Project description
Virtual Physiological Human
The airways diseases asthma and chronic obstructive pulmonary disease affect over 400 million people world-wide and cause considerable morbidity and mortality. Airways disease costs the European Union in excess of €56 billion per annum. Current therapies are inadequate and we do not have sufficient tools to predict disease progression or response to current or future therapies. Our consortium, Airway Disease PRedicting Outcomes through Patient Specific Computational Modelling (AirPROM), brings together the exisiting clinical consortia (EvA FP7, U-BIOPRED IMI and BTS Severe Asthma), and expertise in physiology, radiology, image analysis, bioengineering, data harmonization, data security and ethics, computational modeling and systems biology. We shall develop an integrated multi-scale model building upon existing models. This airway model will be comprised of an integrated 'micro-scale' and 'macro-scale' airway model informed and validated by 'omic data and ex vivo models at the genome-transcriptome-cell-tissue scale and by CT and functional MRI imaging coupled to detailed physiology at the tissue-organ scale utilising Europe's largest airway disease cohort. Validation will be undertaken cross-sectionally, following interventions and after longitudinal follow-up to incorporate both spatial and temporal dimensions. AirPROM has a comprehensive data management platform and a well-developed ethico-legal framework. Critically, AirPROM has an extensive exploitation plan, involving at its inception and throughout its evolution those that will 'develop' and 'use' the technologies emerging from this project. AirPROM therefore will bridge the critical gaps in our clinical management of airways disease, by providing validated models to predict disease progression and response to treatment and the platform to translate these patient-specific tools, so as to pave the way to improved, personalised management of airways disease.
Fields of science
Call for proposal
FP7-ICT-2009-6
See other projects for this call
Funding Scheme
CP - Collaborative project (generic)Coordinator
UNIVERSITY OF LEICESTER
EU contribution
€ 2 120 019,00
Address
UNIVERSITY ROAD
LE1 7RH Leicester
United Kingdom
LE1 7RH Leicester
United Kingdom
See on map
Region
East Midlands (England)
Leicestershire, Rutland and Northamptonshire
Leicester
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Marie Adams (Ms.)
Links
Total cost
No data
Participants (39)
FluidDA nv
Belgium
EU contribution
€ 578 631,00
Address
Drie Eikenstraat 661
2650 Edegem
2650 Edegem
See on map
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Jan De Backer (Dr.)
Links
Total cost
No data
MATERIALISE NV
Belgium
EU contribution
€ 556 500,00
Address
TECHNOLOGIELAAN 15
3001 Heverlee
3001 Heverlee
See on map
Region
Vlaams Gewest
Prov. Vlaams-Brabant
Arr. Leuven
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Roel Wirix-Speetjens (Mr.)
Links
Total cost
No data
BIOSCI CONSULTING BVBA
Belgium
EU contribution
€ 517 638,00
Address
WEG NAAR GENEUTH 95
3631 Maasmechelen
3631 Maasmechelen
See on map
Region
Vlaams Gewest
Prov. Limburg (BE)
Arr. Tongeren
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Scott Wagers (Dr.)
Links
Total cost
No data
EUROPEAN FEDERATION OF ASTHMA &ALLERGY ASSOCIATIONS IDEELL FORENING
Sweden
EU contribution
€ 81 360,00
Address
RUE DU CONGRES 35
1000 Brussel
1000 Brussel
See on map
Region
Région de Bruxelles-Capitale/Brussels Hoofdstedelijk Gewest
Région de Bruxelles-Capitale/ Brussels Hoofdstedelijk Gewest
Arr. de Bruxelles-Capitale/Arr. Brussel-Hoofdstad
Activity type
Other
Administrative Contact
Susanna Palkonen (Ms.)
Links
Total cost
No data
EUROPEAN RESPIRATORY SOCIETY
Switzerland
EU contribution
€ 112 680,00
Address
AVENUE SAINTE LUCE 4
1003 Lausanne
1003 Lausanne
See on map
Region
Schweiz/Suisse/Svizzera
Région lémanique
Vaud
Activity type
Other
Administrative Contact
Werner Bill (Mr.)
