Livrables
Report of the external Ethical Advisory Board Report as requested for the Ethical Check
Experimental results. Issue 2T3.2 Sleep (IFADO, UMI, STA): We will explore if lucid dreaming, which is a unique consciousness model in which primary consciousness – normally present during sleep – is transferred to the secondary mode of consciousness, is associated with specific FC alterations beyond regional prefrontal changes as demonstrated recently (Voss2014). We will systematically modulate connectivity to explore if these physiological processes are causally related to lucidity and to which degree specific FC patterns (frequency bands, synchrony) contribute. Oscillatory activity and connectivity will be studied with the advanced EEG models developed in WP1, and interventional stimulation will be performed. We will monitor sleep-dependent alterations of oscillatory activity with specific relation to FC alterations depending on relaxed wakefulness, drowsiness, light sleep, deep slow wave sleep, and REM-sleep in healthy subjects. The results will provide the basis for testing causality via tCS. We will explore consciousness modulation in healthy subjects as well as in patients suffering from sleep disturbance syndromes, i.e., psychophysiological insomnia states, and narcolepsy. The results of this study will elucidate how states of consciousness can be modulated by NIBS, and whether/how pathological alterations of state changes can be counteracted [IFADO]. PCI-based experiments will be conducted on healthy sleeping subjects in order to find the optimal stimulation parameters that are effective in reducing the magnitude and the rate of occurrence of spontaneously occurring and evoked (NIBS, somatosensory, visual, auditory) cortical downstates. It will also allow testing whether tCS, by reducing bistability, may affect the level of consciousness by promoting a sleep stage transition (e.g., from sleep stage N1 to wakefulness, from dreaming to lucid dreaming). [UMI]
Ethical Requirements. Issue 1Ethical Requirements resulting from 2nd iteration of the Ethical Screening during GA preparation.
Experimental plans. Issue 2T3.1 Anaesthesia: (UOX, STA, IFADO, UMI): Apply the concepts/protocols employed during sleep stage N1 or dreaming to subjects who are in a state of mild sedation or during the induction of general anaesthesia (MOOAS level 3) in order to probe the capacity of tCS to (1) alter the EEG features of bistability and (2) shift the level of wakefulness. Explore the relationship of the SWAS biomarker within the information theoretic and PCI approach to consciousness state. We will gather ultra high field 7T resting state fMRI paradigms using the developed EEG metrics as end-points for titration of anaesthesia. In particular we will explore the functional thalamocortical connectivity of the sub-regions of thalamus at these EEG end-points, and identify changes in connectivity induced by tCS. Slow activity is a common feature of both sleep and anaesthesia. There is also evidence that some anaesthetics satisfy the homeostatic need for sleep (Pal2011). By using a within-subject design, we will explore the commonality of these mechanisms further by using EEG recordings of sleep prior to fMRI scanning. We will investigate the effect of tCS on the developed EEG consciousness metrics to elucidate whether the proposed brain interference methods will allow the required dose for anaesthesia-induced loss of consciousness to be reduced, thus reducing the known risks of over-anaesthesia.
Consciousness: models, metrics and intervention. Issue 1T1.1 Neuroscience, Consciousness & Bits (UMI, all): We will review models of consciousness, the relevance of information integration, KAC, bistability, brain rhythms related with consciousness and other explanatory correlates, and study implications for artificial systems and other cognitive sciences. Guide experimental work: specify methods for consciousness characterization, from classical spectral measures to information transfer, connectivity and complex network EEG metrics; explore intrinsic bistability of cortical neurons as a final common pathway leading to a decreased capacity for information integration (indexed by PCI and other metrics) during loss of consciousness; propose how to test hypotheses by studying the effects of different types of perturbations (NIBS, PNS) on EEG recorded during different consciousness conditions; explore the possibility of calculating PCI, or of detecting signs of cortical bistability, starting from stimulation protocols such as tCS and PNS-mediated stimulation (i.e., oddballs, local-global paradigm, subject’s own name); define KAC metrics: 1) using auditory stimuli and study associated functional networks; 2) explore the existence of similar signals using NIBS 3) evaluate tACS perturbation on EEG to create an analogue of sensory ERP. Design techniques to detect the occurrence of perturbation-induced cortical downstates, including period-amplitude analysis of evoked slow waves, time-frequency decomposition and empirical mode decomposition; assess the impact of the downstate on causality at each single recording site by calculating phase-locking factor (Lachaux1999), and the impact of the downstate on causality across recording sites by calculating the phase-locking value (Palva2010). Pre-select appropriate EEG feedback loops in NIBS and guide the EEG feature search (WP2). Finally, organise the 2-3 day yearly project workshops for brainstorming and experimental design. As a final task in the project the experimental results obtained in WP3 will be interpreted and transformed into theoretical advances on consciousness understanding.
