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Brain injury and trauma monitoring using advanced photonics

Resultado final

Supervisory Board meeting

compulsory deliverable

ETHICS, delivery of documents

compulsory deliverable

Mid term review meeting

compulsory deliverable

Draft period Report

compulsory deliverable

Project website, committees, printed materials

Project and network organisation and promotion

Progress report

compulsory deliverable

Report a standard data format for DCS & TRS

Develop and utilise a standard format for all systems

Integrate DCS in NIRFAST

Addition and testing of DCS toolbox in NIRFAST

Publicaciones

Correction of an adding-doubling inversion algorithm for the measurement of the optical parameters of turbid media

Autores: Paul Lemaillet, Catherine C. Cooksey, Jeeseong Hwang, Heidrun Wabnitz, Dirk Grosenick, Lin Yang, David W. Allen
Publicado en: Biomedical Optics Express, Edición 9/1, 2018, Página(s) 55, ISSN 2156-7085
Editor: The Optical Society
DOI: 10.1364/BOE.9.000055

Hyperspectral imaging solutions for brain tissue metabolic and hemodynamic monitoring: past, current and future developments

Autores: Luca Giannoni, Frédéric Lange, Ilias Tachtsidis
Publicado en: Journal of Optics, Edición 20/4, 2018, Página(s) 044009, ISSN 2040-8978
Editor: Institute of Physics Publishing
DOI: 10.1088/2040-8986/aab3a6

Cerebral Hemodynamic Influences in Task-Related Functional Magnetic Resonance Imaging and Near-Infrared Spectroscopy in Acute Sport-Related Concussion: A Review

Autores: Mario Forcione, Claudio Colonnese, Antonio Belli
Publicado en: Journal of Imaging, Edición 4/4, 2018, Página(s) 59, ISSN 2313-433X
Editor: MDPI
DOI: 10.3390/jimaging4040059

Time-Domain Functional Diffuse Optical Tomography System Based on Fiber-Free Silicon Photomultipliers

Autores: Andrea Farina, Susanna Tagliabue, Laura Di Sieno, Edoardo Martinenghi, Turgut Durduran, Simon Arridge, Fabrizio Martelli, Alessandro Torricelli, Antonio Pifferi, Alberto Dalla Mora
Publicado en: Applied Sciences, Edición 7/12, 2017, Página(s) 1235, ISSN 2076-3417
Editor: MDPI
DOI: 10.3390/app7121235

L 1 -norm based nonlinear reconstruction improves quantitative accuracy of spectral diffuse optical tomography

Autores: Wenqi Lu, Daniel Lighter, Iain B. Styles
Publicado en: Biomedical Optics Express, Edición 9/4, 2018, Página(s) 1423, ISSN 2156-7085
Editor: The Optical Society
DOI: 10.1364/BOE.9.001423

Salivary MicroRNAs: Diagnostic Markers of Mild Traumatic Brain Injury in Contact-Sport

Autores: Valentina Di Pietro, Edoardo Porto, Marco Ragusa, Cristina Barbagallo, David Davies, Mario Forcione, Ann Logan, Cinzia Di Pietro, Michele Purrello, Michael Grey, Douglas Hammond, Vijay Sawlani, Aron K. Barbey, Antonio Belli
Publicado en: Frontiers in Molecular Neuroscience, Edición 11, 2018, ISSN 1662-5099
Editor: Frontiers Research Foundation
DOI: 10.3389/fnmol.2018.00290

Early microvascular cerebral blood flow response to head-of-bed elevation is related to outcome in acute ischemic stroke

Autores: Clara Gregori-Pla, Igor Blanco, Pol Camps-Renom, Peyman Zirak, Isabel Serra, Gianluca Cotta, Federica Maruccia, Luís Prats-Sánchez, Alejandro Martínez-Domeño, David R. Busch, Giacomo Giacalone, Joan Martí-Fàbregas, Turgut Durduran, Raquel Delgado-Mederos
Publicado en: Journal of Neurology, 2019, ISSN 0340-5354
Editor: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00415-019-09226-y

