Skip to main content
European Commission logo
español español
CORDIS - Resultados de investigaciones de la UE
CORDIS
CORDIS Web 30th anniversary CORDIS Web 30th anniversary
Contenido archivado el 2024-06-18

Function and dynamics of Lmo4-containing complexes during erythropoiesis

Objetivo

Anemias and erythroid malignancies caused by impaired formation of erythrocytes (red blood cells) are common disorders. These diseases have a severe impact on the quality of life of the patients. It is essential to unravel the molecular mechanisms underlying erythropoiesis (the development of red blood cells) to be able to fully understand the etiology of these diseases and to devise novel treatments. The most important part of understanding the molecular mechanisms of erythropoiesis is the unraveling of its transcription factor network and studying how this network responds to outside signals. I propose to analyze the function and dynamics of this network through a study of the factors that are part of the Ldb1/Gata1 complex, and in particular the function of the LMO4 protein.

Convocatoria de propuestas

FP7-PEOPLE-2007-2-1-IEF
Consulte otros proyectos de esta convocatoria

Coordinador

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Aportación de la UE
€ 165 996,12
Dirección
DR MOLEWATERPLEIN 40
3015 GD Rotterdam
Países Bajos

Ver en el mapa

Región
West-Nederland Zuid-Holland Groot-Rijnmond
Tipo de actividad
Higher or Secondary Education Establishments
Contacto administrativo
Riet Van Zeijl (Ms.)
Enlaces
Coste total
Sin datos