Links
Total cost
No data
BIOMAX INFORMATICS AG
Germany
EU contribution
€ 653 360,00
Address
ROBERT KOCH STRASSE 2
82152 STEINKIRCHEN
82152 STEINKIRCHEN
See on map
Region
Bayern
Oberbayern
München, Landkreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Dieter Maier (Dr.)
Links
Total cost
No data
HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Participation ended
Germany
EU contribution
€ 72 337,00
Address
INGOLSTADTER LANDSTRASSE 1
85764 Neuherberg
85764 Neuherberg
See on map
Region
Bayern
Oberbayern
München, Landkreis
Activity type
Research Organisations
Administrative Contact
Juergen Ertel (Dr.)
Links
Total cost
No data
OBJET GEOMETRIES GMBH
Germany
EU contribution
€ 30 318,00
Address
AIRPORT BOULEVARD B210
77836 RHEINMUNSTER
77836 RHEINMUNSTER
See on map
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Andreas Langfeld (Mr.)
Links
Total cost
No data
FUNDACIO PARC CIENTIFIC DE BARCELONA
Participation ended
Spain
EU contribution
€ 49 320,00
Address
BALDIRI I REIXAC 4
08028 Barcelona
08028 Barcelona
See on map
Region
Este
Cataluña
Barcelona
Administrative Contact
Moises Tarte (Mr.)
Links
Total cost
No data
FUNDACIO CENTRE DE REGULACIO GENOMICA
Spain
EU contribution
€ 410 080,00
Address
CARRER DOCTOR AIGUADER 88
08003 Barcelona
08003 Barcelona
See on map
Region
Este
Cataluña
Barcelona
Activity type
Research Organisations
Administrative Contact
Pedro Corral
Links
Total cost
No data
UNIVERSITE DE LA MEDITERRANEE D'AIX-MARSEILLE II
Participation ended
France
EU contribution
€ 38 000,00
Address
Boulevard Charles Livon, Jardin du Pharo 58
13284 MARSEILLE
13284 MARSEILLE
See on map
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Céline Damon (Ms.)
Links
Total cost
No data
INSTITUT MINES-TELECOM
France
EU contribution
€ 535 799,00
Address
19 PLACE MARGUERITE PEREY
91120 Palaiseau
91120 Palaiseau
See on map
Region
Ile-de-France
Ile-de-France
Essonne
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Patricia Retrou (Ms.)
Links
Total cost
No data
UNIVERSITE D'AIX MARSEILLE
France
EU contribution
€ 0,00
Address
BOULEVARD CHARLES LIVON 58 LE PHARO
13284 Marseille
13284 Marseille
See on map
Region
Provence-Alpes-Côte d’Azur
Provence-Alpes-Côte d’Azur
Bouches-du-Rhône
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Céline Damon (Ms.)
Links
Total cost
No data
COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
France
EU contribution
€ 23 553,00
Address
RUE LEBLANC 25
75015 PARIS 15
75015 PARIS 15
See on map
Region
Ile-de-France
Ile-de-France
Paris
Activity type
Research Organisations
Administrative Contact
Elizabeth May (Ms.)
Links
Total cost
No data
ORSZAGOS KORANYI PULMONOLOGIAI INTEZET
Hungary
EU contribution
€ 53 000,00
Address
KORANYI FRIGYES UT 1
1121 Budapest
1121 Budapest
See on map
Region
Közép-Magyarország
Budapest
Budapest
Activity type
Research Organisations
Administrative Contact
Imre Barta (Dr.)
Links
Total cost
No data
SEMMELWEIS EGYETEM
Hungary
EU contribution
€ 20 500,00
Address
ULLOI UTCA 26
1085 Budapest
1085 Budapest
See on map
Region
Közép-Magyarország
Budapest
Budapest
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ildikó Horváth (Dr.)
