NANOTECHNOLOGICAL TOOLKITS FOR MULTI-MODAL DISEASE DIAGNOSTICS AND TREATMENT MONITORING

Project Information

NAMDIATREAM

Grant agreement ID: 246479

Project closed

Start date 1 July 2010

End date 30 June 2014

Funded under

• Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies

Total cost € 16 519 663,20

EU contribution € 11 999 205,00

Coordinated by

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Ireland

Objective

NAMDIATREAM will develop a cutting edge nanotechnology-based toolkit for multi-modal detection of biomarkers of most common cancer types and cancer metastases, permitting identification of cells indicative of early disease onset in a high-specificity and throughput format in clinical, laboratory and point-of-care devices. The project is built on the innovative concepts of super-sensitive and highly specific “lab-on-a-bead”, “lab-on-a-chip” and “lab-on-a-wire” nano-devices utilizing photoluminescent, plasmonic, magnetic and non-linear optical properties of nanomaterials. This offers groundbreaking advantages over present technologies in terms of stability, sensitivity, time of analysis, probe multiplexing, assay miniaturisation and reproducibility. The ETP in Nanomedicine documents point out that nanotechnology has yet to deliver practical solutions for the patients and clinicians in their struggle against common, socially and economically important diseases such as cancer. Over 3.2M new cases and 1.7M cancer-related deaths are registered in Europe every year, largely because diagnostic methods have an insufficient level of sensitivity, limiting their potential for early disease identification. We will deliver •Photoluminescent nanoparticle-based reagents and diagnostic chips for high throughput early diagnosis of cancer and treatment efficiency assessment •Nanocrystals enabling plasmon-optical and nonlinear optical monitoring of molecular receptors within body fluids or on the surface of cancer cell •Multi-Parameter screening of cancer biomarkers in diagnostic material implementing segmented magnetic nanowires •Validation of nano-tools for early diagnosis and highly improved specificity in cancer research. •OECD-compliant nanomaterials with improved stability, signal strength and biocompatibility Direct lead users of the results will be the diagnostic and medical imaging device companies involved in the consortium, clinical and academic partners

Fields of science

• engineering and technology › other engineering and technologies › microtechnology › lab on a chip
• medical and health sciences › medical biotechnology › nanomedicine
• engineering and technology › nanotechnology › nano-materials › nanocrystals
• medical and health sciences › clinical medicine › oncology
• engineering and technology › medical engineering › diagnostic imaging

Programme(s)

• FP7-NMP - Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies

Topic(s)

• NMP-2009-4.0-3 - Development of nanotechnology-based systems for molecular diagnostics and imaging

Call for proposal

FP7-NMP-2009-LARGE-3
See other projects for this call

Funding Scheme

CP-IP - Large-scale integrating project

Coordinator

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN

• EU contribution: € 2 438 665,90
• Address: COLLEGE GREEN TRINITY COLLEGE ; D02 CX56 Dublin ; Ireland
• Region: Ireland › Eastern and Midland › Dublin
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Deirdre Savage (Ms.)
• Total cost: No data

Participants (22)

ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN NANOCIENCIAS CIC NANOGUNE

Participation ended

Spain

• EU contribution: € 69 667,00
• Address: TOLOSA HIRIBIDEA 76 ; 20018 San Sebastian
• Region: Noreste › País Vasco › Gipuzkoa
• Activity type: Research Organisations
• Administrative Contact: Miguel Odriozola (Mr.)
• Total cost: No data

AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH

Austria

• EU contribution: € 692 912,00
• Address: GIEFINGGASSE 4 ; 1210 Wien
• Region: Ostösterreich › Wien › Wien
• Activity type: Research Organisations
• Administrative Contact: Felix Schropfer (Mr.)
• Total cost: No data

UNIVERSITE DE GENEVE

Switzerland

• EU contribution: € 728 240,00
• Address: RUE DU GENERAL DUFOUR 24 ; 1211 Geneve
• Region: Schweiz/Suisse/Svizzera › Région lémanique › Genève
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Pierre Spierer (Prof.)
• Total cost: No data

PHILIPPS UNIVERSITAET MARBURG

Germany

• EU contribution: € 444 400,00
• Address: BIEGENSTRASSE 10 ; 35037 Marburg
• Region: Nordrhein-Westfalen › Arnsberg › Hochsauerlandkreis
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Wolfgang Parak (Prof.)
• Total cost: No data

UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN

Ireland

• EU contribution: € 496 102,00
• Address: BELFIELD ; 4 Dublin
• Region: Ireland › Eastern and Midland › Dublin
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Donal Doolan (Mr.)
• Total cost: No data

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

• EU contribution: € 463 470,00
• Address: RUE DE TOLBIAC 101 ; 75654 Paris
• Region: Ile-de-France › Ile-de-France › Paris
• Activity type: Research Organisations
• Administrative Contact: Dominique Nobile (Mr.)
• Total cost: No data

INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE

France

• EU contribution: € 466 583,00
• Address: AVENUE DE RANGUEIL 135 ; 31077 Toulouse
• Region: Occitanie › Midi-Pyrénées › Haute-Garonne
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Didier Marquis (Prof.)
• Total cost: No data

TECHNISCHE UNIVERSITAET BRAUNSCHWEIG

Germany

• EU contribution: € 464 140,00
• Address: UNIVERSITAETSPLATZ 2 ; 38106 Braunschweig
• Region: Niedersachsen › Braunschweig › Braunschweig, Kreisfreie Stadt
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Meinhard Schilling (Prof.)
• Total cost: No data

ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE

Switzerland

• EU contribution: € 597 633,00
• Address: BATIMENT CE 3316 STATION 1 ; 1015 Lausanne
• Region: Schweiz/Suisse/Svizzera › Région lémanique › Vaud
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Paul Joseph Dyson (Prof.)
• Total cost: No data

UNIVERSITE SAVOIE MONT BLANC

France

• EU contribution: € 278 912,00
• Address: RUE MARCOZ 27 DOMAINE UNIVERSITAIRE ; 73011 Chambery
• Region: Auvergne-Rhône-Alpes › Rhône-Alpes › Savoie
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Philippe Carron (Dr.)
• Total cost: No data

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV

Germany

• EU contribution: € 448 500,00
• Address: HOFGARTENSTRASSE 8 ; 80539 Munchen
• Region: Bayern › Oberbayern › München, Kreisfreie Stadt
• Activity type: Research Organisations
• Administrative Contact: Nils Brose (Prof.)
• Total cost: No data

BECTON DICKINSON FRANCE SAS

France

• EU contribution: € 499 200,00
• Address: RUE ARISTIDE BERGES 11 ; 38800 Le Pont De Claix
• Region: Auvergne-Rhône-Alpes › Rhône-Alpes › Isère
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Emiel Jans (Mr.)
• Total cost: No data

NIKON FRANCE SAS

France

• EU contribution: € 319 435,60
• Address: RUE DU MARCHE ROLLAY 191 ; 94504 CHAMPIGNY SUR MARNE CEDEX
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Valerie Le Lay (Ms.)
• Total cost: No data

PROGENIKA BIOPHARMA SA

Spain

• EU contribution: € 667 280,00
• Address: PARQUE IBAIZABAL BIDEA EDIFICIO 504 PARQUE TECNOLOGICO DERIO ; 48160 VIZCAYA BIZKAIA
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Maria Martinez (Ms.)
• Total cost: No data

INNOVA SRL

Italy

• EU contribution: € 435 257,50
• Address: VIA GIACOMO PERONI 386 ; 00131 Roma
• Region: Centro (IT) › Lazio › Roma
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Francesca Stinelli (Ms.)
• Total cost: No data

CELLIX LIMITED

Ireland

• EU contribution: € 435 020,00
• Address: Unit 1, Longmile Business Park, Longmile Rd ; D12 EK79 Dublin
• Region: Ireland › Eastern and Midland › Dublin
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Vivienne Williams (Ms.)
• Total cost: No data

Selective Antibodies Limited

United Kingdom

• EU contribution: € 677 080,00
• Address: CELS at Newcastle William Leech Building Framlington Place ; NE2 4HH Newcastle upon Tyne
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Colin Self (Prof.)
• Total cost: No data

NANOSIGHT LIMITED

United Kingdom

• EU contribution: € 97 950,00
• Address: LONDON ROAD MINTON PARK ; SP4 7RT WILTSHIRE
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Jeremy Warren (Mr.)
• Total cost: No data

RADISENS DIAGNOSTICS LIMITED

Ireland

• EU contribution: € 465 650,00
• Address: UNITS 1-3 WESTPOINT BUILDINGS LINK ROAD BALLINCOLL ; IP31 HF29 Cork
• Region: Ireland › Southern › South-East
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Jerry O'brien (Mr.)
• Total cost: No data

Advanced Accelerator Applications

France

• EU contribution: € 333 954,00
• Address: Rue Diesel 20 ; 01630 Saint Genis Pouilly
• Region: Auvergne-Rhône-Alpes › Rhône-Alpes › Ain
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Heinz Mausli (Dr.)
• Total cost: No data

FORSCHUNGSINSTITUT FUR MINERALISCHEUND METALLISCHE WERKSTOFFE EDELSTEINE/EDELMETALLE GMBH

Germany

• EU contribution: € 274 913,00
• Address: STRUTHSTRASSE 2 ; 55716 IDAR OBERSTEIN
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Daniel Rytz (Dr.)
• Total cost: No data

UNIVERSITE DE REIMS CHAMPAGNE-ARDENNE

France

• EU contribution: € 204 240,00
• Address: 2 AVENUE ROBERT SCHUMAN ; 51100 Reims
• Region: Grand Est › Champagne-Ardenne › Marne
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Nathalie Rau (Mrs.)
• Total cost: No data