Objetivo
Hyper solutes, compatible solutes from hyperthermophiles, are superior to their mesospheric counterparts in the preservation of the performance of a wide variety of biomaterials, ranging from proteins to whole cells, skin and artificial tissues. A major bottleneck for industrial applications of hyper solutes is the large-scale production at a competitive cost. The major goal of this project is the development of cell systems eternised for the production of mannosylglycerate; the most widely distributed hyper solute. Two strategies will be pursued:
i) engineering of expression and secretion systems in suitable hosts;
ii) optimisation of fermentation of natural producers. Trials will be conducted that will widen the range of application of mannosylglycerate. The involvement of industrial partners ensures that the results will reach end-users.
Ámbito científico
Convocatoria de propuestas
Data not availableRégimen de financiación
CSC - Cost-sharing contractsCoordinador
OEIRAS
Portugal