Links
Total cost
No data
UNIVERSITA DEGLI STUDI DI CATANIA
Italy
EU contribution
€ 24 800,00
Address
PIAZZA UNIVERSITA 2
95131 Catania
95131 Catania
See on map
Region
Isole
Sicilia
Catania
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Riccardo Polosa (Prof.)
Links
Total cost
No data
UNIVERSITA DEGLI STUDI DI FERRARA
Italy
EU contribution
€ 54 998,00
Address
VIA ARIOSTO 35
44121 Ferrara
44121 Ferrara
See on map
Region
Nord-Est
Emilia-Romagna
Ferrara
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Pier Andrea Borea (Prof.)
Links
Total cost
No data
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
Netherlands
EU contribution
€ 345 300,00
Address
MEIBERGDREEF 15
1105AZ Amsterdam
1105AZ Amsterdam
See on map
Region
West-Nederland
Noord-Holland
Groot-Amsterdam
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Erik Veenstra (Dr.)
Links
Total cost
No data
INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK
Poland
EU contribution
€ 378 640,00
Address
NOSKOWSKIEGO 12-14
61-704 POZNAN
61-704 POZNAN
See on map
Region
Makroregion północno-zachodni
Wielkopolskie
Miasto Poznań
Activity type
Research Organisations
Administrative Contact
Barbara Borgiel (Ms.)
Links
Total cost
No data
INSTYTUT GRUZLICY I CHOROB PLUC
Poland
EU contribution
€ 36 400,00
Address
UL. PLOCKA 26
01138 Warszawa
01138 Warszawa
See on map
Region
Makroregion województwo mazowieckie
Warszawski stołeczny
Miasto Warszawa
Activity type
Research Organisations
Administrative Contact
Adam Nowinski (Dr.)
Links
Total cost
No data
VÄSTRA GÖTALANDSREGIONEN
Sweden
EU contribution
€ 66 800,00
Address
REGIONENS HUS
462 80 Vanersborg
462 80 Vanersborg
See on map
Region
Södra Sverige
Västsverige
Västra Götalands län
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Elisabeth Kenne Sarenmalm (Dr.)
Links
Total cost
No data
UMEA UNIVERSITET
Sweden
EU contribution
€ 17 500,00
Address
UNIVERSITETOMRADET
901 87 Umea
901 87 Umea
See on map
Region
Norra Sverige
Övre Norrland
Västerbottens län
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Lars Lustig (Mr.)
Links
Total cost
No data
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 18 220,00
Address
Nobels Vag 5
17177 Stockholm
17177 Stockholm
See on map
Region
Östra Sverige
Stockholm
Stockholms län
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Per-Olof Larsson (Mr.)
Links
Total cost
No data
GREATER GLASGOW HEALTH BOARD
United Kingdom
EU contribution
€ 50 760,00
Address
GREAT WESTERN ROAD 1055 J B RUSSELL
G12 0XH Glasgow
G12 0XH Glasgow
See on map
Region
Scotland
West Central Scotland
Glasgow City
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Roma Armstrong (Dr.)
Links
Total cost
No data
HEART OF ENGLAND NHS FOUNDATION TRUST
United Kingdom
EU contribution
€ 30 002,00
Address
Bordesley Green East
B9 5SS Birmingham
B9 5SS Birmingham
See on map
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Elizabeth Adey (Ms.)
Links
Total cost
No data
THE UNIVERSITY OF MANCHESTER
United Kingdom
EU contribution
€ 135 800,00
Address
OXFORD ROAD
M13 9PL Manchester
M13 9PL Manchester
See on map
Region
North West (England)
Greater Manchester
Manchester
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Elizabeth Fay (Ms.)
Links
Total cost
No data
THE QUEEN'S UNIVERSITY OF BELFAST
United Kingdom
EU contribution
€ 27 852,00
Address
UNIVERSITY ROAD LANYON BUILDING
BT7 1NN Belfast
BT7 1NN Belfast
See on map
Region
Northern Ireland
Northern Ireland
Belfast
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Liam Heaney (Dr.)