New nonlocal forward model for diffuse optical tomography

Autores: Wenqi Lu, Jinming Duan, Joshua Deepak Veesa, Iain B Styles
Publicado en: Biomedical Optics Express, Edición 10/12, 2019, Página(s) 6227, ISSN 2156-7085
Editor: The Optical Society
DOI: 10.1364/boe.10.006227

Hyper-spectral Recovery of Cerebral and Extra-Cerebral Tissue Properties Using Continuous Wave Near-Infrared Spectroscopic Data

Autores: Joshua Deepak Veesa, Hamid Dehghani
Publicado en: Applied Sciences, Edición 9/14, 2019, Página(s) 2836, ISSN 2076-3417
Editor: MDPI open access journals
DOI: 10.3390/app9142836

Spatially-enhanced time-domain NIRS for accurate determination of tissue optical properties

Autores: Lin Yang, Heidrun Wabnitz, Thomas Gladytz, Rainer Macdonald, Dirk Grosenick
Publicado en: Optics Express, Edición 27/19, 2019, Página(s) 26415, ISSN 1094-4087
Editor: Optical Society of America
DOI: 10.1364/oe.27.026415

Graph- and finite element-based total variation models for the inverse problem in diffuse optical tomography

Autores: Wenqi Lu, Jinming Duan, David Orive-Miguel, Lionel Herve, Iain B. Styles
Publicado en: Biomedical Optics Express, Edición 10/6, 2019, Página(s) 2684, ISSN 2156-7085
Editor: The Optical Society
DOI: 10.1364/boe.10.002684

Functional near infrared spectroscopy using spatially resolved data to account for tissue scattering: A numerical study and arm‐cuff experiment

Autores: Joshua D. Veesa, Hamid Dehghani
Publicado en: Journal of Biophotonics, Edición 12/10, 2019, ISSN 1864-063X
Editor: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/jbio.201900064

Eight-Wavelength, Dual Detection Channel Instrument for Near-Infrared Time-Resolved Diffuse Optical Spectroscopy

Autores: Marco Renna, Mauro Buttafava, Anurag Behera, Marta Zanoletti, Laura Di Sieno, Alberto Dalla Mora, Davide Contini, Alberto Tosi
Publicado en: IEEE Journal of Selected Topics in Quantum Electronics, Edición 25/1, 2019, Página(s) 1-11, ISSN 1077-260X
Editor: Institute of Electrical and Electronics Engineers
DOI: 10.1109/jstqe.2018.2863570

Self-calibrating time-resolved near infrared spectroscopy

Autores: Stanislaw Wojtkiewicz, Anna Gerega, Marta Zanoletti, Aleh Sudakou, Davide Contini, Adam Liebert, Turgut Durduran, Hamid Dehghani
Publicado en: Biomedical Optics Express, Edición 10/5, 2019, Página(s) 2657, ISSN 2156-7085
Editor: The Optical Society
DOI: 10.1364/boe.10.002657

Depth-resolved assessment of changes in concentration of chromophores using time-resolved near-infrared spectroscopy: estimation of cytochrome-c-oxidase uncertainty by Monte Carlo simulations

Autores: Aleh Sudakou, Stanislaw Wojtkiewicz, Frédéric Lange, Anna Gerega, Piotr Sawosz, Ilias Tachtsidis, Adam Liebert
Publicado en: Biomedical Optics Express, Edición 10/9, 2019, Página(s) 4621, ISSN 2156-7085
Editor: The Optical Society
DOI: 10.1364/boe.10.004621

Frequency-domain vs continuous-wave near-infrared spectroscopy devices: a comparison of clinically viable monitors in controlled hypoxia

