, Página(s) 620-627, ISSN 2167-8421
Editor: Informa Healthcare
DOI: 10.3109/21678421.2013.822515

Adenosine: setting the stage for plasticity

Autores: Raquel B. Dias, Diogo M. Rombo, Joaquim A. Ribeiro, Jeremy M. Henley, Ana M. Sebastião
Publicado en: Trends in Neurosciences, Edición 01662236, 2013, Página(s) 248-257, ISSN 0166-2236
Editor: Elsevier BV
DOI: 10.1016/j.tins.2012.12.003

Early Changes of Neuromuscular Transmission in the SOD1(G93A) Mice Model of ALS Start Long before Motor Symptoms Onset

Autores: Mariana C. Rocha, Paula A. Pousinha, Alexandra M. Correia, Ana M. Sebastião, Joaquim A. Ribeiro
Publicado en: PLoS ONE, Edición 19326203, 2013, Página(s) e73846, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0073846

Controversies and priorities in amyotrophic lateral sclerosis

Autores: Martin R Turner, Orla Hardiman, Michael Benatar, Benjamin R Brooks, Adriano Chio, Mamede de Carvalho, Paul G Ince, Cindy Lin, Robert G Miller, Hiroshi Mitsumoto, Garth Nicholson, John Ravits, Pamela J Shaw, Michael Swash, Kevin Talbot, Bryan J Traynor, Leonard H Van den Berg, Jan H Veldink, Steve Vucic, Matthew C Kiernan
Publicado en: The Lancet Neurology, Edición 14744422, 2013, Página(s) 310-322, ISSN 1474-4422
Editor: The Lancet Publishing Group
DOI: 10.1016/S1474-4422(13)70036-X

Evidence that conditioned avoidance responses are reinforced by positive prediction errors signaled by tonic striatal dopamine

Autores: Patricia A. Dombrowski, Tiago V. Maia, Suelen L. Boschen, Mariza Bortolanza, Etieli Wendler, Rainer K.W. Schwarting, Marcus Lira Brandão, Philip Winn, Charles D. Blaha, Claudio Da Cunha
Publicado en: Behavioural Brain Research, Edición 01664328, 2013, Página(s) 112-119, ISSN 0166-4328
Editor: Elsevier BV
DOI: 10.1016/j.bbr.2012.06.031

Tauroursodeoxycholic acid suppresses amyloid β-induced synaptic toxicity in vitro and in APP/PS1 mice

Autores: Rita M. Ramalho, Ana F. Nunes, Raquel B. Dias, Joana D. Amaral, Adrian C. Lo, Rudi D'Hooge, Ana M. Sebastião, Cecilia M.P. Rodrigues
Publicado en: Neurobiology of Aging, Edición 01974580, 2013, Página(s) 551-561, ISSN 0197-4580
Editor: Elsevier BV
DOI: 10.1016/j.neurobiolaging.2012.04.018

Split-hand to diagnosis shot

Autores: Mamede de Carvalho
Publicado en: Clinical Neurophysiology, Edición 13882457, 2013, Página(s) 219-220, ISSN 1388-2457
Editor: Elsevier BV
DOI: 10.1016/j.clinph.2012.08.015

A Pan-European Study of the C9orf72 Repeat Associated with FTLD: Geographic Prevalence, Genomic Instability, and Intermediate Repeats