Experimental results. Issue 1T3.2 Sleep (IFADO, UMI, STA): We will explore if lucid dreaming, which is a unique consciousness model in which primary consciousness – normally present during sleep – is transferred to the secondary mode of consciousness, is associated with specific FC alterations beyond regional prefrontal changes as demonstrated recently (Voss2014). We will systematically modulate connectivity to explore if these physiological processes are causally related to lucidity and to which degree specific FC patterns (frequency bands, synchrony) contribute. Oscillatory activity and connectivity will be studied with the advanced EEG models developed in WP1, and interventional stimulation will be performed. We will monitor sleep-dependent alterations of oscillatory activity with specific relation to FC alterations depending on relaxed wakefulness, drowsiness, light sleep, deep slow wave sleep, and REM-sleep in healthy subjects. The results will provide the basis for testing causality via tCS. We will explore consciousness modulation in healthy subjects as well as in patients suffering from sleep disturbance syndromes, i.e., psychophysiological insomnia states, and narcolepsy. The results of this study will elucidate how states of consciousness can be modulated by NIBS, and whether/how pathological alterations of state changes can be counteracted [IFADO]. PCI-based experiments will be conducted on healthy sleeping subjects in order to find the optimal stimulation parameters that are effective in reducing the magnitude and the rate of occurrence of spontaneously occurring and evoked (NIBS, somatosensory, visual, auditory) cortical downstates. It will also allow testing whether tCS, by reducing bistability, may affect the level of consciousness by promoting a sleep stage transition (e.g., from sleep stage N1 to wakefulness, from dreaming to lucid dreaming). [UMI]
Ethical implicationsT4.2 Ethics (ULG, all except INS): evaluate project’s S&T socio-ethical implications. Provide open document for wide dissemination and public understanding and for policy makers. Address the impact of potential negative findings of experimental/clinical work and how clinicians and families can deal with them. Analyse next-of-kin verbal reports on how they receive differential diagnosis and NIBS results for their patient, then provide short guides of popularized content addressing to next of kin for psycho-educative purposes on M/EEG assessment and NIBS and guidelines on pragmatic criteria for the differentiation between DOCs – clinical translation of experimental findings. Create and manage a discussion forum on clinical management (pain treatment, treatment limitation) based on the clinical diagnosis delivered by M/EEG measurements and on legal competency of (potentially) recovered patients from NIBS.
Experimental plans. Issue 1T3.1 Anaesthesia: (UOX, STA, IFADO, UMI): Apply the concepts/protocols employed during sleep stage N1 or dreaming to subjects who are in a state of mild sedation or during the induction of general anaesthesia (MOOAS level 3) in order to probe the capacity of tCS to (1) alter the EEG features of bistability and (2) shift the level of wakefulness. Explore the relationship of the SWAS biomarker within the information theoretic and PCI approach to consciousness state. We will gather ultra high field 7T resting state fMRI paradigms using the developed EEG metrics as end-points for titration of anaesthesia. In particular we will explore the functional thalamocortical connectivity of the sub-regions of thalamus at these EEG end-points, and identify changes in connectivity induced by tCS. Slow activity is a common feature of both sleep and anaesthesia. There is also evidence that some anaesthetics satisfy the homeostatic need for sleep (Pal2011). By using a within-subject design, we will explore the commonality of these mechanisms further by using EEG recordings of sleep prior to fMRI scanning. We will investigate the effect of tCS on the developed EEG consciousness metrics to elucidate whether the proposed brain interference methods will allow the required dose for anaesthesia-induced loss of consciousness to be reduced, thus reducing the known risks of over-anaesthesia.
Ethical Advisory BoardTask D4.1 Ethical Advisory Board
Experimental plans. Issue 3T3.1 Anaesthesia: (UOX, STA, IFADO, UMI): Apply the concepts/protocols employed during sleep stage N1 or dreaming to subjects who are in a state of mild sedation or during the induction of general anaesthesia (MOOAS level 3) in order to probe the capacity of tCS to (1) alter the EEG features of bistability and (2) shift the level of wakefulness. Explore the relationship of the SWAS biomarker within the information theoretic and PCI approach to consciousness state. We will gather ultra high field 7T resting state fMRI paradigms using the developed EEG metrics as end-points for titration of anaesthesia. In particular we will explore the functional thalamocortical connectivity of the sub-regions of thalamus at these EEG end-points, and identify changes in connectivity induced by tCS. Slow activity is a common feature of both sleep and anaesthesia. There is also evidence that some anaesthetics satisfy the homeostatic need for sleep (Pal2011). By using a within-subject design, we will explore the commonality of these mechanisms further by using EEG recordings of sleep prior to fMRI scanning. We will investigate the effect of tCS on the developed EEG consciousness metrics to elucidate whether the proposed brain interference methods will allow the required dose for anaesthesia-induced loss of consciousness to be reduced, thus reducing the known risks of over-anaesthesia.