Autores: David James Davies, Michael Clancy, Daniel Lighter, George M. Balanos, Samuel John Edwin Lucas, Hamid Dehghani, Zhangjie Su, Mario Forcione, Antonio Belli
Publicado en: Journal of Clinical Monitoring and Computing, Edición 31/5, 2017, Página(s) 967-974, ISSN 1387-1307
Editor: Kluwer Academic Publishers
DOI: 10.1007/s10877-016-9942-5

Polydimethylsiloxane tissue-mimicking phantoms for quantitative optical medical imaging standards

Autores: Jeeseong Hwang, Hyun-Jin Kim, Paul Lemaillet, Heidrun Wabnitz, Dirk Grosenick, Lin Yang, Thomas Gladytz, David McClatchy, David Allen, Kimberly Briggman, Brian Pogue
Publicado en: Design and Quality for Biomedical Technologies X, 2017, Página(s) 1005603
Editor: SPIE
DOI: 10.1117/12.2263379

Broadband spectral measurements of diffuse optical properties by an integrating sphere instrument at the National Institute of Standards and Technology

Autores: Paul Lemaillet, Jeeseong Hwang, Heidrun Wabnitz, Dirk Grosenick, Lin Yang, David W. Allen
Publicado en: Design and Quality for Biomedical Technologies X, 2017, Página(s) 1005604
Editor: SPIE
DOI: 10.1117/12.2263338

In vivo depth heterogeneity of the abdomen assessed by broadband time-domain diffuse optical spectroscopy

Autores: Sanathana Konugolu, Claudia Guadagno, Lorenzo Spinelli, Pranav Lanka, Paola Taroni, Rinaldo Cubeddu, Enzo Nisoli, Antonio Pifferi, Andrea Farina
Publicado en: Diffuse Optical Spectroscopy and Imaging VI, 2017, Página(s) 39, ISBN 9781-510612839
Editor: SPIE
DOI: 10.1117/12.2286067

Spectrally constrained L1-norm improves quantitative accuracy of diffuse optical tomography

Autores: Wenqi Lu, Iain B. Styles
Publicado en: Diffuse Optical Spectroscopy and Imaging VI, 2017, Página(s) 1041211
Editor: SPIE
DOI: 10.1117/12.2285996

An innovative 8 channels system for time-resolved diffuse optical tomography based on SiPMs

Autores: E. Martinenghi, L. Di Sieno, S. Tagliabue, A. Dalla Mora, A. Farina, A. Pifferi
Publicado en: 2016 IEEE Photonics Conference (IPC), 2016, Página(s) 1-2, ISBN 978-1-5090-1906-9
Editor: IEEE
DOI: 10.1109/IPCon.2016.7831149

Spatially-enhanced Data Analysis Method for Time-resolved NIRS to Determine Tissue Optical Properties

Autores: Lin Yang, Heidrun Wabnitz, Dirk Grosenick, Thomas Gladytz, Rainer Macdonald
Publicado en: Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS), 2018, Página(s) JW3A.31, ISBN 978-1-943580-41-5
Editor: OSA
DOI: 10.1364/TRANSLATIONAL.2018.JW3A.31

Study of optimal measurement conditions for time-domain diffuse optics systems

Autores: Anurag Behera, Laura Di Sieno, Antonio Pifferi, Fabrizio Martelli, Alberto Dalla Mora
Publicado en: Biophotonics: Photonic Solutions for Better Health Care VI, 2018, Página(s) 40, ISBN 9781-510618978
Editor: SPIE
DOI: 10.1117/12.2307370

Time-resolved Diffuse Correlation Spectroscopy based on Commercial Laser Module

Autores: Saeed Samaei, Piotr Sawosz, Anna Gerega, Adam Liebert
Publicado en: Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS), 2018, Página(s) OTu2D.3, ISBN 978-1-943580-41-5
Editor: OSA
DOI: 10.1364/OTS.2018.OTu2D.3

Spectrally Constrained Approach of Spatially Resolved Spectroscopy: Towards a Better Estimate of Tissue Oxygenation

