Objectif
NAMDIATREAM will develop a cutting edge nanotechnology-based toolkit for multi-modal detection of biomarkers of most common cancer types and cancer metastases, permitting identification of cells indicative of early disease onset in a high-specificity and throughput format in clinical, laboratory and point-of-care devices. The project is built on the innovative concepts of super-sensitive and highly specific “lab-on-a-bead”, “lab-on-a-chip” and “lab-on-a-wire” nano-devices utilizing photoluminescent, plasmonic, magnetic and non-linear optical properties of nanomaterials. This offers groundbreaking advantages over present technologies in terms of stability, sensitivity, time of analysis, probe multiplexing, assay miniaturisation and reproducibility. The ETP in Nanomedicine documents point out that nanotechnology has yet to deliver practical solutions for the patients and clinicians in their struggle against common, socially and economically important diseases such as cancer. Over 3.2M new cases and 1.7M cancer-related deaths are registered in Europe every year, largely because diagnostic methods have an insufficient level of sensitivity, limiting their potential for early disease identification. We will deliver •Photoluminescent nanoparticle-based reagents and diagnostic chips for high throughput early diagnosis of cancer and treatment efficiency assessment •Nanocrystals enabling plasmon-optical and nonlinear optical monitoring of molecular receptors within body fluids or on the surface of cancer cell •Multi-Parameter screening of cancer biomarkers in diagnostic material implementing segmented magnetic nanowires •Validation of nano-tools for early diagnosis and highly improved specificity in cancer research. •OECD-compliant nanomaterials with improved stability, signal strength and biocompatibility Direct lead users of the results will be the diagnostic and medical imaging device companies involved in the consortium, clinical and academic partners
Champ scientifique
- engineering and technologyother engineering and technologiesmicrotechnologylab on a chip
- medical and health sciencesmedical biotechnologynanomedicine
- engineering and technologynanotechnologynano-materialsnanocrystals
- medical and health sciencesclinical medicineoncology
- engineering and technologymedical engineeringdiagnostic imaging
Programme(s)
Thème(s)
Appel à propositions
FP7-NMP-2009-LARGE-3
Voir d’autres projets de cet appel
Régime de financement
CP-IP - Large-scale integrating projectCoordinateur
D02 CX56 DUBLIN 2
Irlande
Voir sur la carte
Participants (22)
Participation terminée
20018 San Sebastian
Voir sur la carte
1210 Wien
Voir sur la carte
1211 Geneve
Voir sur la carte
35037 Marburg
Voir sur la carte
4 Dublin
Voir sur la carte
75654 Paris
Voir sur la carte
31077 TOULOUSE CEDEX 4
Voir sur la carte
38106 Braunschweig
Voir sur la carte
1015 Lausanne
Voir sur la carte
73011 Chambery
Voir sur la carte
80539 Munchen
Voir sur la carte
38800 Le Pont De Claix
Voir sur la carte
94504 CHAMPIGNY SUR MARNE CEDEX
Voir sur la carte
48160 VIZCAYA BIZKAIA
Voir sur la carte
00131 Roma
Voir sur la carte
D12 EK79 Dublin
Voir sur la carte
NE2 4HH Newcastle upon Tyne
Voir sur la carte
SP4 7RT WILTSHIRE
Voir sur la carte
IP31 HF29 Cork
Voir sur la carte
01630 Saint Genis Pouilly
Voir sur la carte
55716 IDAR OBERSTEIN
Voir sur la carte
51100 Reims
Voir sur la carte