Experimental results. Issue 3T3.2 Sleep (IFADO, UMI, STA): We will explore if lucid dreaming, which is a unique consciousness model in which primary consciousness – normally present during sleep – is transferred to the secondary mode of consciousness, is associated with specific FC alterations beyond regional prefrontal changes as demonstrated recently (Voss2014). We will systematically modulate connectivity to explore if these physiological processes are causally related to lucidity and to which degree specific FC patterns (frequency bands, synchrony) contribute. Oscillatory activity and connectivity will be studied with the advanced EEG models developed in WP1, and interventional stimulation will be performed. We will monitor sleep-dependent alterations of oscillatory activity with specific relation to FC alterations depending on relaxed wakefulness, drowsiness, light sleep, deep slow wave sleep, and REM-sleep in healthy subjects. The results will provide the basis for testing causality via tCS. We will explore consciousness modulation in healthy subjects as well as in patients suffering from sleep disturbance syndromes, i.e., psychophysiological insomnia states, and narcolepsy. The results of this study will elucidate how states of consciousness can be modulated by NIBS, and whether/how pathological alterations of state changes can be counteracted [IFADO]. PCI-based experiments will be conducted on healthy sleeping subjects in order to find the optimal stimulation parameters that are effective in reducing the magnitude and the rate of occurrence of spontaneously occurring and evoked (NIBS, somatosensory, visual, auditory) cortical downstates. It will also allow testing whether tCS, by reducing bistability, may affect the level of consciousness by promoting a sleep stage transition (e.g., from sleep stage N1 to wakefulness, from dreaming to lucid dreaming). [UMI]
Ethical Advisory Board Report. Issue 1Report of the external Ethical Advisory Board as requested by the Ethical check
Consciousness: models, metrics and intervention. Issue 2T1.1 Neuroscience, Consciousness & Bits (UMI, all): We will review models of consciousness, the relevance of information integration, KAC, bistability, brain rhythms related with consciousness and other explanatory correlates, and study implications for artificial systems and other cognitive sciences. Guide experimental work: specify methods for consciousness characterization, from classical spectral measures to information transfer, connectivity and complex network EEG metrics; explore intrinsic bistability of cortical neurons as a final common pathway leading to a decreased capacity for information integration (indexed by PCI and other metrics) during loss of consciousness; propose how to test hypotheses by studying the effects of different types of perturbations (NIBS, PNS) on EEG recorded during different consciousness conditions; explore the possibility of calculating PCI, or of detecting signs of cortical bistability, starting from stimulation protocols such as tCS and PNS-mediated stimulation (i.e., oddballs, local-global paradigm, subject’s own name); define KAC metrics: 1) using auditory stimuli and study associated functional networks; 2) explore the existence of similar signals using NIBS 3) evaluate tACS perturbation on EEG to create an analogue of sensory ERP. Design techniques to detect the occurrence of perturbation-induced cortical downstates, including period-amplitude analysis of evoked slow waves, time-frequency decomposition and empirical mode decomposition; assess the impact of the downstate on causality at each single recording site by calculating phase-locking factor (Lachaux1999), and the impact of the downstate on causality across recording sites by calculating the phase-locking value (Palva2010). Pre-select appropriate EEG feedback loops in NIBS and guide the EEG feature search (WP2). Finally, organise the 2-3 day yearly project workshops for brainstorming and experimental design. As a final task in the project the experimental results obtained in WP3 will be interpreted and transformed into theoretical advances on consciousness understanding.
T2.4 Experiment prototype integration and validation (STA, INSERM, IFADO): In the last project iteration we will integrate validated metrics with the developed close-loop techniques in a safe prototype for adaptive neuromodulation in consciousness studies and clinical applications. Visualization tools will be developed to monitor subject responses. This prototype for adaptive neuromodulation will be experimentally validated in a pilot (IFADO, all). Validation of the prototype and model predictions will be attained in the visual perception experiment. Parameters for tCS and close-loop tCS will be provided by the model and correlated with experimental results. Conclusions and requirements for the final device implementation will be delivered.