Autores: JOSHUA DEEPAK VEESA, Hamid Dehghani
Publicado en: Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS), 2018, Página(s) JTh3A.37, ISBN 978-1-943580-41-5
Editor: OSA
DOI: 10.1364/TRANSLATIONAL.2018.JTh3A.37

Nonlocal Differential Operators Improve Image Reconstruction in Diffuse Optical Tomography

Autores: Wenqi Lu, Iain Styles
Publicado en: Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS), 2018, Página(s) JTu3A.32, ISBN 978-1-943580-41-5
Editor: OSA
DOI: 10.1364/TRANSLATIONAL.2018.JTu3A.32

Microvascular Cerebral Blood Flow Fluctuations Due to Periodic Apneas in Acute Ischemic Stroke

Autores: Clara Gregori Pla, Stella Avtzi, Gianluca Cotta, Giacomo Giacalone, Federica Maruccia, Pol Camps-Renom, Joan Martí-Fàbregas, Raquel Delgado-Mederos, Mercedes Mayos, Turgut Durduran
Publicado en: Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS), 2018, Página(s) CW2B.6, ISBN 978-1-943580-41-5
Editor: OSA
DOI: 10.1364/translational.2018.cw2b.6

Computational Performance of Time-Resolved Diffuse Optical Tomography in a Two-Layer Brain Model

Autores: David Orive Miguel, Lionel HERVE, Jérôme MARS, Laurent CONDAT, Jean-Marc DINTEN, Sophie Morales
Publicado en: Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS), 2018, Página(s) JTh3A.45, ISBN 978-1-943580-41-5
Editor: OSA
DOI: 10.1364/translational.2018.jth3a.45

The Impact of Hyperventilation Therapy on Cerebral Blood Flow and Oxygenation in Traumatic Brain Injured Patients Measured by Diffuse Optics

Autores: Susanna Tagliabue, Michal Kacprzak, Federica Maruccia, Julia Scheel, Lidia Castro, Marylin Riveiro Vilaboa, Anna Rey-Perez, María Antonia Poca, Juan Sahuquillo, Turgut Durduran
Publicado en: Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS), 2018, Página(s) CW2B.4, ISBN 978-1-943580-41-5
Editor: OSA
DOI: 10.1364/translational.2018.cw2b.4

A new forward model for diffuse optical tomography

Autores: Wenqi Lu, Jinming Duan, Joshua Deepak Veesa, Iain B. Styles
Publicado en: Diffuse Optical Spectroscopy and Imaging VII, 2019, Página(s) 83, ISBN 9781-510628427
Editor: SPIE
DOI: 10.1117/12.2527033

Noise reduction and compression of Monte-Carlo lookup tables by singular value decomposition (Conference Presentation)

Autores: Thomas Gladytz, Heidrun Wabnitz, Lin Yang, Dirk Grosenick
Publicado en: Design and Quality for Biomedical Technologies XII, 2019, Página(s) 4, ISBN 9781-510623835
Editor: SPIE
DOI: 10.1117/12.2506035

Digital phantom for time-domain near-infrared spectroscopy of tissue: concept and proof-of-principle experiments

Autores: Heidrun Wabnitz, Jeeseong Hwang, Lin Yang, Rainer Macdonald
Publicado en: Design and Quality for Biomedical Technologies XII, 2019, Página(s) 20, ISBN 9781-510623835
Editor: SPIE
DOI: 10.1117/12.2510405

Spectral parameter recovery of cerebral and extra-cerebral tissues using broadband near-infrared spectroscopy

Autores: Joshua Deepak Veesa, Hamid Dehghani
Publicado en: Diffuse Optical Spectroscopy and Imaging VII, 2019, Página(s) 84, ISBN 9781-510628427
Editor: SPIE
DOI: 10.1117/12.2526977

Multi-wavelength time-resolved NIRS measurements for estimation of absolute concentration of chromophores: blood phantom study