Autores: Julie van der Zee, Ilse Gijselinck, Lubina Dillen, Tim Van Langenhove, Jessie Theuns, Sebastiaan Engelborghs, Stéphanie Philtjens, Mathieu Vandenbulcke, Kristel Sleegers, Anne Sieben, Veerle Bäumer, Githa Maes, Ellen Corsmit, Barbara Borroni, Alessandro Padovani, Silvana Archetti, Robert Perneczky, Janine Diehl-Schmid, Alexandre de Mendonça, Gabriel Miltenberger-Miltenyi, Sónia Pereira, José Pimentel, Benedetta Nacmias, Silvia Bagnoli, Sandro Sorbi, Caroline Graff, Huei-Hsin Chiang, Marie Westerlund, Raquel Sanchez-Valle, Albert Llado, Ellen Gelpi, Isabel Santana, Maria Rosário Almeida, Beatriz Santiago, Giovanni Frisoni, Orazio Zanetti, Cristian Bonvicini, Matthis Synofzik, Walter Maetzler, Jennifer Müller vom Hagen, Ludger Schöls, Michael T. Heneka, Frank Jessen, Radoslav Matej, Eva Parobkova, Gabor G. Kovacs, Thomas Ströbel, Stayko Sarafov, Ivailo Tournev, Albena Jordanova, Adrian Danek, Thomas Arzberger, Gian Maria Fabrizi, Silvia Testi, Eric Salmon, Patrick Santens, Jean-Jacques Martin, Patrick Cras, Rik Vandenberghe, Peter Paul De Deyn, Marc Cruts, Christine Van Broeckhoven, Julie van der Zee, Ilse Gijselinck, Lubina Dillen, Tim Van Langenhove, Jessie Theuns, Stéphanie Philtjens, Kristel Sleegers, Veerle Bäumer, Githa Maes, Ellen Corsmit, Marc Cruts, Christine Van Broeckhoven, Julie van der Zee, Ilse Gijselinck, Lubina Dillen, Tim Van Langenhove, Stéphanie Philtjens, Jessie Theuns, Kristel Sleegers, Veerle Bäumer, Githa Maes, Marc Cruts, Christine Van Broeckhoven, Sebastiaan Engelborghs, Peter P. De Deyn, Patrick Cras, Sebastiaan Engelborghs, Peter P. De Deyn, Mathieu Vandenbulcke, Mathieu Vandenbulcke, Barbara Borroni, Alessandro Padovani, Silvana Archetti, Robert Perneczky, Janine Diehl-Schmid, Matthis Synofzik, Walter Maetzler, Jennifer Müller vom Hagen, Ludger Schöls, Matthis Synofzik, Walter Maetzler, Jennifer Müller vom Hagen, Ludger Schöls, Michael T. Heneka, Frank Jessen, Alfredo Ramirez, Delia Kurzwelly, Carmen Sachtleben, Wolfgang Mairer, Alexandre de Mendonça, Gabriel Miltenberger-Miltenyi, Sónia Pereira, Clara Firmo, José Pimentel, Raquel Sanchez-Valle, Albert Llado, Anna Antonell, Jose Molinuevo, Ellen Gelpi, Caroline Graff, Huei-Hsin Chiang, Marie Westerlund, Caroline Graff, Anne Kinhult Ståhlbom, Håkan Thonberg, Inger Nennesmo, Anne Börjesson-Hanson, Benedetta Nacmias, Silvia Bagnoli, Sandro Sorbi, Valentina Bessi, Irene Piaceri, Isabel Santana, Beatriz Santiago, Isabel Santana, Maria Helena Ribeiro, Maria Rosário Almeida, Catarina Oliveira, João Massano, Carolina Garret, Paula Pires, Giovanni Frisoni, Orazio Zanetti, Cristian Bonvicini, Stayko Sarafov, Ivailo Tournev, Albena Jordanova, Ivailo Tournev, Gabor G. Kovacs, Thomas Ströbel, Michael T. Heneka, Frank Jessen, Alfredo Ramirez, Delia Kurzwelly, Carmen Sachtleben, Wolfgang Mairer, Frank Jessen, Radoslav Matej, Eva Parobkova, Adrian Danel, Thomas Arzberger, Gian Maria Fabrizi, Silvia Testi, Sergio Ferrari, Tiziana Cavallaro, Eric Salmon, Patrick Santens, Patrick Cras
Publicado en: Human Mutation, Edición 10597794, 2013, Página(s) 363-373, ISSN 1059-7794
Editor: John Wiley & Sons Inc.
DOI: 10.1002/humu.22244

Ischemia-induced synaptic plasticity drives sustained expression of calcium-permeable AMPA receptors in the hippocampus