Project website and communication materialsAll communication materials including brochures, corporate identity, and web site.
Publications
Auteurs:
Min-Fang Kuo, Po-See Chen, Michael A. Nitsche
Publié dans:
International Review of Psychiatry, Numéro 29/2, 2017, Page(s) 146-167, ISSN 0954-0261
Éditeur:
Brunner - Routledge (US)
DOI:
10.1080/09540261.2017.1286299
Auteurs:
A. Antal, I. Alekseichuk, M. Bikson, J. Brockmöller, A.R. Brunoni, R. Chen, L.G. Cohen, G. Dowthwaite, J. Ellrich, A. Flöel, F. Fregni, M.S. George, R. Hamilton, J. Haueisen, C.S. Herrmann, F.C. Hummel, J.P. Lefaucheur, D. Liebetanz, C.K. Loo, C.D. McCaig, C. Miniussi, P.C. Miranda, V. Moliadze, M.A. Nitsche, R. Nowak, F. Padberg, A. Pascual-Leone, W. Poppendieck, A. Priori, S. Rossi, P.M. Rossi
Publié dans:
Clinical Neurophysiology, Numéro 128/9, 2017, Page(s) 1774-1809, ISSN 1388-2457
Éditeur:
Elsevier BV
DOI:
10.1016/j.clinph.2017.06.001
Auteurs:
Rafael Polanía, Michael A. Nitsche, Christian C. Ruff
Publié dans:
Nature Neuroscience, Numéro 21/2, 2018, Page(s) 174-187, ISSN 1097-6256
Éditeur:
Nature Publishing Group
DOI:
10.1038/s41593-017-0054-4
Auteurs:
Asif Jamil, Michael A. Nitsche
Publié dans:
Current Behavioral Neuroscience Reports, Numéro 4/4, 2017, Page(s) 331-340, ISSN 2196-2979
Éditeur:
Springer International Publishing
DOI:
10.1007/s40473-017-0134-5
Auteurs:
Andrés Molero-Chamizo, José R. Alameda Bailén, Tamara Garrido Béjar, Macarena García López, Inmaculada Jaén Rodríguez, Carolina Gutiérrez Lérida, Silvia Pérez Panal, Gloria González Ángel, Laura Lemus Corchero, María J. Ruiz Vega, Michael A. Nitsche, Guadalupe N. Rivera-Urbina
Publié dans:
Cognitive, Affective, & Behavioral Neuroscience, Numéro 18/1, 2018, Page(s) 167-175, ISSN 1530-7026
Éditeur:
Psychonomic Society Inc.
DOI:
10.3758/s13415-018-0561-0
Auteurs:
Fatemeh Yavari, Asif Jamil, Mohsen Mosayebi Samani, Liliane Pinto Vidor, Michael A. Nitsche
Publié dans:
Neuroscience & Biobehavioral Reviews, Numéro 85, 2018, Page(s) 81-92, ISSN 0149-7634
Éditeur:
Pergamon Press Ltd.
DOI:
10.1016/j.neubiorev.2017.06.015
Auteurs:
Silvia Casarotto, Angela Comanducci, Mario Rosanova, Simone Sarasso, Matteo Fecchio, Martino Napolitani, Andrea Pigorini, Adenauer G. Casali, Pietro D. Trimarchi, Melanie Boly, Olivia Gosseries, Olivier Bodart, Francesco Curto, Cristina Landi, Maurizio Mariotti, Guya Devalle, Steven Laureys, Giulio Tononi, Marcello Massimini
Publié dans:
Annals of Neurology, 2016, ISSN 1531-8249
Éditeur:
John Wiley & Sons
DOI:
10.1002/ana.24779
Auteurs:
Christof Koch, Marcello Massimini, Melanie Boly, Giulio Tononi
Publié dans:
Nature Reviews Neuroscience, Numéro 17/5, 2016, Page(s) 307-321, ISSN 1471-003X
Éditeur:
Nature Publishing Group
DOI:
10.1038/nrn.2016.22
Auteurs:
Jaakko O. Nieminen, Olivia Gosseries, Marcello Massimini, Elyana Saad, Andrew D. Sheldon, Melanie Boly, Francesca Siclari, Bradley R. Postle, Giulio Tononi
Publié dans:
Scientific Reports, 2016, ISSN 2045-2322
Éditeur:
Nature Publishing Group
DOI:
10.1038/srep30932
Auteurs:
Olivier Bodart, Olivia Gosseries, Sarah Wannez, Aurore Thibaut, Jitka Annen, Melanie Boly, Mario Rosanova, Adenauer G. Casali, Silvia Casarotto, Giulio Tononi, Marcello Massimini, Steven Laureys
