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Immunological mechanisms of protection against classical swine fever virus: towards the development of new efficacious marker vaccines

Ziel

The high costs of a Classical Swine Fever (CSF) -outbreak, the social impact and resistance against destruction of pigs have led to reconsideration of emergency vaccination against CSF. The application of marker vaccines that can provide early protection might contribute to improved intervention and control strategies and might limit the duration and costs of an outbreak. The objective of this project is to understand the immune mechanisms underlying protection against CSF, in particular the mechanisms involved in early protection against clinical signs of CSF and in the reduction of (horizontal) virus transmission. The knowledge about relevant viral components, and about the quality of the vaccine-induced immune response may contribute to the future development of new and safe marker vaccines that can induce a fast protective immune response.

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Koordinator

ID LELYSTAD - INSTITUTE FOR ANIMAL HEALTH AND SCIENCE
EU-Beitrag
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Adresse
Edelhertweg 15
8200 AB LELYSTAD
Niederlande

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