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ALGAE4IBD –FROM NATURE TO BEDSIDE- ALGAE BASED BIO COMPOUND FOR PREVENTION AND TREATMENT OF INFLAMMATION, PAIN AND IBD

Project description

Diving deep to find anti-inflammatory algae

What if the solution for a chronic disease lies in our ocean, rivers, or lakes? The EU-funded Algae4IBD project will answer this question. Studying compounds from marine and freshwater micro and macroalgae (seaweed) from lab/pilot to market scale, the project will comprehensively research means to transform aquatic natural biological resources into biologically active compounds for the prevention and treatment of inflammatory bowel disease (IBD). Specifically, it will develop algae-based compounds while ensuring algae biodiversity preservation through pioneering cultivation and extraction technologies. Algae4IBD proposes innovative solutions to sustainably use algae-based products with improved nutritional quality to positively impact IBD patients.

Objective

Algae4IBD's mission is to develop commercial products for Inflammatory Bowel Disease (IBD) prevention and treatment using aquatic natural biological resources. With the emerging developments in natural product, notable success has been achieved in discovering natural products and their synthetic structural analogues with anti-inflammatory activity. However, global biodiversity remains a largely unexploited resource for natural bioactive molecules with an enormous potential for developing commercial products with public health benefits. Micro and macroalgae, found in marine and freshwater, have been identified as promising sources of bioactive compounds including small molecules and secondary metabolites with a wide range of bioactivities as an antioxidant, anti-inflammatory and cancer preventive. Consumption of algae could, therefore, provide defence against chronic inflammatory diseases such as IBD, that until date have no effective cure. This project offers nature to bedside approach, using an entire development along the value chain for a new biodiscovery therapeutic approach by developing and examining algae-based compounds for IBD patients while guaranteeing algae's biodiversity preservation. We propose innovative solutions for increasing the use of algae-based ingredients and to ensure the science-based improvement of nutritional quality and its effect on public health. The researchers, companies and hospitals involved in the different stages of the project will use the biodiversity of algae, both micro and macro, as a wide source for bioactive compounds using state-of-the-art cultivation and extraction technologies for obtaining sufficient amounts of the bio-active molecules together with novel processing protocols. It will result in novel algal-based, high-quality bioactive compounds at GMP grade and lower costs for dual purposes – IBD prevention and treatment in relevance to the food as well as the pharmaceutical industries.

Call for proposal

H2020-FNR-2020

See other projects for this call

Sub call

H2020-FNR-2020-2

Coordinator

MIGAL GALILEE RESEARCH INSTITUTE LTD
Net EU contribution
€ 1 177 948,49
Address
SOUTH INDUSTRIAL ZONE
11016 KIRYAT SHEMONA
Israel

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost
€ 1 177 948,49

Participants (23)