Publié dans:
Neuroimage: Clinical, 2017, ISSN 2213-1582
Éditeur:
Elsevier BV
DOI:
10.1016/j.nicl.2017.02.002
Auteurs:
Ujwal Chaudhary, Niels Birbaumer, Ander Ramos-Murguialday
Publié dans:
Nature Reviews Neurology, Numéro 12/9, 2016, Page(s) 513-525, ISSN 1759-4758
Éditeur:
Nature Publishing Group
DOI:
10.1038/nrneurol.2016.113
Auteurs:
Ranganatha Sitaram, Tomas Ros, Luke Stoeckel, Sven Haller, Frank Scharnowski, Jarrod Lewis-Peacock, Nikolaus Weiskopf, Maria Laura Blefari, Mohit Rana, Ethan Oblak, Niels Birbaumer, James Sulzer
Publié dans:
Nature Reviews Neuroscience, Numéro 18/2, 2016, Page(s) 86-100, ISSN 1471-003X
Éditeur:
Nature Publishing Group
DOI:
10.1038/nrn.2016.164
Auteurs:
Ujwal Chaudhary, Bin Xia, Stefano Silvoni, Leonardo G. Cohen, Niels Birbaumer
Publié dans:
PLOS Biology, 2017, ISSN 1544-9173
Éditeur:
Public Library of Science
DOI:
10.1371/journal.pbio.1002593
Auteurs:
Wangshan Huang, Sarah Wannez, Felipe Fregni, Xiaohua Hu, Shan Jing, Geraldine Martens, Minhui He, Haibo Di, Steven Laureys, Aurore Thibaut
Publié dans:
Brain Stimulation, Numéro 10/3, 2017, Page(s) 718-720, ISSN 1935-861X
Éditeur:
Elsevier BV
DOI:
10.1016/j.brs.2017.02.001
Auteurs:
Enrico Amico, Olivier Bodart, Mario Rosanova, Olivia Gosseries, Lizette Heine, Pieter Van Mierlo, Charlotte Martial, Marcello Massimini, Daniele Marinazzo, Steven Laureys
Publié dans:
Brain Connectivity, Numéro 7/2, 2017, Page(s) 84-97, ISSN 2158-0014
Éditeur:
Mary Ann Liebert Inc.
DOI:
10.1089/brain.2016.0462
Auteurs:
Lukas Frase, Hannah Piosczyk, Sulamith Zittel, Friederike Jahn, Peter Selhausen, Lukas Krone, Bernd Feige, Florian Mainberger, Jonathan G Maier, Marion Kuhn, Stefan Klöppel, Claus Normann, Annette Sterr, Kai Spiegelhalder, Dieter Riemann, Michael A Nitsche, Christoph Nissen
Publié dans:
Neuropsychopharmacology, Numéro 41/10, 2016, Page(s) 2577-2586, ISSN 0893-133X
Éditeur:
Nature Publishing Group
DOI:
10.1038/npp.2016.65
Auteurs:
Fatemeh Yavari, Michael Nitsche and Hamed Ekhtiari
Publié dans:
Frontiers in Human Neuroscience, Numéro 11:159, 2017, ISSN 1662-5161
Éditeur:
Frontiers Research Foundation
DOI:
10.3389/fnhum.2017.00159
Auteurs:
Géraldine Martens, Felipe Fregni, Manon Carrière, Alice Barra, Steven Laureys, Aurore Thibaut
Publié dans:
Brain Injury, Numéro 33/13-14, 2019, Page(s) 1679-1683, ISSN 0269-9052
Éditeur:
Taylor & Francis
DOI:
10.1080/02699052.2019.1667537
Auteurs:
Wannez, Sarah; Heine, Lizette; Thonnard, Marie; Gosseries, Olivia; Laureys, Steven; Coma Science Group Collaborators
Publié dans:
Annals of Neurology, Numéro 2, 2017, ISSN 1531-8249
Éditeur:
Wiley Online Library
DOI:
10.5281/zenodo.1194509
Auteurs:
R.D. Sanders, M.I. Banks, M. Darracq, R. Moran, J. Sleigh, O. Gosseries, V. Bonhomme, J.F. Brichant, M. Rosanova, A. Raz, G. Tononi, M. Massimini, S. Laureys, M. Boly
Publié dans:
British Journal of Anaesthesia, Numéro 121/5, 2018, Page(s) 1084-1096, ISSN 0007-0912
Éditeur:
Oxford University Press
DOI:
10.1016/j.bja.2018.07.006
Auteurs:
Tim Bayne, Anil K. Seth, Marcello Massimini
Publié dans:
Trends in Neurosciences, Numéro 43/1, 2020, Page(s) 6-16, ISSN 0166-2236
Éditeur:
Elsevier BV
DOI:
10.1016/j.tins.2019.11.003
Auteurs:
A. Kabbara, W. EL Falou, M. Khalil, F. Wendling, M. Hassan
Publié dans:
Scientific Reports, Numéro 7/1, 2017, ISSN 2045-2322
Éditeur:
Nature Publishing Group
DOI:
10.1038/s41598-017-03420-6
Auteurs:
Matteo Fecchio, Andrea Pigorini, Angela Comanducci, Simone Sarasso, Silvia Casarotto, Isabella Premoli, Chiara-Camilla Derchi, Alice Mazza, Simone Russo, Federico Resta, Fabio Ferrarelli, Maurizio Mariotti, Ulf Ziemann, Marcello Massimini, Mario Rosanova
Publié dans:
PLOS ONE, Numéro 12/9, 2017, Page(s) e0184910, ISSN 1932-6203
Éditeur:
Public Library of Science
DOI:
10.1371/journal.pone.0184910
Auteurs:
Michele Angelo Colombo, Martino Napolitani, Melanie Boly, Olivia Gosseries, Silvia Casarotto, Mario Rosanova, Jean-Francois Brichant, Pierre Boveroux, Steffen Rex, Steven Laureys, Marcello Massimini, Arturo Chieregato, Simone Sarasso
Publié dans:
NeuroImage, Numéro 189, 2019, Page(s) 631-644, ISSN 1053-8119
Éditeur:
Academic Press
DOI:
10.1016/j.neuroimage.2019.01.024
Auteurs:
M. Rosanova, M. Fecchio, S. Casarotto, S. Sarasso, A. G. Casali, A. Pigorini, A. Comanducci, F. Seregni, G. Devalle, G. Citerio, O. Bodart, M. Boly, O. Gosseries, S. Laureys, M. Massimini
Publié dans:
Nature Communications, Numéro 9/1, 2018, ISSN 2041-1723
Éditeur:
Nature Publishing Group
DOI:
10.1038/s41467-018-06871-1
Auteurs:
Wannez, Sarah; Gosseries, Olivia; Azzolini, Deborah; Martial, Charlotte; Cassol, Helena; Aubinet, Charlène; Annen, Jitka; Martens, Géraldine; Bodart, Olivier; Heine, Lizette; Charland-Verville, Vanessa; Thibaut, Aurore; Chatelle, Camille; Vanhaudenhuyse, Audrey; Demertzi, Athena; Schnakers, Caroline; Donneau, Anne-Françoise; Laureys, Steven
Publié dans:
Neuropsychological Rehabilitation, Numéro 5, 2018, ISSN 0960-2011
Éditeur:
Psychology Press
DOI:
10.5281/zenodo.1194504
Auteurs:
Chennu, Shrivas; Annen, Jitka; Wannez, Sarah; Chatelle, Camille; Cassol, Helena; Martens, Géraldine; Schnakers, Caroline; Gosseries, Olivia; Menon, David; Laureys, Steven
Publié dans:
Brain, Numéro 6, 2017, ISSN 0006-8950
Éditeur:
Oxford University Press
DOI:
10.5281/zenodo.1194511
Auteurs:
Giulio Ruffini
Publié dans:
Neuroscience of Consciousness, Numéro 2017/1, 2017, ISSN 2057-2107
Éditeur:
Oxford: Oxford University Press
DOI:
10.1093/nc/nix019
Auteurs:
Julien Modolo, Mahmoud Hassan, Fabrice Wendling, Pascal Benquet
Publié dans:
Network Neuroscience, Numéro 4/2, 2020, Page(s) 315-337, ISSN 2472-1751
Éditeur:
MIT Press
DOI:
10.1162/netn_a_00119
Auteurs:
Siouar Bensaid, Julien Modolo, Isabelle Merlet, Fabrice Wendling, Pascal Benquet
Publié dans:
Frontiers in Systems Neuroscience, Numéro 13, 2019, ISSN 1662-5137
Éditeur:
Frontiers Research Foundation
DOI:
10.3389/fnsys.2019.00059
Auteurs:
Renzo Comolatti, Andrea Pigorini, Silvia Casarotto, Matteo Fecchio, Guilherme Faria, Simone Sarasso, Mario Rosanova, Olivia Gosseries, Mélanie Boly, Olivier Bodart, Didier Ledoux, Jean-François Brichant, Lino Nobili, Steven Laureys, Giulio Tononi, Marcello Massimini, Adenauer G. Casali
Publié dans:
Brain Stimulation, Numéro 12/5, 2019, Page(s) 1280-1289, ISSN 1935-861X
Éditeur:
Elsevier BV
DOI:
10.1016/j.brs.2019.05.013
Auteurs:
Aurore Thibaut, Sarah Wannez, Anne-Francoise Donneau, Camille Chatelle, Olivia Gosseries, Marie-Aurélie Bruno, Steven Laureys