Autores: Raquel B. Dias, Diogo M. Rombo, Joaquim A. Ribeiro, Ana M. Sebastião
Publicado en: Neuropharmacology, Edición 00283908, 2013, Página(s) 114-122, ISSN 0028-3908
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2012.09.016

Lipid rafts, synaptic transmission and plasticity: Impact in age-related neurodegenerative diseases

Autores: Ana M. Sebastião, Mariana Colino-Oliveira, Natália Assaife-Lopes, Raquel B. Dias, Joaquim A. Ribeiro
Publicado en: Neuropharmacology, Edición 00283908, 2013, Página(s) 97-107, ISSN 0028-3908
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2012.06.053

Rapidly progressive frontotemporal dementia and bulbar amyotrophic lateral sclerosis in Portuguese patients with C9orf72 mutation

Autores: Catarina Chester, Mamede de Carvalho, Gabriel Miltenberger, Sónia Pereira, Lubina Dillen, Julie van der Zee, Christine van Broeckhoven, Alexandre de Mendonça
Publicado en: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, Edición 21678421, 2013, Página(s) 70-72, ISSN 2167-8421
Editor: Informa Healthcare
DOI: 10.3109/17482968.2012.690418

Orofacial Apraxia in Motor Neuron Disease

Autores: Patrícia Pita Lobo, Susana Pinto, Luz Rocha, Sofia Reimão, Mamede de Carvalho
Publicado en: Case Reports in Neurology, Edición 1662680X, 2013, Página(s) 47-51, ISSN 1662-680X
Editor: S. Karger AG
DOI: 10.1159/000349895

Phenotypic variability of familial and sporadic Progranulin p.Gln257Profs*27 mutation

Autores: Pires C, Coelho M, Valadas A, Barroso C, Pimentel J, Martins M, Duyckaerts C, de Mendonça A, Verdelho A, Miltenberger-Miltenyi G
Publicado en: J Alzheimers Dis. 2013;37(2):335-42, Edición 18758908, 2013, ISSN 1875-8908
Editor: IOS Press
DOI: 10.3233/JAD-130146

Quality of life in patients with mild cognitive impairment

Autores: Helena Bárrios, Sofia Narciso, Manuela Guerreiro, João Maroco, Rebecca Logsdon, Alexandre de Mendonça
Publicado en: Aging & Mental Health, Edición 13607863, 2013, Página(s) 287-292, ISSN 1360-7863
Editor: Carfax Publishers
DOI: 10.1080/13607863.2012.747083

Prediction of long-term (5 years) conversion to dementia using neuropsychological tests in a memory clinic setting

Autores: Silva D, Guerreiro M, Santana I, Rodrigues A, Cardoso S, Maroco J, de Mendonça A.
Publicado en: J Alzheimers Dis. 2013;34(3):681-9, Edición 18758908, 2013, ISSN 1875-8908
Editor: IOS Press
DOI: 10.3233/JAD-122098

Regulation of TrkB receptor translocation to lipid rafts by adenosine A2A receptors and its functional implications for BDNF-induced regulation of synaptic plasticity

Autores: Natália Assaife-Lopes, Vasco C. Sousa, Daniela B. Pereira, Joaquim A. Ribeiro, Ana M. Sebastião
Publicado en: Purinergic Signalling, Edición 15739538, 2014, Página(s) 251-267, ISSN 1573-9538
Editor: Springer Verlag
DOI: 10.1007/s11302-013-9383-2

Role of Adenosine Receptors in Epileptic Seizures

Autores: Diogo Miguel Rombo, Joaquim Alexandre Ribeiro, Ana Maria Sebastião
Publicado en: The Adenosine Receptors, 2018, Página(s) 309-350, ISBN 978-3-319-90807-6
Editor: Springer International Publishing
DOI: 10.1007/978-3-319-90808-3_13

Neurologic complications of craniovertebral dislocation

Autores: Mamede de Carvalho, Michael Swash
Publicado en: Neurologic Aspects of Systemic Disease Part I, 2014, Página(s) 435-448, ISBN 9780702040863
Editor: Elsevier
DOI: 10.1016/B978-0-7020-4086-3.00028-X

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