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Contenuto archiviato il 2024-06-18

Application of new technologies and methods in nutrition research – the example of phenotypic flexibility

Obiettivo

NutriTech will build on the foundations of traditional human nutrition research using cutting-edge analytical technologies and methods to comprehensively evaluate the diet-health relationship and critically assess their usefulness for the future of nutrition research and human well-being. Technologies include genomics, transcriptomics, proteomics, metabolomics, laser scanning cytometry, NMR based lipoprotein profiling and advanced imaging by MRI/MRS.

All methods will be applied in an integrated manner to quantify the effect of diet on “phenotypic flexibility”, based on metabolic flexibility (the capacity for the organism to adapt fuel oxidation to fuel availability). However, NutriTech will move beyond the state-of-the-art by applying these integrated methods to assess the underlying and related cell biological and genetic mechanisms and multiple physiological processes of adaptation when homeostasis is challenged. Methods will in the first instance be evaluated within a human intervention study, and the resulting optimal methods will be validated in a number of existing cohorts against established endpoints.

NutriTech will disseminate the harmonised and integrated technologies on a global scale by a large academic network including 6 non-EU partners and by providing an integrated and standardised data storage and evaluation platform. The impact of NutriTech will be multifold and exploitation is crucial as major breakthroughs from our technology and research are expected. This will be achieved by collaboration with a consortium of 8 major food industries and by exploitation of specific technologies by our 6 SME partners. Overall, NutriTech will lay the foundations for successful integration of emerging technologies intro nutrition research.

Campo scientifico

Not validated

Programma(i)

Argomento(i)

Invito a presentare proposte

FP7-KBBE-2011-5
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Meccanismo di finanziamento

CP-IP - Large-scale integrating project

Coordinatore

NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO
Contributo UE
€ 802 014,00
Indirizzo
ANNA VAN BUERENPLEIN 1
2595 DA Den Haag
Paesi Bassi

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Ultimo aggiornamento: 6 Settembre 2024

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Permalink: https://cordis.europa.eu/project/id/289511/it

European Union, 2024