Publié dans:
Brain Injury, Numéro 31/4, 2017, Page(s) 466-474, ISSN 0269-9052
Éditeur:
Taylor & Francis
DOI:
10.1080/02699052.2016.1274776
Auteurs:
Zulay Lugo, Fréderic Pellas, Veronique Blandin, Steven Laureys, Olivia Gosseries
Publié dans:
Brain Injury, Numéro 31/12, 2017, Page(s) 1590-1596, ISSN 0269-9052
Éditeur:
Taylor & Francis
DOI:
10.1080/02699052.2017.1347277
Auteurs:
Warnaby, Catherine E.; Sleigh, Jamie W.; Hight, Darren; Jbabdi, Saad; Tracey, Irene
Publié dans:
Anesthesiology 127(4) 645-657, Numéro 12, 2017, ISSN 0003-3022
Éditeur:
Lippincott Williams & Wilkins Ltd.
DOI:
10.5281/zenodo.1182660
Auteurs:
Olivier Bodart, Enrico Amico, Francisco Gómez, Adenauer G. Casali, Sarah Wannez, Lizette Heine, Aurore Thibaut, Jitka Annen, Melanie Boly, Silvia Casarotto, Mario Rosanova, Marcello Massimini, Steven Laureys, Olivia Gosseries
Publié dans:
Brain Stimulation, Numéro 11/2, 2018, Page(s) 358-365, ISSN 1935-861X
Éditeur:
Elsevier BV
DOI:
10.1016/j.brs.2017.11.006
Auteurs:
Aurore Thibaut, Camille Chatelle, Audrey Vanhaudenhuyse, Géraldine Martens, Helena Cassol, Charlotte Martial, Manon Carrière, Alice Barra, Steven Laureys, Olivia Gosseries
Publié dans:
Brain Stimulation, Numéro 11/3, 2018, Page(s) 642-644, ISSN 1935-861X
Éditeur:
Elsevier BV
DOI:
10.1016/j.brs.2018.02.002
Auteurs:
Carlo Cavaliere, Marco Aiello, Carol Di Perri, Enrico Amico, Charlotte Martial, Aurore Thibaut, Steven Laureys, Andrea Soddu
Publié dans:
Frontiers in Cellular Neuroscience, Numéro 10, 2016, ISSN 1662-5102
Éditeur:
Frontiers Research Foundation
DOI:
10.3389/fncel.2016.00257
Auteurs:
Jamie Sleigh, Rebecca M. Pullon, Phillip E. Vlisides, Catherine E. Warnaby
Publié dans:
British Journal of Anaesthesia, Numéro 123/5, 2019, Page(s) 592-600, ISSN 0007-0912
Éditeur:
Oxford University Press
DOI:
10.1016/j.bja.2019.07.021
Auteurs:
Julien Modolo, Mahmoud Hassan, Giulio Ruffini, Alexandre Legros
Publié dans:
Journal of Neural Engineering, 2019, ISSN 1741-2560
Éditeur:
Institute of Physics Publishing
DOI:
10.1088/1741-2552/ab97f7
Auteurs:
J. Sleigh, C. Warnaby, I. Tracey
Publié dans:
British Journal of Anaesthesia, Numéro 121/1, 2018, Page(s) 233-240, ISSN 0007-0912
Éditeur:
Oxford University Press
DOI:
10.1016/j.bja.2017.12.038
Auteurs:
Majid Khalili Ardali, Aygul Rana, Mehdi Purmohammad, Niels Birbaumer, Ujwal Chaudhary
Publié dans:
Brain and Language, Numéro 194, 2019, Page(s) 93-97, ISSN 0093-934X
Éditeur:
Academic Press
DOI:
10.1016/j.bandl.2019.05.004
Auteurs:
Azim Malekshahi, Ujwal Chaudhary, Andres Jaramillo-Gonzalez, Alberto Lucas Luna, Aygul Rana, Alessandro Tonin, Niels Birbaumer, Steffen Gais
Publié dans:
Sleep, Numéro 42/12, 2019, ISSN 0161-8105
Éditeur:
The American Academy of Sleep Medicine
DOI:
10.1093/sleep/zsz185
Auteurs:
Yasuhisa Maruyama, Natsue Yoshimura, Aygul Rana, Azim Malekshahi, Alessandro Tonin, Andres Jaramillo-Gonzalez, Niels Birbaumer, Ujwal Chaudhary
Publié dans:
Neuroscience Research, 2020, ISSN 0168-0102
Éditeur:
Elsevier BV
DOI:
10.1016/j.neures.2020.01.013
Auteurs:
Ujwal Chaudhary, Natalie Mrachacz‐Kersting, Niels Birbaumer
Publié dans:
The Journal of Physiology, 2020, ISSN 0022-3751
Éditeur:
Blackwell Publishing Inc.