Autores: Aleh Sudakou, Frédéric Lange, Helene Isler, Anna Gerega, Daniel Ostojic, Piotr Sawosz, Ilias Tachtsidis, Martin Wolf, Adam Liebert
Publicado en: Diffuse Optical Spectroscopy and Imaging VII, 2019, Página(s) 72, ISBN 9781-510628427
Editor: SPIE
DOI: 10.1117/12.2527215

Spatially-enhanced time-domain NIRS for determination of optical properties in layered structures

Autores: Lin Yang, Pranav Lanka, Heidrun Wabnitz, Rinaldo Cubeddu, Thomas Gladytz, Sanathana Konugolu Venkata Sekar, Dirk Grosenick, Antonio Pifferi, Rainer Macdonald
Publicado en: Diffuse Optical Spectroscopy and Imaging VII, 2019, Página(s) 9, ISBN 9781-510628427
Editor: SPIE
DOI: 10.1117/12.2527032

Large area SiPM and high throughput timing electronics: toward new generation time-domain instruments

Autores: Anurag Behera, Laura Di Sieno, Sumeet Rohilla, Antonio Pifferi, Alessandro Torricelli, Davide Contini, Benedikt Kraemer, Felix Koberling, Alberto Dalla Mora
Publicado en: Diffuse Optical Spectroscopy and Imaging VII, 2019, Página(s) 1, ISBN 9781-510628427
Editor: SPIE
DOI: 10.1117/12.2526792

Multi-target immunofluorescence using spectral FLIM-FRET for separation of undesirable antibody cross-labeling

Autores: Sumeet Rohilla, Benedikt Kraemer, Felix Koberling, Ingo Gregor, Andreas C. Hocke
Publicado en: Advances in Microscopic Imaging II, 2019, Página(s) 45, ISBN 9781-510628465
Editor: SPIE
DOI: 10.1117/12.2526240

Time-domain diffuse correlation spectroscopy quantifies path-length-resolved dynamical properties of a layered turbid media

Autores: Saeed Samaei, Dawid Borycki, Michal Kacprzak, Piotr Sawosz, Adam Liebert
Publicado en: Diffuse Optical Spectroscopy and Imaging VII, 2019, Página(s) 10, ISBN 9781-510628427
Editor: SPIE
DOI: 10.1117/12.2527160

A Performance Comparison between Continuous-Wave and Time-Domain Diffuse Optical Tomography for Deep Inclusions by Using Small Source-Detector Separations

Autores: David Orive-Miguel, Jean-Marc Dinten, Jerome Mars, Laurent Condat and Lionel Hervé
Publicado en: 12e Journées Imagerie Optique Non-Conventionnelle (JIONC 2017), 2017
Editor: HAL

Performance evaluation of time-domain multispectral diffuse optical tomography in the reflection geometry

Autores: Lionel Hervé, Judy Zouaoui, David Orive-Miguel, Laura Di Sieno, Antonio Pifferi, Andrea Farina, Alberto Dalla Mora, Jacques Derouard, Jérôme Mars, Laurent Condat, Jean-Marc Dinten
Publicado en: Diffuse Optical Spectroscopy and Imaging VI, 2017, Página(s) 25, ISBN 9781-510612839
Editor: SPIE
DOI: 10.1117/12.2285811

Hyperspectral Imaging of the Hemodynamic and Metabolic States of the Exposed Cortex: Investigating a Commercial Snapshot Solution

Autores: Luca Giannoni, Frédéric Lange, Andrew L. Davies, Alisha Dua, Britta Gustavson, Kenneth J. Smith, Ilias Tachtsidis
Publicado en: Thews O., LaManna J., Harrison D. (eds) Oxygen Transport to Tissue XL. Advances in Experimental Medicine and Biology, Edición vol. 1072, 2018, Página(s) 13-20, ISBN 978-3-319-91285-1
Editor: Springer International Publishing
DOI: 10.1007/978-3-319-91287-5_3

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