Links
Total cost
No data
UNIVERSITY HOSPITALS COVENTRY AND WARWICKSHIRE NATIONAL HEALTH SERVICE TRUST
United Kingdom
EU contribution
€ 872,00
Address
CLIFFORD BRIDGE ROAD
CV2 2DX Coventry
CV2 2DX Coventry
See on map
Region
West Midlands (England)
West Midlands
Coventry
Activity type
Higher or Secondary Education Establishments
Administrative Contact
David G. Parr (Prof.)
Links
Total cost
No data
THE UNIVERSITY OF SHEFFIELD
United Kingdom
EU contribution
€ 1 587 385,00
Address
FIRTH COURT WESTERN BANK
S10 2TN Sheffield
S10 2TN Sheffield
See on map
Region
Yorkshire and the Humber
South Yorkshire
Sheffield
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Joanne Watson (Ms.)
Links
Total cost
No data
UNIVERSITY OF SOUTHAMPTON
United Kingdom
EU contribution
€ 48 800,00
Address
Highfield
SO17 1BJ Southampton
SO17 1BJ Southampton
See on map
Region
South East (England)
Hampshire and Isle of Wight
Southampton
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ratko Djukanovic (Prof.)
Links
Total cost
No data
EUROPEAN LUNG FOUNDATION
United Kingdom
EU contribution
€ 98 760,00
Address
GLOSSOP ROAD 442
S10 2PX Sheffield
S10 2PX Sheffield
See on map
Region
Yorkshire and the Humber
South Yorkshire
Sheffield
Activity type
Other
Administrative Contact
Anne-Marie Wish (Ms.)
Links
Total cost
No data
ANSYS UK LIMITED
United Kingdom
EU contribution
€ 352 112,00
Address
3 ST PAUL S PLACE 129 NORFOLK STREET
S1 2JE SHEFFIELD
S1 2JE SHEFFIELD
See on map
Region
Yorkshire and the Humber
South Yorkshire
Sheffield
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Justin Penrose (Dr.)
Links
Total cost
No data
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom
EU contribution
€ 1 008 216,00
Address
WELLINGTON SQUARE UNIVERSITY OFFICES
OX1 2JD Oxford
OX1 2JD Oxford
See on map
Region
South East (England)
Berkshire, Buckinghamshire and Oxfordshire
Oxfordshire
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Stephen Conway (Dr.)
Links
Total cost
No data
THE UNIVERSITY OF NOTTINGHAM
United Kingdom
EU contribution
€ 792 818,00
Address
University Park
NG7 2RD Nottingham
NG7 2RD Nottingham
See on map
Region
East Midlands (England)
Derbyshire and Nottinghamshire
Nottingham
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Paul Cartledge (Mr.)
Links
Total cost
No data
UNIVERSITY OF WARWICK
United Kingdom
EU contribution
€ 711 504,00
Address
KIRBY CORNER ROAD UNIVERSITY HOUSE
CV4 8UW COVENTRY
CV4 8UW COVENTRY
See on map
Region
West Midlands (England)
West Midlands
Coventry
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Peter Hedges (Dr.)
Links
Total cost
No data
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
EU contribution
€ 60 200,00
Address
SOUTH KENSINGTON CAMPUS EXHIBITION ROAD
SW7 2AZ LONDON
SW7 2AZ LONDON
See on map
Region
London
Inner London — West
Westminster
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Kian Fan CHUNG (Prof.)
Links
Total cost
No data
ANSYS GERMANY GMBH
Germany
EU contribution
€ 6 180,00
Address
BIRKENWEG 14A
64294 Darmstadt
64294 Darmstadt
See on map
Region
Hessen
Darmstadt
Darmstadt, Kreisfreie Stadt
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Justin Penrose (Dr.)
Links
Total cost
No data
ANSYS FRANCE SAS
France
EU contribution
€ 6 180,00
Address
PLACE GEORGES POMPIDOU 14-15
78180 Montigny Le Bretonneux
78180 Montigny Le Bretonneux
See on map
Region
Ile-de-France
Ile-de-France
Yvelines
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Justin Penrose (Dr.)
Links
Total cost
No data