DOI:
10.1113/jp278775
Auteurs:
Jayro Martínez-Cerveró, Majid Khalili Ardali, Andres Jaramillo-Gonzalez, Shizhe Wu, Alessandro Tonin, Niels Birbaumer, Ujwal Chaudhary
Publié dans:
Sensors, Numéro 20/9, 2020, Page(s) 2443, ISSN 1424-8220
Éditeur:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/s20092443
Auteurs:
Alessandro Tonin, Andres Jaramillo-Gonzalez, Aygul Rana, Majid Khalili-Ardali, Niels Birbaumer, Ujwal Chaudhary
Publié dans:
Scientific Reports, Numéro 10/1, 2020, ISSN 2045-2322
Éditeur:
Nature Publishing Group
DOI:
10.1038/s41598-020-65333-1
Auteurs:
Katrin Sippel, Julia Moser, Franziska Schleger, Hubert Preissl, Wolfgang Rosenstiel, Martin Spüler
Publié dans:
Computer Methods and Programs in Biomedicine, Numéro 173, 2019, Page(s) 35-41, ISSN 0169-2607
Éditeur:
Elsevier BV
DOI:
10.1016/j.cmpb.2019.02.016
Auteurs:
Julia Moser, Siouar Bensaid, Eleni Kroupi, Franziska Schleger, Fabrice Wendling, Giulio Ruffini, Hubert Preißl
Publié dans:
Frontiers in Systems Neuroscience, Numéro 13, 2019, ISSN 1662-5137
Éditeur:
Frontiers Research Foundation
DOI:
10.3389/fnsys.2019.00023
Auteurs:
Alessandro Tonin, Niels Birbaumer, Ujwal Chaudhary
Publié dans:
Brain Sciences, Numéro 8/7, 2018, Page(s) 126, ISSN 2076-3425
Éditeur:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/brainsci8070126
Auteurs:
Charlène Aubinet, Lesley Murphy, Mohamed A. Bahri, Stephen K. Larroque, Helena Cassol, Jitka Annen, Manon Carrière, Sarah Wannez, Aurore Thibaut, Steven Laureys, Olivia Gosseries
Publié dans:
Frontiers in Neurology, Numéro 9, 2018, ISSN 1664-2295
Éditeur:
Frontiers Research Foundation
DOI:
10.3389/fneur.2018.00665
Auteurs:
Jennifer Rizkallah, Jitka Annen, Julien Modolo, Olivia Gosseries, Pascal Benquet, Sepehr Mortaheb, Hassan Amoud, Helena Cassol, Ahmad Mheich, Aurore Thibaut, Camille Chatelle, Mahmoud Hassan, Rajanikant Panda, Fabrice Wendling, Steven Laureys
Publié dans:
NeuroImage: Clinical, Numéro 23, 2019, Page(s) 101841, ISSN 2213-1582
Éditeur:
Elsevier BV
DOI:
10.1016/j.nicl.2019.101841
Auteurs:
A. Demertzi, E. Tagliazucchi, S. Dehaene, G. Deco, P. Barttfeld, F. Raimondo, C. Martial, D. Fernández-Espejo, B. Rohaut, H. U. Voss, N. D. Schiff, A. M. Owen, S. Laureys, L. Naccache, J. D. Sitt
Publié dans:
Science Advances, Numéro 5/2, 2019, Page(s) eaat7603, ISSN 2375-2548
Éditeur:
AAAS
DOI:
10.1126/sciadv.aat7603
Auteurs:
Jennifer Rizkallah, Hassan Amoud, Matteo Fraschini, Fabrice Wendling, Mahmoud Hassan
Publié dans:
Brain Topography, Numéro 33/2, 2020, Page(s) 151-160, ISSN 0896-0267
Éditeur:
Kluwer Academic/Plenum Publishers
DOI:
10.1007/s10548-020-00753-w
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