Objective
NAMDIATREAM will develop a cutting edge nanotechnology-based toolkit for multi-modal detection of biomarkers of most common cancer types and cancer metastases, permitting identification of cells indicative of early disease onset in a high-specificity and throughput format in clinical, laboratory and point-of-care devices. The project is built on the innovative concepts of super-sensitive and highly specific “lab-on-a-bead”, “lab-on-a-chip” and “lab-on-a-wire” nano-devices utilizing photoluminescent, plasmonic, magnetic and non-linear optical properties of nanomaterials. This offers groundbreaking advantages over present technologies in terms of stability, sensitivity, time of analysis, probe multiplexing, assay miniaturisation and reproducibility. The ETP in Nanomedicine documents point out that nanotechnology has yet to deliver practical solutions for the patients and clinicians in their struggle against common, socially and economically important diseases such as cancer. Over 3.2M new cases and 1.7M cancer-related deaths are registered in Europe every year, largely because diagnostic methods have an insufficient level of sensitivity, limiting their potential for early disease identification. We will deliver •Photoluminescent nanoparticle-based reagents and diagnostic chips for high throughput early diagnosis of cancer and treatment efficiency assessment •Nanocrystals enabling plasmon-optical and nonlinear optical monitoring of molecular receptors within body fluids or on the surface of cancer cell •Multi-Parameter screening of cancer biomarkers in diagnostic material implementing segmented magnetic nanowires •Validation of nano-tools for early diagnosis and highly improved specificity in cancer research. •OECD-compliant nanomaterials with improved stability, signal strength and biocompatibility Direct lead users of the results will be the diagnostic and medical imaging device companies involved in the consortium, clinical and academic partners
Fields of science
Not validated
Not validated
- engineering and technologyother engineering and technologiesmicrotechnologylab on a chip
- medical and health sciencesmedical biotechnologynanomedicine
- engineering and technologynanotechnologynano-materialsnanocrystals
- medical and health sciencesclinical medicineoncology
- engineering and technologymedical engineeringdiagnostic imaging
Programme(s)
Topic(s)
Call for proposal
FP7-NMP-2009-LARGE-3
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Funding Scheme
CP-IP - Large-scale integrating projectCoordinator
D02 CX56 Dublin
Ireland
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Participants (22)
Participation ended
20018 San Sebastian
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1210 Wien
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1211 Geneve
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35037 Marburg
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4 Dublin
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75654 Paris
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31077 Toulouse
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38106 Braunschweig
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1015 Lausanne
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73011 Chambery
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80539 Munchen
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38800 Le Pont De Claix
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94504 CHAMPIGNY SUR MARNE CEDEX
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48160 VIZCAYA BIZKAIA
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00131 Roma
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D12 EK79 Dublin
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NE2 4HH Newcastle upon Tyne
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SP4 7RT WILTSHIRE
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IP31 HF29 Cork
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01630 Saint Genis Pouilly
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55716 IDAR OBERSTEIN
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51100 Reims
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